LOCUS       NZ_CP031605            22094 bp    DNA     circular CON 21-DEC-2024
DEFINITION  Staphylococcus pseudintermedius strain VB16 chromosome, complete
            genome.
ACCESSION   NZ_CP031605
VERSION     NZ_CP031605.1
KEYWORDS    RefSeq.
SOURCE      Staphylococcus pseudintermedius
  ORGANISM  Staphylococcus pseudintermedius
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus; Staphylococcus intermedius group.
REFERENCE   1  (bases 1 to 2791609)
  AUTHORS   Prapasarakul,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-AUG-2018) Microbiology, Veterinary Science,
            Chulalongkorn University, Henry-Dunant, Bangkok 10330, Thailand
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-FEB-2018
            Assembly Method                   :: Canu v. 1.3
            Assembly Name                     :: VB16
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 40.0x
            Sequencing Technology             :: Oxford Nanopore Technologies
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007833695.1-RS_2024_12_21
            Annotation Date                   :: 12/21/2024 01:51:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,737
            CDSs (total)                      :: 2,655
            Genes (coding)                    :: 2,571
            CDSs (with protein)               :: 2,571
            Genes (RNA)                       :: 82
            rRNAs                             :: 7, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 37 of 84
            Pseudo Genes (incomplete)         :: 50 of 84
            Pseudo Genes (internal stop)      :: 12 of 84
            Pseudo Genes (multiple problems)  :: 13 of 84
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:07:20
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1092384
            Orig. end                         :: 1114478
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031605.1.
            Bacteria and source DNA available from Nuvee prapasarakul,
            Henri-Dunant Rd., Pathumwan, Bangkok 10330, Thailand.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22094
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="5"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22094
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22094
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12094](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12094
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            96..866
                     /gene="sigB"
                     /locus_tag="DRC71_RS04920"
                     /old_locus_tag="DRC71_05005"
     CDS             96..866
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene="sigB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500776.1"
                     /locus_tag="DRC71_RS04920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05005"
                     /product="RNA polymerase sigma factor SigB"
                     /protein_id="WP_015729428.1"
                     /transl_table=11
                     /translation="MTKESKSASAVSPEQINQWIQAYQNDEDHEAQEKLVKHYEKLIES
                     LAYKYSKGQSHHEDLVQVGMVGLIGAINRFDLSFDRKFEAFLVPTVIGEIKRYLRDKTW
                     SVHVPRRIKEIGPRIKKVSDELTNELGRSPSISEIAERLEVSDEDVLEAMEMGQSYNAL
                     SVDHSIEADKDGSTVTLLDIMGQHDDNYELTEKRMILERILPILTDREREIIQCTFIDG
                     LSQKETGERIGLSQMHVSRLQRTAIKKLQEAARK"
     gene            1144..3244
                     /locus_tag="DRC71_RS04925"
                     /old_locus_tag="DRC71_05010"
                     /pseudo=""
     CDS             1144..3244
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003729 - mRNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505949.1"
                     /locus_tag="DRC71_RS04925"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05010"
                     /product="Tex family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTNHFVQAIHNQYQYPVKQIEAVLKLLEEKNTVPFIARYRKEVTG
                     GLDEVEIKQIADEYHYMEQLQKRKDEVIYSIEQQGLLTDELRRDIQQQTKLQRVEDLYR
                     PYKQKKKTRATEAKRKGIEPLAEWIYRQKLDADLGEKAQTFLTDEVTSVEEAIQGAQDI
                     IAEKIADHPQYRKQILKLTQKEGLMTAQKKKKAEDEKAVFEMYYDYQEPLRQVANHRIL
                     AMNRGENEKILQVKIEMDKAILAQNIKKQEVKGHNELSTIVGEAIDDAMKRLIFPSIER
                     EIRTDLTERAEAQAITLFSENLKNLLLQPPLKGKQILGVDPAFRTGCKLAVINPYGTFI
                     EKSVMYPHPPVSKVAEAEKVFLKMVKDFDINLIAIGNGTASRETEQFVARMIQDHALDV
                     QYIIVNEAGASVYSASEIARTEFPDFQVEERSAVSIGRRVQDPLSELVKIDPKSIGVVC
                     S"
     gene            3237..3689
                     /locus_tag="DRC71_RS04930"
                     /old_locus_tag="DRC71_05015"
     CDS             3237..3689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219959.1"
                     /locus_tag="DRC71_RS04930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05015"
                     /product="SprT family protein"
                     /protein_id="WP_015729426.1"
                     /transl_table=11
                     /translation="MNNESLQQLTEQLAMEHFGLPFKHRIYFNRRLRTTGGRYMLSSHD
                     IEINPKQYEHFGEQALVDIIKHELCHYFLHLSGRGHQHKDRDFKVLAEKVGAPRFCQPT
                     ESYTSRANYEYECQRCHSSYVRIRKVNVVKMRCGRCGGHLKLKRYL"
     misc_feature    3994..4010
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.73"
                     /tool="antismash"
     tRNA            4044..4126
                     /anticodon=(pos:1096461..1096463,aa:Leu,seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="DRC71_RS04935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="DRC71_05020"
                     /product="tRNA-Leu"
     gene            4044..4126
                     /locus_tag="DRC71_RS04935"
                     /old_locus_tag="DRC71_05020"
     tRNA            4151..4224
                     /anticodon=(pos:1096567..1096569,aa:Gly,seq:tcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="DRC71_RS04940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="DRC71_05025"
