LOCUS       NZ_CP042266            10399 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces qinzhouensis strain SSL-25 chromosome, complete genome.
ACCESSION   NZ_CP042266
VERSION     NZ_CP042266.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qinzhouensis
  ORGANISM  Streptomyces qinzhouensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8146484)
  AUTHORS   Zhu,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2019) School of Life Science, Hunan University of
            Science and Technology, He Ping Street, Xiangtan, Hunan 411201,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007856155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 04:30:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,577
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 28 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 9 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:37:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1482471
            Orig. end                         :: 1492870
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP042266.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10399
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="6"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10399
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5399](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    complement(96..109)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.44"
                     /tool="antismash"
     gene            complement(301..1386)
                     /locus_tag="FQU76_RS06085"
                     /old_locus_tag="FQU76_06085"
     CDS             complement(301..1386)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003960017.1"
                     /locus_tag="FQU76_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06085"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_146479464.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 7.6e-21, bitscore:
                     73.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDHTVLHVKGRVLVGPEDVRDELWVVGGRVTYQRPAAEAVTVPG
                     WALPGLVDAHCHVGLDAHGAVSAATSEKQALTDRDAGTLLIRDAGSAADTRWIDDRDDL
                     PKIIRAGRHIARTRRYIRNYAHEIEPADLVSYVAREAKRGDGWVKLVGDWIDREVGDLT
                     ACWPRAEVEAAIAEAHRLGARVTAHCFAEDSLRDLVEAGIDCVEHATGLTEDTIPLFAE
                     RGVAIVPTLVNIATFPALAAGGEAKFPVWSGHLRRLHERRYDTVRSAYDAGIPVFVGTD
                     AGGSLAHGLVAAEVAELVKAGIPPLDALSATTWGARAWLGRPALEEGAPADLVVYDEDP
                     RADVRALAAPRRVVLNGRITG"
     gene            1558..2667
                     /locus_tag="FQU76_RS06090"
                     /old_locus_tag="FQU76_06090"
     CDS             1558..2667
                     /NRPS_PKS="Domain: Aminotran_5 (15-294). E-value: 1.2e-29.
                     Score: 95.3. Matches aSDomain:
                     nrpspksdomains_FQU76_RS06090_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015032711.1"
                     /locus_tag="FQU76_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06090"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_146479465.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.7e-22, bitscore:
                     78.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLPPLTADRFAAIERRVAALLGTEQDVVITQGEALLPLE
                     GCIRSGARPGSTALNVVTGPYGQTFGNWLRDCGAKVVDLEVPFHTAVTAAQVEQALAGH
                     PEIDFVSLVHAEAATGNTNPVAEIGEVVRAHGALFMLDAVASVAAEPLLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSPRAWERFAANPAAPRRSYLSLLDWKERWIDGGRRTLLHAP
                     AQLEMLALEACVDRIEKDGLATVTARHSAAAAATRAGASALGGGLTPYVHEAKDAAPVA
                     TTLRTPPGVDAAALVAAALAADPSLPLVAGGGALAGEMIRVNHYGADATEDAVLSSLSA
                     LGAALAASGTAPEPVDQTAARRAALAAWS"
     aSDomain        1603..2439
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FQU76_RS06090_Aminotran_5.1"
                     /evalue="1.20E-29"
                     /label="FQU76_RS06090_Aminotran_5.1"
                     /locus_tag="FQU76_RS06090"
                     /protein_end="294"
                     /protein_start="15"
                     /score="95.3"
                     /tool="antismash"
                     /translation="FAAIERRVAALLGTEQDVVITQGEALLPLEGCIRSGARPGSTALN
                     VVTGPYGQTFGNWLRDCGAKVVDLEVPFHTAVTAAQVEQALAGHPEIDFVSLVHAEAAT
                     GNTNPVAEIGEVVRAHGALFMLDAVASVAAEPLLPDAWGVDLCVIGAQKAMGGPAGVSA
                     VSVSPRAWERFAANPAAPRRSYLSLLDWKERWIDGGRRTLLHAPAQLEMLALEACVDRI
                     EKDGLATVTARHSAAAAATRAGASALGGGLTPYVHEAKDAAPVATTLRTPPGVDAAA"
     misc_feature    2856..2871
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(2883..2899)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(2891..2905)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.51"
                     /tool="antismash"
     misc_feature    complement(2893..2906)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.16"
                     /tool="antismash"
     gene            3027..3566
                     /gene="ectA"
                     /locus_tag="FQU76_RS06095"
                     /old_locus_tag="FQU76_06095"
     CDS             3027..3566
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349983.1"
                     /locus_tag="FQU76_RS06095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06095"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_146479466.1"
                     /transl_table=11
                     /translation="MNAAQDDLVRAESRSEFTVMESPGIEDGAALWRIARDSEVLDLNS
                     SYSYLLWCRDFAATSLVARGPGGEPIAFVTGYARPDRPESLVVWQIAVDREHRGRGLAG
                     ALLDALTTRVTAELGIRRLETTVTPGNTASDRLFTAFAERRGADLERTVLFDGRLFPPG
                     AGHEPEVLYRIGPLGR"
     gene            3666..4934
                     /gene="ectB"
                     /locus_tag="FQU76_RS06100"
                     /old_locus_tag="FQU76_06100"
     CDS             3666..4934
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-365). E-value: 1.8e-69.
