LOCUS       NZ_CP042266            25225 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces qinzhouensis strain SSL-25 chromosome, complete genome.
ACCESSION   NZ_CP042266
VERSION     NZ_CP042266.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces qinzhouensis
  ORGANISM  Streptomyces qinzhouensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8146484)
  AUTHORS   Zhu,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-JUL-2019) School of Life Science, Hunan University of
            Science and Technology, He Ping Street, Xiangtan, Hunan 411201,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007856155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 04:30:25
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,667
            CDSs (total)                      :: 6,577
            Genes (coding)                    :: 6,475
            CDSs (with protein)               :: 6,475
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 102
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 28 of 103
            Pseudo Genes (incomplete)         :: 89 of 103
            Pseudo Genes (internal stop)      :: 9 of 103
            Pseudo Genes (multiple problems)  :: 20 of 103
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:37:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 335272
            Orig. end                         :: 360497
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP042266.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao.
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25225
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="deazapurine"
                     /region_number="3"
                     /rules="(GTP_cyclohydroI and PTPS and QueE and QueC and not
                     (dpdA1 or bTGT))"
                     /tool="antismash"
     cand_cluster    1..25225
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /kind="single"
                     /product="deazapurine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25225
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15225](-)"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15225)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(GTP_cyclohydroI and PTPS and QueE and
                     QueC and not (dpdA1 or bTGT))"
                     /neighbourhood="10000"
                     /product="deazapurine"
                     /protocluster_number="1"
     gene            complement(746..1396)
                     /locus_tag="FQU76_RS01145"
                     /old_locus_tag="FQU76_01145"
     CDS             complement(746..1396)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS01145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_01145"
                     /product="hypothetical protein"
                     /protein_id="WP_146478645.1"
                     /transl_table=11
                     /translation="MSNADSLSWFRGRVVPWVTPWSGAPALREPVVIAPNGRRGIGYAD
                     EGVHDRTYDGVLLARGRGRRPGQGDGRPLYEQLDPRRQRRATDQLLCQVCGRRPPRSPH
                     GNLWLMATAGELEGSLTTTPPVCPEPCAVLAVEQCPALARGYVAAWVRYPRPWGYQGVL
                     HAPDPADPRTVRRNGESVHLPYGDPRLPWLLADLTVTRLTGCAAVDPATGGAR"
     gene            complement(2064..2378)
                     /locus_tag="FQU76_RS01155"
                     /old_locus_tag="FQU76_01155"
     CDS             complement(2064..2378)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS01155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_01155"
                     /product="hypothetical protein"
                     /protein_id="WP_146478647.1"
                     /transl_table=11
                     /translation="MPRTGQQRDRRARLADAAAGVVPPFGCDRVGVVLHCPGGSDDAVL
                     RLRRYAEVRDWTVTAEASSWSDAEELLKGTDAQGVVTDQAGNVFSVPEMRHIYFVVALE
                     "
     misc_feature    complement(2477..2492)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.77"
                     /tool="antismash"
     gene            complement(2516..3757)
                     /locus_tag="FQU76_RS01160"
                     /old_locus_tag="FQU76_01160"
     CDS             complement(2516..3757)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953769.1"
                     /locus_tag="FQU76_RS01160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01160"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_146478648.1"
                     /transl_table=11
                     /translation="MARWSEYTTGQRIKILRGKTLRQTDLAELTGLSLPTVQQAEQDKR
                     LTLHTLLLIANALGTDTSVLLGQQGPHRGMEQDDRATIKALSRAVHDTAAGLFPDNVAA
                     PPLRTLETTAKQCWDLYWDGKYVAAGAVAGQLIAEAGARVREQPDGERAEAWRLLSDAY
                     RLASYVANLMGSRDLAYAAIGHAQFAASHADDGLSSALVMSGRAWIYLRDARLADSLAL
                     AEKAATDIEPRFSRATTGELVAYGSHINFAAVVASRIGDEELVGDYLSQSHAAGARMGR
                     EERAHGTVFGPVTASTQAVGIKVALGRTGEALGLIADINPHHEAALSGAARSRYAMDKA
                     MAQAEAKMWDASLDTLERALLDHPVWARHQALPSVIVEKVGRASTARLQRVSKLVATGP
                     EGNGFAAATAKTAL"
     gene            complement(4010..4369)
                     /locus_tag="FQU76_RS01165"
                     /old_locus_tag="FQU76_01165"
     CDS             complement(4010..4369)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006346957.1"
                     /locus_tag="FQU76_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01165"
                     /product="hypothetical protein"
                     /protein_id="WP_186767902.1"
                     /transl_table=11
                     /translation="MTVPSAPGTPPAAEVLRARYAARLPGTLEELDGPRQGEISLPLHI
                     VWSGLRTWDLDRPRSRMSLYRTVLAEGQRDDLTSYFDAGLLTSQWPVLRTLIPRAAREA
                     WENAFPQLAPRSAAE"
     gene            complement(4483..5316)
                     /locus_tag="FQU76_RS01170"
                     /old_locus_tag="FQU76_01170"
     CDS             complement(4483..5316)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014759.4"
                     /locus_tag="FQU76_RS01170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01170"
                     /product="5'-3' exonuclease H3TH domain-containing protein"
                     /protein_id="WP_146478650.1"
                     /transl_table=11
                     /translation="MTVPLLLVDGHNLLHRAWFGFAARIWNRDKTVDRTGVFGFAALLR
                     KAQAQHATGFEVFTVFDAENGSQTRLEQDPAYKGQRPAPDPGLMDSLPLVKAALDHAGV
                     RWIEQDGCEADDVIATLTTRARAAGRPVDIMSADKDYIQLLCGGEAAVRLLNTGLGLDR
                     RYTIAEHIYPRYGVHPAQWADYRALTGDPADNIAGLRGVGPKTAARLLADGRHLGAIPV
                     AELRPAWTTGWPAVLRWREMIRLDTKTDLPDELLAGLPTPPLPKAPDVLEAMNLW"
     gene            complement(5398..6693)
                     /locus_tag="FQU76_RS01175"
                     /old_locus_tag="FQU76_01175"
     CDS             complement(5398..6693)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012744.4"
                     /locus_tag="FQU76_RS01175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01175"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_146478651.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.8e-12,
                     bitscore: 45.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTDRALLYCAVNGIANNTNGVGRQTKTFLGTLQQHHAALTVQVG
