LOCUS       NZ_VOGX01000018        22286 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77 scaffold11_cov50_1_2691061,
            whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000018
VERSION     NZ_VOGX01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   3  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
REFERENCE   4  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1805959
            Orig. end                         :: 1828245
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000018.1.
            Bacteria and source DNA available from MEB Lab.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22286
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22286
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22286
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12286](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12286
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(21..37)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            53..535
                     /locus_tag="FRZ02_RS10060"
                     /old_locus_tag="FRZ02_10060"
     CDS             53..535
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-154). E-value: 4e-20.
                     Score: 64.6. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS10060_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414939.1"
                     /locus_tag="FRZ02_RS10060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10060"
                     /product="SRPBCC family protein"
                     /protein_id="WP_026048269.1"
                     /transl_table=11
                     /translation="MRSTAEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVG
                     PAPVGAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDG
                     TATEVTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLEAERRAG"
     aSDomain        65..514
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS10060_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.00E-20"
                     /label="FRZ02_RS10060_Polyketide_cyc2.1"
                     /locus_tag="FRZ02_RS10060"
                     /protein_end="154"
                     /protein_start="4"
                     /score="64.6"
                     /tool="antismash"
                     /translation="AEVSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGPAPV
                     GAEFKGTNKGPSGRSWSTRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDGTATE
                     VTETAVDQRNRLLWFLGSAVSGVWDRSAHNAETMRETLERLRETLE"
     gene            687..1364
                     /locus_tag="FRZ02_RS10065"
                     /old_locus_tag="FRZ02_10065"
     CDS             687..1364
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414941.1"
                     /locus_tag="FRZ02_RS10065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10065"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_008414941.1"
                     /transl_table=11
                     /translation="MSDHGTTGTAGDEARARAVRDAWARIDAWMRAHAPDSYEVLAPPA
                     DPAAVEAAQAEMGVGFPADLLASLACHDGLRHWDNCLPLRPPEPVARIVDHWQMCVEID
                     EDNRADEDEPEPEGEEPWWHPQWIPWAQSDGDAQIIDMRPGPAQGRLGMAYHDDCGVFT
                     GGWPSLAAYLTEVADVLEKGGAVGGTWAPFLTTEGELWWSLKGETQLNGEPLVPAPAPA
                     AGT"
     gene            1445..3115
                     /gene="murJ"
                     /locus_tag="FRZ02_RS10070"
                     /old_locus_tag="FRZ02_10070"
     CDS             1445..3115
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0034204 - lipid translocation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="murJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414943.1"
                     /locus_tag="FRZ02_RS10070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10070"
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="WP_146580812.1"
                     /transl_table=11
                     /translation="MTQGADSAVRARTAEGRAKSAGGGLARSSLLMAVGTVVSRATGLI
                     RQVLQAAALGTGLLASTYNTANTVPTSLYTLLIGGALNAVLVPQLVRARATEPDGGRAY
                     EQRLVTLVVCVLGMGTALAVWAAPEIVGLYMRDTPGSHEAFELTVTFARFLLPQIFFYG
                     LFGIYGQVLNAREKFGAMMWTPVLNNVVLVAMFAAYLGLMVAPGRVEDITADQVRLLGI
                     GTTAGVALQALALVPFARAAGFRFRPRFDWRGTGLGRSVHAAKWTLLFVLANQVALTVV
                     THFANAADQELPEAGAGYTAYMYAQTIWLLPQSIVTVSLVTALLPRMSRAVADGRVGDL
                     RADLTRGLRISGVVIVPTAFLFLALGPQIAALLFAHGAADAASVRPLGQMLQAFGPGLI
                     AFSAQYLLLRGFYAYEDTRTPFFMAAWIAGVDIALASACHLLLPARWAVVGMAGAYTLS
                     YLAGLALTARLLRRRLGGRIGTGGLGRAYGKVLCAAVPAAGLGWAAARALSGPGGPGAA
                     GTWSTAVALASGVLSTAVAYLLLARLLKVEEVRRLPGLR"
     gene            complement(3151..3936)
                     /locus_tag="FRZ02_RS10075"
                     /old_locus_tag="FRZ02_10075"
     CDS             complement(3151..3936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414944.1"
                     /locus_tag="FRZ02_RS10075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10075"
                     /product="hypothetical protein"
                     /protein_id="WP_008414944.1"
                     /transl_table=11
                     /translation="MTRKTLWRTAVAGGAAAVFTGLAAVPAGAAEGGVSFTRVKVNNGQ
                     PIVLGVKEIVEIPASVRMTTRRKFDGGPVVYPYRNTPAGVGDALWSSIHTSDPKVVDKA
                     KGIYDFDLSIHIDPRHKDVTNGDTGTWRTRAEMWLADGTYDMDDENLPLQVKRATRLTV
                     NATPEPVTKGKTLTVKGAVTRANWDTHTYQGYAGRTVSLQFKPSGASSYKTVKKVTSGS
                     KGVLKTTVKATESGTWRWTYYGNSTSGARSSSGDHVALR"
     gene            4122..4736
                     /locus_tag="FRZ02_RS10080"
                     /old_locus_tag="FRZ02_10080"
     CDS             4122..4736
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642002.1"
                     /locus_tag="FRZ02_RS10080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10080"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_146580815.1"
                     /transl_table=11
                     /translation="MSDDEAGQAGAEAVRAAWGRIDAWLRKWGPDSYARLAPPAEPGAV
                     AAAEAALRMRFPAELRASLGCHDGVGGEGVLPVKPPLSAAGIVRYWTRWMELTEEEREF
                     GDPEEEGEPSWHPRWIPWAESDGDAQIIDGRDGPGFGRLGMKYHDEEGSFGDDAPSLAA
                     YLTEVADALENGRSVGGRVPYVGVSGEMWWAEAPAAPSGGG"
     gene            complement(4761..5573)
                     /locus_tag="FRZ02_RS10085"
                     /old_locus_tag="FRZ02_10085"
     CDS             complement(4761..5573)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642004.1"
                     /locus_tag="FRZ02_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10085"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_186785111.1"
                     /transl_table=11
                     /translation="MPDTTDAEGLTVGQVSARLDVTVRALHHWDEIGLARPSLRTPAGY
                     RLYTAPDLERLHRIVVYRELGLGLDKIRSVLDDSATDVPAALRAQRAQIAARIDRLRQL
                     AAGLDRMIDAHEHGLLLTAEQQAAIFGPGWSPDGPVQARQRYGDTTQWRQYAERSASRT
                     PEEWQAVADDTARLERALGEAMDAGVTPGSPEANHLVERHREVFASYFPLSRQMQVCLG
                     RMYESDPGFAAHHDAIRPGLATWFRQLVDAAARAHGIDPETATWEEDR"
     gene            complement(5566..6108)
                     /locus_tag="FRZ02_RS10090"
                     /old_locus_tag="FRZ02_10090"
     CDS             complement(5566..6108)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642006.1"
                     /locus_tag="FRZ02_RS10090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10090"
                     /product="VOC family protein"
                     /protein_id="WP_146580819.1"
                     /transl_table=11
                     /translation="MSDHTYYNAFEISPVPAPGPDAVAPEPFRGIYGMPAFVNIPTTDL
                     AASVEFWTRGLGFFELFSIPGTLVHLRRWAFQDVLLVAAESVPDQPPAMSFSFSGVLSE
                     VDSLVAACRALRPDAVEGPRDTPWNTRDVEVVTPENARIVFTAAKPFDPDTQEARNLEA
                     IGITPPGGTPGDNERHA"
     gene            6318..6641
                     /locus_tag="FRZ02_RS10095"
                     /old_locus_tag="FRZ02_10095"
     CDS             6318..6641
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893452.1"
                     /locus_tag="FRZ02_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10095"
                     /product="hypothetical protein"
                     /protein_id="WP_261399560.1"
                     /transl_table=11
                     /translation="MIDGLPAGTLAELARLERTRNYLWPGAVSEALRTWAAHVRLPRGR
                     TWPRQQDGPCYCCPDPRESRELLDRVARALSRRAARELRRVLAGHDQLWDPAPRPYRGE
                     GPW"
     gene            complement(6658..7251)
                     /locus_tag="FRZ02_RS10100"
                     /old_locus_tag="FRZ02_10100"
     CDS             complement(6658..7251)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414949.1"
                     /locus_tag="FRZ02_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10100"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_015507048.1"
                     /transl_table=11
                     /translation="MDKRPYHHGDLRAALLARAGETLREGGVGALSLRELARDVGVSPG
                     APRRHFASKQVLLDALALDGFERLIDSLVAARGGEARPFAERLDAMARAYVGFSLSDPA
                     LLSLMFSAKHSPEASEGLRDAARRWAEQGLALIRDGQSRGEVREGPPDRVALTVLAPLH
                     GYIGLAAGGAPLPQTPDRGLDDVIASVVRACAPE"
     misc_feature    7287..7305
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.93"
                     /tool="antismash"
     gene            7371..8315
                     /locus_tag="FRZ02_RS10105"
                     /old_locus_tag="FRZ02_10105"
     CDS             7371..8315
                     /NRPS_PKS="Domain: PKS_KR (18-105). E-value: 9.2e-09.
