LOCUS       NZ_VOGX01000018        50214 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77 scaffold11_cov50_1_2691061,
            whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000018
VERSION     NZ_VOGX01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   3  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
REFERENCE   4  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1381827
            Orig. end                         :: >1432041
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000018.1.
            Bacteria and source DNA available from MEB Lab.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>50214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="7"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..>50214
                     /SMILES="NC(Cc1ccccc1)C(=O)NC([*])C(=O)NC(C(C)C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>50214
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:>30214](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>30214
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            893..1687
                     /gene="urtD"
                     /locus_tag="FRZ02_RS08355"
                     /old_locus_tag="FRZ02_08355"
     CDS             893..1687
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0033221 - ATPase-coupled urea
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_process="GO:0015840 - urea transport [Evidence IEA]"
                     /codon_start=1
                     /gene="urtD"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469882.1"
                     /locus_tag="FRZ02_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08355"
                     /product="urea ABC transporter ATP-binding protein UrtD"
                     /protein_id="WP_008407438.1"
                     /transl_table=11
                     /translation="MSGTGTESRGGLEISALRVEFDGFTAVDGVDLSVAPGDLRFLIGP
                     NGAGKTTLVDAVTGLARATGSVRFEGAELLGRPVHRIARAGVGRTFQTATVFENLTVLQ
                     NLDIAAGAGRSAATLLRRRKGVPEAVAEALETIGLTALRERPAGVLAHGQKQWLEIGML
                     LVQNVRLLLLDEPVAGMSHEERDATGALLHRIAGERTVVVIEHDMDFLRSYARTVSVLH
                     AGRVLSEGTVDEVRADPAVQEVYLGTAEDAAAVAGAEAVTGA"
     gene            1684..2382
                     /locus_tag="FRZ02_RS08360"
                     /old_locus_tag="FRZ02_08360"
     CDS             1684..2382
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951377.1"
                     /locus_tag="FRZ02_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08360"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_003951377.1"
                     /transl_table=11
                     /translation="MTLLEIDTVHAGYARSTVLHGVSLTVPRDGVAAVLGHNGAGKSTL
                     LRAAAGLLIPSRGAVRLDGEDVTRLRPHQRVARGLAYVPQGQQCFPQLTAAENLRLVAD
                     GRPDGRAATDEALDLFPALRTLGHRPAGLLSGGQRQQLALARALVTRPRLLLLDEPTEG
                     IQPSVVAEIEAAVLALTRRGGLSVLLVEQHVGFALRAAAHYHVLTAGRVTSSGTGGAGA
                     EEVVRGVLRV"
     gene            2713..3474
                     /locus_tag="FRZ02_RS08365"
                     /old_locus_tag="FRZ02_08365"
     CDS             2713..3474
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059206.1"
                     /locus_tag="FRZ02_RS08365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08365"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_003951376.1"
                     /transl_table=11
                     /translation="MGTEERRRGILHTARRDGSVEVNALAALFRVAKETIRRDLHVLEE
                     HGLVRRTHGGAYPVESAGFETTLAVRTTRNVPQKSRIAAAAADLLGDAETVFVDEGFTP
                     QLVAEALPKDRELTVVTASLAVATALAGAEKTAVLLLGGRVRGATLATVGHWAGRMLGD
                     FVVDLAFIGANGISRSYGLTTPDPTVAEVKAQAVRCSRRRVFVGLHTKFGAVSFCRFAE
                     VADFEAIVTDTGLTSAEAQRYSLLGPQVIRV"
     gene            3596..4963
                     /locus_tag="FRZ02_RS08370"
                     /old_locus_tag="FRZ02_08370"
     CDS             3596..4963
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951375.1"
                     /locus_tag="FRZ02_RS08370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08370"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_003951375.1"
                     /transl_table=11
                     /translation="MAPPRPRHGPRRRLLRTGAAAAALALLSGCAGAGGTSFGGGDALN
                     VLMVNNPQMVELQKLTAKHFTKETGIKVHFTVLPENDVRDKVSQDFSNQAGQYDIATIS
                     NFELPFFAKNGWLHELDGYVAKDPGFDQDDILAPLRESLTAEDGKLYAQPFYGESSFLM
                     YRKDIFEEEGLTMPEQPTWKEVAELAKQTDGSRPGMKGICLRGLPGWGEVIAPLTTVVN
                     TMGGTWFTEDWKPQLTSPEFKKATKFYVDLVRSHGERGAPQSGYAECLNNMTQGKSAMW
                     YDATAGAGSLEASGSPVKGKIGYVPAPVEQTKSSGWLYTWAWGLQKASIKSDDAWKFIS
                     WASSKEYEELVGATSGWSNVPAGKRASTYANPEYRAEAGAFADVTEKAISSADPKNPGT
                     QPRPTAGIQFVGVPEFTDLGTRVAQEISAAIAGRQSVDAALATSQKLAEKVAEEYR"
     gene            4960..5928
                     /locus_tag="FRZ02_RS08375"
                     /old_locus_tag="FRZ02_08375"
     CDS             4960..5928
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469884.1"
                     /locus_tag="FRZ02_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08375"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_015506962.1"
                     /transl_table=11
                     /translation="MTTSTAPAKAPRPPAPVPPAATRGSKAKAWATRAPLLPALVFLVV
                     VTQLPFVATLVLSLFDWNSLSPEKRHFTGLSNYASVFTDAALRDAVITTVILTASVVLV
                     SVALGLGFALLLNRRFFGRGMVRTLLITPFLLVPVSAALLWKHALYNPEYGLFNGALNW
                     FGSLFGIEEVVQPDWMSSMPLAAVVAALVWQWTPFMMLILLAGLQSRPDDMMEAARIDG
                     AGRWQMFAFMTLPHLRRYLELGILLGSVYIVQNFDAVFTLTSGGLGTANLPYTVYETFY
                     RAHEYGLASAVGVVAVIGTVLIATVALRVVSSLFREEASRA"
     gene            5925..6791
                     /locus_tag="FRZ02_RS08380"
                     /old_locus_tag="FRZ02_08380"
     CDS             5925..6791
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951373.1"
                     /locus_tag="FRZ02_RS08380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08380"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_003951373.1"
                     /transl_table=11
                     /translation="MSASTTTPATAPATRPRRRVTGVAVTAWVLGLVFCFPALWMVLTS
                     FHAESDAATNPPSFAASLTLDGYRTFFGGGGGPTPWPPLVNSLTASFFSTVLVLLLALP
                     AAYALSIRRVRKWTDVLFFFLSTKMLPVVAGLLPIYLFARNTGLLDNIWLLVLLYTSMN
                     LPIAVWMMQSFLSDVPVSIIEAAQVDGARLPTVLSRVVAPVAAPGIAATALICFIFSWN
                     ELLFARVLTGVVASTAPVHLTTFVTSQGLFLAQLCAASVVVSLPVLAAGYAAQDKLVQG
                     LSLGAVK"
     gene            6788..7783
                     /locus_tag="FRZ02_RS08385"
                     /old_locus_tag="FRZ02_08385"
     CDS             6788..7783
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951372.1"
                     /locus_tag="FRZ02_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08385"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_003951372.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-34, bitscore: 115.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-14, bitscore:
                     50.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAIVEAVGKVSLTTVPDPEPGPRDVVVKVASCGLCGTDLHILQ
                     GEFAPTLPIVPGHEFAGEIVALGSRVTELAVGDKVAVDPSLHCHECRYCRTGRGNLCDN
                     WAAIGVTTAGGAAEYAVAPVANCVRLPEHVDVRDAALIEPLSCAVRGYDVLRGNLGSEV
                     LIYGSGTMGLMMLELAKRTGAARVDVLDVNPDRLATAGLLGCSATAARAEELDRPAGWD
                     IVIDATGNAQAIQDGLGRVAKGGTFLQFGVSDYATTAVIEPYRIYNQEITITGSMAVLH
                     SYERAAALFASGVLDPSVFISDRLPLEQYPEAIDRFRAGEGRKIVVEPWS"
     misc_feature    7880..7897
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            8026..9195
                     /locus_tag="FRZ02_RS08390"
                     /old_locus_tag="FRZ02_08390"
     CDS             8026..9195
                     /GO_function="GO:0016758 - hexosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641595.1"
                     /locus_tag="FRZ02_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08390"
                     /product="glycosyltransferase 87 family protein"
                     /protein_id="WP_146580580.1"
                     /transl_table=11
                     /translation="MAAVWAAAFPMVSSLGPHRVWGASACVGYLCAAVAVLSRRSLGRA
                     VSVWIAGIGAVLVPLVVLVLTGGAQSEVGVVERAGLLTVRQGTPYLADPQAVVEVTPYL
                     PGMALFGLPGAVVADGWEPLRYLGDARLWCAAAFLGCLWAAGRVLGGRGTGQLVGAALI
                     ASPVVALPLAVSGVDLPLTGLLCLALALAARHRPVAAGLALALACSLKWTAWPALAVVA
                     ALLAHRAGLGAALRGTGVAVAGTVLAVLPSALLAPGPLVEQVFAFPTGRGEWETPAASP
                     LPGRLLADLGPFGWYAAMTLLAAGGVAVAVSLWVRPPAGLVPAADRLAVGLCTAFLLAP
                     AGRFGYLALPVLLSVWARLAEAPSRVAPARSRVVAAGSAARPVLVGGDR"
     gene            9192..9923
                     /locus_tag="FRZ02_RS08395"
                     /old_locus_tag="FRZ02_08395"
     CDS             9192..9923
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951370.1"
                     /locus_tag="FRZ02_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08395"
                     /product="FkbM family methyltransferase"
                     /protein_id="WP_129844806.1"
                     /transl_table=11
                     /translation="MSARRTAAVAASLGWGARRLPFVEDEVEGLGAWVRPGAACLDIGA
                     EYGLYTWMLSALAGPTGQVHSVEPLPGPSGWLRTTARLLGARNVTVHRTAIGDRTGHGT
                     LSLPVRRGLPVHGRAYLVEGSRGPGPNAEFHRARSVRTPVRTLDQLVRDIGLEKLSFVK
                     ADVEGAELAVLRGGSATLRRHRPTLLLEIERRHLTKYGGDPAEVLSHLGSYGYRAHRRQ
                     HGRWVPAPWITEDCRNYLFTA"
     gene            9969..11123
                     /locus_tag="FRZ02_RS08400"
                     /old_locus_tag="FRZ02_08400"
     CDS             9969..11123
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407451.1"
                     /locus_tag="FRZ02_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08400"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_010641599.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.7e-36,
                     bitscore: 122.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTLIVTNDFPPRQGGIETFVHAMATRVPGNDVVVYTSSEPGAA
                     AYDATLPFPVIRDPSRMLLPTPRVTRQALRIAREHGCDRAWFGAAAPLAAMAPALRRGG
                     LRRLVATTHGHEIWWARTPGARQVMRRIGENVDVVTYLGEYTRRRIAPALGPRARLARL
                     VPGVDAAEFRPAPGQGRQVREHHGLVGRKVVLCVSRLVTRKGQDTLIRALPRIRHTVPD
                     AALLIVGQGPDQERLRKLADRYGDGHVVFAGGLDHASTTAYYAAADAFAMPCRTRKAGL
                     EAEGLGIVFLEAAASGLPVVVGDSGGAPDTVLDGETGTVVDGSDPVAVADAVTGVLVDP
                     VRAATMGQAGRNWVEDHWSWDRSADRLNQLLTPGTERLPSRASE"
     gene            complement(11186..11851)
                     /locus_tag="FRZ02_RS08405"
                     /old_locus_tag="FRZ02_08405"
     CDS             complement(11186..11851)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407453.1"
                     /locus_tag="FRZ02_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08405"
                     /product="response regulator transcription factor"
                     /protein_id="WP_008407453.1"
                     /transl_table=11
                     /translation="MLRVVLAEDAVLLRAGLVELLSRVGHEVTAAVGDAEELARAVAAD
                     RPDVVITDVRMPPGFRDEGLRAALELRRADPSLPVLVLSQYVATAYATQLLSGSPAAGG
                     LGYLLKDRVGEVTDFLDALDRVASGQTVIDPEVVRVLLQQGTADKPLQRLTPREREVLA
                     VMAEGLNNQAIAQRLTITEASVVKHASSIFMKLELDPAEGNRRVLAVLAHLRRQDPAA"
     gene            complement(11839..13116)
                     /locus_tag="FRZ02_RS08410"
                     /old_locus_tag="FRZ02_08410"
     CDS             complement(11839..13116)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407455.1"
                     /locus_tag="FRZ02_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08410"
                     /product="sensor domain-containing protein"
                     /protein_id="WP_127453801.1"
                     /transl_table=11
                     /translation="MTVAVWEAMRRRPVRFLFGAWPLRSWAFLLSGLVVGPVVLFVCAA
                     LLLVGVGLSVVGVGLLVLLTLAVVGIPVAALERRRLRLVEPEPLLDPHGSLPGTSALPW
                     LRTRLRERATWRELAYTVLLGVVFTATGIGFAALLGLSLILTATPVIVWAIAPDTVMLV
                     PGQPLSDPVAALPGSAAGLVGLVVSAYAGGLLAGVQVRTAQFLLAARDEDFSSRVIELT
                     RSRARLVDAFEAERRRIERDLHDGAQQQLVALTMTLGLAELELRGQDSGAAPLVSRARD
                     EARQALDQLRSLVRGIHPQVLTDHGLPAAVAELALRNPVPVIVDLDLPHRLPSAVETTA
                     YFTVTEALTNASKHSGADQVSVVGRLRDDTLVLLVTDDGHGGADPEAGAGLQGLADRVA
                     ILKGRLIVTSPVGGPTQLRVEVPCSV"
     gene            13266..14012
                     /locus_tag="FRZ02_RS08415"
                     /old_locus_tag="FRZ02_08415"
     CDS             13266..14012
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951366.1"
                     /locus_tag="FRZ02_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08415"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003951366.1"
                     /transl_table=11
                     /translation="MPLLTDIQLPAVQLAAVSKSYPSSAGPVPVLREVSLGFPQRALTA
                     VMGPSGSGKTTLLNCAAGLDKPDTGKVLLGETDLAACGERELTVVRRSRIGFVFQQFNL
                     LPMLTVYENVALPLRLQRGRVRRERVMEALRQVGLEDKAGRRPAQLSGGQQQRVAIART
                     LVAEPEIVFADEPTGSLDRKSGRQIMELLRDTVDRAGRTVAMVTHDPAAAACADRVVFL
                     SDGQVVGRLDHPTAEAVARQLSLWER"
     gene            14012..16006
                     /locus_tag="FRZ02_RS08420"
                     /old_locus_tag="FRZ02_08420"
     CDS             14012..16006
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010641604.1"
                     /locus_tag="FRZ02_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08420"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_146580582.1"
                     /transl_table=11
                     /translation="MWRISVQSVRHYWALFAGTFVALALGVALIGVSASALAATWAVDA
                     TPDGSAPSVTLKDGTGAARTLSSGDLDMGGVQSVLAMAGVVSAFVTVFVIAGTCAFGIA
                     LRRRDMGLLRLVGAGGGQVRRMVLGESLAVAVPAAVAGCAVAAVAAPLAVEALNGTGLS
                     PVDLRPGPLLWPLVFAAGSGLVIAVLGMLAASKRAARVRPTEALREADLDSRTMTAGRA
                     VTGVLALLGGAVMVALAPGSGTEAATPLALFGTMALAVAATLLGPLYLPPLLRVMALPL
                     RWADPVAGRLAAESVRTSRRRTASLVGPVLAILAIVGVFTTVLSTTGAATSADDRARTT
                     AQLVVEPAGDGGSLDQEAVDRLREDPRVAAVSAPAPLEIAVAGPHSAWKEQAALADPVA
                     LSRTHRITVVDGSLKPLEPGTVAISREFAEWYGHRAGSTVTYGLFGGEPVRAKVAAVLD
                     GGSAVPSVVLPPDTRGATPAPAPERAAVLLDERGAASAGAAAAQLTERLGADRVRVLPT
                     ETWFGRSATDQDRLNNLVLAVLTVPASLYALIAVASTLVMSYSRRGREITGMRMIGVSA
                     GQVRRMALWETLATTTLGTLIAAAVVAWGVRAYQGSLSVFGGGAPLSVPWGMLGTLVAA
                     CVLVGVVVSLAATGRLLRRVSTASTATRQ"
     gene            16291..16962
                     /locus_tag="FRZ02_RS08425"
                     /old_locus_tag="FRZ02_08425"
     CDS             16291..16962
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951364.1"
                     /locus_tag="FRZ02_RS08425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08425"
                     /product="response regulator transcription factor"
                     /protein_id="WP_003951364.1"
                     /transl_table=11
                     /translation="MRVAIAEDSALLRAGMARLLADEGIDVIASLGDTTEIVEVVRKCR
                     PHVVIMDVRMPPTHTDEGIRAAVEIQRMDTGTAVLLLSQYVEPTYAEELVREAPAGTGY
                     LLKQRVGDFAEFLSALHRVRQGETVLDSDIFKQFVGSPREKHATELLTPRERQVLELMA
                     TGLTNSGIVNRLGISERAVEKHVTSILGKLRIANSGENHRRVLAVLNYLRGIERLHDRS
                     E"
     gene            16981..18354
                     /locus_tag="FRZ02_RS08430"
                     /old_locus_tag="FRZ02_08430"
     CDS             16981..18354
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506965.1"
                     /locus_tag="FRZ02_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08430"
                     /product="sensor histidine kinase"
                     /protein_id="WP_146580584.1"
                     /transl_table=11
                     /translation="MKFSTSYRVAAGLIYLSIGSLVGLLLAPLLLLSLVLRLASWLPLV
                     AVPKAVLLCVRAGSAVGRWRAGGRAPGPPGRDSPMREVLRQLPARMAVLHEGLSFSLPL
                     LRAVADLERLLAHSVVGDNGQPDPLRPTAKTEPEERPRAGWDDIRYVGLLLLGTVWLLP
                     LAALAVPVVVFVVTLPLGPPEQLAFGPGNTLTVSGPVTRVTVALAAAALFTVLMGLLLW
                     MGRLRARMVRSILSRIDEAEAHRREEAAERRRIAALRVNDADYRRLERDLHDGAQARLA
                     VILMHLSLAKHRHGEDAGHLRYVIEETHTEIGKALDDIRDLVRGVQPPILSDRGLEAAV
                     TALTERFHVPVEVDSGLGRRPDVRVEATAYYIVAECLANTVKHARATRIRVTLEEHENH
                     LAVSVTDNGTGGASLSGGTGLRGLDDRAAALNGRLDVSSPPGGPTTVTATLPWSLHPL"
     gene            18486..19826
                     /locus_tag="FRZ02_RS08435"
                     /old_locus_tag="FRZ02_08435"
     CDS             18486..19826
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506966.1"
                     /locus_tag="FRZ02_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08435"
                     /product="serine hydrolase"
                     /protein_id="WP_146580586.1"
                     /transl_table=11
                     /translation="MEADLAEDLLRTLTRAHAIPGAQLTVLRAGRSLSLATGVRRTGVA
                     DPVTTETAFALGSVTKAFTATLVGQLVADGELEWDDPVADYVAEFDNAVDEAFSEITLR
                     HLLSHTGGLVADHETDDVAETSLARYTASVSAATRTLHRPGSCFSYANSGYNILGRTVE
                     AVTDMKWQAALANLVLRPLGIDPVFVHDAPGGQRALAQCHTVRPGENRSATPVGLFLPP
                     SWAPAGGLAGSADDLAALATLLLGTHPDAAELLPEEQRTEMCARTPEADAFGMADAWGL
                     GLAHHVSPDGVWLGHDGTVDGGTAHLRFRPADGTVVALTTNATTGTAMWAELVDALRER
                     GVPVGDHRPLAATTPPLSAGPGRLDGDYRNGDTVFRVRTAESGVPVLTDATGLVADLTV
                     HEDLTFTARRTDTDVAPYTGRFVTDRASGEIHLMQLGGRAARRTAAP"
     gene            20001..>30214
                     /locus_tag="FRZ02_RS08440"
                     /old_locus_tag="FRZ02_08440"
     CDS             20001..>30214
                     /NRPS_PKS="Domain: AMP-binding (258-650). E-value:
                     5.9e-105. Score: 343.1. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (755-822). E-value: 2.1e-26. Score:
                     83.9. Matches aSDomain: nrpspksdomains_FRZ02_RS08440_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (839-1140). E-value:
                     6.9e-105. Score: 342.2. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1304-1692). E-value:
                     3.7e-110. Score: 360.2. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (1800-1866). E-value: 1.9e-24.
                     Score: 77.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_PCP.2"
                     /NRPS_PKS="Domain: Epimerization (1880-2186). E-value:
                     7.9e-131. Score: 429.2. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (2196-2353). E-value: 6.6e-42.
                     Score: 134.9. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (2360-2660). E-value:
                     4.8e-101. Score: 329.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (2821-3219). E-value:
                     1.7e-106. Score: 348.2. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_AMP-binding.3"
                     /NRPS_PKS="Domain: PCP (3331-3398). E-value: 2.4e-24.