                     Score: 226.2. Matches aSDomain:
                     nrpspksdomains_FQU76_RS06100_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="FQU76_RS06100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06100"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_146479467.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.2e-74, bitscore:
                     250.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITPPALSVFETLESEVRSYCRSWPAVFDRARGSRLVDEDGHSY
                     LDFFAGAGSLNYGHNNPVLKRALLDYLERDGITHGLDMATTAKRTFLETFQNLVLRPRD
                     LPYKVMFPGPTGTNAVEAALKLARKVKGRESVVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFNGTVPDFLWFERLLADQGSGLNQPAAVIVETVQGEGGINVARP
                     EWLRALKELCERRDMLLIVDDIQMGCGRTGGFFSFEEAGIVPDIVTLSKSISGYGLPMS
                     LCLFLPELDIWEPGEHNGTFRGNNPAFVTAAAALRTYWADGELEKQTLDRGEQIGQALL
                     ALAGEEPEPGFGFRGRGLVWGLEFPDKRRASAVCARAFELGLLLETSGPESEVVKLLPP
                     LTVSAAELDEGLRVLARAVRETA"
     aSDomain        3750..4760
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FQU76_RS06100_Aminotran_3.1"
                     /evalue="1.80E-69"
                     /label="FQU76_RS06100_Aminotran_3.1"
                     /locus_tag="FQU76_RS06100"
                     /protein_end="365"
                     /protein_start="28"
                     /score="226.2"
                     /tool="antismash"
                     /translation="FDRARGSRLVDEDGHSYLDFFAGAGSLNYGHNNPVLKRALLDYLE
                     RDGITHGLDMATTAKRTFLETFQNLVLRPRDLPYKVMFPGPTGTNAVEAALKLARKVKG
                     RESVVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFNGTVPDFLWFER
                     LLADQGSGLNQPAAVIVETVQGEGGINVARPEWLRALKELCERRDMLLIVDDIQMGCGR
                     TGGFFSFEEAGIVPDIVTLSKSISGYGLPMSLCLFLPELDIWEPGEHNGTFRGNNPAFV
                     TAAAALRTYWADGELEKQTLDRGEQIGQALLALAGEEPEPGFGFRGRGLVWGLEFP"
     gene            5001..5399
                     /locus_tag="FQU76_RS06105"
                     /old_locus_tag="FQU76_06105"
     CDS             5001..5399
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123624.1"
                     /locus_tag="FQU76_RS06105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06105"
                     /product="ectoine synthase"
                     /protein_id="WP_146479468.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.5e-51, bitscore:
                     172.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSLDSIEDTDRHVRAASGTWESKRLVLARERVGFSLHETVLY
                     AGTETSMWYANHIEAVLCTEGTAELTNDETGEVHTIGPGTMYLLDGHERHTLRPVTDFR
                     CVCVFNPPVTGREDHDEHGVYPLITEEG"
     gene            5403..6314
                     /gene="thpD"
                     /locus_tag="FQU76_RS06110"
                     /old_locus_tag="FQU76_06110"
     CDS             5403..6314
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349980.1"