                     AFTPYLAVPEPGPALWGYDPADLAHARTVVEALGGRVIPLSWDAGAPMWRPANWQALSA
                     GAARAAATLAVVHERVLVIGVDTPFAGLAHHAGTNPRVDTVLALFSTARITERPHPDPG
                     RLTWETAAITAVNQRPRVWAAGIGDFLTRHLHDTYGLRSDRVRPWPSGLHLTDPRLSPP
                     TPAEAEHTARHHGIPTDRPLITAVGRTDRTKGLDLLIEAAAPLRDRTHLAMIAVPTDDD
                     RARLLDVYRERCAALRLDATVVGHFDPELPRALAALPTSRVMAVPSLGETLANIVFETC
                     LWARGHGSVVLAPAIDGFPEQITDGHNGLLYHPTRPGALTAGLRRALGLTETERSALRE
                     AAHRRVAAERDAARHLATLLTSIWPSPPGPGR"
     gene            complement(6724..7521)
                     /locus_tag="FQU76_RS01180"
                     /old_locus_tag="FQU76_01180"
     CDS             complement(6724..7521)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036878.1"
                     /locus_tag="FQU76_RS01180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01180"
                     /product="reverse transcriptase domain-containing protein"
                     /protein_id="WP_146478652.1"
                     /transl_table=11
                     /translation="MNGPAAHSLIGQLGERGLKRAARQCMGRTGAPGGDGMSWRAFRQD
                     MPDRLAVLAASLAHGTWQPGQHRTVMFDAWGKRHTVTVPTVTDRIVHRAVRNAIEPVLA
                     HGAYPPWMYGWRPRAGRSLAVAAAARHLAAGHRWVVDIDIAAASTGVALEDAIGSVARF
                     VHDGSLLKVVRRILTALPDPLAPGSGLSPLLTNLRMTPVDHRLDGHRVVRMTDNYTIFC
                     PTRPAADQAWSHLTGLLTAHGMTVATAKSKIWRPHAEDLYAAG"
     gene            complement(7518..8621)
                     /locus_tag="FQU76_RS01185"
                     /old_locus_tag="FQU76_01185"
     CDS             complement(7518..8621)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010356716.1"
                     /locus_tag="FQU76_RS01185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01185"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_146478653.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.7e-11,
                     bitscore: 42.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIAFVLLTHNPDEPAGIERSVAALARGLHGLGHEAFILAADPPT
                     PNDGDDVLRLRSLSLPRPAVEGDLTVLLADPRPVEDEVRRTLAERRVDVVCWVDAVWGL
                     GYLAPAPAGTTSVLMVHVPRTDEPLLRSLEHAQEVVTVSPFMVRDMAEQGVDTTGWRVV
                     PNALLHDVTAPSPAEREEQRGHGPVRIVARAEPHKGIAELLRAVPTDLGRAVEIVLAEA
                     GFEYWPGMQREVIAGCQALAAGLPGVQLLAGMPWQEIPAFLAGAAVTIVSSTSPETFGN
                     VAAEALSVGTPVVGYGLGNLPDLVGTAGRMTDLEDGPGRLWADAAGLLADRAGYHAAST
                     EGPRRVTGHSSAAVASAFLDVITRARG"
     gene            complement(8618..9199)
                     /locus_tag="FQU76_RS01190"
                     /old_locus_tag="FQU76_01190"
     CDS             complement(8618..9199)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1226: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036880.1"
                     /locus_tag="FQU76_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01190"
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="WP_246150118.1"
                     /transl_table=11
                     /translation="MPAARDLSTVAAGLDPVGWIRISGGTGPAGEWHPAQTVPDLWWAA
                     APLAREGMPVTGLALLEAAQLSAEMGGRLPTSAEWEWMASRGGHRRFPWGDTEPVPGTA
                     NLRGFGPCRATPVTAHPAGRTPEGLWDVGGNVWEWTTAPWRRDRIALLRGGSYHSLVQY
                     ACCAHANDVPGHLSSPGIGIRPVRLVGGVA"
     gene            complement(9318..10004)
                     /locus_tag="FQU76_RS01195"
                     /old_locus_tag="FQU76_01195"
     CDS             complement(9318..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669029.1"
                     /locus_tag="FQU76_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01195"
                     /product="HAD family phosphatase"
                     /protein_id="WP_146478654.1"
                     /sec_met_domain="HAD_2 (E-value: 5.2e-07, bitscore: 28.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRARHAPAERRFSTVVFEFGGVLTTPMDDTARNFARDTGLPEDA
                     YRQTVAVDPAGRELYARLERGEITQERWNAEMGVRLGIDGTNLMGRALATLSPEESVVA
                     AAAAIRAGGVRTAVLSNSMGLFPHNPYGPWQLEECHDLVVLSEQHGMRKPEPGIYALTL
                     RLLGLPGTGCVFVDDNEENLAPARALGMTTVHATSPAVTVARLQQFLPHIPGLETQAEV
                     VRGGTS"
     gene            complement(10001..10609)
                     /gene="folE"
                     /locus_tag="FQU76_RS01200"
                     /old_locus_tag="FQU76_01200"
     CDS             complement(10001..10609)
                     /EC_number="3.5.4.16"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: GTP_cyclohydroI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036881.1"
                     /locus_tag="FQU76_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01200"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_146478655.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 2.5e-47,
                     bitscore: 159.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFAPPDGPARARIDQSRVADLYRQLLTELGEDPARDGLTDTPE
                     RVARWWAEFLEYNPGRTDTVFTHETAMAGGDELVVVSGITVDSLCEHHLQPMTLTVSAG
                     YRPGGQVIGLSKIARIAVARGHRLQLQERIVNGIATDLLKATGSPDVAVAATGSHACMS
                     ARGIRATGALTTSSSLHGVFAQPGPPADWFRATALGGPR"
     gene            complement(10606..11340)
                     /locus_tag="FQU76_RS01205"
                     /old_locus_tag="FQU76_01205"
     CDS             complement(10606..11340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036882.1"
                     /locus_tag="FQU76_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01205"
                     /product="WbqC family protein"
                     /protein_id="WP_146478656.1"
                     /transl_table=11
                     /translation="MNPAGSVLVVHQPAYWPWPGYFSRLLDTGQLVVLDHVQFSERGFQ
                     HRNTIAGRDGPPVRFTVPVRRRFGQPLTEVRIADEEFTGRHWRTLTAVYRRAPYWDRYA
                     DGLQTLYAQRWTHLVPLSEATIRFCLAALGIDVRLEATSSCPPAGSGTAALTNLCRRYG
                     MGVLRVGTGALGYLDPAVLARAGIRVEVATYTHPPYGPGGRRPAGLSVLDLLMHEGPRA
                     RAVLESAARTHLWNPTIRKALA"
     gene            complement(11337..12023)
                     /locus_tag="FQU76_RS01210"
                     /old_locus_tag="FQU76_01210"
     CDS             complement(11337..12023)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388629.1"
                     /locus_tag="FQU76_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01210"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_246150120.1"
                     /sec_met_domain="PIG-L (E-value: 3.5e-17, bitscore: 61.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFGLPPGSTVLVVAPHPDDETLGAGGTIARLTMAGVTVHVLVIA
                     CRSHPGSDPVVRAGELDQACTVLGVASQHIAFPGGEAATDPGSRMAEVVHLIESGPGPS
                     LRVLRPAGLLIPAAGSFHQDHRAVHDAGLAAARPSGHAPSLVLGYRGPEDTLWTAGPTA
                     RGTVAVDTGGVWETKAKALAAYTTQMRDDPHPRSVETIAALDRAAGASAGTAMAEMFVP
                     YRLVAR"
     misc_feature    complement(12009..12011)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12085..13101)
                     /locus_tag="FQU76_RS01215"
                     /old_locus_tag="FQU76_01215"
     CDS             complement(12085..13101)
