LOCUS       NZ_VOGX01000018        26559 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77 scaffold11_cov50_1_2691061,
            whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000018
VERSION     NZ_VOGX01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   3  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
REFERENCE   4  (bases 1 to 2691061)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 592120
            Orig. end                         :: 618679
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000018.1.
            Bacteria and source DNA available from MEB Lab.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26559
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26559
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26559
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16559](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16559)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    21..35
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.68"
                     /tool="antismash"
     misc_feature    344..359
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.44"
                     /tool="antismash"
     misc_feature    complement(345..358)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.96"
                     /tool="antismash"
     misc_feature    complement(353..368)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.25"
                     /tool="antismash"
     misc_feature    1094..1109
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    complement(1253..1268)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            1307..1900
                     /locus_tag="FRZ02_RS04955"
                     /old_locus_tag="FRZ02_04955"
     CDS             1307..1900
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640608.1"
                     /locus_tag="FRZ02_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04955"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_146580125.1"
                     /transl_table=11
                     /translation="MAEVVLFHHAQGLTPGVVAFADGLRAAGHTVHTPDLFEGRLFGSL
                     EEGGAHVEGIGFGEITERGVRAAGQLPGDVFYAGFSLGVLPAQKLAQTRPDARGAFLVD
                     ACVPVTEFGTAWPQGVPVQVHGLEADPFFAEDRDAADRLVAESADAELFLYPGDRHLFA
                     DSSLPAHDPAAAALLNERALAFLAAHGESGLRSR"
     gene            complement(1887..2243)
                     /locus_tag="FRZ02_RS04960"
                     /old_locus_tag="FRZ02_04960"
     CDS             complement(1887..2243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414656.1"
                     /locus_tag="FRZ02_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04960"
                     /product="DUF4190 domain-containing protein"
                     /protein_id="WP_033237777.1"
                     /transl_table=11
                     /translation="MSVTQSAPGSATAERDNRAARVSAYAVVLAAFVGGGGYVPAALFL
                     PLTLTWTAVILLCGITAIVAGHVARFRAKRLGLRGRWLALAGIVGGWICVLVAVLALAA
                     VVGVIGGLAVLIDS"
     gene            2432..2656
                     /locus_tag="FRZ02_RS33335"
     CDS             2432..2656
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FRZ02_RS33335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_237534870.1"
                     /transl_table=11
                     /translation="MTGSVSVDEAMSDAELRRLLWRGTRELRPADITYRAAPLKGTGTV
                     AGQSVVHLDLPRLAVLARALREDRAGLPR"
     gene            complement(2660..3889)
                     /locus_tag="FRZ02_RS04970"
                     /old_locus_tag="FRZ02_04970"
     CDS             complement(2660..3889)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414654.1"
                     /locus_tag="FRZ02_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04970"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_010640614.1"
                     /transl_table=11
                     /translation="MTGIRTPNPLVRALRPASFGGDPAGERRRRILSSPNFADGSFRNP
                     DGVPATPSAATPRDLVRAYLSKEGRARRAPAAPIPLHPTTVADLARRPDEGLRLTWMGH
                     SSVLVEIDGARLLFDPVWGERCSPFGFAGPRRLHPAPVPLRALEAVDAVVISHDHYDHL
                     DMPTIRALVRTGTVFVVPLGVGAHLERWGVPAGRLRELDWREATQVAGVTLTATPARHF
                     CGRGLRNQQHTLWASWSVRGSDHRVFHSGDTGYFPGFRDIGAEHGPFDATMIQIGAYSE
                     FLPHSRGGATRDPGPWPDIHMTPDEGLRAHLDLQGGAPHGVLLPIHWGTFNLALHPWEE
                     PAERTLLAAHRAGQQVITPLPGEPVIPAHAPAADPWWRAVAATTPGEGWAAWPPAGEQL
                     DALDLAAPER"
     misc_feature    3991..4000
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(4037..4825)
                     /locus_tag="FRZ02_RS04975"
                     /old_locus_tag="FRZ02_04975"
     CDS             complement(4037..4825)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642841.1"
                     /locus_tag="FRZ02_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04975"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_030307672.1"
                     /transl_table=11
                     /translation="MTAETTSPAPDFTSYAAVGDSFTEGVGDPGPDGAFVGWADRLAVL
                     LADRQPEHAFRYANLAVRGKLLDQIVADQVPRARELSPDLVTFCAGGNDVIRPGTDPDD
                     LAERFEKAVTALTSDVGTVVLTTGFDTRGVPVLKHLRGKVATYNGHVRAIADRYGCPVL
                     DLWSLRSVQDRRAWDADRLHLSAEGHTRVALRAGQILGVEVPADPDEEWPTLPPRTPLD
                     GRRDDIQWAREYLVPWIGRRLRGVSSGDHVSAKRPDLLPL"
     gene            5115..5930
                     /locus_tag="FRZ02_RS04980"
                     /old_locus_tag="FRZ02_04980"
     CDS             5115..5930
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642844.1"
                     /locus_tag="FRZ02_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04980"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_003952093.1"
                     /transl_table=11
                     /translation="MTQQSPSTRSESMPEPELTGVRNFRDVGGLPTADGRRVRAGQLFR
                     SGHLAHATEADTGFLSGLGLHTVFDFRNSADRALDGLDVELPGVRNVNIPLSDPADGAG
                     FWKMVREGDLPQLRSLLGDGKAALRMTTSYREMITGRTTEHSRVLRSLAEESVPALMHC
                     AAGKDRAGLSVAVTLLALGVDREAIEADYLESNAQHRRYRIRRASDSPDALSPEVMELL
                     SPLFEARAEYLAAAFETIDATWGGTERYLTDGLRLTPELRDRLHGRLLD"
     gene            complement(5940..6125)
                     /locus_tag="FRZ02_RS04985"
                     /old_locus_tag="FRZ02_04985"
     CDS             complement(5940..6125)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640621.1"
                     /locus_tag="FRZ02_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04985"
                     /product="DUF6126 family protein"
                     /protein_id="WP_010640621.1"
                     /transl_table=11
                     /translation="MSERPETEPGAPAEQAPARAGRDMEERLPPSLWIRLLIYVVVGHL
                     LAGFIYLLFEVGSKAQ"
     gene            complement(6122..6739)
                     /locus_tag="FRZ02_RS04990"
                     /old_locus_tag="FRZ02_04990"
     CDS             complement(6122..6739)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893332.1"
                     /locus_tag="FRZ02_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04990"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_018893332.1"
                     /transl_table=11
                     /translation="MTTDRPDDPAALPAVAPQLRELRRRAGHTLETAARAAGLSAAHLS
                     RLETGQRQPSLPMLLALARVYGTTVSALLGETGGEQHAVIRGAEAEPAPAGGWTYWPAG
                     GSGRAMQALRVRVPYGAQGDMVRVHPGEEWLHVLRGRLRLRLGESEHLLHPGDGAHFDS
                     LTPHRIGAADADGAELLFVHTLLQSPGAPCLGPGHPNPKGPA"
     misc_feature    6747..6760
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            complement(6807..8231)
                     /locus_tag="FRZ02_RS04995"
                     /old_locus_tag="FRZ02_04995"
     CDS             complement(6807..8231)
                     /NRPS_PKS="Domain: Aminotran_3 (55-377). E-value: 5.5e-87.