                     Score: 27.4. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS10105_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893454.1"
                     /locus_tag="FRZ02_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10105"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_146580821.1"
                     /transl_table=11
                     /translation="MSRKPVDLTLPDLSGRRAVVTGASDGLGLGLAARLAQAGAEVILP
                     VRNQEKGRAALEEIRRGAPGAEVSLRELDLSSLASVAALGEALRAEDRPVHLLVNNAGV
                     MTPPERRTTADGFELQFGTNHLGHFALTAHLLPLLRAGRARVTSQISVAADRNAINWED
                     PNWESSYNGMKAYSHSKIAFGLFGLELERRARAHDWGLTSNLSHPGVAPTSLLAARPEV
                     GRAKDTTGRRFIKALSARGILLGTVESAKFPALYAATAPEAGGGRLYGPSGPGHLGGPP
                     AEQKLYSRLRSIEDARRVWRLSEELTGVTFPGN"
     CDS_motif       7425..7493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS10105_0001"
                     /evalue="3.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="FRZ02_RS10105"
                     /protein_end="41"
                     /protein_start="18"
                     /score="10.1"
                     /tool="antismash"
                     /translation="VVTGASDGLGLGLAARLAQAGAE"
     aSDomain        7425..7685
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS10105_PKS_KR.1"
                     /evalue="9.20E-09"
                     /label="FRZ02_RS10105_PKS_KR.1"
                     /locus_tag="FRZ02_RS10105"
                     /protein_end="105"
                     /protein_start="18"
                     /score="27.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVTGASDGLGLGLAARLAQAGAEVILPVRNQEKGRAALEEIRRGA
                     PGAEVSLRELDLSSLASVAALGEALRAEDRPVHLLVNNAGVM"
     gene            complement(8296..8721)
                     /locus_tag="FRZ02_RS10110"
                     /old_locus_tag="FRZ02_10110"
     CDS             complement(8296..8721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414951.1"
                     /locus_tag="FRZ02_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10110"
                     /product="ATP-binding protein"
                     /protein_id="WP_049978615.1"
                     /transl_table=11
                     /translation="MKTETGLPAHCERFYRRERRSVPAARDFTAAVLNEWDARVPRDDV
                     LLCVSELATNALLHGVPPGRGFRLFVLRADDGGVRVEVHDSGDGHPATRAPGDEAESGR
                     GLLLVSALADDWGVGERNPGKIVWCSFRPVGVSCPGR"
     gene            8834..9658
                     /locus_tag="FRZ02_RS10115"
                     /old_locus_tag="FRZ02_10115"
     CDS             8834..9658
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414952.1"
                     /locus_tag="FRZ02_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10115"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_018893456.1"
                     /transl_table=11
                     /translation="MQQRKKSSKKVTSWEVLGKQLAEFRRVAGLTQGQLAERAQVGEDT
                     VSSVEQGRRRLQADLAERLDTILETKQALSTAVSTIPTHERFPLFVQDFIEHEQRAITL
                     LSYENHLIPGLLQTPEYARAVFNNSYPPIPAQEVEESAQARIDRQQILSSGKPPMMSFI
                     IEESVLQRHLGDPEAMRRQIEHLRACADLPFLSLQIMPTDTDAHAGLAGPLVLLETPEH
                     DHLAYIEGQYKGVMVEDPDEVSMFQQKYGMLRAQALTPHKTKALLDTLLGVT"
     gene            9655..9921
                     /locus_tag="FRZ02_RS10120"
                     /old_locus_tag="FRZ02_10120"
     CDS             9655..9921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642012.1"
                     /locus_tag="FRZ02_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10120"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_067415920.1"
                     /transl_table=11
                     /translation="MTGAPSRNEPLSWFKSSYSSDTGGNCIEVAYNWRKSSHSSDAGGA
                     CVEVAAHPTTVHVRDSKVPAGPTLDVTPAAWAAFVHATAGPLV"
     gene            10001..12286
                     /locus_tag="FRZ02_RS10125"
                     /old_locus_tag="FRZ02_10125"
     CDS             10001..12286
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414954.1"
                     /locus_tag="FRZ02_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10125"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_164837348.1"
                     /sec_met_domain="T1TS (E-value: 8.3e-82, bitscore: 272.9,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFVLPDFYVPYPARLNPHLEEARAHARVWADEMGMLEGSGIW
                     DLADLEAHDYALLCAYTHPDCDGPALSLVTDWYVWVFFFDDHFLELFKRTQDREGAKAY
                     LERLPAFMPMDLADGFPEPENPVEAGLADLWARTVPAMSEDWRRRFALSTENLLNESMW
                     ELSNINAGRVSNPLEYIEMRRKVGGAPWSAGLIEYAAQAEVPEAVAYSRPLRVLTDAFS
                     DGVHLRNDLFSYQREVEEEGELSNGVLVLERFLECTTQEAAEAVNDLLTSRLQQFENTA
                     LTELGPLFADKGLNPAESASVLAYVKGLQDWQSGGHEWHMRSSRYMNEGAVDGEAAPPT
                     PGGSPGALAAALLGGTLGTSALDVRAFFGRPARQRARSFSHVPYQRTGASLLPDFKLPF
                     PTRLSPALEQSRVDTVEWAHRMGLLVPQPGVPGSDVWDEEALAGYDFPLCAAGLHPEAD
                     LEELNLASQWLTWGTYGDDYYPAVFGRARNFAGAKLCTDRLRDFMPVEQPSAGPVPTSA
                     LERSLADLWVRTASAMPEKARRAFRQTIEVMLDSWVWELDNQAIGRIPDPIDYMEMRRA
                     TFGSDLTMSLCRLRHGNIVPEEVYRSGTIQAMEKAVSDYGALINDVFSYQKEVEFEGEI
                     HNAVLVTQNFFDCDYPTGLAYVDALMNARLEQFEHIVAHELPVLYEDFQLDGAARKVLD
                     GYVRQLENWLSAILTWHRGCKRYKEEDLSHHSPGVRRVIEAAPRGIGPNGLGASSLGTA
                     AARVFAGG"
     gene            complement(12321..13688)
                     /locus_tag="FRZ02_RS10130"
                     /old_locus_tag="FRZ02_10130"
     CDS             complement(12321..13688)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010642015.1"
                     /locus_tag="FRZ02_RS10130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10130"
                     /product="heme exporter protein CcmD"
                     /protein_id="WP_146581357.1"
                     /transl_table=11