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012383.4"
                     /locus_tag="FQU76_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01215"
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="WP_146478657.1"
                     /transl_table=11
                     /translation="MNTPAPRGLVVTGCSRRKAPTTRPALELYGGWCFPQLRERIAHRP
                     ELRARTLIVSARHGLLTADTPVAPYEQPLTTERVAELRREVSAGLREHLARHPAEEVLL
                     LLEPLYLRALGRMPVPVVHTVSDPAGHWPAAALVLDGWGWTALPATRAGCAGSRVFEGK
                     RIWRMSQDAFRAAAALIAANERPFAPELVVGLARGGVPLAREAARILNVPAVEVSARHN
                     VSDLIGIQSTGEVEVDEERLLAAVAGARRVLVADDICGTGATLRVVTTLLAAAGVEART
                     AVLCRNEGAAGFPLDVWVWPVADWTCFPWEAPPPDGSTLLPHPQRVHTSTAAPSFPV"
     misc_feature    complement(12661..12663)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12769..12771)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13101..13841)
                     /locus_tag="FQU76_RS01220"
                     /old_locus_tag="FQU76_01220"
     CDS             complement(13101..13841)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015983.4"
                     /locus_tag="FQU76_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01220"
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="WP_146478658.1"
                     /sec_met_domain="QueE (E-value: 1.3e-52, bitscore: 177.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.4e-08, bitscore: 32.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSSVPSIPVRGQMLPVQEIFGPVPQGEGPYSGRAAVFVRLGRC
                     NLHCPPCDSKRTWDTSLYDLEATCPPRTAEEIVSAAVTLGAGGDCLTVISGGEPLLWQR
                     TPAWSVLLTGLPGEVHMETNGTIFPTDLTREKVAHFSVSLKTGAMGAADPVKRRIRPQV
                     LDGFARLAEQGRAVFKFVAGDVNEVEEIAELVRTHELPRGRVWVMPLGDSAPAWEAAGR
                     AVVERVMEHGFHFSGRLHLTLGVR"
     gene            complement(13838..14518)
                     /locus_tag="FQU76_RS01225"
                     /old_locus_tag="FQU76_01225"
     CDS             complement(13838..14518)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: PTPS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963948.1"
                     /locus_tag="FQU76_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01225"
                     /product="6-carboxytetrahydropterin synthase"
                     /protein_id="WP_146478659.1"
                     /sec_met_domain="PTPS (E-value: 6.3e-14, bitscore: 50.6,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGVWRIGKVFRFEAARETGGSLDGHSFTAEAVLSASRLDEVGFV
                     VDFGRLASLKKYIDAVLDHQVLNGQVPDVTDTGIAAHLTAWAREHLPPDVAPVLEGVRV
                     RPGRARPGPGAATVEFGAAHRLRGLPAGHPCGRFHGHSYLITVPRTPGDQESPAPIPQR
                     LRRYVAGVLDGSVLNDVVAFNPTSELLAEHFAAQLGPAPKVGPVAVRVSETETSWAEYT
                     RSPR"
     gene            complement(14515..15225)
                     /gene="queC"
                     /locus_tag="FQU76_RS01230"
                     /old_locus_tag="FQU76_01230"
     CDS             complement(14515..15225)
                     /EC_number="6.3.4.20"
                     /GO_process="GO:0008616 - queuosine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="queC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     deazapurine: QueC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036888.1"
                     /locus_tag="FQU76_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01230"
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="WP_146478660.1"
                     /sec_met_domain="QueC (E-value: 5.8e-60, bitscore: 200.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTENSGPRAVLIASGGMDSTVTAYDLAARGIGVTLLSFDYGQRHR
                     VELEYLEKTAARMGVPHERVDLTGVGRLLAGSALTDASVEVPDGRYSDVSMRATVVANR
                     NMIMLSVAAGLAVARGAEIVAFGAHGGDHVIYPDCRPGFFERLNGALLTGNEGFLVDEF
                     RLEAPFLNGTKVDIVRRGHQLGVPFELTWSCYRGGAVHCGTCGTCSERQEAFALAGIVD
                     PTRYAAPAGAMVAR"
     misc_feature    15417..15432
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.0"
                     /tool="antismash"
     gene            15530..16837
                     /locus_tag="FQU76_RS01235"
                     /old_locus_tag="FQU76_01235"
     CDS             15530..16837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009998494.1"
                     /locus_tag="FQU76_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01235"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_146478661.1"
                     /transl_table=11
                     /translation="METTSHPLALARLAAGMTRVEFAARVRAAAARRGLRSGTDKHRVR
                     KWEVADVTPDAEAQLYIAEVLGIPARAVTPAQWPNWLPAAVVPLGPASTVPALREALRT
                     VDRRSFITAVPAAATVALAADWAHATPSALTAAARDGKPIGDDVVELLEDGARRLTGLV
                     TEQRQHMAALLDSHLTTVTDLIAQGRYPHRLGIRLHRLAASLAQTVGWWRFDHGRHHDA
                     TVYWTAALHSAHALADPDLGANTLGDLAYQAAWRRDHSTAATLLRHALSRAEHPAAQAL
                     LQLRYARALAAQGEKRETLRALDAAEYLLGVSASRPRPAFCTWLSEADLAVDSGQALLQ
                     LGDTRRAHRLIAEGQRLLPASRAKTAAVFRTYQAASDLERGEPERAAEAALASVLVARR
                     IGAPRCEQLVKDLVPRFQRYRSAEGVPELLDLARAT"
     gene            complement(17198..17326)
                     /locus_tag="FQU76_RS35060"
     CDS             complement(17198..17326)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS35060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_281292822.1"
                     /transl_table=11
                     /translation="MVGALYAATHPDSGIGDLAPLLAGVGKSLLTVPDATSPQRST"
     gene            17584..18999
                     /locus_tag="FQU76_RS01245"
                     /old_locus_tag="FQU76_01245"
     CDS             17584..18999
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746301.1"
                     /locus_tag="FQU76_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01245"
                     /product="site-specific integrase"
                     /protein_id="WP_246150883.1"
                     /transl_table=11
                     /translation="MPGDPVFVRPDGIVDSGLLDFVRSKEFRNLERESKRNYATDIRIL
                     LDFLSSRGVSWQRATEQDLADFRDWRCRAQENPQRVGGTKWNREAAAFTKLFKWGKVYP
                     LPVDVSRREDRAADSVSARVSWLTPRTWGLWSDVGLRGHTRAGVAAAGWDSRTEIRNTS
                     FVQLLLSSGLRRQEGGSLLTFELPTQHLRHGRYLHGRIAGAVTRAKNTRTFYASRDAVG
                     QVEAYVQSERAWAVQRAQAAGCYDRLTTMRLVTSVTRGIKPKVEWVDANGVVGGQELSL
                     LGWRERRSLFLEGPDGPEPAWLWLTEQGLPMEPDRWNGVFRNANLRCESVLLNEEERKV
                     DRNFRLSNVRGKSPYGTPHAARHSMALYMLILLNELFESRYGLTKADLRDFAMLFGDPW
                     WLVKTLLGHSDVETTKRHYLAPVSHLQLESILAAAETTADGQDVESLDDVFARLARETQ
                     GIQDIDSLLDVAS"
     gene            19077..20729
                     /locus_tag="FQU76_RS01250"
                     /old_locus_tag="FQU76_01250"
     CDS             19077..20729
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737572.1"
                     /locus_tag="FQU76_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01250"
                     /product="hypothetical protein"
                     /protein_id="WP_342786788.1"
                     /transl_table=11