                     /locus_tag="FQU76_RS06110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06110"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_146479469.1"
                     /sec_met_domain="PhyH (E-value: 1.1e-38, bitscore: 132.2,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATATGTAVPTDLYPTRGRAEVLTPRRDPVVWSAPGAPGPLLPAQ
                     LAAYERDGFIGVEDQITDEEVALYRTEMERLIADPDVRADERSIIEPASEKVRSVFEVH
                     RISAVFAALVRDERVVGRARQILGSDVYVHQSRINVKPGFGAAGFSWHSDFETWHAEDG
                     MPTMRAVSVSIALTENRDTNGGLMIMPGSHRTFLGCAGATPEDNYKRSLRMQDAGTPSE
                     EALTRFADEHGIRLFTGRAGSATWFDCNCMHGSGDNITPYARSNVFIVFNSVENAAVEP
                     FAAPVRRPEFIGARDFTPVRPG"
     gene            complement(6401..7477)
                     /locus_tag="FQU76_RS06115"
                     /old_locus_tag="FQU76_06115"
     CDS             complement(6401..7477)
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018957689.1"
                     /locus_tag="FQU76_RS06115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06115"
                     /product="alkene reductase"
                     /protein_id="WP_146479470.1"
                     /transl_table=11
                     /translation="MTTAFDPADLAGRPLANRIVMAPMTRSRAYGPGHSPTGSMAEYYA
                     QRASAGLIVTEGIQPSVVGQGYPDTPGLHSDEQIAGWRRVTDAVHERGGTIFAQLMHVG
                     RIGHPGLLPGELRPVAPSAVRPDGQVFTKEGPQDFTTPGELSADEVRATIDDYVSAARN
                     AIAAGFDGVELHGANGYLIHQFLAPNTNRRTDEWGGTDENRIRFAVETVRAVADAIGAA
                     RVGLRISPSNPYNDIQEPAPDAVYRALVRAVEPVGIAYLHIVEATTGLRPLTRELRGEF
                     SGTLVLNPSSEGPTGHDALGLVEDGTADLLAFGALFLANPDLPSRLRTSGPYNTPDPAT
                     FFGGDERGYTDYPALATV"
     misc_feature    7508..7521
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.18"
                     /tool="antismash"
     misc_feature    7509..7524
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.85"
                     /tool="antismash"
     misc_feature    7592..7604
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     gene            7668..8252
                     /locus_tag="FQU76_RS06120"
                     /old_locus_tag="FQU76_06120"
     CDS             7668..8252
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006349978.1"
                     /locus_tag="FQU76_RS06120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06120"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_146479471.1"
                     /transl_table=11
                     /translation="MTTEAEDVTRAGTPAGAECAGAADGTGPSAPDCTGGGADYRTGPV
                     CDEKAPVSFTVSRVARLHRMASGKLLRGLGLYPGQEFVMVHLWTRGPSRQSDLIKAADL
                     DPSTVTKMLQRLEQAGHVRRCPDPADRRAVLVEATDSSGELRTAVEATLAGLEEHLLTG
                     LDEGERRELLRLLAKAELNLCREAGECNLPE"
     gene            complement(8275..9315)
                     /locus_tag="FQU76_RS06125"
                     /old_locus_tag="FQU76_06125"
     CDS             complement(8275..9315)
                     /NRPS_PKS="Domain: Aminotran_5 (15-287). E-value: 6.5e-21.