                     /product="tRNA-Gly"
     gene            4151..4224
                     /locus_tag="DRC71_RS04940"
                     /old_locus_tag="DRC71_05025"
     rRNA            4359..5909
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="DRC71_RS04945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="DRC71_05030"
                     /product="16S ribosomal RNA"
     gene            4359..5909
                     /locus_tag="DRC71_RS04945"
                     /old_locus_tag="DRC71_05030"
     misc_feature    complement(4473..4488)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.58"
                     /tool="antismash"
     misc_feature    complement(4688..4701)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 21.07"
                     /tool="antismash"
     misc_feature    complement(5976..5989)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(6180..6194)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.91"
                     /tool="antismash"
     misc_feature    6264..6279
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.8"
                     /tool="antismash"
     misc_feature    6270..6288
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     misc_feature    complement(6334..6348)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.91"
                     /tool="antismash"
     misc_feature    6423..6441
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.56"
                     /tool="antismash"
     rRNA            6449..9308
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="DRC71_RS04950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="DRC71_05035"
                     /product="23S ribosomal RNA"
     gene            6449..9308
                     /locus_tag="DRC71_RS04950"
                     /old_locus_tag="DRC71_05035"
     rRNA            9387..9501
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="DRC71_RS04955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="DRC71_05040"
                     /product="5S ribosomal RNA"
     gene            9387..9501
                     /gene="rrf"
                     /locus_tag="DRC71_RS04955"
                     /old_locus_tag="DRC71_05040"
     gene            9806..9904
                     /locus_tag="DRC71_RS04960"
     CDS             9806..9904
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="DRC71_RS04960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthipeptide"
                     /protein_id="WP_187549439.1"
                     /transl_table=11
                     /translation="MNRVLKLQKLNAEFETKNAKVIFTAGCHIQIN"
     CDS_motif       9806..9865
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNRVLKLQKLNAEFETKNAK"
                     /locus_tag="DRC71_RS04960_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9866..9904
                     /prepeptide="core"
                     /locus_tag="DRC71_RS04960_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-1.80"
                     /molecular_weight="1297.5"
                     /monoisotopic_mass="1296.7"
                     /core_sequence="VIFTAGCHIQIN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNRVLKLQKLNAEFETKNAK"
                     /leader_location="[9805:9865](+)"
     gene            10001..12094
                     /locus_tag="DRC71_RS04965"
                     /old_locus_tag="DRC71_05045"
     CDS             10001..12094
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="DRC71_RS04965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05045"
                     /product="protein kinase domain-containing protein"
                     /protein_id="WP_129945746.1"
                     /sec_met_domain="Pkinase (E-value: 8.3e-16, bitscore: 55.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-06, bitscore:
                     24.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANLIQYYDIFKDITQKNTYTPIFEEKMVMFINEEYQNLPLHGWK
                     IHISSTVENSLEIFYICAKYLTNKNINFKCLKNSDLLKEINDKNCSRSNFGKFITVYPI
                     DSKQAEKILEELSELLEKYDSPYILNDLRYKNCKSLYFRYGRMRFIYGESEDEKKQIRL
                     KNGKVIADPRLPYFYLPEEIEWPFKFKVENDNDNDDDKLLLHEKYEVIKAISMSSKGGI
                     YLAKYKNKEFIIKEYRPNVYVINNFTGEYTYNNEKNVYEKLTEYNFTPKLYDSFKEWEH
                     FYLVLEKVNGETLTNYLAQNMKIYHYENSRRNYIKIVKDILLQIASIIEVLHDIDYVLG
                     DISSENFLIDENNKVYAIDFESCYKIYNTENNYIGTKGFFHPEVKHKVTGKQKDIVGFG
                     FLAMKLFSNSNFLINISYSLCLKNFKLVKKHLKIPEYIYELIELCTSPDYELSIKGIIR
                     CLNSEDIFEIKLYSIINKLEKKMCNINRDKDIINEIILELDIGISNDFNKVLSENNFSL
                     IDGAMAILYDSILKNEKFVKIEKYTEIIFENIKYKNNLINGFQIQQTNRYSPYLYNGTC
                     GFLFLLQIMRKHNEYRNIFSRYENFYYRALQELSKLIIYKTSIAEGLSGVIFIYVNEYR
                     HTKKSEYLDILKGLTEQLFSFCIVEDGEIFFSNQHFEKANSSFRDGDYGILLVLQSVLE
                     LLK"
     gene            12117..13301
                     /locus_tag="DRC71_RS04970"
                     /old_locus_tag="DRC71_05050"
     CDS             12117..13301
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613386.1"
                     /locus_tag="DRC71_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05050"
                     /product="MFS transporter"
                     /protein_id="WP_110160938.1"
                     /transl_table=11
                     /translation="MTRNAYKLIIFGFISTIGSSVFSFACAFHILKNTENSYLYSIYLT
                     LIVITTILSTPISGVFIDSVNNKRLILYSQLSSVAALIIFSLLYDDNVYMIICLGLLLT
                     VPDGINSVIIQKNLQRIVTDNLERVISIRQTVSTLTSFVSPIIGGIVIAFIPLQVIGMM
                     NMLTEAISIILIQSLPIINHQQMKSQFVHSFKEGVQYLVKKKEIMTFLVCAMLNNFLIN
                     VIVVGVPIIAIQQLHLKSTQFGMIESGYTIALFLVSFVMSIYPVKRGVTLFYKIGILIE
                     IVTLFSLGVFLLFPHQNLTSFIFLIATYMLIGVSLPIINTPYGIYLQKAVEEEYKGRVF
                     SLNSSIAQAIIPVSLSFFGFILNNNAAQVFMIDAILMLVVLTGFSITMRKYQFD"
     gene            complement(13371..14639)
                     /gene="ilvA"