                     /translation="MTVLNKAGHAKEFDFAQLAVAAPMQQSLAVLFAAQSARWTSHGTA
                     ESTWKKLHLFARFLSELERPPPDLDGLTAAMLKRWRTRHIGSSAGRNTLQLVRALLWRD
                     PRLADGPVAEELARRIPSSSPSKQSYDEEERERVRLAAQKQFRAALLRIRDNSELLHQW
                     RSGTLDEGSREWRIGQILDEVARTGDVPRKVGPQGRVFMRNHRLLGGRSPEVTWGRLFL
                     TRGELTALAVLLTDRFGWNLSVYDRMPTPTIAPAVAETAAKTYQVQIEKRRRGGGRWYS
                     TENITDSGASSRGRLITQALEATEHGRHLAARLAPGTDLLMVARTGRIGQEHQDLDRPM
                     PVGPLAFGVSGTDGRRWARAHQLGGSPFQRTRRTTVTREGRPLQQALGTHESVYVLPDK
                     HVQRAAQSVIADGAAEALEQARDVVFRGSLNPRRVPGHQETATADCEDATASPWLAADG
                     DCRADYLLCLACPNAHVHPGHHPRLAHLHQRLLSLRSALPEDLWNRHWQDHLLRLDDLR
                     SKLGPAAWSAALGQVDEGDHLVIDLLLEGNLAP"
     gene            20726..22876
                     /locus_tag="FQU76_RS01255"
                     /old_locus_tag="FQU76_01255"
     CDS             20726..22876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008737571.1"
                     /locus_tag="FQU76_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01255"
                     /product="integrase"
                     /protein_id="WP_146478664.1"
                     /transl_table=11
                     /translation="MTSALGLQDDPYTLPMPAGDTLVVLPQWIRPGNSHHNARFRDALW
                     PLAPLIDNPGVDLTAINWEKCPRDLHGQVKLAAWTMINGRLRSTYLQTRGARARARRSA
                     GVLQVTCREWMRLARWLHTHGITDLAECDTVAWRRYIAQRWTDRSSRTEAEMVLGRLTD
                     LWLFDRLSARPAGIDRPSWDTEGADDFLPPAGTASAGAENSTEPLDPQAIGPLLVWAIR
                     MVEDFADDILAGWAEHCRLRSLATTNRTTLSGRVALEALVLPLLHEGAQLPAMGRQGTR
                     KLARAYLAGTTGASLAQVDRLNVRHGLTSLAAQRPGPCLMQVPVTGRIKGSPWRERLDY
                     HEAAELMRHLGTAALVICLYLTGMRPQEVAALRSGCCPDPQPASDGTVQRHLIRSRHFK
                     NVTDDDGNHVSAGEQRAVPWVAVTPVVRAIRILERMVPHGELLFSATHHDFVGRRGRHG
                     ALKKHALNLRIEDFIVWVNREAQVQGLPDQSIPQDPHGALGMSRFRRTLAWHIARQPGG
                     LVALAIQYGHLRTILDARTSSGYGSRSRGGIHSVLDIETALAAADTAAHLRDRVAAGEK
                     VSGPAARRALTAAAMTPRFEGRIVPTTFAKKAARFLARDGVVLYDNPDAFLICAFKRDN
                     ALCEPDPGATAPRQYACQQGCGNAVRTDAHAQQMREKADEIDLKASLLPEKLANRLRRN
                     ADNFRKMADAHDATAQTAEALK"
     gene            22873..23295
                     /locus_tag="FQU76_RS01260"
                     /old_locus_tag="FQU76_01260"
     CDS             22873..23295
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572635.1"
                     /locus_tag="FQU76_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQU76_01260"
                     /product="hypothetical protein"
                     /protein_id="WP_146478665.1"
                     /transl_table=11
                     /translation="MNQQNQDERTFIREAMDRLLAGKATASNGSLTAAALAAEAGVHRM
                     ALYKRHTDLKNEFEERVRTETKQVPETEKQLRATIAKLKKTVASQKAEIDDLRQQVTLL
                     AMAGAVLVDRQGTPSAPELPPADAPDNVIPFRPPTT"
     gene            complement(23343..24800)
                     /locus_tag="FQU76_RS01265"
                     /old_locus_tag="FQU76_01265"
     CDS             complement(23343..24800)
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FQU76_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FQU76_01265"
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="WP_146478666.1"
                     /transl_table=11
                     /translation="MPTGNMNEVRARSWLEFRIKAATCGIEVIESEYLGSKGKHRAKCK
                     EGHELFLVPNSVQQARRITCASCRGSSSQMKKDFEEKIDDHGGEVLNPWAGTKVLYSVR
                     CAEGHESSIKPINLLKMEGICKVCNRAAREKEMLSEFKELVDTLGGQVLEEAWLGAQTP
                     HRCLCPKGHTCSPRPCSIKSGQGMCFTCSGNDPARAWESFVSRITALGAEVLEEKWLGS
                     GTPHKVRCKGGHEVAVWPSGAGKGRGICRICVGLDTKTAEAYFRNAIEELGGVAIYKAW
                     KGVNESHQVLCPKGHIASPRPNDIQQGHTMCRSCAGKDPKTAWENFKKTVAGLGGRVKE
                     KSWLGGQVPHLVQCRNGHTTTVRPAGVQQGQGICRFCAGYEWNVFYVVVNESDGHLKFG
                     ITSGDPRQRLRFHKSDGFDRLVRLLTDLPGNDAPLLEKTLLRELKAHGKQPVRGREYYL
                     IGELPLVLGLVDTHLGVGSVDAPPPAT"
ORIGIN
        1 tcgtcggcgt gggtggggtg ccagaggctg agcggcagca gcccgggccc gatgggggtg
       61 agtccgtcga agaaccgggc gatctcctcg aagccgcgcg gatgcagggg cagtccggcc
      121 tcgcgtgaca cggccacggc ccggtggacg agttgcggat cctgctcgtg ggtgaggtgg
      181 gagacgatga gcgcgctcct ggagggaaga gcgtccatga ttcggcgcac gcaggcatgg
      241 ggatggtcgt catccgcgat gtcctggagt acggcggtga ggaccactgc gaccgggcgc
      301 cggaggtcga agtgggcccg ggcctcggcg aggatcatgt ccgggtcgca caggtccagg
      361 acttccgccc ggtggcgggc gccgtcggcc cacatgcgcc agtgggcgac caccaccggg
      421 tccgcgtccg cgtacaggac acgggagcgg aagtggtggt gttcgtcggc gatggagtgg
      481 gtgtcacggg tggagtacgg cggcagcccg ggcccgatgt ccagcacctg ggcgatcccc
      541 aactcccgga ccgcgcaggt gacggcgcgc agatagaatg cccggttggc gcgggccatt
      601 tcccgtacgg gaaccccggc ggcgagcagc cgccgcacga cgacttcgtc ggcctcgtaa
      661 gcgtcccgga cctccgggtc cccgagggcg gcgtggtgga ctcgggcgct gctgaccggg
      721 cggaagctgc tctcggggta cgaggtcacc gggcaccccc ggtcgccggg tcgacggcgg
      781 cgcaacccgt gagccgggtg acggtgagat cggccagcag ccacgggaga cgcggatccc
      841 cgtacggcag atggacggat tcaccgttcc gccgaaccgt acgggggtcg gcggggtcgg
      901 gtgcatgcaa taccccctgg tagccccagg ggcgggggta ccgcacccac gcggcgacat
      961 atccgcgcgc cagggccggg cactgctcca cggccaggac ggcgcagggt tccgggcaga
     1021 cgggcggcgt ggtggtcagc gacccttcga gttcgcccgc ggtggccatg agccacaggt
     1081 tcccgtgcgg ggaccgcggg ggccgcctac cgcagacctg gcagagcagt tggtcggtgg
     1141 cacggcgctg gcggcggggg tcgagctgct cgtacagcgg tcgcccgtca ccctggcccg
     1201 ggcggcgacc ccggccgcgg gcgagcagca ccccgtcgta cgtccggtcg tggacgccct
     1261 cgtcggcgta cccgatcccc ctcctcccgt tgggtgcgat gacgacgggc tcgcgcaggg
     1321 cgggcgcacc ggaccagggc gtgacccagg ggacgacacg cccccggaac caggaaaggg
     1381 agtccgcgtt actcatgtgc ccctccgcca cgactcaact cgtccggcac gggccccggg
     1441 gtgagggcgg tcgcgtgctc ggggcagacg tactgcacaa gcccgggacc gctggcgcgc
     1501 tcgatgtaac cgacctcgac gggggcggtc gtgacgcggg cacagacacg gcagaccgcg
     1561 gtgaggggta gtgggggcgg gacgagaagg ctctccatcg tcatcacagc gaccccctgc
     1621 ggaacccgct gaggggcacg gacaagaact ctgtgacgtg ctccctcggg agcccctcgt
     1681 acgaaatcga cgatacggtc gcaggccgct ggggccgacg ctgacacata accgataagc
     1741 ccactactcg ggcgaaccag tgaacgataa ggtcactcat acggctgctc agctccttgg
     1801 aaagctggtc ggtcgagccc cggcgaaccg tgtcgcgacg gccgctgggg cgtttttgtg
     1861 gggtcaaaac ggccgaggtg gcctgacggg gcacgaaacg atgagcgacc ctgtcagcgc
     1921 gcttgccatg tggccggcag acggaggcag gggctcttcg ccacctccga ggactcagcg
     1981 gtccgttcgt cccggcgata ggaacatgtg tcggcattgc gctcagggcg cgtccatcgc
     2041 tcccttgttc tgcgcgcgca gtcctattcc agggccacca cgaagtagat gtggcgcatc
     2101 tcgggcacgc tgaacacatt gcccgcctgg tcagtgacaa ctccctgggc atccgtgccc
     2161 ttcagaagct cctcggcgtc actccatgac gacgcttcgg cggtaacggt ccagtctctt
     2221 acttccgcgt acctgcgcag ccggagcacc gcgtcgtccg acccgccggg gcaatgcaga
     2281 acgacaccca cacggtcgca cccgaagggc gggacaacac ccgctgctgc gtccgcaaga
     2341 cgggcccggc ggtctcgctg ctgtccggtt cgaggcatga agcgacgatc ccgcacctat
     2401 gagtacctgt gaagaaagcc ctcgtactat ccggatgatt cgtcaacttg ccatgtgcac
