LOCUS       NZ_CP042266            25159 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces qinzhouensis strain SSL-25 chromosome, complete genome.
ACCESSION   NZ_CP042266
VERSION     NZ_CP042266.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qinzhouensis
  ORGANISM  Streptomyces qinzhouensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8146484)
  AUTHORS   Zhu,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2019) School of Life Science, Hunan University of
            Science and Technology, He Ping Street, Xiangtan, Hunan 411201,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007856155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 04:30:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,577
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 28 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 9 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:37:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5550222
            Orig. end                         :: 5575381
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP042266.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25159
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="22"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25159
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25159
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15159](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15159
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(218..1567)
                     /locus_tag="FQU76_RS24315"
                     /old_locus_tag="FQU76_24315"
     CDS             complement(218..1567)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963667.1"
                     /locus_tag="FQU76_RS24315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24315"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_146482427.1"
                     /transl_table=11
                     /translation="MSRLALRMMTAALGALTLVTGCSDGGGGGGDGSGEGRRPDGARVT
                     IRVPGDAPTISDAVSLARPGDLVLVAPGVYRESVRINTERITLRGESRAGVVIDGQVRR
                     PNGVVVTAPGVAVENLTVRNNTHNGVLVTGSAAAVTGLPGSGGYDTGDEPVRLLKSFSV
                     SHVTATRNGLYGIYAFSAQNGVIERSYTSGGADSGIYVGQCRPCRIVVRDNVSELNAVG
                     YEGTNAGGDMYVVGNRLVGNRVGLTTNSDHQEKLLPQRDAVFAGNLIADNQQRQTPVQA
                     DGGWGIGIGVDGGSDNRFIRNRVTGNTNAGLVITATADLTADRNRITDNTFTANGIDVG
                     WTFPTATRGQGNCLERNVLRTTVPAGLASIASCPVAATSPTPSGGWRGPAAPAGIPFTE
                     VATPGPQPEFPGVGTVGATAVPDVPALPVIAEIALPSPSLLADGARVRTS"
     misc_feature    complement(1556..1558)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            1671..2819
                     /locus_tag="FQU76_RS24320"
                     /old_locus_tag="FQU76_24320"
     CDS             1671..2819
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669520.1"
                     /locus_tag="FQU76_RS24320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24320"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_146482428.1"
                     /transl_table=11
                     /translation="MHRADHPPSRRAFLDVTGATVAAGLLAGCSGDSARPAPSASPTSA
                     PVPGTGRHQSGVTLPRTAQPHLLALVADLGSSVAPGPLLAELGEAVRTLGAGSDPRLLG
                     LSPGDMTVTIGVGPRLVRAAGAALPGAADLPRFSRERVAPPSRGGDLLIQICAGDALLL
                     PAAAAALLDQAGDRVRERWRQFGRRGSEVPVAEGRSAPRNLLGFIDGIVGPHTTAEQER
                     DLWLAGPPAVAGGTLAVLRRMEFDLTRFAALSVAEQEAVFGRRRASGVPLSGGSVASAP
                     GLGAKTPDGRYLVPVDAHVRRANPTVVGVGHMLRRSYSIDHPSPGLLFISFQNDLRTFT
                     ATLSRMDSSDALLPFTTTTASATFLILPGYGPRRPLGSSLFG"
     gene            complement(3132..3785)
                     /locus_tag="FQU76_RS34850"
     CDS             complement(3132..3785)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS34850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_246150629.1"
                     /transl_table=11
                     /translation="MDDQRLLRNPLKIHKSVKAPRAKEKKAKASARTTVDTVREQLQER
                     YRFAVYLGLGLGLHQGEAFGLAEEDFDFTNMVVRIRRQLRWDTTRCPYFCLPKGGKTRE
                     VPLSPNLAARARAHFRRFPSTARTRPWRNPEPPTNALEKRQRRPITVRLVLTASHGNRI
                     YYKTWNERSWRPALAAVGLFTVLGEKVQRYGGQARRYPVYASSRADTFHVLRHT"
     gene            4371..5594
                     /gene="fxlM"
                     /locus_tag="FQU76_RS24335"
                     /old_locus_tag="FQU76_24335"
     CDS             4371..5594
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955816.1"
                     /locus_tag="FQU76_RS24335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24335"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_146482429.1"
                     /sec_met_domain="PCMT (E-value: 8.2e-35, bitscore: 119.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTTVDSDEAARLRNEVVDRLVADGAISSPEVEAVMRKVPRHAF
                     APEASLEKAYAPYAAVITKTDAHGVQLSSVSAPQIQAMMLGQARVRPGMRVLEIGSGGL
                     NAAYLAELVGEAGDVVTVDIDSTVTDRARRLLDEHGFGRVRVVCVDAAEPLDDLGTFDL
                     VMVTAGAWDIPPAWTGRLTPGGRLVVPLRMRGLTRSVAFVRVDDHLESESAFVCGFVPM
                     QGSTAHREELLLVAGTPEIGLRFDDGLPADPSLLDNAVTTPRVELWTGVEVGRGELVDT
                     LQMHLAITLPGFCVMTVDPDLDSGIVAPSNESFSLAAVDGADFAYLTVRRTEDDKGVEY
                     GVHALGPTASGFAKIVADHVRDWARDRRGGPNPVIRVHPAGTPDAQIPADRVIDKVHSR
                     ISLAWSPA"
     gene            complement(5805..6035)
                     /locus_tag="FQU76_RS24340"
                     /old_locus_tag="FQU76_24340"
     CDS             complement(5805..6035)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="FQU76_RS24340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24340"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_146482430.1"
                     /transl_table=11
                     /translation="MTTNLPPRVTATDLVPETAWFKSSYSSQDNGNCIEVADLGLRIGV
                     RDSKQKGGAALVVAPSAWSAFVSLAASEKIR"
     gene            complement(6032..6895)
                     /locus_tag="FQU76_RS24345"
                     /old_locus_tag="FQU76_24345"
     CDS             complement(6032..6895)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="FQU76_RS24345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24345"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_186768165.1"
                     /transl_table=11
                     /translation="MAARRGPTYLRVALGKELRALRDQLGLTAEAVSVELGFSRSKISR
                     VESGDIPLPKLIDLERILDRYGVHDIDARDALLQMQRGSLSKEPFTSYTSLLPSGLPMY
                     LGLERDATRIRGYENHVVHGLLQDETYATALARSAKVVEERTTAFVEQGVRLRMERKQL
                     LTQPDGPEVHIILTENALRTVIGSPEVMRAQYAELKRLCALERVEVQIIPEDLATYRSG
                     WNFTVLEFTGLGPVTQSDSAKATTMWSKESDVGQFQRQFDAMAMAAPGPAQTPQILDDL
                     EKRLWK"
     misc_feature    complement(6955..6973)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            7877..8383
                     /locus_tag="FQU76_RS24350"
                     /old_locus_tag="FQU76_24350"
     CDS             7877..8383
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960872.1"
                     /locus_tag="FQU76_RS24350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24350"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_146484565.1"