                     /translation="MLGAAGATAAPAAADQGRPAAAAPVRTAPQAPTAATVSEVAKAWR
                     DGPVFVDPDVSDQLSDAQARDLSQEIQDSDKAIFVAVLPATFTDDVDRTMNDLRGDTGI
                     TGLYVLRIGDDLHVRADGSVLSQQATQNLESRFQGTTPADQQLTGLVENATQNMGGRAP
                     NSWSSQDSVSGSTWLGLGIAAVVVGGAAYTLTRRRKIRREQAQREALAKLRVVVDEDIT
                     AFGEELERLDFRPLEPGATDEMRGDYERGLDAYENAKSLMDHARKPEDVREVTKALEDG
                     RFALAVLDARRSGRELPVRRPPCFFDPRHGLSVADVTWAPPGGAPREVPVCAADQARLE
                     RGEAPDIRTVESDEGGRRPYWEAGPAYGPWAGGYFGGGILPGILVGTMLGHMMMSPAYA
                     ADYGSAEGFGGGGAGGGYGGGDVSGSDFDPGDFGGGGGFGDGGGFGGGGGDFGGGF"
     gene            complement(13848..15617)
                     /gene="cimA"
                     /locus_tag="FRZ02_RS10135"
                     /old_locus_tag="FRZ02_10135"
     CDS             complement(13848..15617)
                     /EC_number="2.3.3.21"
                     /GO_function="GO:0043714 - (R)-citramalate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046912 - acyltransferase activity, acyl
                     groups converted into alkyl on transfer [Evidence IEA]"
                     /GO_process="GO:0009097 - isoleucine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019752 - carboxylic acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cimA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470910.1"
                     /locus_tag="FRZ02_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10135"
                     /product="citramalate synthase"
                     /protein_id="WP_261399561.1"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-44, bitscore:
                     149.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQATPEEPAERAPSAATKPQVARDVRGGDGARPAPAGTPASAA
                     SSAAADAAVERPLHIFDTTLRDGAQREGINLSVADKLTIARHLDDFGVGFIEGGWPGAN
                     PRDTEFFARAREEITFRHAQLVAFGATRRAGGSAADDLQVQALLDSGAPVVTLVAKAHD
                     RHVELALRTTLDENLEMVRDTVSHLRAQGRRVFVDCEHFFDGYAANPAYAKAVVRAASE
                     AGADVVVLCDTNGGMLPAQIQAVTATVLADTGARLGIHAQDDTGCAVANTLAAVDAGAT
                     HVQCTANGYGERVGNANLFPVVAALELKYGRTVLPEGALAEMTRISHAIAEVVNLTPST
                     HQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPELVGNRIRMLVSDMAGRASIELKGKE
                     LGIDLGDDRALVGRVVERVKERELAGYSYEAADASFELLLRDELRRGADGAGDAAPSRF
                     FHVESWRAITENRPDGIHANEATVKLWAKGERLLATAEGNGPVNALDRALRVALERIYP
                     ELAKFALRDYKVRILEGRSGTDSTTRVLISTGDGDAEWSTVGVAENVIAASWHALEDAY
                     TYGLLRAGVEPAE"
     gene            complement(15895..17258)
                     /locus_tag="FRZ02_RS10145"
                     /old_locus_tag="FRZ02_10145"
                     /pseudo=""
     CDS             complement(15895..17258)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1074: major
                     facilitator family transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951045.1"
                     /locus_tag="FRZ02_RS10145"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10145"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGRQQWKKIWVGSAGNMVEWFDWFVYASFATYFAGSFFPSGNPTA
                     QLMNTAGIFAVGFFMRPVGGWLLGRVGDRKGRKAALTLTVSLMSASAVLIAIAPTYGVA
                     GYGGAAVLLVARLLQGLSVGGEYAASATYLTEASDADRRGFASSFQYVSMTAGQLLGLG
                     LQIVLQRTMSDDTLHTGAGASRSSSAPSARPSSSTSAATCWRPRSTPSPPRTASSGPTT
                     RAR"
     misc_feature    17290..17304
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.12"
                     /tool="antismash"
     gene            complement(17364..18443)
                     /locus_tag="FRZ02_RS10150"
                     /old_locus_tag="FRZ02_10150"
     CDS             complement(17364..18443)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414969.1"
                     /locus_tag="FRZ02_RS10150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10150"
                     /product="agmatine/peptidylarginine deiminase"
                     /protein_id="WP_018893463.1"
                     /transl_table=11
                     /translation="MPDAPAPSLRGTVPPGFRMPPEWAPHLRTWMAWPGPNPTFATEAA
                     LASAERAWAEVARTVRRFEPVTVLAGPGRAEGARALLGPGIEVVERPLDDAWMRDIGPT
                     FVTRAEDGARAALDWTFNGWGAQEWARWERDARIGGEVAALAGVPAYRTGLVNEGGGLH
                     VDGEGTVLLTETVQLDPDRNPGLTRAEVEAEIHAGLGTSRAVWLPRGLTGDYGRFGTRG
                     HVDIVAAFARPGVVVAHTQPDPAHPDHEVCEEITGVLRAAKDAAGRPLEVVEVPAPTVL
                     EVDGEWADYSYINHYLCNGGVVLCAFDDPRDAEAAALFRRLFPDRTVVPVDARPVFAAG
                     GGIHCITQQEPAPAPAGQG"
     gene            complement(18452..20254)
                     /locus_tag="FRZ02_RS10155"
                     /old_locus_tag="FRZ02_10155"
     CDS             complement(18452..20254)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_process="GO:0043419 - urea catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470907.1"
                     /locus_tag="FRZ02_RS10155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10155"
                     /product="urease subunit alpha"
                     /protein_id="WP_261399562.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 9.6e-47, bitscore:
                     156.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPAGRALPEELTPRPRAFPHLARTPHGRRTAPDEAATASDPYA
                     YAAVHGPRAGDRVRLGDTGLTVRVGADAQRPGDEFLAGFGKTARDGLHLRAAAVRDTCD
                     LVISNVLVIDAVLGIRKVSIGVREGRIHAVGRAGNPDTLDGVDVVVGTGTTIVSGEGLI
                     ATAGAIDTHVHLLSPRVMEASLASGVTTIIGQEFGPVWGVGVNSPWALRHAFAAFDAWP
                     VNIGFLARGSSSHPAPLVEALAEGGACGFKVHEDMGAHTRALDTALRVAEEYDVQVALH
                     SDGLNECLSVEDTLQVLDGRTIHAFHIEGCGGGHVPNVLRMAGVPNVIGSSTNPTLPFG
                     RDAVAEHYGMIVSVHDLKPELPGDAAMARDRIRESTMGAEDVLHDLGAIGITSSDAQGM
                     GRAGETIRRTLQLAAKMKRERGPLDGDGESDDNARVLRYLAKLTVNPARAHGLSHEVGS