     2461 gggcgatacg agtgcatcgg acaggaatcc gacgcactca tacgccacgt acgagtcaca
     2521 aagccgtctt ggcagtcgcc gcagcgaatc cgtttccttc cggtcctgtc gcaaccagct
     2581 tggaaacgcg ctggagccga gcggtcgagg ctcggcctac cttctccacg atgacggagg
     2641 gaagggcctg gtgccgggcc caaaccgggt ggtcgaggag cgcccgctcc aaagtgtcca
     2701 gggacgcgtc ccacatcttc gcctcggcct gcgccatcgc cttgtccatg gcgtaccggc
     2761 tacgcgcggc cccggagagt gctgcctcgt ggtgcggatt aatgtcggca atgagcccga
     2821 gggcctcgcc agtccggccg agagccacct tgattccgac tgcctgggta ctcgccgtca
     2881 ccgggccgaa gactgtgcca tgggcccgct cctcgcgccc catccgagca ccggcggcat
     2941 gcgactggct caggtagtcc ccgaccagct cttcgtcccc aatgcgcgac gcgacaacgg
     3001 cggcgaagtt gatgtgcgat ccgtaggcga ccaactcgcc cgtggtagct cgggagaacc
     3061 tgggctcgat atcggtagct gccttctccg cgagcgccag ggaatccgcc aaccgagcgt
     3121 ccctcaggta gatccacgcc cgtccggaca tcacgagagc gctgctcagg ccatcatcag
     3181 catgggaggc ggcgaattgc gcatgcccaa tggcagcgta ggcaagatcc cgtgacccca
     3241 tgagattcgc cacataggaa gccagtcggt acgcgtccga gagaagcctc catgcctccg
     3301 cacgctcacc atcgggctgc tcccgcaccc gtgctcctgc ttccgcaatg agctgaccgg
     3361 ccacagctcc ggcagccacg tacttcccgt cccagtagag gtcccagcat tgcttggcgg
     3421 ttgtttccag cgtacggagc ggcggcgctg caacgttgtc ggggaagagg ccggcagcgg
     3481 tgtcgtgcac cgcccgagag agggccttga tcgttgcacg atcatcctgc tccatccccc
     3541 ggtggggccc ctgttggccg aggagcaccg aggtatccgt ccccagggca ttggcaatca
     3601 ggagaagagt gtgcagagtc aggcgcttgt cctgttcggc ctgctgcact gtgggcagtg
     3661 acagccccgt caactcggcg agatcggtct gtcggagagt ctttcctcga aggatcttga
     3721 tgcgctgacc ggtggtgtac tcactccaac gcgccatacc agtctcctga ttctcagtcg
     3781 tcccccggga acggtacccg tggtatctgc gcctgagtac aagaatgacc ccggtccggg
     3841 gttccggtgg agggcccggg cggtagtccc cgcctgcggg gagcacgcga ggacgtacgc
     3901 gaggtccttg acccggacgg gaccatcccc gcgcctgcgg ggagcacact ccctgacctg
     3961 ggtctttccc agccgccaca cgccagcctg cagtggaggc cgctcaggtt cactcggccg
     4021 ccgaccgggg ggcgagttgc gggaaggcgt tctcccacgc ctcgcgggcg gcccgcggga
     4081 tcagagtgcg caggacgggc cactgggatg tgagcaggcc ggcgtcaaag taggaggtga
     4141 gatcgtcgcg ctggccctca gccaggactg tgcggtagag gctcatacgc gagcggggtc
     4201 ggtccaggtc ccaggtccgc aggcccgacc agacgatgtg caggggaagg ctgatctcgc
     4261 cctgccgggg gccgtcgagt tcctccagtg tcccgggcag ccgggccgcg tagcgggcac
     4321 ggaggacctc ggcggcgggc ggagtaccgg gtgcggaggg gacggtcata ctcgccatta
     4381 tggcttccgc attgcggacg gagccgagga tacctggccg cgactgccgg acggaccgag
     4441 gccggtggta ccggccgggc ggtgcgcggt gcgggtcgga gatcaccaca ggttcatagc
     4501 ttcgaggaca tcgggcgctt tcggcagggg cggggtgggc aggccggcca ggagttcgtc
     4561 ggggaggtcc gtcttggtgt cgagccggat catctcgcgc cagcgcagca cggccggcca
     4621 cccggtggtc caggcggggc ggagctcggc cacagggatg gcccccaggt gccgcccgtc
     4681 ggcgaggagg cgggcggcgg tcttcggacc caccccccgc agcccggcga tgttgtcggc
     4741 cgggtcgccg gtcagcgccc ggtagtcggc ccactgcgcg gggtggacac catagcgagg
     4801 gtagatgtgc tcggcgatgg tgtaccggcg gtccaagccg agaccggtgt tgaggaggcg
     4861 gacggccgcc tcgcctccgc acaggagctg gatgtagtcc ttgtccgcgc tcatgatgtc
     4921 gaccggccgc ccggcggcgc gggcgcgggt ggtgagggtg gcgatcacgt cgtcggcctc
     4981 gcagccatcc tgctcgatcc accggacccc ggcgtggtcg agggccgcct tgaccagcgg
     5041 gagggagtcc atcagccccg gatcgggggc ggggcgctgc cctttgtagg cggggtcctg
     5101 ttccagacgg gtctgggagc cgttctcggc gtcgaagacg gtgaagacct cgaacccggt
     5161 ggcgtgctgg gcctgggctt tgcgcaggag ggcggcgaat ccgaacaccc cggtccggtc
     5221 gaccgtcttg tcccggttcc agatgcgtgc ggcgaagccg aaccaggcgc ggtggaggag
     5281 gttgtgtccg tcgaccaaga gaagggggac ggtcatgtgg ggcctccaga ggggtgcgtg
     5341 ctggtggggg cctgtgaccg cggcggacgg gcatgcgggg gccggacggg ggcgattcta
     5401 tcggcccggc cccggcgggg agggccagat gctggtcagc agcgtggcga ggtgccgggc
     5461 ggcgtcccgc tcggcggcca cccgccggtg ggcggcctca cggagggcgg accgctcggt
     5521 ctcggtcagg ccgagggccc ggcgcagccc ggcggtgagc gccccggggc gggtggggtg
     5581 gtagaggagg ccgttgtggc cgtcggtgat ctgttcgggg aagccgtcga tcgcgggggc
     5641 gagaacgacc gagccgtggc cgcgggccca caggcaggtt tcgaagacta tgttcgccag
     5701 ggtctcgccg aggctgggaa ccgccatgac ccgcgaggtg gggagggcgg cgagcgcgcg
     5761 gggcagctcc gggtcgaagt gcccgaccac ggtggcgtcc agccggagtg cggcgcagcg
     5821 ctcgcggtag acgtcgagaa ggcgggcgcg gtcgtcgtcg gtggggacgg cgatcatcgc
     5881 cagatgcgtc cggtcgcgca gaggcgctgc ggcttcgatg aggaggtcga ggcccttggt
     5941 gcggtcggtg cggccaacgg cggtgatgag cggacggtcg gtcgggatgc cgtgatggcg
     6001 ggcggtgtgt tcggcctcgg cgggggtggg cggactcagg cgggggtcgg tgaggtggag
     6061 accggacggc cagggccgca cccggtcgga gcgcaggccg taggtgtcgt ggaggtggcg
     6121 ggtgaggaag tcaccgattc cggcagccca cacgcggggg cgctggttga ccgcggtgat
     6181 ggcggcggtc tcccaggtga ggcggccggg gtcggggtgg gggcgttcgg tgatgcgggc
     6241 ggtggagaac agggcgagca ccgtgtcgac gcgcggattg gtgccggcgt ggtgggcgag
     6301 tccggcgaag ggtgtatcga cgccgatcac caggacccgc tcatgcacga ctgcgagcgt
     6361 tgcggcggcc cgggcggcgc cggcggacag ggcctgccag ttcgcggggc gccacatcgg
     6421 cgcgcccgcg tcccagctca gggggatgac ccggccgccg agtgcttcga cgaccgtgcg
     6481 ggcgtgggca aggtcggccg ggtcgtagcc ccacagcgcc gggcccggct cggggacggc
     6541 gaggtagggg gtgaacgcac ctacctggac ggtgagggcg gcgtggtgct gctggagggt
     6601 gccgaggaat gtcttggtct ggcggccgac gccgttggtg ttgttggcga tcccgttcac
     6661 ggcgcagtac agcagcgccc ggtcggtgcg cacgatgtga gggcctttcc tggtggtcgg
     6721 gggttatccg gcggcgtaga ggtcttccgc gtggggccgc cagatcttcg acttggccgt
     6781 ggcgacggtc atgccgtggg cggtgagcag gccggtgagg tgggaccacg cctggtcggc
     6841 ggcgggccgg gtggggcaga agatcgtgta gttgtcggtc atccgtacga cccggtggcc
     6901 gtcgagccgg tggtcgacgg gggtcatacg gaggttggtg agcagggggc tcaggccgct
     6961 gccgggggcg agcgggtccg ggagggcggt gaggatgcgc cggacgacct tcaggaggct
     7021 gccgtcgtgg acgaagcggg ccacggagcc gatcgcgtcc tccagggcga cgccggtgga
     7081 ggcggcggcg atgtcgatgt cgacgaccca ccgatgtccg gcggcgaggt ggcgggctgc
     7141 ggcggcgacc gcgagggacc gcccggccct cggccgccac ccgtacatcc acggcgggta
     7201 cgcgccgtgg gcgaggacgg gctcgatcgc gttgcggacg gcgcggtgga cgatccggtc
     7261 ggtcacggtc gggacggtga ccgtgtgccg cttgccccag gcgtcgaaca tcacggtgcg
     7321 gtgctggccc ggctgccacg ttccgtgggc cagggacgcg gcgaggacgg cgaggcggtc
     7381 gggcatgtcc tggcggaacg cccgccagga catgccgtcg ccgcccgggg ctcccgtgcg
     7441 gcccatgcac tggcgggcgg cccgcttcag cccgcgctcg cccagctgcc cgatcaggga
     7501 gtgcgcggcc gggccgttca cccgcgggcc cgggtgatca cgtcaaggaa cgcggacgcc
     7561 accgcggccg aggagtgccc cgtgacccgg cgcggccctt cggtggaggc ggcgtggtag
     7621 ccggcccgat cagcgaggag cccggcggcg tccgcccaca accggccggg gccgtcttcg
     7681 aggtcggtca tccgcccggc cgttccgacg aggtcgggca ggtttcccag cccgtagccg
     7741 acgaccgggg tgcccaccga cagggcctcg gcggcgacgt tcccgaacgt ctccgggctc
     7801 gtcgaggaga cgatggtgac cgcggccccg gccagaaacg ccggtatctc ctgccacggc
     7861 atcccagcca gcagctgtac accggggagg ccggcggcga gggcctggca tccggcgatc
     7921 acttcgcgtt gcatcccggg ccagtactcg aaccccgcct ctgccagcac gatctccacc
     7981 gccctgccca ggtcggtggg gacggcgcgg aggagttccg cgatgccctt gtgcggctcc
     8041 gcgcgggcca cgattcgcac cggcccgtgc ccgcgctgct cttcccgttc ggcgggggac
     8101 ggggctgtca cgtcgtggag gagggcgttg ggcactaccc gccagccggt ggtgtccacg