                     Score: 66.6. Matches aSDomain:
                     nrpspksdomains_FQU76_RS06125_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885285.1"
                     /locus_tag="FQU76_RS06125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_06125"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_146479472.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.7e-16, bitscore:
                     56.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METPGGAAEFALGSTYLNTASCGVLPRRAVAALDALVAELAAGRP
                     GGAGDYSTVIAVRDSFAGLMGVDAARVAVGSSLATAVGLVAQSLPPGAEVLFPEGEYTS
                     VVTPFTARGDLRPRAVPLEGLADAVRPGTALVAFSAVQSADGRIADLAAVREAAAAHGA
                     RTLADTSQSAGWLPLRASDFDYTVTVAYKFLLCLRGVSFLTVTEEAQRTLRPLFPGTFA
                     SADGELYGPARQLAPTARRFDESPAYPSFHAAVPSLELLTETGVEAVHRHTTGLARRFR
                     EGLAERGYAPVPGESAIVSVPGAADRVPDLAARGIVTAARADGLRVSFHLYNTPGHVDR
                     ILAALE"
     aSDomain        complement(8455..9270)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FQU76_RS06125_Aminotran_5.1"
                     /evalue="6.50E-21"
                     /label="FQU76_RS06125_Aminotran_5.1"
                     /locus_tag="FQU76_RS06125"
                     /protein_end="287"
                     /protein_start="15"
                     /score="66.6"
                     /tool="antismash"
                     /translation="YLNTASCGVLPRRAVAALDALVAELAAGRPGGAGDYSTVIAVRDS
                     FAGLMGVDAARVAVGSSLATAVGLVAQSLPPGAEVLFPEGEYTSVVTPFTARGDLRPRA
                     VPLEGLADAVRPGTALVAFSAVQSADGRIADLAAVREAAAAHGARTLADTSQSAGWLPL
                     RASDFDYTVTVAYKFLLCLRGVSFLTVTEEAQRTLRPLFPGTFASADGELYGPARQLAP
                     TARRFDESPAYPSFHAAVPSLELLTETGVEAVHRHTTGLARRFREGLAER"
ORIGIN
        1 ccgcggccac ggggacacgt ggccggcggc gaccgggacg cccacatctt tacgcactga
       61 gagtgaactg atggataccc ggcgtcagtt caccccaaag aggggtttcc gtgaacacat
      121 tcgattaact ggacacatgc gttccccgga acccctccgg tttcaccctc ggagcggctg
      181 cgggaggggg ccggaccgcc atcgggccgc cggccgaaag aggttcaacg accggaccgg
      241 gcacgacgtc acgcccggtc aacccggcgc cgcgcgtctc gcggggcgcc gggcgcgggg
      301 tcagccggtg atccggccgt tgaggaccac ccggcggggt gccgcgaggg cccggacgtc
      361 ggcgcgcgga tcctcgtcgt agacgacgag gtcggcgggc gcgccctcct ccagggccgg
      421 gcggcccagc caggcgcggg cgccccaggt ggtcgccgag agcgcgtcga gcggcgggat
      481 cccggccttc accagctcgg cgacctcggc cgcgaccaga ccatgggcga gcgaaccgcc
      541 cgcgtcggtg ccgacgaaga ccgggatgcc cgcgtcgtag gccgagcgga ccgtgtcgta
      601 ccgccgctcg tggagccgcc gcagatggcc ggaccagacg gggaacttgg cctcgccgcc
      661 ggccgcgagc gccgggaagg tggcgatgtt gaccagggtc ggcacgatgg cgaccccgcg
      721 ctcggcgaag agcggaatgg tgtcttcggt gaggccggtg gcgtgttcga cgcagtcgat
      781 gcccgcctcg acgagatccc ggagcgagtc ctcggcgaag cagtgcgccg tgacgcgggc
      841 accgagccga tgggcctcgg cgatggccgc ttcgacctcg gcccgtggcc agcaggcggt
      901 cagatcgccg acttcgcggt cgatccagtc gccgaccagc ttgacccagc cgtccccgcg