                     /locus_tag="DRC71_RS04975"
                     /old_locus_tag="DRC71_05055"
     CDS             complement(13371..14639)
                     /EC_number="4.3.1.19"
                     /GO_function="GO:0004794 - threonine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500771.1"
                     /locus_tag="DRC71_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05055"
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="WP_020219957.1"
                     /sec_met_domain="PALP (E-value: 4.3e-76, bitscore: 253.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVKTTPVQAQDVEDAFLRLNTIVKETPLEKDHYLSLKYDCNVYL
                     KREDLQWVRSFKLRGAYNAIAVLPEEKRNQGITCASAGNHAQGVAFTAKYLNLHAVIFM
                     PVTTPKQKVNQVQFFGGDNVEIKLEGDTFDDCLKSALSFTEQHDMTFIDPFNNVHTIAG
                     QGTLAKEMIEAAKTDNITIDYVFGAIGGGGLMSGVATYFKAHSPSTKLIGVEPLGASSM
                     YQSVQAGEVVTLDNIDKFVDGASVARVGEITFNICRKALDDYVQIDEGAVCSTILDMYS
                     KQAIVAEPAGALSVSALEQYQDQIKGKNVVCIVSGGNNDINRMKEIEERSLLYEEMKHY
                     FILNFPQRPGALRQFVNDVLGPHDDITKFEYLKKSSQNTGTVIIGIQLQNRADLDTLIR
                     NVNQFDPKNIYINENKMLYSLLI"
     gene            complement(14652..15224)
                     /gene="leuD"
                     /locus_tag="DRC71_RS04980"
                     /old_locus_tag="DRC71_05060"
     CDS             complement(14652..15224)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167537.1"
                     /locus_tag="DRC71_RS04980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05060"
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="WP_015729424.1"
                     /transl_table=11
                     /translation="MEIKPITQYSGKTVPLFHDNIDTDQIIPKVHLKRISKTGYGPFLF
                     DEWRYLEDGSDNPDFVLNRPEYEGASILITGDNFGCGSSREHAAWALKDFGFQVIIAES
                     FSDIFYMNCTKNALLPIRLDRASREAIARYPEITIDLPQQIIQTPEQNYHFDIDETWKE
                     KLVNGLDDIAITLKYEALIKDYELKHT"
     gene            complement(15224..16597)
                     /gene="leuC"
                     /locus_tag="DRC71_RS04985"
                     /old_locus_tag="DRC71_05065"
     CDS             complement(15224..16597)
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014613389.1"
                     /locus_tag="DRC71_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05065"
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="WP_110160734.1"
                     /transl_table=11
                     /translation="MGRTLFDKIWDQHTITGQQGEPQLLYIDLHLIHEVTSPQAFEGLR
                     MQKRTLRRPDLTFGTLDHNVPTIDIFNIKDDIANKQIQALQQNCKDFNVTLFDMGSDEQ
                     GIVHMVGPEMGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPK
                     NLKINVTGQLPKGVYAKDIILHLINQHGVDFGTGYALEFAGETIRNLSMEGRMTICNMA
                     IEAGAKYGLIQPDNTTFAYLEGRRYAQNIEDKLDDWRKLYSDDDAQFDKIIELDVTALE
                     PQVTWGTSPEMGVSFSTPFPEIQNVNDERAYQYMGLKPGQLATDIPLGYVFLGSCTNAR
                     ISDLVEASHIVKGNQVHENITAIVVPGSRQVKKEAEAMGLDTIFKDAGFEWREPGCSMC
                     LGMNPDQVPAGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIHGRFVDVRKVVEA"
     gene            complement(16601..17650)
                     /gene="leuB"
                     /locus_tag="DRC71_RS04990"
                     /old_locus_tag="DRC71_05070"
     CDS             complement(16601..17650)
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219955.1"
                     /locus_tag="DRC71_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05070"
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_110160735.1"
                     /transl_table=11
                     /translation="MTFKIVALPGDGIGPEIMSGTLDCLDALASQVDFDYSVDSYAMGG
                     CAIDQYGTPLPDATLDACQSADAILLGAIGGPQWTDPQCRPEQGLLKLRKALNLYANIR
                     PTRVTTDMTYLSPLKQSIVENTDLVIVRELTSGIYFGEPRYLKDDEARDSMTYTKEEII
                     RIAHVGFQLAQSRRQKLTSVDKENVLASSQLWRRTVNEVAEQYPDITVEHLLVDACSMH
                     LIKRPADFDVIITENLFGDILSDEASMLPGSLGLSPSASFSEGGPKLYEPIHGSAPDIA
                     GQNKANPFGMLLSLAMCLRESAERDDMATIIETTVDTLIAKGITTADLGGQYGTTDIFK
                     HFKAFIKGA"
     gene            complement(17647..19179)
                     /locus_tag="DRC71_RS04995"
                     /old_locus_tag="DRC71_05075"
     CDS             complement(17647..19179)
                     /EC_number="2.3.3.13"
                     /GO_function="GO:0003852 - 2-isopropylmalate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167540.1"
                     /locus_tag="DRC71_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05075"
                     /product="2-isopropylmalate synthase"
                     /protein_id="WP_110160736.1"
                     /sec_met_domain="HMGL-like (E-value: 2.4e-92, bitscore:
                     306.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSHIQIFDTTLRDGEQTPGVSFSFEERLKLAEQLEKWGVDVIEA
                     GFPASSQGSFESVQAIARTLKHTTVTGLARCLKSDIDAVYEATKDAVSPSIHVFIATSP
                     IHLESKLHMTEAEVLEAITTHVSYAKERFDIVQFSPEDATRTPLPFLIQSVQTAVDAGA
                     TVINIPDTVGYTYPTEYGNIFKALTEKIKSEVPITYSAHCHDDLGLAVANSMAAIENGA
                     TRIEGTVNGIGERAGNTALEEVALGLYVRQDHYQIQTQIQLELTKQTSDMVSRYAGLRV
                     PRNKAIVGKNAFSHESGIHQDGFLKNPETYEIMTPKLVGVKKTELPLGKLSGKHAFQDK
                     LKQLGYDIDLEEQKVLFKAFKGIADKKKHVTDQDIHALIQNSEHDKHVAYHLETLQLQF
                     VSNGLQSAVVVVRDNDDQHYQDSSIGTGSIVAIYNAVDRIFNVESVLLDYRIDAVSEGR
                     DAQAEVHVQVEVNGQEYVGVGFDHDILYASCKAYVEAISKSVQSIQKEGVAQ"
     gene            complement(19201..20205)
                     /gene="ilvC"
                     /locus_tag="DRC71_RS05000"
                     /old_locus_tag="DRC71_05080"
     CDS             complement(19201..20205)
                     /EC_number="1.1.1.86"
                     /codon_start=1
                     /gene="ilvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500766.1"