                     Score: 77.3. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08440_PCP.3"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951361.1"
                     /locus_tag="FRZ02_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08440"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_146581339.1"
                     /sec_met_domain="Condensation (E-value: 1.6e-71, bitscore:
                     237.9, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-119, bitscore:
                     395.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.1e-14, bitscore:
                     50.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRADAPVNRTVPAQTDFWRARLDGVPPLDLPTDRPRPVIRSSGT
                     ATHERELPAPAAAALAELGRSHSTAPTAVLAAAVTALLARYSGQEDVALGTVSPRSGHT
                     VVVRTAVEPAAPFAALLDDTGRALDEALAHDGVPFADLVEALAPEPDTSVTPYVQAMVA
                     VLDELGPAQRDFDPLDLSVEIAGTRLRVRHSTALFEEATATRLAGHLTVLLAGAAADPA
                     TPLSALPLITDDEFTEVVHVWNDTAREVPAGTFPELFAARVAERPEATAVIDESGPVSY
                     RELDERANRIAHHLLELGAGSDQLIGLCVERGAAMAAGLLGIMKAGAAYLPLDPAYPAD
                     RLAYMLQDSGVRVVVTQRELRDRLPGTDATLVDLAADRAALDARPATAPETTPVAEDLA
                     YAIYTSGSTGRPKGVLVSHAGIGNLAAVQAEAFGVTGDSRVLQFASASFDAAFWEMCMG
                     LLTGAALVMGAKETLAPGEPLAAYAAEHGVTHATLTPATVAVLPEGRGLPEGATLVVAG
                     EASTADLVARWSGGRRMINAYGPTETTVCATMSRPLSGAVVPPIGTPIANFRAYVLDDA
                     LRPVPAGVRGELYLAGPGLARGYQGRPGLTAERFVANPYGAPGERMYRSGDVARWSAGG
                     DLEYLGRADDQVKVRGFRIELGEIESALALHPGVAQAVVVTRNTNLIAYVAAAGKQRPT
                     SDALRAFLAEGLPDHMVPATVVVLDALPLTPNDKVDRKALPDPATVRESEAATEDAPRT
                     AVEETLAAIWTDVLGVPRIGVHDDFFALGGNSILSVRAVSRMRAALGVALPPRVLFDTP
                     TIALLAASVAPEDSGEDSAIPLVPRDGALPMSYGQQRQWFLHDFDPTGAEYHTATGLRL
                     TGRLDTEALRGAVQDLTARHESLRTTFGVVAGRGVQVVHPQLAPEWRTEDVSAVDGSLR
                     EDRLRELVRAQTARPYDLTAGPLVRVLLVRLADDEHICVLGMHHIVTDGWSTGIVLREL
                     GEFYAARTEDRAPELREAAVQYPDFAAWQRGRLESGGLLTRQLEWWRAQLDGITPLELP
                     TDRPRAGVRSTAGATYTFAVPATTASAVKELARREGATLFMALTAAVKAVLARWSGQED
                     IAVGTASSGRNHGDLEELVGYLVNTVVLRSRVDAAMSYGELLAQLKETALEAFAHEDVP
                     FERIVDAVGAARDNSRTPLVQAMVVLQNAPADRARLPGLTVTDHPVHREAAPFDLTVEF
                     FEGEDGLTAQVGYSTALFDEATVARFAGHVTTVLAAAAAEPGRALATLPMLTDAEHHQL
                     VHGWNGATVPPLPGTFPELVAESARRRPDAPAVEDTHTALSYRQLDERANQLAHHLRSL
                     GAGPGTLAGLCLERGVETVVGLLGIMKTGAAYLPLDPGYPADRLAFMLQDSGASLVVTR
                     SELAGRLPDTGAVVVDPAAVAGLRDLPTTAPTPGPRPDDLAYVIYTSGSTGTPKGVLVP
                     HRGIGNLAAAEIERLEVTEESRIVQFASSSFDGAVMEILMALPAGATLVLPPHGPLVGE
                     ALQDFLSARRISHALLAPSAVATLTPDGLEGLRTLVVGGEASTGDLVARWSPGRRMINA
                     YGPTESTVVATMSAPLTGGAVPPIGTPLPNTRVRLLDAALQPVPAGVPGELYIAGPHLA
                     RGYHGRPGLTAERFTADPYGAPGERMYRSGDVARWRADGSLEYLGRADNQVKVRGFRIE
                     LGEIETALGRHPDVRDAVVAVHRDGTGRQRLVGHLVTDRELTTGELRSHLAGSLPDYMV
                     PGLYVRLERLPLTPSGKVDRRALPEPDFRAERGGADHTPPRNRAEEVLAGVWAEVLGIE
                     RVGVHDNFFDLGGDSILSIQVVSRARQAGILLTSRLLFLHQSVAALAEVAGTVEEAATG
                     SGPAEVTGEALLTPVQDWFFAEHTVDPDHYGMSAQVELAPGTDTALLERALAAVAARHD
                     ALRMRYTRQDDGRWVQEYGTAPAQPLAVRDLSGLAAEQREAALHEAASAAQRSLDLAGG
                     GLFKGVFFRLGPSQLPRLFLAVHHLVMDGVSWRIVLEDLATAYAQLAEGRPVDLGARTS
                     SYQQWADRLTGHVRSGAMDHELPYWQAESAHIRPLPRDAGADEAPEANTFGAAATASVR
                     LSRAETRALLQQVPAAYRTRINDVLLTALGRVLRDWAGEPVTVALEGHGREELFDDVDL
                     SRTVGWFTTIHPFRLELPEAPDGPDDWGRSLKAVKERLRAVPGHGIGHGALRHLSEPDT
                     AAHRALAGAPHPEISFNYLGRWDGATGTEGLVRTRLAERLGADQAPAQPRPHLIDVVAA
                     VGDGELRVDWIHAPAVHRTETVQRLADAFLAALRGVVEHCLRPENGGATPSDFPLARLD
                     QAAVDRITGGGRDVEDVHPLTPVQSGMLFHTLSTPRAYTEQMTFELDGVDDPALLATAW
                     QRVADHVGVLRASLEWREVERPLMVVRRQAELPVTHLDWRGLPTAEQEEAVRRLLAEDR
                     GRPVDLTVAPLMRLTLVRLTDTTVRLVCAFHHILLDGWSTFDVLAQTHAAYAELAAGRE
                     HPLPARRPFRAYVDWLERQDLAEAEAYWRETLDGFAAPTPLPALRHTAPGHATGSTARL
                     ARRLDPAASRALFAFARRHRLTVNTVLQGAWTLLLARHAGESDVVFGATVSGRPADLPG
                     ADSMIGMLINTLPVRVRVDESAPAAVWLQALQRAQVEARQYEYVPLPRIQACGAVERGA
                     DLFRTLVVFENYPMDDEAAAAHGLRLRRLAGTEATNYPLNLIAYAGDDLSYTLAYDAAL
                     YDEATAGRLCGRLEALLGSLAAADGGTPVSAVGMLTEAEAEQTVRGWNDTAEELPEASV
                     PELFAARVREHPDAVAVTDAGEELTYRQLDERANRLAHHLVALGAGRGSLVGLCLERGA
                     HAVTALLAVVKAGAAYVPLDPGYPADRLAYMIGDAGVGLLVTEKALRDRLPASGVRALD
                     LDEEAGAIAARPGDAAPVPSPAPDDLAYVMYTSGSTGVPKGVLTPHRAVVRLALASGYT
                     EVRPGDTVAQFASLSFDASTFEVWTALLRGARLAVHPPHVPTTAELGRFLTEAGVTHLW
                     LTAGLFHQVAEDDVTVFAGLRHLLAGGDRLSPEHCARVLDAHPALRLTNGYGPTEATTF
                     TTTHDLRGALGEGSVPLGAPLANTRVYVLDGGLEPVPAGVPGELYIAGAGLARGYHARA
                     GLTAERFTADPFGAPGGRMYRSGDLVAWRPDGTLEFLGRTDGQVKIRGFRVETGEIEAA
                     LVAHPSVGDAAVVPHTDPGSGRTLLVGHLVPAQGAVLPGAAELRARLAASLPEYMLPAA
                     FTALDALPLTANGKVDRRALPDPDGARLATGTAYEAPSSPTETLIAEVWQELLGAERVG
                     LHDNFFELGGDSLLALRTVTQINTVFGTGLTPRTLFDRPTVAEAAAEVEDVILAEL"
     CDS_motif       20388..20489
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0001"
                     /evalue="8.60E-10"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="163"
                     /protein_start="129"
                     /score="30.9"
                     /tool="antismash"
                     /translation="EALAHDGVPFADLVEALAPEPDTSVTPYVQAMVA"
     aSDomain        20775..21950
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_AMP-binding.1"
                     /evalue="5.90E-105"
                     /label="FRZ02_RS08440_AMP-binding.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="650"
                     /protein_start="258"
                     /score="343.1"
                     /specificity="substrate consensus: Phe"
                     /tool="antismash"
                     /translation="FAARVAERPEATAVIDESGPVSYRELDERANRIAHHLLELGAGSD
                     QLIGLCVERGAAMAAGLLGIMKAGAAYLPLDPAYPADRLAYMLQDSGVRVVVTQRELRD
                     RLPGTDATLVDLAADRAALDARPATAPETTPVAEDLAYAIYTSGSTGRPKGVLVSHAGI
                     GNLAAVQAEAFGVTGDSRVLQFASASFDAAFWEMCMGLLTGAALVMGAKETLAPGEPLA
                     AYAAEHGVTHATLTPATVAVLPEGRGLPEGATLVVAGEASTADLVARWSGGRRMINAYG
                     PTETTVCATMSRPLSGAVVPPIGTPIANFRAYVLDDALRPVPAGVRGELYLAGPGLARG
                     YQGRPGLTAERFVANPYGAPGERMYRSGDVARWSAGGDLEYLGRADDQVKVR"
     aSModule        20775..22466
                     /complete
                     /domains="nrpspksdomains_FRZ02_RS08440_AMP-binding.1"
                     /domains="nrpspksdomains_FRZ02_RS08440_PCP.1"
                     /locus_tags="FRZ02_RS08440"
                     /monomer_pairings="Phe -> Phe"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20961..21002
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0002"
                     /evalue="2.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="334"
                     /protein_start="320"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LGIMKAGAAYLPLD"
     CDS_motif       21195..21254
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0003"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="418"
                     /protein_start="398"
                     /score="30.0"
                     /tool="antismash"
                     /translation="AYAIYTSGSTGRPKGVLVSH"
     CDS_motif       21612..21638
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0004"
                     /evalue="2.20E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="546"
                     /protein_start="537"
                     /score="7.8"
                     /tool="antismash"
                     /translation="YGPTETTVC"
     CDS_motif       21741..21830
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0005"
                     /evalue="7.90E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="610"
                     /protein_start="580"
                     /score="46.9"
                     /tool="antismash"
                     /translation="PAGVRGELYLAGPGLARGYQGRPGLTAERF"
     CDS_motif       21915..21980
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0006"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="660"
                     /protein_start="638"
                     /score="39.6"
                     /tool="antismash"
                     /translation="YLGRADDQVKVRGFRIELGEIE"
     CDS_motif       22182..22205
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0007"
                     /evalue="1.90E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="735"
                     /protein_start="727"
                     /score="2.3"
                     /tool="antismash"
                     /translation="KVDRKALP"
     aSDomain        22266..22466
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_PCP.1"
                     /evalue="2.10E-26"
                     /label="FRZ02_RS08440_PCP.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="822"
                     /protein_start="755"
                     /score="83.9"
                     /tool="antismash"
                     /translation="EETLAAIWTDVLGVPRIGVHDDFFALGGNSILSVRAVSRMRAALG
                     VALPPRVLFDTPTIALLAASVA"
     CDS_motif       22329..22358
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0008"
                     /evalue="1.00E-01"
                     /label="PCP_mC"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="786"
                     /protein_start="776"
                     /score="6.5"
                     /tool="antismash"
                     /translation="DFFALGGNSI"
     aSDomain        22518..23420
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="6.90E-105"
                     /label="FRZ02_RS08440_Condensation_LCL.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1140"
                     /protein_start="839"
                     /score="342.2"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIVTDG"
                     /tool="antismash"
                     /translation="ALPMSYGQQRQWFLHDFDPTGAEYHTATGLRLTGRLDTEALRGAV
                     QDLTARHESLRTTFGVVAGRGVQVVHPQLAPEWRTEDVSAVDGSLREDRLRELVRAQTA
                     RPYDLTAGPLVRVLLVRLADDEHICVLGMHHIVTDGWSTGIVLRELGEFYAARTEDRAP
                     ELREAAVQYPDFAAWQRGRLESGGLLTRQLEWWRAQLDGITPLELPTDRPRAGVRSTAG
                     ATYTFAVPATTASAVKELARREGATLFMALTAAVKAVLARWSGQEDIAVGTASSGRNHG
                     DLEELVGYLVNTVVLRSRVD"
     aSModule        22518..27059
                     /complete
                     /domains="nrpspksdomains_FRZ02_RS08440_Condensation_LCL.1"
                     /domains="nrpspksdomains_FRZ02_RS08440_AMP-binding.2"
                     /domains="nrpspksdomains_FRZ02_RS08440_PCP.2"
                     /domains="nrpspksdomains_FRZ02_RS08440_Epimerization.1"
                     /domains="nrpspksdomains_FRZ02_RS08440_TIGR01720.1"
                     /locus_tags="FRZ02_RS08440"
                     /monomer_pairings="X -> D-X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       22587..22694
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0009"
                     /evalue="8.60E-16"
                     /label="C2_LCL_024-062"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="898"
                     /protein_start="862"
                     /score="50.3"
                     /tool="antismash"
                     /translation="YHTATGLRLTGRLDTEALRGAVQDLTARHESLRTTF"
     CDS_motif       22914..22979
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0010"
                     /evalue="4.90E-11"
                     /label="C3_LCL_132-143"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="993"
                     /protein_start="971"
                     /score="35.0"
                     /tool="antismash"
                     /translation="MHHIVTDGWSTGIVLRELGEFY"
     CDS_motif       23028..23066
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0011"
                     /evalue="5.80E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1022"
                     /protein_start="1009"
                     /score="15.7"
                     /tool="antismash"
                     /translation="QYPDFAAWQRGRL"
     CDS_motif       23319..23408
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0012"
                     /evalue="7.20E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1136"
                     /protein_start="1106"
                     /score="37.7"
                     /tool="antismash"
                     /translation="DIAVGTASSGRNHGDLEELVGYLVNTVVLR"
     CDS_motif       23457..23576
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0013"
                     /evalue="9.20E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1192"
                     /protein_start="1152"
                     /score="59.8"
                     /tool="antismash"
                     /translation="KETALEAFAHEDVPFERIVDAVGAARDNSRTPLVQAMVVL"
     aSDomain        23913..25076
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_AMP-binding.2"
                     /evalue="3.70E-110"
                     /label="FRZ02_RS08440_AMP-binding.2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1692"
                     /protein_start="1304"
                     /score="360.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AESARRRPDAPAVEDTHTALSYRQLDERANQLAHHLRSLGAGPGT
                     LAGLCLERGVETVVGLLGIMKTGAAYLPLDPGYPADRLAFMLQDSGASLVVTRSELAGR
                     LPDTGAVVVDPAAVAGLRDLPTTAPTPGPRPDDLAYVIYTSGSTGTPKGVLVPHRGIGN
                     LAAAEIERLEVTEESRIVQFASSSFDGAVMEILMALPAGATLVLPPHGPLVGEALQDFL
                     SARRISHALLAPSAVATLTPDGLEGLRTLVVGGEASTGDLVARWSPGRRMINAYGPTES
                     TVVATMSAPLTGGAVPPIGTPLPNTRVRLLDAALQPVPAGVPGELYIAGPHLARGYHGR
                     PGLTAERFTADPYGAPGERMYRSGDVARWRADGSLEYLGRADNQVKVR"
     CDS_motif       24096..24137
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0014"
                     /evalue="1.40E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1379"
                     /protein_start="1365"
                     /score="15.2"
                     /tool="antismash"
                     /translation="LGIMKTGAAYLPLD"
     CDS_motif       24327..24386
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0015"
                     /evalue="4.60E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1462"
                     /protein_start="1442"
                     /score="31.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVLVPH"
     CDS_motif       24738..24764
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0016"
                     /evalue="1.10E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1588"
                     /protein_start="1579"
                     /score="5.8"
                     /tool="antismash"
                     /translation="YGPTESTVV"
     CDS_motif       24867..24956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0017"
                     /evalue="6.30E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1652"
                     /protein_start="1622"
                     /score="53.6"
                     /tool="antismash"
                     /translation="PAGVPGELYIAGPHLARGYHGRPGLTAERF"
     CDS_motif       25041..25106
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0018"
                     /evalue="3.20E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1702"
                     /protein_start="1680"
                     /score="38.3"
                     /tool="antismash"
                     /translation="YLGRADNQVKVRGFRIELGEIE"
     CDS_motif       25314..25340
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0019"
                     /evalue="2.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1780"
                     /protein_start="1771"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRRALP"
     aSDomain        25401..25598
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_PCP.2"
                     /evalue="1.90E-24"
                     /label="FRZ02_RS08440_PCP.2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1866"
                     /protein_start="1800"
                     /score="77.7"
                     /tool="antismash"
                     /translation="EEVLAGVWAEVLGIERVGVHDNFFDLGGDSILSIQVVSRARQAGI
                     LLTSRLLFLHQSVAALAEVAG"
     CDS_motif       25464..25493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0020"
                     /evalue="2.90E-02"
                     /label="PCP_mC"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1831"
                     /protein_start="1821"
                     /score="8.0"
                     /tool="antismash"
                     /translation="NFFDLGGDSI"
     aSDomain        25641..26558
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_Epimerization.1"
                     /evalue="7.90E-131"
                     /label="FRZ02_RS08440_Epimerization.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2186"
                     /protein_start="1880"
                     /score="429.2"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVMDG"
                     /tool="antismash"
                     /translation="TGEALLTPVQDWFFAEHTVDPDHYGMSAQVELAPGTDTALLERAL
                     AAVAARHDALRMRYTRQDDGRWVQEYGTAPAQPLAVRDLSGLAAEQREAALHEAASAAQ
                     RSLDLAGGGLFKGVFFRLGPSQLPRLFLAVHHLVMDGVSWRIVLEDLATAYAQLAEGRP
                     VDLGARTSSYQQWADRLTGHVRSGAMDHELPYWQAESAHIRPLPRDAGADEAPEANTFG
                     AAATASVRLSRAETRALLQQVPAAYRTRINDVLLTALGRVLRDWAGEPVTVALEGHGRE
                     ELFDDVDLSRTVGWFTTIHPFRLEL"
     CDS_motif       25734..25817
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0021"
                     /evalue="9.40E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="1939"
                     /protein_start="1911"
                     /score="24.5"
                     /tool="antismash"
                     /translation="LAPGTDTALLERALAAVAARHDALRMRY"
     CDS_motif       26028..26093
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0022"
                     /evalue="3.70E-11"
                     /label="NRPS-E2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2031"
                     /protein_start="2009"
                     /score="35.2"
                     /tool="antismash"
                     /translation="LFLAVHHLVMDGVSWRIVLEDL"
     CDS_motif       26502..26552
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0023"
                     /evalue="2.90E-08"
                     /label="NRPS-E5"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2184"
                     /protein_start="2167"
                     /score="25.7"
                     /tool="antismash"
                     /translation="DLSRTVGWFTTIHPFRL"
     aSDomain        26589..27059
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_TIGR01720.1"
                     /evalue="6.60E-42"
                     /label="FRZ02_RS08440_TIGR01720.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2353"
                     /protein_start="2196"
                     /score="134.9"
                     /tool="antismash"
                     /translation="GRSLKAVKERLRAVPGHGIGHGALRHLSEPDTAAHRALAGAPHPE
                     ISFNYLGRWDGATGTEGLVRTRLAERLGADQAPAQPRPHLIDVVAAVGDGELRVDWIHA
                     PAVHRTETVQRLADAFLAALRGVVEHCLRPENGGATPSDFPLARLDQAAVDRI"
     CDS_motif       26607..26669
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0024"
                     /evalue="5.10E-10"
                     /label="NRPS-E6"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2223"
                     /protein_start="2202"
                     /score="31.5"
                     /tool="antismash"
                     /translation="VKERLRAVPGHGIGHGALRHL"
     aSDomain        27081..27980
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="4.80E-101"
                     /label="FRZ02_RS08440_Condensation_DCL.1"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2660"
                     /protein_start="2360"
                     /score="329.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHILLDG"
                     /tool="antismash"
                     /translation="EDVHPLTPVQSGMLFHTLSTPRAYTEQMTFELDGVDDPALLATAW
                     QRVADHVGVLRASLEWREVERPLMVVRRQAELPVTHLDWRGLPTAEQEEAVRRLLAEDR
                     GRPVDLTVAPLMRLTLVRLTDTTVRLVCAFHHILLDGWSTFDVLAQTHAAYAELAAGRE
                     HPLPARRPFRAYVDWLERQDLAEAEAYWRETLDGFAAPTPLPALRHTAPGHATGSTARL
                     ARRLDPAASRALFAFARRHRLTVNTVLQGAWTLLLARHAGESDVVFGATVSGRPADLPG
                     ADSMIGMLINTLPVRVRVD"
     aSModule        27081..30194
                     /complete
                     /domains="nrpspksdomains_FRZ02_RS08440_Condensation_DCL.1"
                     /domains="nrpspksdomains_FRZ02_RS08440_AMP-binding.3"
                     /domains="nrpspksdomains_FRZ02_RS08440_PCP.3"
                     /locus_tags="FRZ02_RS08440"
                     /monomer_pairings="Val -> Val"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       27093..27128
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0025"
                     /evalue="4.10E-03"
                     /label="C1_dual_004-017"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2376"
                     /protein_start="2364"
                     /score="10.3"
                     /tool="antismash"
                     /translation="PLTPVQSGMLFH"
     CDS_motif       27147..27230
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0026"
                     /evalue="3.70E-06"
                     /label="C2_DCL_024-062"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2410"
                     /protein_start="2382"
                     /score="19.2"
                     /tool="antismash"
                     /translation="AYTEQMTFELDGVDDPALLATAWQRVAD"
     CDS_motif       27873..27968
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0027"
                     /evalue="1.40E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2656"
                     /protein_start="2624"
                     /score="62.5"
                     /tool="antismash"
                     /translation="DVVFGATVSGRPADLPGADSMIGMLINTLPVR"
     CDS_motif       28017..28139
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0028"
                     /evalue="1.70E-17"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2713"
                     /protein_start="2672"
                     /score="55.8"
                     /tool="antismash"
                     /translation="QRAQVEARQYEYVPLPRIQACGAVERGADLFRTLVVFENYP"
     aSDomain        28464..29657
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_AMP-binding.3"
                     /evalue="1.70E-106"
                     /label="FRZ02_RS08440_AMP-binding.3"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3219"
                     /protein_start="2821"
                     /score="348.2"
                     /specificity="substrate consensus: Val"
                     /tool="antismash"
                     /translation="FAARVREHPDAVAVTDAGEELTYRQLDERANRLAHHLVALGAGRG
                     SLVGLCLERGAHAVTALLAVVKAGAAYVPLDPGYPADRLAYMIGDAGVGLLVTEKALRD
                     RLPASGVRALDLDEEAGAIAARPGDAAPVPSPAPDDLAYVMYTSGSTGVPKGVLTPHRA
                     VVRLALASGYTEVRPGDTVAQFASLSFDASTFEVWTALLRGARLAVHPPHVPTTAELGR
                     FLTEAGVTHLWLTAGLFHQVAEDDVTVFAGLRHLLAGGDRLSPEHCARVLDAHPALRLT
                     NGYGPTEATTFTTTHDLRGALGEGSVPLGAPLANTRVYVLDGGLEPVPAGVPGELYIAG
                     AGLARGYHARAGLTAERFTADPFGAPGGRMYRSGDLVAWRPDGTLEFLGRTDGQVKIR"
     CDS_motif       28650..28691
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0029"
                     /evalue="3.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2897"
                     /protein_start="2883"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LAVVKAGAAYVPLD"
     CDS_motif       28887..28946
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0030"
                     /evalue="1.30E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="2982"
                     /protein_start="2962"
                     /score="27.0"
                     /tool="antismash"
                     /translation="AYVMYTSGSTGVPKGVLTPH"
     CDS_motif       29313..29336
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0031"
                     /evalue="4.10E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3112"
                     /protein_start="3104"
                     /score="4.2"
                     /tool="antismash"
                     /translation="YGPTEATT"
     CDS_motif       29448..29537
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0032"
                     /evalue="1.30E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3179"
                     /protein_start="3149"
                     /score="49.5"
                     /tool="antismash"
                     /translation="PAGVPGELYIAGAGLARGYHARAGLTAERF"
     CDS_motif       29622..29687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0033"
                     /evalue="1.00E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3229"
                     /protein_start="3207"
                     /score="33.7"
                     /tool="antismash"
                     /translation="FLGRTDGQVKIRGFRVETGEIE"
     CDS_motif       29907..29933
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0034"
                     /evalue="2.30E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3311"
                     /protein_start="3302"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GKVDRRALP"
     aSDomain        29994..30194
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08440_PCP.3"
                     /evalue="2.40E-24"
                     /label="FRZ02_RS08440_PCP.3"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3398"
                     /protein_start="3331"
                     /score="77.3"
                     /tool="antismash"
                     /translation="ETLIAEVWQELLGAERVGLHDNFFELGGDSLLALRTVTQINTVFG
                     TGLTPRTLFDRPTVAEAAAEVE"
     CDS_motif       30057..30086
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08440_0035"
                     /evalue="1.70E-02"
                     /label="PCP_mC"
                     /locus_tag="FRZ02_RS08440"
                     /protein_end="3362"
                     /protein_start="3352"
                     /score="8.7"
                     /tool="antismash"
                     /translation="NFFELGGDSL"
     assembly_gap    30215..30474
                     /estimated_length=260
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            <30475..32061
                     /locus_tag="FRZ02_RS08445"
                     /old_locus_tag="FRZ02_08445"
     CDS             <30475..32061
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (11-79). E-value: 2.8e-24. Score:
                     77.1. Matches aSDomain: nrpspksdomains_FRZ02_RS08445_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (93-389). E-value:
                     1.4e-132. Score: 435.0. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08445_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (396-525). E-value: 3.6e-30.