      961 cttcgcctcg cgggcgacgt aggagaccag atcggcgggt tcgatctcat gggcgtagtt
     1021 gcggatgtag cggcgggtgc gggcgatgtg ccggcccgcg cggatgatct tcgggaggtc
     1081 gtcccggtcg tcgatccagc gggtgtcggc cgccgagccc gcgtcccgga tcagcagggt
     1141 gcccgcgtcc cggtcggtca gagcctgctt ctcgctggtg gcggcggaca cggcgccgtg
     1201 cgcgtcgagt ccgacatggc agtgggcgtc gaccagcccg ggcagcgccc agcccggcac
     1261 ggtgaccgcc tccgccgcgg gccgctgata ggtgacgcgg ccgccgacga cccacagctc
     1321 gtcccggacg tcctccgggc cgacgagcac ccgacccttc acatgcagca ccgtgtgatc
     1381 gctcatgact gcactgtacg agggcggggt ccgcgcccac gagggtgcgg gcgggcaccc
     1441 gcgcggacgc cgaacgggcc tgcgggagag ccggtcccgg ctcggtaccc tcgtgcgtat
     1501 ggccggaaca ccccggcctg aaccgaactg tccgactgtc cgaagaaggc gcccaccgtg
     1561 acacatccgt ttctggacct ccccccgctg accgccgacc ggttcgcggc catcgagcgg
     1621 cgggtcgccg ccctgctcgg caccgaacag gacgtcgtga tcacccaggg cgaggcgctg
     1681 ctgccgctgg agggctgcat ccggtccggc gcccggcccg gttcgacggc gctgaacgtg
     1741 gtgacgggcc cgtacggcca gaccttcggc aactggctgc gggactgcgg ggcgaaggtc
     1801 gtcgatctgg aggtgccgtt ccacaccgcg gtcaccgccg cacaggtcga acaggccctg
     1861 gccgggcacc cggagatcga cttcgtctcc ctggtgcacg ccgaggcggc gaccggaaac
     1921 accaatccgg tcgcggagat cggtgaggtc gtccgggcgc acggcgccct gttcatgctg
     1981 gacgcggtgg cctcggtggc ggcggaaccg ctgctgccgg acgcctgggg cgtcgatctc
     2041 tgtgtgatcg gggcgcagaa ggcgatgggc ggcccggccg gggtgtcggc ggtatcggtg
     2101 agcccgcgcg cctgggagcg gttcgccgcg aacccggccg cgccccggcg ctcgtacctc
     2161 tcgctcctcg actggaagga gcggtggatc gacggcggcc ggcggaccct gctgcacgcg
     2221 cccgcgcagc tggagatgct ggcgctggag gcgtgtgtcg accggatcga gaaggacggg
     2281 ctcgccacgg tcaccgcccg gcactcggcg gcggccgcgg cgacccgcgc gggcgcttcg
     2341 gcgctcggcg gcggtctgac gccctatgtg cacgaggcga aggacgccgc gccggtggcg
     2401 acgacgctgc ggaccccgcc cggggtcgac gcggcggccc tggtggcggc cgcgctggcc
     2461 gccgatccct cgctgccgct ggtcgcgggc ggcggggcac tggccgggga gatgatccgg
     2521 gtcaaccact acggcgcgga cgccaccgag gacgcggtgc tgtcgtcgct gtcggcgctg
     2581 ggggccgcgc tggccgcatc gggcacggca ccggagccgg tcgaccagac ggcggcgcgc
     2641 cgcgcggctc tggccgcctg gtcctagtcc gacgccaccg cccggagcca ccgccccgga
     2701 agaatgcatt ccagggccat aaattcataa caggaccagg aaaacgggaa gcttttttgc
     2761 cgcctttacg gatggcagct tcccgttttc ttctgcccgg gttccggggc cttaaacgct
     2821 aaagttccga caggacaatc cggccacttc cggcatgtga tcgactccac agccctaccg
     2881 atttgcggct tatttgctgg acaaatgcag tcaaagcact gccatggccc agagcgagtc
     2941 gcgcccgcgc gataacacat cacccacttc gccccaaccc ctcgcgacca tgcattcatg
     3001 gaattccatc ggtaagttga atcggcatga acgccgcgca ggacgacctg gtacgagccg
     3061 aatcccgcag tgaattcacc gttatggaga gccccggtat cgaggacggg gccgcgctct
     3121 ggcgcatcgc ccgcgactcc gaggtcctgg acctcaactc ctcgtacagc tacctgctgt
     3181 ggtgccgtga cttcgccgcc acctccctgg tggcccgggg cccgggcggg gagccgatcg
     3241 ccttcgtcac cggctacgcc cggcccgacc ggcccgaatc actggtcgtc tggcagatcg