                     /locus_tag="DRC71_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05080"
                     /product="ketol-acid reductoisomerase"
                     /protein_id="WP_110160737.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.9e-08, bitscore:
                     31.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKVYYDSSVEKDVLQGKKIAVIGYGSQGHAHAQNLKDNGYDVVI
                     GIRPGRSFDQAEEDGFNVYTVAEAVKQADVVMVLLPDEIQGDVYKNEIEPNLEAGNALA
                     FAHGFNIQFDVIQPPSNVDVFLVAPKGPGHLVRRTFVEGSAVPALFAVQQDASGEARDL
                     ALSYAKGIGSTRAGVLETSFKEETETDLFGEQAVLCGGVTRLIQSGFEVLVEAGYQPEI
                     AYFEVLHEMKLIVDLMYEGGLENMRYSISNTAEFGDYVSGPRVITEETKENMKAVLKDI
                     QDGTFSDRFIKDNEHGFKSFKQMREAQQGHQITAVGQSLREMMPFIKSKSIQK"
     misc_feature    20235..20249
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.71"
                     /tool="antismash"
     gene            complement(20240..20713)
                     /gene="ilvN"
                     /locus_tag="DRC71_RS05005"
                     /old_locus_tag="DRC71_05085"
     CDS             complement(20240..20713)
                     /EC_number="2.2.1.6"
                     /GO_component="GO:0005948 - acetolactate synthase complex
                     [Evidence IEA]"
                     /GO_function="GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166388.1"
                     /locus_tag="DRC71_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DRC71_05085"
                     /product="acetolactate synthase small subunit"
                     /protein_id="WP_110160738.1"
                     /transl_table=11
                     /translation="MRRTFKLRVFDKAGTLNRLTSLFVRRQINIVSITATPTLDEGISE
                     ITFIAEVPDDEKQRTIIQQLIKQVNTLTVEDITNINTFNRELLLIKLKKPMPQQQFDKV
                     LQPYDALVSILKENGQYLYLQATGPQYTLNHLLDDLSSFHIEQVARTGTAGII"
     misc_feature    21329..21344
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.82"
                     /tool="antismash"
ORIGIN
        1 aatcgaatct ttaatggatg aagtaacggt cgataaagat acaggtgtta caattagtat
       61 gattaagtat atcaaaaaag agcaggtgcg aaataatgac gaaagagtcg aaatcagcta
      121 gtgctgtttc acctgaacaa atcaaccaat ggattcaagc gtatcagaat gatgaggatc
      181 atgaagcaca agaaaaactt gtgaaacatt atgaaaaact gatcgaatcc ttagcttata
      241 aatactcaaa aggtcaatca catcacgaag atttagtaca ggttggtatg gtaggactga
      301 ttggtgcgat taatcgattt gatttatcat ttgatagaaa attcgaagct tttttagtcc
      361 ccactgtcat aggtgaaatt aagcgctact taagggataa aacatggagt gtccacgtcc
      421 cacgtagaat taaagaaata gggccgagaa tcaaaaaagt gagcgatgag ctaacaaatg
      481 aattaggacg ttcaccgtca atcagcgaaa ttgcggaacg tcttgaagtt tcggatgaag
      541 atgtgttaga agcaatggaa atggggcaaa gttataacgc tttaagtgtc gaccattcta
      601 ttgaagcgga taaagatggc tctacagtga ctttgttaga tattatgggg caacacgatg
      661 acaattacga gttgactgag aagcgaatga tattagaacg gatacttcct attttaacag
      721 atcgtgaaag agaaattatt caatgtacat ttattgacgg attgagtcaa aaagaaacgg
      781 gagaacgtat cggattaagc cagatgcatg tctcgcgatt acaaagaaca gctattaaga
      841 aattgcagga ggctgcgaga aaatagtgtt gcgataaaag gattgggatt ggattccggt
      901 cctttttgtg tttatggcaa cttgaatttt gtcatctgtg gcttgatttc aaacatagtg
      961 aggaacatct aatcatttta tctgtgaagt agaatagata tggagctttc caggattgat
     1021 aaaagttgca ttagcatggt ttttatgagc tatgatacac atgcgtctta cgtgctcgct
     1081 gacatacttt tagagatacg tgttaaaatg tagaagaaaa gattgagaaa gcggtgaata
     1141 cttttgacaa atcattttgt acaagcaata cataaccaat atcaatatcc agttaaacaa
     1201 attgaagcgg ttctgaaatt attagaagaa aaaaatactg tgccttttat tgcacgttac
     1261 cgtaaagaag tgacgggcgg tttagatgaa gtcgaaatca aacaaattgc tgatgaatat
     1321 cactatatgg aacagttgca aaagcgaaaa gatgaagtga tatatagtat tgagcaacag
     1381 ggtttgctaa cggatgagct tcgacgtgac attcaacagc aaacaaaatt gcaacgtgtg
     1441 gaagatttgt atcgtcccta taagcaaaag aaaaagaccc gtgcaacaga ggcgaaacgt
     1501 aaaggcatcg aacctttagc agaatggatt tatagacaaa agttagacgc tgacttagga
     1561 gagaaagcgc agacgttttt aactgatgaa gtaacctcag tggaagaagc gattcaaggt
     1621 gcgcaggata tcattgctga aaaaattgca gatcatccac aatatcgcaa gcaaatttta
     1681 aagttgacgc aaaaagaagg gctcatgaca gcgcagaaaa agaaaaaggc tgaggatgaa
     1741 aaagccgtgt ttgaaatgta ttatgattat caagaacctc tccgtcaagt tgcgaatcat
     1801 cgtattttag cgatgaatcg tggtgaaaat gaaaaaatat tgcaagtcaa aattgaaatg
     1861 gacaaagcga ttttggcaca aaatattaaa aaacaagaag tcaaaggcca caacgaatta
     1921 tcaacaattg tgggcgaagc gattgatgac gcgatgaaac gtttaatttt tccttccatt
     1981 gaacgtgaaa taagaaccga tttaacagag cgcgcagaag cacaagcgat tacattgttt
     2041 agtgaaaact tgaaaaatct gttgttacaa ccaccattaa aagggaagca aattttaggc
     2101 gtcgatccag cttttcgaac tggctgtaaa ctcgcagtca ttaatccgta tgggacattt
     2161 atcgaaaaat ccgtcatgta cccacatcca cctgtatcta aagtggctga agctgaaaaa
     2221 gtcttcttaa aaatggtgaa agacttcgat attaatttaa ttgcgatagg aaatggaaca
     2281 gcgagtcgtg aaacggaaca gtttgtcgca cgtatgattc aagaccatgc actcgatgtc
     2341 cagtatatta ttgtgaacga ggcaggggca tccgtgtact cggcgtctga gattgcgcgt
     2401 actgaattcc ctgattttca agtggaagag cgtagtgccg tttcgattgg tagacgtgta
     2461 caagatcctt taagtgaact cgttaaaatt gatcctaagt cgatcggtgt cgtttgtagt
     2521 tgaaactgct gttaaccaag tcggtgtgga tgtcaatacg gcttcgagta cattgcttca
     2581 gcacgtgtca gggttatcac gacaaattgc tgataacatt gtgttgtatc gtgaagaaaa
     2641 cggggccatt acccatcatc gtcaactgaa taaggttaaa cgattaggtg cgaaaacgtt
     2701 cgaacaaagt atcggatttt tacgtattgt gaatggtaaa gaaccgttag acaatacagc
     2761 aattcatcca gaaagttatg atgcgactta tcaattatta gaaagtttag aactcaaaat
     2821 tacagatatt ggcacatctg aattagcaaa ggttttatca acattgaata tagcaagtta
     2881 tgcgacgaag ttaaacatcg gtgtccctac gttagaagac atcgtgaagt cattaatcgc
     2941 accaaaccga gatcctcgtg atgattatga aacacctgaa ttaaagtcag atgtattgtc
     3001 gatagaggat ttatcaaaag gtatgaaatt gaatggaaca gtgcgaaatg ttgttgattt
     3061 cggtgctttt gtcgacatcg gcattaagca agacggttta gtacacattt caaaacttgc
     3121 taaaaagttt atcaaacacc cgatggacat tgtcagcgtt ggagacattg tagaagtgtg