                     /transl_table=11
                     /translation="MENVTPPARDDDRKTRVAAGVILQNGRLLLIKRATPEGSLTWQFP
                     AGKIEPDESPEDAVIREVKQETGLVVTVTERLRERIHPGTGIRILYFACSILSGTAHRA
                     APDEVADITWVPLRDLSHYIPDGFFLPVQQYLDTTASHPERPAAPGGSAPGKGPVRGGH
                     PGESR"
     gene            8432..9655
                     /gene="fxlM"
                     /locus_tag="FQU76_RS24355"
                     /old_locus_tag="FQU76_24355"
     CDS             8432..9655
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953648.1"
                     /locus_tag="FQU76_RS24355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24355"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_146482432.1"
                     /sec_met_domain="PCMT (E-value: 3.8e-42, bitscore: 143.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVRDKNIDEEAASLRAAMVRELRDLEAITADSVAGAVAAVPRH
                     LFAVGEPLKAAYAANQALVIKRDEDGTALSSLSATHIQAVMLEQAGIEPGMRVLEVGSG
                     GYNAALIAELVGKEGASISVDIDAEIVERARKCLDAAGYEQVQVVRADAVAGVPELAPF
                     DRIIVTAGAWDIPSAWLDQLSERGRIVVPLRMRGLTRSIAFDRAGGGSEEELVSDSYRL
                     CGFVPMQGAGAYTERLIHVTDGLALRVDDQKQDFDTDALAAAVRSARLEVWSGAAFDLP
                     DELELFLATNTPEMVMLHGSKDLVDQGLLALSVTRGVPALVSGGSFAYRTKRANEETGG
                     FESGVLAHGPDAEQVAARYAELLRRWASDHQRRGAARISYRPMPAGTAEPSQGVVAKRL
                     GAVAFSWS"
     gene            9728..9922
                     /locus_tag="FQU76_RS24360"
                     /old_locus_tag="FQU76_24360"
     CDS             9728..9922
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345935.1"
                     /locus_tag="FQU76_RS24360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24360"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_146482433.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.6e-16, bitscore:
                     58.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQQIEDAAIAPHPQSAGEEESFENWDLDVSIVESGPSADRLIR
                     MTDDGCGVTCESACSTTCP"
     CDS_motif       9728..9850
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSAQQIEDAAIAPHPQSAGEEESFENWDLDVSIVESGPSAD"
                     /locus_tag="FQU76_RS24360_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9851..9922
                     /prepeptide="core"
                     /locus_tag="FQU76_RS24360_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-1.90"
                     /molecular_weight="2311.6"
                     /monoisotopic_mass="2310.0"
                     /core_sequence="RLIRMTDDGCGVTCESACSTTCP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSAQQIEDAAIAPHPQSAGEEESFENWDLDVSIVESGPSAD
                     "
                     /leader_location="[9727:9850](+)"
                     /alternative_weights="2329.7"
                     /alternative_weights="2347.7"
     gene            10001..13051
                     /locus_tag="FQU76_RS24365"
                     /old_locus_tag="FQU76_24365"
     CDS             10001..13051
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960873.1"
                     /locus_tag="FQU76_RS24365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24365"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_146482434.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.3e-190,
                     bitscore: 632.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.1e-17,
                     bitscore: 61.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.3e-26, bitscore:
                     90.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAHVDAALLRAGAWAPDDLVQPWPDPGGDADSWRAWLERTLRIP
                     GFAEALEQASPALARRVRDIRDEQNLPERAVRKATFAVLRYLLRASNRATPFGFFAGVA
                     PVRLADAATVRIGSGHRAVVRVDAVWLTTVIERLEADRALLPHLMVQTHALVAEKDGHL
                     VLDHRGTGSSGGAPARVQVRVTPPVTSALAAARHPIRVADLVAKLAGDFPRVPSEVIAK
                     LLADLIAQHLLVTNLRAPMTTMNPLNHLLSALDAAEAENLQSAGATVARLRSFTHALAR
                     PHTSPEYGEHRAQFNAEMRHIAPGTAPVLGTDLRIDGEATVPTAVADEAARAATALVRL
                     ARQPFLSRAWANWHGRFLERYGPRALIPVLDAVDGDTGLGYPAGFLGGPPAPASAPLTE
                     RDGKLLALAQNAALRRQYEIVVDDAMINALTVIGPDTGVQPTTELIARINAASTDALGD
                     GEFTLAVTGVSRTAGTVTGRFLHLLDAHDRNRMATAYATAATATDDALPVQISAPPLHT
                     STENVARAPAVMPAVLAWGECHDHIGERVLLDDITVTADVHRLYLVSRSRRRPLEFVNL
                     NAVEPVHRTHPLVRFLAEATHAMSAPCAVFDWGTATTLPFLPAVRYGRTILSPARWLLT
                     TADLAARETDQPQWDESLVAWREQVAIPSTVYAGDGDQRLRLNLDEPVHRMLLRAQVQR
                     SGTAVLRAEAAPDAGWIGERPHELVIPLARTGRGRRAPWWLDRETGTPDGHGHVPGCDG
                     RFLVQLYARPERHGGILRRLPELLAELGGRTQWWFLPYRDPDDHLRLRLVVPADHAEGA
                     PAAIGGWTRALRRAGLTSRVRWDTDFPETARFGGPAAIDAAETFFAADSEAAAAQLAFS
                     TANSGPDAQAVTAASMIDLTTGLIGNPADAMAWLIDHARTTSTAPARDVYAQAVALGNP
                     YDHDALTRQPGGQRITAAWARRRETLADYRAVLDTAGTADVNVLLPELLHLHHTRVAGI
                     DLDAEGQCLHLARAAALSWTARGRTRS"
     aSDomain        10469..10720
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FQU76_RS24365_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.70E-19"
                     /identifier="RREFam001.1"
                     /label="FQU76_RS24365"
                     /locus_tag="FQU76_RS24365"
                     /protein_end="240"
                     /protein_start="156"
                     /score="61.3"
                     /tool="antismash"
                     /translation="AEKDGHLVLDHRGTGSSGGAPARVQVRVTPPVTSALAAARHPIRV
                     ADLVAKLAGDFPRVPSEVIAKLLADLIAQHLLVTNLRAP"
     gene            13048..14280
                     /locus_tag="FQU76_RS24370"
                     /old_locus_tag="FQU76_24370"
     CDS             13048..14280
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953651.1"
                     /locus_tag="FQU76_RS24370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24370"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_146482435.1"
                     /sec_met_domain="LANC_like (E-value: 2.1e-37, bitscore:
                     127.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRIPKALAVADGLAAELADPRSASPEAGGGRAWPQSLAGGAAGI
                     ALLHVVRARAGRGDWGTACTWISRAASDDLAAASNAGLYLGAPALAFVLHTAAGSTGRY
                     RNALEKLDDATISITRRRLAEAHARIDDGERPAMKEFDLIRGLTGFAAHHLARHPDHEI
                     TADTLAYLVRLTEPLLDGDDALPSWWTDVSPSGEPTPDFPGGHGNFGLAHGIGATLSVL
                     SLALMRGADAPGLADAAGRICAWTDRWRQGDDTEPWWPGFITAGQAAGGRIESALRPRP
                     SWCYGVAGTARAQQLAGLALGEPARVRAAENAMLAALRDPAQLDQVPEIGLCHGTAGLL
                     HAAWRMADQTGNPAIAAELPQMTDRLTAALNRSDRDPELLDGTAGAALVLHTVGTGTVA
                     APYWDTFLALA"
     gene            14296..15159
                     /locus_tag="FQU76_RS24375"
                     /old_locus_tag="FQU76_24375"
     CDS             14296..15159
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006345938.1"
                     /locus_tag="FQU76_RS24375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24375"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_146482436.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.7e-37, bitscore:
                     126.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSPTWQQVNISFPDWTRAEHTALKHLAPILFAAEDNGEITAWFH
                     ISKRPCWRLRYLPSTDTDSQIGRELDALTTAGRITGWTPIVYEPEIHAFGGTEAMETAH
                     HFFHHDSRGLLTYLRDGDQDAGGHRREISLLLCSILMRTAGLDWYEQGDVWARVAAHRP
                     LPVGRRSTARQRAAVHRLLTVDTNDQTSENGPLARTREWARAYTTAGQELGNLTTTGAL
                     HRGLRDVLAHHVIFAWNRLGLPYATQAALAATAKDIVFGPDPAIYGDAAATSTDTGVSN
                     PVQPRR"
     gene            15191..16297
                     /locus_tag="FQU76_RS24380"
                     /old_locus_tag="FQU76_24380"
     CDS             15191..16297
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006347623.1"
                     /locus_tag="FQU76_RS24380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24380"
                     /product="hypothetical protein"
                     /protein_id="WP_146482437.1"
                     /transl_table=11
                     /translation="MHPNDPIAQRFPLVARPRPACLPLTERIHALLDLARTAAEENDPA
                     RASAVYNQSALLASDLGLPTLARDLCHRHADAYLHARPLTGQRAIQALEPVVNFARLHI
                     RAGNGDAARQHLLALYEAVSRGTAVQLDSIAVPAHLTATTEDCREVRTWLWTVLLADGT
                     RALTAQGRWNDALTHIQKHRGMGERMLDGRQVAVLAALTAGDPVPAAALLHATTPGEPW
                     EQVVTACLTALCHRVAQRTADLNVESLVGMYERLEPKPGTAVFSSRLGLTILDVIGADT
                     ATARRVANELHHRATKQNDGYASLENLRHPLFNALATEGQQRDCREILDACALGAGELP
                     DELRELLMAAAGTSDRTIRRTILVRQRR"
     misc_feature    15281..15283
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15887..15889
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16217..16219
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16504..17871)
                     /locus_tag="FQU76_RS24385"
                     /old_locus_tag="FQU76_24385"
     CDS             complement(16504..17871)
                     /EC_number="4.3.1.17"
                     /GO_function="GO:0003941 - L-serine ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009063 - amino acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889625.1"
                     /locus_tag="FQU76_RS24385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24385"
                     /product="L-serine ammonia-lyase"
                     /protein_id="WP_146482438.1"
                     /transl_table=11
                     /translation="MAISVFDLFSIGIGPSSSHTVGPMRAARMFARRLKNEGLLAHTAA
                     VRAELYGSLGATGHGHGTPMAVLLGLAGNSPRTVDVETADEQVAQIKESGRISLLGAHE
                     IAFDFDEDLVLHRRKALPYHANGMTIRAYDADGGTVLEKTYYSVGGGFVVDEDAVGEDR
                     IKLDDTVLKYPFRTGDELLRLARDTGLSISSLMLENEKAWRTEEEIRTGLLEIWQVMQA
                     CVARGLSREGILPGGLKVRRRAANTARQLRAEGDPAALAMEWITLYAMAVNEENAAGGR
                     VVTAPTNGAAGIIPAVLHHYMNFVPGADEDGIVRFLLAAGAIGMLFKENASISGAEVGC
                     QGEVGSACSMAAGALAEVLGGTAAQVENAAEIGMEHNLGLTCDPVGGLVQIPCIERNGM
                     AAVKAVTAAKMAMRGDGSHLVSLDKVIKTMKETGADMSVKYKETARGGLAVNIIEC"
     gene            complement(18057..19319)
                     /gene="glyA"
                     /locus_tag="FQU76_RS24390"
                     /old_locus_tag="FQU76_24390"
     CDS             complement(18057..19319)
                     /EC_number="2.1.2.1"
                     /GO_function="GO:0004372 - glycine hydroxymethyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070905 - serine binding [Evidence IEA]"
                     /GO_process="GO:0019264 - glycine biosynthetic process from
                     serine [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (75-369). E-value:
                     3.7e-13. Score: 41.2. Matches aSDomain:
                     nrpspksdomains_FQU76_RS24390_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="glyA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004949858.1"
                     /locus_tag="FQU76_RS24390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24390"
                     /product="serine hydroxymethyltransferase"
                     /protein_id="WP_146482439.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.8e-11, bitscore:
                     41.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLNTPLHELDPDVAAAVDAELHRQQSTLEMIASENFAPVAVME
                     AQGSVLTNKYAEGYPGRRYYGGCEHVDVVEQIAIDRVKALFGAEHANVQPHSGAQANAA
                     AMFALLKPGDTIMGLNLAHGGHLTHGMKINFSGKLYNVVAYHVDDATGRVDMAEVEKLA
                     KESRPKLIVAGWSAYPRQLDFAAFRRIADEVGAYLMVDMAHFAGLVAAGLHPNPVPHAH
                     VVTTTTHKTLGGPRGGVILSTAELAKKINSAVFPGQQGGPLEHVVAAKAVSFKVAASEE
                     FKDRQQRTLEGAKILAERLVREDVAEHGVSVLSGGTDVHLVLVDLRHSELDGQQAEDRL
                     HEVGITVNRNAIPNDPRPPMVTSGLRIGTPALATRGFGADDFREVADIIAETLKPGYDT
                     EALRGRVTALADKHPLYPGLK"
     aSDomain        complement(18213..19094)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FQU76_RS24390_Aminotran_1_2.1"
                     /evalue="3.70E-13"
                     /label="FQU76_RS24390_Aminotran_1_2.1"
                     /locus_tag="FQU76_RS24390"
                     /protein_end="369"
                     /protein_start="75"
                     /score="41.2"
                     /tool="antismash"
                     /translation="QIAIDRVKALFGAEHANVQPHSGAQANAAAMFALLKPGDTIMGLN
                     LAHGGHLTHGMKINFSGKLYNVVAYHVDDATGRVDMAEVEKLAKESRPKLIVAGWSAYP
                     RQLDFAAFRRIADEVGAYLMVDMAHFAGLVAAGLHPNPVPHAHVVTTTTHKTLGGPRGG
                     VILSTAELAKKINSAVFPGQQGGPLEHVVAAKAVSFKVAASEEFKDRQQRTLEGAKILA
                     ERLVREDVAEHGVSVLSGGTDVHLVLVDLRHSELDGQQAEDRLHEVGITVNRNAIPNDP
                     RPPMVTSGLRIGT"
     gene            complement(19340..19717)
                     /gene="gcvH"
                     /locus_tag="FQU76_RS24395"
                     /old_locus_tag="FQU76_24395"
     CDS             complement(19340..19717)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /gene="gcvH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010984206.1"
                     /locus_tag="FQU76_RS24395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24395"
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="WP_006346430.1"
                     /transl_table=11
                     /translation="MSNPQQLRYSKEHEWLTAAEDGVSTVGITEFAANALGDVVFAQLP
                     EVGAQVSAGESCGELESTKSVSDLYSPVSGEVTEINQDVVDDPSLVNSAPFEGGWLFKV
                     RVAEEPDDLLSADEYAEFTKS"
     gene            complement(19842..20957)
                     /gene="gcvT"
                     /locus_tag="FQU76_RS24400"
                     /old_locus_tag="FQU76_24400"
     CDS             complement(19842..20957)
                     /EC_number="2.1.2.10"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004047 - aminomethyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /codon_start=1
                     /gene="gcvT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018509776.1"
                     /locus_tag="FQU76_RS24400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24400"
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="WP_146482440.1"
                     /transl_table=11
