LOCUS       NZ_CP042266            22667 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces qinzhouensis strain SSL-25 chromosome, complete genome.
ACCESSION   NZ_CP042266
VERSION     NZ_CP042266.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qinzhouensis
  ORGANISM  Streptomyces qinzhouensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8146484)
  AUTHORS   Zhu,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2019) School of Life Science, Hunan University of
            Science and Technology, He Ping Street, Xiangtan, Hunan 411201,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007856155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 04:30:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,577
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 28 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 9 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:37:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2521925
            Orig. end                         :: 2544592
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP042266.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22667
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="8"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22667
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22667
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12667](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12667)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(787..1818)
                     /locus_tag="FQU76_RS10415"
                     /old_locus_tag="FQU76_10415"
     CDS             complement(787..1818)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019764741.1"
                     /locus_tag="FQU76_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10415"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_146480163.1"
                     /transl_table=11
                     /translation="MTHTTATTAHHRPRWWTELALLALVYVAYSAGRLLARGDVSTAVD
                     NGLAILRAERLVSLDFETPLNRLFTEHAAIGVPADFVYASLHYLVTPAILVWLFRRRPL
                     QYRAARTWLMVSTLLGLVGFILMPTCPPRLLEAGQGFVDTMAQYSSYGWWGAEASAPRG
                     MGGFTNQYAAMPSLHVGWALWCGVLLWRYGRTPLMRTLAVAYPLVTVIVVMGTANHYFL
                     DAAAGAAVMGAGLLLAKPAMRLADRVRVRFARGGAAAPAAAGAPVVGGGCHTSTGERIP
                     GQRTSSAAGTTSTTSTTSTTTSTTITADTTSTAGASPDAASGAVAHRSHAGGADDAASA
                     AAR"
     gene            2035..2637
                     /locus_tag="FQU76_RS10420"
                     /old_locus_tag="FQU76_10420"
     CDS             2035..2637
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123287.1"
                     /locus_tag="FQU76_RS10420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10420"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_146480164.1"
                     /transl_table=11
                     /translation="MAPRILLVRHGQTEWSLLGKHTGRTDIPLVAEGRRGAALLGERLR
                     GAPFGGLPDVEVWTSPLARAAQTCELAGFGDRAEPWDALMEWDYGDYEGRTTPEIRADG
                     RPGWVIWRDGVEGGEKLTDVAHRADEVVARVREADRDVLLFAHGHVLRVLCARWLGLEP
                     EFAARISLAPTSLSVLGWAYGDPALDSWNDTAHLDSL"
     gene            complement(3024..3227)
                     /locus_tag="FQU76_RS10425"
                     /old_locus_tag="FQU76_10425"
     CDS             complement(3024..3227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957445.1"
                     /locus_tag="FQU76_RS10425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10425"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_146480165.1"
                     /transl_table=11
                     /translation="MTTATNLTWVKSSYSGQGGQCIEWAPEYASATDIVPVRDSKNPDG
                     PALMISTSAFAGLVTLARTSEL"
     gene            complement(3224..4054)
                     /locus_tag="FQU76_RS10430"
                     /old_locus_tag="FQU76_10430"
     CDS             complement(3224..4054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008404599.1"
                     /locus_tag="FQU76_RS10430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10430"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_146480166.1"
                     /transl_table=11
                     /translation="MSNRKQLHPERSPREKFGLLVRTLRDERGWTQEELAERVGCTGSH
                     ISAVETGRRAATQQFARKLDRVFGTGARLEQQIQAARYTALLEGFPEYVAREAHAAEIR
                     LYEVGVIPGLLQTPQYAAAIEDQEVKRGAITPEQAHERVALVESRQAALVRTPPPLVFV
                     ILDESCLLRPVGGRSVMGVQLARLLEFADNPHTALHVAPFSMAERRPYTLPITILTLPD
                     RGLMAYAQSSQHGHFERESAAVVPMLAAYHQLHVGALSQDASVDMIDQIRKGTT"
     misc_feature    complement(3542..3544)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(4066..4080)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.49"
                     /tool="antismash"
     gene            4160..4381
                     /locus_tag="FQU76_RS10435"
                     /old_locus_tag="FQU76_10435"
     CDS             4160..4381
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953306.1"
                     /locus_tag="FQU76_RS10435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10435"
                     /product="hypothetical protein"
                     /protein_id="WP_246150371.1"
                     /transl_table=11
                     /translation="MPEDIHVGGLAYDTVNKCIGVVMDTYGGRIALRPPAGGCEWDVRR
                     EDVRPATVFDRIRAELADVNAQSSKGMP"
     gene            4399..4605
                     /locus_tag="FQU76_RS10440"
                     /old_locus_tag="FQU76_10440"
     CDS             4399..4605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS10440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_10440"
                     /product="hypothetical protein"
                     /protein_id="WP_146480168.1"
                     /transl_table=11
                     /translation="MPTLPVLAHMTCESGTPPCRAEPSAGAGQLTAGEVASWAREHVLT
                     TGHTDFELLVSSYVRWESSGDVS"
     gene            4707..5039
                     /locus_tag="FQU76_RS33865"
     CDS             4707..5039
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640336.1"
                     /locus_tag="FQU76_RS33865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_186768429.1"
                     /transl_table=11
                     /translation="MFRWLRGQALSLADRLDPDPAQVTWASVLHPEPATRYSGIADVPW
                     ALRAWAANGANRRDERRLAAGIPVFMLRADRTGSYAFIAWPVGPGTTPPDDALRWLSAA
                     GYEWSQ"
     gene            5036..5461