     8161 ccctgttcgg ccatatcccg gaccatgaac gggctgaccg tcacgacctc ctgggcgtgc
     8221 tccagactcc gcagcagggg ctcgtcggtg cgcgggacat ggaccatcag cacgctggtg
     8281 gtgcccgcgg gggccggggc gaggtagccg aggccccata cggcgtccac ccagcacacg
     8341 acgtccaccc gccgttcggc cagggtccgg cggacttcgt cttcgaccgg tcgggggtcg
     8401 gcgaggagga cggtgaggtc gccctccacc gcggggcgcg gcagggacag cgaccgaagg
     8461 cgtagcacgt cgtcgccgtc gttcggagtg ggcgggtcgg cggccaggat gaacgcctcg
     8521 tgtccgaggc cgtgcagacc tcgggcgagc gcggcgacgc tgcgctcgat gcccgcgggc
     8581 tcgtcggggt tgtgggtgag caggacgaag gcgatgttca cgcgactcct ccaacgaggc
     8641 ggacggggcg gatgccgatg ccgggcgagg acagatggcc ggggacgtcg ttggcgtggg
     8701 cgcagcaggc gtactggacc agggagtggt aggagccgcc gcgcagcagg gcgatgcggt
     8761 cgcggcgcca cggagcggtc gtccactccc acacgttgcc gccaacgtcc cacagccctt
     8821 cgggggtgcg gccggccggg tgggcggtga ccggggtggc ccggcaggga ccgaagccgc
     8881 ggaggttcgc ggtccccggt acgggttcgg tatcgcccca ggggaaacgg cggtggccac
     8941 cccgggaggc catccactcc cactccgccg aggtcggcag ccgcccgccc atctcggcgg
     9001 acagctgggc ggcctccagc agggcgagcc cggtgacggg catcccttcc cgggcgagcg
     9061 gcgccgcggc ccaccacagg tccggaaccg tctgggcggg gtgccactcg ccggccggtc
     9121 cggtgccgcc ggatatccgg atccagccca ccgggtcgag cccggccgct accgtggaga
     9181 ggtcccgggc agcaggcacg ttccctcttg gtggaaccgg cccgctcacc agcactcgcg
     9241 ggctcgccga cggtgaaaga cggccctgcc cgggcacccc acccaccccc cgtccgctgg
     9301 cgggggcggt cgtccggtca tgacgtccca ccgcgcacca cctccgcctg cgtctccagg
     9361 ccggggatgt gggggaggaa ctgttggagc cgggcgaccg tgacagcggg ggaggtggcg
     9421 tggaccgtgg tcatgcccag cgcccgggcg ggcgccaggt tctcctcgtt gtcgtcgacg
     9481 aacacacacc ccgttcccgg gaggccaagc aggcgcaggg tgagcgcgta gatcccgggc
     9541 tccggtttgc gcatcccgtg ctgttcggac aggacgacca ggtcgtggca ctcctccagc
     9601 tgccacggac cgtacgggtt gtgcgggaag aggcccatgg agttcgacag caccgccgtg
     9661 cgcaccccgc ccgcccggat cgccgccgct gcggcaacaa cggattcctc cgggctgagg
     9721 gtcgccagcg ctcggcccat cagattcgtg ccgtcgatcc cgagccggac gcccatctcc
     9781 gcgttccacc gctcctgggt gatctcgccc cgctccaggc gcgcgtacag ttcccgcccg
     9841 gccgggtcga cggcgaccgt ctgccggtac gcgtcctccg gaagtccggt atcgcgggcg
     9901 aagttgcggg cggtgtcgtc catgggggtc gtcagcaccc cgccgaattc gaagaccacc
     9961 gtggagaacc gccgctccgc cggggcatgt cgggcccggg tcatcggggg ccgccgaggg
    10021 cggtggcgcg gaaccagtcg gccggcgggc cgggctgggc gaagacgccg tgcaggctgg
    10081 aagaggtggt gagggcgccg gtggcgcgga tgccgcgggc gctcatgcac gcgtggctgc
    10141 cggtcgcggc gaccgccaca tcgggcgagc cggtcgcctt cagcaggtcg gtggcgatgc
    10201 cgttcacgat ccgctcctgc aactggagcc ggtggccgcg cgcgacggcg atccgcgcga
    10261 tcttcgacag cccgatcacc tgcccgcccg gccggtaccc ggcgctcacc gtgagggtca
    10321 tgggctgcag gtggtgctcg cacagggagt ccacggtgat cccggacacg accaccaact
    10381 cgtccccgcc ggccatggcc gtctcgtggg tgaagacggt gtcggtgcgg cccgggttgt
    10441 actccaggaa ctccgcccac cagcgggcca cccgctccgg agtgtcggtg aggccgtcgc
    10501 gggcggggtc ctcgccgagc tcggtcagca actggcggta gaggtcggcg acgcgcgact
    10561 ggtcgatccg agcccgagcc gggccgtcgg ggggtgcgaa ggtcgtcatg ccagggcctt
    10621 ccggatagtc gggttccaca ggtgggtgcg ggcggcggac tcaaggacgg cgcgggcgcg
    10681 ggggccttcg tgcatcagga ggtccagcac cgacagaccg gccggacgcc gcccgcccgg
    10741 cccgtacggg ggatgggtgt aggtggcgac ctcgacccgg atccccgccc tggcgagcac
    10801 ggcggggtcg aggtagccca gcgcgccggt gcccacccgc aacaccccca tcccgtaccg
    10861 ccggcacagg ttggtcagcg ccgccgttcc cgaaccggcc ggcggacacg agctcgtcgc
    10921 ctccagacgg acgtcgatgc cgagggcggc gaggcagaag cggatggtcg cctcgctgag
    10981 cgggaccagg tgcgtccagc gttgcgcgta cagggtctgg agtccgtcgg cgtaccgatc
    11041 ccagtacggc gcccgcctgt acacggctgt gagggtgcgc caatggcgtc cggtgaactc
    11101 ctcgtcggcg atccggacct cggtcagcgg ctggccgaag cggcgccgca cggggacggt
    11161 gaaccggacc ggtggtccgt cgcgtccggc gatcgtgttg cggtgctgga agccccgctc
    11221 ggagaactgg acatggtcca gcaccaccag ctgtccggta tcgaggagcc gggagaagta
    11281 gcccggccag ggccagtacg cgggctgatg caccaccaga accgaacctg ccgggttcat
    11341 cgggccacca gccggtacgg gacgaacatc tcggccatgg cggtgccggc cgacgccccg
    11401 gccgcccggt ccagggcggc gatcgtctcc acgctccggg ggtgcggatc gtcgcgcatc
    11461 tgggtggtat aggcggccag ggccttcgcc ttcgtctccc acaccccgcc ggtgtccacc
    11521 gccaccgtcc cccgcgccgt gggtccggcg gtccagaggg tgtcctcggg accgcggtag
    11581 ccgagcacca gggagggggc gtgcccggag ggacgggcgg cggcgagacc ggcgtcgtgg
    11641 acggcccggt ggtcctgatg gaatgaacct gcggccggga tcagcagccc ggccgggcgc
    11701 agcacgcgca ggctcggccc ggggccggac tcgatcaggt gtaccacctc ggccatccgg
    11761 ctgcccgggt cggtcgccgc ctcgccaccg gggaaggcga tgtgttggga ggcgacgccg
    11821 agcacggtgc acgcctggtc gagttcgccg gcgcgcacca cggggtcgct gcccgggtgg
    11881 ctgcggcagg cgatcaccaa gacatggacc gtgacaccgg ccatcgtgag gcgggcgatc
    11941 gtaccgcccg cgccgagggt ctcgtcgtcc ggatgcggcg cgacgaccag caccgtactg
    12001 cctggcggta atccgaagat catcgaatgg tctcctcttg ccgtgggagg gatacgggcc
    12061 gaaccggggc acgtgcgccc cgtgtcacac cgggaaggac ggcgcggcgg tggaggtgtg
    12121 gacgcgctgg gggtgcggga gcagcgtcga gccgtccggg ggcggggcct cccaggggaa
    12181 gcaggtccag tccgcgaccg gccacaccca cacatccagc ggaaagccgg ctgcgccctc
    12241 gttgcggcat agcaccgctg tccgggcctc gacgcccgcg gcggcgagaa gcgtggtgac
    12301 gacccgcagc gtggcgccgg tgccgcagat gtcgtcagcg accagcaccc ggcgcgcccc
    12361 ggcgaccgcc gccagcaacc gctcctcgtc gacctcgacc tctccggtgg actggatgcc
    12421 gatcagatcc gagacgttgt gccgtgccga gacctcgaca gccggaacat tgaggatccg
    12481 ggccgcctca cgggcgagcg ggaccccgcc gcgggccagc ccgacgacga gttcgggggc
    12541 gaagggccgc tcgttcgcgg cgatgagcgc cgccgccgcg cggaaggcgt cctggctcat
    12601 ccgccagatc cgcttcccct cgaagacccg gctccccgca cagcccgccc gcgtggccgg
    12661 taaggcggtc cagccccacc cgtccagcac cagggccgcg gccggccagt gcccggccgg
    12721 gtcgctcacc gtgtgcacga ccggcaccgg catccgtccc agcgcccgta agtacagggg
    12781 ctccaggagc agcagcactt cctcggccgg gtgccgggcc aggtgctcgc gcagcccggc
    12841 cgatacctcc cgccgcaact ccgcgacgcg ctccgtggtc agcggctgct cgtacggtgc
    12901 gacgggggtg tctgcggtga gaagcccgtg tcgtgcggac acgatcagcg ttcgtgctcg
    12961 cagttcgggg cggtgggcaa tccgttcccg cagttgcggg aagcaccacc ccccgtacag
    13021 ttccagcgcg ggccgggtgg tgggggcttt gcggcgggag cagccggtca ccaccaggcc
    13081 gcgcggcgcg ggggtgttca tcagcgcacc cccagggtga ggtggagccg gccggagaag
    13141 tggaagccgt gttccatcac ccgctccacc actgcccgtc cggccgcctc ccatgccggg
    13201 gcgctgtcgc cgagcggcat cacccacacc cgcccccgcg gaagctcgtg ggtccgcacg
    13261 agctcggcga tctcctcgac ctcgttcaca tcgcccgcga cgaacttgaa gaccgcgcgg
    13321 ccctgttcgg cgaggcgggc gaagccgtcg aggacctgag gccggatccg gcgctttacc
    13381 gggtcggccg cgcccatggc cccggtcttc agggacacgc tgaagtgcgc gaccttctcc
    13441 cgggtcaggt cggtggggaa gatggtgccg ttggtctcca tatggacctc gcccggcaat
    13501 ccggtgagga gcaccgacca tgcgggggtg cgctgccaca gcagtggctc gcccccgctg
    13561 atcaccgtga ggcagtcgcc gcccgcaccg agcgtcacgg cggccgagac gatctcctcg
    13621 gccgtgcgcg gcgggcaggt ggcctcgagg tcgtaaagac tggtgtccca ggtccgcttc
    13681 gagtcgcacg gcgggcagtg cagattgcac cggcccagcc gcacgaacac tgccgcccgg
    13741 ccgctgtagg ggccctcacc ctgggggacc ggaccgaaga tctcctgcac cggaagcatc
    13801 tgcccccgga ccggtatcga aggaacagag ctgctgctca tcggggactc cgggtgtact