                     /translation="MSTAPRRTALDALHRSLGATMTDFAGWDMPLRYASEREEHQAVRT
                     RAGLFDLSHMGEITVSGPQAAALLDHALVGNISTIGPGRARYTMICREDGGILDDLIVY
                     RTGATEYLVVANAGNAQTVLDAVTERAAGFDAEVRDDRDAYALIAVQGPEAPGILKSVT
                     DADLDGLKYYAGLPGTVAGVPALIARTGYTGEDGFELFVAPEHAEGLWRALTEAGAAVG
                     LVPCGLSCRDTLRLEAGMPLYGHELTTALTPFDAGLGRVVKFEKEGDFVGRKALEAAAE
                     RAASAPPRTLVGLIAEGRRVPRAGYPVVADGAVIGEVTSGAPSPTLGKPIAMAYVDAAH
                     AAPGTAGVGVDIRGAHEPYEVVALPFYRRQK"
     regulatory      complement(21132..21226)
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(21559..21573)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.04"
                     /tool="antismash"
     gene            21662..22477
                     /locus_tag="FQU76_RS24405"
                     /old_locus_tag="FQU76_24405"
     CDS             21662..22477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946792.1"
                     /locus_tag="FQU76_RS24405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24405"
                     /product="AAA family ATPase"
                     /protein_id="WP_146482441.1"
                     /transl_table=11
                     /translation="MTLQRSSAYATTAGVPAQPGAPVRERVGAHAPPVLRDLRGRAGRG
                     PRALTFAAGDLVVVSGLPGSGKSTLIKRAVAAAGARPAAGSAPEAVSAAVSGPGPESGS
                     AAPEGAGPEAGPGAAGDPGSVCGIDSQDTRDRWDAAVPRLLPYALYRPFVRLAHYAGLR
                     RALRSGRSVVVHDCGTQAWVRRWLAREARRRGTGLHLMLLDVPPEVARQGQEQRGRGVS
                     GYAFARHRRAAGRLIADAEAGRAPAGCASVILLDRPAATALARIGFTAG"
     gene            22580..23395
                     /locus_tag="FQU76_RS24410"
                     /old_locus_tag="FQU76_24410"
     CDS             22580..23395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346427.1"
                     /locus_tag="FQU76_RS24410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24410"
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="WP_146482442.1"
                     /transl_table=11
                     /translation="MNVAEQPDSRSYGGAHGGPYAAWPVNELEETLAASLGNPDAGARL
                     VEVLGRSRIWVPLPNGGGPDSVRLDLPMVEIGGAAYVPVFSSEEQYRACVGDGLPYTVA
                     PARDFARGLPPQVGIVVNPDGTVGVPLPPPAVAELCRAGRGPLDGPASGGRVRLFEPDW
                     QDDPVDFLAAASVEFGATGVVATARRGLASVEGDDPALFIGVQLFPAGTPETALDALGR
                     ALGRCAVRWPVNLVFLDLTEDPVADWFRTSVRPFFEGELRLRGGAGIRP"
     gene            23575..24360
                     /locus_tag="FQU76_RS24415"
                     /old_locus_tag="FQU76_24415"
     CDS             23575..24360
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946790.1"
                     /locus_tag="FQU76_RS24415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_24415"
                     /product="enhanced serine sensitivity protein SseB
                     C-terminal domain-containing protein"
                     /protein_id="WP_146482443.1"
                     /transl_table=11
                     /translation="MSASGTAAAGQIEHMLRQVTPGRYDAYEALLAALAEPAGGRVWML
                     LWNGRPGTPDAQYGNLEVDGHGYAPAVTSAQELSASSWSRAHEVVSGLDIARALYPDRW
                     GIWLNPHAPGGGVGIPWTDLRRIATGLDRMPAGPLRLSEPAIDIPQFYALLARNAHQTP
                     AVRSLRRAWVQPALGAPYLAIGLDLYDTSRPSVDAVRAMMQQSIAAVPDGLPVSTVALS
                     DEYDPVGMWLLAHARPFYDREAHAAPGAGGYGYPPAAGR"
     misc_feature    24621..24635
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.09"
                     /tool="antismash"
     misc_feature    complement(24796..24815)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 25.05"
                     /tool="antismash"
     misc_feature    24828..24841
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.0"
                     /tool="antismash"
     misc_feature    complement(24828..24841)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 22.97"
                     /tool="antismash"
     misc_feature    24867..24880
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.3"
                     /tool="antismash"
     misc_feature    25145..25159
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 gccgaagccg gtcccggtgc ccatggcaag gccgacaccg gctccaacac cagtacgtca
       61 cagaccgtcc gctactggat cggctcggac ggcaccatgt accgggtcga gatcgctgtc
      121 gcctccgcgc cgcggccggt ggtcctggac ttcgacaccc agacgtacgt cccggtcaag
      181 ccgctgcccg gagccacccc gacgccgtag ccgccgctca tgaggtccgc acccgcgcgc
      241 cgtcggcgag cagcgacggc gacggcagcg cgatctccgc gatgaccggt agcgccggta
      301 cgtccggcac agcggtggcg ccgaccgtgc cgacccccgg gaactcgggc tgggggccgg
      361 gcgtggccac ctccgtgaag gggatgcccg cgggcgccgc cgggccccgc cagccgccgg
      421 agggcgtggg tgacgtggcg gcgaccgggc aggacgcgat cgacgcgagc cccgcgggca
      481 cagtcgttcg aaggacgttc ctttccaggc agttgccctg cccccgggtg gcggtgggga
      541 acgtccagcc gacgtcgatg ccgttggcgg tgaaggtgtt gtccgtgatc cggttgcggt
      601 ccgccgtcag atcggcggtc gcggtgatca cgagcccggc gttggtgttg ccggtgaccc
      661 ggttgcggat gaaccggttg tcgctgccgc cgtcgacgcc gatgccgatg ccccagccgc
      721 cgtcggcctg tacgggggtc tgccgctgct ggttgtccgc gatcaggttg cccgcgaaga
      781 cggcgtcgcg ctgcgggagc agcttctcct gatggtcgga gttggtggtc agcccgaccc
      841 ggttgccgac cagacggttg ccgaccacat acatgtcacc gcccgcgttg gtgccctcgt
      901 aaccgaccgc gttgagttcg gagacgttgt cccgcaccac gatccggcat ggtctgcact
      961 ggccgacgta gatacccgag tcggccccgc ccgaggtgta cgagcgttcg atgaccccgt
     1021 tctgcgcgga gaacgcgtag atgccgtaga ggccgttacg ggtcgccgtc acatgcgata
     1081 ccgagaacga cttcaggagg cggacgggtt cgtcgccggt gtcgtagccg ccactccccg
     1141 gcagcccggt gaccgccgcc gcggaaccgg tgaccagtac tccgttgtgc gtgttgttcc
     1201 gcacggtcag gttctccacg gccaccccgg gcgccgtgac gaccacaccg ttcggccgcc
     1261 gcacctgccc gtcgatgacc accccggccc gggactcgcc ccgcagagtg atgcgctccg
     1321 tgttgatccg taccgactcg cggtagacac ccggagccac gaggaccagg tcaccaggcc
     1381 gggccaggga caccgcatcc gagatggtcg gggcgtcgcc gggcacccgg atcgtgaccc
     1441 gcgcgccgtc cggccttcgg ccctcgcccg atccgtcgcc gcccccgccg ccaccgtcgc
     1501 tacagccggt caccagtgtc agtgcgccca gggcagccgt catcatgcga agagctaatc
     1561 gagacatgat cccagtctga cacggcgtca atccgctgga ttatcgaact ccggatccgg
     1621 gtaagggggt tgagcggcgg gagcggatcg ggtgtggcac tgtacgcatc atgcatcgcg
     1681 ccgatcaccc cccgtcgcgc cgcgcgttcc tcgatgtcac cggcgccacg gtggccgccg
     1741 gtctcctcgc cgggtgctcg ggggactccg cccggcccgc cccttccgcg tcgcccacgt
     1801 ccgcgccggt cccggggacg ggacggcatc agtcgggcgt gacgcttccc cggacggccc
     1861 agccccacct gctggccctg gtggccgacc tcggctcctc ggtggcgccc ggcccgttgc
     1921 tggccgaact cggcgaggcc gtccgcactc tcggcgccgg gtccgacccg cggctcctgg
     1981 gactgtcccc gggcgatatg accgtgacca tcggcgtggg tccacggctg gtacgggcgg
     2041 ccggcgccgc gctgcccggc gcggccgacc tgccgcggtt ctcccgcgag cgggtggccc
     2101 cgccgtcgcg cggcggtgat ctgctgatac agatctgcgc cggcgacgcc ctgctcctac
     2161 cggccgccgc cgccgcgctc ctggaccagg ccggcgaccg tgtccgggag cgctggcggc
     2221 agttcggacg ccgcggttcc gaggtacccg tggccgaggg ccgctccgca ccgcgcaacc
     2281 tgctcggttt catcgacggc atcgtgggcc cgcacaccac cgccgaacag gaacgtgacc
     2341 tgtggctggc cggacccccc gcggtcgccg gcggcaccct ggccgtacta cggcgcatgg