                     Score: 283.9. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS04995_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893331.1"
                     /locus_tag="FRZ02_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_04995"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_010640625.1"
                     /sec_met_domain="Aminotran_3 (E-value: 6.3e-84, bitscore:
                     279.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVDGGTPATGAGPAPGFDLRRLLAERGGERYALHARHLNPQLP
                     RMLRTLGFDKVYERAEGAHFWDAEGNDHLDMLAGFGVMGLGRHHPVIRQALHDVLDLSL
                     PDLTRFDCPPLPGLLAERLLAYTPHLHRAFFCSSGTEAVETALKFARRATGRPRVLHCA
                     HSFHGLTTGALSVNGERSFRDGFGPLLPDTAVPLGDLDALRRELRAGDVAGLIVEPVQG
                     KGVHAAPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFHAHQHEDGVEPDLVCLAKA
                     LSGGYVPVGATLGTDEVFAKVYSSMDRVLVHSASFGANAQAMAAGLAVLDVMEREDTVA
                     HVRRVGERLRSRLAALVPRYELLHEVRGRGLMIGIEFGRPESLRLRSRWAMLQAARKGL
                     FAQMVVAPLLHRHRILTQVSGDHLEVIKLIPPLVVDEADVDRFVDAFTQVMDEAQDGGL
                     LWEFGRTLVRQAVVHR"
     aSDomain        complement(7101..8066)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS04995_Aminotran_3.1"
                     /evalue="5.50E-87"
                     /label="FRZ02_RS04995_Aminotran_3.1"
                     /locus_tag="FRZ02_RS04995"
                     /protein_end="377"
                     /protein_start="55"
                     /score="283.9"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDAEGNDHLDMLAGFGVMGLGRHHPVIRQALHDVL
                     DLSLPDLTRFDCPPLPGLLAERLLAYTPHLHRAFFCSSGTEAVETALKFARRATGRPRV
                     LHCAHSFHGLTTGALSVNGERSFRDGFGPLLPDTAVPLGDLDALRRELRAGDVAGLIVE
                     PVQGKGVHAAPPGYLRAAQELLHRHKALLIADEVQTGLGRTGDFHAHQHEDGVEPDLVC
                     LAKALSGGYVPVGATLGTDEVFAKVYSSMDRVLVHSASFGANAQAMAAGLAVLDVMERE
                     DTVAHVRRVGERLRSRLAALVPRYELLHEVRGRGLMIGIEF"
     gene            complement(8302..9324)
                     /gene="hpnH"
                     /locus_tag="FRZ02_RS05000"
                     /old_locus_tag="FRZ02_05000"
     CDS             complement(8302..9324)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952089.1"
                     /locus_tag="FRZ02_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05000"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_008406041.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-16, bitscore: 58.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.9e-09, bitscore: 33.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIKVATYLAEQKLRRREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVNQLVAKRKYVF
                     LCTNAMLMRKKMDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVAAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKTFADGNRRRWRLNHSPLFLDFLEGKADFACTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETVTSNRA
                     "
     gene            complement(9330..10001)
                     /locus_tag="FRZ02_RS05005"
                     /old_locus_tag="FRZ02_05005"
     CDS             complement(9330..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893330.1"
                     /locus_tag="FRZ02_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05005"
                     /product="lipoprotein"
                     /protein_id="WP_015506752.1"
                     /transl_table=11
                     /translation="MTRPAAAGPLPGPAAGPAPLVIACALTIERLALRTGTRAPADTPT
                     RVLRTGMGPEAAGRAVAEALRDPALARAGVVATGFCAGLGAGMHPGDLVVADEVRDPRG
                     VTRCAEAGVLAAAVARAVPGRTVHTGPLTGCDHVVRGAERARLRSQGAVAVDMESAATL
                     YTARLAGPRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVIPAFYEWHRSSLLPR
                     R"
     gene            complement(10001..11992)
                     /gene="shc"
                     /locus_tag="FRZ02_RS05010"
                     /old_locus_tag="FRZ02_05010"
     CDS             complement(10001..11992)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640630.1"
                     /locus_tag="FRZ02_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05010"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_030766491.1"
                     /sec_met_domain="T2TS (E-value: 2.8e-150, bitscore: 498.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTNGPAGAAPSRPAPARTTAATTDTAALDGAAVEAAAERARA
                     RAADHLLGLQSPEGWWKGDLDTNVTMDAEDLLLRQFLGIRDEATTRSAALFIRGEQRED
                     GTWATFHGGPPDLSTTVEAYVALRLAGDSPDAPHMTRAAHWVRSQGGIAEARVFTRIWL
                     ALFGWWPWDRLPELPPELIFLPPWAPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFPL
                     DELHTDPADPAPRARFAPLASWNGAFQRLDRALHAYRKVAPRALRRAAMATAGRWIVER
                     QENDGCWGGIQPPAVYSMIALHLLGYDLGHPVMRAGLESLDRFTLTREDGSRMVEACQS
                     PVWDTCLATIALADAGVPADHPQLVRAADWMLDEQIERPGDWSVRRPNLAPGGWAFEFH
                     NDNYPDIDDTAEVVLALRRVRHPDTARMERAISLGVRWNLGMQSKNGAWGAFDVDNTSS
                     LPNRLPFCDFGEVVDPPSADVTAHVVEMLAAEGLAADPRTRRAVDWLLAEQEPSGAWFG
                     RWGVNYLYGTGSAVPALVDAGLPTTHPAIRRAVAWLESVQNDDGGWGEDLRSYREQGRM
                     ARGASTASQTGWALMALLAAGERESRAARRGVTFLAETQHEDGSWEEPYYTGTGFPWDF
                     SINYHLYRQVFPLTALGRYTRGAAPEGA"
     gene            complement(12188..13255)
                     /locus_tag="FRZ02_RS05015"
                     /old_locus_tag="FRZ02_05015"
     CDS             complement(12188..13255)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006377568.1"
                     /locus_tag="FRZ02_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05015"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_026048190.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-58, bitscore:
                     195.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTVPTADADRDTTDVAALLERGRTLATPVLKAAIERLAPPMDTV
                     AAYHFGWIDAAGHPAEGDGGKAVRPALALLSAEAAGAAPEAGIPGAVAVELVHNFSLLH
                     DDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEILLELGTLEAGRAARRLTTAS
                     RALIDGQAQDISYEHRERVSVEECLEMEGNKTGALLACAVSIGAVLGGADDRTADALER
                     YGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAEGPAAERLGSL
                     LAADAKANDFENFSEDEFAARAALIEEAGGRAWTEAEARRQHTVAIEALSGVGMPDHVR
                     EQLTALADFVVVRKR"
     gene            complement(13328..14704)
                     /gene="hpnE"
                     /locus_tag="FRZ02_RS05020"
                     /old_locus_tag="FRZ02_05020"
     CDS             complement(13328..14704)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015506754.1"
                     /locus_tag="FRZ02_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05020"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_010640635.1"
                     /transl_table=11
                     /translation="MTTAAAREAVVVGGGLAGTAAALALADAGVRVTLLEGRPRLGGLA
                     FSFQRGGLTVDNGQHVYLRCCTAYRWFLDRVDGAALAPVQDRLDVPVLDAGRGRLGRLR
                     RNALPVPFHLGPSLARYPHLSLAEKAAVGRAALALRRLDPADPALDRQDFGSWLRRHGQ
                     SPRAVAALWDLVGVATLNAAADDASLALAAKVFRTGLLSDAGAADIGWAHVPLGELHHT
                     RALTSLDKAGVRTVLRARVRGVTPGGEGARWQVETGDETLTADTVVLAVPPAETHELLP
                     GGALDEPEKLTRIGTAPIINIHVLYDRKVVRRPFFTALDGPVQWVFDRTEASGLDHGQY