                     LEPGKLADIVLWRPEYFGAKPQLVLKSGFPAYGVTGDPNAATDTSEPLVLGPQFGAHGA
                     AAAELSVAFVAGAAVGLGADALPTRRRRVPVRGTRNIGPADLLLNSRTGQVDVDARTGL
                     VTLDGDPVRSGPADSVSLNRLYFL"
     gene            complement(20251..21006)
                     /gene="ureA"
                     /locus_tag="FRZ02_RS10160"
                     /old_locus_tag="FRZ02_10160"
     CDS             complement(20251..21006)
                     /EC_number="3.5.1.5"
                     /GO_function="GO:0009039 - urease activity [Evidence IEA]"
                     /GO_function="GO:0016151 - nickel cation binding [Evidence
                     IEA]"
                     /GO_process="GO:0019627 - urea metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ureA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893464.1"
                     /locus_tag="FRZ02_RS10160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_10160"
                     /product="urease subunit gamma"
                     /protein_id="WP_146580823.1"
                     /transl_table=11
                     /translation="MRLTPTERDRLLIFNAAQLARARQARGLRLNVPEATALISDTVCE
                     AARDGARLAEAVAAGRAVLGPDDVLPGVADVLTEIQVEAVFEDGSRLAVLADPIGGGHT
                     GDQAPGALLPGPPHAEPSPVLTVAVTNTATVPVSVTSHFHFFEANPRLRFDRAAAYGMR
                     LAVPAGSSLRFGPGETREAGLLPIGGARVVTGFAGLVDGPLDAPGARAEALRRAAACGY
                     LGAEAPGTEPAPPGTTPAPPGAPTPETDV"
ORIGIN
        1 ggtggggtgg tcctgctgac aggttgtcgt acaacagagg gggttgaggg acatgaggag
       61 cacagcggag gtctccgtgg cggccgtgat cgaggcggag ccgaaggcgg tctacgagcg
      121 ggtcgccgac gtggcgtcca tggggcggtg gagtccggag tgtgtacgga cggcggcggg
      181 tgtcgggccc gcgccggtgg gcgccgagtt caaggggacc aacaagggcc cgagcggccg
      241 gagctggtcg acgcggtgcc gggtgatggt ggcccgctcc ggcgagcggt tcaccttccg
      301 ggtgcggttc tgggggatgc cggtggccac ctgggactac cgcttccgcc cggtcgggga
      361 cggcaccgcg accgaggtga ccgagacggc cgtggaccag cggaaccggc tcctgtggtt
      421 cctcggttcg gcggtcagcg gcgtctggga ccgcagcgcg cacaacgccg agaccatgcg
      481 ggagaccctg gagcggctgc gcgagacgct ggaggcggag cgccgggccg gctgagcccc
      541 tcccgggcac cggccgtcgc cctcccgcgg gcgtccgggg gcggcggaac gtacgcctgc
      601 ctcccccggg ccttcccgta cggccacgcg ccccgcggct gacggcccgt ccggcgttgt
      661 cggtggcgtg tggtgggatc ggacacatga gcgatcacgg aacgacgggg accgccgggg
      721 acgaagcgcg cgcccgggcg gtgcgggacg cctgggcgcg catcgacgcg tggatgcgcg
      781 cccacgcccc ggactcctac gaggtgctgg cgccgcccgc cgacccggcg gcggtcgagg
      841 cggcccaggc cgagatgggg gtgggtttcc cggcggacct cctcgcctcc ctcgcctgcc
      901 acgacggcct gcgccactgg gacaactgcc tgccgctgcg cccgcccgag cccgtcgcca
      961 ggatcgtcga ccactggcag atgtgcgtcg agatcgacga ggacaaccgc gccgacgagg
     1021 acgagccgga gcccgagggc gaggagccct ggtggcaccc ccagtggatc ccctgggccc
     1081 agagcgacgg cgacgcccag atcatcgaca tgcgcccggg ccccgcccag ggccgcctcg
     1141 gcatggccta ccacgacgac tgcggcgtct tcaccggcgg ctggccgtcc ctggcggcat
     1201 acctgaccga ggtcgccgac gtcctggaga agggcggggc cgtgggcgga acgtgggccc
     1261 ccttcctgac gaccgagggc gaactgtggt ggtccctcaa gggcgagacc cagctcaacg
     1321 gagagccact ggtaccggct ccggcgcctg cggccggtac ctgacgcccc gccgggccgg
     1381 ggctcaccgc accggcccga tcgggtgacg cggcaccgcc gggcgcggcg tttatgttga
     1441 gcgcatgaca cagggggcgg actcggcagt acgggcgcgg acggcggagg ggcgggcgaa
     1501 gagcgccggt ggcgggctgg cccggtcgtc gctgctgatg gcggtcggga cggtggtgtc
     1561 ccgggcgacg gggctgatcc ggcaggtgtt gcaggcggcg gctctgggga cggggctgct
     1621 ggccagtacg tacaacacgg cgaacacggt gccgaccagt ctctacacgc tgctgatcgg
     1681 cggcgcgctc aacgccgtcc tggtgcccca gctcgtacgg gccagggcga cggagccgga
     1741 cggcgggcgg gcctacgaac agcggctggt gacgctcgtc gtctgtgtgc tcgggatggg
     1801 gacggcgctg gcggtgtggg cggcgccgga gatcgtcggc ctgtacatgc gggacacgcc
     1861 agggagccat gaggcgttcg aactgacggt gacgttcgcc cggttcctgc tgccgcagat
     1921 cttcttctac ggcctcttcg gcatctacgg gcaggtcctc aacgcccggg agaagttcgg
     1981 ggcgatgatg tggaccccgg tgctcaacaa cgtcgtcctg gtggcgatgt tcgcggcgta
     2041 cctcgggctg atggtggcgc ccggccgggt ggaggacatc accgcggatc aggtgcggct
     2101 gctcgggatc gggacgacgg ccggggtcgc gctccaggcg ctggcgctgg tgccgttcgc
     2161 gcgggccgcg gggttccggt tccggccgcg gttcgactgg cggggcaccg gactgggccg
     2221 gagtgtgcac gcggcgaagt ggacgctgtt gttcgtgctg gccaaccagg tggcgctgac
     2281 cgtggtcacc cacttcgcca acgccgccga ccaggaactc cccgaggccg gcgcgggcta
     2341 caccgcctac atgtacgcgc agaccatctg gctgctgccc cagtcgatcg tcaccgtctc
     2401 cctggtgacg gcactgctgc cccgcatgag ccgggccgtc gcggacggcc gtgtcgggga
     2461 cctgcgcgcc gacctgacgc gcgggctacg gatcagcggc gtcgtcatcg tgccgaccgc
     2521 cttcctcttc ctcgccctcg gcccgcagat cgcggccctg ctcttcgccc acggcgcggc
     2581 ggacgccgcc tcggtccgcc cgctcggcca gatgctccag gcgttcgggc cgggcctcat
     2641 cgcgttctcc gcccagtacc tgctgctgcg cggtttctac gcgtacgagg acacccgtac
     2701 gccgttcttc atggcggcct ggatcgcggg cgtcgacatc gccctggcga gcgcctgcca
     2761 tctgctgctg cccgcgcgct gggccgtggt cggcatggcc ggggcgtaca ccctctccta
     2821 cctcgccgga ctcgccctca ccgcccgcct gctgcgccgc aggctcggcg ggcggatcgg
     2881 caccggagga ctgggccgcg cctacgggaa ggtgctctgc gcggcggttc ccgcagccgg
     2941 actgggctgg gccgccgcgc gggcgctctc cgggcccggc ggcccgggtg cggccgggac
     3001 gtggtccacc gccgtggccc tggcctccgg tgtcctctcc accgccgtcg cctacctcct
     3061 cctcgcccgc ctgctcaagg tcgaggaggt acgccggctg ccgggtctgc gatgacgggc
     3121 gggcccggtt ccccggcccg cccgtccgga ctaccgcagg gcgacgtggt cgccgctcga
     3181 cgacctggct ccggaggtcg agttgccgta gtaggtccag cgccacgtcc cggactcggt
     3241 ggccttcacc gtggtcttga gcacgccctt gctgccggac gtcaccttct tgaccgtctt
     3301 gtacgaggag gctccggagg gcttgaactg gaggctgacg gtgcgtccgg cgtagccctg
     3361 gtaagtgtgc gtgtcccagt tggcgcgggt gacggccccc ttcacggtga gggtcttgcc
     3421 cttggtcacc ggttccggcg tggcgttgac ggtgaggcgg gtggcgcgct tgacctggag
     3481 cggcaggttc tcgtcgtcca tgtcgtaggt gccgtcggcc aaccacatct ccgcgcgggt