     2401 aattcgacct gacgcggttc gccgcgctgt cggtcgccga gcaggaggcg gtcttcggac
     2461 ggcgccgggc cagtggcgta cccctctccg gcggcagcgt cgcctcggcc cccggactcg
     2521 gcgccaagac gcccgacggg cgctacctcg tacccgtgga cgcccatgtg cgcagggcga
     2581 atcccaccgt ggtcggcgtc ggccatatgc tccgccgttc ctacagcatc gaccatccct
     2641 cgcccggcct gctcttcatc agcttccaga acgacctgcg gaccttcacg gccacgctca
     2701 gccgtatgga ctcctccgac gcgctgctgc ccttcaccac gacgaccgcc agcgcgacct
     2761 tcctgatcct ccccggctac ggcccgcgtc gcccgctcgg ttcctcattg ttcggctgat
     2821 ccgtgaacgc cgcatagggc ctccgtggat aggttccctg ggactttcac accggccgca
     2881 gttgccggtc caggaacttc cgccgtgcaa cagggaaagg ccctgaccgc gccgaaagat
     2941 ggaaaaagcg ctgctcaggg cctacgggcc aaggggctcg gcgctcgatg acgttcaccg
     3001 cgagcccgcc ccgcgccatc tccttgtact tcaccttcat tgttgccatc gagcgtgatc
     3061 ttgagggagg agtgcccgag caaggccgcg aggctcacca cggacttgcc ggcctccagc
     3121 tgcacactgg cttaggtgtg ccgcaggaca tggaacgtgt ccgcccgcga cgacgcatag
     3181 accgggtagc ggcgggcctg gccgccgtac cgctggacct tctccccgag cacggtgaac
     3241 agcccgacgg ccgcgagggc gggccgccag ctccgctcgt tccacgtctt gtagtagatc
     3301 cggttcccgt gggaggcggt gaggacgagc cgcacggtga tcggacgccg ctgccgcttc
     3361 tccagagcgt tggtcggagg ctccgggttc cgccagggac gggtgcgcgc cgtcgaaggg
     3421 aaccggcgga agtgcgcgcg ggcgcgagcc gccaggttgg gggagagcgg cacctcccgc
     3481 gtcttgccgc ccttaggtag acagaagtac ggacacctcg tcgtgtccca ccggagctga
     3541 cgccggatgc gcacgaccat gttcgtgaag tcgaagtcct cctcggccag gccgaacgcc
     3601 tctccttggt gaagcccgag gccgagcccc aggtacacgg cgaaccggta gcgctcctgg
     3661 agctgctccc gcacggtgtc gacggtggta cgggccgacg ccttggcttt cttctccttg
     3721 gcacgcggag ccttgacgct cttgtggatt ttaagcgggt tccgcagaag ccgctgatcg
     3781 tccacttgcg gtgcggtgat tccttccgag cgggtgttca gaacgccggc tgcagccggt
     3841 ccttatcgac ggtccctgcc gtcgttgacg ccagacgtac agggtgtctg ggggagaggc
     3901 ccagataggt ggctgcttgg ggaaggctca agaaggccgt ttcgtgctgt gaggttacct
     3961 ggggcgtagc tgcgttcctg tcgtccggcc ttgaggtgac aggaggatga tccggagaaa
     4021 gggaggcttg gttgagccgg gccgttagtg ataggggcct tggtcgactt cttgatatgt
     4081 gacccttctg catggcttca ggtcggatca gccacagaat ccgagaggga ttgatcaggt
     4141 cggcgatgac ctggtcagca cctacgttgg ccaggttgtc ctgagtcagg tcgtgcggta
     4201 atgacccaca ggaggctgag taaccgctgc agcgtattcc ggccagccct cgtcgtttgc
     4261 cggggaagag tggcgcccgc cgatagcgtt ccggcgtgct cgcaccgacc gacggcgccc
     4321 cgccggcagg ttcttcccgc cctgaacatg tacgaatgaa ggacaccctc atgacccaca
     4381 cgacggtcga ctccgacgag gccgcacggc tccgcaacga ggtcgtggac cggttggtcg
     4441 cggacggcgc gatctcctcc ccggaggtcg aggctgtgat gcggaaggtc ccccggcacg
     4501 cgttcgcccc cgaggcgagt ctggagaagg catacgcccc gtacgcggcc gtcatcacca
     4561 agacggacgc gcacggcgtc cagctcagct cggtctccgc gccgcagatc caggcgatga
     4621 tgctggggca ggcccgggtc cgacccggga tgagggtgct ggagatcggc tcgggcggtc
     4681 tgaacgcggc ttacctcgcc gagttggtcg gggaagccgg tgacgtggtc accgtggaca
     4741 tcgactccac cgtcacggac cgggcccgcc ggctgctgga cgagcacggc ttcggccggg
     4801 tccgagtggt ctgcgtcgac gcggcggagc ccctcgacga cctcggtacg ttcgacctcg
     4861 tcatggtgac cgctggcgcg tgggacatcc cgcccgcgtg gaccgggcgg ctcacccccg
     4921 gcgggcgtct ggtggtaccg ctgcggatgc gcgggctcac ccggtccgtg gccttcgtcc
     4981 gcgtcgacga tcacctggag agcgagtccg cgttcgtctg cggcttcgtc cccatgcagg
     5041 gctcgaccgc gcaccgggag gaactgctgc tcgtcgccgg gactccggag atcgggctgc
     5101 ggttcgatga cggactgcca gccgacccga gcctgctcga caacgccgtc accacgcccc
     5161 gggtggagct gtggaccggg gttgaggtcg gtcgcggcga actcgtcgac acgctccaga
     5221 tgcacctggc gatcacactg cccggcttct gcgtcatgac ggtcgacccc gacttggaca
     5281 gcgggatcgt cgccccctcg aacgagtcct tctccctggc ggccgtggac ggcgccgact
     5341 tcgcctatct caccgtccgc cggaccgagg atgacaaggg cgtcgagtac ggcgtccacg
     5401 ccctcggccc cacggcctcc ggtttcgcca agatcgtcgc ggaccacgtc cgtgactggg
     5461 cccgcgaccg gcgcggcggc cccaatccgg tcatccgcgt ccatccggcc ggcacccccg
     5521 acgcgcagat cccggccgac cgagtcatcg acaaggtgca cagccggatc tcgctcgcct
     5581 ggtctccggc gtagctgtcg gagatcaggt tcccgtacta ctctggaaga gagggtcacg
     5641 agaccagcct tcgggccgac gtctaacccg ttccctcagg gcacgctgct gagatggata
     5701 cgggcagatc ggtatttgat cgactgggat agtcgtgaag cgtgatgctc cgagtgtcgg
     5761 gaagggacgg gtgcctcggc catgccgagg tacccgtccg cgaatcacct gatcttttcc
     5821 gaggcagcga ggcttacgaa agcactccag gccgaaggcg caaccaccag cgcggccccg
     5881 cccttctgct tcgagtcccg gacaccgatt cggagtccga gatctgcgac ctctatgcag
     5941 ttgccgttgt cctgggagct gtaagaggac ttgaaccagg ccgtctccgg aacgaggtcg
     6001 gtagcggtta cgcgcggggg aagatttgtc gtcatttcca cagtctcttt tcgaggtcat
     6061 ccaggatttg aggggtctgc gccggccccg gtgccgccat ggccatcgca tcgaactgtc
     6121 gctggaactg ccccacgtcc gactccttcg accacatggt ggtggccttg gcgctgtcgc
     6181 tctgagtcac aggcccgagg cccgtgaact ccagcaccgt gaagttccag ccggagcggt
     6241 aggtggcaag gtcttccggg atgatctgca cctccaccct ctctagggcg cagagccgct
     6301 tcagctctgc gtactgcgct cgcatgacct ctggcgagcc gatgaccgta cgcagcgcgt
     6361 tctccgtcag gatgatgtgc acctccggcc cgtccggttg ggtcagaagc tgctttcgtt
     6421 ccatcctgag tcgcacgcct tgctcgacga acgccgtggt ccgttcctcg accaccttgg
     6481 cggaccgtgc gagcgctgtg gcataggtct cgtcctgcaa gagcccatgg acgacgtggt
     6541 tctcgtaccc gcggatacgg gtcgcgtccc gctccaaccc gagatacatc ggcaggccgg
     6601 agggcaggag gctggtgtag gaggtgaacg gctctttact cagggagccg cgctgcatct
     6661 gcaacaaggc atccctggcg tcgatgtcgt gcaccccgta cctgtcgagg atgcgttcga
     6721 ggtcaatcag cttcggtagg gggatgtccc cgctttcgac cctgctgatc ttcgagcggg
     6781 agaaccccag ctcgaccgag acggcctccg ctgtgagccc cagctgatcg cggagtgctc
     6841 gaagttcctt gccgagtgcg acccgcaggt acgtcggtcc tcgtcgtgcg gccactatcc
     6901 ctgtcccctc gtcctgatgg gctgtccgtc ggatcgaggc ccctgtccgg cagcacaggt
     6961 tatctgtcca ccatgccagg ggctcagtct gatcgctgac ctcgcccgct cttcgttcca
     7021 cacagccagt cggttaccag acatttgcca atgtgcgttc atgggagctt tctcttgaat
     7081 gttaactgga gtgtgcagca cgcttgttgg cctcagcagc ttccctgtgc acggccggga
     7141 cgacgcacct tccgtcgctg ctgacatccc tgtccagacc gcaggagggc tgcatggcaa
     7201 ccacagttgt gagtcctcag agcgctctgg gcgtccttgg atcaatcgcc gacccgcagc
     7261 ccgtcgtgct tgatgcccga cttcagcgag agcaggcatg gccccctcgc ccaacgatgg
     7321 aggaagtgct gcccgtcccc ggtcaaggca ccgactccgc cggtcctctt ctctccgctc
     7381 tcccacggga ggcaaacatg tccacgaccg ttcacagcct gcccgtacga gatgcggagg
     7441 ctgcccgctc ccaacctgtg gagcgtgccc gcccctcatc cgcgcaggag ctgttagggc
     7501 ttctcaacag cctcaacggt tcgttcatcc aagacggcgt agaagagtat ctggagcgga
     7561 ttctcgggtg gggagcgagc ccgcttacct ccaccgagcg cttgacgctc gtcggcaggc
     7621 tccgctcctg cctctggccg ctggtgaccg acgctctgca cggcgcgaag ggccgtccga
     7681 acgacttcct gcgccagctc gtcagcgcgg cgatccggct cgacgccgag ggcagtgcga
     7741 aggagttcgt gccgagtccc cttggtgatg tccgaccacc acatcgtccg gctcaccctc
     7801 gacggcgacc ggctcgcgga catcctcaac cggcagccgg tcggcgcccc ctccttcgcc
     7861 gagtgaggtg aaggccatgg agaacgtgac accgccagct cgcgacgacg accggaagac
     7921 cagggtcgcg gccggcgtga tcctccagaa cggacgtctc ctgctcatca aacgggcaac
     7981 acccgaaggg tcgctcacct ggcagttccc ggccggaaag atcgagccgg acgagtcacc
     8041 cgaagacgct gtcatacggg aggtgaagca ggagaccggc ctcgtcgtca ccgtcacgga