     3301 cggtggaccg cgagcaccgg ggccgcggtc tggcgggcgc gcttctcgac gccctgacca
     3361 cccgggtgac ggcggagctg ggcatccggc ggctggagac caccgtcacc cccggcaaca
     3421 ccgcgtcgga ccggctcttc acggcgttcg ccgagcgccg gggcgcggat ctggaacgca
     3481 ccgtcctctt cgacgggcgg ctgttcccgc cgggcgcggg ccatgagccc gaggtgctct
     3541 accgcatcgg gccgctcggc cgctgaacct tcggcccccg gcccgcggcc cgcggccgcc
     3601 gcacgcccgt caccgtgcgc ccgtcaccgt acgacccgat ccgtccacac ccccgggaga
     3661 gacctgtgac catcaccccg cccgccctga gcgtcttcga aaccctcgaa tcggaggtgc
     3721 gcagctactg ccggagctgg cccgcggtct tcgaccgggc ccggggcagc cgcctcgtgg
     3781 acgaggacgg ccactcctat ctcgacttct tcgccggcgc cggctccctc aactacgggc
     3841 acaacaaccc cgtactcaaa cgcgccctgc tcgactatct cgaacgggac ggcatcaccc
     3901 acggcctcga tatggcgacc acggccaaac ggaccttcct ggagaccttc cagaatctgg
     3961 tcctgcggcc gcgcgatctg ccctacaagg tgatgttccc cggccccacc ggcaccaacg
     4021 cggtggaggc ggcgctgaag ctggcccgca aggtgaaggg ccgggagtcg gtggtctcct
     4081 tcaccaacgc cttccacgga atgtcgctgg gctccctcgc ggtcaccggc aacgccttca
     4141 aacgggcggg cgcgggcatc ccgctggtcc acgggacgcc gatgcccttc gacaactact
     4201 tcaacggcac cgtccccgac ttcctctggt tcgaacggct gctggcggac cagggctccg
     4261 ggctcaacca acccgccgcc gtgatcgtgg agaccgtcca gggcgagggc gggatcaacg
     4321 tggccaggcc cgagtggctg cgcgcgctca aggagctgtg cgaacgacgc gacatgttgc
     4381 tgatcgtcga cgacatccag atgggctgcg ggcggaccgg gggcttcttc tccttcgagg
     4441 aggccggcat cgtcccggac atcgtgaccc tctccaagtc gatcagcggt tacggactgc
     4501 cgatgtcgct ctgtctgttc ctgccggagc tggacatctg ggagcccggc gagcacaacg
     4561 gcaccttccg cggcaacaat ccggccttcg tcaccgccgc cgccgcgctg cggacctact
     4621 gggccgacgg cgagctggag aagcagacgc tggaccgcgg cgagcagatc ggacaggcgc
     4681 tgctggccct ggcgggcgag gagcccgagc ccggcttcgg cttccggggc cggggactgg
     4741 tctgggggct cgaattcccg gacaaacggc gggcgtcggc ggtctgcgcc cgcgccttcg
     4801 aactggggct gctgctggag acctcgggcc ccgagagcga ggtggtgaag ctgctgccgc
     4861 cgctcaccgt ctcggccgcg gagctcgacg aggggctgcg ggtgctggcc cgcgccgtcc
     4921 gcgaaaccgc ctgacaccac acccagcacc gatatccgca tcgagaacac accgaaccga
     4981 ccacgagagg tgaccacagc gtgatcgtcc gatccctcga ctccatcgag gacaccgacc
     5041 ggcatgtgag agcggcctcc gggacctggg agagcaaacg tctggtgctg gcccgtgaac
     5101 gggtcggctt ctcgctccac gagaccgtgc tgtacgcggg caccgagacg tccatgtggt
     5161 acgccaacca catcgaggcg gtgctctgca ccgagggcac ggccgaactg accaacgacg
     5221 agaccggcga ggtccacacc atcggccccg gcacgatgta cctgctcgac gggcacgaac
     5281 ggcacaccct gcgcccggtc accgacttcc gctgtgtctg cgtcttcaac cccccggtca
     5341 ccggccggga ggaccatgac gagcacggcg tctatcccct gatcaccgag gagggctgaa
     5401 ccatggcgac cgccaccggc accgccgtac ccaccgacct ctatccgacc cgcggccggg
     5461 ccgaggtgct gaccccgcgc cgggatccgg tcgtctggtc ggcaccgggc gcgcccggac
     5521 cactgctccc cgcccagctg gcggcgtacg aacgcgacgg cttcatcggc gtcgaggatc
     5581 agatcaccga cgaggaagtc gcgctctatc gcacggagat ggagcggctg atcgccgatc
     5641 cggacgtccg cgccgacgag cgctcgatca tcgaacccgc gtcggagaag gtgcgctcgg