     3541 ccgccaggtg ccggtgtccc cgttggtgac gtccttgtgc cgcgggtcta tgtggatcga
     3601 caggtcgaag tcgtagatcc ccttcgcctt gtccaccacc ttggggtcgc tggtgtggat
     3661 gctgctccag agcgcgtcac cgacaccggc gggggtgttg cggtaggggt acacgacggg
     3721 gccgccatcg aatttgcgcc gcgtcgtcat ccgtacggaa gcgggtatct caacgatctc
     3781 cttcaccccg agaacgatcg gctggccgtt gttcaccttg acccgggtga aggagacccc
     3841 gccctctgcc gccccggccg gcaccgccgc cagccccgtg aacacggccg ccgcgccgcc
     3901 ggccaccgcc gttctccaca gcgtcttccg cgtcatcgaa cccgccctct ccccacagcg
     3961 tgcacgggcg cgcaggcgcc ccggccggag tctcgtcctc tcggctgatg gtgggacagc
     4021 ggagggcggt gcgcggttgt gcgcacggtg ggacacgttt tgatcactgt ggcggcagtg
     4081 ccggggcggc gctgtcgctg ctgggtggtg ggatgggccg tatgagtgac gacgaggcgg
     4141 ggcaggccgg ggccgaggcg gtgcgggcgg cgtgggggcg gatcgacgcc tggttgcgga
     4201 agtgggggcc ggattcgtac gcgcgcctgg cgccgcccgc cgagccgggg gcggtggcgg
     4261 cggcggaggc tgccctgcgc atgcggttcc cggcggagtt gcgggcctcg ttggggtgtc
     4321 acgacggggt cgggggcgag ggggtgctgc cggtgaagcc gccgttgtcg gccgccggga
     4381 tcgtgcggta ctggacgagg tggatggagc tgaccgagga ggagcgggag ttcggggacc
     4441 cggaggagga gggggaaccg tcctggcacc cccggtggat tccgtgggcg gagagtgacg
     4501 gtgacgccca gatcatcgac gggagggacg ggccggggtt cgggcggctc ggcatgaagt
     4561 accacgacga ggaggggagt ttcggcgacg acgccccgtc gctcgcggcc tacctcaccg
     4621 aggtcgcgga cgcgctggag aacgggcggt cggtcggtgg gcgggtgccg tatgtggggg
     4681 tgagcggaga gatgtggtgg gccgaggctc ccgccgcccc ttccggcggc gggtgagccg
     4741 cgctcgccgt accgctgcgg tcaccggtcc tcctcccagg tcgcggtttc ggggtcgatg
     4801 ccgtgggccc tcgcggcggc gtcgacgagt tggcggaacc aggtggcgag gccggggcgg
     4861 atggcgtcgt ggtgggcggc gaagcccggg tcgctctcgt acatgcggcc gaggcagacc
     4921 tgcatctgcc gggagagggg gaagtaggac gcgaagacct cgcggtggcg ttcgacgagg
     4981 tggttcgcct ccggactgcc cggggtgaca ccggcgtcca tcgcctcgcc gagggcgcgt
     5041 tcgagccggg cggtgtcgtc ggcgacggcc tgccactcct ccggggtgcg ggaggcggag
     5101 cgttcggcgt actgccgcca ttgcgtcgtg tccccgtagc gctgacgggc ctggaccggc
     5161 ccgtcggggc tccatccggg gccgaagatc gcggcctgtt gctcggcggt cagcagcagg
     5221 ccgtgttcgt gggcgtcgat catccggtcg agtccggcgg cgagttgccg gaggcggtcg
     5281 atccgggcgg cgatctgggc gcgttgcgcg cgcagagcgg ccggtacgtc cgtggccgag
     5341 tcgtcgagga cggaccggat cttgtccagg ccgaggccga gttcgcggta gacgacgatg
     5401 cggtgcaggc gttccaggtc gggggcggtg tagagccggt atccggcggg cgtgcgcagg
     5461 gagggccggg ccaggccgat ctcgtcccag tggtggagcg cgcggaccgt cacgtccagg
     5521 cgcgccgaga cctgaccgac ggtcaggccc tcggcgtccg tggtgtcagg catgccgctc
     5581 attgtcgccc ggggtcccgc ccggcggggt gatgccgatg gcctccaggt tgcgtgcttc
     5641 ctgggtgtcc gggtcgaagg gcttcgcggc ggtgaagacg atgcgcgcgt tctcgggggt
     5701 gacgacttcc acgtcacggg tgttccaggg cgtgtcccgc ggcccctcga ccgcgtccgg
     5761 gcgcagcgcc cggcatgccg cgacgaggga gtcgacctcg ctgagcacgc cggagaagct
     5821 gaagctcatc gccggcggct ggtccggaac gctctccgcc gccacgagca gtacgtcctg
     5881 gaacgcccat cggcgcagat gaacgagggt tcccgggatg ctgaacagct cgaagaagcc
     5941 gagccccctc gtccagaact ccaccgacgc cgccagatcg gtcgtcggga tgttcacgaa
     6001 ggcgggcatg ccgtagatgc cgcggaacgg ctccggcgcg accgcgtcgg gcccgggggc
     6061 gggcacgggg ctgatctcga acgcgttgta gtaggtgtgg tcgctcatgt gccccagcct
     6121 cgggcctcac gcgacgtgag ggtcaagccg gatgcgtgcg ccctccgggc ctggcggaaa
     6181 agaccgcgca tccggaacac gcccgtgcca ggctgaccgc atgacgacct accaccgaaa
     6241 ggcccgtgcc gcgtaagccg ccgggaaggg tgcggaccgg actcccccgc ccgcgcaggc
     6301 cctacgagaa gtcgcccgtg atcgacgggc tgccggccgg gacgctcgcc gagctggccc
     6361 ggctggagcg cacgcggaac tacctctggc ccggggccgt ttccgaggcc ctgcgcacct
     6421 gggccgcgca tgtgcggctc ccgcgcggcc gcacctggcc ccgccagcag gacggcccct
     6481 gttactgctg cccggacccc cgggagtccc gggagctgct cgaccgggtc gcccgcgccc
     6541 tgtcgcggcg cgcagcgcgc gagctgcggc gcgtgctggc cgggcacgac cagctgtggg
     6601 acccggcgcc ccggccgtac cggggtgagg gcccgtggtg aggcggggcc tcaccgttca
     6661 ctccggtgcg cacgcccgca cgacggaggc gatcacgtcg tccaggcccc ggtccggggt
     6721 ctgcggcagc ggggcaccgc cggcggcgag gccgatgtag ccgtgcagag gggccaggac
     6781 ggtgagggcg acgcggtccg gcgggccctc gcggacctcg ccccggctct ggccgtcccg
     6841 aatgagggcg agcccctgtt cggcccagcg gcgggcggcg tcgcggagcc cttccgacgc
     6901 ctcggggctg tgcttggccg agaacatcag gctgagcagg gccggatcgg agagggagaa
     6961 gccgacgtag gcgcgggcca tggcgtccag gcgttcggcg aaggggcgcg cctcgccgcc
     7021 ccgagcggcg accagggagt cgatgaggcg ctcgaagccg tcgagggcga gtgcgtcgag
     7081 cagcacctgc ttggaggcga agtgccggcg cggagcgccc ggactcacgc cgacgtcgcg
     7141 ggccagctcg cgcagcgaga gggcccccac ccctccctca cgcagggtct ccccggcccg
     7201 ggcgagcagg gcggcgcgca ggtctccgtg gtggtagggg cgcttgtcca tgggctcagc
     7261 gtaagtccgg cgacgcgctg atgtagtcgt tgaatacatt gtacccatcg catacattgg
     7321 ccaggcgtgc ccggacaccc gagagcgcgc cgcaccccgc tggaggaacc atgtcccgca
     7381 agcccgtcga cctcaccctc cccgatctct ccggccggcg cgccgtggtc accggcgcca
     7441 gcgacggcct cggtctgggg ctcgcggccc ggctcgccca ggcgggagcc gaggtgatcc
     7501 tgcccgtacg caatcaggag aaggggcggg cggcgctgga ggagatccgg cggggagcgc
     7561 ccggggccga ggtgtcgctg cgcgagctgg acctgtcctc cctcgcctcc gtcgccgcgc
     7621 tcggcgaggc cctgcgcgcg gaggaccgcc cggtccacct cctcgtcaac aacgcgggcg
     7681 tcatgacccc gcccgagcgc cgcaccaccg ccgacggctt cgagctgcag ttcggcacca
     7741 accacctcgg ccacttcgcc ctcaccgccc atctgctgcc cctgctgcgc gccgggcggg
     7801 cccgcgtcac ctcgcagatc agcgtggccg ccgaccgcaa cgcgatcaac tgggaggacc
     7861 ccaactggga gtcctcctac aacggcatga aggcgtacag ccactccaag atcgcgttcg
     7921 gcctcttcgg cctcgaactg gagcggcgcg cacgggcgca cgactggggc ctcacgagca
     7981 acctctcgca ccccggcgtc gccccgacca gcctcctcgc cgcccgcccc gaggtcggcc
     8041 gcgccaagga caccaccggg cggcggttca tcaaggcgct ctccgcccgg ggcatcctcc
     8101 tgggcaccgt cgagagcgcg aagttccccg cgctgtacgc ggccacggcg cccgaggccg
     8161 ggggcggcag gctgtacggc cccagcggcc ccggccacct cggcggcccc ccggccgagc