                     Score: 96.8. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08445_TIGR01720.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506967.1"
                     /locus_tag="FRZ02_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08445"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_261399554.1"
                     /sec_met_domain="PP-binding (E-value: 9.1e-14, bitscore:
                     48.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.6e-53, bitscore:
                     177.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="TTEHTPPRTPTEHLLATTWATVLGTEEIGIHDNFFDLGGDSILSI
                     QVISHARRAGLQLTSKLMFTHQTIAELASVVRHAEPETTGGDVAEAVAGRVELTPVQRW
                     FFDGHTTDPDRYAMSVHVALAPDTDPAVLARALEAIVDHHDALRMRYAPDGEGGWAQEY
                     GERPDGLLTVRDIPADGAEAALHDAADEAQRALDLRGGALVKGVFLRTAGADTPPRLFL
                     AVHHLVMDGVSWRILLEDLATAYAQLAEGRPADLGARTSSYQHWARRLTDHVRSGALDH
                     ETGYWRKASAGAVDLPCDGPASSTYGEVAAESVVLDRETTEALLHRAPAAFRTQINDVL
                     LGALGRVLNTWAGGPVTVALEGHGREELFDDVDLSRTVGWFTTIYPVTLVVPDGPWGTA
                     LKAVRKTLRKVPGRGIGYGALRYLREPDHPDRVALAAAPPPRISFNYLGQWDSADGGRG
                     LVRDRLDALGADQAPGENRPHLIDVVAAVSDGELRIEWMHAPSAHAPSTVRRLADDFAT
                     ALRQIAAAAGN"
     aSDomain        30511..30714
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08445_PCP.1"
                     /evalue="2.80E-24"
                     /label="FRZ02_RS08445_PCP.1"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="79"
                     /protein_start="11"
                     /score="77.1"
                     /tool="antismash"
                     /translation="EHLLATTWATVLGTEEIGIHDNFFDLGGDSILSIQVISHARRAGL
                     QLTSKLMFTHQTIAELASVVRHA"
     aSModule        30511..32052
                     /domains="nrpspksdomains_FRZ02_RS08445_PCP.1"
                     /domains="nrpspksdomains_FRZ02_RS08445_Epimerization.1"
                     /domains="nrpspksdomains_FRZ02_RS08445_TIGR01720.1"
                     /incomplete
                     /locus_tags="FRZ02_RS08445"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       30574..30603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0001"
                     /evalue="3.30E-03"
                     /label="PCP_mC"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="42"
                     /protein_start="32"
                     /score="10.8"
                     /tool="antismash"
                     /translation="NFFDLGGDSI"
     aSDomain        30757..31644
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08445_Epimerization.1"
                     /evalue="1.40E-132"
                     /label="FRZ02_RS08445_Epimerization.1"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="389"
                     /protein_start="93"
                     /score="435.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVMDG"
                     /tool="antismash"
                     /translation="GRVELTPVQRWFFDGHTTDPDRYAMSVHVALAPDTDPAVLARALE
                     AIVDHHDALRMRYAPDGEGGWAQEYGERPDGLLTVRDIPADGAEAALHDAADEAQRALD
                     LRGGALVKGVFLRTAGADTPPRLFLAVHHLVMDGVSWRILLEDLATAYAQLAEGRPADL
                     GARTSSYQHWARRLTDHVRSGALDHETGYWRKASAGAVDLPCDGPASSTYGEVAAESVV
                     LDRETTEALLHRAPAAFRTQINDVLLGALGRVLNTWAGGPVTVALEGHGREELFDDVDL
                     SRTVGWFTTIYPVTL"
     CDS_motif       30769..30798
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0002"
                     /evalue="2.10E-04"
                     /label="NRPS-E1"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="107"
                     /protein_start="97"
                     /score="14.1"
                     /tool="antismash"
                     /translation="LTPVQRWFFD"
     CDS_motif       30823..30930
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0003"
                     /evalue="4.10E-08"
                     /label="C2_LCL_024-062"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="151"
                     /protein_start="115"
                     /score="25.6"
                     /tool="antismash"
                     /translation="YAMSVHVALAPDTDPAVLARALEAIVDHHDALRMRY"
     CDS_motif       31135..31200
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0004"
                     /evalue="1.60E-12"
                     /label="NRPS-E2"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="241"
                     /protein_start="219"
                     /score="39.5"
                     /tool="antismash"
                     /translation="LFLAVHHLVMDGVSWRILLEDL"
     CDS_motif       31594..31644
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0005"
                     /evalue="6.10E-10"
                     /label="NRPS-E5"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="389"
                     /protein_start="372"
                     /score="30.9"
                     /tool="antismash"
                     /translation="DLSRTVGWFTTIYPVTL"
     aSDomain        31666..32052
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08445_TIGR01720.1"
                     /evalue="3.60E-30"
                     /label="FRZ02_RS08445_TIGR01720.1"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="525"
                     /protein_start="396"
                     /score="96.8"
                     /tool="antismash"
                     /translation="GTALKAVRKTLRKVPGRGIGYGALRYLREPDHPDRVALAAAPPPR
                     ISFNYLGQWDSADGGRGLVRDRLDALGADQAPGENRPHLIDVVAAVSDGELRIEWMHAP
                     SAHAPSTVRRLADDFATALRQIAAA"
     CDS_motif       31684..31746
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08445_0006"
                     /evalue="2.70E-09"
                     /label="NRPS-E6"
                     /locus_tag="FRZ02_RS08445"
                     /protein_end="423"
                     /protein_start="402"
                     /score="29.2"
                     /tool="antismash"
                     /translation="VRKTLRKVPGRGIGYGALRYL"
     gene            32101..33066
                     /locus_tag="FRZ02_RS08450"
                     /old_locus_tag="FRZ02_08450"
     CDS             32101..33066
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (95-300). E-value: 6.6e-12. Score:
                     37.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08450_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469385.1"
                     /locus_tag="FRZ02_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08450"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_018469385.1"
                     /sec_met_domain="TauD (E-value: 2.5e-10, bitscore: 37.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDAEKNELARIADEFLAAHPVWAPLEYVDDIRVEAERLPVGVRR
                     FLAGARTAEDAIVVVSNLPVDEDLVPTPSSWQVAEKEGAAVREELVLLLVGSVLGDAFG
                     WNNQQNGRLVHDVCPSKGQENSLTSASSQQQLTLHTEDVFHSCRGDYVALMCLRNPDAV
                     GTTVALVESVEFEEPLREVLHQNRFRFFPDDSHQVVPLHTAEAPSALEERPHEVASVLF
                     GPEDAPYLRIDADFTSPVPGDREAEQVMVQAAELLADAAERVVLAPGEAVFVDNYKVIH
                     GRDTFTPRYDGTDRWLKRTSLVRDIRRTYVRSKSRSRLLG"
     aSDomain        32386..33000
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08450_TauD.1"
                     /evalue="6.60E-12"
                     /label="FRZ02_RS08450_TauD.1"
                     /locus_tag="FRZ02_RS08450"
                     /protein_end="300"
                     /protein_start="95"
                     /score="37.7"
                     /tool="antismash"
                     /translation="GSVLGDAFGWNNQQNGRLVHDVCPSKGQENSLTSASSQQQLTLHT
                     EDVFHSCRGDYVALMCLRNPDAVGTTVALVESVEFEEPLREVLHQNRFRFFPDDSHQVV
                     PLHTAEAPSALEERPHEVASVLFGPEDAPYLRIDADFTSPVPGDREAEQVMVQAAELLA
                     DAAERVVLAPGEAVFVDNYKVIHGRDTFTPRYDGTDRWLKRT"
     gene            33066..34520
                     /locus_tag="FRZ02_RS08455"
                     /old_locus_tag="FRZ02_08455"
     CDS             33066..34520
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506969.1"
                     /locus_tag="FRZ02_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08455"
                     /product="MFS transporter"
                     /protein_id="WP_146580588.1"
                     /transl_table=11
                     /translation="MPGGTAEGSRKGGFTLLWVSSAFAEFAYSTSLIVLPLIVLALTGS
                     PSQAGIIGFVDAAAMLLAGLPAGAVADRFDRRTVMLWCQAALVAVFGSLALLLWADAVS
                     LPALIGLALVNGAATALTMAAGDAMIPSLVAPERLSDAVAMNAARTYAGQLAGTSAGGF
                     LLALKNAFPFVVGCLAHLAGLVLLLFLKRQPSARPDGDRDQTDGRGLLEGVRWIMRHPF
                     LRVGLACATATNFFFGVIYFIVIASAQTSGMNTGLIGLMAGLLGVGGLLGALAAPLLQR
                     LLSGARPVYVVLWAFAVLTVGIAVLPGSWTPGVLLGAVAFAAPTANAFFTTQQLALTPD
                     SHRGRVVSAAAVASGGGGAIAPLASGIVLDLAGRSAGLLGCAAVMAVIALVTTLSPALR
                     DVPDPAAVDPPSDPRPDSQVEPGPVPGRGPGNEPESDAYADSGTETESAPECGARSARE
                     VSPVPGTGRGSEQRQETSPEPAPDKV"
     gene            34583..35761
                     /locus_tag="FRZ02_RS08460"
                     /old_locus_tag="FRZ02_08460"
     CDS             34583..35761
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469387.1"
                     /locus_tag="FRZ02_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08460"
                     /product="cytochrome P450"
                     /protein_id="WP_003951357.1"
                     /sec_met_domain="p450 (E-value: 3.9e-19, bitscore: 65.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIDLANPDLYTTDARFEMWEEYIRSDAKVWSDPGISPSGFWSVF
                     SHRDVSAVLSPKAPFTSEYGMMIGFDAEHADHSGGRMLVVSEGNWHSVLKRLIGPFLSR
                     LRAPELRSVLHEEVREIVERLRSQETTDIALTVGPRLPAAIVCEVIGVPLSEREHLIQL
                     TNHAFGGEESSFDKMTPAEAHTEILFYFHELIERRQKEPGTDLVSALLADGRLSTEDVL
                     INCDNVLIGGNETTRHSITGAFHAFQAFPGALDTLRADPELADRAVEEVVRWTSPAAHV
                     LRVATEDCEIGGQQIREGQAVVAWLAAANRDERLFAHPHRFVVDRAPNRHLGFGTGPHH
                     CLGAALARLELKELLTQLAAEAKAVEPREEVRWMRSNLVQGYSGLEVSMRWR"
     gene            35815..36627
                     /locus_tag="FRZ02_RS08465"
                     /old_locus_tag="FRZ02_08465"
     CDS             35815..36627
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951356.1"
                     /locus_tag="FRZ02_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08465"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_003951356.1"
                     /transl_table=11
                     /translation="MLEICLGVEDLARIRIIGTLGTAFETHLAWGQLGKQQRDALSEWR
                     RTARIRLRRAGATMAKARSASLVETLTSPLPHEGDVFHKMAVEPFWDRIQRLLKAERDS
                     CGREMLAGGVEHVLNNRHSAIRWEAPVLRVANGRPPRRTSLTGQGLTLVPSLFAPHPFL
                     LDDSVGWHGLPILVYNIAPDTEPAAALWQSQEGESALPALLGRTRADVLEALRETRSTG
                     QVADRVHISSPSASKHLTILRRAGFVSTERRQNLAVHSLTPLGEAILG"
     misc_feature    36103..36105
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            36646..37383
                     /locus_tag="FRZ02_RS08470"
                     /old_locus_tag="FRZ02_08470"
     CDS             36646..37383
                     /NRPS_PKS="Domain: Thioesterase (16-234). E-value: 1.2e-47.