    13861 cggcccagct cgtttccgtc tccgacaccc gcaccgcgac cgggccgacc ttcggggccg
    13921 ggccgagctg ggcggcaaag tgctcggcga ggagctctga ggtggggttg aaggcgacca
    13981 cgtcgttgag gaccgacccg tccagcaccc cggcgacgta cctccgcaac cgctgaggga
    14041 tgggcgcagg actctcctgg tcccccgggg tgcgggggac ggtgatgaga taggagtggc
    14101 cgtggaacct tccgcacggg tgcccggcag gcaggccgcg cagccggtgc gccgccccga
    14161 actccaccgt cgcggctccg gggcccgggc gggcccggcc gggccgcacc cgcacgccct
    14221 ccagcaccgg ggcgacgtcc gggggcagat gctcccgtgc ccaggcggtg agatgcgcgg
    14281 cgatccctgt gtcggtgaca tccgggacct ggccgttgag gacctggtga tcgaggaccg
    14341 cgtcgatgta tttcttcagc gaggccagcc gcccgaagtc gacgacgaac cccacctcat
    14401 ccagcctgct cgcggacagg accgcctccg cggtgaagga gtgcccgtcc aggctccccc
    14461 cggtctcgcg ggccgcctcg aaacggaaga ccttcccgat ccgccacacc ccgctcaccg
    14521 ggccaccatt gcgccggccg gggccgcgta gcgcgtgggg tccacgatgc cggcgagggc
    14581 gaacgcctcc tggcgctcac tgcacgtccc gcacgtcccg cagtgcaccg ccccgccccg
    14641 ataacaggac caggtcagct cgaacggcac gccgagctgg tgcccgcggc ggacgatgtc
    14701 caccttcgtc ccgttcagga acggcgcctc cagccggaac tcgtccacga ggaaaccctc
    14761 gtttcccgtc agcagggccc cgttcaaccg ctcgaagaac cccgggcggc agtcggggta
    14821 gatgacgtgg tccccgccgt gcgcaccgaa cgccacgatc tcggccccgc gggcgacggc
    14881 cagccccgcg gcgaccgaca gcatgatcat gttgcggttg gcgacgaccg tcgccctcat
    14941 cgatacatcg ctgtagcggc cgtccggcac ctcgaccgaa gcgtccgtga gcgcggaccc
    15001 ggccagcagc cgtccaacgc cggtcagatc gacgcgctcg tgcggcacgc ccatgcgtgc
    15061 ggcggtcttc tccaggtact ccagttcgac gcggtggcgc tgcccgtagt cgaaggacag
    15121 cagcgtcacc ccgatcccgc gggcggcgag gtcgtaggcg gtcactgtgc tgtccatgcc
    15181 gccggaggcg atgagcacgg cccgcgggcc gctgttctcg gtcatccagg tctccttcac
    15241 cgtgtcggat ggtcctgtcg gtcgtcagcg catgccgggg ccgctgacgg caccgtcaag
    15301 gtgtgtgtga ggaaggggag gtcccgctgc cgcacccggg cacagggtcc gggcacgtgc
    15361 gggtaggcca gatgcgtgcg atcgggcgga ggcgtgttcg agcccgtccg gaggagtcga
    15421 gtgtgcgttc aactcgggcc gacggtccat gagttggcgg gggtcccgtc gggggtcccg
    15481 tcaggccgga accgttcccg gccgcgtccg ccggtgggac gatgcgagcg tggagaccac
    15541 cagtcacccg ctcgcgctgg cccgcctcgc cgccggcatg acccgggtcg aattcgcggc
    15601 ccgcgtccgg gccgccgccg cccggcgggg cctgcgctca ggcaccgaca agcaccgggt
    15661 ccgcaagtgg gaagtcgcgg acgtcacccc cgacgcggag gcccagctgt acatcgccga
    15721 agtcctcggc atcccggccc gcgcggtcac cccggcccag tggcccaact ggctcccggc
    15781 ggccgtggtc cccctcggcc cggccagtac cgttcccgct ctgcgagagg cattgagaac
    15841 tgtggaccgc cgatccttca tcaccgccgt cccggccgcc gccaccgtcg ccctcgccgc
    15901 tgactgggcc cacgccacgc ccagcgccct gaccgccgct gcccgtgacg gcaaacccat
    15961 cggggatgac gttgtcgaac tgctggagga cggggctcgc cgcctcaccg gtctggtcac
    16021 cgagcagcgc cagcacatgg cagccctgct ggactcccac ctcaccaccg tgaccgacct
    16081 catcgcccag ggccgatacc cccaccggct cggaatccgc ctccaccggc tcgccgcctc
    16141 cctggcgcag accgtcggct ggtggcgctt cgaccacggc cgccaccacg acgccaccgt
    16201 ctactggacc gcagccctcc acagcgccca cgccctcgcg gatccggatc tcggcgccaa
    16261 cacgctgggc gacctcgcct accaagcggc ctggcgccgc gaccacagca ccgccgccac
    16321 cctcctgcgc cacgccctca gccgcgccga acaccccgct gcccaggcac tgctccagct
    16381 ccggtacgct cgcgcgctgg ccgcccaggg agagaagcgg gaaaccctcc gggccctgga
    16441 cgccgccgag tacctcctcg gcgtctcagc ctcccggccc cggcccgcgt tctgcacctg
    16501 gctctccgaa gccgaccttg cggtcgattc cggccaggca ctcctgcaac tcggcgacac
    16561 ccgccgcgcg caccggctca tcgccgaagg acagcgcctc ctgcccgcca gccgcgcgaa
    16621 aaccgcggcc gtcttccgta cctaccaggc cgcatccgac ctggaacgcg gcgaaccgga
    16681 acgcgccgcg gaagccgccc tcgcatccgt cctcgtcgcc cgccggatcg gcgcgccgcg
    16741 ttgcgaacag ctcgtcaagg acctcgtccc ccgcttccag cgttaccgca gcgccgaggg
    16801 tgtccccgaa ctcctcgacc tcgcccgcgc tacctgactc caccgccgtt cgccggcccg
    16861 tgcggcgacg ggtgaccagc tcgcacctgt cgcgcccgcg ccacgggccc gggagccatg
    16921 tccgggtggt gtccacagat ggtcctccct ctcgcggccg gggactcggc ggtatgtggc
    16981 cgccgccgtc cagcaaagcc gtgccgcaaa cgcccgggga ggcacacagg gggcacacaa
    17041 tccggcgacc ggctgcgcga cgccggagcc gggctctacg ctcggtgccc gccccctcgg
    17101 tccgcgccgg gagcaggagg gcgggcatcg gtctgggccg ctccatccag acttcggtgc
    17161 gcgcggattg ccgcccactt ccgccctacc tggggcgtca cgtcgatcgt tgcggtgacg
    17221 tggcgtccgg gacggtcagc aggctcttgc ccaccccagc cagcagcggc gcgagatcac
    17281 cgatgccgga atccgggtgc gtcgccgcgt acagcgcccc caccacccac ggctccccgg
    17341 cctccggatg gagagggccg agcgcggcgg cctggacggc gaggacggtg atcaggtggg
    17401 tgcgccggtg gtccggatgc ccggtttccc tgatgattga gcgtgttcag gcaccagggg
    17461 aggcgcaggt tgagtacgtg gcatgtggtg cgggtaccgg atccagagcg gtgggggacg
    17521 ctcccacttg gtggtgtgct gggggtacag gacctgccga cggcggtgtc ccagatccgg
    17581 ttgatgccgg gggaccctgt attcgttcga ccggacggca tagttgattc gggcctgctg
    17641 gattttgtcc gctccaagga attccggaac ctggaacggg aatccaagcg aaattacgcg
    17701 acggatattc gcattcttct tgacttcctg tcttcgcgcg gggtgtcgtg gcagcgggcg
    17761 accgagcagg atctcgcgga cttccgtgac tggcggtgcc gagctcagga gaacccccaa
    17821 cgggtcggtg gtacgaagtg gaaccgtgag gcggcggcgt tcaccaagct gttcaagtgg
    17881 ggcaaggtct atcctctgcc ggtagacgtg tctcggcgag aggaccgggc cgcagactcg
    17941 gtcagtgcgc gggtgtcgtg gctgacgccg cggacatggg gcctgtggtc ggacgtcggg
    18001 ctgcgcggcc acacccgggc tggggtggcg gcggcggggt gggattcgcg gacggagatc
    18061 cgcaacacca gtttcgtgca gcttctgctg agttcgggcc tgcgtcggca ggagggtggt
    18121 tcgctgctga cgttcgagtt gccgacccag catctgcggc acggccgcta cttgcatggc
    18181 cggatcgcgg gcgcggtgac gagggcgaag aacacccgca cgttctacgc atccagggac
    18241 gctgtcggcc aggtcgaggc gtatgtccag tcggagcggg cctgggccgt tcagcgggcc
    18301 caggctgcgg gctgctacga ccggctgacg acgatgcggc tggtcacgag cgtgacacgc
    18361 gggatcaagc cgaaggtgga atgggtggac gccaacggcg tcgtcggcgg gcaggagctg
    18421 agcctcttgg gctggcgcga gcgacggtcg ttgtttctgg aagggccgga cgggccggag
    18481 ccggcttggt tgtggctgac tgagcagggc ctgcccatgg agccggatcg ctggaacggc
    18541 gtgttcagga acgcgaacct gcgctgcgag agtgtcctgc tcaacgagga ggaacggaag
    18601 gtcgaccgga acttccggct gtcgaacgtc cgcggcaaga gcccgtacgg caccccacat
    18661 gccgccaggc attctatggc gctctacatg ctgatcctgc tgaacgagct gttcgagtcc
    18721 cggtacggtc tgacgaaggc ggacctgcgt gacttcgcca tgctgttcgg cgatccgtgg
    18781 tggttggtga agaccctcct ggggcactcc gacgtggaga ccacgaagcg gcactatctc
    18841 gcacccgttt cgcacctgca gctggagtcc atcctggcgg ccgcggagac cactgccgac
    18901 ggccaagacg tcgaaagcct ggacgacgtc ttcgcgcgcc tcgctcggga gacgcagggc
    18961 atccaggaca ttgacagcct cctcgatgtg gcttcgtgag cccccgcggg cgtcgtgctg
    19021 cccggccgcc atctgggcac cgcgccgagg ccccgctggc tcaaggcaca cttgtggtga
    19081 ccgtactgaa caaagctggc cacgcgaagg aattcgactt tgcgcagttg gccgtagccg
    19141 cgccgatgca gcagtccctg gctgtcctct tcgccgccca gtccgcccgg tggacgagtc
    19201 acggaacagc ggagagtacg tggaagaaac tgcacctgtt cgcgcggttc ctgtccgagc
    19261 tggagaggcc gccgccggac ttggacggct tgaccgcggc catgctcaag cgttggcgca
    19321 cgcggcacat cggttccagc gcggggcgga acacgctgca gctcgtccgt gccctgctct
    19381 ggcgggatcc gcgactggct gacggaccgg tggccgagga gctcgcccgg cgcattccca
    19441 gttccagtcc gagtaagcag tcgtacgacg aggaggagcg agaacgggtg cggctggccg
    19501 cgcagaagca gttccgggcg gccctgctac ggattcggga caactctgag ctgctgcatc