     8221 agaagctcta ctcccgcctg cgctcgatcg aggacgcccg ccgcgtctgg cgcctgtcgg
     8281 aggagctgac cggcgtcacc ttcccgggca actgacgccc acgggacgga aggagcacca
     8341 gacgatcttg cccgggttgc gctcccccac cccccagtcg tcggcgaggg cggagacgag
     8401 gagcaggccc cggccggact cggcctcgtc gccgggggcg cgggtcgccg ggtgcccgtc
     8461 gccactgtcg tggacctcga cgcgtacgcc gccgtcgtcg gcccggagca cgaagagccg
     8521 gaagccgcgc cccggcggga cgccgtggag cagggcgttg gtggccagtt cgctcacgca
     8581 gagcaagacg tcgtcgcggg gcacgcgggc gtcccactcg ttcagcacgg cggcggtgaa
     8641 gtccctggct gcggggacgg atcggcgctc gcggcggtag aagcgctcgc agtgcgcggg
     8701 gagtccggtt tcggttttca ccctcctacg gtcacccaac gtcactagcc ttgtgcaggg
     8761 cgtcgacccg tacaaatccg ttgtacgggt cgtgtcgggt gcgcgacggg gcgcgtcggg
     8821 agatggagta cgcatgcagc agcgaaagaa gtccagcaag aaggtcacgt cgtgggaagt
     8881 gctcggcaaa caactggccg agttccggcg ggtggcgggg ctgacccagg ggcagctggc
     8941 tgagcgcgcc caggtgggcg aggacaccgt ctcctcggtc gagcagggca ggcggcggct
     9001 acaggcagac ttggccgaac gcctggacac aatccttgag acaaaacagg cgctgagtac
     9061 agcggtgtcg acgatcccga cgcacgagcg attccccctg ttcgtccagg acttcatcga
     9121 acacgagcaa cgggccatca ccctgctctc gtacgagaac cacctcatcc ccgggcttct
     9181 gcaaacgccg gagtatgcgc gagcggtatt caacaactcc tatccgccaa ttcctgccca
     9241 agaggtggag gaatccgcgc aagcgcgtat cgacaggcag caaatactgt cgagcggcaa
     9301 gcctccgatg atgagcttca tcatcgagga gagcgtgctc caaaggcact tgggcgaccc
     9361 ggaagccatg agacgacaga tcgagcacct gcgcgcctgt gccgatctac ccttcctgag
     9421 cttgcagatc atgcctaccg acactgatgc tcacgcaggt ttggcgggcc ctctcgtgtt
     9481 gctggagacg cccgagcacg accaccttgc gtacatcgaa ggccagtaca agggcgtcat
     9541 ggtggaggac ccggacgagg tcagtatgtt ccagcagaag tatgggatgc tgcgggcgca
     9601 ggccctcaca ccccataaga cgaaggccct gctggacaca ctgcttggag tgacatgacc
     9661 ggcgcccctt cccgaaacga acccctctcc tggttcaagt cgagctacag cagcgacacg
     9721 ggcggcaact gcatcgaggt cgcctacaac tggcgcaagt ccagccacag cagcgacgcg
     9781 ggcggcgcct gcgtagaggt cgccgcccac cccaccaccg tccacgtccg cgactccaag
     9841 gtcccggcgg gacccaccct cgacgtgacc cccgccgcct gggcggcgtt cgtacacgcg
     9901 accgccggtc cactcgtatg acaacaccgc cgtccggctg acgggtcggg cgggcgggta
     9961 gtgatcgggc cgccggtatc accgtgtgga aggctcgacc gtgacacagc cctttgtcct
    10021 gcccgatttc tacgtgccgt atccggcgcg gctcaaccct catctcgaag aggcgcgcgc
    10081 ccatgcccgg gtctgggcgg acgagatggg gatgctggag gggtcgggga tctgggacct
    10141 ggccgacctg gaggcccacg actacgcgtt gctctgcgcg tacacgcatc cggactgcga
    10201 cggtccggcg ctgtcgctgg tgaccgactg gtatgtgtgg gtcttcttct tcgacgacca
    10261 tttcctggag ctgttcaagc ggacgcagga ccgtgagggc gcgaaggcgt acctggagcg
    10321 gctgccggcg ttcatgccga tggacctggc cgacgggttc ccggagccgg agaatccggt
    10381 ggaggcgggg cttgccgacc tctgggcgcg gacggttccg gccatgtcgg aggactggcg
    10441 ccgccgcttc gccctctcca cggagaacct gctcaacgag tcgatgtggg agctctccaa
    10501 catcaacgcg ggccgcgtct ccaacccgct ggagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgcgccc tggtcggcgg ggctcatcga gtacgcggcg caggccgagg tgccggaggc
    10621 ggtggcgtac tcgcggcccc tgcgcgtgct gaccgacgcc ttctcggacg gcgtccacct
    10681 gcgcaacgac ctcttctcgt accagcggga ggtcgaggag gagggcgagc tgagcaacgg
    10741 cgtcctcgta ctggaacggt tcctggagtg caccacgcag gaggcggccg aggccgtcaa
    10801 cgacctgctg acctcacgcc tccagcagtt cgagaacacc gcgctgaccg aactggggcc
    10861 gctcttcgcc gacaaggggc tgaatccggc cgagtccgcc tcggtgctgg cgtacgtgaa
    10921 ggggctccag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccggtacat
    10981 gaacgagggc gcggtcgacg gggaggcggc gccgccgact ccgggcgggt cgccgggggc
    11041 gctggcggcg gcgctgctgg gcgggacgct tggcacgtcg gcactggacg tacgggcgtt
    11101 cttcgggcgt ccggcgcggc agcgggcgcg cagcttctcg cacgtgccgt accagaggac
    11161 gggggcctcg ctgctgccgg acttcaagct cccgttcccg acgcggctct ccccggcgct
    11221 ggagcagtcc cgggtggaca cggtcgagtg ggcgcaccgg atggggctgc tcgtgccgca
    11281 gcccggggtg cccgggtcgg acgtgtggga cgaggaggcg ctggccggct acgacttccc
    11341 gctctgcgcg gccgggctcc atccggaagc cgacctggag gaactgaacc tcgcctcgca
    11401 gtggctgacc tggggcacct acggcgacga ctattacccg gcggtcttcg gccgtgcccg
    11461 gaacttcgcc ggggccaagc tctgcaccga ccggctgcgg gacttcatgc cggtcgagca
    11521 gccctcggcg gggccggtgc cgaccagcgc gctggaacgc tcactggccg acctgtgggt
    11581 gcggaccgcc tccgcgatgc cggagaaggc ccgccgcgcg ttccggcaga ccatcgaggt
    11641 gatgctggac agctgggtct gggagctgga caaccaggcc atcggccgca tccccgaccc
    11701 gatcgactac atggagatgc gccgcgccac cttcggctcc gacctgacga tgagcctgtg
    11761 ccgcctgcgc cacggcaaca tcgtccccga ggaggtgtac cgctcgggca ccatccaggc
    11821 gatggagaag gccgtctccg actacggcgc gctgatcaac gacgtcttct cgtaccagaa
    11881 ggaagtggag ttcgagggcg agatccacaa cgccgtcctc gtcacccaga acttcttcga
    11941 ctgcgactac ccgaccggcc tggcgtacgt ggacgcgctg atgaacgcgc ggctggaaca
    12001 gttcgaacac atcgtggccc acgaactccc cgtgctgtac gaggatttcc agctggacgg
    12061 ggcggccagg aaggtgctcg acgggtacgt gcggcagctg gagaactggc tgtcggccat
    12121 cctgacctgg caccggggct gcaagcggta caaggaggag gacctgagcc accactcccc
    12181 cggcgtgcgg cgggtgatcg aggccgcgcc gcgcgggatc gggccgaacg ggctcggcgc
    12241 ctcctcgctg ggcacggccg ccgcccgggt gttcgccggg gggtgacggg agcgggccgg
    12301 ggcgggcggc tcgggcgggg tcagaagccc ccgccgaagt cgccgcctcc gcccccgaat
    12361 ccgccgccgt cgccgaagcc gcccccgccg ccgaagtcac cggggtcgaa gtcggagccg
    12421 gagacgtcgc cgcccccgta gccgccgccc gcgccgccgc cgccgaagcc ttcggccgag
    12481 ccgtagtcgg cggcgtaggc ggggctcatc atcatgtggc cgagcatggt gccgacgagg
    12541 atgccgggga ggatgccgcc gccgaagtag ccgcccgccc aggggccgta cgccgggccg
    12601 gcctcccagt acgggcgccg gccgccctcg tcggactcga cggtgcggat gtcgggggcc
    12661 tcgccgcgct ccagccgggc ctggtcggcg gcgcagacgg gcacctcgcg gggcgcgccg
    12721 ccgggcgggg cccaggtgac gtcggcgacc gagaggccgt ggcgcgggtc gaagaagcac
    12781 ggcgggcggc gcaccggcag ctcacggccg ctgcggcggg cgtcgagcac ggcgagcgcg
    12841 aaccggccgt cctccagcgc cttggtcacc tcgcgcacgt cctcgggctt ccgcgcgtgg