                     Score: 155.2. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS08470_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018895941.1"
                     /locus_tag="FRZ02_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08470"
                     /product="thioesterase II family protein"
                     /protein_id="WP_018895941.1"
                     /sec_met_domain="Thioesterase (E-value: 6.9e-46, bitscore:
                     154.3, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.8e-08, bitscore:
                     31.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSALTRYTKPLAPTRRLVCFPHAGGAASFYRDWRRCAPPEVEL
                     IAVQYPGRENRVREPLVATMEELATALAEELLALPPLPTVFFGHSMGAAVAHETLLRVE
                     RSGATHVTRLCVSGRAPRRSPRTSARTDEEVVAAVLALGGTHATVFEDPELRELLLPII
                     ANDYRLIDAYRPVAGTPLLRAAVHALTGADDPQVTPEEAGQWRAVTSGRFALTVLDGDH
                     FYLVPEAERVARAALDPELHVPV"
     aSDomain        36694..37347
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS08470_Thioesterase.1"
                     /evalue="1.20E-47"
                     /label="FRZ02_RS08470_Thioesterase.1"
                     /locus_tag="FRZ02_RS08470"
                     /protein_end="234"
                     /protein_start="16"
                     /score="155.2"
                     /tool="antismash"
                     /translation="RRLVCFPHAGGAASFYRDWRRCAPPEVELIAVQYPGRENRVREPL
                     VATMEELATALAEELLALPPLPTVFFGHSMGAAVAHETLLRVERSGATHVTRLCVSGRA
                     PRRSPRTSARTDEEVVAAVLALGGTHATVFEDPELRELLLPIIANDYRLIDAYRPVAGT
                     PLLRAAVHALTGADDPQVTPEEAGQWRAVTSGRFALTVLDGDHFYLVPEAERVAR"
     CDS_motif       36892..36939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS08470_0001"
                     /evalue="6.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="FRZ02_RS08470"
                     /protein_end="98"
                     /protein_start="82"
                     /score="15.4"
                     /tool="antismash"
                     /translation="PTVFFGHSMGAAVAHE"
     gene            37470..38801
                     /locus_tag="FRZ02_RS08475"
                     /old_locus_tag="FRZ02_08475"
     CDS             37470..38801
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951354.1"
                     /locus_tag="FRZ02_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08475"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_146580590.1"
                     /transl_table=11
                     /translation="MARNRCVLILTLLLCTLGLVAATLPPPEEQARQGAARHAHALRTT
                     DPAGDLADLRPLGRMVGDAKVVGLGEATHSSHEFFTMKHRVLRYLVEEKGFRAFALETA
                     WSTGLRLDAYVRTGDGDPRRIMREEFQDTYAWWNTKEYLALVEWIREWNTDHPKDQVRF
                     LGDDFAYAGPELYDRVLRYAALHQPRLLPRLAELYRGLRPTTSSGTYMKEYLTRPLPER
                     RALATRTTEALALLTRHAPSSGPAAEARAWALQHARAIDQTARGYAFDFDDPEDLRASM
                     GYRDQLMADNVAWWHEQTGDKILLSAHNSHLAYRSADPRYPKMQGAFLRDRLGTAYLSA
                     AMTFGTGSFNATGRDGATTLHTLKAPARNTTEHFLNSVTPTDYYLDLRTAPTPTRTWLS
                     PPRPTRNIGTAYPEPPQKVAPAHSHDVVMHLHRVTGAGLLATPE"
     gene            complement(39290..39481)
                     /locus_tag="FRZ02_RS33345"
     CDS             complement(39290..39481)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRZ02_RS33345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_234373616.1"
                     /transl_table=11
                     /translation="MDERQRKAHSSRRIRVEHGIDHLKNWRSLARHHGRREHKSDTIQA
                     VAGLLSHQQAVTASGTRT"
     gene            complement(39532..40233)
                     /locus_tag="FRZ02_RS08480"
                     /old_locus_tag="FRZ02_08480"
     CDS             complement(39532..40233)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025000.5"
                     /locus_tag="FRZ02_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08480"
                     /product="transposase family protein"
                     /protein_id="WP_234373615.1"
                     /transl_table=11
                     /translation="MIRVVGSRTRAAIIRTQRITGLAPDVIAELVAEIGPLWHERHQAV
                     LTSRPRRGAVGAGAECKLVFVDRLLATLVHLRHATTHDVLACWFGVDRSTITRAIGEVR
                     PLLAERGCTVAPDIRLRTLAEVIDHLGASGQTGIIGGTEVRVRRPAVGRKDREKLIAGK
                     NKQSAVKSPWSSRTPRGGRCSAVRPSLRALRTSRTPGSWAWSSSWPTVRPRRSSPMLAT
                     KAWAPRPEAAW"
     misc_feature    complement(40228..40243)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.57"
                     /tool="antismash"
     misc_feature    40229..40243
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.76"
                     /tool="antismash"
     misc_feature    complement(40235..40249)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            40339..>40620
                     /locus_tag="FRZ02_RS08485"
                     /old_locus_tag="FRZ02_08485"
                     /pseudo=""
     CDS             40339..>40620
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0032196 - transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828364.1"
                     /locus_tag="FRZ02_RS08485"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08485"
                     /product="transposase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MITASEPSWIAPFTGLSPRQFGKLVAVLRREGADAVRKGRPWSLA
                     LEDRSLPVAAYWRTKLTMRQLAPLFGVSKSAADRIIDHLGPMLALQPRK"
     gene            <40611..40973
                     /locus_tag="FRZ02_RS08490"
                     /old_locus_tag="FRZ02_08490"
                     /pseudo=""
     CDS             <40611..40973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407480.1"
                     /locus_tag="FRZ02_RS08490"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08490"
                     /product="tyrosine-type recombinase/integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="APQSSGYVFTRPDGAPIEGSTLTRHFNTLLRRAGLRRIRFHDLRH
                     STTTLLLEQGVELVVIKELLGHAHIGVTATVYAHVRLRLQRDAIDLLGHALRYPAEITD
                     KPDSDDEPPFAGAVVR"
     gene            complement(41126..41383)
                     /locus_tag="FRZ02_RS08495"
                     /old_locus_tag="FRZ02_08495"
     CDS             complement(41126..41383)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033691.1"
                     /locus_tag="FRZ02_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08495"
                     /product="MafI family immunity protein"
                     /protein_id="WP_093853274.1"
                     /transl_table=11
                     /translation="MEAVEYAAKIEELLEESPITAPSVAVDVRDLLVAGEFALAFDTMC
                     SWIYEDELSISEEYYGRLVRLSADLGSRDLIARMRELVTG"
     gene            complement(41394..48347)
                     /locus_tag="FRZ02_RS08500"
                     /old_locus_tag="FRZ02_08500"
     CDS             complement(41394..48347)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008407482.1"
                     /locus_tag="FRZ02_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_08500"
                     /product="polymorphic toxin-type HINT domain-containing
                     protein"
                     /protein_id="WP_146580592.1"
                     /transl_table=11
                     /translation="MHVTSRRGFRRARTRRIALGAALTMVATLLQVSAVAAPAVADNPL
                     PGVPSSERPTEGAPAGKGTPRNKRPSPVPTGKPDAAWPKAGATDVVLASADSAGQPDVQ
                     AKGLPLKLGAAEKKAQTPSTVRARVLDRATTERAGVQGVLLSLENEDDSRTAKGGGVSV
                     SLKYASFAEAYGAGFGSRLTLVTLPECALETDRRSDCGGAVPVDTVNDAEKQTLSAASV
                     PLRAGRTLLAAVADDSGPIGDYKATSLSPASSWSTDLNSGDFNWAYGFEAPAVPGGAAP
                     KVGVSYSSGAIDGRASGTNNQGSWVGDGFDYSPGFIERRYKPCADDGVKNADGNEPGDL
                     CWAYDNAFLSFNGKGGELVPTGQDTWKLQQDDGTLIKRLASTDRGNGDNDGEYWRITDP
                     QGNRYYFGYHRLPGWTDGKDTTGATWTVPVFGNDAGEECHKSTFAASWCQQAWRWNLDY
                     AVDVRGNAIAYYYNQEKNSYGRNLEAKDNTRYVRGGHLDRIEYGLKHDSVYSAKAMAKV
                     DFTSSERCIEKDAGDCADIEKNAFHWYDTPWDMNCPEAKDCDKGRYAPTFWTRKRLTGV
                     TTGVLNTAGSGYDKVDSWKITHRWEKADINYQLVVDSIQRTGHTATTPVTLPKTTLSYT
                     QLANRMDKTGDGYPPFIRARLSTVEDETGGRADVNYSAPVCDSAALPTPQTNTTRCYPQ
                     INEGQGDEKPYTHWFNKYVVDYVTLTDRTGGAPDQVTRYEYLGGGAWHYDDSDGMVEDD
                     IRTWSQWRGYGHVRVLDGGEGGDSAMRSQSDSYFMRGMNGDRKEPSGGTKSVSLPLGEG
                     EGDPITDHESAAGFLYKSAGYSGPGGRVLGKTLERPWYYETAEKKRNWGTIRSHFTGTA
                     SSRTWTSTDDGAGKEWRITSKSTTYDADSGRVLQIDNRGDNATAADNQCTRHEYVPNAE
                     LNILAALYRSETVAVSCDVAPDRAKDVLTDTLTAYDGQAYGAAPAKGNPTAVAALKSHD
                     GTKAIYLENSSTFDAYGRILSTTPLSADVQVTGETAPKRTPRTGATTSTISYTPARGRL
                     SSVTSTTPPAKAGQAATAQKTVTTLDPRRGSPLVVTDPNGRATTREYDALGREAKIWLP
                     DRKTGVTPNYSFDYYIEDGLPTAVRTRSLSNAGGTLDSYELYDGHLRPRQTQTPGVEGG
                     RIITDIFYDERGLASRSFAPYYTESAPSRNLFTPANALSVESQTWHTYDGMGRETEQRH
                     VAGGVDGGKVLALTRTLYGGDRTTVIPPEGASATTALTDAQGRTIELRTHHGRSVADAY
                     DSIRYRYNSGGLLQSATDPMGNTWSYTYDQLGRATQTVDPDAGRTVQQYNDRNQVVTST
                     DARGRTVHHTYDDLGRQTALRDDGPTGTLRAEWEYDTVSSAKGFLASSTRYVDGEAYVS
                     KITKYDALYRPERSAVTIPASEGEALAGTYQAGTAYHPSGLVKSATVSAAGGLPGTTQT
                     YQYDEALRIVGTVAYNGQNTITRSLTGKPLQYTFQKEPGAERTQVTQAFEWGTQRLATS
                     TVARENGIGIDREQTYRYDAIGNILSVTDVSRDGIDTQCYTYDHLRRLTEGWTQGTQEC
                     ADKPTSNVVGGIAPYWDSYTYDKAGNRLTEVRHGHGAAAGDDVTRAYTYPAAGGPQPHT
                     LTEVTQSGPGGTSKAAYAYDASGNTTERMINGDTQKLTWDAEGKLVRVAQPVEGEDDEV
                     TEYLYDADGNRLIARSPTETTLYLGHTDVTVAKGATKAKATRYFELGDGHQLVLDDDRN
                     ATVTIADHQGTGQLAVNIDGKELTQRRTTPFGQPRGTQPESWPGKRAFVGGIDDTATTG
                     LTHLGAREYDRDTGRFISVDPILDLTDTQQIHGYTYANNSPITFSDPSGLRPEGACGGS
                     SSQCNGGTETWNKKGGKWTWNYETVKSDGTRDVAYHTLGGGSTVRAIFPSDQGNKDGSA
                     EAVEILEIRIPSEKELAAMYPYKDGYEGRVEEHILRLCRGGGEGDKAAPFCSVMRETSL
                     FEGGGDWRDLVPFMDVPECVGGSVSACAWLALDATPIGRIKALKGIAKGAKGAKGVDSD
                     VMTILKTCKKCFLAGTQVLMADGTTKAIEEVELGDEVLATDPVTGETVAEEVAATIVTD
                     NDKVFVELTVGTPEGPERLTATHEHPFWSVSAKEWVDAEDLTPGTRLRTDDGRTVAVEK
                     VRRYADEARTYNLTITDLHTYYVLAGQTPVLVHNSNCAGAGRDLIGGQEQFHIIHGDRT
                     GGGHKWPGQPGKTVFPRGWDTDKILDSIADVATSPNSVRTQQTGRAGALYTRNGDPSRW
                     KVEGVVDGVNIRVIYEPATDRIVTGFPYRP"
     misc_feature    49430..49450
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.48"
                     /tool="antismash"
ORIGIN
        1 tcttcggcct cggcggctac gccatggcga tgcacctgaa actggccgac gcgggccccg
       61 gcaacctccc cgacttcatg gtcctctacg gcacgaccga caccctgccc tggtggtggg
      121 tgcccttcgc caacccggtc ttcgccctcg ccgccaccgt gctgctgccg atgggcgtgg
      181 ccacgctgct cggttcgctg atcttccggc gccgggtgcg cggcgcgtac ttcgccctgc
      241 tcagccaggc gctgacggcg gccttcgcga tctggctggt cggccagcag gcgaccaccg
      301 gcggcaccaa cggcctcacc gacatccagg gcttcttcgg ctacgcgctc gacgacccgg
      361 ccaaccagcg gatggtctac ttcgtcatcg ccctggtcct gctcgcgctg atcgccctgg
      421 cccgccagct gatccactcc cggtacggcg aactcctcgt cgccgtccgc gactccgagg
      481 aacgcgtccg cttcctcggc tacgacccgg cccgcgtcaa gctcgtcgtc tacgtggtcg
      541 cggcgggcat ggcgggactg gcgggcgccc tgttcgtccc ggccgtcggc atcatctcgc
      601 cggcgctgat cggcatcgtc ccctcgatcg agctggtgat cggcgcggcc gtcggcggcc
      661 gggccagcct gctcggcgcg gtgctcggcg cgctcgccgt ggcctgggcg aagacggcgc
      721 tctccgcgga gttcccggcc gcctggacct acttccaggg gctgctgttc gtggtggtgg
      781 tcgccttcct gccgggcggc ctcgcctccc tggccaggac cgtacgggca cggctcgccc
      841 ggcgccgtac gggcgcggac gaggacggcg cggagcagaa ggaggcggcg gtatgagcgg
      901 caccggcacg gagtcccggg gcgggctgga gatcagcgcg ctgcgggtgg agttcgacgg
      961 gttcaccgcc gtcgacgggg tggacctgag cgtcgccccg ggcgacctgc gcttcctgat
     1021 cgggccgaac ggggcgggca agaccactct ggtcgacgcg gtcaccgggc tcgcccgggc
     1081 caccggctcg gtccggttcg agggcgccga gctgctcggg cggcccgtcc accggatcgc
     1141 ccgcgcgggc gtcggccgta ccttccagac ggcgacggtc ttcgagaacc tcaccgtcct
     1201 gcagaacctc gacatcgcgg ccggcgccgg acgctccgcc gccaccctgc tgcggcgccg
     1261 caagggcgtc cccgaggcgg tcgccgaggc gctggagacg atcgggctga ccgcgctgcg
     1321 cgagcgtccc gccggggtcc tcgcccacgg gcagaagcag tggctggaga tcggcatgct
     1381 gctggtccag aacgtgcggc tgctgctcct ggacgagccg gtggccggca tgagccacga
     1441 ggagcgggac gccaccggcg ccctgctgca ccggatcgcg ggcgagcgga ccgtggtcgt
     1501 catcgaacac gacatggact tcctgcggtc ctacgcgcgc acggtgagcg tgctgcacgc
     1561 gggccgggtg ctgagcgagg ggacggtgga cgaggtgcgg gccgatccgg cggtgcagga
     1621 ggtgtacctc ggcaccgccg aggacgccgc ggcggtggcc ggggccgagg cggtgaccgg
     1681 cgcatgacgc tcctggagat cgacacggtg cacgccgggt acgcccgctc caccgtcctg
     1741 cacggcgtct ccctgaccgt gccccgcgac ggggtcgcgg ccgtcctcgg ccacaacggc
     1801 gcgggcaaga gcaccctgct gcgcgcggcg gccgggctgc tgatcccctc gcgcggcgcc
     1861 gtccgcctcg acggcgagga cgtcacccgc ctgcgcccgc accagcgggt ggcccgcggc
     1921 ctcgcctacg tcccccaggg ccagcagtgc ttcccccagc tgaccgccgc cgagaacctc
     1981 cgcctggtcg ccgacggccg gccggacggc cgggccgcca ccgacgaggc cctcgacctc
     2041 ttcccggccc tgcgcaccct cggccaccgc cccgcgggcc tcctctccgg cggccagcgc
     2101 cagcaactcg ccctggcccg agccctggtg acccgccccc gcctgctcct cctggacgag
     2161 ccgacggaag gcatccagcc ctcggtggtc gccgagatcg aggcggccgt cctcgccctc
     2221 acccgccgcg gcggcctctc cgtcctcctc gtcgaacaac acgtcggctt cgccctccgc
     2281 gccgccgccc actaccacgt cctgacggcg ggccgggtga cctcgtcggg aacgggcggg
     2341 gcgggggcgg aggaggtggt gcggggggtg ctgcgggtgt agccgggcag ggcaccaccg
     2401 gcacccgggg cgcgtacgga agcggaagga cagccgcggc cgcacgcgcc cgatcggggc
     2461 cccgaaccgg acacgggcat tttccggtcg ccgatctggc ccgaaacggg catcactccg
     2521 tgtcgcgtcg gagcctccgc ctatgctgac cagcacggtc catgccgccc gaacgggcaa
     2581 gaacgggcaa gagcaccccc gcacaggagg tggccgagcc acgggcgctg cttgtacaaa
     2641 cgacacgtga gcccgaacgg accggtccgg gctccgcagt ggaccgcacc gaagcagaac
     2701 cggaagggcg tcgtgggcac cgaggaacgc cgcagaggga ttctccacac cgcccgccgg
     2761 gacggctcgg tggaggtgaa cgcgctcgct gccctgttcc gcgtggccaa ggagaccatc
     2821 cgccgtgatc tgcacgtact ggaggaacac ggtctggtac gccggacgca cggcggggcc
     2881 tatcccgtgg agtcggcggg gttcgagacc acgctggccg tccgcaccac ccgcaacgtg
     2941 ccgcagaagt cgcggatcgc ggcggccgcg gccgacctgc tcggggacgc cgagacggtc
     3001 ttcgtcgacg agggcttcac cccccagctc gtcgccgagg cgctgccgaa ggaccgcgaa
     3061 ctgaccgtcg tcaccgcctc cctggccgtc gccaccgcgc tggccggggc ggagaagacc
     3121 gccgtgctgc tgctcggcgg gcgggtgcgc ggcgccaccc tggccaccgt cgggcactgg
     3181 gccgggcgga tgctcggtga cttcgtggtc gacctggcgt tcatcggcgc caacggcatc
     3241 tcccgctcgt acggcctgac caccccggac ccgacggtcg ccgaggtgaa ggcgcaggcg