                     /locus_tag="FQU76_RS10445"
                     /old_locus_tag="FQU76_10445"
     CDS             5036..5461
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346486.1"
                     /locus_tag="FQU76_RS10445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10445"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_246150373.1"
                     /transl_table=11
                     /translation="MTRESDHTVAVAVAVIVRPVDGRIVLVRRRVPESELVWQFPGGKV
                     EPGEAPEAAAVRETREEIGLTVVDRARIGARIHPLTGRRIVYIACDVVSGVAQVTAPRE
                     IAYTAWIPPSRLDTYAPGVYEPVRQYLSITAPGRKSP"
     gene            5458..6603
                     /locus_tag="FQU76_RS10450"
                     /old_locus_tag="FQU76_10450"
     CDS             5458..6603
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963006.1"
                     /locus_tag="FQU76_RS10450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10450"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_186767994.1"
                     /sec_met_domain="PCMT (E-value: 3.6e-09, bitscore: 35.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAWNWETRAGALADRVTDPDSRWLAPLAVVPRHRLVPRWWERDH
                     DGRWALRIGSDDPVAWMDAAYGDQSLVTRVGTLHADHAEPDDHPEGRPTSSATMPSLVV
                     SMLRYARLGAGLDVLDVGTGAGGLAAYAATRFGARHVTSLDVDPYLTGAAAERLSGLGL
                     KPGFRTQDATTEITGTYDRIIATVGMPPGPGLRPLLGALHPGGRLVTALDRMGVIITGW
                     KRADGDVVGTVERTPAGFMPARSGADYGPTPDFAVAEAADGQSVSTGRYPVLDIPNTWE
                     LRSMLELAAPGVEATFHEQGRTRTACLIHPDGSWARASAEWTDPPTVQQSGPRRLWDVL
                     EHIRTRLNIEGSLPLLGARVRITPDGVCHFSRGQWRAAIGA"
     gene            6703..7008
                     /locus_tag="FQU76_RS10455"
                     /old_locus_tag="FQU76_10455"
     CDS             6703..7008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952366.1"
                     /locus_tag="FQU76_RS10455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10455"
                     /product="hypothetical protein"
                     /protein_id="WP_146480170.1"
                     /transl_table=11
                     /translation="MRDSIARALAWVLSLFFPARGRHRAPKPSTPVIICAPLLARTMPV
                     PERLSIPPYTDTCSARQEQEEQRRRERRTALAFAVIGIDYPYVAEGVHQVTTGVAA"
     gene            7005..7202
                     /locus_tag="FQU76_RS10460"
                     /old_locus_tag="FQU76_10460"
     CDS             7005..7202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006348718.1"
                     /locus_tag="FQU76_RS10460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10460"
                     /product="hypothetical protein"
                     /protein_id="WP_146480171.1"
                     /transl_table=11
                     /translation="MTREGLLTSAPEPFTAPCVHCGRTTTAPVVVGVTERASGPPMVQY
                     ACPQDAARYGAGPSPEDEIG"
     gene            complement(7340..8704)
                     /locus_tag="FQU76_RS10465"
                     /old_locus_tag="FQU76_10465"
     CDS             complement(7340..8704)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS10465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_10465"
                     /product="hypothetical protein"
                     /protein_id="WP_146480172.1"
                     /transl_table=11
                     /translation="MTGISRRSVLRGGAVVGVASASGGVHTAAQATAAGVNPSVPGEAA
                     HVRRLRKALDDAAAGIAGPDGVDSAGRIIVKAGYAGVPTYTLLNTLVIGGNTLLDATGA
                     RFVAKFGTAGREYKLDKTNDHSPTPVYQVDGQGMFTAPEVSGAKAATMLINHVPAATTK
                     GYAAPGNIKIKGGEWDPISAYVWEDTGAARARADKAPPMNALTFIHTQDIEIEGVTVYN
                     VKWWHAVELNAVRRAVVQDSFFKGWVENPTAGLWQGEAVQLDLPSTSNTWAGAADGTPT
                     VDVRVLRNHVAASGSQPSWAKLIGSHTGGQKAGQVHARVLIEGNVVDDAKWDAIGPMNT
                     TALVIRGNTVNRGCGGVYVSPMTAKTPVQPPVPVAANPLNGVEITGNTVTLARSAAGVT
                     RHAVRINSVSEGGFDSKVTDVVVTGNTATGDSVNGKRYSYGPLVEFRPGVPPQND"
     gene            complement(8895..9920)
                     /locus_tag="FQU76_RS10470"
                     /old_locus_tag="FQU76_10470"
     CDS             complement(8895..9920)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043655.1"
                     /locus_tag="FQU76_RS10470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10470"
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="WP_246150375.1"
                     /sec_met_domain="PCMT (E-value: 7.7e-24, bitscore: 83.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPVALAAETVPERHYTHHEGRGATPHRSNPKVIHRELTTLDVRP
                     DMNVAEFGTGSGYSGALLAHLVGPQGTVTSLDIDDYLVRWAGLIHHQRGVGNIRCHTAD
                     GTAGFADRAPYDRIVAWCTPPLLPRAWVDQTADGGLIVAPLPIAAVPNMTLVAKIRVSG
                     CQPSVEAVFNGGYIEATTSPKTDLDLPGRWIDWENRVPAPSWISVAWREGDDDLHTGAR
                     TTLDRLLNNAHTEPYDGPKLDWPSWRTWAAATAGPQLTMAGLNPDLWALGHSTPTTAAV
                     IQQDATVLADTVDSPSLTALRGWLSAWEDAGRPAPETHRTTLVRYDDGQGADGWNLRLT
                     P"
     gene            complement(10001..10423)
                     /locus_tag="FQU76_RS10475"
                     /old_locus_tag="FQU76_10475"
     CDS             complement(10001..10423)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024862.4"
                     /locus_tag="FQU76_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10475"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_146480174.1"
                     /sec_met_domain="PF13471 (E-value: 1e-10, bitscore: 40.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSTEAYSTTRTGTFPERVAALAGIALALVLLRLPFRHTVRAVRW
                     ARRLGHRPLTPARADALVAAVRHAGRWWPGRVACAETSLGSALAAAFLRQELTWCLGAR
                     FLPPPTEYHAWTELPGAGPVGEYTEGGWHHYAALRI"
     gene            complement(10420..10716)
                     /locus_tag="FQU76_RS10480"
                     /old_locus_tag="FQU76_10480"
     CDS             complement(10420..10716)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS10480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_10480"
                     /product="HPr-rel-A system PqqD family protein"
                     /protein_id="WP_146480175.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-09,
                     bitscore: 36.9, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWQLRDGTHPVLTDEGGAILDELTGRWTHLTPTAAAAVMLLLAGN
                     TPAQAAVEYASRYRLTTDHARDDIRTVSNALTSAGLARKAPAPHRRCWWGWWR"
     aSDomain        complement(10468..10713)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FQU76_RS10480_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.40E-12"