    12901 tccatgaggg acttggcgtt ctcgtaggcg tcgaggccgc gctcgtagtc gccgcgcatc
    12961 tcgtcggtgg cgcccggttc caggggccgg aagtcgagcc gctccagctc ctcgccgaag
    13021 gcggtgatgt cctcgtccac cacgacccgc agcttggcca gcgcctcccg ctgggcctgc
    13081 tcgcgccgga tcttgcgccg ccgggtcagc gtgtaggcgg cgccgcccac gaccacggcg
    13141 gcgatgccga ggccgagcca ggtcgagccg gagacgctgt cctgggagga ccaggagttg
    13201 ggggcgcggc cgcccatgtt ctgggtggcg ttctcgacga ggccggtgag ctgctggtcg
    13261 gccggggtgg tgccctggaa gcgggattcg aggttctgcg tggcctgctg ggagaggacc
    13321 gacccgtcgg cgcggacgtg caggtcgtcg ccgatgcgca ggacgtacag accggtgatg
    13381 ccggtgtcgc cgcgcaggtc gttcatggtc cggtcgacgt cgtccgtgaa ggtcgccggg
    13441 aggaccgcga cgaagatcgc cttgtcgctg tcctggatct cctgggagag gtcgcgcgcc
    13501 tgggcgtcgg agagctggtc cgagacgtcc gggtccacga agacggggcc gtcgcgccac
    13561 gccttggcga cctcggagac ggtcgcggcg gtaggggcct gcggagccgt ccgcacgggt
    13621 gccgcggcgg cgggcctgcc ctggtcggcg gcggcgggcg cggccgtcgc tccggcggcg
    13681 cccagcacga gaagaggccc ggacgcgatg agagcgcccc ggcgtatgga ctggcggact
    13741 acggctcgcc tcatacctcc acgctaaccc gggtcgccgc gaaacgcccc ggacgggcgg
    13801 cggggcgggt acggggcccc gccgccccgg gcgtacgcgc ttcgggccta ctcggcgggc
    13861 tcgaccccgg cgcggagcag gccgtaggtg taggcgtcct ccagggcgtg ccaggaggcg
    13921 gcgatgacgt tctcggcgac gccgaccgtc gaccactccg cgtcgccgtc gccggtggag
    13981 atcaggacgc gggtggtgga gtcggtgccg gagcggcctt ccaggatgcg gaccttgtag
    14041 tcccgcaggg cgaacttggc cagctccggg tagatccgct ccagggcgac gcgcagggcg
    14101 cggtccaggg cgttgacggg gccgttgccc tcggcggtgg cgaggaggcg ttcgcccttg
    14161 gcccagagct tcacggtggc ctcgttggcg tggatgccgt cggggcggtt ctcggtgatc
    14221 gcccgccacg actcgacgtg gaagaagcgg gacggggccg cgtcgcccgc gccgtcggca
    14281 ccgcgccgca gctcgtcacg gagcagcagt tcgaaggagg cgtcggcggc ctcgtaggag
    14341 tacccggcca gctcgcgttc cttgacgcgc tccacgacgc gcccgaccag ggcgcggtcg
    14401 tcgccgaggt cgatgcccag ctccttgccc ttcagctcga tggaggcgcg gcctgccatg
    14461 tcggagacga gcatgcggat gcggttgccg accagctccg ggtcgatgtg ctggtacagg
    14521 tcggggtcga ccttgatcgc ggaggcgtgc agtccggcct tgtgcgcgaa ggcggagacg
    14581 ccgacgtagg gctggtgggt ggagggggtg aggttgacga cctcggcgat ggcgtgcgag
    14641 atgcgggtca tctcggcgag cgcgccctcg gggagcacgg tgcggccgta cttcagctcc
    14701 agggcggcga cgaccgggaa gaggttggcg ttgccgacgc gctcgccgta gccgttggcg
    14761 gtgcactgga cgtgggtggc gcccgcgtcg acggcggcga gggtgttggc gacggcgcag
    14821 ccggtgtcgt cctgggcgtg gatgccgagg cgggcgccgg tgtcggcgag gacggtggcg
    14881 gtgacggcct ggatctgcgc gggcagcatg ccgccgttgg tgtcgcagag gacgacgacg
    14941 tcggcgccgg cctcgctcgc ggcgcggacg acggccttgg cgtaggccgg gttggcggcg
    15001 tacccgtcga agaagtgctc gcagtcgacg aagacccggc ggccctgggc gcgcaggtgg
    15061 gagacggtgt cgcggaccat ctccaggttc tcgtcgaggg tggtgcgcag ggccagctcg
    15121 acgtggcggt cgtgggcctt ggcgaccagg gtgacgaccg gggcgccgga gtcgaggagg
    15181 gcctggacct ggaggtcgtc ggcggcgctg ccgcccgcgc ggcgggtggc gccgaaggcg
    15241 acgagctgcg cgtggcggaa ggtgatctcc tcgcgggcgc gggcgaagaa ctcggtgtcg
    15301 cgcgggttgg cgccgggcca gccgccctcg atgaagccca ccccgaagtc gtccaggtgc
    15361 cgggcgatgg tcagcttgtc ggcgacgctg aggttgatgc cctcacgctg cgcgccgtcg
    15421 cggagcgtgg tgtcgaagat gtgcaggggg cgctcgacgg cggcgtccgc ggcggcggag
    15481 gacgccgcgg aggcgggggt tccggcgggc gcggggcgcg ccccgtcgcc gccccgtacg
    15541 tcgcgtgcga cctgcggttt cgtcgcggcc gacggggcgc gctcagcggg ttcctcgggg
    15601 gtggcctggc tggtcatgcg gtggtgactc ctgtcgggtg agtggctccg gaatgcttgg
    15661 ctccacttgc ccccgtcctc tcgtgcgcct cgccgcggcc cggtcggggc cgacaaacga
    15721 aaagacccct cgcgggtgcg agaggtctgc gcgcgggtct ggggcacggt ggccgcgtcg
    15781 cacgtggtgg tgcggggcgg tcactgcgga ccggcgcgcc tgctgccgat aatcatggcg
    15841 aacgtgggca cgggggcagt ctcccacaga gaggcccccg tgccacgagg tgtctcagga
    15901 tgcgagcggg gcgcccgttt tcgcgtgccc ggaggccggg gaggcaggcc cggcctcggc
    15961 ggagggcgga cccgtctcgg cgccgacccg gttgaggtcg atgtcccggg tctccttcat
    16021 cgccaggtag acgacgagcg agacggcggc gcaccccgcc acgtaccagt agtagcccga
    16081 ctccgtcccg ccgttcttga accagagcgc gacgtactcg gcggtgccgc cgaagagggc
    16141 gttgccgagg gcgtagggca gggcgacgcc cagcgcgcgg atgccggtgg ggaagagttc
    16201 ggccttcacg caggcgttga tcgacgtgta gccggtgatg atgagcagcg cgaggagcga
    16261 gaggccgagc gccggccaga acgacccggc gtgctggagc agcgtcatga tcggcacggt
    16321 caggaaggtc gagccgacgg cgaaggtgat cagcagcggg cggcggccga tccggtcgga
    16381 gagcatcccg gcgagcggct ggacgcacat gaagacgaag agcgcgcaga acgagacgag
    16441 cgtcgccgtc tccttgggca gcccggcaga gttcgacagg tacttggtca gataggtcgt
    16501 gtacgtgtag tacgcgacgg tgccgcccat cgtcagcgcc acgaccagga aagcctggcg
    16561 ccggtgctgc cacagcgcct tcatcgtgcc cttgtcgtcg gcccgctcga cgccgtcctc
    16621 ggaggactcg gcgtagacct cggtctccag catgttgcgg cggaggtaga agacgacggc
    16681 cgcgccgagg gcgccgatga tgaacgggat gcgccagccc cagtgtgcag ggtgtcgtcc
    16741 gacatggtcc gctggagcac gatctgcagg ccgaggccga ggagctggcc cgcggtcatc
    16801 gagacgtact ggaagctgga ggcgaagccg cgccggtcgg cgtcggacgc ctcggtcagg
    16861 taggtcgcgc tggccgcgta ctcgccgccg accgagaggc cctggagcag gcgggcgacc
    16921 aggaggacgg cggcgccgcc gtagccggcc acaccgtagg tcggggcgat cgcgatcagc
    16981 acggcggagg ccgacatcag cgagacggtg agggtcagcg ccgccttgcg gcccttgcgg
    17041 tcaccgaccc ggccgagcag ccagccgccg accggccgca tgaagaagcc gacggcgaag
    17101 atgccggcgg tgttcatgag ctgggcggtc gggttgccgc tggggaagaa ggaacccgcg
    17161 aagtacgtgg cgaagctcgc gtacacgaac cagtcgaacc actcgaccat gttgccggcc
    17221 gagccgaccc agattttctt ccactgctgt cgtcccatgc tcggcacgct gccggaatga
    17281 tccattccga cacaaggtgt atggggcaac gatcgggatt acttgagtgc tttgcgttcg
    17341 tggggacggg gacgccgggc cgctcagccc tgtccggccg gggccggcgc cggttcctgc
    17401 tgggtgatgc agtggatgcc gccgccggcc gcgaagaccg ggcgggcgtc gacggggacg
    17461 acggtgcggt ccgggaagag gcggcggaag agcgcggcgg cctcggcgtc gcgcgggtcg
    17521 tcgaaggcgc agaggacaac cccgccgttg cacaggtagt ggttgatgta cgagtagtcg