                     LALSQSTAQAEIDTPVADLRARYLPELERLLPAARTARVEDFFVTRERTATFAAVPGVG
                     ALRPGPATRLPGLHLAGAWTATGWPATMEGAVRSGLNAASDALGALGRPRPAPVFDEAA
                     "
     gene            complement(14701..15651)
                     /gene="hpnD"
                     /locus_tag="FRZ02_RS05025"
                     /old_locus_tag="FRZ02_05025"
     CDS             complement(14701..15651)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893328.1"
                     /locus_tag="FRZ02_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05025"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_018468910.1"
                     /sec_met_domain="phytoene_synt (E-value: 2e-55, bitscore:
                     185.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.3e-68,
                     bitscore: 227.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPTVEDSISLPAPVLAAYSYCETVTGSEARNFAYGIRLLPVAER
                     RAMSALYAFSRRVDDIGDGTLAPEVKADRLGATRDILDRIRDGKVDEDDTDPVAVALAD
                     AARRFPIPLGGLDELIDGVLMDVKGVTYETWDDLKLYCRCVAGAIGRLSLGIFGPAPGA
                     PQTEKAAEYADTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSDGFDGPHPPAG
                     SDFPGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPLAVLR
                     GRVSLPGHEKAYVAVRGLSGFDARQIGRQAGRRRA"
     gene            complement(15648..16559)
                     /gene="hpnC"
                     /locus_tag="FRZ02_RS05030"
                     /old_locus_tag="FRZ02_05030"
     CDS             complement(15648..16559)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018468911.1"
                     /locus_tag="FRZ02_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05030"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_121842439.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-37, bitscore:
                     125.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.7e-38,
                     bitscore: 128.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPGRAQHGAPVRATLDKAAAENFPVAPFFVPRAWRRGLMAVYG
                     YARLVDDIGDGDLTPGGADARLLGVEGSAAEDRLTLLDALEADLARVFATTGPGPAHPL
                     VAALRPVVRAHGLTPEPFRALIQANRQDQLVTRYETWDDLAAYCELSANPVGHLVLGLT
                     GTLTPERVRRSDAVCTGLQIVEHLQDVAEDLARDRIYLPAEDLKRFRVEESDLAAPTAS
                     ASLRALVAYEASRAGELLAEGGPLIASVHGRLRLLLAGFVGGGRAALAAVTDAGYDVLP
                     GPPRPTKPRLLREVGAALRGER"
     gene            complement(16972..17769)
                     /locus_tag="FRZ02_RS05035"
                     /old_locus_tag="FRZ02_05035"
     CDS             complement(16972..17769)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413844.1"
                     /locus_tag="FRZ02_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05035"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_008413844.1"
                     /transl_table=11
                     /translation="MAEADVDQGAPGGPRTPTVIADDLHIVYRVNGTKGGKGSATAALS
                     RILKRGEERGVRKVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLKAVAGLLPAESGKVY
                     TDGQPSLLGVNAALMNDLTGERNVMLGGLAMGMTREQIRERYQGIVDFSGINEKGDFIT
                     LPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDKKFQKRSEARIRELRKEAGTVF
                     LVSHNNKSIRDTCDRVIWLEHGELRLDGPTAEVLKEYEKFTSK"
     gene            complement(17756..18697)
                     /locus_tag="FRZ02_RS05040"
                     /old_locus_tag="FRZ02_05040"
     CDS             complement(17756..18697)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133319.1"
                     /locus_tag="FRZ02_RS05040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05040"
                     /product="ABC transporter permease"
                     /protein_id="WP_103487138.1"
                     /transl_table=11
                     /translation="MSETTQDGGVAVSAAPPSPDDGLSPAQLAEKYGLSVSGARPGLLA
                     YVKQLWGRRHFIVAFSQAKLTAQYSQAKLGQLWQVVTPLLNAAVYFFIFGVLLDAKRGI
                     PEHVYVPFLVTGVFVFTFTQSSVMSGVRSISGNLGLVRALHFPRASLPISFSLQQLQQL
                     LFSMIVLVAIVMGFGSYPTWSWLLVLPALALQFVFNTGLALIFARLGSKTPDLAQLMPF
                     VMRTWMYASGVMFSIPVMLARNDRLPHWLSDVLQWNPAAVYMDLVRFALIDDYTAKYLP
                     AHVWAIALGWALVAGVAGFVYFWKSEERYGRG"
     gene            complement(18815..19660)
                     /locus_tag="FRZ02_RS05045"
                     /old_locus_tag="FRZ02_05045"
     CDS             complement(18815..19660)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007819843.1"
                     /locus_tag="FRZ02_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05045"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_129861899.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.9e-09,
                     bitscore: 33.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGNRPEELRALIDSVAKQDGDPVQIAVVGNGSPVPEVPEGVRTTE
                     LPENLGIPGGRNVGIEMFGPAGREVDILLFLDDDGLLARTDTAELCREAFTADPELGIV
                     SFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVFAEAGLLPADFFYA
                     HEETDLAWRALNAGWQIDYRSDMVLYHPTTAPSRHAVYHRMVARNRVWLARRNLPLPLV
                     PVYLGVWLLLTLLRRPSGAALKAWFGGFKEGWTSSAGPRRPMKWRTVWRLTRLGRPPVI
                     "
     gene            complement(19708..20487)
                     /locus_tag="FRZ02_RS05050"
                     /old_locus_tag="FRZ02_05050"
     CDS             complement(19708..20487)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="FRZ02_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05050"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_008413838.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREISLRVDRYVV
                     PTRITPNQLTYLMTVFGVLACPALLVPGIWGALLGALMVQLYLLLDCVDGEVARWKKQF
                     SLGGVYLDRVGAYLCDAAVLVGLGLRGADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKEAASEPRSSKVAFARKAAAALKFHRLVLGIEASLLIIVLAVADQ
                     IRGDLFFTRLGIAVLAGIALLQTLLHLVSILVSSRLR"
     gene            complement(20465..21526)
                     /locus_tag="FRZ02_RS05055"
                     /old_locus_tag="FRZ02_05055"
     CDS             complement(20465..21526)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="FRZ02_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05055"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_008413836.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.4e-22, bitscore: 77.1,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPLVVDIRRGALNDLASVLADQRISSSGKLAIAISG
                     GSGARLRERLSPALPGASWYEVGGGTLDDAVKLADAMKSGRYDAVVGLGGGKIIDCAKF
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIGVVIDLDIIREAPARF
                     VRSGIGDALSNISAVADWELSARVRGEDIDGLAAAMARQAGEAVLRHPGDVGDDGFLQV
                     LAEGLVLTGISMSVAGDSRPASGACHEINHAFDLLFPKRAASHGEQCGMGAAFAMHLRG
                     APAESAQMAEVLRRHGLPVVPADIGFTVDEFVQVVEFAPQTRPGRYTILEHLNLSTDQI
                     KDAYADYAKAIGS"
     gene            complement(21514..22266)
                     /locus_tag="FRZ02_RS05060"
                     /old_locus_tag="FRZ02_05060"
     CDS             complement(21514..22266)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="FRZ02_RS05060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05060"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_003952078.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-10, bitscore:
                     38.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGDEESLTVLDLTLG
                     NFAEIGLEEVGVIVGYRKEAVYERKAALEAKYGLKITLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGNGQKIILALDTVKNLADEEMKVVVDPDKGVQR
                     ITKLMDPAEATGEYIGVTLIEGEAAEELADALRTTFERDPQLYYEDGYQELVNRGFKID
                     VAPIGEVSWVEIDNHEDLAKGREIACRY"
     gene            complement(22263..24062)
                     /locus_tag="FRZ02_RS05065"
                     /old_locus_tag="FRZ02_05065"
     CDS             complement(22263..24062)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="FRZ02_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05065"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_146580129.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSPIEGELRTLGFDVRTASDAAEAAALLRTVPT
                     GRVALVDAGFVGHLHALRLGLTDPRFPAGTVPGAVTVQDASRAALTRALEAEAGRPAPG
                     GAAVRTGTGLPDRLAGALQAEGVAVHRPELGALVARVPLAPQERSEARQAVAAVDDEAI
                     RLRTAVKSRDGFFTTYCISPYSRYLARWCARRGLTPNQVTTASLVTALIAAGCAATGTR
                     AGFVAAGLLLLFSFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAAR
                     GGDDVWALALGAMVLQTCRHVVDFSFNEANHDAEANTSPTAALSGRLDSVGWTVWLRRM
                     IVLPIGERWALIAVLTAVTTPRITFVVLLIGCALAAAYTTAGRLLRSLTRKAERTDRAA
                     QALADLADSGPLAEALSPRLRPFAKLPAPAVAALGGVILVAVTALTPAGSAGPLLGAVV
                     YVLCSALAVSRPLTGALDWLVPPFFRAAEYGVILLLAARADDSGALPAAFGLVAAVAYH
                     HYDTVYRIRGGSGAPPRALVRATGGHEGRVLLVTAASLLAPSGFTVALTVLAVAVALVV
                     LAESIRFWVSAGAPAVHDEGEPA"
     misc_feature    complement(24508..24522)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.39"
                     /tool="antismash"
     gene            24614..25552
                     /locus_tag="FRZ02_RS05070"
                     /old_locus_tag="FRZ02_05070"
     CDS             24614..25552
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="FRZ02_RS05070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05070"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_018468914.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGPATGTAASAHRGRLRIALGITLFVMVAEIVGGL
                     LADSLALVADAAHMATDALGLGMALLAIHFANRPPSEKRTFGFARAEILAALANCLLLL
                     GVGGYVVYEAVERFFFTPAETSGPLALAFGAVGLLANVVSLSLLMRGQRESLNVRGAFL
                     EVAADALGSVAVILSALVIMATGWQAADPIASLLIGAMIVPRTLRLLRETLDILLEAAP
                     KGVDMAEVRRHMEELPGVVGVHDLHAWTITSGMPVLSAHVVVEADQLDAAAHEKLLHEL
                     QECLGGHFDVEHCTFQLEPSGHAPHEAGLCH"
     misc_feature    25576..25591
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    complement(25812..25828)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     gene            25867..26463
                     /gene="idi"
                     /locus_tag="FRZ02_RS05075"
                     /old_locus_tag="FRZ02_05075"
     CDS             25867..26463
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129457.1"
                     /locus_tag="FRZ02_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_05075"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_003952075.1"
                     /transl_table=11
                     /translation="MPITPATAVSRSSDDSPEAVILLELVDEDGNTIGTAEKLSAHQAP
                     GRLHRAFSVFLFDERGRLLLQQRALGKYHSPGVWSNTCCGHPYPGEAPFAAAARRTFEE
                     LGVSPALLGEAGTVRYNHPDPASGLVEQEYNHLFVGLVRDPLRPDPEEVGDTVFVTPAE
                     LAERHEAGPFSAWFMTVLDAARPAIRELTGDSTGW"
ORIGIN
        1 gaccagttcg gcgaggaggt ggatggtgtc ggcgacggcg tggccgcgta cgtccccgtc
       61 gatcgggggc accagcttga cccgcgagta ctgctcgacc tcggcgatgg cggagcgcag
      121 cacctcggtc atggagaccg gcctgctcca ctggcggcgg gacatcgcgc cgccgaggac
      181 ggcgaggttc tcggcgtggc ggcggatgcg ggtggagagg tggtcgacgt ggaagaggcc
      241 cttgagcagg tcggggtcct cgacctggtt ctccagttcg tccaggagct ggatctcgcg
      301 gtggacgagg gactgcaggc gccgggcgag gttgacgaag acctcgacct tctgttcgct
      361 gccggcctgg ctggagagct gggcggcctg gaccacggcg tggacggcca tccggtgggc
      421 gcggtggagt tcctcgccga gcaggtcgaa gccgtcgccg cgcggggcga ggggcggctg
      481 ctgggcggtg ggctgctcgc cccggcggag ggcgtcgagg acgtcgcgca gttcggcctg
      541 gttgcgggcg ctggtgcggc ggagctgcgc ggcgcggtcc aggatgttcc gcgcggtgcg
      601 gtcggcggcg acggcggcga cggcgatccc ggtgagggcc acggcggcgg cgccggcgag
      661 gatcgcccag agcagcgggg aggcggtttc gccgccgtcg gcggaacgca gcgcgaagag
      721 caccgcggcg gcgccgccga gggagaccgc gacggccggc aggaccgcga tccgcagcag
      781 ctgaggccgt atgtgcgcct cggggagctg ctgggcggcc ttgccgtgcc ggccgccgcc
      841 ctcacggcgg tccgcccggt tggcggccgg tgcgcgtagt tgtgacatcg acgtcctcgg
      901 aagaaacccc ccggtccggc gtggggcggg ggtgcggtag cggggctcct ggtggggcgc
      961 ggcccggaag cgcgcgatgc gtggcgggca tgcgacgccg gtccgcgagg gcaacggaga
     1021 gaccctggcg tgggctccgc gcgacctgac gagcacacac ggtagtcatc aaagcatccc
     1081 gtgcggtggg cagttgacca cttggaccgg cagcacccca cccccggacg acagctcgca
     1141 caccagcccg aaatccgaag ggggacaagg gttcgaaggt cgatggaggc cactcggcga
     1201 ggcggcgcgc gaggtcgtac gacggacacg gtcacccctt gggggctacc ctccgcacat
     1261 gcgtccgacg ggggcgccgg atgagcgaga ggcaagggcc gcggacatgg ctgaggtcgt
     1321 cctgttccac cacgcgcagg ggctgactcc cggcgtcgtc gcgttcgccg acggtctccg
     1381 ggcggcgggt cacacggtcc acaccccgga cctcttcgaa gggcgcctct tcgggtcgct
     1441 ggaggagggc ggcgcccacg tcgagggcat cggcttcggc gagatcaccg agcgcggcgt
     1501 gcgcgcggcc gggcagctgc ccggtgacgt cttctacgcc ggcttctccc tcggcgtgct
     1561 ccccgcccag aagctggcgc agacccggcc ggacgcgcgg ggcgcgttcc tggtcgacgc
     1621 ctgcgtcccc gtcacggagt tcggcaccgc ctggccgcag ggcgtaccgg tgcaggtcca
     1681 cgggctggag gccgatccgt tcttcgccga ggaccgcgac gccgccgacc ggctcgtcgc
     1741 ggagtcggcc gacgcggagc tgttcctgta ccccggggac cggcacctct tcgcggactc
     1801 gtccctgcct gcccacgacc cggcggccgc cgctctgctg aacgagcggg cgctcgcctt
     1861 cctcgccgcg cacggcgaga gcggcctcag gagtcgatga gtacggccag tccgccgatc
     1921 acgccgacca cggccgcgag cgccagcacg gccaccagga cgcagatcca gccgccgacg
     1981 atcccggcga gggcgagcca acgaccgcgc aggccaaggc gtttggcgcg gaagcgggcg
     2041 acgtggcccg cgacgatcgc ggtgatcccg caaaggagga tcacggccgt ccacgtgagc
     2101 gtcagcggga ggaagagcgc ggcgggcacg tagccgccgc ctccgacgaa cgccgcgagg
     2161 acgacggcgt aggcactgac ccgggcggca cggttgtccc gttccgccgt cgcggagccc
     2221 ggagctgact gggtgacgga catggcgggg accttagcaa gaggcccagg cgccggacct
     2281 ggcgcgtcct gccggggaga ggtcagcccc ggccgcccag cacccgcgcc acctgggcgg
     2341 cgagggcgtc gaggaggcgt tccgcgaggg gcgagccggg ctccgcgccg gggccggcgg
     2401 tccgctcggg ctcaagggcg tccttgacgc ggtgaccggc agcgtgagcg tggacgaggc
     2461 gatgagcgac gcggagctgc gccgcctgct gtggcggggc acccgggaac tgcgccccgc
     2521 cgacatcacc taccgcgcgg ccccgctcaa gggcaccggt acggtcgccg ggcagtccgt
     2581 ggtccacctc gacctgcccc ggctcgccgt actggcccgg gccctgcgcg aggaccgagc
     2641 cggcctgccg cggtgaggct cagcgctcgg gggccgccag gtccagcgcg tcgagctgct
     2701 ccccggccgg cggccaggcg gcccagccct ccccgggggt cgtcgccgcg accgcgcgcc
     2761 accaggggtc ggcggcgggc gcgtgcgccg ggatcaccgg ctcgccgggg agcggggtga
     2821 tgacctgctg gcccgcgcgg tgggcggcga gcagggtgcg ctcggccggt tcctcccagg
     2881 ggtgcagggc caggttgaag gtgccccagt ggatcgggag caggacgccg tgcggcgcgc
     2941 cgccctggag gtcgaggtgg gcgcgcagcc cctcgtcggg cgtcatgtgg atgtcgggcc
     3001 agggccccgg gtcgcgggtc gccccgcccc ggctgtgcgg caggaactcg ctgtacgcgc
     3061 cgatctggat catcgtcgcg tcgaagggac cgtgctcggc gccgatgtcc cggaagccgg