     3181 gattgaaaat attgatgaaa ataaagggaa agttgctctg acaatgattg atccaaatga
     3241 ataatgaatc tttgcagcaa ctcactgaac aacttgcaat ggaacatttt ggactccctt
     3301 ttaaacatcg tatttacttt aatcgtcgtt tacgtacaac gggtggacgt tatatgttat
     3361 cttcacatga tattgaaatt aaccctaagc aatacgaaca ttttggtgag caagcacttg
     3421 ttgatattat taaacatgaa ttgtgtcact actttttgca tttgagtggt agagggcatc
     3481 aacataaaga tagagatttt aaagtattag ctgaaaaagt aggtgcgcct agattttgcc
     3541 aaccgactga aagttataca tcaagagcga actatgaata tgaatgccaa aggtgccata
     3601 gtagttatgt tcgcattaga aaagttaatg ttgttaagat gcggtgtggt cgatgtggag
     3661 ggcatttaaa gttgaaaagg tatttataag ttgttgaggc actatatgct gactgaagaa
     3721 tatgagcgat agtgcctttt ttaatgattg attttatttt tgtaatatgt gctttatgag
     3781 aaccaaaagt tagaaaaata gggagatatg tattgacatt atttgtgtgc ctgattataa
     3841 tgacaaagtc gtcaaaaaaa gttgtaagca gttcaaaatg atgtttgaca atgatgacga
     3901 aatgttgtat tctaaaattc gtcgcaaaaa gtgaatgtta aagacagatt acaaacatta
     3961 aaaaaatatt aaaaaagtgt tgacactact aatgtgatat aatataataa tcattgttct
     4021 gaaaaaagaa aacattgttc caagcggtcg tggcggaatg gcagacgcgc taggttgagg
     4081 gcctagtggg agaaatcccg tggaggttca agtcctctcg gccgcatcaa ccatcactta
     4141 aattaagtac gcgggtgtag tttaatggta aaacctcagc cttccaagct gatgttgtga
     4201 gttcgattct catcacccgc tccataaaac aaattgaaat gaacattgaa aactgaatga
     4261 caatatgtca acgttaattc caataatttg agtacttcaa aagtactttc aagagtgatt
     4321 gacttaaaca atcaacgagc tatatcaagc ttacttcttt tatggagagt ttgatcctgg
     4381 ctcaggatga acgctggcgg cgtgcctaat acatgcaagt cgagcgaaca gataaggagc
     4441 ttgctccttt gacgttagcg gcggacgggt gagtaacacg tgggtaacct acctataaga
     4501 ctggaataac tccgggaaac cggggctaat gccggataac atgttgaacc gcatggttct
     4561 acagtgaaag acggtcttac tgtcacttat agatggaccc gcgccgtatt agctagttgg
     4621 tggggtaacg gcctaccaag gcgacgatac gtagccgacc tgagagggtg atcggccaca
     4681 ctggaactga gacacggtcc agactcctac gggaggcagc agtagggaac cctacgcaat
     4741 gggcgaaagc ctgacggagc aacgccgcgt gagtgatgaa ggtcttcgga tcgtaaagct
     4801 ctgttgttag ggaagaacaa atgtgtagta actgtgcaca tcttgacggt acctaaccag
     4861 aaagccacgg ctaactacgt gccagcagcc gcggtaatac gtaggtggca agcgttatcc
     4921 ggaattattg ggcgtaaagc gcgcgtaggc ggttttttaa gtctgatgtg aaagcccacg
     4981 gctcaaccgt ggagggtcat tggaaactgg aaaacttgag tgcagaagag gaaagtggaa
     5041 ttccatgtgt agcggtgaaa tgcgcagaga tatggaggaa caccagtggc gaaggcggct
     5101 ttctggtctg caactgacgc tgatgtgcga aagcgtgggg atcaaacagg attagatacc
     5161 ctggtagtcc acgccgtaaa cgatgagtgc taagtgttag ggggtttccg ccccttagtg
     5221 ctgcagctaa cgcattaagc actccgcctg gggagtacgg tcgcaagact gaaactcaaa
     5281 ggaattgacg gggacccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     5341 gaaccttacc aaatcttgac atcctttgac cgctctagag atagagtttt cctcttcgga
     5401 ggacaaagtg acaggtggtg catggttgtc gtcagctcgt gtcgtgagat gttgggttaa
     5461 gtcccgcaac gagcgcaacc cttgaactta gttgccatca ttcagttggg cactctaagt
     5521 tgactgccgg tgacaaaccg gaggaaggtg gggatgacgt caaatcatca tgccccttat
     5581 gatttgggct acacacgtgc tacaatggac aatacaaagg gcagcgaaac cgcgaggtca
     5641 agcaaatccc ataaagttgt tctcagttcg gattgtagtc tgcaactcga ctacatgaag
     5701 ctggaatcgc tagtaatcgt agatcagcat gctacggtga atacgttccc gggtcttgta
     5761 cacaccgccc gtcacaccac gagagtttgt aacacccgaa gccggtggag taaccatttt
     5821 ggagctagcc gtcgaaggtg ggacaaatga ttggggtgaa gtcgtaacaa ggtagccgta
     5881 tcggaaggtg cggctggatc acctttctaa ggataatata cggaatatca ccatcaggtg
     5941 ataagcggat taacgtgaca tattgtattc agttttgaat gctcattcat ttgaggattc
     6001 agaatgaatt gtacattgaa aactagataa gtaagtatag attttaccaa gcaaaaccga
     6061 gtgacaagcg tttaaaagct tgaaacaaaa aattatcgct agtcgtcaaa tgacgactca
     6121 cataattaat aactggtgat tttggaaaag attgtatttc ggtagacgac atgatgtttt
     6181 gaaaacgttt gtcagtctat gaatcacaag catgagcgaa ggcgcttact gcgcgtaagt
     6241 aactgagtga atgtgaagtg atgaagccga atgcgaacgt ttgccaaaat atcattatgg
     6301 taagcatcgt atttttgatt gcacaaacgt ttatgaaaac gcttgtcagt caacgcattt
     6361 cttgatgagc gcagtgaagt ttacttctcg taaatgaaca agcgaagaaa gaaataaggt
     6421 agaatgcgag cgtttatcat aacgtttaga ttaagttatt aagggcgcac ggtggatgcc
     6481 ttggcactag aagccgatga aggacgttac taacgacgat atgctttggg gagctgtaag
     6541 taagctttga tccagagatt tccgaatggg gaaacccagc acgagttatg tcgtgttatc
     6601 tgcatgtgaa tacatagcat gcaagaaggc agacccggag aactgaaaca tcttagtacc
     6661 cggaggaaga gaaagaaaaa tcgattccct gagtagcggc gagcgaaacg ggaagagccc
     6721 aaaccaataa gcttgcttat tggggttgta ggacactctg tacggagtta caaaagaatt
     6781 tgttagacga ataacctgga aaggttaatc agagaaggta ataatcctgt agtcgaaagc
     6841 gaattctctc ttgagtggat cctgagtacg acggagcacg tgaaattccg tcggaatctg
     6901 ggaggaccat ctcctaaggc taaatactct ctagtgaccg atagtgaacc agtaccgtga
     6961 gggaaaggtg aaaagtaccc cggaagggga gtgaaagaga acttgaaacc ggatcggaac
     7021 aagtagtcag agcccgttaa tgggtgatgg cgtgcctttt gtagaatgaa ccggcgagtt
     7081 acgatctgat gcaaggttaa gcagaaaatg tggagccgta gcgaaagcga gtctgaatag
     7141 ggcgaatgag tatttggtcg tagacccgaa accaggtgat ctacccttgg tcaggttgaa
     7201 gttcaggtaa cactgaatgg aggaccgaac cgacttacgt tgaaaagtga gcggatgaac
     7261 tgagggtagc ggagaaattc caatcgaact tggagatagc tggttctctc gaaatagctt
     7321 tagggctagc ctcaagtgat gattattgga ggtagagcac tgtttggacg aggggcccct
     7381 ctcgggttac cgaattcaga caaactccga atgccaaata atttaacttg ggagtcagaa
     7441 tgtgggtgat aaggtccata ttcgaaagga aacagcccag accaccagct aaggtcccaa
     7501 aatatatgtt aagtggaaaa ggatgtggcg ttgcccagac aactaggatg ttggcttaga
     7561 agcagccatc atttaaagag tgcgtaatag ctcactagtc gagtgacact gcgccgaaaa
     7621 tgtaccgggg ctaaacatat taccgaagct gtggattgtc cttgggacac gggtgggaga
     7681 gggttctata tagtgtagca tgatcgcaag gacatgtgga gcgcttagaa gtgagaatgc
     7741 cggtgtgagt agcgaaagag cggtgagaat cccgtccacc gattgactaa ggtttccaga
     7801 ggaaggctcg tccgctctgg gttagtcggg tcctaagctg aggccgacag gcgtaggcga