    17581 gcccactccc cgtccacctc cagcacggtg ggcgcgggca cctcgaccac ctccagcggg
    17641 cggcccgccg cgtccttggc ggcgcgcagc acgccggtga tctcctcgca gacctcatgg
    17701 tcggggtggg ccgggtcggg ctgggtgtgc gccacgacca cgccgggccg ggcgaacgcc
    17761 gcgacgatgt cgacgtggcc gcgcgtcccg aaccgcccgt agtcaccggt cagcccgcgc
    17821 ggcagccaca ccgcccggct ggtaccgagc cccgcgtgga tctcggcctc cacctcggcg
    17881 cgggtcaggc cggggttgcg gtccgggtcg agctggacgg tctcggtgag cagcacggtg
    17941 ccctccccgt cgacgtgcag cccacccccc tcgttgacca gccccgtccg gtacgccggg
    18001 accccggcca gcgcggcgac ctcgccgccg atcctcgcgt cccgctccca gcgggcccac
    18061 tcctgcgcgc cccagccgtt gaacgtccag tcgagcgcgg cccgggcgcc gtcctccgcg
    18121 cgggtgacga aggtggggcc gatgtccctc atccaggcgt cgtccagcgg gcgttcgacc
    18181 acctcgatgc cgggcccgag gagcgcgcgg gcgccttcgg cgcggccggg cccggcgagc
    18241 acggtgaccg gttcgaagcg gcgtacggtg cgggccacct cggcccaggc gcgttcggcc
    18301 gaggcgagtg cggcctcggt ggcgaaggtc gggttggggc cgggccaggc catccaggtg
    18361 cgcaggtgcg gggcccactc gggcggcatc cggaagcccg gcgggacggt gccgcgcagg
    18421 gacggggcgg gggcgtcggg catggcggtc ctcagaggaa gtagaggcgg ttgaggctga
    18481 cggagtcggc ggggccggag cggaccgggt cgccgtcgag ggtgaccagg ccggtgcggg
    18541 cgtccacgtc gacctggccg gtgcgggagt tgaggaggag gtcggcgggg ccgatgttcc
    18601 gggtgcctcg gacggggacg cggcgcctgc gggtgggcag ggcgtcggcg ccgaggccca
    18661 cggcggcgcc cgcgacgaag gcgacggaca gctcggcggc ggccgccccg tgcgcgccga
    18721 actgggggcc gaggacgagc ggttcgctgg tgtcggtggc ggcgttgggg tcgccggtga
    18781 cgccgtaggc ggggaagccg gacttcagga ccagctgggg cttggcgccg aagtactcgg
    18841 ggcgccacag cacgatgtcc gccagtttgc cgggctccag cgagccgacc tcgtgggaga
    18901 ggccgtgcgc gcgggccggg ttgacggtca gtttggcgag gtagcgcagg acgcgggcgt
    18961 tgtcgtcgct ctcgccgtcg ccgtcgagcg ggccgcgttc gcgcttcatc ttggcggcga
    19021 gctggagggt gcggcggatc gtctcgccgg cccggcccat cccctgcgcg tcggaggagg
    19081 tgatgccgat ggcgcccagg tcgtgcagga cgtcctcggc gcccatcgtc gactcgcgga
    19141 tgcggtcgcg ggccatcgcc gcgtcgccgg gcagctcggg cttgaggtcg tggaccgaga
    19201 cgatcatgcc gtagtgctcg gcgacggcgt cccggccgaa gggcaaagtg gggttggtgg
    19261 aggagccgat gacgttcggc acgcccgcca tgcgcagcac gttggggacg tggccgccgc
    19321 cgcatccctc gatgtggaag gcgtggatgg tgcgcccgtc gagcacctgg agggtgtcct
    19381 cgacggagag gcattcgttg aggccgtcgc tgtgcagggc cacctgcacg tcgtactcct
    19441 cggcgacgcg cagcgcggtg tccagcgccc gggtgtgcgc ccccatgtcc tcgtgcacct
    19501 tgaacccgca cgccccgccc tccgccagcg cctcgaccag cggcgccggg tgcgaggagg
    19561 aaccgcgggc gaggaaaccg atgttgacgg gccaggcgtc gaaggcggcg aaggcgtgac
    19621 gcagggccca cggcgagttg acgccgacgc cccagacggg gccgaactcc tggccgatga
    19681 tcgtggtcac gccggaggcg agggaggctt ccatgacgcg gggcgagagc aggtgcacat
    19741 gggtgtcgat cgccccggcg gtcgcgatca gcccctcccc cgacacgatc gtggtgccgg
    19801 tgccgaccac cacgtcgacc ccgtcgagcg tgtccgggtt ccccgcgcgc cccacggcgt
    19861 ggatgcggcc ttcccggaca ccgatcgaga ccttccggat gccgagcacc gcgtcgatca
    19921 cgagcacgtt gctgatcacc aggtcgcagg tgtcgcgcac ggcggcggcc cgcaggtgca
    19981 gcccgtcccg cgcggtcttc ccgaacccgg ccaggaactc gtcgccgggc cgctgcgcgt
    20041 cggccccgac ccgcaccgtc agccccgtgt caccgagccg caccctgtcc ccggcgcggg
    20101 ggccgtggac ggcggcgtag gcgtacggat cggaggccgt ggccgcctcg tcgggcgcgg
    20161 tacggcggcc gtgcggggta cgggccaggt gcgggaaggc gcgggggcgc ggggtcagct
    20221 cctcaggcag ggcccggccg gcggggtcgc tcatacgtcg gtctccgggg tgggggcgcc
    20281 cggcggggcg ggggtggtgc cgggcggggc gggctccgtc ccgggtgctt cggcgccgag
    20341 gtagccgcag gcggcggcgc ggcgcagggc ctcggcgcgg gcgccggggg cgtccagcgg
    20401 gccgtcgacc agcccggcga aacccgtcac gacgcgcgcc ccgccgatcg gcagcagccc
    20461 cgcctcgcgg gtctcgcccg ggccgaagcg gagcgaggag ccggccggga cggcgaggcg
    20521 catgccgtag gcggcggccc ggtcgaagcg caggcgcggg ttggcctcga agaagtggaa
    20581 gtgcgaggtg acgctgaccg ggaccgtggc ggtgttggtg accgccacgg tcagcacggg
    20641 gctcggctcg gcgtggggcg ggcccgggag cagggcgccg ggcgcctggt cgccggtgtg
    20701 gccgccgccg atggggtcgg ccagcacggc gagccgggac ccgtcctcga aaaccgcctc
    20761 gacctggatc tcggtcagca cgtcggcgac gcccggcagc acgtcgtccg gcccgagcac
    20821 ggcccgcccc gccgccaccg cctccgccag ccgcgccccg tcccgcgccg cctcgcagac
    20881 cgtgtccgag atgagcgcgg tcgcctccgg gacgttcagc cgcagcccgc gcgcctgccg
    20941 ggcccgggcg agctgggcgg cgttgaagat caggaggcgg tcgcgttcgg tgggggtcag
    21001 gcgcatgggg gtcctggagg gagggggtgg gcggcgggcg cggggcgatg gagcgtcacc
    21061 ctatctaaag ggtttaggtt ttccaatgga cggcgcacgg cggggcgggc ggcacttgag
    21121 ccggggcggc tgcccggagc ccgcagacgg cccgggtaag gggcggcccc gccccgtcac
    21181 cccgtacctg cggcgccacc tctgaggccg gacggcgcgc gccccctacc ccgtgaagcc
    21241 gcaggtcgcg cgccccgtgg ccgccccgta cgccgctcgc cccgtcgcgg cgcgcgtaag
    21301 cccgacgccg cgacggcacc ccttaccccc ggagaccggg acccgggcgc cgcccccgga
    21361 ccgaaacggc ccgccgcccc cgcatccgct gcggggacga cgggccgtcc cgcccgtccg
    21421 gtcagaccgg tcggaccggt gccaggcgct cccgcgcccc ggccccggcc ctggcctcgg
    21481 cccccgagat tcagcccagc gggtgcatcc acccgtgacg gtcctccgtg cgtcccgtct
    21541 ggagggcgag gagggcctcg cggaggcgga gggtagcctc gccgggttcg ccggtgccct
    21601 gggtccactc gtcggtggcg gtcttgaccc ggccgacggg ggtgatgacg gcggccgttc
    21661 cgcaggcgaa gacctcggtc agggcgccgc tgcggctgtc ctcgcgccac tggtcgatgg
    21721 agacgcggcc ctcctcggcc cggtagccga ggtcggcggc gagggagagg agggtgtcgc
    21781 gggtgatccc ggcaaggagg gagccggtga gggtgggggt gacgaggcgg tcgccgtaga
    21841 cgaagcagag gttcatgccg cccagttcct cgacccactt gtgctcgacc gcgtcgaggt
    21901 aggcgacctg gtcgcagccc tcggcggcgg cctcggcctg ggcgaggagg gaggcggcgt
    21961 agttgccgcc ggtcttggcg tcgccgacgc cgccggggac ggcacggacg cggttctcgg
    22021 agagccagat cgagacgggc ttgacgccgc cggggaagta cgcgccggcc ggggaggcga
    22081 tgaccacgaa gaggtactcg ttggccggct tgacgccgag cccgacctcc gtggcgatca
    22141 tgaagggccg caggtagagg gattcctcgc cgccgtgcgg cgggacccac gccttgtcct
    22201 gggccaccag caggtcgcag gcctcgatga aggtctccac gggcagctcg ggcatggcga
    22261 ggcggcgcgc ggaggcctgg aagcgg
//