                     /identifier="RREFam002.1"
                     /label="FQU76_RS10480"
                     /locus_tag="FQU76_RS10480"
                     /protein_end="83"
                     /protein_start="1"
                     /score="36.9"
                     /tool="antismash"
                     /translation="WQLRDGTHPVLTDEGGAILDELTGRWTHLTPTAAAAVMLLLAGNT
                     PAQAAVEYASRYRLTTDHARDDIRTVSNALTSAGLAR"
     gene            complement(10700..12667)
                     /locus_tag="FQU76_RS10485"
                     /old_locus_tag="FQU76_10485"
     CDS             complement(10700..12667)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="FQU76_RS10485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10485"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_146480176.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.6e-24, bitscore:
                     85.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRLRRHQGAGSARLPCLGHGAGGPAPSRFYETTQVRARKGAQMR
                     WSAGWYGDSACDRLPAGGRAVPGLDAAWTCGWPSARIRTAGEGRAVLAVIGECGADDRE
                     LATAPALVRAGKWRALTRWPGSYLTIARSGPVLAVIGDLTGQHPVYWRTDAAGTWWATS
                     ASALASLDGAPVDPVGLAAHLAFGQPDVLGERSLFRTVRRVPPGHLLLIGPEEAGTVPY
                     EPAVYEPVDLHQAGPVVRAALFEAVAARIDDRPVSADLAGLDSTTLACLAARSGPVTAV
                     TFADPRLRDDDLTYAARTAATVQGLRHQVVSGNPDTVYYQGLDDLAALPVTDAPNAYTV
                     TAAIKRAVLDAVAARHTVPGVHLTGAAGDALLSAPSSYLADLLRTRRRRDAWRHALGHG
                     RLRHTSAFTALRRARPAGRTALPGAWRQIAADLRGPVRAWVPQAQRPVSWTPLLATADW
                     MSPEARSRLADALIRAADELADPPTLLAPWVDRQDLVRVGANTGGWREIALAGYGIELA
                     APYLDNEVVRACLAVPAEQRGAPGRYKPLLASAFTGTGVLPGFVLARVTKGGFNALAYD
                     GLRRHAGQLRDLLGPASRLAALGLAAEAPVNAMLKRAAAGQPTAQGALHLVTSAEIWLR
                     RLDTAPAPVWRKVDSRVATA"
     gene            complement(12707..12832)
                     /locus_tag="FQU76_RS10490"
                     /old_locus_tag="FQU76_10490"
     CDS             complement(12707..12832)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="FQU76_RS10490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10490"
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_186767996.1"
                     /transl_table=11
                     /translation="MEDTLTAVYEAPVVLDAGAVVEVTLGTETFDTADDTEYKNA"
     CDS_motif       complement(12758..12832)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MEDTLTAVYEAPVVLDAGAVVEVTL"
                     /locus_tag="FQU76_RS10490_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12707..12757)
                     /prepeptide="core"
                     /locus_tag="FQU76_RS10490_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-0.70"
                     /molecular_weight="1759.7"
                     /monoisotopic_mass="1758.7"
                     /core_sequence="GTETFDTADDTEYKNA"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MEDTLTAVYEAPVVLDAGAVVEVTL"
                     /leader_location="[12757:12832](-)"
     gene            13022..14398
                     /locus_tag="FQU76_RS10495"
                     /old_locus_tag="FQU76_10495"
     CDS             13022..14398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521721.1"
                     /locus_tag="FQU76_RS10495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10495"
                     /product="hypothetical protein"
                     /protein_id="WP_146480178.1"
                     /transl_table=11
                     /translation="MTQRMPNHQLSELIEESGLPYDGIARAVRAVATESGQHLGTNKSA
                     VHHWVAGVVPSGSTPQYLAEALSRRLGRRITREDLGLPSPGSGEDGSIGLTLDFDPVEI
                     LAAIGKADVNRRRFLSASAYSMAAAALPLETVRETAARARAAASGAMAGHADVAAVRDM
                     VRFFMDMDERHGGQHGRSAFVQYLVTDVLDLCRSRFSSEQARAEALSVASAGAHLAGWK
                     AYDSGEQGLAQRYYLQSLALARESGIPGQDGFVMRTMSQQGMKLHRAEHCLALAETGWA
                     RARGRVDGQTEALFAITHAHALAKTGQTNRALAGAKQAHASLTAGADDQVPFWALVWGP
                     PAATVHSRTAKVFETLGDRPNAARQYATAAASRPGATYARIIALDLVAEAEQQAKQGSI
                     EQACATWTRAINTMDGVRSARTRKAIRSLRGELNIYRARGLRCATELDEHARAFLANQR
                     "
     gene            15008..15349
                     /locus_tag="FQU76_RS10500"
                     /old_locus_tag="FQU76_10500"
     CDS             15008..15349
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349157.1"
                     /locus_tag="FQU76_RS10500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10500"
                     /product="hypothetical protein"
                     /protein_id="WP_146480179.1"
                     /transl_table=11
                     /translation="MTEAPQGHRKPRPAALLFEPAEAVADPEHFFDLEAMDDPRALLAR
                     ATELTLAFRAATDRAVEYQALAAAQLADPRRFDRMTPGDIAERAGWTEDYARKMIEFGR
                     GLAREDGHA"
     gene            15632..16306
                     /locus_tag="FQU76_RS10505"
                     /old_locus_tag="FQU76_10505"
     CDS             15632..16306
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349156.1"
                     /locus_tag="FQU76_RS10505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10505"
                     /product="hypothetical protein"
                     /protein_id="WP_246150377.1"
                     /transl_table=11
                     /translation="MSASTSAPLRNDHRLPHASAEEDRRQESARGAARITAAGADWLAA
                     AGAGPRPQAERCPGAPAVLSCGRLFDVVSAPAVFGRLLLDRMWEEGPGSGPVAAHRGRM
                     LVFTTPGTAARLPALLSWEEWGGFVPALMFHGRGDAVTVPPLAAPGGGDPGVAPRWLVA
                     PGARHPWLPGPEVLLWACVRAVKAARAVAGAVRTGAPAGPYGPISPLPDPGANVYDVSR
                     RR"
     misc_feature    15656..15658
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            16297..16370
                     /anticodon=(pos:2538256..2538258,aa:Lys,seq:ctt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="FQU76_RS10510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="FQU76_10510"
                     /product="tRNA-Lys"
     gene            16297..16370
                     /locus_tag="FQU76_RS10510"
                     /old_locus_tag="FQU76_10510"
     gene            complement(16443..17795)
                     /locus_tag="FQU76_RS10515"
                     /old_locus_tag="FQU76_10515"
     CDS             complement(16443..17795)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960588.1"
                     /locus_tag="FQU76_RS10515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10515"