     5701 tcttcgaggt gcaccggatc agcgccgtct tcgccgcgct ggtgcgggac gagcgggtgg
     5761 tgggccgggc ccggcagatc ctcggctcgg acgtctacgt ccaccagtcc cggatcaatg
     5821 tgaaaccggg cttcggcgcc gccggtttct cctggcactc ggacttcgag acctggcacg
     5881 cggaggacgg gatgcccacc atgcgggcgg tctcggtatc gatcgcgctg accgagaacc
     5941 gggacaccaa cggcggactg atgatcatgc cgggttcgca ccgcaccttc ctgggctgtg
     6001 cgggcgccac cccggaggac aactacaagc gctccctgcg gatgcaggac gcggggacac
     6061 cgtcggagga ggcgctgacc cggttcgccg acgagcacgg gatcaggctc ttcaccggcc
     6121 gggcgggctc ggcgacctgg ttcgactgca actgcatgca cggctcgggc gacaacatca
     6181 cgccgtatgc ccggagcaat gtcttcatcg tcttcaacag cgtggagaac gcggcggtgg
     6241 agccgttcgc ggcgccggtg cggcggccgg agttcatcgg ggcgcgggac ttcacccccg
     6301 tacgccccgg atagtacgga tacggggggg gaggagcgcc ggtgcgcgcc cctccccctc
     6361 ctcctggccc gctcccccct cggcgggcgg ccctcgccgg tcagacggtg gccagggcgg
     6421 ggtagtcggt gtagccccgc tcgtcaccgc cgaagaaggt cgccgggtcg ggggtgttgt
     6481 acggaccgga ggtgcgcagc cgggacggca ggtccgggtt ggcgaggaag agcgcgccga
     6541 aggcgagcag atcggccgtg ccgtcctcga ccagacccag cgcgtcatgg ccggtcgggc
     6601 cctcgctgga ggggttgagc accagcgtcc cggagaactc cccgcgcagc tcccgggtga
     6661 gcggccggag cccggtggtg gcctcgacga tatgcagata cgcgatcccg accggttcca
     6721 cggcccggac gagcgcccgg tagacggcgt ccggcgcggg ctcctggatg tcgttgtacg
     6781 gattcgacgg cgagatccgc aggccgaccc gggcggcgcc gatcgcgtcc gcgaccgccc
     6841 ggacggtctc cacggcgaac cggatccggt tctcgtccgt accgccccat tcgtcggtgc
     6901 gccggttggt gttgggggcg aggaactggt ggatcagata gccgttggcg ccgtgcagct
     6961 ccaccccgtc gaagccggcg gcgatcgcgt tgcgggcggc ggagacgtag tcgtcgatgg
     7021 tggcccggac ctcatcggcg gagagttcgc ccggggtggt gaagtcctgc ggcccctcct
     7081 tggtgaagac ctgtccgtcc gggcggacgg cggagggggc gacgggacgg agctcgccgg
     7141 ggaggagacc ggggtggccg atccgcccga cgtgcatgag ctgggcgaag atcgtgccgc
     7201 cgcgttcatg gacggcgtcg gtgacccggc gccagccggc gatctgttcg tcgctgtgga
     7261 gtccgggggt gtcggggtag ccctggccga cgacggaggg ctggatgccc tcggtgacga
     7321 tcagccccgc ggaggcccgc tgcgcgtagt actcggccat ggatccggtg ggcgagtggc
     7381 cggggccgta ggcccggcta cgggtcatgg gagccatgac gatccggttg gcgagcggcc
     7441 gtccggcgag gtcggcgggg tcgaaagcgg tggtcatcga agctcccaaa gaaatacgtg
     7501 gtcgaccaat tgataatata tggccgacca atgaatccgg ctgggagcca ctgtagcgca
     7561 cttccttggc cgaccaaggt aaaattttcg agagacactg tcaccgcggg cggggagact
     7621 gacgcgcaca ccggcgaaca gcaccgacat cctgcgagga gggcccgatg acaaccgagg
     7681 ccgaagacgt gacccgggca ggaacaccgg ccggggcgga gtgcgccgga gcggccgacg
     7741 ggaccggacc ctccgcaccg gactgcaccg gaggcggtgc cgactaccgc accgggccgg
     7801 tctgcgacga gaaggccccg gtgtccttca ccgtctcccg ggtcgcccgg ctgcaccgga
     7861 tggcgagcgg caaactgctg cgcggtctcg gcctctaccc cggccaggag ttcgtcatgg
     7921 tccatctgtg gacccggggg ccgtcgcgcc agtccgatct gatcaaggcg gccgatctcg
     7981 acccgtccac ggtcaccaag atgctccagc gccttgaaca ggccgggcat gtccgccgat
