LOCUS       NZ_VLJL01000002        17881 bp    DNA     linear   CON 03-JUL-2024
DEFINITION  Bacillus subtilis J27 BacJ27_scaffold_9, whole genome shotgun
            sequence.
ACCESSION   NZ_VLJL01000002
VERSION     NZ_VLJL01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis J27
  ORGANISM  Bacillus subtilis J27
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 131138)
  AUTHORS   Gladden,J.
  TITLE     Genome sequencing of lignin-degrading bacterial isolates
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 131138)
  AUTHORS   Gladden,J., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-JUL-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.0.19
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 510.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007829735.1-RS_2024_07_03
            Annotation Date                   :: 07/03/2024 03:39:38
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,202
            CDSs (total)                      :: 4,129
            Genes (coding)                    :: 3,934
            CDSs (with protein)               :: 3,934
            Genes (RNA)                       :: 73
            rRNAs                             :: 5, 5, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 5 (5S)
            partial rRNAs                     :: 5, 1 (16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 195
            CDSs (without protein)            :: 195
            Pseudo Genes (ambiguous residues) :: 0 of 195
            Pseudo Genes (frameshifted)       :: 128 of 195
            Pseudo Genes (incomplete)         :: 68 of 195
            Pseudo Genes (internal stop)      :: 26 of 195
            Pseudo Genes (multiple problems)  :: 24 of 195
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:40:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 113257
            Orig. end                         :: 131138
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VLJL01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..17881
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..17881
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..17881
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10891](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10891
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            521..727
                     /gene="spoIIIAC"
                     /locus_tag="L604_RS03485"
                     /old_locus_tag="L604_001000001350"
     CDS             521..727
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390321.1"
                     /locus_tag="L604_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001350"
                     /product="stage III sporulation protein AC"
                     /protein_id="WP_003153142.1"
                     /transl_table=11
                     /translation="MGVDVNVIFQIAGVGIVVAFLHTILDQMGKKEYAQWVTLLGFIYI
                     LFMVATIVDDLFKKIKAVFLFQG"
     gene            734..1135
                     /gene="spoIIIAD"
                     /locus_tag="L604_RS03490"
                     /old_locus_tag="L604_001000001360"
     CDS             734..1135
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390320.1"
                     /locus_tag="L604_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001360"
                     /product="stage III sporulation protein AD"
                     /protein_id="WP_003230228.1"
                     /transl_table=11
                     /translation="MQIDIVQIVGLGLIATFLSLIVKEQKPTFAFLIVVFAGCAIFLYL
                     VDQIYDIIRMIEKIAINANVNMVYVETILKIIGIAYIAEFGAQLTKDAGQGAIASKIEL
                     AGKILILVMAVPILTVIIETILGLIPSMS"
     misc_feature    complement(1153..1167)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.21"
                     /tool="antismash"
     gene            1154..2353
                     /gene="spoIIIAE"
                     /locus_tag="L604_RS03495"
                     /old_locus_tag="L604_001000001370"
     CDS             1154..2353
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390319.2"
                     /locus_tag="L604_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001370"
                     /product="stage III sporulation protein AE"
                     /protein_id="WP_003230230.1"
                     /transl_table=11
                     /translation="MKRFQWVLLLAVLIIAGRAEIVQAAGNAEQTEDHAETAEQLAERT
                     AASLETDKIGEFWNDIMTEYGGLLPESQKGSLMEFINGDKSFSPQEWLKALFSYLFHEV
                     LANGKLLGTLILLTIFCVILQLLQNAFQQSTVSKVAYSIVYMVLIILALNSFHVAINYA
                     TEAIQTMTSFILALIPLLLALLASSGGAVSAAFFHPVILFLMNTSGLLIQNIVMPLIFL
                     SAILSIVSTMTEQYKVTQLANLLRNIAIGALAVFLTIFLGVISVQGASAAVTDGITLRT
                     AKFITGNFIPVLGRMFTDATDTVISASLLLKNTVGILGVAILICIAAFPAIKVLSLAFI
                     YKLAAAILQPLGGGPVITCLDVISKSVIYIFAALAIVSLMFFLSLTVIITAGNLTMMMK
                     "
     gene            2367..2987
                     /gene="spoIIIAF"
                     /locus_tag="L604_RS03500"
                     /old_locus_tag="L604_001000001380"
     CDS             2367..2987
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390318.1"
                     /locus_tag="L604_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001380"
                     /product="stage III sporulation protein AF"
                     /protein_id="WP_015251730.1"
                     /transl_table=11