                     /product="M6 family metalloprotease domain-containing
                     protein"
                     /protein_id="WP_246150379.1"
                     /transl_table=11
                     /translation="MERQQSPTGPPGSVGGGRLCGSDGSGAAGGRGDGGRANGGAGGTG
                     GERSRARSAAAALTSLLALAATSLVAGPAVAKASSASCALARTPAHHSLGLDTWNTAYP
                     RPVRSLDAVMVFLSFPDSAPRTTPAQLTADHFPATSAFFERASYGRFALRAHPQPAWVR
                     MPKASTDYGIRRDWGAGQRRTFLRDALGAADRTVDFSRYDIVYLVADPDAPGVDSDATK
                     VVNFAQPMTYDGTGLRRVVTVFEQHPPDRNVLAHETGHVFDLPDLYQRPVDGKGDWDTY
                     VGDWDVMGSQFGLAPDLFAWHKWKLGWLATGDVRCVTRPEMITLEPVGAAPAPGGALGT
                     RLAVVRTGAGTALAIEARGAAGNDRTTCTEGILLYRVRADTVSGGGPVEVIDTHPETEA
                     CWDRSVYPKLADAPLGVGETFTLAGGSGERIRIEVADRTATGAWTVKISTG"
     misc_feature    18166..18181
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.85"
                     /tool="antismash"
     misc_feature    18203..18212
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     gene            18322..20109
                     /locus_tag="FQU76_RS10520"
                     /old_locus_tag="FQU76_10520"
     CDS             18322..20109
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608732.1"
                     /locus_tag="FQU76_RS10520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10520"
                     /product="EAL domain-containing protein"
                     /protein_id="WP_281292835.1"
                     /transl_table=11
                     /translation="MSGTPEGTGPGRDYRAAFDAAPLPMAVVGADGLVTGANPAFAGLF
                     GGDTTGRSAEELTGLAADHDNRKTYRDVLRGRRPRLCCTRRVKRADGGTLWAEITLTPL
                     TGPGENGRDGDNGRGGADSGDGRGALLCVTDVGERRELRARLRHLEMHDAVTKLPNRAL
                     FFERLTAVLESAAYERGATGRIGLCYLDLDGFKAVNDTLGHRIGDKLLTAVAARLAECA
                     ESVGASRGGGHLVARLGGDEFAVLVEESTGTEQLADLARSVLAALQRPFDLDGQRLSVS
                     ASIGVVERAAAGTSATALMQAADTTLYWAKEDGKARWTLFDPERNAHRMTRQALSSSLR
                     PALERGEFALEYQPLVGLADGVTHGVEALVRWHHPRFGTLAPNRFVGIAEEDGSIVQLG
                     RWVLRTACRQARRWQLDHPGSRSLFVSVNVAVRQVWDSDLVADVAQTLEETGLPAHLLQ
                     LELTESAVMGSAGRPLQALQALSDMGVRIAIDDFGTGYSNLAYLSRLPVSALKLDGSFV
                     RGFQDEAHPNPADETIVEALVQLAHRLGLTVTAECVETAGQAARLRRIGCDSGQGWLYS
                     RAVPPDRIAELVGLTALPA"
     gene            complement(20461..22119)
                     /locus_tag="FQU76_RS10525"
                     /old_locus_tag="FQU76_10525"
     CDS             complement(20461..22119)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349153.1"
                     /locus_tag="FQU76_RS10525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_10525"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_146480181.1"
                     /transl_table=11
                     /translation="MRSRKPLIAAMTTAALAAGVLAGFAATGNAATPQQTAAATPAQTG
                     VKIAYYDQWSVYGNAFYPKHLDTRGIANKLDIINYSFGNIHPTDLTCFQANKAAGDDNN
                     PNAGDGAGDSYADYQRTFSAADSIDGVADRWDQPIAGVFNQFKKLKAKYPHLKINISLG
                     GWTFSKYFHDAAKTDAARKKLVSSCIKQYITGDVPKADGYGGPGTAAGIFDGIDIDWEY
                     PGSNGGHLGNHYGPEDKANFTLLLAEFRKQLDAYGTANGGKKYLLTAAMPAGQDKIKHI
                     ETDKVGAYLDYANIMTYDMHGAWNGTGPTYHQSPLYSPPSDPTNPIAPGTEKYSVDNAV
                     RAWIDGNPAYGIAGGFPANKLTLGYEMYYRGWKNVPAGTKNGLGQSANGGSAPRPLSQA
                     AGIANYKELGGIVDNPATTFWDDEAKAAYFYKNGEFFTGLDKRAIDARAAYAKSKGLGG
                     AMMYSLIGLDEQTKLLNDVVAAVGESVRPSPTPTPTPTPTPTPACGEAWTATGVYNTNA
                     IASHNGRKWKAQWWTQGNEPGTGGEWGVWRDQGAC"
     misc_feature    complement(22218..22233)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.23"
                     /tool="antismash"
     misc_feature    complement(22245..22260)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.92"
                     /tool="antismash"
ORIGIN
        1 accgcggcgg acagctcgtc ggacggccgg tcgagggcga aggtcgtgcc ctccgggagg
       61 gccgccgcga ggtcctcgac ccgggtgagc cgggccagct ggcgacgggt cacggacagc
      121 tgcttacgga tgtccacgaa cgatccggtc ggcagattgg agaagtcctt ggggcagacc
      181 agcagcacgc tgtccgcgac ccgggcgccc ggcaccagcc gggcggtgtg ctccagcgcc
      241 agcgcgtaca ccgcggcctg gcgggcggcg gcgcccacct tcgaggcgtc ggcggaggcg
      301 tcgatcatcg ggaaggactt gatctcgacg accgtccacc cgccgtcggg gcggaccacc
      361 accgcgtcgg gctccagata ggccggggag cccgcgacct ccagcgccag cagcggatgc
      421 cgcagcaggc tccaggctcc cgcggcggtc gcctcgcgca gcgccagcgc ggtgcgggcg
      481 gcccggccct ccggtcccgc ggcggacaga tcgggcagcc ggaacccgcc ctccgcctcg
      541 gcccccagca gtctcatcag ctccgcgccg ccgtccgaaa cgaccctggc ctcgaaggcg
      601 ttcccccgca tgaaggcgaa ctgcgactgg ccgaagaccg cggtggagcc cagcgcggcg
      661 gccagggcgc ccttgtcgac ccccgcgccg tccagcaggg cacggcgctc gcagccggga
      721 ttggcggcca gggcggccag cgcccgggcg tcgagcggcc ggggccgggc cccggcgccc
      781 ctcagctcag cgagccgctg ccgaagcggc gtcgtcggcg cctccggcgt ggctgcggtg
      841 cgcgacggct cccgaggcgg cgtccggcga ggcgcctgcg gtgctggtgg tgtccgcggt
      901 gatggtggtg cttgtggtgg tgcttgtggt gcttgtggtg cttgtggtgc ctgccgcgga
      961 ggaggtccgc tgccctggga tgcgctcacc cgtggaagtg tggcatccgc caccgacaac
     1021 cggggctccc gcggccgccg gagccgccgc accgccccgc gcgaaccgga cccggacccg
     1081 gtccgccagc cgcatcgcgg gcttcgccag cagcaggccc gcgcccatca cggccgcccc
     1141 ggcggccgcg tcgaggaagt agtggttggc cgtccccatc accacgatga cggtgaccag
     1201 cgggtacgcg acggcgagcg tccgcatcag cggcgtacgg ccgtaccgcc acagcagcac
     1261 cccgcaccac agggcccagc cgacgtgcag gctcggcatc gccgcgtact gattggtgaa
     1321 gccgcccatc ccgcgcggcg cgctcgcctc cgcgccccac cagccgtacg agctgtactg
     1381 ggccatggtg tcgacgaagc cttgaccggc ctccaggagc cggggcgggc aggtcggcat
     1441 caggatgaac ccgacgagac cgaggagggt ggagaccatc agccaggtcc gggccgcgcg
     1501 gtactgcaac ggtctgcggc ggaacagcca gaccaggatc gcgggcgtca ccagatagtg
     1561 cagtgaggca tagacgaagt ccgcggggac gccgatggcg gcgtgctcgg tgaacaggcg
     1621 gttcagcggg gtctcgaagt cgagggagac cagccgctcc gccctgagta tcgccaggcc
     1681 gttgtcgacg gccgtcgaca catcaccacg ggccagcagc cggcccgccg aatacgcgac
     1741 gtacaccagc gccagcagcg ccagctcggt ccaccagcgt ggccggtggt gagccgtggt
     1801 ggccgtggtg tgcgtcatcc gttcgttccc cctcgtgcgc gttcgccggc cggaccggcc
     1861 accggtccac cgtacggtgt acgacgcggt gccgggtcag cgggtaccgg ctcagagagg
     1921 gacgctccgg gcactgtgga ggttgcctcg gccgcccggc cgcgctcccc ggatcggtgg
     1981 ccggaccatg catgatggag gcccacttct ctgatcatca gggggcttcg caccatggca