    19561 agtggcggtc cggcacgctc gatgagggta gccgtgagtg gcggattggg cagatcctcg
    19621 acgaggtggc ccgcactggt gacgtccctc gcaaggtcgg cccgcagggc agagtcttca
    19681 tgaggaacca ccgtctcctg ggcgggagga gtcccgaggt cacctggggg cggttgttcc
    19741 tcacccgcgg cgagctgacg gcgctggccg tcctccttac ggacaggttc ggatggaatc
    19801 tgtccgtcta tgaccgcatg cccacgccca ccattgcgcc cgcagtggca gagacagcag
    19861 ccaagaccta ccaggtccag atcgagaagc gccgccgggg tggcggacgt tggtactcaa
    19921 cggagaacat caccgactcc ggggccagct ctcgcgggcg gctgatcact caggccctgg
    19981 aagcgaccga gcacggccgc catctggccg cgcgcctggc tccaggcact gatctgctga
    20041 tggtcgcccg cacaggccgg atcggtcagg agcaccagga cctggatcgt cctatgccgg
    20101 tcggtccgct cgccttcggc gtctcgggca ccgacggcag gcggtgggcg cgggcacacc
    20161 aactgggcgg atcgccgttc cagcggacgc gcaggacgac ggtgactcgc gaaggccgcc
    20221 cgttgcagca ggctctgggg acacacgaaa gcgtctacgt cttgccggac aagcacgtcc
    20281 aacgagccgc ccagagcgtc atcgcagacg gagcggccga ggccctggaa caggcccggg
    20341 acgtcgtgtt caggggcagc ctgaatccaa ggcgagtgcc cgggcaccaa gaaacggcaa
    20401 cggccgactg cgaggacgcg acggccagtc cctggctggc cgcggacggc gactgcaggg
    20461 cggactacct actctgtttg gcctgcccca acgctcacgt tcaccctggc caccaccctc
    20521 gcctggccca tctgcaccaa cgcctcctca gtctgcgatc cgcactgccc gaggacctct
    20581 ggaacaggca ctggcaagat cacctgctcc ggctggacga cctgcgcagc aagttgggcc
    20641 cggcggcctg gagtgccgcc ctgggccagg tcgacgaggg cgaccacctc gtcattgatc
    20701 tcctgctgga agggaacctc gctccatgac cagcgccctc ggcctccagg acgaccccta
    20761 caccttgccc atgcccgcag gcgacacact cgtggtgctt cctcagtgga ttcggcccgg
    20821 caactcgcac cacaacgcgc gtttccggga cgcgctgtgg ccgctggcac cgcttatcga
    20881 caacccaggg gtggacctca ccgcgatcaa ctgggagaaa tgcccccgag acctccacgg
    20941 ccaggtgaaa ctcgccgcct ggaccatgat caacgggcga ctgcgatcca cgtatctaca
    21001 gacccgcggt gcacgggccc gagctcgccg ctccgccggc gtgcttcagg tcacctgccg
    21061 tgaatggatg cggctggccc gctggcttca cacgcatggg atcacagatc tcgctgaatg
    21121 cgacaccgtc gcatggcggc ggtacattgc ccagcgctgg acggacagaa gcagccggac
    21181 agaagccgag atggtcctcg ggcggctgac cgacctgtgg ctgtttgacc ggctcagcgc
    21241 acgtcctgcc ggaatcgacc gtccctcgtg ggacaccgag ggcgccgacg acttccttcc
    21301 cccagctggc accgccagtg ccggggccga gaactcgacc gagccgctcg atcctcaggc
    21361 catcggaccc ctgctggtct gggccatccg aatggtcgaa gacttcgccg acgacatcct
    21421 ggccgggtgg gctgaacact gtcgcctgcg atctctcgcc accacgaacc ggacaacgct
    21481 ctctgggcga gtcgcactgg aggctctggt gctgcccctt ctgcacgaag gagcccagct
    21541 gccggccatg gggaggcagg ggacccgcaa actcgctcgc gcctaccttg ccggcacaac
    21601 cggcgctagc ctcgcccagg tcgaccggct gaatgtacgg cacgggctca cctcgctcgc
    21661 cgcccaacgg cctggcccct gcctcatgca agtaccggtc accggccgga tcaaaggaag
    21721 cccctggcgc gaacgccttg attaccacga agccgccgaa ttgatgcggc atctcggaac
    21781 cgccgccttg gtaatatgcc tatatctgac gggaatgcgt ccgcaggaag ttgcagccct
    21841 gcggtcaggc tgctgtcctg acccgcagcc cgcttcggac ggcacagtcc agcgccacct
    21901 gatccgcagc cgtcacttca agaacgtcac cgatgacgac ggcaaccacg tctccgccgg
    21961 tgaacaacgc gctgtcccct gggttgcggt cacccctgtc gtccgggcga tccgaatcct
    22021 cgaacgcatg gttccccacg gtgagctgtt gttcagcgcc acccatcacg acttcgtggg
    22081 acgacgaggc cgccatggag cgttgaagaa acacgccctg aaccttcgga tcgaggactt
    22141 catcgtgtgg gtgaaccggg aggcccaagt gcaagggctg ccggaccagt ccatccccca
    22201 ggacccccac ggcgcgctcg gcatgtcccg gttcagaagg accctcgcct ggcacatcgc
    22261 ccgacagccc ggagggctgg tcgccctcgc gatccagtac ggacatctgc gcaccatctt
    22321 ggacgcccgg acctcgagcg gttacggctc ccgaagtcgc ggtggcatcc actctgtcct
    22381 cgacatcgag acggccttgg cggccgctga caccgccgcc cacctgcgcg accgtgtggc
    22441 tgctggggag aaggtctccg gcccggccgc tcgccgggcg ttgaccgctg ctgcgatgac
    22501 gccgcggttc gagggccgga tcgtccccac gacgttcgcg aagaaggccg ccaggttcct
    22561 cgctcgggac ggcgttgtgc tttacgacaa cccggacgcc tttctgattt gcgcgttcaa
    22621 gcgggacaac gcgctctgcg aacctgatcc gggagcgacc gcaccgaggc agtacgcctg
    22681 ccagcaaggc tgcggcaacg ccgtccgcac cgacgcccac gcacagcaga tgcgggaaaa
    22741 agccgacgag atcgatctca aggccagcct cctcccggag aagctcgcca accggctgcg
    22801 tcgcaatgcc gacaacttcc gcaagatggc cgacgcccat gacgccaccg cccagaccgc
    22861 cgaggctctg aagtgaacca gcagaaccag gacgaacgca ccttcatccg cgaggcgatg
    22921 gaccggctgc tggctggcaa ggccaccgct tccaacggca gcctcaccgc cgccgcgctc
    22981 gccgccgagg ccggcgtcca ccgcatggct ctctacaagc ggcacacaga cctgaagaac
    23041 gagttcgaag agcgcgtccg cacggagacc aagcaggtcc cggagacgga gaagcagctg
    23101 cgggcgacca tcgccaagct caagaagacg gtcgcgagcc agaaagcgga gatcgacgat
    23161 ctccgccagc aggtgaccct gctcgccatg gccggcgccg tcctcgtcga ccgacaaggc
    23221 accccgtccg cccctgaact gcctcccgcc gatgccccgg acaacgtcat cccgttccgc
    23281 ccgccaacca cctgagctcc ccacaactac gtagcacgtg agcgcagggc tgccaggttg
    23341 gcctacgtcg ccgggggtgg ggcgtcaacc gaaccgaccc ctaggtgcgt gtcaacaagg
    23401 ccaagaacaa gaggaagctc gccgatcagg tagtactcac gtcctcgaac tggctgcttc
    23461 ccatgagctt tgagttcccg tagcaaggtt ttctccagga ggggtgcatc gttcccaggg
    23521 agatctgtga gcaagcgcac tagtcgatcg aacccgtctg atttgtggaa tctcaagcgc
    23581 tgtcgtgggt caccggaagt aatgccaaac tttagatgcc catcggactc attaacgacc
    23641 acgtaaaaca cgttccattc gtatcctgcg cagaacctgc agattccctg cccttgctgc
    23701 acgccggccg gcctaacggt ggttgtgtgt ccattcctgc attgcacgag atgtgggacc
    23761 tggccaccca gccaagattt ttccttgact ctacctccga gtccggctac cgtcttcttg
    23821 aaattctccc aagcagtctt cgggtcttta cctgcacagc tgcggcacat ggtatgacct
    23881 tgctgtatat cgttaggcct cggcgaggct atgtgacctt tagggcacaa gacttggtga
    23941 gattcattaa cccccttcca tgccttgtag atggcgaccc caccgagctc ctctatggcg
    24001 tttcgaaaat acgcctcggc agtttttgtg tccaggccga cgcagattct acatataccc
    24061 ctacctttcc ctgccccgct tggccaaact gctacttcat ggccgccctt acagcgaacc
    24121 ttgtgtggcg ttccagatcc tagccacttt tcctctagga cctctgcccc caaagcggta
    24181 attctgctta cgaaactttc ccatgctctt gctgggtcat ttccagagca ggtgaaacac
    24241 attccctgac cgctctttat ggagcatggc ctagggctgc acgtgtgccc ttttgggcac
    24301 aagcatcggt gaggggtctg cgcccccagc caagcctctt cgagaacttg accacccaag
    24361 gtgtcgacca gttccttgaa ttcgctcaac atctcttttt cgcgtgctgc cctattgcag
    24421 actttgcaga tcccttccat cttcaggagg ttgattggct tgattgatga ctcgtgccct
    24481 tctgcgcagc ggactgaata caatacctta gtgcctgccc acggattcag aacctctccg
    24541 ccatggtcgt cgatcttctc ttcgaagtct tttttcatct gacttgaaga gcccctgcag
    24601 gatgcacacg tgatgcgtcg cgcctgctgc accgaatttg gaactagaaa cagttcatgc
    24661 ccttccttgc atttcgcacg atgttttccc ttggatccca aatattctga ttcgatgact
    24721 tcgatgccgc aggtggcagc cttgattcta aattccagcc aagagcgcgc ccggacttca
    24781 ttcatgttcc ctgtgggcat cagctacccc accctcccct gtggatcact ttctaggcga
    24841 ttatcgccta gaaagtgatc cacgagggcc atttcgtact gagcttcaac tcgtgatgtc
    24901 ggggggcgcc tctatgtctt ggtccgagac cgtcgcgcct tggacctgct cgtgccagac
    24961 ccgccgctcc atcgaccgca cgctcacccg cagcacgtca gtgatctcgc cgttcttctg
    25021 cttgccttca agtcgctcga cggccgccgt cgtagtcgct cccgcatggc tctctcaatg
    25081 tcggtcagcc cgtcaccctg cgcctaccta agggctgtcc cgtaatccct ggtggatcag
    25141 cgcgcggcgt cagatgcggt gcatcgcaag gcggagggtc gccctcatac tggatgtatt
    25201 tgggcgattc gacaacgcag cgagg
//