     7861 tggataacag gttgatattc ctgtaccacc attattcgtt ttaagcgatg gggggacgca
     7921 gtaggatagg cgaagcgtgc tgttggagtg cacgtccaag cagtgagatt gagtgttagg
     7981 caaatccggc actcttaaga ttgagctgtg atggggagag gaacttgttc ctcgagtcgt
     8041 tgatttcaca ctgccgagaa aagcctctag ctagaataac ggtgcccgta ccgcaaaccg
     8101 acacaggtag tcaagatgag aattctaagg tgagcgagcg aactctcgtt aaggaactcg
     8161 gcaaaatgac cccgtaactt cgggagaagg ggtgctcttt gaggttcacg cttcgaagag
     8221 ccgcagtgaa taggcccaag cgactgttta tcaaaaacac aggtctctgc taaaccgtaa
     8281 ggtgacgtat aggggctgac gcctgcccgg tgctggaagg ttaagaggag tggttagcgc
     8341 aagcgaagct acgaatcgaa gccccagtaa acggcggccg taactataac ggtcctaagg
     8401 tagcgaaatt ccttgtcggg taagttccga cccgcacgaa aggcgtaacg atttgggcac
     8461 tgtctcaacg agagactcgg tgaaatcata gtaccggtga agatgccggt tacccgcgac
     8521 aggacggaaa gaccccgtgg agctttactg tagcctgata ttgaaattcg gtacagtttg
     8581 tacaggatag gtaggagcct tagaagcgtg agcgctagct tacgtggagg cattggtggg
     8641 atactacagg cgggcagttt gactggggcg gtcgcctcct aaagagtaac ggaggcgctc
     8701 aaaggttccc tcagaatggt tggaaatcat tcatagagtg taaaggcata agggagcttg
     8761 actgcgagac ctacaagtcg agcagggtcg aaagacggac ttagtgatcc ggtggttccg
     8821 catggaaggg ccatcgctca acggataaaa gctaccccgg ggataacagg cttatctccc
     8881 ccaagagttc acatcgacgg ggaggtttgg cacctcgatg tcggctcatc gcatcctggg
     8941 gctgtagtcg gtcccaaggg ttgggctgtt cgcccattaa agcggtacgc gagctgggtt
     9001 cagaacgtcg tgagacagtt cggtccctat ccgtcgtggg cgtaggaaat ttgagaggag
     9061 ctgtccttag tacgagagga ccgggatgga catacctctg gtgtaccagt tgtcgtgcca
     9121 acggcatagc tgggtagcta tgtatggacg gagagaggtg aaagcatcta agcatgaagc
     9181 ccccctcgag atgagattcc caacttcggt tataagatcc ctcaaagatg atgaggtgaa
     9241 taggttcgag gtggaagcgt agcgatacgt ggagctgacg aatactaatc gatcgaagac
     9301 ttaatcaaca taattgttca taaggtaatg cttgtgataa atatacttac tatctagttt
     9361 tgaatgtata atattcaaca acttaatctg gtgccaatgg caaagaggtc acacctgttc
     9421 ccatgccgaa cacagaagtt aagctcttta gcgccgatgg tagtcggact tacgttccgc
     9481 gagagtagga cggtgccagg ttatttcaaa agcttcgaag caatcattat tgtttcgggg
     9541 cttttttctt tatatctata aattttcatc aatatatgtt tattttttga caatattact
     9601 ctttaataca tattatacga ataaatatat attttcattc tgttattatg tcattaatta
     9661 tgtaaaaaag agaaaaataa caataagtat tgaaaaagtg aaactagtta gctattataa
     9721 ctatatggta agcatattcg ataatattaa ttaatatttt tattatatta tatggtattt
     9781 taatgttatg aaaggggagc ttaaaatgaa tagagtttta aaactacaaa agctaaatgc
     9841 agaatttgaa actaaaaatg ctaaggttat ttttactgct ggttgtcata tacagataaa
     9901 ttagtgaata gaaataagtg attatcgaat tgcttaccta aaattattta attgttgtac
     9961 atacatttta tagtattata ctatatagga gtgatgaaaa ttggcaaatt taatacaata
    10021 ttatgatatt tttaaagata taacacaaaa aaacacttac actcctattt ttgaagagaa
    10081 aatggttatg tttataaatg aagaatacca aaatttgcca ctacatggat ggaaaattca
    10141 tatatcatca actgtcgaaa actcattaga gatattttac atatgtgcca aatatctgac
    10201 taataaaaat atcaatttta aatgtttaaa aaatagtgat cttttaaagg aaataaatga
    10261 taaaaactgt tctagatcta attttgggaa attcattact gtttatccta tagattcaaa
    10321 gcaggccgaa aagatattag aagaattaag tgaattatta gaaaagtatg attccccata
    10381 tattctcaat gatttaaggt ataaaaactg taaatcacta tactttagat atggtcgtat
    10441 gagatttata tatggagaat cagaagatga aaaaaagcaa attagattga aaaatggaaa
    10501 agtaatagca gaccctaggc ttccttattt ttatctacca gaagaaatag agtggccatt
    10561 taaatttaaa gtagaaaatg ataatgataa tgatgatgat aaactattgc tacatgaaaa
    10621 atatgaagta attaaagcaa tttccatgtc ttcaaaagga gggatttatt tagctaaata
    10681 taaaaacaaa gaatttatta ttaaagaata cagaccaaat gtatatgtaa ttaacaattt
    10741 cacaggggaa tatacataca ataacgaaaa aaatgtatat gaaaaattaa ctgaatataa
    10801 tttcactcct aaattatatg attcttttaa agagtgggag catttttact tagttttaga
    10861 aaaagtaaat ggtgaaacat tgactaacta tttagcacag aacatgaaaa tctatcacta
    10921 tgaaaactct agaagaaatt atattaaaat tgtgaaagat attttattgc aaatagcaag
    10981 tattatagaa gttttgcatg atatagacta tgttttggga gacatatcat ctgaaaattt
    11041 tttaattgat gaaaataata aagtttatgc tatagatttt gaatcttgct ataagattta
    11101 taatacagaa aacaattaca ttggtacaaa aggtttcttt catcctgaag tcaaacataa
    11161 ggtgacaggt aaacaaaaag atatagttgg ctttggattt ttagcgatga aacttttttc
    11221 taattctaat tttttaataa atataagtta tagtttatgt ttgaaaaatt tcaagttagt
    11281 taaaaaacac ttaaagattc ctgaatatat ttatgagttg attgaattat gtacaagtcc
    11341 tgattatgaa ttgtcaataa aaggaataat acgatgttta aatagtgagg atatttttga
    11401 aattaagtta tatagtatca taaataagct ggagaaaaaa atgtgtaata ttaatagaga
    11461 taaagatatt ataaatgaaa taattctaga attagatatt ggtatatcaa atgattttaa
    11521 taaagttttg tcagaaaata atttttcgct aatagatgga gcaatggcaa tactatatga
    11581 ttcgatttta aagaatgaaa aattcgtaaa aatagaaaaa tacactgaaa taatttttga
    11641 aaatataaaa tataaaaaca atttaattaa tggatttcag atacaacaaa caaataggta
    11701 tagtccgtat ttgtataatg gtacttgtgg ttttcttttt cttttacaaa tcatgagaaa
    11761 acataatgaa tatagaaata ttttctctag atacgaaaat ttctattata gagcacttca
    11821 ggaattatca aaacttatta tttataaaac gtccatagct gagggattat caggtgttat
    11881 atttatttat gtaaatgaat atcgacacac taaaaaatca gaatatttag atatattaaa
    11941 ggggttaaca gagcaacttt tttctttttg tattgtagaa gatggagaga tatttttttc
    12001 taatcaacat tttgagaaag caaattcgag ttttagagat ggggattatg gcattttgtt
    12061 agtgctccag tctgttcttg aattattaaa gtaagtattt atgggggtgt tgtgttttga
    12121 cacgtaatgc ttataaatta atcatctttg gttttatttc taccattggt tcaagtgtct
    12181 tcagtttcgc ttgtgccttc catattttga aaaacacaga aaatagttat ttgtacagta
    12241 tttatttaac tttgattgtg atcacaacca ttctttctac gccaatcagt ggtgtgttta
    12301 tagactcagt caacaataaa cggttaattt tgtactctca gttatcaagt gtggctgcac
    12361 tgatcatttt ttctttgtta tacgatgata atgtatatat gattatttgt ttgggtctct
    12421 tattaacggt tcctgatggg ataaactctg tcattattca gaaaaactta caacgtatcg
    12481 tgacagacaa tttagagcgt gtgatatcga ttagacaaac ggtgtcgaca ttgacaagct
    12541 ttgtttctcc aatcattggg ggcattgtca ttgcatttat accgctgcaa gtcatcggga