     2041 ccgcgcattc tgctcgtccg gcacggccag accgaatggt cgctgctcgg caagcacacc
     2101 ggccgcaccg atatccccct ggtggcagag gggcggcgcg gggcggccct gctgggcgaa
     2161 cggctgcggg gcgctccctt cggcgggctc ccggacgtcg aggtgtggac cagcccgctg
     2221 gcccgcgcgg cgcagacctg cgaactcgcc ggcttcggcg accgtgccga gccgtgggac
     2281 gcgctgatgg agtgggacta cggcgactac gagggccgta cgactccgga gatccgggcc
     2341 gacgggcgcc cggggtgggt catctggcgc gacggtgtcg agggcggcga gaagctcacg
     2401 gacgtggcgc accgggccga cgaggtcgtc gcgcgggtcc gcgaggccga ccgcgacgtc
     2461 ctcctcttcg cccacgggca tgtgctgcgg gtgctgtgcg cgcggtggct gggcctggag
     2521 ccggagttcg cggcccggat ctcactggcc ccgacgtccc tgtcggtcct gggctgggcg
     2581 tacggcgacc cggcgctgga ctcctggaac gacacggcgc atctcgactc cctctgaggg
     2641 gtgcgccccg ggtccctggg ggcggttcgc cctggcgggt gcgggtcccg ggtgccccgg
     2701 ggtggcctac ctggcggtgt gagggtcctg cgggccctgt ggctggtcca cctgcggtgt
     2761 gcgggtttct cgctggtcga gtcgcgtttc tccgtggggt atgaccaggg ccctgtccgg
     2821 tgcggccggg tcggtggcct ccgggctcac ctcctcgcgg cctgcgatgc accgcccata
     2881 agcgcctcct ccttgtcgca ggaccactgc gggggcgacc ctgcaccccc ctccggagac
     2941 actcaactcg atcagcggca cgaggctcag cacaactgag ccccgtacgg agcggccgta
     3001 cggggctcgg ggtgcgcggt tccctacagc tcggaggtcc gggcgagcgt caccagtccg
     3061 gcgaacgcgc tggtggagat catcagtgcg ggaccgtccg gatttttact gtcccggacc
     3121 gggactatgt cagtcgcgga tgcgtactcg ggggcccact cgatgcactg cccaccctgg
     3181 ccgctgtaag aagacttgac ccaagtcagg ttcgtcgcag tcgtcacgtg gtgccctttc
     3241 ggatctgatc aatcatgtcc actgaagcat cctgggacag tgcccctacg tgcaactgat
     3301 ggtaggcggc aagcatcggg acaactgcgg cactctcacg ttcaaagtgc ccatgctggc
     3361 tggactgcgc gtacgccata agccctctgt ccggaagcgt caggatcgtg attggcaggg
     3421 tgtagggacg tcgttccgcc atcgaaaacg gggccacgtg aagagcggtg tgtgggttgt
     3481 ctgcgaactc gagcaaccga gcaagctgca ctcccatgac tgaacggccg ccaaccggtc
     3541 gtaataggca gctctcgtcg aggatcacga agaccaacgg cgggggtgtc cggaccagag
     3601 cagcttgccg actctccact agtgcgaccc gctcgtgagc ctgctcgggc gtaatggccc
     3661 cgcgcttgac ctcctgatct tcgattgcag ctgcgtactg cggtgtctga agcagccccg
     3721 gtatcactcc gacttcgtat agacggatct ccgccgcgtg agcctcacgg gccacgtact
     3781 ccgggaaccc ttcaagcagg gcggtgtacc gcgctgcctg aatctgttgc tccaggcgtg
     3841 ccccggtccc aaacacacgg tcaagttttc tcgcaaattg ttgagttgct gctctgcgac
     3901 cagtttcaac agcggagata tgcgacccag tgcacccaac tcgttccgct agctcctctt
     3961 gagtccagcc ccgctcatcc cgcaatgtgc gtacgagcag gccaaacttc tcgcgcgggg
     4021 atcgttcagg gtgcagttgc ttgcggttcg acatacaacc gacctaactc tctcaacaat
     4081 gtgggcaagt tgagccgatc ccaactgtag gccacgctgg cgtcccttgg tagcgaatcc
     4141 gctacggaga gggatggtcg tgcctgaaga catccacgtg ggcggtctcg cctacgacac
     4201 cgtgaacaag tgcatcggcg tcgtcatgga cacatacggc ggtcgaatcg cactccgccc
     4261 gcccgccggc ggttgcgagt gggacgtacg cagagaagac gtacgaccgg ccaccgtgtt
     4321 cgaccgaatt cgagccgaac tggccgacgt gaacgcacag agcagcaaag gtatgccgtg
     4381 acctggacgt tgaaacgcgt gccgacattg cccgttctcg cgcatatgac ctgtgagtcg
     4441 gggaccccgc cctgtcgggc cgagccctcg gccggggccg gtcaactgac ggccggtgag
     4501 gtcgcttcgt gggcgcgaga gcatgtactg accaccgggc ataccgattt cgagttgctc
     4561 gtgtccagct atgtgcggtg ggagagcagc ggggacgtct cgtgaacgct cctgccaccc
     4621 ccggctacgg tgcggctgtg cttctctccg ggccgcacct ccgctggttt ccgcgtgcgg
     4681 tgttcagcag tccgtacccg agacgtgtgt tccggtggct ccgggggcag gcgctgagcc
     4741 ttgccgaccg gctcgacccg gacccggcac aggtgacgtg ggcatccgta ctgcaccccg
     4801 agccggccac ccggtacagc ggtatcgcgg acgtgccgtg ggcgctgcgc gcgtgggcgg
     4861 cgaacggtgc gaaccggaga gacgaacgcc gacttgcggc agggatcccc gtcttcatgc
     4921 tccgggcgga ccgcaccggg tcgtatgcgt tcatcgcatg gcccgtcgga cccggcacta
     4981 ccccaccgga cgatgcgctg cggtggctct cggcagccgg atacgagtgg tcacagtgac
     5041 gcgggagagc gaccacaccg tagccgtcgc cgtggctgtc atcgtccggc ccgtggacgg
     5101 gcggatcgtg ctggtgcgcc gccgtgtccc ggaaagcgag ctcgtgtggc agtttcccgg
     5161 cgggaaggtg gagccgggag aggccccgga ggccgcggcg gttcgggaga cccgggagga
     5221 aatcgggctg accgtggtcg atcgggcgcg gatcggggcc cgtatccatc cgctgaccgg
     5281 ccgccggatc gtctacatcg cctgcgacgt cgtgtccggc gtcgcccaag tcaccgcccc
     5341 tcgggagatc gcctacacgg cctggatccc gccctcccgt ctcgacacct acgcccccgg
     5401 cgtctatgag ccggtccggc agtacctcag catcaccgct cccggaagga agtcaccatg
     5461 accgcatgga attgggaaac cagggctgga gccctcgcgg accgggtgac cgacccggat
     5521 tcgcggtggc tcgctccctt ggcggtcgtg ccccgtcacc gactggtccc ccgctggtgg
     5581 gagcgggacc acgacgggcg ctgggcgctg cggatcggtt cggacgaccc tgtcgcctgg
     5641 atggacgccg cctacgggga ccagtccttg gtcaccaggg tgggcaccct ccacgcggac
     5701 cacgccgagc ccgacgacca ccccgagggg cgccccacat catcggcgac catgccgagc
     5761 ctggtcgtct cgatgctgcg gtacgcccgg ctcggagccg gtctggatgt tctcgacgtc
     5821 ggcaccgggg cgggcggtct cgccgcctat gccgccaccc ggttcggggc acggcacgtc
     5881 accagtcttg acgtagaccc ctatctcacc ggcgcggcgg cggaacggct ctccgggctc
     5941 gggctgaagc ccgggttccg cacccaggac gcgacgacgg aaatcaccgg gacgtacgac
     6001 cggatcatcg ccacggtcgg catgccaccg ggtccaggac tccggcccct gctcggcgca
     6061 ctccacccgg gcggacgcct tgtcaccgcg ctggatcgca tgggcgtgat catcaccggg
     6121 tggaaacgtg cagacggtga tgtggtggga accgtcgaac ggacgcccgc cgggttcatg
     6181 ccggcccgct cgggagccga ctacggacca acgcccgact tcgccgtagc ggaggctgct
     6241 gacggacagt ccgtcagcac cggccggtat ccggtgctcg acatcccgaa cacctgggag
     6301 ttgcggtcga tgctggaact cgccgccccc ggtgtggagg ccaccttcca cgagcagggg
     6361 cggacccgca ctgcctgtct gatccacccg gacggttcat gggcccgggc atccgccgag
     6421 tggaccgacc cgcccaccgt gcagcagagc ggcccccgaa ggctgtggga cgtcctcgaa
     6481 cacatccgga cccggctgaa catcgagggc agcctgccgt tgctcggagc acgcgtccgg
     6541 atcacaccgg atggcgtctg ccacttctcc cgaggccagt ggagagcagc catcggcgca
     6601 tgacagcccc actccgggcc accactgaaa acgccccgag cgaccgggcc taatcggtca
     6661 ctcggggctc cgaccgaaca gcttcacagg agctgaacga ccatgcgcga ctctatcgcc
     6721 cgcgccctcg catgggtgct gtccctcttc ttccccgccc ggggccgaca ccgcgccccc
     6781 aaaccgtcca caccggtcat catctgcgcc cccctcctcg cccggaccat gcccgtcccc
     6841 gagaggctca gcatcccgcc gtacacggat acgtgttccg ctcgccagga gcaggaggaa
     6901 caacggcgtc gggaacgccg taccgcactc gccttcgcgg tcatcggtat cgactaccca
     6961 tacgtcgccg agggcgttca ccaggtcacg acgggggtag ccgcatgacc cgcgagggac
     7021 tgctcaccag cgcgccggaa ccgttcaccg caccctgtgt ccactgcgga cgcaccacca
     7081 ccgcaccggt tgtcgttgga gtcaccgagc gcgccagcgg acccccgatg gtccagtacg
     7141 cgtgccccca ggacgccgca cgatacggcg ccggaccgtc acctgaggac gagatcgggt