     3301 gtgcggtgct cgcggcggcg ggtcttcgtc gggctgcaca ccaagttcgg cgcggtgagc
     3361 ttctgccggt tcgccgaggt cgccgacttc gaggccatcg tcaccgacac cggcctcacc
     3421 tccgccgagg cccagcgtta ctccctcctc ggtccccagg tcatccgcgt ctgaccgacc
     3481 tggccggtcc cacccctgtc cgcacggcac cgccccacgc gcgtgccggg gcgcggtccg
     3541 ccgcgcccgt acaccccctt tcccccatcg agccgcgacc cctcaggagt tccccatggc
     3601 ccctccgcga ccacgccacg gaccgcgccg ccgccttctg cgaaccggag cggcggcggc
     3661 cgcgctggcg ctgctctccg gatgtgccgg ggcgggcggc acctcgttcg gcggcggcga
     3721 cgcgctgaac gtcctgatgg tgaacaaccc gcagatggtc gagttgcaga agctcacggc
     3781 caagcacttc accaaggaga ccggcatcaa ggtgcacttc acggtgctgc cggagaacga
     3841 cgtgcgcgac aaggtcagcc aggacttctc caaccaggcc ggccagtacg acatcgccac
     3901 catcagcaac ttcgagctgc ccttcttcgc gaagaacggc tggctgcacg agctggacgg
     3961 ctacgtcgcc aaggaccccg gcttcgacca ggacgacatc ctcgccccgc tgcgcgagtc
     4021 gctgaccgcc gaggacggca agctctacgc ccagccgttc tacggcgagt cctccttcct
     4081 gatgtaccgc aaggacatct tcgaggagga ggggctgacc atgcccgagc agcccacctg
     4141 gaaggaggtc gccgagctgg cgaagcagac cgacggctcc cgccccggga tgaagggcat
     4201 ctgcctgcgc gggctgcccg gctggggtga ggtcatcgcc ccgctgacca cggtggtcaa
     4261 cacgatgggc ggcacctggt tcaccgagga ctggaagccg cagctgacct caccggagtt
     4321 caagaaggcc accaagttct acgtcgacct ggtccgctcc cacggcgagc gcggcgcccc
     4381 gcagtccggg tacgccgagt gcctgaacaa catgacccag ggcaagtcgg ccatgtggta
     4441 cgacgccacg gccggcgcgg gctccctgga ggcgtccggc tccccggtga agggcaagat
     4501 cgggtacgtc ccggcccccg tcgagcagac caagagctcc ggctggctct acacctgggc
     4561 ctgggggctg cagaaggcgt ccatcaagtc cgacgacgcc tggaagttca tctcctgggc
     4621 ctccagcaag gagtacgagg agctggtcgg cgccaccagc ggctggtcca acgtccccgc
     4681 gggcaagcgc gcctccacct acgccaaccc ggagtaccgc gccgaggccg gggccttcgc
     4741 cgacgtcacc gagaaggcca tctcctcggc cgacccgaag aacccgggca cccagccccg
     4801 cccgaccgcc ggcatccagt tcgtcggcgt accggagttc accgacctgg gcaccagggt
     4861 cgcccaggag atcagcgccg ccatcgcggg ccgccagtcg gtggacgccg cgctcgccac
     4921 ctcccagaag ctggccgaga aggtcgcgga ggagtaccga tgaccacatc caccgccccg
     4981 gcgaaggcac cgaggccgcc cgcgcccgtg ccgcccgccg ccacccgggg cagcaaggcc
     5041 aaggcgtggg cgaccagggc gccgctgctg cccgcgctgg tcttcctcgt cgtcgtcacc
     5101 cagctgccgt tcgtggcgac gctcgtcctc tccctcttcg actggaactc cctcagcccg
     5161 gagaagcgcc acttcaccgg cctgtccaac tacgcctcgg tcttcaccga cgccgccctg
     5221 cgcgacgcgg tgatcaccac ggtgatcctg accgcctcgg tggtcctggt cagcgtggcg
     5281 ctcggcctcg gcttcgccct gctcctcaat cgccgcttct tcggccgcgg catggtccgc
     5341 accctgctca tcacgccgtt cctgctggtc ccggtctcgg ccgcgctgct gtggaagcac
     5401 gcgctgtaca acccggagta cggcctgttc aacggcgcgc tcaactggtt cggctcgctc
     5461 ttcggcatcg aggaggtggt ccagccggac tggatgtcgt cgatgccgct ggccgccgtg
     5521 gtggccgccc tggtgtggca gtggacgccg ttcatgatgc tgatcctgct ggcggggctg
     5581 cagagccgcc ccgacgacat gatggaggcg gcccgcatcg acggcgccgg gcgctggcag
     5641 atgttcgcct tcatgaccct gccccacctg cgccgctacc tcgaactggg catcctgctc
     5701 ggctcggtgt acatcgtgca gaacttcgac gcggtcttca ccctcacctc cggcggcctc
     5761 ggcaccgcca acctccccta caccgtctac gagaccttct accgggccca cgagtacggc
     5821 ctggcctccg ccgtcggcgt cgtcgcggtg atcggcacgg tgctcatcgc caccgtcgcc
     5881 ctgcgggtgg tctcgtccct cttccgcgag gaggcgagcc gcgcatgagc gcctcgacca
     5941 caaccccggc cacagccccg gccacccggc cccgccgccg tgtcaccggc gtcgccgtca
     6001 ccgcctgggt gctcggcctg gtcttctgct tccccgccct gtggatggtg ctgacctcct
     6061 tccacgcgga gtccgacgcg gccaccaacc cgccgtcctt cgccgcctcc ctcaccctgg
     6121 acggctaccg caccttcttc ggcggcggag gcggcccgac cccctggccc ccgctggtca
     6181 actccctgac cgcctccttc ttctccaccg tgctggtcct gctcctcgcc ctcccggcgg
     6241 cgtacgccct ctccatccgg cgcgtgcgca agtggaccga cgtgctcttc ttcttcctct
     6301 ccaccaagat gctgccggtg gtggccgggc tgctgcccat ctacctcttc gcccgcaaca
     6361 ccgggctgct cgacaacatc tggctgctcg tcctcctcta cacctcgatg aacctgccga
     6421 tcgcggtgtg gatgatgcag tccttcctct ccgacgtgcc cgtctcgatc atcgaggcgg
     6481 cccaggtcga cggggcgcgg ctgccgaccg tgctgagccg ggtggtggcg ccggtcgccg
     6541 cgcccgggat cgcggccacc gcgctgatct gcttcatctt cagctggaac gagctgctct
     6601 tcgcccgggt gctgaccggt gtcgtcgcct cgaccgcccc cgtccacctg accaccttcg
     6661 tcaccagcca gggcctcttc ctggcccagc tctgcgccgc ctcggtggtc gtgtccctgc
     6721 cggtgctcgc cgccggctac gccgcccagg acaaactcgt ccagggcctc tccttgggag
     6781 cagtcaaatg aaggcagcca tcgtcgaagc cgtgggcaag gtgtccctca ccaccgtgcc
     6841 cgacccggag ccgggtccgc gcgacgtggt cgtcaaggtc gcctcctgcg ggctgtgcgg
     6901 caccgatctc cacatcctgc agggcgagtt cgccccgacg ctgccgatcg tgccgggcca
     6961 cgagttcgcc ggcgagatcg tcgccctcgg ctcccgtgtc accgaactcg ccgtcggcga
     7021 caaggtcgcc gtcgacccct ccctgcactg ccacgagtgc cgctactgcc gcacgggccg
     7081 cggcaacctg tgtgacaact gggccgccat cggcgtcacc acggccggcg gcgccgccga
     7141 gtacgccgtc gcccccgtcg ccaactgcgt ccgtctcccc gagcacgtcg acgtccgcga
     7201 cgccgccctc atcgagccgc tctcctgcgc ggtgcgcggc tacgacgtgc tccgcggcaa
     7261 cctcggctcc gaggtcctca tctacggctc gggaaccatg ggcctgatga tgctggaact
     7321 ggccaagcgc accggcgccg cccgcgtcga cgtcctcgac gtcaaccccg accgcctggc
     7381 caccgccggc ctcctcggct gctccgccac ggccgcccgc gcggaggaac tcgaccgccc
     7441 cgccggctgg gacatcgtca tcgacgccac cggcaacgcc caggccatcc aggacggcct
     7501 cggccgcgtc gccaagggcg gcaccttcct ccagttcggc gtctccgact acgccaccac
     7561 cgccgtcatc gagccctacc gcatctacaa ccaggaaatc accatcaccg gctccatggc
     7621 cgtcctccac agctacgaac gggccgcggc cctcttcgcc tccggcgtcc tcgacccctc
     7681 ggtcttcatc agcgaccgcc tccccctgga gcagtacccg gaggcgatcg accggttccg
     7741 ggcgggcgag ggcaggaaga tcgtcgtgga gccctggagc tgaggctctg gaactgagga
     7801 cagaacgccc ctccccggcg gctcgaccgg ggaggggcgt tcccgtcgtt cgcccgggcc
     7861 ggcgtccacg gcctgcccgt ctcccatggt ggggaaaacc ccaccacaag gtctcgacct
     7921 ggctgtcatg acctggggcg gggagttggc tgcaatggtc tggtgctgac tcaccgggta
     7981 caacagtctt tggaaagccg gaagttgtgg tgctgcggat ggctcgtggc cgcggtctgg
     8041 gccgccgcgt tccccatggt ctcctcactc gggccgcatc gcgtctgggg cgcgagcgcc
     8101 tgcgtcgggt atctctgcgc ggccgtggcg gtcctctccc ggcgctcgct cggacgggcc
     8161 gtctcggtgt ggatcgccgg gatcggggcc gtcctcgtgc ccctcgtggt gctcgtgctg
     8221 accggcgggg cgcagagcga ggtcggcgtg gtcgagcgcg ccgggctgct gaccgtacgt
     8281 cagggcacgc cgtacctggc cgatccgcag gccgtcgtgg aggtcacccc gtacctgccc
     8341 ggcatggcgc tgttcgggct gccgggggcg gtggtggccg acggctggga accgctgcgg
     8401 tacctcgggg acgcgcggct ctggtgtgcg gcggccttcc tcggctgcct ctgggcggcg
     8461 ggccgcgtcc tcggcggccg gggcaccggg cagctcgtcg gtgccgcgct gatcgcctcg
     8521 ccggtggtgg cgctgccgct cgccgtcagc ggtgtcgacc tcccgctcac cggcctgctc
     8581 tgcctggccc tggcactggc cgcccggcac cgtccggtgg ccgccgggct cgccctggcg
     8641 ctggcctgct ccctgaagtg gacggcgtgg cccgccctcg ccgtcgtcgc ggctctcctc
     8701 gcccatcgcg cggggctcgg tgccgccctg cgcggtacgg gggtcgcggt ggccgggacg
     8761 gtgctggccg tcctcccgag cgccctgctg gcgccgggtc ccctggtcga gcaggtcttc
     8821 gcctttccca ccgggcgggg tgagtgggag accccggcgg ccagtccgct gcccggccgg
     8881 ctcctggccg acctcggccc gttcggctgg tacgcggcga tgaccctgct ggcggcgggc
     8941 ggggtggccg tcgccgtctc gctgtgggtc cggccgccgg ccggcctggt cccggccgcc
     9001 gaccggctgg cggtggggct ctgcacggcc ttcctgctgg ctccggcggg ccggttcggc
     9061 tacctggcgc tgccggtcct cctcagcgtg tgggcccggc tggccgaggc gccctcacgg
     9121 gtggcccccg ccaggagccg cgtcgtggcg gccgggtccg cggcccgccc cgtcctggtc
     9181 ggcggtgacc ggtgagcgcg cggcgtacgg cggcggtggc ggcctcgctg ggctggggcg
     9241 cgcgcaggct gccgttcgtg gaggacgagg tggaggggct cggcgcctgg gtgcggcccg
     9301 gcgcggcctg cctggacatc ggggccgagt acgggctcta cacctggatg ctgtcggcgc
     9361 tcgccgggcc caccggacag gtgcacagcg tggagccgct gcccgggccc agtggctggc
     9421 tgcgtaccac cgcccggctg ctcggcgccc gcaacgtgac ggttcaccgc acggcgatcg
     9481 gcgaccgcac cgggcacggc acgctgagcc tgccggtccg ccggggcctg ccggtgcacg
     9541 gccgggcgta cctggtggag ggcagccgtg gccccgggcc caacgcggag ttccataggg
     9601 cccgttcggt gcgcaccccc gtgcggacgc tcgaccagct ggtccgggac atagggctgg
     9661 agaagctctc cttcgtcaag gccgacgtgg agggcgccga actggccgtg ctgcgcggcg
     9721 gctcggccac gctgcggcgc caccggccca cgctgctcct ggagatcgag cggcggcacc
     9781 tcacgaagta cggaggcgac ccggccgagg tcctgagcca cctggggagt tacggctacc
     9841 gcgcgcaccg cagacagcac ggccgctggg tacccgcccc ctggatcacc gaggactgcc
     9901 gcaactacct cttcaccgcc tgaccgcccc gtcccccccc ccgtcacccc gtgaggcagc
     9961 gaccacccat gaacaccacc ctgatcgtca ccaacgactt cccgccgcgc caaggcggca
    10021 tcgagacgtt cgtgcacgcc atggcgacac gcgtccccgg caacgacgtg gtcgtctaca
    10081 cctcctccga accgggcgcc gccgcctacg acgccacgct gcccttcccg gtgatcaggg
    10141 accccagccg gatgctgctg cccacccccc gcgtcacccg tcaggccctg cggatcgccc
    10201 gtgaacacgg ctgtgaccgg gcctggttcg gggcggcggc gccgctcgcc gcgatggccc
    10261 ccgcactgcg gcgcggcggg ctgcgccgcc tggtcgccac cacgcacggc cacgagatct
    10321 ggtgggcccg cacccccggg gcacgccagg tgatgcggcg tataggggag aacgtcgacg
    10381 tcgtcaccta cctgggcgag tacacccggc ggcgcatcgc gcccgccctc gggccgcgcg
    10441 cccggctcgc ccggctggtg ccgggggtgg acgcggcgga gttccggccc gcgcccggcc
    10501 agggccggca ggtgcgcgaa caccacgggc tggtgggccg caaggtcgtc ctttgcgtct
    10561 cccggctggt gacacgcaaa ggccaggaca cgctgatacg ggcgctcccc cgcatccgcc
    10621 acacggtgcc cgacgcggcg ctgctcatcg tgggccaggg cccggaccag gagcggctgc
    10681 ggaagctggc ggaccggtac ggggacggcc acgtcgtctt cgccgggggc ctggaccacg
    10741 cgtcgaccac cgcctactac gcggccgccg acgccttcgc catgccgtgc cggacccgca
    10801 aggcggggct ggaggcggag gggctgggca tcgtcttcct ggaggcggcc gccagcggcc
    10861 tgcccgtcgt cgtcggcgac tcggggggcg cgccggacac ggtgctggac ggggagacgg
    10921 gcacggtcgt cgacggcagc gacccggtcg ccgtcgcgga cgccgtcacg ggggtcctcg
    10981 tcgatccggt gcgggccgcc accatgggcc aggccgggcg gaactgggtg gaggaccact
    11041 ggtcctggga ccggtcggcg gaccgcctca accagctgct gacccccggc acggaacggc
    11101 tgccgagccg cgcctcggag tgatccgccg cccccgcccg gcccgtcggg tctccgggcg
    11161 gggcaggcac ggggctcacg ggggctcagg cggcggggtc ctggcggcgg aggtgggcga
    11221 ggaccgcgag aacgcgccgg ttgccctcgg ccgggtccag ctccagcttc atgaagatgc
    11281 tgctggcgtg cttgaccacc gacgcctcgg tgatggtgag ccgctgggcg atggcctggt
    11341 tgttgaggcc ctccgccatc accgcgagca cctcccgctc gcgcggggtg agccgctgga
    11401 gcggcttgtc ggcggtgccc tgctgcagca gcacccgcac cacctccggg tcgatcacgg
    11461 tctgcccgga ggcgacccgg tcgagggcgt cgaggaaatc ggtgacctcc ccgacccggt
    11521 ccttgaggag atagccgagg ccgcccgcgg ccggggagcc gctgagcaac tgggtggcgt
    11581 aggcggtggc gacgtactgg gagagcacca gcaccggcag ggaagggtcc gcgcggcgca
    11641 gctccagggc ggcgcgcagt ccttcgtcac ggaagccggg cggcatccgc acgtcggtga
    11701 tgaccacgtc gggacggtcg gccgcgaccg cgcgggccag ctcctcggcg tcgccgacgg
    11761 cggcggtcac ctcgtggccg acccgggaga gcagttcgac cagtccggcg cggagcagga
    11821 cggcgtcctc cgccagcact acacggagca cggcacctcc acccggagct gcgtgggacc
    11881 gccgacggga ctggtcacga tgagcctgcc tttcagaatg gccacccggt ccgccaatcc
    11941 ttgcagaccg gcgccggcct cgggatcggc gccgccgtgg ccgtcgtcgg tgacgagcag
    12001 gacgagggtg tcgtcccgca gcctccccac gacggacacc tggtcggcgc cgctgtgctt
    12061 ggaggcgttg gtcagcgcct ccgtgacggt gaagtacgcg gtcgtctcca cggcggacgg
    12121 cagccggtgc ggcaggtcca ggtcgacgat gacgggaacc gggttgcgca gggcgagttc
    12181 ggcgaccgcg gcgggcagcc cgtggtcggt gaggacctgc gggtggatgc cgcgtaccag
    12241 ggaacgcagc tggtccaggg cctggcgggc ctcgtccctg gcccggctga cgagaggggc
    12301 cgcgcccgag tcctggccgc gcagctccag ttcggcgagg cccagcgtca tggtgagggc
    12361 gacgagctgc tgttgggcgc cgtcgtgcag gtcgcgttcg atgcggcgcc gctcggcctc
    12421 gaaggcgtcg accaaccggg cccgggaccg ggtgagttcg atgacccggc tgctgaagtc
    12481 ctcgtcgcgg gcggcgagca ggaactgggc cgtccgcacc tggaccccgg cgagcagccc
    12541 gcccgcgtac gccgagacca cgaggccgac cagcccggcg gcgctgccgg gcagggccgc
    12601 gacggggtcg gagaggggct gcccgggcac cagcatcacc gtgtcggggg cgatcgccca
    12661 gacgatgacg ggcgtcgccg tgagaatcag cgacagcccc agcagcgcgg cgaagccgat
    12721 ccccgtcgcg gtgaagacga cccccagcag caccgtgtag gccagctccc gccaggtcgc
    12781 ccgctcccgc agccgggtgc gcagccacgg cagggcgctc gtcccgggca gcgagccgtg
    12841 cgggtcgagc agcggttccg gctcgaccag ccgcagcctg cgccgctcca gggccgcgac
    12901 gggtatgccc acgacggcca gggtcagcag gaccagcagc ccgacgccca ccaccgacag
    12961 gcccacgccg accagcagca gggcggcgca cacgaacagc accacggggc ccacgaccag
    13021 gccgctcagc aggaaggccc aggagcgcag gggccaggcg ccgaacagga agcgcacggg
    13081 acgccgtcgc atggcctccc agacggcgac ggtcatggtg cgggtccctc cggagccgtg
    13141 gcgcgggtgt gtgcaccggg aactctaacg gcccggaggc gtacgccgac ggtagggaaa
    13201 accctccctc cgacactcgc cgcagaccca ctgccccgag ccctcgtctc tgctggactg
    13261 ggaccatgcc actgctcacc gacattcagc tccccgccgt ccagctcgcg gccgtctcca
    13321 agagctatcc cagctcggcg ggtcccgtcc ccgtgctgcg cgaggtcagc ctgggctttc
    13381 cgcaacgggc actgaccgcg gtgatgggtc cttccggttc gggcaagacc acgctgctga
    13441 actgcgcggc ggggctcgac aagcccgaca ccggcaaggt cctgctcggt gagaccgacc
    13501 tggcggcctg cggcgaacgc gagctgaccg tggtgcgccg cagccgcatc ggcttcgtct
    13561 tccagcagtt caacctgctg cccatgctga ccgtgtacga gaacgtggcg ctgccgctgc
    13621 ggctgcagcg cgggcgggtg cgccgggagc gggtcatgga ggcgctgcgc caggtggggc
    13681 tggaggacaa ggcggggcgg cggcccgccc agctctccgg cggccagcag cagcgggtgg
    13741 cgatcgcgcg gaccctggtg gccgagccgg agatcgtctt cgccgacgag ccgaccggct
    13801 ccctggaccg caagagcggg cggcagatca tggagctgct gcgcgacacg gtcgaccggg
    13861 ccgggcgcac cgtggcgatg gtcacccacg acccggccgc cgccgcctgc gcggaccggg
    13921 tggtgttcct ctccgacggc caggtcgtcg gcaggctcga ccacccgacg gccgaggcgg
    13981 tcgcccggca gctcagcctg tgggagcggt gatgtggcgc atctcggtgc agtcggtgcg
    14041 ccactactgg gccctgttcg cgggcacctt cgtcgcgctc gcgctcggcg tcgcgctgat
    14101 cggcgtctcg gcctccgcgc tcgcggcgac ctgggcggtg gacgcgacgc cggacggctc
    14161 cgccccgtcg gtgaccctga aggacggcac cggcgcggcc cgcaccctct ccagcggcga
    14221 cctcgacatg ggcggcgtgc agagcgtgct ggcgatggcg ggggtggtgt cggcgttcgt
    14281 gacggtcttc gtcatcgccg ggacgtgcgc cttcggcatc gcgctgcgcc gccgcgacat
    14341 ggggctgctc cggctggtgg gcgcgggcgg gggccaggtg cgccggatgg tgctcggtga
    14401 gtccctggcg gtggcggtgc cggccgcggt ggccggctgc gcggtggcgg cggtggcggc
    14461 gccgctcgcc gtggaggcgc tgaacgggac cgggctgtcc cctgtcgacc tgcggccggg
    14521 cccgctgctg tggccgctgg tgttcgcggc cggcagcggt ctggtcatcg ccgtgctggg
    14581 catgctggcc gcctcgaagc gggccgcgcg ggtgcggccg acggaggcgc tgcgcgaggc
    14641 ggacctggac tcgcgcacga tgaccgcggg gcgggccgtg accggcgtgc tggccctgct
    14701 cggcggtgcg gtgatggtgg ccctcgcacc gggttcgggc accgaggcgg cgacgccgct
    14761 ggcgctcttc ggcacgatgg cgctggccgt cgcggccacc ctgctggggc cgctctacct
    14821 gccgccgctg ctgcgggtga tggcgctgcc gctgcgctgg gcggacccgg tggcggggcg
    14881 gctggcggcg gagtcggtac gtacctcccg gcggcggacc gcttcgctgg tcgggccggt
    14941 gctggcgatc ctcgcgatcg tcggggtctt caccacggtg ctctccacca cgggcgcggc