     8101 acgactgaga gaacggatcc acccgggcac cggcatccgc atcctctact tcgcctgctc
     8161 catcctgtcc ggcaccgccc accgcgcggc ccccgacgaa gtcgcggaca tcacctgggt
     8221 gccgctccgc gacctatccc actacatacc tgacgggttc tttcttcctg tccagcagta
     8281 cctcgacacc accgccagcc atccggaacg gcctgccgcg ccgggcggct cggcgcccgg
     8341 taaagggccg gttcggggcg gtcatccggg ggagtcgcgg tgattccggc aatgcagctg
     8401 gaccacgaaa cacgatcggt agggtgacga agtgactacg gtacgagaca agaacattga
     8461 tgaggaagcg gcctcgttgc gggcggccat ggtgcgtgag ctgcgcgatc tggaggccat
     8521 cacagctgac tccgtcgccg gtgcggtggc cgctgtgccc cggcatctgt tcgccgtcgg
     8581 cgagccgctg aaggccgcgt acgcagccaa ccaggccctg gtgatcaagc gggacgagga
     8641 cggtacggca ctcagctcgc tgtcggccac acacatccag gcggtgatgc tggagcaggc
     8701 cgggatcgag cccggcatgc gggtcctcga agtcggctcg ggtggctaca acgccgcgct
     8761 gatcgccgag ctggtcggca aggagggcgc gtcgatctcg gtggacatcg acgcggagat
     8821 cgtcgagcgc gcccggaagt gtctggacgc ggctggatac gagcaggttc aggtggtgcg
     8881 ggccgacgcc gtcgccgggg taccggagct ggctccgttc gaccggatca tcgtcaccgc
     8941 cggggcctgg gacatcccgt cggcgtggct ggaccagctc tccgagcgcg gccggatcgt
     9001 cgtccccctc cggatgcgcg ggctcacccg gtcgatcgcg ttcgaccggg ccggcggcgg
     9061 ctcggaagag gagctggtca gcgacagcta ccgcctgtgc ggcttcgtgc ccatgcaggg
     9121 agccggcgcg tacaccgagc ggctcatcca cgtcaccgat ggcctcgcgc tgcgcgtcga
     9181 tgaccagaag caggacttcg acaccgacgc cctggccgcc gccgtgcgct cggcccggct
     9241 ggaggtgtgg tccggggcgg cgttcgatct gccggacgag ttggaactgt tcctggcgac
     9301 gaacacgccg gagatggtga tgctccacgg cagcaaggac ttggtcgacc agggccttct
     9361 cgcgctgtcg gtgacgcgcg gcgtcccggc gctggtcagc ggtgggagct ttgcgtaccg
     9421 cacgaagcgg gcgaacgagg agaccggcgg cttcgagagc ggtgtcctcg cccacggtcc
     9481 cgacgccgaa caggtcgcgg cccgctacgc cgagctgctg cggcggtggg cgtcggacca
     9541 ccagcggcgc ggggccgccc ggatctcgta ccggccgatg cccgccggta cggctgaacc
     9601 gtcccagggg gttgtggcga agcggctcgg cgctgtcgct ttctcctggt cgtaggctcc
     9661 ccggcccccg cggcatcgtc acgggggcac ggggcattcg caccacccaa ctatcaggga
     9721 ggttgttgtg tccgcacagc agatcgaaga cgcggcgata gcgccacacc cgcagagcgc
     9781 gggcgaggag gagagcttcg agaattggga cctggacgtc tcgatcgtgg agtccggccc
     9841 gtcggccgac cggctcatcc ggatgactga cgacggctgc ggtgtgacct gcgagtccgc
     9901 ctgctcgacc acctgcccgt agcagatccg aaggactgaa ccgcggtgcc cggtcggctt
     9961 cggagggccg ggcaccgcgc tccacgaagg ggagttgccg gtgtacgcgc acgtcgatgc
    10021 cgcgctgctg cgggccgggg cctgggctcc ggacgatctc gtccagccgt ggcccgaccc
    10081 gggcggagac gcggactcct ggcgggcgtg gctggagcga acccttcgga tacccggctt
    10141 cgcggaagct ctggagcagg ccagccctgc gctggctcga cgcgttcggg acatccgcga
    10201 tgaacagaac ctgcccgaac gcgccgtacg aaaggcgacg ttcgccgtcc tgcggtatct
    10261 gctgcgggcg tcgaaccggg ccaccccgtt cggcttcttc gccggagtgg cacccgtgcg
    10321 cttggccgac gcggcgacgg tgcgcatcgg ctccgggcac cgggccgtcg tcagagtcga
    10381 cgcggtgtgg ctgaccacgg tgatcgagcg gctggaagcg gaccgagccc tgctgccgca
    10441 cctgatggtg cagacccatg cgctggtggc ggagaaggac ggtcacctgg tgctcgacca
    10501 ccggggcacc ggcagctcgg gcggcgcccc ggcccgggtt caggtccgtg tcaccccgcc
    10561 tgtcacctcg gccctggctg cggctcgcca tcccatccgg gtcgcggacc tcgtcgctaa
    10621 gctggccggc gactttcccc gcgtgccctc cgaggtgatc gccaagctgc tggcggatct
    10681 gatcgcccag cacctcctgg tcacgaacct ccgtgccccg atgaccacga tgaacccgct
    10741 gaaccacctt ctgagcgccc tcgacgcggc cgaagccgag aacctccagt cggccggcgc
    10801 caccgtcgcg cggcttcgat ctttcaccca cgctctggcc cggccccata cctcccccga
    10861 atacggcgaa caccgggccc agttcaacgc cgagatgcgc cacatcgccc ccggcaccgc
    10921 accggtactc gggaccgacc tgcggatcga cggggaggcg acggtcccga ccgcggtcgc
    10981 cgacgaagcg gcgcgggccg cgacggcact cgtacggctg gcccgccaac cgttcctcag
    11041 ccgcgcatgg gcgaactggc acggccgctt cctggagcgg tacggcccgc gcgccctgat
    11101 cccggtcctg gacgcagtgg acggtgacac cggcctcggc tatccggccg ggttcctcgg
    11161 cggaccgccc gccccggcga gcgccccgct gaccgagagg gacgggaaat tgctggcgct
    11221 cgcgcagaac gcggccctgc gccgtcagta cgagatcgtg gtggacgacg ccatgatcaa
    11281 cgctctcacc gtgatcggcc ccgacaccgg cgttcagccg acgacggagc tgatcgcccg
    11341 tatcaacgcc gccagcaccg acgccctcgg ggacggagag ttcacgctcg cggtcaccgg
    11401 ggtgtcccgg accgccggga cagtgactgg acggttcctc cacctcctcg acgcccacga
    11461 ccgcaaccgg atggcaacgg cgtacgcgac ggcggcgacc gcgaccgacg acgccctgcc
    11521 cgtacagata tccgcgcccc cgctccatac atccaccgag aacgtcgccc gtgccccggc
    11581 cgtgatgcct gcggtcctcg cctggggcga gtgccacgac cacatcgggg agcgggtgct
    11641 cttggatgac atcacggtga ccgccgatgt ccaccgcctc tacctggtct cgcggtcccg
    11701 gcggcgaccg ctggagttcg tgaacctcaa cgcggtcgag ccggtccacc gcacccatcc
    11761 gctggtccgg ttcctggccg aggccaccca cgcgatgagc gccccgtgcg cggtcttcga
    11821 ctggggaacc gcgacaacgc tgccgttcct tcccgcagtg cgctacggcc gcacgatcct
    11881 gtccccagcc cggtggctgc tcaccaccgc tgaccttgcc gcccgcgaga cggaccagcc
    11941 tcagtgggat gagtccctag tcgcgtggcg ggagcaggtc gccattccga gcacggtgta
    12001 cgcgggcgac ggcgaccaac gcctccgtct caacctggac gaacccgtgc accggatgct
    12061 gctgcgcgcg caagtacagc gttccggcac cgccgtgctc cgcgcggagg cggccccgga
    12121 cgcggggtgg atcggcgagc gcccccacga gctggtcatc cctctcgccc ggaccggccg
    12181 ggggcggagg gcaccgtggt ggctggaccg ggagaccggg acgccggacg ggcacggtca
    12241 tgtccccggc tgcgatggcc ggttcctcgt ccagctctac gcccgccccg aacgccacgg
    12301 cggcatcctg cgccgtctgc ccgaactgct ggcggagctc ggcggcagga cccagtggtg
    12361 gttcctgcct taccgcgatc ccgacgatca tttgcggctc cgcctcgtcg taccggccga
    12421 ccacgccgag ggcgccccag cggcgatcgg cggctggacc cgggccctgc gccgggccgg
    12481 gctgacctcc cgggtgcggt gggacaccga cttccccgag accgcccgct tcggcggccc
    12541 ggcggcgatc gacgcagccg agacgttctt cgcggcggac tccgaggccg ccgccgcgca
    12601 gctcgccttc agcacggcga acagcggccc cgacgcccaa gccgtcacgg ccgccagcat
    12661 gatcgacctc acgaccggcc tgatcgggaa ccccgccgac gcgatggcct ggctgattga
    12721 ccacgcccgc accaccagca ccgcccccgc ccgcgacgta tacgcacaag cggtcgccct
    12781 cggcaacccg tacgaccacg acgccctgac ccggcagccc ggcgggcagc ggatcaccgc
    12841 cgcgtgggcc cggcggcgcg agactctggc cgactaccgg gccgtgctcg acaccgcagg
    12901 cacagccgat gtgaacgtcc tgctgcccga gctgctgcat ctgcaccaca cccgcgtcgc
    12961 cgggatcgac ctcgacgccg aaggccagtg cctgcacctc gcccgcgccg ccgcgctgag
    13021 ctggaccgca cgaggaagga cccgctcgtg atacggatac cgaaggcgct ggccgtcgcc
    13081 gacggcctcg ccgccgaact ggccgacccg cgctccgcct cgcccgaagc cggcggtggc
    13141 cgggcctggc cgcagtccct ggccgggggc gcagcgggta tcgccctgct tcatgtcgtg
    13201 cgggcccgcg ccgggcgcgg cgactggggc accgcatgca cctggatctc ccgggcggcc
    13261 tccgacgacc tcgccgccgc ctccaatgcg ggcctctacc tcggtgcccc ggccctcgcc
    13321 ttcgttctgc acaccgccgc aggctcgacc ggccgctacc gcaacgcgct ggagaagctg
    13381 gacgacgcca ccatctcgat cacccggcgc cgtctggccg aggcccacgc gcggatcgac
    13441 gacggcgaac ggccggcgat gaaggagttc gacctgatcc gcgggctcac cgggttcgcc
    13501 gcccaccacc tcgcccgcca cccggaccac gagatcaccg ccgacacgct cgcctatctc
    13561 gtacgactga ccgaacccct cctggacggg gacgacgccc tgccctcgtg gtggaccgac
    13621 gtctctccca gcggggagcc gaccccggac ttccccgggg gccacgggaa cttcggactg
    13681 gcccacggca tcggcgcgac cctgtccgtg ctctcgctgg cgctcatgcg cggtgccgac
    13741 gctcccgggc tggccgacgc cgccggtcgg atctgtgcct ggaccgaccg gtggcggcag