     7201 agttcccgga cagtgaccag ctccgttcgg cctcgcaccg gacgggcctc ccgctgatcc
     7261 cctctgagcg ggtcttcggc tgcttcgtcg ttccttcggg agaacagggc cgcaccggct
     7321 gtggccaccc cggtcgggct cagtcgttct gcggcggaac cccggggcgg aactccacca
     7381 gcgggccgta ggagtagcgc ttgccgttga cgctgtcgcc ggtggcggtg ttgccggtga
     7441 ccacaacgtc cgtcaccttc gagtcaaacc cgccttcgct caccgagttg atccgcaccg
     7501 cgtgacgcgt gacgcccgcc gcgctacgcg ccagcgtcac cgtgttgccg gtgatctcca
     7561 ccccgttcag ggggttcgcg gcgacgggta ccggcggctg aaccggtgtc ttcgccgtca
     7621 tcgggctgac gtagacgccg ccgcaccccc tgttgaccgt gttcccccgg atgaccaggg
     7681 cggtggtgtt catggggccg atggcgtccc acttggcgtc gtccaccaca ttgccctcga
     7741 tcagcacgcg ggcgtgcacc tgaccggcct tctggccgcc ggtgtgcgag ccgatcagct
     7801 tggcccagga gggctgggaa ccggaggcgg ccacgtggtt gcgcaggacc cgcacgtcca
     7861 cggtcggcgt gccgtcggcc gcacccgccc aggtgttgct cgtgctcggc aggtcgagct
     7921 ggacggcctc gccctgccag agccccgcgg tcgggttctc gacccagccc ttgaagaagg
     7981 agtcctggac cacggcacgc cgtacggcgt tgagttcgac cgcgtgccac cacttgacgt
     8041 tgtagaccgt gacgccctcg atctcgatgt cctgggtgtg gatgaaggtg agggcgttca
     8101 tcggcggagc cttgtcggcg cgggcacgcg cggcccccgt gtcctcccac acgtacgcgg
     8161 agatggggtc ccactcgccg cccttgatct tgatgttgcc gggtgcggcg taccccttgg
     8221 tggtcgctgc gggcacgtga ttgatcagca ttgtggcggc cttggcgccg ctgacctcgg
     8281 gcgccgtgaa catcccctgc ccgtcgacct ggtacacggg cgtgggcgag tggtcgttcg
     8341 tcttgtccag cttgtactcc cggccggccg tcccgaactt ggcgacgaag cgggcgcccg
     8401 tcgcgtccag gagggtattg cccccgatga cgagggtgtt gaggagcgtg taggtcggta
     8461 cgcccgcgta cccggccttc acgatgatcc gccccgcgct gtcgacaccg tccggacccg
     8521 cgatcccggc cgccgcgtcg tccagcgcct tgcgcagcct gcgtacgtga gccgcctcgc
     8581 ccggcacgga cggattcacg cccgccgcgg tggcctgcgc ggccgtgtgc acacccccgg
     8641 atgcggaggc caccccgacc accgctccac cgcggagcac actccgccga ctgatccctg
     8701 tcatggtccc cgccccgtct cgtccaccgg ccgcccaatg tgaacagtct tgcgaataca
     8761 gtacggttcg gcggcgcgag cggccgccgc tgtgcgacat ccggtgagtt cccatgaagt
     8821 ccttggagaa catccaaacg accccaggac cgggccccgg cagcgcccgt cggggccggt
     8881 ggggcgggtg ccggctacgg ggtcagccgg aggttccacc cgtcggcgcc ttggccgtcg
     8941 tcatagcgaa ccaaggtggt ccggtgggtt tcgggtgcgg gtcgcccggc gtcttcccat
     9001 gcgctgagcc agccgcgcag ggcggtgagg gagggggagt cgacggtgtc ggcgaggacg
     9061 gtggcgtcct gctggatgac ggcggccgtg gtcggggtgg agtggccgag cgcccacagg
     9121 tccgggttga gtccggccat ggtcagctgt gggccggcgg tggccgccgc ccaggtccgc
     9181 caggacggcc agtcgagctt ggggccgtcg tagggctcgg tgtgcgcgtt attcagcagc
     9241 cggtccagag tggtgcgggc gccggtgtgg aggtcgtcgt cgccctcgcg ccaggcaacg
     9301 gagatccagg acggtgcggg aacacggttc tcccagtcga tccagcggcc gggcaggtcg
     9361 agatcggtct tcggagaggt ggtggcctcg atgtacccgc cgttgaacac ggcctccacg
     9421 gacggctggc agccactcac ccggatcttg gcgacgaggg tcatgttggg cacggccgcg
     9481 atgggcagcg gggcgacgat caggcctccg tcggcggtct ggtcgaccca cgcccgaggc
     9541 agcagcggcg gggtgcacca ggccacgatc cggtcgtacg gggcccggtc ggcgaacccc
     9601 gcggtgccgt cggcggtgtg gcagcggatg ttgccgacgc cgcgctggtg gtggatgagg
     9661 ccggcccacc gcaccaggta gtcgtcgatg tcgagactgg tcaccgtgcc ctgcgggccg
     9721 acaaggtgag caaggagggc gccggagtag ccggagccgg tgccgaactc ggcgacgttc
     9781 atatccgggc ggacatccag ggtggtgagt tcgcggtgga tcaccttggg gttggagcgg
     9841 tgcggggtgg caccgcggcc ttcgtggtgg gtgtagtggc gttcgggaac ggtctcggcg
     9901 gccagggcga cagggggcac gttcactcct tggagggaca ggcgggtaca tgtgtgcaac
     9961 tgctccgggc aggtgaagga cacgtccggg ggaatgttgg tcagatcctc agagcggcgt
    10021 agtggtgcca gccgccctcg gtgtactcgc caaccggtcc ggcgccgggc agttcggtcc
    10081 aggcgtggta ctcggtcggt ggcggcagga accgggcacc gaggcaccag gtcagctcct
    10141 gccgcagaaa ggccgccgcg agggcggaac cgaggctcgt ctcggcgcac gcgacacgtc
    10201 ccggccacca ccgccccgcg tgccgtaccg cggcgaccag agcgtcggcc cgtgcggggg
    10261 tgagcggccg gtgtccgagc cgcctggccc agcggacggc gcggacggtg tgccggaagg
    10321 gcagccgcag cagcaccagg gcgagcgcga tcccggcgag ggccgcgacg cgttcgggga
    10381 aggtgccggt gcgagtggtg gagtacgcct ccgtgctcgt caccgccacc acccccacca
    10441 gcaacggcgg tgcggggccg gtgctttccg ggcaagtccg gcggaagtaa gggcgttgga
    10501 gacggtccgg atgtcgtccc tggcgtggtc ggtggtcagc cggtagcggg aggcgtactc
    10561 gacggctgcc tgggcgggag tgttgcccgc cagcaggagc atgaccgccg ctgcggcggt
    10621 cggggtcagg tgggtccacc ggccagtgag ctcgtccagg atcgccccgc cctcgtcggt
    10681 gaggaccggg tgggtgccgt cacgcagttg ccacacggga gtccaccttt cgccagacgg
    10741 gcgcgggtgc cgtgtcgagc cggcggagcc agatttcggc gctggtcacc aggtgcaggg
    10801 ctccttgggc ggtcggctgt ccggccgcgg cgcgcttcag catcgcgttg acgggggctt
    10861 cggcggccag tccgagagcg gcgagccggg aggcgggacc gagcaggtcc cgcaactggc
    10921 cggcgtgacg gcgcaggccg tcgtaggcga gagcgttgaa cccgcccttc gtgacgcggg
    10981 cgaggacgaa gcccggcagg actccggtgc cggtgaacgc cgaggccagc agaggcttgt
    11041 acctccccgg tgccccgcgc tgttcggccg ggacggcgag gcaggcccgg acgacctcat
    11101 tgtccaggta gggggcggcc agctcgatcc cgtacccggc cagggcgatc tcgcgccatc
    11161 caccggtgtt cgccccgacc cgtacgaggt cctggcggtc cacccagggg gccagcagtg
    11221 tcggcgggtc cgccagttca tcggctgccc ggatgagggc gtcggcaagc cgactgcggg
    11281 cctccgggct catccagtcg gccgtggcca gcagcggcgt ccagctcacg ggccgctgag
    11341 cctgcggcac ccaggcccgc acgggaccgc gcaggtcggc agcaatctgc cgccaggcac
    11401 cggggagggc agtacggccg gccgggcggg cccggcgaag ggccgtgaag gcggaggtgt
    11461 gccgcagccg accatgtccg agcgcgtgcc gccaggcgtc gcggcgccgc cgcgtccgca
    11521 gcagatccgc cagataggac gacggcgcgg acagcagagc gtccccggcc gcccccgtca
    11581 gatggacacc gggcacggtg tgccgggccg cgaccgcgtc cagcaccgcc cgtttgatcg
    11641 ccgcggtgac cgtgtaggcg ttcggtgcat cggtgaccgg cagagcggcg aggtcgtcca
    11701 ggccctggta gtacacggtg tccggattcc cggacaccac ctggtggcgc aggccctgga
    11761 cggtggccgc ggtacgggcc gcgtaggtga ggtcgtcgtc ccgcagcctg gggtcggcga
    11821 aggtcacggc ggtcaccggt ccgctgcggg cggcgaggca ggccagggtg gtggagtcca
    11881 gacccgccag gtccgcgctg accggccggt cgtcgatcct ggctgccacc gcctcgaaga
    11941 gtgcggcccg cacgaccgga ccggcctggt gaaggtccac cggctcgtag acggccggtt
    12001 catagggcac cgtaccggcc tcctcggggc cgatcagcag cagatggccc ggcgggacgc
    12061 ggcgcacagt gcggaacagg ctccgctcgc cgaggacatc gggttgcccg aaagccagat
    12121 gggcggcgag cccgaccggg tcgaccggtg ccccgtcgag tgaggcgagc gcactggccg
    12181 aggtggccca ccaggtcccg gccgcgtccg tgcgccagta caccgggtgc tgaccggtga
    12241 ggtcgccgat caccgcaagc accgggccgc tgcgtgcaat ggtcagatag gagccgggcc
    12301 agcgggtcag cgcccgccat ttcccggccc gcaccagggc cggcgcggtc gccagctcgc