     3121 ggaagtaccc ggtgtcgccg ctgtggaaga cccggtggtc gctgccccgg accgaccagg
     3181 aggcccagag cgtgtgctgc tggttgcgca ggccccgccc gcagaagtgg cgggccgggg
     3241 tggcggtcag ggtgaccccg gcgacctggg tggcctcgcg ccagtccagc tcgcgcagcc
     3301 gcccggcggg gacgccccac cgctccaggt gggcgccgac ccccagcggg accacgaaga
     3361 cggtgccggt gcggaccagg gcccggatgg tcggcatgtc caggtggtcg tagtggtcgt
     3421 gggagatgac cacggcgtcg accgcctcca gggcgcgcag cggcaccggc gccgggtgga
     3481 ggcggcgcgg cccggcgaag ccgaacgggg agcaccgctc accccagacg gggtcgaaga
     3541 gcaggcgcgc cccgtcgatc tcgacgagga cgctggagtg gcccatccag gtgagccgca
     3601 gcccctcgtc gggccgccgg gcgaggtcgg ccacggtggt ggggtggagc gggatcgggg
     3661 ccgccggggc acgccgggcc cggccctcct tgctcaggta ggcgcggacc aggtcgcgcg
     3721 gggtcgcggc ggagggggtg gccgggacgc cgtcggggtt gcggaacgag ccgtccgcga
     3781 agttcggcga actgaggatg cgccgccggc gctctcccgc gggatcaccg ccgaacgagg
     3841 ccggccgcag ggcgcggacc agggggttcg gcgtacggat tccggtcacg gtgcctccag
     3901 agcagcggtc aggtgttcca ttgtcgggca ggaaccgccg cccgggcgat ccggcccggg
     3961 cggtgctccg ccccactggc ctctgccccg gaaggcggcc ggcatggccg gtggggccgc
     4021 ccgtgtccgc cccggctcag agcggcagca ggtcgggccg cttggcgctg acgtggtcgc
     4081 cggaggagac gccccgcagc cggcggccga tccagggcac caggtactcg cgggcccact
     4141 ggatgtcgtc gcggcggccg tcgagcgggg tgcgcggcgg cagggtcggc cactcctcgt
     4201 cggggtcggc gggcacctcg accccgagga tctgaccggc gcgcagcgcg acccgggtgt
     4261 ggccctcggc cgacaggtgc agccggtcgg cgtcccaggc ccgccggtcc tgcacggagc
     4321 gcagcgacca gaggtcgagg acggggcagc cgtaccggtc ggcgatggcg cgcacgtgac
     4381 cgttgtaggt ggcgaccttg ccgcgcaggt gcttgaggac cggcaccccg cgggtgtcga
     4441 agccggtggt cagcacgacc gtgccgacgt ccgaggtgag ggcggtgacc gccttctcga
     4501 accgctcggc gaggtcgtcg gggtcggtgc cggggcggat cacgtcgttg ccgccggcgc
     4561 agaaggtcac caggtcgggc gagagctccc gggccctcgg cacctggtcg gcgacgatct
     4621 ggtcgagcag cttgccgcgc accgcgaggt tggcgtaccg gaaggcgtgt tcgggctgcc
     4681 ggtcggcgag caggacggcc aggcggtccg cccagcccac gaaggccccg tcgggtccag
     4741 ggtcccccac cccttcggtg aagctgtcgc cgactgccgc gtacgaggtg aaatctggcg
     4801 ctggggaagt cgtctctgct gtcacgggca catcattcac ctcgtgaagt gagttacgcc
     4861 accgtaggaa ggggttgacg cgggtgacaa acaccaccgg tcaaggttcc cccaaaggcg
     4921 gaataggtgc gcaggccacc catcgggctc gtggccgctc ccggcggcct cctcccgtgc
     4981 gccccgcggt gccgcccggc gcccctcgcg tgcgcgttcc cgcacgtcca cggcgttccc
     5041 gggtgcgaac acctgtcgta tcgtcgaggc gcgcccgccc gcacccgagc ggcggccgac
     5101 cgggaggagc ccacgtgacg cagcagtccc cgtcgacgag gtcggagtcg atgccggagc
     5161 cggagctgac cggggtgcgg aacttccgtg acgtcggtgg tctgccgacg gccgacggac
     5221 gccgcgtgcg tgccgggcag ctcttccgca gcggccacct cgcccacgcc accgaggccg
     5281 acacgggttt cctcagcgga ctcggcctgc acaccgtctt cgacttccgc aacagcgcgg
     5341 accgggccct ggacgggctc gacgtcgagc tgcccggggt gcgcaacgtc aacatcccgc
     5401 tgagcgaccc ggccgacggc gcgggcttct ggaagatggt ccgcgagggc gacctgcccc
     5461 agctccgctc gctgctcggc gacggcaagg ccgcgctacg gatgaccacc tcctaccgcg
     5521 agatgatcac cgggcgcacc accgagcaca gccgggtgct gcgctcgctc gccgaggaga
     5581 gcgtcccggc gctcatgcac tgcgcggccg gcaaggaccg ggccgggctc tcggtggcgg
     5641 tcacgctgct cgcgctcggc gtggaccgcg aggcgatcga ggcggactac ctggagtcca
     5701 acgcgcagca ccgccgctac cggatacgcc gggcctccga ctcccccgac gcgctctcgc
     5761 ccgaggtcat ggagctgctc agcccgctct tcgaggcccg cgccgagtac ctagccgcgg
     5821 ccttcgagac catcgacgcc acctggggcg gcaccgagcg gtacctgacc gacgggctgc
     5881 ggctcacccc cgagctccgc gaccggctgc acggccgcct gctggactga gcccggggct
     5941 cactgcgcct tgctgcccac ctcgaagagc aggtagatga agccggccag gaggtggccg
     6001 accaccacgt agatcaggag cctgatccac aggctgggcg gcagccgctc ctccatgtcc
     6061 cggccggccc gggcgggagc ctgctcggcg ggggcgccgg gctcggtttc gggtcgctcg
     6121 ctcatgcggg gcctttcggg ttcgggtgtc ccgggccgag gcacggggcg cccgggctct
     6181 ggagcagggt gtggacgaag aggagttcgg cgccgtcggc gtcggcggcg ccgatccggt
     6241 gcggggtgag cgagtcgaag tgggccccgt cgccggggtg cagcagatgc tcgctctccc
     6301 ccaggcgcag ccgcagccgc ccgcgcagca cgtgcagcca ctcctcgccg gggtggaccc
     6361 gcaccatgtc gccctgcgcg ccgtagggca cacgtacccg cagcgcctgc atggcgcgcc
     6421 cggacccgcc ggcgggccag tacgtccagc cgccggcggg ggccggttcg gcctcggcgc
     6481 cccggatgac ggcgtgctgt tcgccacccg tctcaccgag cagggcggag acggtcgtac
     6541 cgtagacacg ggccagtgcg aggagcatcg gcagcgaggg ctggcgctgc ccggtctcca
     6601 gccgggagag gtgagccgcc gacagtccgg cggcacgggc cgcggtctcc agggtgtgac
     6661 cggcgcggcg ccgcagctca cgcagctggg gcgcgacggc ggggagcgcg gccgggtcgt
     6721 ccggacggtc ggtggtcatg gttcgattga gccagattca tgcctcaggg acaagtttct
     6781 tgtctaagag gcaaaccgct cgggcgtcag cggtggacca ccgcctgccg gaccagggtc
     6841 cggccgaact cccacagcag cccgccgtcc tgcgcctcgt ccatgacctg cgtgaacgcg
     6901 tcgacgaagc ggtccacgtc cgcctcgtcc accaccagcg gcgggatcag cttgatgact
     6961 tcgaggtggt cgccggagac ctgggtgagg atgcggtgcc ggtgcagcag cggtgccacc
     7021 accatctgcg cgaagagccc cttgcgggcc gcctggagca tcgcccaccg gctgcgcagc
     7081 cgcagcgact cgggccgccc gaactcgatg ccgatcatca ggccgcgccc gcgcacctcg
     7141 tgcagcagct cgtagcgcgg gaccagggcg gcgaggcgcg agcgcagccg ctcccccacc
     7201 cgccggacgt gggccaccgt gtcctcgcgc tccatgacgt cgaggacggc gagcccggcg
     7261 gccatcgcct gggcgttggc gccgaagctc gccgagtgga cgaggacccg gtccatcgag
     7321 gagtacacct tggcgaagac ctcgtcggtg ccgagcgtgg cgccgaccgg gacgtacccg
     7381 ccggagagcg ccttcgccag gcagaccagg tcgggctcga cgccgtcctc gtgctggtgg
     7441 gcgtggaagt cgccggtgcg gccgagaccg gtctgcacct cgtcggcgat gagcagcgcc
     7501 ttgtgccggt ggaggagttc ctgggcggcg cgcaggtagc cgggcggggc ggcgtgcacg
     7561 cccttgccct ggacgggctc gacgatcagg ccggccacgt ccccggcgcg cagctcgcgg
     7621 cggagcgcgt cgaggtcgcc gagggggacg gcggtgtcgg ggagcagcgg cccgaagccg
     7681 tcgcggaagg agcgctcgcc gttgaccgag agggcgccgg tggtcaggcc gtggaaggag
     7741 tgcgcgcagt gcaggacgcg ggggcggccg gtggcgcgcc gggcgaactt cagcgcggtc
     7801 tccacggcct cggtaccgct gctgcagaag aaggcccggt gcaggtgcgg ggtgtacgcg
     7861 agcagccgct cggcgagcag acccggcagc ggagggcagt cgaagcgggt gaggtcgggc
     7921 agcgagaggt cgaggacgtc gtgcagggcc tggcggatca ccgggtggtg gcggccgagg
     7981 cccatcacgc cgaacccggc gagcatgtcg aggtggtcgt tgccctcggc gtcccagaag
     8041 tgggcgccct cggcgcgctc gtagaccttg tcgaagccca gggtgcggag catccggggc
     8101 agctgcgggt tgaggtggcg ggcgtgcagc gcgtaccgct cgccgccgcg ttcggcgagg
     8161 agccgccgca ggtcgaagcc gggcgccggc ccggcaccgg tcgccggtgt gccgccgtcg
     8221 acggtggtca tgggtgggtc cccctctcgg tggaacgcac gcggggccgg acggctcagt
     8281 gccgcccggc cccggcgggc gtcaggcgcg gttgctggtg acggtctcgc gggcggcgcg
     8341 cagcgactcc ttgagggagc ccatggtcgc gaggacggcc gtcggttcgt agccgcagtg
     8401 cgccatgcag ttggcgcagc gggggtcctt gccccggccg tacttctccc agtcggtctc
     8461 ctcgatgagc tggcggtacg tggggacgta gccgtcgctc atcaggtagc aggggcgctg
     8521 ccagccgaag agggagtagt tggggatggc ccaggcggtg caggcgaagt ccgccttgcc
     8581 ctccaggaag tccaggaaga gcggggagtg gttgagacgc cagcggcggc ggttgccgtc
     8641 cgcgaaggtc ttgcggaaca gctcgcgggt ctgctcgacg ccgaggaagt gctcctggtc
     8701 gggtgccttc tcgtaggcgt aggcgggcga gatcatcatc tcgtcgacct ggaggtcgtc
     8761 gttgaggtag ttgagcacct cgatgatggt ctgcggggtg tcggtgttga agaaggtcga
     8821 gttggtggtg acgcggaagc cgcggcgctt ggcctccttg atcgccgcga cggcctcgtc
     8881 gaagacgccc tccttcgcca ccgactcgtc gtgccgctcc cgcagcccgt cgatgtgcac
     8941 ggcgaacgcg aagtacgggg agggggtgaa cttgtccatc ttcttacgca tcagcatggc