    15001 gacctcggcg gacgaccggg cgcggaccac cgcccagctc gtggtcgagc ccgccgggga
    15061 cggcggctcg ctggaccagg aggcggtgga ccggctgcgc gaggacccgc gggtggccgc
    15121 ggtgtcggcc ccggcgccgc tggagatcgc ggtggcggga ccacactcgg cgtggaagga
    15181 gcaggcggcg ctggccgacc cggtggcgct ctcccgtacg caccggatca ccgtggtgga
    15241 cggctccctg aagccgctgg agccgggcac ggtggcgatc tcgcgggagt tcgccgagtg
    15301 gtacgggcac cgggcgggct ccacggtcac ctacggcctg ttcggcggcg agccggtgcg
    15361 ggcgaaggtg gcggcggtgc tggacggcgg ctcggcggtg ccctcggtgg tactgccccc
    15421 ggacacccgg ggggccaccc ccgcgccggc cccggagcgg gcggcggtgc tgctcgacga
    15481 gcggggcgcc gcctccgccg gggcggccgc cgcccagctc accgagcggc tcggcgccga
    15541 ccgggtgcgg gtgctgccga ccgagacgtg gttcggccgg agcgcgaccg accaggaccg
    15601 gctgaacaac ctggtgctgg ccgtcctgac cgtgcccgcc tcgctgtacg cgctgatcgc
    15661 ggtggcgagc accctggtca tgtcctacag caggcgtggc cgggagatca cggggatgcg
    15721 gatgatcggc gtcagcgcgg gccaggtccg gcggatggcg ctgtgggaga ccctggcgac
    15781 cacgacgctg gggacgctga tcgcggcggc ggtggtggcg tggggcgtcc gcgcctacca
    15841 gggttcgctg agcgtcttcg gcggcggggc tccgctgagc gtgccctggg gaatgctcgg
    15901 cacgctcgtg gcggcgtgcg tcctggtggg cgtggtggtg agcctcgccg cgaccgggcg
    15961 gctcctgcgg cgggtcagca ccgcctcgac ggccacgcgt cagtaacgga tgccgcctca
    16021 cctcgtgcgg tgcgccggcg cccggctcgc gccccggcgc accgggtgcc gtggcaccgc
    16081 accggggttt cgggaagtcc cggcggggcc tgacgtcctg accgcgccgg ggcacatccg
    16141 cgcgccatcc gctccgtggt caccgctgtc ccacgtagcg gtatccggcg tggcgcgcct
    16201 atgctgacag ccccacacca ctttccctgc accattcggt ggcatccgtc cgccagttgc
    16261 cgggcacagt cctaactagc gggagtctcc atgcgcgtcg cgatcgctga ggattccgcg
    16321 ctcctgcgcg cgggaatggc gaggctgctc gcggacgagg gcattgacgt catcgcttcg
    16381 ctgggcgaca cgacggagat tgtggaagtg gtgcggaagt gccggccgca cgtggtcatc
    16441 atggatgtcc ggatgccgcc gacccacacc gacgaaggca ttcgcgccgc cgtcgagatc
    16501 cagcggatgg acaccggcac ggccgtcctg ctcctctcgc agtacgtgga gcccacgtac
    16561 gccgaggaac tggtgcgtga ggcaccggcg ggtacgggtt acctgctcaa gcaacgggtg
    16621 ggcgatttcg cggagttcct ctccgctctg caccgggtcc gtcagggcga gaccgtgctg
    16681 gactcggaca tcttcaagca gttcgtggga agtccgcgcg agaaacacgc gacggaattg
    16741 ctcacccccc gagaacgcca ggtactggaa ctcatggcga ccgggctgac gaacagcgga
    16801 atcgtcaacc gcctcggtat atccgagcgt gcggtggaga agcacgtgac ctcgatcctg
    16861 ggaaagctgc gcatcgccaa ctcgggcgag aaccacaggc gggtgctggc cgtcctgaac
    16921 tacctacggg gaatcgaaag actccacgac agatccgaat gacgtgcggt gggtgctccg
    16981 gtgaagttct cgacctccta ccgggtggcg gccggcctca tctacctttc catcggcagc
    17041 ctggtggggc tgctgctggc cccgctgctc ctcctctcac tggtactgcg cctcgcctcg
    17101 tggctgccgc tggtcgccgt acccaaggcg gtcctcctgt gcgtccgcgc cgggtcggcg
    17161 gtgggccggt ggcgcgcggg cgggcgggcg cccggccccc ccgggcggga cagcccgatg
    17221 cgggaggtgc tgcggcagct gccggcccgg atggcggtgc tgcacgaggg gctctcgttc
    17281 agcctgccgc tgctgcgggc ggtcgccgac ctggagcggc tgctcgccca ctcggtcgtc
    17341 ggtgacaacg gccagcccga cccgctgcgg ccgacggcca agacggaacc ggaggaacgg
    17401 ccccgggcgg gctgggacga catccgctac gtcggcctgc tgctgctcgg cacggtgtgg
    17461 ctgctgccgc tggccgcgct ggcggtgccc gtggtggtct tcgtggtgac gctgccgctg
    17521 ggcccgcccg agcagttggc cttcggccct ggcaacacac tgacggtgtc gggccccgtg
    17581 acccgggtga cggtggctct ggccgccgcc gcgctcttca cggtactgat ggggctgctg
    17641 ctctggatgg gccggctgcg ggcccggatg gtgcgttcca tcctgagccg catcgacgag
    17701 gcggaggcgc accgccgcga ggaggccgcg gagcgccggc gcatcgccgc gctgcgggtc
    17761 aacgacgccg actaccgccg cctggaacgc gatctgcacg acggggcgca ggcacgactg
    17821 gccgtcattc tcatgcatct ctcactcgcg aaacaccggc acggagaaga tgccgggcat
    17881 ctgcggtacg tgatcgagga aacgcacacg gaaataggaa aggcgctgga cgatattcgc
    17941 gatctcgtcc ggggagttca gccgcccatt ctcagcgacc gtggcctgga ggccgccgtg
    18001 accgccttga ccgagcgatt tcacgttccc gtggaagtgg acagcggtct cgggcggcgc
    18061 cccgatgtac gggtggaagc gaccgcttac tacatcgtgg ccgaatgcct ggccaacacc
    18121 gtgaagcacg cccgcgccac ccgtatccgc gtcacgctgg aggagcacga gaaccacctg
    18181 gccgtctcgg tgaccgacaa cggcaccggc ggcgcctccc tctcgggcgg aacgggactg
    18241 cgcgggctgg acgaccgggc cgccgcactc aacggccggc tggacgtcag tagtccaccg
    18301 ggtggcccca cgacggtgac cgccaccctc ccgtggtcgc tgcaccccct ctgagctgcc
    18361 ctctttcctc acaccgaaag ctcttgccgt tcaacgaaca ggtgatcgaa gatggggtgg
    18421 tacggctagc cgcacccctc ggggtacggg tagccgtacc ggcggagttc gacaaggggg
    18481 gaatcttgga agcggacctg gcggaggatc tgctgcgcac gctcacccgt gcgcacgcga
    18541 tccctggagc acagctcacc gtcctccggg cgggccggag cctgtcgctg gccaccggag
    18601 tgagaaggac cggcgtcgcc gatccggtca ccacggaaac ggctttcgcg ctgggctcgg
    18661 tgaccaaggc gttcaccgcg actcttgtcg gacagctggt cgccgacggc gaactcgaat
    18721 gggacgaccc cgtcgcggat tacgtggcgg aattcgacaa cgcggtggac gaggcgttct
    18781 ccgagatcac cctgcggcac ctgttgagcc acaccggcgg actggtggcc gaccacgaga
    18841 cggacgacgt ggcggagact tctctggccc gttacacggc gagtgtttcg gcggccaccc
    18901 gcacactgca ccggcccgga tcgtgcttct cctacgcgaa ttccggatac aacatcctcg
    18961 gccgcaccgt cgaagccgtc accgacatga aatggcaggc ggccctcgcc aacctggtgc
    19021 tgcgcccgct cggcatcgac ccggtcttcg tgcacgacgc gcccggcggg cagcgggccc
    19081 tcgcccagtg ccacacggtc cgccccggcg agaaccgctc ggccacgccc gtcggcctct
    19141 tcctgccgcc cagttgggcc ccggcgggcg gactggccgg cagcgcggac gacctggccg
    19201 ccctcgccac cctgctcctg ggcacccacc cggacgcggc ggagctgctc cccgaggagc
    19261 agcgcaccga gatgtgcgcc cggacacccg aggccgacgc cttcggcatg gccgacgcct
    19321 ggggcctggg cctggcccac cacgtctcgc cggacggggt gtggctgggc cacgacggca
    19381 cggtcgacgg cggcacggcc cacctgcggt tccggcccgc cgacggcacg gtggtggcgc
    19441 tgaccaccaa cgccaccacc ggcaccgcga tgtgggccga gctggtcgac gccctgcgtg
    19501 agcggggcgt tcccgtcggc gaccaccgtc ccctcgccgc caccacgccg ccgctgagcg
    19561 ccggtcccgg tcggctcgac ggcgactacc gcaacggcga cacggtgttc cgcgtgcgca
    19621 ccgccgagag cggcgtgccg gtcctgaccg acgccaccgg cctcgtcgcc gacctgacgg
    19681 tccacgagga cctgaccttc accgcgcgtc ggaccgacac cgacgtcgcc ccctacaccg
    19741 gccggttcgt cacggaccgt gcctcgggcg agattcacct catgcagctc ggcggccgcg
    19801 ccgcccggcg gaccgccgct ccgtagccgc tccctctccg cggccgccct ggacggggcg
    19861 cccgcgcgcc gacgcccggc gtccgccgtc cggcctcttc tcctcttctc ttctcttctc
    19921 ttcttccgac gttcccgtcg gcttccggca ccctgccctg ccctcccctg cccggaagcc
    19981 gcttccctgg aggtacacac gtggttcgcg ccgacgcgcc ggtgaaccgg acggtccccg
    20041 ctcagaccga cttctggcgg gcgaggctgg acggtgtccc gccgctcgac ctgcccaccg
    20101 accggccgcg tccggtgatc cggtcgagcg gcaccgccac ccacgagcgc gagctgccgg
    20161 cccccgccgc cgcggccctc gcggagctgg gccggagcca ctccaccgcc cccaccgcgg
    20221 tcctcgccgc cgccgtcacc gccctgctcg cccgctactc cggccaggag gacgtcgcgc
    20281 tcggcacggt ctccccgcgc tccggccaca ccgtcgtcgt ccgcaccgcc gtcgaaccgg
    20341 ccgcgccctt cgccgccctg ctggacgaca ccggccgcgc cctggacgag gcgctggccc
    20401 acgacggcgt cccgttcgcc gacctcgtcg aggcgctggc tcccgagccg gacaccagcg
    20461 tcaccccgta cgtccaggcc atggtcgccg tgctggacga actcggtccg gcgcagcggg
    20521 acttcgaccc gctggacctg tcggtggaga tcgccgggac ccggctgcgg gtgcggcaca
    20581 gcaccgccct cttcgaggag gcgacggcca ccaggctcgc cgggcacctc accgtgctgc
    20641 tcgccggggc ggcggccgac ccggcgacgc cgctcagcgc gctgccactg atcaccgacg
    20701 acgagttcac cgaggtcgtg cacgtctgga acgacacggc gcgcgaggtc ccggccggca
    20761 ccttccccga gctgttcgcc gcgcgggtgg ccgagcggcc cgaggcgacc gccgtcatcg
    20821 acgagagcgg cccggtcagc taccgggaac tggacgagcg ggccaaccgc atcgcccacc
    20881 atctcctcga actgggcgcc ggaagcgacc agttgatcgg cctctgcgtc gagcgcggcg
    20941 cggccatggc ggccgggctg ctcggcatca tgaaggcggg cgccgcctac ctgccgctcg
    21001 atccggccta cccggccgac cggctggcgt acatgctcca ggactccggt gtgcgcgtcg
    21061 tcgtcaccca gcgcgagctg cgcgaccggc tgcccggcac cgacgcgacc ctcgtggacc
    21121 tcgccgccga ccgggcggcg ctcgacgccc gcccggcaac cgcgccggag accacgccgg
    21181 tcgccgagga cctggcgtac gccatctaca cctcgggctc caccggtcgt cccaagggcg
    21241 tcctcgtctc ccacgcgggc atcggcaacc tggccgccgt gcaggcggag gcgttcggcg
    21301 tcaccggcga cagccgggtc ctgcagttcg cctccgccag cttcgacgcg gcgttctggg
    21361 agatgtgcat ggggctgctg accggcgccg ctctcgtcat gggcgccaag gagacgctgg
    21421 cgcccggcga accgctcgcc gcctacgccg cggagcacgg cgtcacccac gccaccctga
    21481 cgcccgccac cgtcgccgtg ctgcccgagg gccgcggcct gcccgagggc gccacgctcg
    21541 tcgtggcggg cgaggccagc acggccgacc tggtcgcccg ctggtcgggc ggccgccgca
    21601 tgatcaacgc ctacggcccc accgagacca ccgtctgcgc cacgatgagc cgcccgctca
    21661 gcggcgccgt ggtgccgccg atcggcaccc cgatcgccaa cttccgggcg tacgtcctgg
    21721 acgacgccct gcggccggta ccggcgggcg tgcgcggcga gctgtacctg gccggacccg
    21781 ggctcgcccg gggctaccag ggccggcccg ggctcaccgc ggagcggttc gtcgccaacc
    21841 cgtacggggc gcccggcgag cggatgtacc gctcggggga cgtggcccgc tggagtgccg
    21901 gcggtgacct ggagtacctt ggccgcgccg acgaccaggt caaggtgcgc ggcttccgca
    21961 tcgagctggg cgagatcgag agcgccctgg cccttcaccc gggcgtcgcc caggcggtcg
    22021 tggtcacccg caacaccaac ctgatcgcct acgtcgccgc cgccgggaag cagcgcccca
    22081 cctccgacgc cctgcgcgcc ttcctcgccg agggtctgcc cgaccacatg gtgcccgcca
    22141 ccgtcgtcgt cctggacgcc ctgccgctta cccccaacga caaggtggac cgcaaggcgc
    22201 tgcccgaccc cgccacggtg cgcgagagcg aggcggccac cgaggacgcg ccgcgcacgg
    22261 cggtcgagga gacgctggcc gccatctgga ccgatgtgct cggcgtcccg cggatcggcg
    22321 tccacgacga cttcttcgcg ctcggcggca actcgatcct ctccgtccgc gccgtctccc
    22381 ggatgcgcgc ggcgctgggc gtcgccctgc cgccccgcgt gctcttcgac accccgacga
    22441 tcgccctgct cgccgcctcg gtggcacccg aggactccgg cgaggactcc gccatcccgc
    22501 tcgtgccgcg cgacggcgcc ctgccgatgt cgtacggcca gcaacgccag tggttcctcc
    22561 acgacttcga cccgacgggc gccgagtacc acaccgccac cgggctgcgc ctgaccggca
    22621 ggctcgacac cgaggcgctg cgcggcgccg tccaggacct gaccgcgcgc cacgagtccc
    22681 tgcgcaccac cttcggcgtc gtcgccgggc gcggcgtcca ggtggtccac ccgcagctcg
    22741 cgcccgagtg gcggaccgag gacgtctccg ccgtcgacgg ctcgctgcgc gaggaccggc
    22801 tgcgcgagct ggtccgcgcc cagacggccc gcccctacga cctgacggcc gggccgctgg
    22861 tgcgcgtgct gctggtccgc ctcgccgacg acgagcacat ctgcgtcctc ggcatgcacc
    22921 acatcgtcac ggacggctgg tccaccggca tcgtcctgcg cgagctgggc gagttctacg
    22981 ccgcgcgcac cgaggaccgc gccccggagc tgcgcgaggc cgccgtgcag tacccggact
    23041 tcgccgcctg gcagcgcggc cgtctggaga gcggcggcct gctcacccgg caactggagt
    23101 ggtggcgtgc gcagctggac ggcatcaccc cgctggaact gcccaccgac cggccgcgcg
    23161 ccggggtccg ctccaccgcc ggcgccacgt acaccttcgc cgtgcccgcc accaccgcct
    23221 ccgccgtcaa ggagctggcg cggcgggagg gcgccaccct cttcatggcg ctgacggcgg
    23281 cggtcaaggc cgtcctcgcc cgctggtccg ggcaggagga catcgcggtg ggcaccgcct
    23341 cctccggccg caaccacggc gacctggagg agctggtcgg ctacctcgtc aacacggtgg
    23401 tgctccgctc ccgcgtggac gccgcgatgt cgtacgggga gctgctggcg cagctcaagg
    23461 agaccgccct ggaggcgttc gcccacgagg acgtgccctt cgagcggatc gtggacgcgg
    23521 tgggcgcggc ccgcgacaac agccgcaccc cgctcgtcca ggccatggtg gtgctgcaga
    23581 acgcgcccgc cgaccgcgcc cggctgcccg gtctcaccgt caccgaccac ccggtgcacc
    23641 gcgaggcggc gccgttcgac ctgacggtgg agttcttcga gggggaggac ggcctcaccg
    23701 cccaggtcgg ctacagcacc gccctcttcg acgaggcgac cgtcgcccgg ttcgccgggc
    23761 acgtgacgac ggtgctggcg gccgccgcgg ccgagcccgg ccgtgccctc gccaccctgc
    23821 cgatgctgac cgacgccgag caccaccagc tcgtccacgg ctggaacggc gccaccgtcc
    23881 ccccgctgcc cggcaccttc cccgagctgg tcgccgagag cgcccgccgc cgccccgacg
    23941 cgccggccgt ggaggacacg cacaccgcgc tgagctaccg gcagctggac gagcgggcca
    24001 accagctcgc ccaccacctc cgttcgctcg gtgccgggcc cggcaccctc gccgggctct
    24061 gcctggagcg cggggtggag accgtcgtcg gcctgctcgg catcatgaag accggcgccg
    24121 cctacctgcc gctcgacccg ggctacccgg ccgaccggct cgccttcatg ctccaggact
    24181 ccggggcctc cctcgtcgtc acccgctccg agctggccgg gcgcctgccg gacaccggcg
    24241 cggtcgtcgt cgacccggcc gccgtcgccg gactccggga cctgcccacc accgccccca
    24301 cgccggggcc acgcccggac gacctcgcgt acgtcatcta cacctcgggg tcgaccggca
    24361 ccccgaaggg ggtgctcgtc ccgcaccggg gcatcggcaa cctggccgcc gccgagatcg
    24421 agcggctgga ggtgaccgag gagagccgga tcgtccagtt cgcctcgtcc tcgttcgacg
    24481 gcgcggtcat ggagatcctg atggcgctgc ccgcgggcgc caccctcgtc ctgccgccgc
    24541 acgggccgct ggtcggcgag gcgctccagg acttcctgtc cgcacgccgc atcagccacg
    24601 ccctgctggc gccctcggcc gtcgccaccc tgacccccga cgggctggag gggctgcgca
    24661 ccctggtcgt cggcggcgag gccagcaccg gcgacctggt ggcccgctgg tcgccgggcc
    24721 gccgcatgat caacgcgtac gggcccaccg agtccaccgt ggtcgccacc atgagcgccc
    24781 cgctcaccgg cggcgccgtc ccgccgatcg gcaccccgct gcccaacacc cgcgtccggc
    24841 tgctcgacgc cgcgctccag ccggtgcccg ccggcgtgcc cggcgagctg tacatcgccg
    24901 ggccgcacct ggcccggggc taccacgggc gccccggcct gaccgccgag cggttcaccg
    24961 ccgacccgta cggcgcgccg ggcgagcgca tgtaccgctc cggcgacgtg gcgcggtggc
    25021 gggccgacgg cagcctggag tacctgggcc gcgccgacaa ccaggtcaag gtgcgcggct
    25081 tccgcatcga gctgggcgag atcgagaccg ccctcggccg ccacccggac gtacgggacg
    25141 cggtggtcgc cgtccaccgc gacgggacag gaaggcagcg gctggtcggc cacctggtga
    25201 ccgaccgcga gctgaccacc ggcgaactcc gctcccacct ggccggttcg ctgccggact
    25261 acatggttcc cggcctgtac gtgcggctgg agcggctgcc gctcaccccg agcggcaagg
    25321 tcgaccggcg ggcgctgccc gagccggact tccgggcgga gcgcggcggc gccgaccaca
    25381 ccccgccgcg caaccgtgcc gaggaggtgc tggccggggt ctgggccgag gtgctcggga
    25441 tcgaacgggt cggcgtccac gacaacttct tcgacctcgg cggggactcg atcctctcca
    25501 tccaggtcgt ctcccgcgcc cgccaggccg gcatcctgct cacctcccgg ctgctcttcc
    25561 tccaccagag cgtcgccgcc ctcgcggagg tggccgggac ggtcgaggag gcggccacgg
    25621 gcagcggccc ggccgaggtg acgggcgagg ccctgctcac tcctgtccag gactggttct
    25681 tcgccgagca caccgtcgac ccggaccact acggcatgtc cgcccaggtc gaactggcgc
    25741 ccggcaccga caccgccctg ctggagcgcg ccctcgccgc ggtcgccgcc cggcatgacg
    25801 ccctgcggat gcgctacacc cgccaggacg acggccgttg ggtccaggag tacggcaccg
    25861 ccccggccca gccactggcc gtacgcgacc tctccgggct tgcggcggaa cagcgggagg
    25921 ccgcgctgca cgaggccgcg tcggcggcgc agcgttccct ggacctggcg ggcggcggcc
    25981 tcttcaaggg cgtcttcttc cgcctgggcc cctcccagct cccccggctg ttcctggccg
    26041 tgcaccacct ggtgatggac ggggtctcct ggcgcatcgt cctggaggac ctcgccaccg
    26101 cctacgcgca gctcgccgag gggcgccccg tcgacctggg cgcccggacc agcagctacc
    26161 agcagtgggc ggaccggctc accggccacg tgcgctccgg cgccatggat cacgaacttc
    26221 cctactggca ggcggaatcg gcgcacatcc ggccgctgcc ccgggacgcc ggcgccgacg
    26281 aggcgccgga ggccaacacc ttcggcgccg cggcgaccgc ctccgtacgg ctgagccgcg
    26341 ccgagacgcg ggccctgctc cagcaggtgc ccgcggcgta ccgcacgcgg atcaacgacg
    26401 tgctgctgac cgcgctcggc cgggtcctgc gcgactgggc cggggagccg gtcaccgtgg
    26461 ccctggaggg ccacggccgc gaggagctgt tcgacgacgt cgacctctcc cgcacggtcg
    26521 gctggttcac caccatccac ccgttccggc tggagcttcc cgaggcaccg gacggccccg
    26581 acgactgggg gcgctccctg aaggccgtca aggagcggct gcgggccgtg cccggccacg
    26641 gcatcggcca cggcgcgctg cgccacctct ccgagccgga caccgccgcg caccgcgccc
    26701 tcgcgggcgc tccgcacccc gagatcagct tcaactacct cggccggtgg gacggtgcca