    12601 tgatgaatat gcttactgaa gcgatttcga ttattcttat acaatcatta ccaattatta
    12661 atcaccaaca aatgaaaagt cagttcgtgc actcttttaa agaaggtgtg caatacttag
    12721 taaagaaaaa agaaattatg acatttctcg tttgtgcgat gttaaacaac tttttaatca
    12781 atgtcatagt tgttggcgta ccgattattg cgatacaaca gttgcatctt aaatcgacac
    12841 agtttgggat gattgaatca ggttacacga ttgcgctatt tttagtgtca tttgtgatgt
    12901 cgatttatcc tgtgaaaaga ggggtcacat tattttataa gattggaatt ttgattgaaa
    12961 ttgtcacttt attttcgctt ggcgtctttt tattgtttcc acatcaaaat ttgacgtcat
    13021 ttatctttct gattgcgaca tatatgttga ttggtgtaag tttaccgatt attaatacac
    13081 cttatggcat ctatttacag aaggcagtag aggaggaata taaagggcgt gtcttttcgc
    13141 tgaattcatc tattgcacaa gcgattatac ctgtttcact gagctttttt ggctttattc
    13201 ttaataataa tgcagcacaa gtttttatga ttgatgcgat attgatgctc gtcgtcttaa
    13261 ctggatttag tatcactatg agaaagtatc aatttgacta atatctcaaa attttaaaaa
    13321 ggagcaaatg tgagaggtgg ttctctcaag tttgctcctt ttgaatcatc ttaaattaat
    13381 aacgaataca gcattttgtt ttcgttaata taaatgtttt taggatcaaa ttgattgacg
    13441 ttacgaatga gcgtgtctag gtctgctcta ttttgaagtt gaatgccgat aatgacagtt
    13501 ccggtatttt gagaagactt cttcagatat tcgaacttgg taatatcatc gtgtggtccg
    13561 agtacatcat tcacgaattg tctgagtgcc cctggacgtt gtgggaagtt caaaataaag
    13621 taatgcttca tttcttcgta taataatgaa cgctcttcaa tttctttcat tcggttaata
    13681 tcgttattcc ctccagaaac gatacagacg acatttttcc ctttaatttg atcttggtat
    13741 tgttctaggg cgctgacgct taatgcgccg gcaggttctg caacgatggc ttgtttcgaa
    13801 tacatgtcta aaatagttga acaaacagcc ccttcgtcaa tttgcacata atcatctaat
    13861 gctttacgac aaatattaaa tgtaatttca cccacacgtg cgacagaagc gccatcgaca
    13921 aatttatcga tattgtccaa tgtcaccact tcgcctgctt gtacggattg atacatactg
    13981 ctcgcgccta atggttccac accaatcagt ttggtagaag gggaatgtgc tttaaaataa
    14041 gtcgctacac ctgacataag cccgccacca ccaatagcgc cgaacacata atcaattgtg
    14101 atattgtccg tttttgccgc ttcgatcatt tcttttgcta atgtcccttg accagcaatt
    14161 gtatgcacat tattaaacgg atcaatgaag gtcatatcgt gttgttcagt aaaactcagc
    14221 gccgacttta agcaatcatc aaatgtatcg ccctctagtt taatttcaac gttatctcca
    14281 ccgaaaaatt gaacttgatt gactttttgt tttggtgttg tcacaggcat gaagataacc
    14341 gcatgtaggt tgaggtattt ggctgtaaac gcgacacctt gcgcatgatt tccggcactt
    14401 gcacatgtga taccttggtt tctcttttct tctggtaata cagcaatggc attgtaagcg
    14461 ccacgtagtt taaatgaacg cacccattga agatcttcgc gctttaaata cacattacaa
    14521 tcatatttga gcgataaata atgatccttt tccaatggtg tttctttaac aattgtgttg
    14581 agacgtaaaa atgcatcttc aacatcttgg gcttgaacag gtgtagtttt tacagacatt
    14641 gttcccactc cttaagtatg ttttagttca tagtctttga ttaatgcttc atattttaat
    14701 gtgatagcaa tatcatctaa gccattcaca agtttttctt tccacgtttc atcaatgtca
    14761 aagtgataat tttgctcggg tgtttggatg atttgttgtg gcaagtcaat tgtgatttca
    14821 ggataacgcg caatcgcttc tcgtgatgca cggtcaagtc gaatcggcaa cagtgcattt
    14881 ttcgtacagt tcatataaaa aatgtcactg aaactttccg caataatcac ttgaaagccg
    14941 aaatctttta acgcccatgc ggcatgctca cgactcgaac cacaaccgaa attgtcaccg
    15001 gtaattaaaa tggatgcccc ttcatattca ggtcgattta agacgaaatc agggttgtct
    15061 gaaccgtctt ctaaataacg ccattcatca aagagaaaag ggccgtaacc tgttttagat
    15121 atccgcttta aatggacttt cggaatgatt tgatcggtat caatattgtc atgaaataat
    15181 gggaccgttt tgcccgaata ttgtgtaatt ggtttaattt ccattacgct tcaaccacct
    15241 ttctcacatc gacaaagcgt ccatgaattg ccgcagctgc ggccatagca ggggatacga
    15301 gatgtgttct tgcaccttta ccttgacggc cttcgaagtt acggttactc gttgacgcac
    15361 agtggacacc agctggcact tggtcggggt tcataccgag acacatgctg catccaggtt
    15421 ctctccattc aaaaccagca tctttaaaaa tcgtatctag gcccatagct tcagcctctt
    15481 tctttacttg acgtgagccg ggtacgacaa tcgctgtaat gttttcgtgt acttgattac
    15541 ctttgacgat gtgactggct tcaactaaat cggaaatacg tgcattcgta catgaaccga
    15601 ggaacacata gcctaacgga atatctgtcg caagttgacc tggttttaag cccatatatt
    15661 gatacgcacg ttcgtcattg acattttgaa tctctgggaa tggtgtacta aagctgacac
    15721 ccatttcagg actcgtgccc caagtgactt gtggttctaa tgctgtcaca tctaattcaa
    15781 tgattttatc gaattgcgcg tcgtcatcac tgtatagctt acgccaatca tcaagtttgt
    15841 cttcaatgtt ttgtgcgtaa cgacgtcctt caaggtatgc aaaagtcgtg ttatctggtt
    15901 gaatcagtcc gtattttgca cctgcttcaa tcgccatatt acaaattgtc atacgaccct
    15961 ccatcgacaa attgcgaatc gtttctccag caaattccag tgcataacct gtaccaaagt
    16021 caacgccgtg ttgattgatt aaatgcaaaa taatgtcttt cgcataaaca cctttaggaa
    16081 gttgcccggt tacgttaatt tttaaatttt tcggtttcgt ttgccatagc gtttgtgtag
    16141 caaatacatg ctcaacttca ctcgtcccga taccgaacgc aatcgcaccg aatgcgccgt
    16201 gtgttgcagt atgggagtcg ccacaaacaa tcgttttacc cggttgcgtt aaccccattt
    16261 caggtccgac catatgtacg ataccttgtt catcagagcc catatcaaac aatgtgacgt
    16321 taaagtcttt acagttttgt tgtaacgctt gaatttgctt gtttgcgata tcatctttaa
    16381 tgttgaaaat atcgatcgtt ggtacattgt gatctaatgt gccaaacgtt aagtcaggtc
    16441 ttcgtaaagt tcgtttttgc attctgagcc cctcaaatgc ttgcggtgac gtcacctcat
    16501 gtatcaaatg caaatcaatg tataacaatt gcggttcacc ttgttgcccg gtaatcgtat
    16561 gttggtccca aattttatcg aaaagtgtac gccccattcg ttatgccccc ttaatgaatg
    16621 ctttaaaatg tttgaaaatg tccgtagtgc cgtattgccc cccaagatca gctgttgtga
    16681 ttcctttagc tattaatgta tcgaccgttg tttcaataat tgttgccata tcatctcgtt
    16741 cagctgattc tcgtaaacac atagcgagtg acaacaacat gccaaacgga tttgctttat
    16801 tttgaccggc gatgtcaggt gctgagccat gaatcggttc gtataatttt ggtccacctt
    16861 cactaaaact tgcggaaggg gagagtccta gtgaaccagg tagcatcgac gcttcatcac
    16921 ttagaatatc gccaaataaa ttttcagtga tgataacatc aaaatcagca ggtcgtttga
    16981 ttaaatgcat actacatgca tcaacaagta aatgttctac cgtaatgtca ggatattgtt
    17041 cagcgacttc attaacagta cgacgccaca attgactgct ggcaagtaca ttttctttat
    17101 caacagatgt gagcttttgg cgacgtgatt gagccaattg aaaaccgaca tgcgcaatgc
    17161 gtataatttc ctctttcgta taagtcattg aatcacgtgc ttcatcgtct ttcaggtagc
    17221 gtggctcgcc aaagtagata ccactcgtca actctctaac gataacaagg tcggtatttt
    17281 cgacaatgga ttgctttaac ggtgataaat acgtcatgtc tgttgtcaca cgtgtgggtc