    12361 gatcgtcggc cccgcactcg ccgatgacag ccagcaccgc ccgaccctca ccagccgtcc
    12421 tgatccgggc cgagggccag ccacaagtcc atgcagcgtc caggcccggc accgcccgcc
    12481 ccccggcggg cagccggtca caggcgctgt cgccgtacca ccccgcactc cacctcatct
    12541 gtgccccttt ccgtgcacgc acttgcgtgg tttcgtagaa acgcgaaggc gccgggccgc
    12601 ccgccccgtg tcccaagcac gggaggcggg cagacccggc gccctggtgg cgccggagcc
    12661 ggtccatggc tcaaggtttc cttcccggcc ccggcggatc agaaggtcag gcgttcttgt
    12721 actcggtgtc gtccgcagtg tcgaaggtct cggtgcccag cgtcacctcg acgacagcgc
    12781 ccgcgtccag cacgacgggc gcctcgtaga ccgcagtgag ggtgtcttcc atagcgttct
    12841 ccttcactcg ccgccccgtg cgcatcctga tgagcgcaca gccgggcggg atgttccagt
    12901 ccggctgtca ctggcgttca cgctgccggg ctgtgaccga cagtcaactg gcctacacgc
    12961 accgcgagta gagtccgggc cgggccaggc cgtatatcgg gtatacgagg gcgaggaccc
    13021 catgacccag cgcatgccga accaccagct cagcgaactg atcgaggaat ccgggctgcc
    13081 gtacgacggc atcgcccgcg ccgtgagagc ggtcgcgaca gaaagcggcc agcacctggg
    13141 gaccaacaaa tcggctgtcc accactgggt ggcgggcgtc gtgccgtccg gttcgacgcc
    13201 gcagtacctg gccgaagcac tctcccgccg cctcggccgg cgcatcaccc gagaggacct
    13261 cggcctgccc tccccgggca gcggtgaaga tggcagcatc ggactgacac tcgacttcga
    13321 ccccgtcgaa atcctggccg ccatcgggaa ggctgacgtg aaccgccgta gattcctctc
    13381 cgcctccgcc tactccatgg ccgccgccgc cctgccgctg gagaccgtcc gggaaaccgc
    13441 cgcccgcgcc cgggccgccg cgagcggggc catggccgga cacgccgatg tcgcagccgt
    13501 acgggacatg gtccgcttct tcatggacat ggacgaacgc cacggcgggc agcacggacg
    13561 ctcagccttc gtccagtacc tcgtcaccga cgtactcgac ctgtgccggt cccgcttcag
    13621 cagtgaacag gcccgcgccg aggccctgtc cgtcgcctca gcaggcgccc acctggccgg
    13681 gtggaaggca tacgacagcg gcgaacaagg actcgcacag cgctactacc tgcaatcact
    13741 ggccctcgcc cgcgaatccg gtatccccgg ccaggacggc ttcgtcatgc gcaccatgtc
    13801 ccaacagggc atgaaactcc accgggccga acactgcctc gccctcgccg aaaccggctg
    13861 ggcacgcgcc cggggccggg tcgacggcca gaccgaagcc ctgttcgcca tcacgcacgc
    13921 ccacgcgctc gccaagaccg gacagaccaa tcgagccctg gccggcgcca agcaggccca
    13981 cgcctcactc acggccgggg ccgacgacca agtgcccttc tgggccctgg tctgggggcc
    14041 accggccgcc accgtccact cccgaaccgc gaaggtcttc gaaaccctcg gcgaccgccc
    14101 caatgccgcc cgccagtacg ccaccgccgc cgccagccgc cccggcgcca cctacgcgcg
    14161 gatcatcgcc ctcgacctcg tcgccgaggc cgaacagcag gccaaacagg gcagcatcga
    14221 gcaggcatgc gccacctgga cccgagccat caacaccatg gacggcgtgc ggtccgctcg
    14281 tacccgcaag gccatccgct ccctccgcgg cgaactgaac atctaccgcg cccggggtct
    14341 gcgatgcgcg accgaactcg acgagcacgc acgggccttc ctcgccaacc agcgctgacc
    14401 ggaaagctcc accgacgccg gaactcgctg tcaaaccggt cagacgcccg acacgctccc
    14461 cgcctacctc cgcgatttca cgggcgcaat cttcgggctc atggacgccc tcgggatcgg
    14521 tgaccatgag gtcttccctt cccccggtga cgcgcgatat cacagggacc ttggggcccg
    14581 atcaagtcga gtgacgtggg aggggggtgc agggtcgccc cctgggggca cccccaaagg
    14641 cagctttggg ggccgaccgg cgaacaggag ggttcgccct cgggcggtgc atcgccggcg
    14701 gcgaggaggt gagcccggag gcatccgacc cacccgcacc cgacaagacc gacgccctac
    14761 cccccgtcgc aacggtcacc catcttttga gccccgccgg cgtctgaggc gcaggagaga
    14821 cccgcacgca gcgggccgcc cacccccggg gcacggggac gcagggcccg caccatgcgg
    14881 aaaggggcat ccccgggcac ggggaccgca ccccacagcg ggaggcgacc ttgtggggag
    14941 ggggagaata gacgctggac ccgtgccgcc gcgcccattc cgcgcgcccc gccccgaagg
    15001 acgtgacatg accgaggccc ctcagggaca ccgcaagccg cgccccgccg cgctgctgtt
    15061 cgagcctgcg gaggccgtcg ccgatccgga gcacttcttc gacctggagg cgatggacga
    15121 tccgcgcgcc ctgctcgccc gggcgaccga gctgacgctg gcgttccgcg cggcgacgga
    15181 ccgggcggtg gagtatcagg cgctggcggc cgcgcagctc gcggacccgc ggcggttcga
    15241 ccggatgacg cccggggaca tcgccgagcg cgcgggctgg accgaggact acgcgcggaa
    15301 gatgatcgaa ttcggccggg gcctggcccg cgaggacggg cacgcgtagg gcagtggaca
    15361 cgcccggccg accggcccac gaggacgggc acgcgtaaag cggaggcctc gggcccgcgc
    15421 ccgcgccgcg aggacgggca cgcgcaacgc ggaggtcccg ggcgcgagcc cgcgagggcg
    15481 ggcacgcgca acgggcggga ccacccctgg cagcaagccg ccgcatggca cctggcatat
    15541 gccgggccgc aagatacccc ctcccacccc gccctgtcat cgtttcgccg acagagtgga
    15601 atcgtgcgat cactcccggt acacctggag tatgagcgcc tccacgagtg caccgttacg
    15661 caacgaccac cgcctgccgc acgcctccgc ggaggaggac cgccggcagg agagcgcgcg
    15721 aggggcggcc cggatcacgg ccgccggggc cgactggctg gccgcggcgg gagcgggccc
    15781 gcgccctcag gcggagcgct gtcccggcgc gcccgccgtg ctgtcgtgcg ggcggctctt
    15841 cgacgtggtg agcgcacccg cggtgttcgg gcggctgctg ctggaccgga tgtgggagga
    15901 gggcccgggg tcgggcccgg tcgcggccca ccggggccgg atgctggtct tcacgacgcc
    15961 gggtacggcg gcccggctgc cggccctgct gagctgggag gagtggggcg gtttcgtacc
    16021 ggcgctgatg ttccacggcc ggggggacgc cgtcacggtc cccccactgg ccgcgccggg
    16081 cgggggcgac cccggggtcg cgccgcgctg gctggtcgcg ccgggggccc ggcacccctg
    16141 gctgccgggc cccgaggtgc tgctctgggc ctgtgtacgg gccgtgaagg cggcgcgggc
    16201 ggtcgccgga gccgtccgta cgggcgcccc ggcggggccg tacggaccga tttctcctct
    16261 cccggatccg ggtgctaatg tctacgacgt cagcaggcgc cgctagctca gttggttaga
    16321 gcagctgact cttaatcagc gggtccgggg ttcgagtccc tggcggcgca cagacgggaa
    16381 aagccccctc gcgagagcga gggggctttt tcgtgcccca ggaggcccct gaggccaccg
    16441 cctcaaccgg tgctgatctt gacggtccag gcgcccgtcg ccgtacggtc ggcgacttcg
    16501 atccggatcc gctcccccga ccctccggcg agagtgaacg tttctccaac ccccagcggc
    16561 gcatccgcca gcttcggata gaccgaccgg tcccagcacg cctccgtctc cggatgggta
    16621 tcgatcacct cgaccggacc gccgccggag accgtgtcgg cgcggacccg gtagaggagg
    16681 atgccctcgg tacaggtcgt ccggtcgttg ccggccgcgc cgcgcgcctc gatcgccagg
    16741 gccgtgccgg cgccggtacg gacgacggcg agccgggtgc cgagcgcccc gcccggggcg
    16801 ggcgccgcgc ccaccggctc cagggtgatc atctcgggcc gggtgacaca gcgcacgtcc
    16861 ccggtggcga gccagcccag tttccacttg tgccaggcga acaggtcggg cgcgagtccg
    16921 aactggctgc ccatgacgtc ccagtcgccg acgtaggtgt cccagtcgcc cttgccgtcg
    16981 acgggccgct gatagaggtc cggcaggtcg aagacgtgcc cggtctcatg ggccaggacg
    17041 ttccggtccg gcgggtgctg ttcgaagacg gtcacgacgc gccgcagacc ggtgccgtcg
    17101 taggtcatgg gctgagcgaa gttgacgacc ttggtggcgt cggagtccac tccgggcgcg
    17161 tcggggtccg cgaccagata gacgatgtcg taccgggaga agtcgacggt acggtcggcc
    17221 gcgccgaggg cgtcccggag gaaggtccgc cgctgcccgg cgccccagtc ccgccgtatc
    17281 ccgtagtcgg tggacgcctt cggcatccgt acccatgcgg gctgcggatg ggcccgcaac
    17341 gcgaaccggc cgtaggaggc gcgctcgaag aaggcgctgg tggccgggaa atggtcggcg
    17401 gtcagctggg ccggagtggt gcgcggggcc gagtcgggga aagagaggaa caccatcacg
    17461 gcgtcgaggc tccggacggg ccggggatag gcggtgttcc aggtgtcgag ccccagggag