    26761 ccggcaccga agggctggtc cgcacgcggc tcgcggagcg gctcggcgcc gaccaggcgc
    26821 ccgcccagcc ccgcccgcac ctgatcgacg tggtggcggc cgtcggcgac ggggaactgc
    26881 gcgtcgactg gatccacgcc ccggccgtcc accgcaccga gacggtccag cggctcgccg
    26941 acgccttcct cgccgcgctg cgcggcgtgg tggagcactg cctgcgcccg gagaacggcg
    27001 gggccacccc gtccgacttc ccgctggccc ggctcgacca ggcggcggtg gaccggatca
    27061 ccggcggcgg ccgcgacgtc gaggacgtcc atccgctcac cccggtgcag agcggcatgc
    27121 tcttccacac cctgtccacc ccgcgcgcct acaccgagca gatgaccttc gagctggacg
    27181 gcgtcgacga cccggcgctg ctcgccacgg cctggcagcg ggtcgccgac cacgtcggtg
    27241 tcctgcgcgc ctcactggag tggcgggagg tggagcggcc gctgatggtg gtccggcgcc
    27301 aggccgagct gccggtgacc cacctcgact ggcgtggcct gcccaccgcc gagcaggagg
    27361 aggccgtacg gcggctcctc gccgaggacc gcggccggcc cgtggacctg accgtcgcgc
    27421 cgctgatgcg gctcaccctg gtgcggctga cggacaccac cgtccggctg gtgtgcgcct
    27481 tccaccacat cctgctcgac ggctggtcca ccttcgacgt gctggcccag acccacgcgg
    27541 cctacgcgga gctggccgcc ggccgggagc acccgctgcc cgcccgccgc cccttccgcg
    27601 cctacgtcga ctggctggag cggcaggacc tggccgaggc cgaggcgtac tggcgcgaga
    27661 ctctggacgg cttcgcggcg ccgaccccgc tgcccgccct gcggcacacc gcgccgggcc
    27721 acgccaccgg ctccaccgcg cggctggcgc ggcgcctgga cccggccgcc tcccgcgcgc
    27781 tgttcgcctt cgcccggcgg caccggctga ccgtcaacac cgtactccag ggcgcctgga
    27841 cgctgctgct ggcccggcac gccggggagt ccgacgtggt cttcggcgcg accgtctcgg
    27901 gccgtccggc cgacctgccc ggcgcggact cgatgatcgg catgctcatc aacaccctgc
    27961 cggtccgggt acgcgtcgac gagtcggcac ccgccgccgt ctggctccag gcgctccagc
    28021 gggcccaggt ggaggcgcgg cagtacgagt acgtgccgct cccccgtatc caggcgtgcg
    28081 gcgccgtcga gcggggtgcc gatctcttcc ggaccctggt cgtcttcgag aactacccga
    28141 tggacgacga ggcggccgcc gcccacggcc tgcggctgcg ccgcctggcg ggcaccgagg
    28201 ccaccaacta cccgctcaac ctcatcgcct acgccggcga cgacctcagc tacaccctgg
    28261 cgtacgacgc cgcgctgtac gacgaggcga cggccgggcg gctctgcgga cggctggagg
    28321 cgttgctcgg ctccctggcg gcggccgacg gcgggacacc ggtctccgcc gtggggatgc
    28381 tcaccgaggc cgaggcggag cagaccgtac gcggctggaa cgacaccgcc gaggagctgc
    28441 ccgaggcgtc ggtgccggag ctgttcgccg cccgcgtccg cgaacacccc gacgcggtcg
    28501 ccgtcaccga cgcgggcgag gagctgacct accggcagct ggacgagcgg gccaaccgcc
    28561 tcgcccacca cctggtggcg ctcggcgccg gccgcggctc cctggtgggc ctgtgcctgg
    28621 agcgcggggc gcacgcggtc accgcgctgc tcgccgtggt caaggcgggg gcggcgtacg
    28681 tcccgctgga cccgggctat cccgcggacc ggctggcgta catgatcggc gacgccgggg
    28741 tgggactgct ggtcaccgag aaggccctgc gcgaccggct gcccgcctcc ggggtccggg
    28801 ccctggacct ggacgaggag gccggggcga tagccgcccg gcccggtgac gcggcgcccg
    28861 tgccgtcccc ggcgccggac gacctcgcct acgtcatgta cacctcgggc tccaccggcg
    28921 tgcccaaggg cgtgctgacc ccgcaccggg ccgtggtgcg gctggcgctg gcgagcgggt
    28981 acaccgaggt ccggcccggc gacacggtgg cgcagttcgc ctcgctctcc ttcgacgcgt
    29041 cgacgttcga ggtgtggacg gcgctgctgc gcggcgcacg gctggcggtg cacccgccgc
    29101 acgtgccgac cacggcggag ctcggccggt tcctcaccga ggccggcgtc acccacctgt
    29161 ggctgacggc gggcctgttc caccaggtcg ccgaggacga cgtgacggtc ttcgccgggc
    29221 tgcggcacct gctggcgggc ggcgaccggc tctcgcccga gcactgcgcc cgggtcctcg
    29281 acgcccatcc cgcgctgcgg ctcaccaacg gctacggccc gaccgaggcc accaccttca
    29341 ccaccacgca cgacctgcgg ggagccctcg gcgagggttc ggtgccgctc ggcgcgccgc
    29401 tggccaacac ccgggtgtac gtcctggacg gcggcctgga accggttccc gccggggttc
    29461 cgggcgagct gtacatcgcc ggggcggggc tcgcccgcgg ctaccacgcg cgggccgggc
    29521 tgacggcgga gcggttcacc gccgacccgt tcggcgcgcc gggcgggcgg atgtaccgct
    29581 cgggggacct cgtggcgtgg cggccggacg gcaccctgga gttcctgggc cgcaccgacg
    29641 gccaggtcaa gatccgcggt ttccgggtgg agaccggcga gatcgaggcc gcgctcgtcg
    29701 cccacccgtc cgtcggggac gcggccgtgg tgccgcacac cgaccccggc tccggccgga
    29761 ccctgctggt cggccacctg gtgccggccc agggcgccgt actgcccggt gccgcggagc
    29821 tccgcgcccg cctggccgcc tcgctgcccg agtacatgct gcccgccgcc ttcacggcgc
    29881 tggacgccct cccactgacc gccaacggca aggtcgaccg gcgggcactg cccgacccgg
    29941 acggggcgcg gctggccacc ggcaccgcgt acgaggcgcc gtcctcgccc accgagacgc
    30001 tgatcgccga ggtctggcag gagctgctcg gggccgagcg ggtcggcctg cacgacaact
    30061 tcttcgagct gggcggcgat tcgctgctcg ccctgcgcac ggtgacgcag atcaacacgg
    30121 tcttcggcac cggtctgacc ccccgcaccc tcttcgaccg gccgacggtc gccgaggcgg
    30181 ccgccgaggt cgaggacgtg atcctcgccg agctnnnnnn nnnnnnnnnn nnnnnnnnnn
    30241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    30301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    30361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    30421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnaccaca
    30481 gaacacacac caccccgcac ccccaccgaa cacctcctcg ccaccacctg ggccacagtc
    30541 ctcggaaccg aagaaatcgg catccacgac aacttcttcg acctcggcgg cgactccatc
    30601 ctctccatcc aggtcatctc acacgcccgg cgggcgggtc tccagctcac gtcgaagctg
    30661 atgttcaccc accagacgat cgcggaactg gcctcggtgg tacggcatgc cgagccggag
    30721 acgaccggcg gcgacgtggc ggaggcggtg gccgggcgcg tcgaactcac gccggtccag
    30781 cggtggttct tcgacggaca caccacggac cccgaccggt acgcgatgtc cgtgcacgtc
    30841 gccctggcgc cggacaccga cccggcggtg ctggcacgcg cgctggaggc gatcgtcgac
    30901 caccacgacg ccctgcgcat gcggtacgcg cccgacggcg agggcggctg ggcgcaggag
    30961 tacggcgagc gccccgacgg cctgctcacc gtgcgggaca tcccggccga cggcgcggaa
    31021 gcggccctgc acgacgcggc cgacgaggcc cagcgcgccc tggacctgcg cggcggggcc
    31081 ctggtgaagg gcgtcttcct gcgcacggcg ggggcggaca cgccgccccg gctgttcctg
    31141 gccgtccacc acctggtgat ggacggggtc tcctggcgca tcctcctgga ggacctcgcc
    31201 accgcctacg cccagctcgc cgaggggcgc cccgccgatc tgggcgcccg gaccagcagc
    31261 taccagcact gggcgcggcg gctcaccgat cacgtgcgct ccggcgcgct cgaccacgag
    31321 accggctact ggcgcaaggc gtcggccggc gccgtggacc tgccgtgcga cgggcccgcg
    31381 tcgagcacgt acggggaggt cgcggccgag tccgtcgtgc tggaccggga gacgaccgag
    31441 gcactgctgc accgggcgcc ggccgcgttc cgtacccaga tcaacgatgt gctgctgggc
    31501 gcgctggggc gggtcctgaa cacctgggcg ggcgggccgg tcacggtcgc gctggagggc
    31561 cacggccggg aggagctctt cgacgacgtc gatctctccc gcacggtcgg ctggttcacc
    31621 accatctatc ccgtcaccct cgtcgtaccg gacggcccct ggggcacggc gctgaaggcg
    31681 gtcaggaaga ccctgcgcaa ggtgcccggc cgtggcatcg gctacggcgc cctgcggtac
    31741 ctgcgggagc cggaccaccc ggaccgcgtc gcgctcgcgg cggccccgcc gccgcggatc
    31801 agcttcaact acctgggcca gtgggacagc gccgacggtg gccgcggact cgtccgggac
    31861 cgcctcgacg ccctcggcgc cgaccaggcg cccggggaga accgccccca tctgatcgac
    31921 gtggtcgccg ccgtcagcga cggcgagctg cggatcgagt ggatgcacgc cccctcggcc
    31981 cacgccccct ccaccgtccg ccgcctcgcg gacgacttcg ccaccgccct gcggcagatc
    32041 gccgcagcgg ccggaaactg accgacctac cggaaggctg ctgttgtggc tcgctacgtc
    32101 ttgactgacg ccgagaagaa cgaactggca cggatagcgg acgagttcct cgccgcgcac
    32161 cccgtctggg cccccctgga gtacgtggac gacatccgtg tcgaggccga acggctgccg
    32221 gtcggcgtgc gccggttcct ggcgggcgcc cgtaccgccg aggacgccat cgtcgtggtc
    32281 tccaacctgc cggtcgacga ggacctggtc ccgaccccgt cgagctggca ggtcgcggag
    32341 aaggagggcg cggcggtccg tgaggaactg gtgctgctgc tggtcggttc cgtactgggc
    32401 gacgcgttcg gctggaacaa ccagcagaac ggccggctgg tgcacgacgt ctgcccgtcc
    32461 aagggccagg agaactccct gaccagcgcg agcagtcagc agcaactgac gctgcacacg
    32521 gaggacgtgt tccactcctg ccggggcgac tacgtggccc tgatgtgcct gcgcaacccc
    32581 gacgcggtgg gcaccacggt ggcgctggtc gagtcggtgg agttcgagga gccgctgcgc
    32641 gaggtgctgc accagaaccg gttccgcttc ttccccgacg actcccacca ggtggtgccg
    32701 ctgcacaccg ccgaggcccc ctcggcgctg gaggagcgcc cgcacgaggt cgcctccgtc
    32761 ctcttcggcc ccgaggacgc gccctacctg cggatcgacg ccgacttcac cagcccggtc
    32821 cccggcgacc gcgaggccga gcaggtcatg gtgcaggccg ccgaactgct cgccgacgcc
    32881 gccgagcggg tggtgctcgc tcccggggag gccgtcttcg tcgacaacta caaggtgatc
    32941 cacggccggg acacgttcac cccccggtac gacggcacgg accgctggct caagcgcacc
    33001 agcctggtgc gggacatccg gcgcacctac gtgcggtcga agtcgcgctc ccggctgctc
    33061 ggctgatgcc gggcgggacc gcggagggga gccgcaaggg cggcttcacc ctgctgtggg
    33121 tgagttcggc gttcgccgag ttcgcctaca gcacctccct gatcgtgctg ccgctgatcg
    33181 tcctggcgct caccggctcg ccctcgcagg ccgggatcat cggtttcgtg gacgcggcgg
    33241 cgatgctcct ggcggggctg cccgccgggg ccgtcgccga ccggttcgac cgcaggaccg
    33301 tgatgctgtg gtgccaggcc gccctcgtcg cggtcttcgg ctccctggcc ctgctgttgt
    33361 gggcggacgc cgtctcgctg ccggcactga tcggcctcgc cctggtcaac ggcgcggcca
    33421 ccgccctgac gatggcggcg ggcgacgcca tgatcccgag cctggtggcc cccgaacggc
    33481 tctccgacgc cgtcgcgatg aacgcggccc ggacgtacgc gggtcagctc gccggtacct
    33541 cggcgggcgg gttcctgctg gcgctgaaga acgccttccc cttcgtcgtg gggtgcctgg
    33601 cgcacctcgc cggtctggtg ctgctgctgt tcctgaagcg gcagccgtcg gcccgcccgg
    33661 acggcgaccg ggaccagacg gacgggcggg gactgctcga aggggtccgc tggatcatgc
    33721 gccatccgtt cctgcgggtg gggctggcct gtgccacggc gaccaacttc ttcttcggcg
    33781 tcatctactt catcgtgatc gcgtcggcgc agaccagcgg gatgaacacc ggcctcatcg
    33841 ggctcatggc ggggctgctg ggcgtgggcg gcctgctggg cgccctggcg gccccgctgc
    33901 tccagcgcct gctgagcggc gcccgcccgg tctacgtggt gctgtgggcg ttcgccgtgc
    33961 tcaccgtggg gatcgcggtg ctgcccggca gctggacgcc gggggtgctg ctcggggccg
    34021 tggccttcgc cgcgcccacc gccaacgcgt tcttcaccac gcagcagttg gcgctcaccc
    34081 cggacagcca ccggggccgc gtggtcagcg ccgccgccgt cgcgagcggg ggcggcggcg
    34141 cgatcgcccc gctggccagc ggcatcgtgc tggacctggc cggccgctcg gccgggctgc
    34201 tgggctgcgc ggccgtgatg gcggtcatcg ccctggtgac cacgttgagc ccggccctgc
    34261 gcgacgtacc ggacccggcg gccgtcgatc ctccctcgga cccccggccg gactcccaag
    34321 tggaacccgg cccggttccg ggccgcggcc ccgggaacga gccggaatcg gatgcgtacg
    34381 ccgattcggg gacggaaacg gaatccgcgc cggaatgcgg tgcccgatca gcgcgtgaag
    34441 taagccctgt ccccggaacg ggacggggct cagaacagcg gcaggaaaca tcaccggaac
    34501 cggcacccga caaggtgtga cctcgcggtc cgccggtccc tccctccccc tcccccggac
    34561 gaacaggtaa agacagctca ccatgaccat tgatctggcc aatcccgacc tctacacgac
    34621 ggacgcccgt ttcgagatgt gggaggagta catccgctcg gacgcgaaag tctggagcga
    34681 tcccggaatt tccccgtccg gtttttggtc cgtcttctcc caccgcgacg tctccgccgt
    34741 cctctccccg aaggcgcctt tcacctccga gtacggcatg atgatcggat tcgacgccga
    34801 gcacgccgat cattccggcg ggcgcatgct ggtggtgagc gagggcaact ggcattccgt
    34861 cctgaagagg ctcatcggcc cgttcctctc ccggttgcgc gcccccgagc tgcgctccgt
    34921 gctccacgag gaggtgcgcg agatcgtcga gcggctccgc tcgcaggaga ccaccgacat
    34981 cgcgctgacg gtgggacccc ggctgcccgc cgccatcgtc tgcgaggtga tcggtgtccc
    35041 gctcagcgag cgcgagcacc tgatccagct caccaaccac gctttcggcg gcgaggagag
    35101 cagcttcgac aagatgacgc ccgccgaggc gcacacagag atcctcttct acttccacga
    35161 actgatcgag cgccgccaga aggagcccgg caccgacctg gtcagcgcgc tgctcgcgga
    35221 cgggcggctc agcaccgagg acgtactgat caactgcgac aacgtgctga tcggcggcaa
    35281 cgagaccacc cggcactcga tcaccggtgc cttccacgcc ttccaggcgt tcccgggcgc
    35341 cctcgacacg ctgcgcgccg acccggaact ggccgaccgc gcggtcgagg aggtggtccg
    35401 ctggacctcc cccgccgcgc acgtgctgcg ggtggccacc gaggactgcg agatcggcgg
    35461 ccagcagatc cgcgaggggc aggcggtggt ggcctggctg gcggcggcca accgcgacga
    35521 gcggctcttc gcccacccgc accgcttcgt ggtggaccgc gcccccaacc gccatctggg
    35581 gttcggcacc ggcccgcacc actgcctggg cgcggcgctg gcccggctcg aactgaagga
    35641 actgctgacc cagctcgccg ccgaggcgaa ggccgtcgaa ccgcgcgaag aggtgcgctg
    35701 gatgcgttcg aacctggtgc agggatacag cggtctggag gtctccatgc ggtggcgctg
    35761 acactacgcg cgtcgatata gtctcggacc gatcactggg gggagtgctt cgtcatgctg
    35821 gagatatgcc tgggcgtcga ggatctggcg cgtattcgca tcatcggaac tctgggtacc
    35881 gccttcgaga ctcatctggc ctgggggcag ttgggaaaac agcagcggga cgccctttcc
    35941 gagtggcgcc gcaccgcgcg gatccgattg cgaagagcgg gcgccaccat ggcgaaggcg
    36001 cgttccgcct ctctggtgga aacgctgacc tcgccccttc cgcacgaggg ggacgtgttc
    36061 cacaagatgg cggtcgagcc gttctgggac agaattcagc ggttattgaa agctgaacga
    36121 gattcctgcg gccgggagat gctggccgga ggtgtcgagc acgtcctcaa caaccgccac
    36181 agcgccatcc ggtgggaggc ccccgtgctc cgcgtcgcca acggacggcc gccccggcgc
    36241 acctccctga ccggccaggg cctgacgctc gtcccctccc tcttcgcccc gcacccgttc
    36301 ctgctcgacg acagcgtggg ctggcacgga ctgccgatcc tggtctacaa catcgccccc
    36361 gacacggagc cggccgccgc gctgtggcag agccaggagg gcgagtcggc cctccccgcc
    36421 ctgctcggcc ggaccagggc ggacgtcctg gaggccctgc gcgagacccg ctccacgggc
    36481 caggtcgccg accgggtcca catctccagc ccctccgcca gcaaacacct cacgatcctg
    36541 cgccgcgccg gcttcgtgtc cacggagcgc cgccagaacc tcgcggtcca cagcctcacc
    36601 ccgctgggcg aggccatcct cggctgaaga aacggaagct ccggcatgcc cacatccgcc
    36661 ctcacccggt acaccaagcc cctcgccccc acccgccgcc tggtctgttt tccccacgcg
    36721 ggcggcgcgg ccagtttcta ccgtgactgg cgccggtgcg ccccgccgga ggtggagctg
    36781 atcgccgtgc agtacccggg ccgcgagaac cgcgtgcgcg agccgctggt cgcgacgatg
    36841 gaggagctgg cgacggcgct cgccgaggag ttgctggccc tcccgccgct gcccaccgtc
    36901 ttcttcggcc acagcatggg cgccgccgtc gcacacgaga cgctgctgcg cgtcgagcgt
    36961 tcgggtgcca cccacgtcac tcgtctgtgt gtttccgggc gggccccgcg gcgctcccca
    37021 cgcacctccg cacggacgga cgaggaggtc gtggcggccg tcctggcgct gggcggcacc
    37081 cacgcgacgg tcttcgagga cccggagctg cgcgaactgc tcctgcccat catcgccaac
    37141 gactaccgcc tcatcgacgc ctaccgcccg gtcgccggaa cacccctgct gcgcgcggcc
    37201 gttcatgctc tgaccggtgc cgacgaccct caggtcaccc cggaggaggc cgggcagtgg
    37261 cgcgccgtga cctcgggccg cttcgccctc accgtcctgg acggcgacca cttctacctg
    37321 gtcccggagg ccgagcgggt cgcccgcgcc gccctggacc cggaactgca cgtaccggtt
    37381 tagcggaacg gggatggtcg ggagaagctc cgggccattc ggaggggtgc cggatgtcct
    37441 gatgagcacc ggaaccggaa ccttgtccca tggcccggaa ccgatgcgtc ctcatcctga
    37501 ccctgctcct gtgcaccctc ggcctcgtcg cggccacgct cccgccaccc gaggaacagg
    37561 cccggcaggg ggcggcccgc cacgcccacg cgctgcgcac caccgacccg gccggcgacc
    37621 tggccgacct gcgtccgctc gggcggatgg tgggcgacgc gaaggtggtg ggtctcggcg
    37681 aggccacgca cagctcgcac gagttcttca ccatgaagca ccgggtgctg cgctacctgg
    37741 tcgaggagaa gggcttccgc gccttcgccc tggagacggc ctggagcacc ggcctgcggc
    37801 tggacgcgta cgtacgcacc ggcgacggcg acccgcgccg catcatgcgc gaggagttcc
    37861 aggacacgta cgcctggtgg aacacgaagg agtacctcgc cctcgtcgag tggatccggg
    37921 agtggaacac cgaccacccg aaggaccagg tccgtttcct cggcgacgac ttcgcctacg
    37981 ccggccccga gctgtacgac cgcgtcctgc gctacgccgc cctccaccag ccccgcctgc
    38041 tcccccgtct cgccgagctg taccgcggcc tgcgccccac cacctcgtcg ggcacctaca
    38101 tgaaggagta cctgacccgc cccctcccgg aacgccgcgc cctcgccacc cgcaccacgg
    38161 aggccctcgc cctcctcacc cgccacgcgc cgtcctccgg cccggccgcc gaggcgcgcg
    38221 cctgggccct ccagcacgcc cgcgccatcg accagaccgc ccgcggctac gccttcgact
    38281 tcgacgaccc cgaggacctg cgcgcctcga tgggctaccg cgaccagctc atggcggaca
    38341 acgtcgcctg gtggcacgag cagaccggcg acaagatcct cctctccgcc cacaacagcc
    38401 atctcgccta ccgctccgcc gacccccgct accccaagat gcagggcgcc ttcctccgcg
    38461 accggctcgg caccgcctac ctcagcgccg ccatgacctt cggcaccggc tccttcaacg