     9001 gttggtgcag aggaagacgt acttgcgttt ggcgacgagc tgattcacga tctcgtcgat
     9061 ctgcgggtgc atcaggggct cgccgccggc gatggagacc atcggcgccc ccgactccag
     9121 gaccgcgccg acggcctggg cgaccggcat gcgctgcttg aggacaccgg cggggtgctg
     9181 gatcttgccg cacccctcac aggcgaggtt gcaggcgaac aggggctcca attcgacgat
     9241 gagcgggaat ttctcccgcc tgcgcagctt ctgttcggcg agatacgtcg ccaccttgat
     9301 ggtctggcgg agcggcatgg ccatctggct cacctccggg ggagcagcga ggaacggtgc
     9361 cattcgtaga aagcggggat cacggcacgg agtacacgga aagccgatat tccaccgcgt
     9421 accgttccga tccggaccag ctcatgctct ggagcgtcca cgaccacccg gacggccgca
     9481 accgggcgcg gtccggccag ccgggcggtg tacagggtgg cggcggactc catgtcgacg
     9541 gcgacggccc cctgcgaccg cagccgggcc cgctcagcgc cgcgcaccac gtggtcgcag
     9601 ccggtgagcg ggccggtgtg cacggtgcgc cccggcaccg cgcgggccac cgccgcggcc
     9661 agtacgccgg cctcggcgca acgggtgacg ccgcgcgggt cgcggacctc gtcggcgacg
     9721 accaggtcac cggggtgcat gcccgcgccc aggcccgcgc agaacccggt ggcgaccacc
     9781 ccggcgcgcg ccagcgccgg gtcgcgcagc gcctcggcga cggcccggcc ggccgcctcg
     9841 ggccccatgc cggtgcggag cacccgggtc ggggtgtccg cgggggcgcg ggtgccggtg
     9901 cgcagggcga gccgttcgat ggtgagggcg caggcgatga ccaggggcgc cgggccggcc
     9961 gccgggcccg gcaggggccc ggcggccgcg gggcgcgtca tcaggcaccc tcgggtgctg
    10021 ctccgcgggt gtaccggccc agcgccgtga gcgggaagac ctgccggtac aggtggtagt
    10081 tgatggagaa gtcccagggg aagccggtac cggtgtagta cggctcctcc cagctgccgt
    10141 cctcgtgctg ggtctcggcc aggaaggtga cgccgcgccg ggcggccctg ctctcccgct
    10201 ccccggccgc gaggagcgcc atcagggccc agccggtctg ggaggcggtg gaggcgccgc
    10261 gggccatccg gccctgctcg cggtaggagc gcaggtcctc gccccagccg ccgtcgtcgt
    10321 tctgcaccga ctccagccag gccacggcgc ggcggatcgc cgggtgggtg gtgggcagcc
    10381 cggcgtcgac cagggcgggg acggccgagc cggtgccgta gaggtagttg acgccccagc
    10441 ggccgaacca ggcgccgctc ggttcctgct cggcgaggag ccagtcgacg gcgcggcggg
    10501 tgcgcgggtc agcggcgagt ccttcggcgg ccagcatctc caccacgtgg gcggtgacgt
    10561 cggcggaggg cgggtcgacg acctcgccga agtcgcagaa gggcagccgg ttggggagcg
    10621 agctggtgtt gtcgacgtcg aaggcgcccc aggcgccgtt cttcgactgc atgccgaggt
    10681 tccagcgcac ccccagcgag atcgcccgct ccatgcgggc ggtgtcgggg tggcggaccc
    10741 ggcgcagggc gagcaccacc tcggcggtgt cgtcgatgtc cgggtagttg tcgttgtgga
    10801 actcgaaggc ccagccgccg ggggccaggt tcgggcggcg caccgaccag tcgcccggcc
    10861 gctcgatctg ctcgtcgagc atccagtcgg cggcgcggac cagctgcggg tggtcggcgg
    10921 ggaccccggc atcggccagc gcgatggtgg cgaggcaggt gtcccagacg ggcgactggc
    10981 acgcctcgac catccgggag ccgtcctcgc gggtgagcgt gaagcggtcc agggactcca
    11041 ggccggcccg catgacgggg tggccgaggt cgtagccgag caggtgcagg gcgatcatcg
    11101 agtagacggc cggcggctgg atgccacccc agcagccgtc gttctcctgc cgctcgacga
    11161 tccaccggcc cgcggtggcc atggcggccc tgcgcagggc gcggggggcg accttgcggt
    11221 acgcgtgcag ggcgcggtcc agccgctgga aggcgccgtt ccagctcgcc aggggggcga
    11281 agcgggcgcg gggcgccgga tcggccgggt cggtgtgcag ctcgtccagg gggaacgggg
    11341 cggggcgcac ggggcgcttg gcggagacga cggtgagcgg aacgatggtc tgccgggccc
    11401 agcagccgaa gtcgtagatg ttcagcgggg cccacggcgg caggaagatc agctcgggcg
    11461 gcagctcggg gagccggtcc cagggccacc agccgaagag ggcgagccag atccgggtga
    11521 agacccgggc ctcggcgatg ccgccctggg agcggaccca gtgggcggcg cgggtcatgt
    11581 gcggggcgtc ggggctgtcc ccggcgagcc gcagcgcgac gtacgcctcg acggtggtgg
    11641 agaggtcggg cgggccgccg tggaaggtgg cccaggtgcc gtcctcgcgc tgttcgccgc
    11701 ggatgaagag ggcggcggag cgggtggtgg cctcgtcgcg gatgccgagg aactggcgga
    11761 gcagcaggtc ctcggcgtcc atcgtgacgt tggtgtcgag gtctcccttc caccagccct
    11821 cggggctctg gaggcccagg aggtggtcgg cggcgcgggc cctggcccgc tccgcggcgg
    11881 cctcgacggc ggccccgtcg agggcggcgg tgtcggtggt ggccgcagtg gtacgggccg
    11941 gggcggggcg ggagggcgcg gccccggccg gtccgttggt cgtcgctgtc atggcgtccc
    12001 cctggtgcag tggtcggtct gcgtgtgctc gggggtgtgc cgtcggcccg cgccggatca
    12061 gggcgcgggc cgccgacagc gcgtcatatg tggcgggggg tgccgttact gccggtgacc
    12121 gggggcaggg gaagggcgcg cgaggccggg caggcgtcgc gcgtcgcggg ttccgtggcg
    12181 atggtgatca tctcttccgt acgacgacga agtcggcgag ggcggtgagc tgctcgcgta
    12241 cgtggtcggg catgccgacg ccggagaggg cctcgatggc gacggtgtgc tggcggcggg
    12301 cctcggcctc ggtccaggcg cggccgccgg cctcctcgat gagggcggcg cgggcggcga
    12361 actcgtcctc cgagaagttc tcgaagtcgt tggccttggc gtcggcggcg agcagcgagc
    12421 cgagccgctc ggcggcgggc ccctcggcgg cgagggcggc gacgacgggc agcgacttct
    12481 tgcgctgcct gaggtcgctc caggtctgct tgccggtggc ctccgggtcg ccccagatgc
    12541 cgaggaggtc gtcgacggcc tggaaggcga ggccgaggtg gtagccgtac cgctccaggg
    12601 cgtcggcggt gcggtcgtcg gcgccgccga ggacggcgcc gatggagacg gcgcaggcga
    12661 gcagggcgcc ggtcttgttg ccctccatct ccaggcactc ctcgacgctg acgcgctcgc
    12721 ggtgctcgta ggagatgtcc tgggcctggc cgtcgatgag ggcgcggctg gcggtggtca
    12781 ggcggcgggc ggcgcgcccg gcctccaggg tgccgagctc cagcaggatc tcgttggcca
    12841 gggcgaagag cgcgtcgccg acgaggatgg cctgggccgg gccgtgcacc ttccagacgg
    12901 tgtcgcggtg gcggcgctgc tcgtcgccgt ccatcaggtc gtcgtggagg agcgagaagt
    12961 tgtggaccag ctccacggcg accgcgccgg ggatgccggc ctcgggcgcc gccccggccg
    13021 cctcggcgga gagcagcgcg agggcgggcc ggacggcctt gccgccgtcg ccctcggcgg
    13081 ggtggcccgc ggcgtcgatc cagccgaagt ggtaggcggc gacggtgtcc atgggcgggg
    13141 cgagacgctc gatggcggcc ttcagcacgg gcgtggcgag ggtacggcca cgctccagca
    13201 gggcggccac gtccgtggtg tcacggtccg cgtcggccgt gggcacagtc ggcacagttg
    13261 ctcctttgtc tccggtacgg aaggtcaggg ggtcaggggc gcggcggggc ggcccggggc
    13321 gggcggctca cgcggcctcg tcgaagacgg gggcgggccg gggccggccg agcgccccca
    13381 gggcgtccga ggcggcgttc agcccgctgc gtacggcgcc ctccatggtg gcgggccagc
    13441 cggtggcggt ccatgccccg gcgaggtgca ggccgggcag gcgggtggcg gggccgggcc
    13501 gcagggcgcc gacgccgggg accgccgcga aggtcgcggt gcgttcgcgg gtgacgaaga
    13561 agtcctcgac gcgggcggtg cgggcggcgg gcagcagccg ctccagctcc ggcaggtagc
    13621 gggcgcgcag gtcggcgacg ggggtgtcga tctcggcctg ggcggtcgac tgggagagcg
    13681 cgaggtactg gccgtggtcg agcccggacg cctcggtgcg gtcgaagacc cactgcaccg
    13741 gcccgtcgag ggcggtgaag aaggggcgcc ggacgacctt gcggtcgtag aggacgtgga
    13801 tgttgatgat gggggcggtg ccgatccggg tgagcttctc cggctcgtcg agggcgccgc
    13861 cggggagcag ctcgtgggtc tcggccgggg gcacggcgag gacgacggtg tcggcggtga
    13921 gcgtctcgtc gccggtctcc acctgccagc gggcgccctc gccgccgggc gtgacgccgc
    13981 gcacgcgggc ccggagcacg gtgcgtacgc ccgccttgtc cagggaggtc agggcccggg
    14041 tgtggtgcag ttcgccgagc gggacgtggg cccagccgat gtcggcggcg ccggcgtcgg
    14101 agagcaggcc ggtcctgaac accttggcgg ccagggcgag ggaggcgtcg tcggcggcgg
    14161 cgttgagggt ggcgacgccg acgaggtccc agagggcggc gacggcgcgc gggctctgcc
    14221 cgtggcggcg cagccagctg ccgaagtcct gccggtcgag ggcggggtct gcggggtcga
    14281 ggcggcgcag ggcgagcgcg gcgcggccga cggcggcctt ctcggcgagg ctcaggtgcg
    14341 ggtagcgggc gaggctcggg ccgaggtgga acgggacggg cagggcgttg cgccgcagcc
    14401 tgccgaggcg cccgcggccg gcgtcgagga cggggacgtc gaggcggtcc tggacggggg
    14461 cgagggcggc gccgtcgacc cggtcgagga accagcggta ggcggtgcag cagcgcaggt
    14521 agacgtgctg gccgttgtcg acggtgaggc cgccgcgctg gaaggagaag gcgaggccgc
    14581 cgaggcgggg gcggccctcc aggagggtga cgcgcactcc cgcgtcggcg agggcgaggg
    14641 cggcggcggt gccggcgagg cccccgccga cgacgaccgc ctcccgggcg gcggcggtgg
    14701 tcatgcgcgc ctccgtccgg cctggcggcc gatctgccgg gcgtcgaagc cggagaggcc
    14761 gcgcacggcg acgtacgcct tctcgtggcc ggggagggag acgcggccgc gcaggacggc