    17521 tggtgcgcgg gcgtacgggc cagcgcacag gaggcggacg aggccttggc cacggccggt
    17581 cccgcgacga gggaggtggc cgcgagggcc agcagggagg tcagcgcggc ggccgcgctg
    17641 cgggcccggc tgcgctcacc gcccgtacca cccgccccac cgttcgctcg gccaccatcg
    17701 ccccggccgc ccgcggcccc ggaaccgtcc gatccgcaca gacgcccgcc tcccacactc
    17761 ccgggtggac ccgtgggtga ctgctgacgc tccacgtcga cctccggctg cggaaaggct
    17821 gcggaatgag ggacacctcg accaccttgt gcgggtttcc agccgtacga ccacttccga
    17881 tgccccagtc gggtgaccgc tccgacaccg gcccgaaacc gagctgagac cacggggcgg
    17941 tggacacttg cggaggcacc atccggatca gcggttccgg tcaatgaagt atcagatcga
    18001 agacatgagg cgaataactt cggacacagg tacgcagaaa cgatctgtca gagactgtcg
    18061 ggacaccgcg ccacggcggt gaaggtggaa cggcccacag ggcagcctct atgatcggca
    18121 cactttcccc ggtccgtttc ctcaacgttc ctgagctttc ctcaactttc cacatctata
    18181 ccttggtttc cctgctttag gttgtttttg gatctctgcc gatcgttccc cggcggctct
    18241 cgtccgcctc ggccggtcga cggttcgtct gacgcattcc gaccacatcc acgacacaac
    18301 tgcactgcgg gagtgaaagc ggtgagcgga acccccgaag gaacagggcc cgggcgggac
    18361 tatcgggccg cgttcgacgc ggcacccctc cccatggccg tcgtcggcgc cgacggcctc
    18421 gtcaccgggg cgaacccggc cttcgccggt ctcttcggcg gggacacgac gggccgcagc
    18481 gccgaggagc tcacgggact ggcggccgac cacgacaacc ggaagaccta tcgcgacgtc
    18541 ctgcgcggcc ggcgtccccg gctctgctgc acccgccgcg tcaaacgcgc cgacggcggc
    18601 acgctgtggg cggagatcac cctcaccccg ctgaccggcc ccggcgagaa cggccgggac
    18661 ggcgacaacg gccggggcgg tgcggacagc ggggacgggc gcggcgctct cctgtgcgtc
    18721 acggacgtcg gcgaacggcg ggagctgcgc gcccgtctgc gccatctgga gatgcacgac
    18781 gcggtgacca aactgccgaa ccgggcgctg ttcttcgaac ggctcacggc cgtgctggag
    18841 tccgccgcgt acgagcgggg cgccaccggc cggatcgggc tctgctatct cgacctcgac
    18901 ggcttcaagg cggtcaacga cacgctcggg caccgcatcg gcgacaaact gctgacggcc
    18961 gtcgcggccc ggctcgccga gtgcgcggag agcgtgggcg cgtcccgggg cggcggccat
    19021 ctggtggccc ggctgggcgg cgacgaattc gccgtactcg tcgaggagtc cacgggtacg
    19081 gagcagctcg ccgatctggc cagatcggtg ctggcggcgc tgcagcgacc gttcgacctc
    19141 gacgggcagc ggctctcggt gtcggcgtcg atcggcgtgg tcgagcgggc ggcggccggg
    19201 acgtcggcga cggctctgat gcaggccgcg gataccaccc tctactgggc caaagaggac
    19261 ggaaaggccc gctggacgct cttcgacccg gagcggaacg cccaccggat gacccggcag
    19321 gcgctctcct cctcgctccg cccggctctg gagcggggcg agttcgcgct ggagtaccag
    19381 ccgctggtgg ggctggcgga cggggtcaca cacggggtgg aggcgctggt gcgctggcac
    19441 catccgcggt tcgggaccct ggcgccgaat cggttcgtcg gaatcgccga ggaggacggg
    19501 tcgatcgtcc agctgggccg ctgggtgctg cggacggcct gccggcaggc ccggcgctgg
    19561 cagctcgacc atccggggag ccggtcgctg ttcgtgagcg tcaatgtcgc cgtacggcag
    19621 gtatgggact cggatctggt ggcggacgtg gcccagaccc tggaggagac cgggctgccg
    19681 gcgcatctgc tccagctgga gctgacggag tcggcggtga tgggatcggc cgggcggccg
    19741 ttgcaggcgc tccaggcgct gagcgatatg ggggtacgga tcgcgatcga cgacttcggt
    19801 acgggctact cgaatctggc ctatctgagc cggctgccgg tctcggcgct caagctggac
    19861 ggctcgttcg tccgcggttt ccaggacgag gcgcatccga accccgccga cgagacgatc
    19921 gtggaggcgc tggtgcagtt ggcgcaccgg ctggggctga ccgtgacggc ggagtgtgtg
    19981 gagaccgcgg ggcaggcggc gcggctgcgg cggatcggct gcgacagcgg acagggctgg
    20041 ctctactcgc gggcggtgcc gccggaccgg atcgccgaac tggtcggcct caccgcgctc
    20101 ccggcctgac cgcccgcccg cccggcccgc cggggcaccg gcctcaccgg gcgcccggcg
    20161 ggacgacgcg cccggcggga acggcccacc cggcggggcg acgcgcccgg ccgaccgcac
    20221 gcccggcccg gccgtgcacc gccccgaccg cgcgcccggc gtgaaccgcg cgccccgcgg
    20281 aaatgggtac cgcccccgcc cgggatgaac atccgggcgg gggcggtgtt gtggggggaa
    20341 tacggtggtt ctgttctccg gtaccggtga cgcgttcagt gcaggtggta ccggatggtg
    20401 ctcaggggcc ggatggtgct gtggggggcg gcccctgatt ccgcggcctt ccggccgggg
    20461 tcagcaggcc ccctggtcgc gccagacacc ccactcgccg ccggtcccgg gctcgttgcc
    20521 ctgggtccac cactgggcct tccacttacg gccgttgtgg gacgcgatgg cgttggtgtt
    20581 gtagacaccg gtggcggtcc aggcttcacc gcaggccggg gtcggggtgg gcgtcggggt
    20641 gggggtggga gtcgggctcg gccggacgct ctcgccgacc gccgcgacga cgtcgttcag
    20701 cagcttggtc tgctcgtcga gcccgatgag ggagtacatc atcgcgccgc cgagaccctt
    20761 gctcttggcg taggcggccc gggcgtcgat cgcgcgcttg tccagaccgg tgaagaactc
    20821 gccgttcttg tagaagtacg cggccttggc ctcgtcgtcc cagaaggtgg tcgccgggtt
    20881 gtcgacgatt ccgccgagct ccttgtagtt ggcgataccg gccgcctggc tcagcggacg
    20941 cggggcgctg ccgccgttgg cgctctggcc gaggccgttc ttcgtcccgg cggggacgtt
    21001 cttccagccg cggtagtaca tctcgtaccc gagggtcagc ttgttcgccg ggaagccgcc
    21061 cgcgatgccg taggccgggt tgccgtcgat ccaggcgcgg accgcgttgt cgaccgagta
    21121 cttctcggtg ccgggcgcga tcgggttggt cgggtccgac ggcggggagt agagcggcga
    21181 ctggtggtag gtcgggccgg tgccgttcca ggcgccgtgc atgtcgtagg tcatgatgtt
    21241 cgcgtagtcg aggtacgcgc ccaccttgtc cgtctcgatg tgcttgatct tgtcctggcc
    21301 ggccggcatg gcggcggtca gcaggtactt cttgccgccg ttggcggtgc cgtaggcgtc
    21361 gagctgctta cggaactcgg ccagcagcag ggtgaagttg gccttgtcct cggggccgta
    21421 gtggttgccc aggtggccgc cgttggagcc ggggtactcc cagtcgatgt cgatgccgtc
    21481 gaagatcccg gcggcggtgc cggggccgcc gtagccgtcg gccttgggga cgtcaccggt
    21541 gatgtactgc ttgatgcagg aggagacgag cttcttccgg gcggcgtcgg tcttggccgc
    21601 gtcgtggaag tacttggaga acgtccagcc gcccagcgag atgttgatct tgaggtgggg
    21661 gtacttggcc ttcagcttct tgaactggtt gaagacaccg gcgatcggct ggtcccagcg
    21721 gtccgcgacc ccgtcgatgc tgtcggcggc ggagaaggtg cgctggtagt cggcgtacga
    21781 gtcgcccgcg ccgtcaccgg cgttggggtt gttgtcgtcg cccgcggcct tgttggcctg
    21841 gaagcaggtc agatcggtcg ggtggatgtt cccgaacgag tagttgatga tgtccagctt
    21901 gttcgcgatg ccccgggtgt ccaggtgctt ggggtagaag gcgtttccgt acacgctcca
    21961 ctggtcgtag tacgcgatct tcacgccggt ctgggcgggg gtggctgcgg ccgtctgctg
    22021 gggagtcgct gcattgcccg tcgcggcgaa tccggccagg acgcccgcgg cgagcgccgc
    22081 ggtcgtcatg gccgcgatca agggtttgcg ggagcgcacg taatgcctcc gaagtggggg
    22141 gaacgagggg gtgcgggccc gccggtcggc gttgggcggg ccggagcaag aaatagcgat
    22201 ccggccagcc ttcagtcaat ggtctcgacc aacctcccaa aaaaatggga ctagaccaat
    22261 tccagggaaa aagcccttgt cagagcggtg cgcaagagaa gattggcctt gtctcaccgt
    22321 tactgacgag gactttaagc gcaagataag ggcgatttaa gggctagatg atacggactt
    22381 atcggacagt tcacggatga accaccggaa agaaatcacc ggcgccgaag ggccccttca
    22441 cgcgttccgg agccccctcg gacccgccgc gcggagcggc cggcgccgcc ctcgggcggc
    22501 gctcagcctc cggtccgcgg caacccgtag gcgtccgcga cgagttcgta cgagcgcagc
    22561 cgcgccgccc cgctgtgcac attcgacgtc agcatcagct cgtccgcgcc ggtcagcttc
    22621 gccagctcgt cgagcccggc ccggacggcg tcgggcgtgc cgtggac
//