     8041 gtcctgatcc ggcggaccgt cgggcggttc tcgtcgaggc gaccgattcc agtggtgaac
     8101 tgcggacggc ggtcgaggcg accctcgccg gtctggagga gcatctgctc accggtctcg
     8161 acgagggcga acgacgcgaa ctgctgcggc tgctggccaa ggccgagctg aatctgtgcc
     8221 gggaggccgg ggagtgcaac ctcccggagt gaccgctccg gtgtgcgggc ggcgctactc
     8281 cagcgcggcc aggatccggt ccacgtgccc gggtgtgttg tagagatgga acgagacccg
     8341 cagcccgtcc gcgcgggcgg cggtgacgat gccccgcgcg gcgaggtccg gcacccggtc
     8401 cgccgccccg gggacggaaa cgatcgcgga ctcccccggc accggcgcgt atccccgttc
     8461 ggcgagcccc tcgcgaaagc gccgggcgag ccccgtcgta tgccggtgga cggcctcgac
     8521 acccgtctcc gtcagcagtt ccagcgaggg gaccgcggca tggaacgagg ggtacgccgg
     8581 tgactcgtcg aagcggcgcg cggtcggcgc caactgtcgg gccgggccgt agagctcccc
     8641 gtccgccgag gcgaaggttc cggggaagag cggccgcagg gtgcgctgcg cctcctcggt
     8701 gacggtcagg aacgagaccc cgcgcagaca gagcaggaac ttgtaggcga cggtgaccgt
     8761 gtagtcgaag tcgctcgcgc gcagcggcag ccagcccgcg gactggctgg tgtcggccag
     8821 ggtccgggcg ccgtgcgcgg cggccgcctc ccgtaccgcc gcaagatcgg cgatccgtcc
     8881 gtcggcggac tgcacggccg agaacgcgac cagcgccgtg ccggggcgga cggcgtcggc
     8941 gagcccttcg agcggcacag cccgcggtct cagatcaccg cgcgccgtga acggggtgac
     9001 gacggaggtg tactcgccct cggggaagag cacctcggcg ccgggcggca gcgactgcgc
     9061 gaccagtccg acggcggtgg ccagggagct gcccacggcc acccgggcgg cgtccacgcc
     9121 catcagcccg gcgaaggaat cccgtaccgc gatcaccgtg gagtagtcgc ctgcgccgcc
     9181 gggccgcccg gcggccagct ccgccaccag ggcgtccagc gcggcgaccg cccggcgggg
     9241 cagcaccccg catgacgcgg tgttcagata cgtcgatccc agcgcgaact cggcggcacc
     9301 acccggagtc tccatatgat caccctgagc gccgggaccc gccgggtcaa ccacgggtcc
     9361 ggacggggcg cgccgtgttc gcggccgcgc cgggcggcgg gggcccggaa cgcaccggcc
     9421 gggcgcgccg tgtttgcggc cgcgccggac ggcgggggcc cggaacgcac cggctcgggt
     9481 ccggcccgac caccgcgccc gaccacggcc gcccgggccg cgccccggag acccggagcg
     9541 tggccgacgg ccccggccgg catcccgggg cgtggccgtc cggggctcgc acaaggcccg
     9601 gggccgcccg caccgaggtg ctcgcccccg ccgcccggct cggggcgccg ctcgcacaag
     9661 gcccgggccc gcccgcaccc cggagggtgc cgggccaggc agcgtacgga gcagacccgt
     9721 accccgggcc gtcccgcccc ggccacctgg tccgcgcgaa gcgcgttacg cggaggccgc
     9781 ggcctcccgg gacttccagg cctgctccag cgcctgggtg aacagttcgg cgggctggcc
     9841 gccggagact ccgtaccgcc ggtcgaagac gaagaacggc actcccttcg cccccatctc
     9901 ggacgcctcc cgctcatcgg cgcggacctc ggcggcatag gcctcgcggt cggcgacgac
     9961 cccgcgcacc tccgcttcgt ccagcccggc ctcgacggcg agcgcgatga gcaccccgtc
    10021 gtcgtagacg gaccgctcat cggcgaagtt ggcgcggtag accaggtcga gcagctcacc
    10081 ctggaggccc cggaccttcg cgagatgcag cacccggtgg atgtcgaacg tattgccgtg
    10141 gtcgcggtcg tcggtgcggt acggcaggcc ctcggcgcgg gcattcgtgg cgacgtgctc
    10201 ctccatcgcc accgcctcct cgcggctgcg cccgtagatc cgcatcagca cctcgacgac
    10261 cgtctcgacc tcgcccttgg ggcggtccgg gtccagctcg taggaccggt gcaccacctc
    10321 gacctcgccg cggtgcggga accgcgcgag gcccttctca aagcgttcct tcccgatgta
    10381 gcaccagggg caggcgatg
//