    13801 ggcgacgaca ccgaaccgtg gtggcccggc ttcatcacgg ccggccaagc ggccggtggg
    13861 cgcatcgaat cggctctccg cccccggccc tcctggtgct acggcgtggc gggcaccgcc
    13921 cgcgcccaac aactcgccgg tctcgcactg ggcgagcccg cccgcgtccg cgccgccgag
    13981 aacgcgatgc tcgccgctct gcgcgacccg gcccaactgg accaggttcc cgaaatcggg
    14041 ctgtgccacg gaaccgccgg cctgctccac gccgcgtggc ggatggccga ccagaccgga
    14101 aacccggcca tcgcggcgga gctgccgcag atgaccgacc ggctgacggc tgcactcaac
    14161 cggtccgacc gggaccccga actcctcgac ggcaccgccg gtgcggccct ggtcctgcac
    14221 accgtcggca ccggaaccgt cgccgccccg tactgggaca ccttcctcgc cctggcctga
    14281 acccctggag acgacatgga cagccccacg tggcagcagg tgaacatctc cttccccgac
    14341 tggacccgtg ccgagcacac ggccctgaag cacctcgccc cgatcctgtt cgccgccgag
    14401 gacaacggcg agatcaccgc gtggttccac atcagcaaac gcccgtgctg gcgcctccgc
    14461 tacctgccgt ccaccgatac cgactcgcag atcggccggg aactggacgc gctgaccacc
    14521 gccggccgca tcaccggctg gactcccatc gtctacgaac ccgagatcca cgccttcggc
    14581 ggaacagaag ccatggaaac ggcccaccac ttcttccacc acgacagccg cggactactc
    14641 acctatctcc gcgacggaga ccaagacgcc ggcggacaca ggcgggagat atccctcctg
    14701 ctgtgcagca tcctgatgcg cacggccggc ctcgactggt acgagcaggg cgacgtctgg
    14761 gcacgcgtcg ccgcccaccg cccccttccg gtcggccggc ggagcaccgc ccgacaacgc
    14821 gccgccgtac accggctgct caccgtggat acgaacgacc agacctccga gaacggcccc
    14881 ctggcccgca ccagggaatg ggcccgtgcc tacacaaccg ccggccagga actcggcaac
    14941 ctcaccacca ccggagccct ccatcgcgga ctccgcgatg tcctcgccca ccatgtgatc
    15001 ttcgcgtgga accgcctcgg tctgccgtac gccacacagg ccgccctcgc cgccaccgcc
    15061 aaggacatcg tgttcggccc cgatcccgcc atttacggcg atgctgccgc tacgagcacg
    15121 gacaccggcg tttccaaccc cgtccagcct cgccgctgac aacaccggcc cgctcgccca
    15181 caggggaacc atgcacccga acgaccccat cgctcagcgc ttcccactcg tcgcccggcc
    15241 ccgtcccgcc tgcctaccgc tcaccgaacg catccacgca ttactcgacc tcgcccgaac
    15301 ggcggcagaa gagaacgatc cggcacgagc ctcagctgtc tacaaccagt cggctctcct
    15361 cgcctccgac ctcggtcttc ccaccctcgc ccgtgacctg tgccatcggc acgccgacgc
    15421 ctacctccac gcccgcccgc tgaccggcca gcgcgccatc caggcactcg aacccgtcgt
    15481 caacttcgcc cggctccaca tccgcgccgg gaacggagac gccgcccgac agcacctcct
    15541 tgcgctgtac gaggccgtca gcagggggac agcggtgcag ttggacagca tcgccgtccc
    15601 cgcacacctg accgcgacga ccgaggactg ccgcgaagtc cggacctggc tgtggacagt
    15661 tctcctcgcc gacgggacaa gggccctcac cgcccaaggc cggtggaacg acgcgctcac
    15721 ccacatccag aagcaccgtg gcatgggcga gcggatgctc gacggacggc aagtcgccgt
    15781 cctcgccgca ctcaccgcgg gcgacccagt ccccgccgcc gccctcctcc acgccactac
    15841 ccccggcgaa ccctgggaac aagtcgtgac ggcgtgcctc accgcgttat gccatcgagt
    15901 cgcccagcga accgctgacc tcaatgtgga aagcctggtg ggcatgtacg agaggctgga
    15961 gcccaaaccc ggaacggccg tcttcagcag ccgcctcggg ctgacgatct tggatgtcat
    16021 cggggccgac accgccaccg cccgtcgtgt cgcaaacgaa ctgcaccacc gggcgaccaa
    16081 gcagaacgac ggatacgcct cccttgagaa tctgcggcac cccctcttca acgccctcgc
    16141 caccgaaggg cagcagaggg attgccgaga gatcctggat gcgtgcgccc tcggggctgg
    16201 agaacttccc gacgagttac gcgaactgct catggcggcg gcgggcacga gcgaccgtac
    16261 gatccgaagg actatccttg tccgccagcg ccggtaaaaa cctggtgcat tggtaccccg
    16321 ccgcctcgtt ttccctcctt cgggcccgac agcggcctcc gctcgcacca gcccgccgcc
    16381 gactggtccg ttgagggacc atccggcaag cagccaggga ctttccgccg tgcaagcagg
    16441 gaaggccctg acagcgccga aagaaacaaa agcactggtc agggcccacc cgtcacaacg
    16501 ggctcagcac tcgatgatgt tcaccgcgag cccgccccgg gccgtctcct tgtacttcac
    16561 cgacatgtcc gcgcccgtct ccttcatggt cttgatgacc ttgtcgaggg agaccagatg
    16621 gctgccgtcg ccgcgcatcg ccatcttcgc cgccgtgacg gccttcaccg ccgccatgcc
    16681 gttccgttcg atgcagggga tctgcaccag accgccgacc gggtcgcagg tcaggccgag
    16741 gttgtgttcc atgccgatct cggccgcgtt ctccacctgg gctgcggtgc cgccgaggac
    16801 ctcggcgagg gcgccggccg ccatggagca ggccgagccg acctcgccct ggcagccgac
    16861 ctcggcgccg gagatggagg cgttctcctt gaagagcatg ccgatcgcgc ccgccgccag
    16921 gaggaaccgt acgatgccgt cctcgtcggc gccgggcacg aagttcatgt agtggtggag
    16981 gaccgccggg atgatgccgg ccgcgccgtt ggtgggggcc gtcacgaccc ggccgcccgc
    17041 cgcgttctcc tcgttgactg ccatcgcgta gagggtgatc cactccatcg cgagggccgc
    17101 cggatcgcct tcggcgcgca gctggcgggc ggtgttcgcg gcccggcggc ggaccttcag
    17161 accgcccggg aggatgcctt cgcgggacag tccgcgggcc acgcacgctt gcatgacctg
    17221 ccagatctcc aggagtccgg tgcggatctc ctcctcggtg cgccaggcct tctcgttctc
    17281 cagcatcagg gacgagatgg acaggcccgt gtcccgggcg agccggagga gttcgtcgcc
    17341 ggtgcggaag gggtacttca gcacggtgtc gtcgagcttg atgcggtcct cgccgaccgc
    17401 gtcctcgtcg acgacgaatc cgccgccgac cgagtagtac gtcttctcca ggaccgtgcc
    17461 gccgtcggcg tcgtacgccc gtatcgtcat gccgttggcg tggtacggca gcgccttgcg
    17521 gcggtggagg accaggtcct cgtcgaagtc gaaggcgatc tcgtgggcgc cgagcaggga
    17581 gatccggccg gactccttga tctgcgccac ctgctcgtcg gcggtctcca catcgaccgt
    17641 gcgcggggag ttccccgcca gcccgaggag gaccgccatg ggggtgccgt ggccgtggcc
    17701 ggtggcgccg agggagccgt acagctcggc ccgtacggcg gcggtgtgcg cgagcagacc
    17761 ctcgttcttc agccggcggg cgaacatccg cgccgcccgc atcggaccca ccgtgtgcga
    17821 gctggacggg ccgatgccga tcgagaacag gtcgaagacc gagatggcca cgtgaaactc
    17881 ctgagggtgg ggagacgccg ttgtctgccg cggtgcggtg gtgcgggtgg ggcaggggtg
    17941 aggctctggg gaaggggcgg tcggaggtcg ggagtgcggc gggggcaccg gctcaccttt
    18001 cagtgtgcgc gatgcccccg atgcccctac caatcgtaca aatgtacggg tatgggttac
    18061 ttcaggccgg ggtagagcgg gtgcttgtcc gccagcgccg tgacccggcc gcgcagggcc
    18121 tcggtgtcgt atccgggctt cagcgtctcc gcgatgatgt cggcgacctc gcggaagtcg
    18181 tccgcgccga agccgcgggt ggccagggcg ggcgtgccga tccgcaggcc cgaggtgacc
    18241 atcggcggcc gcgggtcgtt cgggatcgcg ttccggttga ccgtgatgcc gacctcgtgg
    18301 agccggtcct cggcctgctg cccgtccagc tcggagtggc gcaggtcgac caggaccaga
    18361 tggacatcgg taccgccgga caggacggag acaccgtgct cggcgacgtc ctcccgcacc
    18421 agacgctcgg ccaggatctt cgcgccctcc agggtgcgct gctggcggtc cttgaactcc
    18481 tccgaggccg cgaccttgaa ggacaccgcc ttcgccgcga ccacatgctc cagcgggccg
    18541 ccctgctggc ccgggaagac cgcggagttg atcttcttgg ccagttcggc cgtggagagg
    18601 atcacaccgc cgcgcgggcc gcccagcgtc ttgtgcgtgg tcgtggtcac gacatgggcg
    18661 tgcggtaccg ggttcgggtg cagcccggcc gccaccagcc ccgcgaagtg ggccatgtcg
    18721 accatcagat acgcgccgac ctcgtccgcg atccggcgga acgcggcgaa gtcgagctgt
    18781 cgcggatagg cggaccagcc cgcgacgatc agcttgggcc gggactcctt ggccagcttc
    18841 tcgacctcgg ccatgtccac tcggccggtg gcgtcgtcca cgtggtacgc gaccacgttg
    18901 tagagcttgc ccgagaagtt gatcttcatg ccgtgggtga ggtgcccgcc gtgcgcgaga
    18961 ttcaggccca tgatcgtgtc gccgggcttc agcagcgcga acatcgccgc cgcgttggcc
    19021 tgggcgcccg aatggggctg gacattggcg tgctcggcgc cgaacagcgc cttgacccgg
    19081 tcgatggcga tctgctcgac cacgtcgacg tgctcgcagc cgccgtagta gcggcggccg
    19141 gggtagccct cggcgtactt gttggtgagg accgaaccct gggcctccat caccgcgacc
    19201 ggtgcgaagt tctcggaggc gatcatctcc agcgtggact gctggcggtg gagctcggcg
    19261 tcgacggcgg cggcgacatc cgggtccagc tcgtggagag gggtattgag aagcgacata
    19321 tcggtaggta tccctgtcgt cagctcttgg tgaactcggc gtactcgtcg gcggagagca
    19381 gatcgtccgg ctcctccgcc acgcgcacct tgaacagcca gccgccctcg aagggtgcgc
    19441 tgttcaccag cgaggggtcg tccacgacgt cctggttgat ctcggtgacc tcgcccgaca