    17341 gaatattggc atataaattc aatgcttttc gcaatttcag taatccttgt tcaggacgac
    17401 attgtggatc cgtccattga gggccaccaa tcgcaccgag taaaatagca tctgcacttt
    17461 gacaagcatc taatgttgca tcaggtaggg gcgtgccata ttgatcaatg gcacaccccc
    17521 ccatcgcata actgtccacc gaataatcaa aatcaacttg agatgcaagt gcgtccaaac
    17581 aatccaatgt acctgacata atttctggtc caatgccatc gccaggtaaa gctacaattt
    17641 taaaagtcat tgtgcaacac cttctttttg aatggattgc accgatttac ttatcgcttc
    17701 aacataggct ttgcatgagg catataaaat atcgtggtca aaacccacac ctacatattc
    17761 ttgaccattg acttctactt gtacatgaac ttcagcttgt gcatcgcggc cttcagatac
    17821 ggcatcaata cgataatcta acagtacaga ttcgacattg aaaatacgat cgaccgcatt
    17881 ataaatcgca acaatggagc cggtaccaat actagaatct tgataatgtt gatcatcatt
    17941 atcgcgaacg accacaacag cactttgaag gccattcgat acaaattgaa gctgtagtgt
    18001 ttcaagatgg taggcgacat gtttatcatg ctcactattt tgaatcaatg cgtgaatatc
    18061 ttgatcagtg acgtgttttt tcttgtcggc aatcccttta aacgctttaa acaatacttt
    18121 ttgctcttct aaatcaatgt catatccgag ttgtttcaat ttatcttgga acgcatgttt
    18181 acctgataat tttcccagtg gcagttccgt ttttttcaca ccaacgagtt ttggggtcat
    18241 aatttcgtac gtttccgggt ttttcaagaa gccatcttga tgtataccag actcatgact
    18301 aaacgcattt ttcccgacaa tcgctttatt acgtggtact ctcagtccag catagcgtga
    18361 gaccatatca gaagtttgct tcgtcaattc gagttgaatt tgcgtttgaa tttgataatg
    18421 atcttgacgg acgtataaac ctaatgcgac ctcttcaagt gcagtatttc cggcacgttc
    18481 accaatccca ttgaccgttc cttcaatgcg tgttgcacca ttttcgatgg cagccatact
    18541 atttgctaca gctaagccaa ggtcatcatg acaatgggca ctgtacgtaa ttgggacttc
    18601 cgacttgatt ttttctgtga gtgctttgaa aatgttgcca tattcagttg gatacgtata
    18661 gcccaccgta tcaggaatat tgataacagt tgcccctgca tctactgcag tttgtacact
    18721 ttggattaag aatggcaacg gtgtccgtgt cgcatcctct ggtgaaaatt gaacgatatc
    18781 aaaacgttct tttgcataac tcacatgtgt tgttatcgct tcgagcactt cagcttccgt
    18841 catatgaagc tttgactcta agtgaatagg gctcgttgca ataaagacat ggatagaagg
    18901 ggaaacggca tcttttgtcg cttcgtatac ggcatcgata tcagacttta agcaacgtgc
    18961 taaacctgta acagtggtat gttttaacgt tcgagcgatt gcttgtacag attcaaagct
    19021 gccttgactt gaagcaggaa agccagcctc aataacatcg acaccccatt tttcgagttg
    19081 ttcggccagt tttaatcgtt cttcaaagga aaagctgacg cctggtgttt gttcgccatc
    19141 gcgtagtgta gtatcaaaaa tctgaatatg actagacatt ttcattcact ccttaaaaaa
    19201 ttatttttga atgcttttcg atttaataaa tggcatcatt tcacgtaaag attgaccgac
    19261 tgctgtaatt tgatgtcctt gttgtgcttc acgcatttgt ttaaatgatt taaagccatg
    19321 ttcattatct ttaatgaaac gatcgctaaa tgtaccgtct tgaatatctt ttaatacagc
    19381 tttcatattt tctttcgttt cttctgtaat gacacgtgga cctgatacgt agtcaccaaa
    19441 ttctgcagtg ttcgaaatag aataacgcat gttttcaagc ccaccctcat acattaagtc
    19501 aacgatcagt ttcatttcat gtaatacttc gaagtaggcg atttctggct ggtaacctgc
    19561 ttccactaac acttcaaaac cgctttggat gagacgtgtc acgccaccac aaaggacagc
    19621 ttgctcaccg aataaatccg tttccgtttc ttctttaaat gatgtttcta atacgccagc
    19681 acgtgttgac ccgattcctt tggcgtaact taatgccaaa tcacgtgctt cacccgatgc
    19741 atcttgttgc acagcgaata atgctggaac agctgaacct tcaacaaatg ttcgtctaac
    19801 taaatgacct ggacctttcg gcgcaacgag gaaaacatcc acattactcg ggggttggat
    19861 gacgtcaaat tgaatattaa agccgtgcgc aaatgctaat gcgttgcctg cttctaagtt
    19921 aggctcgatt tcatttttat acacgtcacc ttgaatttca tcagggagta acaccatcac
    19981 cacatcggct tgtttgacag cttctgctac ggtgtaaaca ttaaaaccat cttcttctgc
    20041 ttggtcgaat gaacgtccag ggcgaatacc gattacgaca tcatagccat tgtcttttaa
    20101 gttttgtgcg tgggcatgac cttgtgaacc ataaccaata accgcaattt ttttaccttg
    20161 taatacatct ttctctactg atgaatcata ataaactttt gtcatattaa aatgcctcca
    20221 aataatattt tttgattttt caaataattc cagctgtacc agtacgtgca acttgctcaa
    20281 tatgaaatga tgatagatcg tctaaaaggt ggttcaatgt gtattgcggg ccagtagctt
    20341 gtaaatacaa atattgaccg ttttccttca aaatagaaac tagcgcatca tacggttgta
    20401 atactttatc aaattgctgt tgtggcatcg gcttttttag tttaatgagt agtaattcgc
    20461 gattaaacgt attaatgttc gtaatatctt caactgttaa cgtattgact tgcttaatta
    20521 actgttgaat gatcgtacgt tgtttttcgt catcaggtac ttcagcgata aacgtaattt
    20581 ctgaaatccc ttcatctaac gtcggtgtgg cagtaatact cacgatattg atttggcgtc
    20641 ttacgaataa acttgttaat cggttaagtg tgccggcttt atcgaaaacg cgtaatttga
    20701 atgttcgtct cataacagtc cctccatctc atggttcgct ttgccacttg gtaccatagg
    20761 caatacaggt tctacaggtg aaatgcgaat ttcaattaat gcaggaccat tgtgtaaaaa
    20821 tgctgcatcg atttgcgctt ctaaacattt cgggtcatcg attaaaaagc ctttcacacc
    20881 ataggcttca ctcattttca taaaatcggg ttgatcgtta aatactgaat gtgaaaaacg
    20941 ttggttaaag aatttgtctt gccattgttt caccattccg agcgtaccgt tgttaatcaa
    21001 tacgatttta atatttaagt taaattcgtt cagtaaagcc atttcttggt tcgtcatttg
    21061 aaaaccacca tcaccgacga atgctacgac agtttcattt ggttttgcaa attttgcacc
    21121 gatagcggct gggataccga atcccatcgt tccgagtccg ccacttgtaa tcagttgacc
    21181 gtacgtttgg aacgggtaga actgagcgac ccacatttgg tgttggccga catctgttgc
    21241 tacataagct ttaccttgtg taatttcacc aatgtattca attgcacgtt gaggtttaca
    21301 aaacttttca agcggatcat caacatattt gaatggatgt tcgtcttgat agcctttcac
    21361 cgttgtcagc catgcgtcgt gattgatttt tttcgtatca tattttaata acgcttcaat
    21421 tacatttttt acatctgcta caatcccgag gtcagtttta atgattttgt cgatttctga
    21481 cggatcaata tcgacatgta caatggttgc atttggcgca aattcatctg gattacttgc
    21541 taaacggtca tcaaatcgcg agccaaagtt aatgagtaag tcacattccg tcaatgccat
    21601 attacttgca taggaaccgt gcatgccgcc catacctaag aagtgggggt catcataagg
    21661 aatcgcacct aaaccgtgaa gcgtcgtcac gacaggaatt tgatatttgt cgactaactg
    21721 ccgtaattgc gcattcgatt tagagaaatg aattcctgca ccagctaaaa tgacagggcg
    21781 ctctgacgtt tttaaataat cattcagttt ttgaatttca tcaatgtcag gctttgtatt
    21841 gacgtaatag ccaggtgtat tgactgtatt atcgacggtt gaatctgttg ataaaatgcc
    21901 catatctttc ggaaaatcaa tcactaccgg tcctttacga ccagaatttg cgacatgaaa
    21961 agcttcttta ataatgcgcg gaatttcttt cacatcgttg acttgataat tatgtttcgt
    22021 aatcggcgtt gtcattgata aaatgtctgc ttcttggaaa gcgtctttac caatgcctgg
    22081 tgtcgccact tgac
//