    14821 cagcgggtcg cgctcgatgc ggtcgagcag gcgccggtag atcccggcca tggcggcgac
    14881 gcaggcgccg ctgcggcggt cgagcatcgg cagcagccgg tacccctcgg cgaacagggc
    14941 gcgggcgcgg cggacctcga agtggaccag cccggggaag tccgacccgg cgggcgggtg
    15001 gggcccgtcg aagccgtcgg agcagccgaa cttggcgagg tcgtcggcgg gcaggtaggt
    15061 gcggccgttg ccggcgtcct cgcggacgtc gcggaggatg ttggtgagct ggagggcgag
    15121 gccgagggtg tcggcgtact cggcggcctt ctcggtctgc ggggcgccgg gggcggggcc
    15181 gaagatgccg agcgagagcc ggccgatggc tccggcgacg cagcggcagt agagcttgag
    15241 gtcgtcccag gtctcgtagg tgacgccctt gacgtccatg aggacgccgt cgatcagctc
    15301 gtcgaggccg ccgagcggga tggggaagcg gcgggcggcg tcggcgaggg ccacggcgac
    15361 ggggtcggtg tcgtcctcgt cgaccttgcc gtcgcggatg cggtcgagga tgtcgcgggt
    15421 ggcgccgagc cggtccgcct tcacctcggg cgccagcgtg ccgtcgccga tgtcgtccac
    15481 ccgccgcgag aacgcgtaga gcgcggacat cgcgcggcgc tcggcgaccg gcagcagccg
    15541 gatgccgtag gcgaagttac gggcctcgga cccggtgacg gtctcgcagt agctgtacgc
    15601 ggcgaggacc ggtgcgggca gggagatgct gtcctccacg gtcgggctca cctctctcct
    15661 cgcagggccg ctcccacctc gcgcaggagc ctgggcttgg tgggcctcgg cgggccgggc
    15721 aggacgtcgt acccggcgtc ggtgaccgcg gccagggccg cccggccgcc gccgacgaag
    15781 ccggcgagca gcagccgcag ccggccgtgc acgctcgcga tcagcgggcc gccctcggcc
    15841 agcagctccc cggcgcgcga cgcctcgtag gcgacaagcg cgcgcaggga ggcggaggcg
    15901 gtgggggcgg cgaggtcgct ctcctctaca cggaagcgct tcaggtcctc ggcgggcagg
    15961 tagatccggt cccgggcgag gtcctcggcg acgtcctgga ggtgctcgac gatctgcagg
    16021 ccggtgcaga cggcgtccga gcggcgcacg cgctcgggcg tcagggtgcc ggtgaggccg
    16081 aggacgaggt ggccgaccgg gttggccgac agctcgcagt acgcggcgag gtcgtcccag
    16141 gtctcgtacc gggtgaccag ctggtcctgg cggttggcct ggatcagggc gcggaagggt
    16201 tcgggggtga ggccgtgggc gcggaccacc gggcgcaggg cggcgaccag cgggtgggcg
    16261 gggccgggtc cggtggtggc gaagacccgg gcgaggtcgg cctccagggc gtccagcagg
    16321 gtgaggcggt cctcggccgc gctcccctcg acgcccagga ggcgggcgtc ggcgccgccg
    16381 ggggtgaggt cgccgtcgcc gatgtcgtcg acgaggcggg cgtagccgta gacggccatc
    16441 aggccccggc gccaggcgcg cgggacgaag aagggggcca cggggaagtt ctccgcggcg
    16501 gccttgtcga gggtggcgcg taccggggcg ccgtgctgcg ccctgcccgg tgcggtcatc
    16561 gccggctgcc ccgcgccgga acggcacaag ccgcgtggag ccggagatca cccgtagcca
    16621 ttgccgtcac atctcccgtt ctacactgcc gacccaaaac atcccttttc ggacacgccg
    16681 cccgccatgg cggtgatcgc catctgttcg acttcgggag acgggtgcca tatcgccgca
    16741 actcacgcga atcagcaccg gtacagctta cgcggcacgc gcgcccgtgg tgcgccgggg
    16801 tgttcgccag gtcacagcgc gccccccgac ctgggcaact ccccgccggc ccgccgagtt
    16861 cccgtgcagc ggaacaggcc cctccgcacg ccggggcccc ggcccgcccc cggtacggga
    16921 ggcggggccg gggccccctt gcacgccgtg cccgccgtcg cgggcccgtc gctacttgct
    16981 ggtgaacttc tcgtactcct tgaggacctc ggccgtcggg ccgtccagcc gcagctcacc
    17041 gtgttccagc cagatcaccc ggtcacaggt gtcccggatg gacttgttgt tgtggctgac
    17101 caggaagacc gtgccggcct ccttgcgcag ctccctgatg cgcgcctcgg agcgcttctg
    17161 gaacttcttg tcaccggtgg ccagcgcctc gtcgatcatg aggacgtcgt ggtccttggc
    17221 ggcggcgatg gagaaccgca gccgggccgc catgcccgag gagtaggtgc gcatcggcag
    17281 ggtgatgaag tcgcccttct cgttgatccc ggagaagtcg acgatgccct ggtagcgctc
    17341 cctgatctgc tcgcgggtca tgcccatcgc gaggccgccg agcatcacgt tccgctcgcc
    17401 ggtcaggtcg ttcatcagcg ccgcgttgac gccgaggagc gagggctggc cgtcggtgta
    17461 gaccttgccg ctctccgcgg gcagcaggcc ggcgaccgcc ttgagcagcg tcgacttgcc
    17521 cgagccgttg gagccgatca ggccgatcgc ctcgccccgg tacgcggtga agctgacccc
    17581 gcgcacggcg tgcaccttgc ggacgccgcg ctcctcgccg cgcttgagga tgcggctgag
    17641 ggcggcggtg gcgctgccct tgccgccctt ggtgccgttg acccggtaga cgatgtgcag
    17701 gtcgtccgcg atcaccgtgg gggtgcgggg gccgcccggg gcgccctggt ccacgtcagc
    17761 ctcggccata gcgctcctcc gacttccaga agtagacgaa tccggcgacg cccgcgacca
    17821 gcgcccagcc cagggcgatg gcccagacgt gggcgggcag gtacttggcg gtgtagtcgt
    17881 cgatcagggc gaaccggacc aggtccatgt agacggcggc cgggttccac tggaggacgt
    17941 cgctcagcca gtgcggcagc cggtcgttgc gggccagcat caccgggatg gagaacatga
    18001 cgcccgaggc gtacatccag gtgcgcatga cgaacggcat gagctgggcg aggtccgggg
    18061 tcttgctgcc cagccgggcg aagatcagcg cgagaccggt gttgaagacg aactggagcg
    18121 ccagcgccgg caggaccagc agccacgacc aggtggggta cgaaccgaag cccatgacga
    18181 tcgcgaccag cacgatcatc gagaagagca gctgctggag ctgctggagc gagaaggaga
    18241 tcggcagcga ggcccggggg aagtgcaggg ccctgaccag gccgaggttg cccgagatgg
    18301 agcgcacccc ggacatgacc gagctctggg tgaaggtgaa gacgaagacg ccggtcacca
    18361 ggaagggcac gtacacgtgc tccgggatgc cccgcttggc atccagcagc acgccgaaga
    18421 tgaagaagta gaccgccgcg ttcagcagcg gcgtcaccac ctgccacagc tggccgagct
    18481 tcgcctggct gtactgggcg gtgagcttgg cctgcgagaa ggcgacgatg aagtggcggc
    18541 ggccccagag ctgcttgacg taggcgagca ggccgggccg tgccccgctg accgacagac
    18601 cgtacttctc cgcgagctgg gccggggaga gcccgtcgtc gggggagggc ggagcagcac
    18661 tcaccgcgac accaccgtcc tgcgttgtct cactcacaag gggaaacttt cgtcttcggg
    18721 atgcaccgcc ggaacccctg gcagcaccgg gcggcacggg ggtggtccgc ggtcggggac
    18781 cggtacgggc cgaatggtct cagacccgag cttgtcagat gacgggaggt cggcccagcc
    18841 gggtgagccg ccacacagtg cgccacttca tgggccgccg gggccccgcg gaggaggtcc
    18901 agccctcctt gaacccgccg aaccacgcct tcagcgcggc ccccgagggg cgccgcagca
    18961 gggtgagcag cagccagacc ccgaggtaga ccgggaccag cgggaggggc aggttgcggc
    19021 gggccagcca gacccggttg cgggccacca tgcggtggta gaccgcgtgc cgggaggggg
    19081 cggtggtcgg gtggtacagc accatgtcgg agcggtagtc gatctgccac ccggcgttca
    19141 gcgcccgcca ggcgaggtcg gtctcctcgt gggcgtagaa gaagtcggcg ggcagcagcc
    19201 ccgcttcggc gaagacccgg gtgcggacgg cgttggcgcc gccgaggaag gtcgtcaccc
    19261 gcgaggagcg catcgggtcc gaggcacgga gccgggggac gtggcgccgc tgggtctccc
    19321 ccgtgtccgg gtcggcgatg cggaaggaga cgatgcccag ctccgggtcg gcggtgaacg
    19381 cctcgcggca cagctcggcg gtgtcggtgc gcgcgaggag cccgtcgtcg tccaggaaga
    19441 gcaggatgtc gacctcgcgt ccggcggggc cgaacatctc gatgccgacg ttccgcccgc
    19501 cggggatgcc gaggttctcg ggcagctcgg tggtgcggac gccctcgggg acctccggca
    19561 ccggcgagcc gttgccgacc acggcgatct ggaccgggtc gccgtcctgc ttggcgaccg
    19621 agtcgatgag cgcgcgcagt tcctcgggcc ggttgcccat ggtgatgatg acggcgccga
    19681 ccgtcgggga ggtgctgttc acggcggtca cctcagcctg ctcgacacga ggatggacac
    19741 caggtgcaga agggtctgca gcagggcgat gccggccagg acggcgatgc ccaggcgggt
    19801 gaagaagagg tcgccgcgga tctggtcggc caccgcgagg acgatgatca gcagcgaggc
    19861 ctcgatgccg aggaccaggc ggtggaactt gagcgcggcc gcggccttgc gggcgaaggc
    19921 caccttggag gagcgcggct cggaggccgc ctccttgacc ggcggcagcc cgccctggtg
    19981 ccgggcgacg ccgaccaggt cggtctcggc cttgatcagg atcgcgccga gcgccgccag
    20041 ggtgccgagg aaggcccaca gccagtcgat ccggccgctc ccccacaggt cggcgccgcg
    20101 caggccgagg ccgaccagga ccgcggcgtc gcacaggtag gcgccgacgc ggtccaggta
    20161 gacaccgccg agggagaact gcttcttcca gcgggcgacc tcgccgtcca cgcagtccag
    20221 cagcaggtac agctggacca tcagggcgcc caggagggcg ccccagatgc ccggcaccag
    20281 cagcgccggg caggccagca cgccgaagac cgtcatcagg taggtcagct ggttgggcgt
    20341 gatgcgggtg ggcaccacgt accggtcgac ccgcagcgag atctcccgca tgtacaggcg
    20401 tcccgcccag tgctcaccgc tgcgccggtc cttcaccccg gcggggtgca cgaccgggcg
    20461 gagttcagct accgatggcc ttggcatagt cggcgtaagc gtccttgatc tggtcggtgg
    20521 agaggttgag gtgctccagg atcgtgtacc ggcccggccg ggtctgcgga gcgaactcca
    20581 cgacctggac gaactcgtcc acggtgaaac cgatgtccgc cggcaccacg ggcagcccgt
    20641 gccgcctgag gacctcggcc atctgcgccg actccgcggg ggcaccgcgc aggtgcatcg