    19501 ccggggagta gaggtcactg acggacttcg tggactccag ctcgccgcag gactcgcccg
    19561 cggagacctg cgcgcccact tcgggaagct gcgcgaacac gacatcaccg agtgcgttgg
    19621 cggcgaactc ggtgatcccg accgtcgaca cgccgtcctc ggcggccgtc agccactcgt
    19681 gctccttgct gtagcgaagc tgctgggggt tgctcatggg gtgaattctc ctgtacgcgg
    19741 acggtgcgga tggacggacc cggcggcgcg gcgacgtgcg actggtcacg tcccgtgccg
    19801 gggcggcggt ggggaaggcg gggggtggtc cggggcgcgg gttacttctg ccggcggtag
    19861 aaggggagcg ccacgacctc gtacggctcg tgcgcgccgc ggatgtcgac cccgaccccg
    19921 gcggtcccgg gagcggcgtg cgcggcgtcc acgtacgcca tggcgatcgg cttgccgagg
    19981 gtgggggagg gggcgccgga ggtgacctcg ccgatcaccg caccgtccgc caccaccgga
    20041 tatccggcgc gcggcacccg gcggccctcg gcgatcagtc cgacgagggt acggggagga
    20101 gcgctcgcgg cccgctcggc ggcggcctcc agcgccttgc gcccgacgaa gtcgccctcc
    20161 ttctcgaact tgaccacgcg gccgagaccg gcgtcgaagg gggtgagcgc ggtggtcagc
    20221 tcgtgcccgt acagcggcat tcccgcctcg agccgcagcg tgtcccggca ggacaggccg
    20281 cagggcacca ggccgacggc cgcgcccgcc tcggtcagcg cccgccacag cccttccgcg
    20341 tgctcgggcg ccacgaagag ttcgaagccg tcctcgccgg tgtagccggt ccgggcgatc
    20401 agcgccggga ctccggcgac cgtgcccggc agccccgcgt agtacttcag cccgtcgagg
    20461 tcggcgtcgg tgacggactt caggattccg ggcgcctcgg gcccctggac ggcgatcagc
    20521 gcataggcgt cgcggtcgtc gcgtacctcc gcgtcgaagc ccgccgcccg ctcggtcacc
    20581 gcgtccagca cggtctgtgc gttgcccgcg ttcgccacga ccagatactc cgtggcgccg
    20641 gtgcggtaga cgatcagatc gtcgaggatg ccgccgtcct cccggcagat catggtgtag
    20701 cgggcgcggc cggggccgat cgtcgagata ttgccgacca gcgcatggtc gagcagggcc
    20761 gcggcctgcg gtcccgacac ggtgatctcg cccatgtggg agaggtcgaa gagcccggcc
    20821 cgggtgcgta cggcctgatg ctcctcgcgc tcactggcgt accggagcgg catgtcccag
    20881 cccgcgaagt cggtcatggt cgcaccgagc gagcggtgca gggcgtcgag ggcggtacgg
    20941 cggggggcag tgctcatgga cgggttctcc caggcatgac ggattccatg acgacgagga
    21001 cgttcctccc catctgtcat cggaacctga gaggttcgtc gcgaccccgc gtacggatgg
    21061 ccgtacggac ggaaagcgcg acttgcacct tgggtggggc cgacggacgc ggcccgcttt
    21121 tcagatctgc ctcatcgcac gcggtacggg gcctgagaga ttcaagggag gaacttgctc
    21181 cttcggcgcc cggggtcgtg ccccgggtct ctcccgcgcg gattcaagcg gccggtatgg
    21241 agttggcgcg cacatcattg cacgcgacac gggaagtggg ggagtcccgg cgtggttgtt
    21301 ctcggtacgg gagggacggt ccggcgcggg aagggcgacg cccggtccgc cgggagggcg
    21361 acgcccggtc cgcgggaagg gcacgcctgg tcacggacgc gtggcgggag cggcgcggag
    21421 acggccgccc ggccgcgggg aaccgcggag ggtgtcgcac cgctcttaac ggggaaaacg
    21481 gcgctgtgcg gggcgaagcc gggagaaacg cacgacacgg caggaggaac gtgagacgga
    21541 ttcgaggagc aaggcaggaa atgccggaaa aaacgctcgc atctcattac catttcttta
    21601 cggtccgttg atgatgcatg ggcatgtgtg tgggtgaccc gacatggggg aggagggtgt
    21661 gatgacgttg cagcgctcca gtgcctacgc cacgaccgcg ggggtgcccg cgcagccagg
    21721 agcacccgtg cgggagcggg tgggcgcgca tgcgccgccc gtgctgcgcg atctccgggg
    21781 ccgcgcgggc cgcgggccgc gggcgctcac cttcgcggcg ggtgatctcg tggtggtctc
    21841 cgggctgccg ggcagcggaa agtccaccct gatcaagcgc gcggtcgccg cggcgggagc
    21901 ccgcccggcc gccggctccg ccccggaagc cgtatcggcg gccgtatcgg ggcccgggcc
    21961 ggagtccggc tccgcggcgc cggagggagc cggtccggag gccggtcccg gcgccgccgg
    22021 ggaccccggc tccgtctgcg gcatcgattc gcaggacacc cgggaccgct gggacgcggc
    22081 cgtaccccgg ctccttccgt acgccctcta ccgccccttc gtccggctcg cccactacgc
    22141 cgggctgcgc cgcgcgctgc ggtccggccg gtccgtcgtc gtccacgact gcggcaccca
    22201 ggcctgggtc cggcgctggc tggcccgtga ggcccggcgc agaggcaccg ggctccatct
    22261 gatgctgctc gacgtcccgc ccgaggtggc ccgccagggc caggagcagc ggggccgcgg
    22321 ggtgtccgga tacgccttcg cccgccaccg gcgggccgcg ggccggctga tcgccgacgc
    22381 ggaggcgggc cgggccccgg cgggctgcgc ctcggtgatc ctgctggacc gccccgccgc
    22441 gaccgcgctc gcccggatcg gcttcaccgc cggctgacca ccgcccggac ggccggaccc
    22501 ggccccttac cgcagcacta gagtcggcgg cgcacattcg agcgggcccc gggggggccg
    22561 ggggagaggg cgaacaggga tgaacgtggc ggagcagccg gactcgcgat cgtacggagg
    22621 ggcccacggc ggcccgtatg cggcctggcc ggtcaacgag ctggaggaga ccctcgccgc
    22681 ctccctgggc aacccggacg cgggtgcccg gctggtcgag gtgctcggcc gcagccggat
    22741 ctgggttccg ctgcccaacg gcggcggacc cgacagcgtc cggctcgacc tgccgatggt
    22801 cgagatcggc ggcgcggcgt acgtccccgt cttcagctcc gaggagcagt accgggcctg
    22861 cgtcggcgac ggactcccgt acaccgtcgc accggcccgt gacttcgccc gcgggctgcc
    22921 cccgcaggtg ggcatcgtgg tcaatccgga cggaaccgtc ggggtcccgc tgccgccgcc
    22981 cgcggtcgcc gaactgtgcc gggccggccg cggtccgctg gacggcccgg cgagcggcgg
    23041 ccgggtccgg ctgttcgaac ccgactggca ggacgatccg gtcgacttcc tggccgccgc
    23101 ttcggtggag ttcggggcga cgggggtggt ggccaccgcg cgccggggtc tggcctccgt
    23161 cgagggcgac gacccggccc tcttcatcgg cgtccagctc ttccccgccg gaaccccgga
    23221 gaccgctctt gacgccctgg gccgggccct gggccgctgc gcggtccgct ggccggtgaa
    23281 cctggtcttc ctggacctga ccgaggatcc ggtggccgac tggttccgca cctccgtccg
    23341 gcccttcttc gagggggagc tccggctccg cggcggcgcg gggatccgtc cgtagccccg
    23401 gcggcccgta gggggggcag gcccctccgt acggcccgcg gggaaccgcc cggcggcccg
    23461 gcctcgtcac ggaggacagc accaaacgaa ggggcgcgcc gtaagctggg gggcggcccg
    23521 gggccgtggg gccgggggca cggacgaccg ttgggacaag aggggcggaa caaggtgagc
    23581 gcgtcaggca cggcggcggc cggtcagatc gagcacatgc tccgccaggt gaccccgggg
    23641 cgctacgacg cgtacgaggc gctgctggcg gcactcgccg agccggccgg cggccgggtg
    23701 tggatgctgc tgtggaacgg ccgccccggc acaccggacg cccagtacgg caatctggag
    23761 gtcgacggcc acggctacgc gcccgccgtc acctccgccc aggaactgtc cgcgtcgagc
    23821 tggagccgcg cccacgaagt ggtcagcggg ctcgatatcg cccgggccct ctaccccgac
    23881 cgctggggca tctggctcaa tccgcatgcc cccggcggcg gggtcggcat cccgtggacc
    23941 gatctgcggc ggatcgcgac cgggctcgac cggatgcccg ccggtccgct gcggctctcc
    24001 gaacccgcca tcgacatccc ccagttctac gccctgctgg cgcgcaacgc gcatcagacc
    24061 ccggccgtcc gctcgctgcg gcgcgcctgg gtgcagcccg cgctcggcgc cccgtatctg
    24121 gccatcgggc tggatctgta cgacaccagc cgcccgtccg tggacgcggt gcgggcgatg
    24181 atgcagcagt cgatcgcggc ggtgcccgac gggctgccgg tgtcgacggt cgcgctctcg
    24241 gacgagtacg acccggtggg gatgtggctg ctggcccacg cccggccgtt ctacgaccgt
    24301 gaggcccacg ccgctcccgg cgccggcggc tacggctatc cgccggccgc cggccgctga
    24361 ccccggccca cccggccgga gccggccccc ctgacaccgg gctcggcgga gactgtccgg
    24421 aacccctcct ccggtgaccg ttccggccat ccgacggttg tccggcacac cgtgaccggc
    24481 cgatggacgg ccgaatatcg cgtacccgtt cggcgatggc cgtagtgctc cggtccgccg
    24541 atgtttcccc ctcaagatcg ccttaagggc gaggaatcca gggatgtcat ccgtggcagg
    24601 cctttgattc acagggcgcc aactgtccga taatcggaaa ctggctcaac ttcccatgat
    24661 tcacggagag atggcgtccc gctcagcctt cgaaaccgtc cggataacgg atcccctccc
    24721 catgcatcac gtttgggcaa ccattggccg ggaggtctgg cgagtgatcg cggcaccgtt
    24781 gaagactccc gcagcagggg gacactcgtc cccgcgcgcc gccgggtcaa acgtacgttt
    24841 cgtaccaact gctccaggtg caccagatgt tgtgaaagaa gccgctacag cggcgggtac
    24901 gggccggtca cctccggccg agaggggtcc ccaccacgat gacggcacca atgcacgaca
    24961 cgagcgcgga cgcggagaag gccgcgaccg ccgatgtcgc ggcggctgta gtcaagaagt
    25021 ctgtcgaagg gcggtcgctg cggcagatcg cctggtcccg gctgaagcgg gacaagctgg
    25081 cgctggcagg cggcatcgtt gtcatcttcc tcgtgctcgt cgcggtcttc gccccgctga
    25141 tcgtcgatct gttcggcca
//