    38521 ccacgggccg cgacggcgcc accaccctcc acaccctgaa ggcccccgcc cggaacacca
    38581 ccgaacactt cctgaacagc gtcaccccca ccgactacta cctcgacctc cgcaccgccc
    38641 ccacccccac ccgcacctgg ctctcccccc cccgccccac ccgcaacatc ggcaccgcct
    38701 accccgaacc gccccagaag gtcgccccgg cccactccca cgacgtggtg atgcacctgc
    38761 accgggtcac gggggcgggg ttgctggcca cgcctgagtg aacggagggc ggagggcgct
    38821 gacatggaag gtgttccagg tcatcccggt acgcagcacg acggggagcc ctggaacacc
    38881 agccgctccg cccggagttc acgccccggc tccacgttcc cggagcgatc cgaccaccgc
    38941 gaagaccctt cggtcaggag ttcttggcca ctggctccag aatcgccacg cactccacat
    39001 gatgcgtcat cggaaacacg tcacgtcaca agagacatgg catacctgca ggtcaggagc
    39061 caagtttcga cctgcctggt gggcctttgg gtgctttgcg cgtcaaacga gcgtcacgac
    39121 agcccagagc atcctcctca tgtggccgct tcgaagaagt accgagaggg tgtcggccgt
    39181 cacacgcctc gcggaattct ttcctgtctc ggcggctgtc gcgctgcacg taacgagctc
    39241 gtgcatgggt ggcggtagcg cgtcgaaggc ccctgactgt ccgccgtgtt cacgttcgtg
    39301 taccgctggc cgtgacggcc tgctgatgcg agagcagtcc ggcgacggct tggatggtgt
    39361 cactcttgtg ctcgcgacgg ccgtggtggc gggcaaggga tcgccagttc ttcagatggt
    39421 cgatgccgtg ctcgacccgg atgcggcgtg aggagtgggc cttgcgctga cgctcgtcca
    39481 tcccctcata tcactcgggc gggttcttct tgaacttgcg gtgcggtggc gtcaccacgc
    39541 ggcctctggt ctgggcgccc aggccttggt agccagcatc ggcgaggatc tccgcggccg
    39601 gaccgtcggc caagagcttg accaggccca gcttccgggc gtgcgtgatg tccgcaaagc
    39661 tcgcaggctc ggccggactg cagaacagcg gccgcccctc ggcgtccgtg acgaccatgg
    39721 cgacttgacg gcgctttgct tgttcttccc ggcgatcaac ttctcccggt ccttgcgtcc
    39781 gacagccggg cgacgcaccc ggacctcggt gccgccgatg attccggttt gcccgctcgc
    39841 gcccagatgg tcgatgacct cggcgagtgt gcgcagtcgg atgtcaggcg cgacggtgca
    39901 gccccgctcg gcgagcagtg gccgcacttc accgatcgca cgcgtaatgg tggagcggtc
    39961 cacgccgaac cagcaggcca gcacgtcgtg cgtcgttgca tgacggagat gcacgagcgt
    40021 ggccaacagg cggtcgacga agaccagctt gcactcggcc ccggcaccga cggccccgcg
    40081 gcgagggcgt gacgtcagca cggcctggtg ccgctcgtgc cacaacggac cgatctctgc
    40141 gacgagttct gcaatcacgt cgggcgccag cccggtgatc cgctgggtac ggatgattgc
    40201 tgcacgtgtc cggctcccca ccacacggat catgatcaac gatcaagatc tcgacgcgct
    40261 accgccaacc atgcacgagc tcgtaagggc tgtcccgtaa ctgctggcta cggatgagat
    40321 gatcatggcg cgcctgatgt gatcacggcg tcggagccgt cctggatagc cccgttcacc
    40381 gggctgagcc cgcggcagtt cgggaagctg gtggcggttc tgaggcgtga gggcgcggac
    40441 gcggtccgca agggccggcc gtggagcctt gcgctggagg accggtccct gccggtcgcg
    40501 gcctactggc gcacaaaact gaccatgcga cagctcgccc cgttgttcgg ggtgtccaag
    40561 tcggcggcgg accggatcat cgaccacctc ggaccgatgc tcgctctcca gccccgcaaa
    40621 gtagcggcta cgtttttacc cgtcccgacg gcgccccgat cgaaggatcc accctcaccc
    40681 ggcacttcaa caccctgctc cgccgtgccg ggctccgccg catccggttc cacgacctcc
    40741 gccactcgac cacgaccctc cttctcgaac aaggagtgga actcgtcgtg atcaaggaac
    40801 tgctggggca cgcccacatc ggcgtcaccg ccaccgtgta cgcccacgtc cggctccgtc
    40861 ttcagcgcga cgccatcgac ctcctcggcc acgccctccg ctaccccgca gagatcaccg
    40921 acaagcccga cagcgatgat gaaccgccct tcgccggagc cgtcgtccgc tgacgttgcc
    40981 gtcaactact gccgtcacac cgcgccgaag ccccgccagg ctgtgcctgg cggggcttca
    41041 gatttgcggt cgctcactcc gatcgggtcc gcatcagacg atcacgacgc accccaattt
    41101 gaagcggaga cgggagccca ctcgcttatc ccgtaaccag ctcacgcatt cgcgcgatta
    41161 gatcacgaga tccgaggtct gccgacagcc gaacaagtcg cccgtaatac tcctcactaa
    41221 tcgacaactc gtcctcgtaa atccatgagc acattgtgtc gaaagctagg gcgaactctc
    41281 cggccaccag aaggtcgcgc acgtcaactg cgactgaagg tgcagtgatg ggagattcct
    41341 ctagcagttc ttcgatcttg gcggcgtact ctacggcttc cactgcacct ccatcagggt
    41401 cgatacggga agccggtcac gattcggtct gttgcaggtt catagatgac cctgatgttc
    41461 acgccgtcca ctactccttc aaccttccac cgcgacggat ccccgttcct cgtatacagg
    41521 gctccagctc ggcctgtctg ctgcgtcctg acactgttcg gactggtcgc cacatcggca
    41581 atgctgtcga ggatcttgtc ggtgtcccag ccgcgtggaa acacggtctt cccaggctgt
    41641 cccggccact tatggccacc acccgttctg tcaccgtgaa tgatatggaa ctgctcttgc
    41701 ccaccgatca agtcgcgtcc ggcgccggcg caattactgt tgtgaacgag gaccggcgtc
    41761 tgcccagcga gtacatagta cgtgtggagg tcagtgatcg tcaggttgta cgtgcgcgcc
    41821 tcgtccgcat agcgtctgac cttctccact gcgaccgtgc gaccgtcgtc cgtacgcaat
    41881 cgtgtacccg gcgtcagatc ctcagcatcc acccattcct tcgcgctgac cgaccagaaa
    41941 gggtgctcgt gggtagcggt gagtcgctca gggccttccg gcgtaccgac ggtgagctcg
    42001 acaaatacct tgtcgttgtc agtgacaatg gtcgcggcga cctcttcggc gaccgtctct
    42061 cccgtgactg gatccgtcgc caggacttcg tcaccgagct ctacttcctc gatggccttg
    42121 gttgtcccgt ccgccatgag tacctgagtg cccgcaagga agcatttctt gcaggtcttc
    42181 aagatcgtca tgacatcgct atcgacgccc ttggccccct tcgcaccctt ggctataccc
    42241 ttgagcgcct tgattcttcc gataggggtt gcatcgagag caagccaggc gcaggccgaa
    42301 acgctgcccc ccacacactc gggaacgtcc atgaagggaa cgaggtcacg ccagtcgccg
    42361 ccgccttcga agagcgatgt ctctcgcatg accgagcaga atggagccgc cttatcgccc
    42421 tcccctccac ctctacacag acgcaaaatg tgttcttcga cacggccttc gtacccgtcc
    42481 ttgtacggat acatcgcggc gagttccttc tcggaaggaa tccttatctc aagtatctcg
    42541 acagcttcag ccgatccgtc cttatttccc tgatcactgg gaaaaatggc cctgaccgta
    42601 gagcctccac ccagggtgtg ataagcaacg tctctcgttc cgtcactttt gacggtctcg
    42661 tagttccacg tccatttacc ccccttcttg ttccaggttt cggtgccccc gttgcattgc
    42721 gagctgctgc cgccgcaggc gccctcggga cgcaggcccg aggggtcgct gaaggtgatg
    42781 gggctgttgt tggcgtaggt gtagccgtgg atctgctggg tgtcggtcag gtcaaggatc
    42841 ggatcgacgg agatgaaccg gccggtgtcc cggtcgtatt cgcgggcgcc aaggtgggtg
    42901 aggccggtgg tggcggtgtc atcgatgcca ccgacaaagg cacgcttccc gggccaggac
    42961 tcgggttggg ttccgcgcgg ttgaccgaag ggagtggtgc ggcgctgcgt gagttctttt
    43021 ccgtcgatgt tgacggcgag ttgtccggtc ccttggtggt cggcgattgt cacggtcgcg
    43081 ttgcggtcgt cgtcgagaac gagttggtgg ccgtcgccaa gctcgaagta gcgggttgcc
    43141 ttggccttcg tagccccctt tgccacggtg acatctgtgt ggccgaggta gagggtggtc
    43201 tcggtgggag agcgagcgat gaggcggttg ccgtcggcgt cgtagaggta ctcagtgacc
    43261 tcatcgtcct cgccttcgac gggctgcgcg acgcggacga gtttcccttc agcgtcccag
    43321 gtcagtttct gggtgtcacc gttgatcatg cgttcggtgg tgttgccgct ggcgtcgtag
    43381 gcgtacgcgg ccttggaggt gccgcccggg cccgactggg tgacctcagt gagggtgtgg
    43441 ggctgaggac cgccggcagc tggataggtg taggcgcggg tgacgtcgtc tcctgcggca
    43501 gcaccgtgac cgtggcggac ctcggtgagg cggttgcccg ccttgtcgta cgtgtaggaa
    43561 tcccagtacg gggcgatgcc gcccaccacg ttgctggtgg gcttgtcggc gcactcctgg
    43621 gtgccctgcg tccatccttc tgtcaggcgc cgcaggtgat cgtaggtgta gcactgagtg
    43681 tcgatgccgt cacgggatac gtcggtgacg gaaaggatgt tgccgatcgc gtcgtagcgg
    43741 taggtctgct cccggtcgat accgatcccg ttctcgcggg caaccgtaga ggtggccagg
    43801 cgctgggttc cccactcaaa ggcctgggtg acttgggttc gctcggctcc tggttccttc
    43861 tgaaaggtgt actggagggg cttgcccgtg agggaacggg taatggtgtt ctgtccgttg
    43921 taggcaacgg ttccgacaat gcggagcgcc tcgtcgtact ggtaagtctg cgtggtgccg
    43981 ggcagcccgc ctgccgccga gacggtggcg gatttgacga gaccggatgg gtggtacgcc
    44041 gtgccggcct ggtaggtgcc ggccagggct tcgccttccg aagcgggaat ggtgactgca
    44101 ctgcgctcgg gccggtagag ggcgtcgtac ttcgtgatct tggatacgta ggcttcgccg
    44161 tcaacgtagc gggtggagga ggccaggaaa ccctttgcgc tgctcaccgt gtcgtattcc
    44221 cactcggccc ggagggttcc tgtggggccg tcgtcgcgca gagccgtctg gcgaccgagg
    44281 tcgtcgtacg tatggtgcac tgtgcggccg cgagcatcgg tgctggtcac aacctgattg
    44341 cgatcgttgt actgctgcac ggttctgccg gcgtctggat caaccgtttg agtggcccgg
    44401 cccagttgat cgtaggtgta ggaccaagtg ttgcccatcg ggtctgtagc gctctggagg
    44461 aggccgcccg agttgtagcg gtagcggatg gagtcgtagg cgtcggcgac gctgcggccg
    44521 tgatgggtgc gtagttcgat ggtgcgccct tgggcatcgg tcagtgcagt ggtcgcggag
    44581 gcgccttccg gcggaatgac agtggtgcgg tcaccgccgt acagggtgcg ggtgagtgcg
    44641 aggaccttcc ctccgtcaac gccgcccgcc acgtgtctct gctcggtctc gcgtcccatg
    44701 ccgtcgtagg tgtgccaggt ctgagactcc acgctgagcg cgttcgcggg ggtgaacagg
    44761 tttcgactcg gtgcgctctc cgtgtagtag ggagcgaagg agcgagaggc gagtccacgc
    44821 tcgtcgtaga agatgtcagt gatgatgcga ccgccctcga cgccgggagt ctgcgtctgg
    44881 cgtgggcgca ggtgtccgtc gtagagctcg taggagtcga gcgtgccgcc tgcgttgctg
    44941 agcgacctcg tgcgcacggc ggtgggcaag ccgtcttcga tgtagtaatc gaacgaatag
    45001 ttgggcgtca cgccggtttt ccggtcggga agccagatct ttgcctcgcg gcccagagcg
    45061 tcgtactccc gcgtggtggc cctgccgttg gggtccgtga ctaccaacgg gcttccgcgc
    45121 cgggggtcga gggtggtgac cgtcttctgc gctgtggcgg cctgccccgc cttcgctgga
    45181 ggtgtggtgc tggtgacgct gctcaagcgg ccgcgggccg gggtgtagga gatcgtcgag
    45241 gtggtcgcac cggtcctggg cgtgcgcttg ggtgccgttt ccccggttac ttggacgtct
    45301 gcggagagcg gtgtggtgga cagaatgcgg ccgtaggcgt cgaaggtgga actattctcc
    45361 aagtagatcg ctttggtgcc atcatgggac ttgagtgccg ctacggccgt ggggtttccc
    45421 ttggccggcg ccgcaccgta agcctggccg tcataagcgg tgagagtgtc ggtgagcacg
    45481 tccttggccc ggtcgggggc cacgtcgcag gagacggcca ccgtttcgct gcgatagagc
    45541 gccgccagaa tgttcagctc ggcgttgggg acatactcgt gccgggtgca ctggttgtct
    45601 gcagcggttg cattgtcacc tcggttgtca atctgtagga ctcgccctga gtcagcgtca
    45661 tacgtggtcg acttggaggt aatccgccac tccttgccgg caccgtcgtc ggtggaggtc
    45721 caggtgcggg agctggcagt cccggtgaag tgggatctga tcgtgcccca gttcctcttc
    45781 ttctccgcgg tctcgtagta ccagggccgt tcgagcgtct tgcccagaac tcttccgcca
    45841 ggtccggagt agccggcgct cttgtacaaa aatccggcag ctgattcgtg gtccgttatc
    45901 ggatcgccct cgccctcacc gaggggcaag gacaccgatt tggtgccccc tgaaggttcc
    45961 ttgcggtcac cgttcatgcc gcgcatgaag taggagtcgc tctgggacct catggcggag
    46021 tcgccgccct cacctccgtc gagcacccgg acgtggccgt aaccgcgcca ctgcgaccac
    46081 gtgcggatgt cgtcctcgac catcccgtcg ctgtcgtcgt agtgccaggc tccaccgccc
    46141 aggtactcgt agcgggttac ctggtcaggg gcgccgccgg ttcggtcggt gagcgtcacg
    46201 tagtcgacaa cgtacttgtt gaaccagtgg gtgtacggct tctcgtcgcc ctggccctcg
    46261 ttgatctgcg gatagcaccg tgtggtgttc gtctgcggcg tcgggagtgc ggcactgtcg
    46321 catacgggcg cggagtagtt cacatccgcc ctgccaccgg tctcgtcttc gacggtagac
    46381 aggcgggcac ggatgaaggg cggatagccg tcacccgtct tgtccatccg gttggcaagc
    46441 tgcgtgtagg agagcgtcgt cttcgggaga gtgaccggcg tggtggcggt gtgacctgtg
    46501 cgctggatgg agtcgaccac caactggtag ttgatgtccg ccttctccca gcgatgggtg
    46561 atcttccagg agtcgacctt gtcgtagccc gagcccgcag tgttgagcac tcccgtggtg
    46621 acaccggtga ggcgtttacg tgtccagaag gtgggggcgt agcggccctt gtcgcagtcc
    46681 ttagcctcgg ggcagttcat gtcccagggt gtgtcgtacc agtgaaaggc gttcttctcg
    46741 atgtcggcac agtcgccggc gtctttctct atgcagcgct cggaactggt gaagtcgacc
    46801 ttggccatgg ccttggcgct gtagacgctg tcgtgcttca ggccgtactc gatgcggtcc
    46861 aggtgtccgc cacgcacgta gcgagtgttg tctttggcct ccaggttgcg gccgtaggag
    46921 ttcttctcct ggttgtagta gtacgcgatg gcattgccgc gtacgtcgac ggcgtagtcg
    46981 aggttccagc gccacgcctg ctggcaccat gaggcggcga aggtggactt gtggcattcc
    47041 tcgccggcgt cattgccgaa gaccggtacg gtccaggtgg ccccggtggt gtccttgccg
    47101 tcggtccagc cgggcaggcg gtggtatccg aagtagtagc ggtttccttg tgggtccgtg
    47161 atgcgccagt actcaccgtc gttgtccccg ttgcccctgt cggtggaggc gaggcgcttg
    47221 atgagtgtgc cgtcgtcctg ctgtagtttc caggtgtcct ggcccgtggg gacgagttcg
    47281 ccgcccttcc cgttgaacga gagaaaggcg ttgtcgtagg cccagcagag gtctcccggc
    47341 tcgttgccgt cagcgttctt gacaccgtcg tcggcgcaag gcttgtagcg gcgctcgatg
    47401 aatcccggtg agtagtcgaa gccatcgccg acccaggagc cctggttgtt ggtaccactg
    47461 gcgcggccgt cgatcgctcc ggacgagtag gagactccga cttttggcgc cgcgccgcct
    47521 gggacggctg gggcctcgaa gccataggcc cagttgaagt ccccggagtt caggtcggtc
    47581 gaccagcttg acgcgggcga gaggctggtc gccttgtagt caccgatcgg tccgctgtcg
    47641 tcggctaccg ctgccaggag ggtccggcca gctcgtagag gcacagacgc cgcagagagg
    47701 gtttgcttct ccgcatcgtt caccgtgtcg acgggcacgg cgccgccgca gtcggatctc
    47761 ctgtccgtct cgagagcgca ttcgggcagc gtcaccaacg tgaggcggct accgaacccc
    47821 gcgccgtacg cctcagcgaa ggaggcgtac ttgaggctga ccgatacacc gcctcccttg
    47881 gcggtacggc tgtcgtcctc gttctcgagg ctgagaagga caccttggac tccggcacgt
    47941 tccgtcgttg cgcgatcgag tacccgcgcc cgaaccgtgc tgggtgtctg cgccttcttc
    48001 tcggcggcac cgagcttcag cggcagcccc ttcgcctgga cgtcgggctg cccggcggag
    48061 tcggccgacg ccagcaccac gtcggtcgca ccggccttgg gccacgctgc atcgggcttg
    48121 cctgtcggga ccggcgaggg ccgcttgttc cgcggggtgc ctttgccggc tggcgcgccc
    48181 tcggtggggc gctccgagga agggactcct ggcagcggat tgtccgccac cgcaggagct
    48241 gcgacggcag agacctggag caaggtggca accatggtca gcgccgcgcc cagcgcgatc
    48301 cgtctcgtcc gggcgcggcg gaatccgcgt cggctggtca catgcacgtc aggtcagccc
    48361 ttctggccca tgcgcccggt gacgaacgca ggtcggttga tgcggtgtgc gaaaccggag
    48421 gtccccggga tggggaaccg acgggaggct cggtcagcgc aaggtgtact tcagccttgg
    48481 gggacctcgg tcggtacgtc gaaccagctt ccggccaact gctcgacctg tcgctcgctg
    48541 agggagctct ggaataccca gaggtcgtca atcacgcccg ggaagtactg gtcggtgccg
    48601 ctggcggaag ggcggccaac gctgaggctc ttagcctcga aggtcagcgc attctctgcc
    48661 caagggacgg tctccgtgca ggtgctgtcg tcagcggagc cgtctccgtc gtcgtcctga
    48721 caaacggtct cgtcgagaag cccgtcgacg tacaggcgta ccgacctgtt gaatccgtcg
    48781 taggcgactg tgatgtgggt ccattcgcgg gcatccgaga agttgccgtg agtggcagac
    48841 acgtgtgccg cttcggcgtc gtccgtttct gtaacagtca gttcccaacg gccagggccg
    48901 acgtcggcgc ccctgctgtc aggcaggaaa cgcacgccga aggcgctggt ctttgtccct
    48961 tccaattgga agaggctgag cggcttgtca gtgagtgcgg aagccttgac ccaggtagcc
    49021 acggtgaagc ttgccgaact gtcgacggga gcgtggttcg tgacggcatg tgcggtagca
    49081 ccgttgagga cgatggcgcc ctcgtcgatg tagaagtcgt cgctagtgat cgctgcgtca
    49141 cccccgagcg tcagcgcgtt gccagacccg gtgtcgtccg gagtcgtgac cggcgcggtc
    49201 ccgctcgtct cctcgaactt ccatcgtgcc ttgacgacgg ggcgctgctt gaagacctgc
    49261 tggacctcct cggcggaaac cggacggtcg aacaggcgaa cgtcgtcgat ggagccgggg
    49321 aagtggttgc ctacagcact gccgtactgt cccgcgccga tgaacatcga ctggtcggcg
    49381 tagaaggcac cgtcgagggg ggtagtgccc gccttcactc cgtttacgta gagcgtcagg
    49441 gtgccgacga ccacatcatg gacgcccgcg agatggaccc aggtgtcgga cgccgccttc
    49501 tggttgtcgg gctgcatggc ccgaatgacc ttggcatcgg ccgagtcggc cgagtattgg
    49561 ttgaaggccc aacggtcgta ggtctgggag tagtacagct cgaaaccggg acgctcgcgg
    49621 ccggcttggg ctgcgatgat cgcggccttg ctcggtttcg tcttgtccat cttggcccag
    49681 gccatcaccg cgaagctgcg ggaggtgttc acgtggggac cgctgatctt tccgaccttg
    49741 ccgtaggcgt ctgtcccgtt gaaccgggcg gccttgcccg ccacgccttc ggcaccagtg
    49801 gtgactccgc cgtggtagtc ggccggcagg acaccgccgt ggccgcgcag gcccttcgcc
    49861 gtcgccaccg agtccgccgt gtcttccatc tcaaagacgg ccgtcgcggg gcgaccgggg
    49921 tcaccgacac gctcgtgacg tgcgagcttg gccacctcgt tagctgtgat ccgcttgtcg
    49981 aagatctgaa cctcgtcgat cgcgccggga aggaagttgc ccaccttgcc gttgtgcgaa
    50041 gccgctccca gcacgaggcc tcggcgggca ttccaggcgg acggcaggtc agcctgcccg
    50101 acctgctgcc cgtcgacgta cagctcgatg aagcgctccg acccgttgta cgagccgacc
    50161 aggtgctgcc actcccctac cttcacgccg ccggcctgcg gggccatcgc gcgg
//