    20701 cgaaggccgc ccccatgccg cactgctcgc cgtggctggc cgcgcgcttg gggaagagca
    20761 ggtcgaaggc gtggttgatc tcgtggcagg cgccggaggc ggggcggctg tcgcccgcca
    20821 ccgacatgga gatgccggtg agcaccagtc cttcggccag gacctggagg aagccgtcgt
    20881 cgccgacgtc ccccgggtgg cggagcaccg cctcgccggc ctggcgggcc atggcggccg
    20941 ccagaccgtc gatgtcctcg ccgcggaccc gggccgacag ctcccagtcc gcgacggcgg
    21001 agatgttcga cagggcgtcc ccgatgcccg agcgcacgaa ccgcgccggg gcctcgcgga
    21061 tgatgtccag gtcgatgacg acgccgatgg ggttgggcac cccgtacgat ccccggcccg
    21121 cgtcgttgtc gagggtggcg accggcgagc agaggccgtc gtgcgacagg ttggtcgcga
    21181 cggcgaccag cggcaggccg atgcgggccg cggcgaactt ggcgcagtcg atgatcttgc
    21241 cgccgccgag gccgacgacc gcgtcgtagc ggcccgactt catggcgtcg gccagcttga
    21301 ccgcgtcgtc cagggtgccg ccgcccacct cgtaccagct cgccccgggc agggccgggg
    21361 agagccgctc gcgcaggcgg gcgcccgagc ctccgctgat cgctatcgcg agcttgccgg
    21421 aggaggagat ccgctggtcg gcgaggaccg aggcgagatc gttgagggcg ccgcgccgga
    21481 tgtcgacgac gaggggcgag gggatcaggc gcgtcagtac cggcacgcga tctccctgcc
    21541 cttggcgagg tcctcgtggt tgtcgatctc gacccagctg acctcgccga tgggcgccac
    21601 gtcgatcttg aagccgcggt tgacgagctc ctggtagccg tcctcgtagt acagctgcgg
    21661 gtcgcgctcg aaggtggtgc gcagcgcgtc ggccagctcc tcggccgcct cgccctcgat
    21721 gagggtgacg ccgatgtact cgccggtggc ctcggcgggg tccatcagct tggtgatgcg
    21781 ctggacgccc ttgtcggggt cgacgacgac cttcatctcc tcgtcggcga ggttcttgac
    21841 cgtgtcgagg gcgaggatga tcttctggcc gttgccgcgg gcggcgagca gcgtcttctc
    21901 gacggagacc gggtggacgg tgtcgccgtt ggcgaggatc acgccgtcct tgagggcgtc
    21961 acggccgcac cacagggagt aggcgttgtt ccactcctcg gccttgtcgt tgtcgatcag
    22021 cgtgatcttc aggccgtact tggcctccag cgcggccttg cgctcgtaga cggcctcctt
    22081 gcggtagccg acgatgacgc cgacctcctc caggccgatc tcggcgaagt tgccgagggt
    22141 gaggtcgagg acggtcaggc tctcctcgtc gccctcggga cccaccggca ccagggcctt
    22201 gggcagggtg tcggtgtagg gacgcagacg ccgtccggcg ccggccgcca gcacaaggcc
    22261 gatcatgcgg gttctccttc atcgtgtacg gcgggtgctc cggcggagac ccagaagcgg
    22321 atgctctcgg cgagcaccac gagtgccacg gccacggcga gaaccgtgag cgcgacggtg
    22381 aaacctgagg gggccagcag cgaggcggcc gtgacgagga ggacgcggcc ctcgtgcccg
    22441 ccggttgcgc ggaccagcgc gcggggcggc gcgccgctgc caccgcggat gcggtagacc
    22501 gtgtcgtagt gatggtaggc gaccgccgcg accagcccga aggccgccgg aagggctccg
    22561 gagtcgtcgg cgcgggcggc cagcagcagg atcactccgt actcggcggc ccggaagaag
    22621 ggcggcacga gccagtccag ggcgccggtg agcggccggg agacggcgag cgcggagcag
    22681 agcacgtaga cgacggcgcc gagcagcggg ccggcggaac cggccggggt gagggcggtc
    22741 accgcgacga ggatcacgcc gccgagggcc gccaccgccg gtgcggggag cttggcgaag
    22801 gggcgcaggc gcgggctcag cgcctcggcg agcgggccgc tgtcggcgag gtcggcaagg
    22861 gcctgggcgg cccggtcggt gcgctcggcc ttgcgggtca gcgagcgcag caggcggccg
    22921 gcggtggtgt aggcggcggc cagggcgcag ccgatcagca gcacgacgaa ggtgatgcgg
    22981 ggcgtggtga cggcggtgag gaccgcgatc agcgcccagc gctccccgat gggcagcacg
    23041 atcatgcggc gcagccacac ggtccagccg acgctgtcga ggcggccgga gagggcggcg
    23101 gtggggctgg tgttggcctc ggcgtcgtgg ttggcctcgt tgaaggagaa gtccacgacg
    23161 tgccggcagg tctggaggac catcgcgccg agcgccagcg cccacacgtc gtccccgccg
    23221 cgcgccgcgc cgagggcgag cccggcgtag tacgcgtact ccttggcccg gtcgaaggtg
    23281 gcgtcgagcc acgcgccgag ggtggagtac tggagggagt agcgggcgag ctggccgtcg
    23341 gtgcagtcca gcacgaagga gaagaggagg agcagcccgg cggcgacgaa gccggcccgg
    23401 gtgccggtgg ccgcgcagcc ggccgcgatc agcgcggtga ccagcgaggc ggtggtcacc
    23461 tggttggggg tgaggccgcg ccgggcgcac cagcgggcca ggtaccgcga gtaggggctg
    23521 atgcagtacg tggtgaagaa gccgtcgcgg gacttgacgg cggtccgcag ccggatcgcc
    23581 tcgtcgtcga cggcggcgac ggcctggcgg gcctcgctgc gctcctgcgg ggcgagcggg
    23641 acccgggcga cgagggcacc gagctcgggc cggtggacgg cgacgccctc ggcctgcagg
    23701 gcgccggcca gccggtcggg cagcccggtg ccggtgcgca ccgcggcgcc gccgggggcg
    23761 ggccggccgg cctcggcctc cagggcccgg gtgagggcgg cgcgggaggc gtcctgcacg
    23821 gtgacggcgc cggggacggt accggccggg aagcgggggt cggtcaggcc caggcgcagg
    23881 gcgtggaggt ggccgacgaa gccggcgtcg accagggcga cgcggccggt gggcacggta
    23941 cggagcaggg cggctgcctc ggcggcgtcg gaggcggtcc gcacgtcgaa gcccagcgtc
    24001 cgcagttcgc cctcgatcgg cgacccgggg accggctgac cggtgacgat ggcggtcgac
    24061 agacgaactc actccttggg tgccggtgcg gtccgcgccg gacagctcgg gtgcctgtga
    24121 caacggcctg gcggcacgtc ggctgaggct atcggacggc ggggagcccg cgttcaccgc
    24181 ccgttcggta cctgttcgca tcccgtgcgg gggcacgcag ggcgggcgtg gccgggcgca
    24241 cgcggcttcc ccgggacggg gggcgcggcg cggggccgcc gccatcatgg tcgatcaact
    24301 gcccggccga caaaccgcgt cccgccttcc gccgctggtc gcgacgcatg gccccgcttc
    24361 ggtcaccttc gcccgttctc tccgcacacc ggccggaagg cacgattccg ccaggcggcg
    24421 gcaggggctc cccgaacggg tcgaccaggg cctccaggag ccctgcgagg cgctgacctg
    24481 caccgcgttt ccgcaggtca gggggaatga caacggtatt cagcgccgtg ttgccggata
    24541 ccccccaccc gtagttcact gtggtcggcc gacgccactg acgaagcgac cgacgaggca
    24601 aaggacacgt cccatggggg ctgggcacga tcacggacac acacacggtc ccgccaccgg
    24661 gacggccgcc tcggcccacc ggggcaggct gcggatcgcg ctgggcatca cgctcttcgt
    24721 gatggtggcg gagatcgtcg gcggtctgct ggccgactcg ctggccctgg tcgccgacgc
    24781 cgcccacatg gccaccgacg cgctgggcct gggcatggcg ctgctcgcca tccacttcgc
    24841 caaccgcccg ccgagcgaga agcgcacctt cggcttcgcc cgcgcggaga tactcgcggc
    24901 gctcgccaac tgcctcctgc tcctcggcgt cggcggctac gtggtctacg aggcggtgga
    24961 gcggttcttc ttcaccccgg ccgagacctc ggggccgctg gcgctggcct tcggcgcggt
    25021 gggcctgctg gccaacgtcg tctcgctctc cctgctgatg cgcggccagc gggagagcct
    25081 caacgtgcgc ggcgccttcc tggaggtggc cgccgacgcg ctgggctcgg tggcggtcat
    25141 cctctcggcc ctggtcatca tggccaccgg ctggcaggcg gccgacccga tcgcctcgct
    25201 gctgatcggc gcgatgatcg tgccgcgcac cctgcggctg ctgcgggaga cgctcgacat
    25261 cctgctggag gcggcgccca agggcgtcga catggcggag gtgcggcgcc acatggagga
    25321 gctgcccggc gtggtcggcg tgcacgacct gcacgcctgg accatcacct cgggcatgcc
    25381 ggtcctctcc gcgcacgtgg tcgtcgaggc ggaccagctg gacgccgccg cccacgagaa
    25441 gctgctgcac gaactccagg agtgcctggg cggccacttc gacgtggagc actgcacctt
    25501 ccagctggaa ccttcgggcc acgcgccgca cgaggcgggg ctctgccact gagccccgga
    25561 agcggcccgg gggatgtcac aggatcgtca caggtcgccc ggcgggccgc cggggcgccc
    25621 ggaccgggcc ggggtgcgcc ggagccatcc gccgcctccg ccccgccggc ggacaggggt
    25681 ccgcgccgcg ccacgccctc ccggaccgcc ccgcgcccgc tcctgaccgg cgggtacgga
    25741 ccgcgtaccg gccgccagga agcggacggg tagcgtccga tccgggcacg ctgggcacgg
    25801 caggtgccca gagcgccgga tttgtgcggc agacttgggc gctcaggacc gaagcgaagg
    25861 atgggtatgc cgatcacacc tgccaccgcg gtgagccgct cgtcggacga ctccccggag
    25921 gccgtcattc tgctcgaact ggtcgacgag gacggcaaca ccatcggcac ggcggagaag
    25981 ctctccgccc accaggcgcc cggccgcctg caccgggcct tctccgtctt cctcttcgac
    26041 gagcggggcc gcctgctgct ccagcagcgg gccctgggca agtaccactc ccccggcgtc
    26101 tggtccaaca cctgctgcgg ccacccctac ccgggcgagg cgccgttcgc cgccgccgcc
    26161 cggcgcacct tcgaggagct gggggtctcc cccgccctgc tgggcgaggc cggcacggtc
    26221 cgctacaacc acccggaccc cgcctcgggc ctggtggagc aggagtacaa ccacctcttc
    26281 gtcgggctgg tccgcgatcc gctgcggccc gacccggagg aggtcggcga caccgtcttc
    26341 gtcaccccgg ccgagctggc cgagcggcac gaggccgggc ccttctcggc ctggttcatg
    26401 accgtcctgg acgcggcgcg cccggcgatc cgcgagctga ccggggacag caccggctgg
    26461 tgaggctcag cctccggggg ccgggagcac cggcgcgccg cccgcccccg ggcccagcgg
    26521 cagcgccgcc cagatgatct tcccgccggc cgcggtgtg
//