                     /translation="MSFLTEWLTTIVLFILFAIVIDMLLPSSSMQKYAKMVVSLLLIVV
                     MLTPIFKLFKTDPEIIFEYLTKNGQSESADIKNQINSKKIEIQASQRAYILEEMAVQLK
                     KKAEERFSHDEYKVGRIKLTAGEKVDSEEDIKTISVYMAPSSEKTVQTVAPVHIDTDHA
                     YVTKEAAEQKEAKQIKTQLADIWEIGSEKITVHMEGGESVGNE"
     gene            2980..3669
                     /gene="spoIIIAG"
                     /locus_tag="L604_RS03505"
                     /old_locus_tag="L604_001000001390"
     CDS             2980..3669
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIIIAG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390317.2"
                     /locus_tag="L604_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001390"
                     /product="stage III sporulation protein AG"
                     /protein_id="WP_033885014.1"
                     /transl_table=11
                     /translation="MNKNGLWNVLKKQFLPGQMKDGEKPKLTKYHYFLFVFVLGVSFML
                     VSQLFSSPEKTENAKTITAVSSQHSAGSKEKTAEVFKASKSDKPKDSIDDYEKEYENQL
                     KEILETIIGVDDVSVVVNVDATSLKVYEKNKSNKNTTTEETDKEGGTRSVTDQTSEEEI
                     VMIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQIKQTIIEAVTRVLDVPSHRVAVAP
                     KKIKEDS"
     gene            3670..4326
                     /gene="spoIIIAH"
                     /locus_tag="L604_RS03510"
                     /old_locus_tag="L604_001000001400"
     CDS             3670..4326
                     /codon_start=1
                     /gene="spoIIIAH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390316.2"
                     /locus_tag="L604_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001400"
                     /product="stage III sporulation ratchet engulfment protein
                     SpoIIIAH"
                     /protein_id="WP_003230250.1"
                     /transl_table=11
                     /translation="MLKKQTVWLLTMLSLVVVLSVYYIMSPESKNAVQMQSEKSASDSG
                     EVATEKAPAKQDTKEKSGTETEKGKEDGTKGTKDSSADKETSAEASEKGTVVTETADDD
                     LFTTYRLDLEDARSKEREELNAIVSSDDATAKEKSEAYDKMTALSEVEGTEKQLETLIK
                     TQGYEDALVNAEGDKINITVKSDKHSKSKATAIIDLVAKEIKTMKDVAVTFEPSK"
     gene            4483..4962
                     /gene="accB"
                     /locus_tag="L604_RS03515"
                     /old_locus_tag="L604_001000001410"
     CDS             4483..4962
                     /EC_number="6.4.1.2"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0003989 - acetyl-CoA carboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="accB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390315.1"
                     /locus_tag="L604_RS03515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001410"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="WP_144530376.1"
                     /transl_table=11
                     /translation="MLNIKEIHELIKAIDESTIDEFVYENEGVSLKLKKHEAGTVQVMQ
                     QAPAAPVQAQAPQAVQPQAQQAAAPAQEVPKQDENLHKITSPMVGTFYASSSPEAGPYV
                     TAGSKVNENTVVCIVEAMKLFNEIEAEVKGEIVEVLVENGQLVEYGQPLFLVKAE"
     gene            4974..6326
                     /gene="accC"
                     /locus_tag="L604_RS03520"
                     /old_locus_tag="L604_001000001420"
     CDS             4974..6326
                     /EC_number="6.3.4.14"
                     /GO_component="GO:0009317 - acetyl-CoA carboxylase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004075 - biotin carboxylase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="accC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390314.2"
                     /locus_tag="L604_RS03520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001420"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_003230253.1"
                     /sec_met_domain="RimK (E-value: 4.1e-08, bitscore: 26.3,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.3e-09, bitscore:
                     31.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.6e-11,
                     bitscore: 36.6, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.1e-07, bitscore:
                     24.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKLLIANRGEIAVRIIRACRELGIETVAVYSEADKDALHVQMA
                     DEAFCIGPKASKDSYLNVTNIVSVAKLTGTDAIHPGYGFLAENADFAELCEEVNVTFVG
                     PSADAISKMGTKDVARETMKQAGVPIVPGSQGIIENVEEAVSLANEIGYPVIIKATAGG
                     GGKGIRVARTEEELINGIKITQQEAATAFGNPGVYIEKYIEDFRHVEIQVLADNYGNTI
                     HLGERDCSIQRRLQKLLEESPSPALDSEIREQMGDAAVKAAKAVGYTGAGTVEFIYDYN
                     EQRYYFMEMNTRIQVEHPVTEMVTGTDLIKEQIKVASGMELSLKQEDVEFEGWAIECRI
                     NAENPSKNFMPSPGEIKMYLPPGGLGVRVDSAAYPGYSIPPYYDSMIAKVITYGKTRDE
                     AIARMKRALSEFVIEGIETTIPFHLKLLEHETFVSGEFNTKFLETYDVMGS"
     gene            6347..6754
                     /gene="yqhY"
                     /locus_tag="L604_RS03525"
                     /old_locus_tag="L604_001000001430"
     CDS             6347..6754
                     /codon_start=1
                     /gene="yqhY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390313.2"
                     /locus_tag="L604_RS03525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001430"
                     /product="fatty acid biosynthesis protein YqhY"
                     /protein_id="WP_003230254.1"
                     /transl_table=11
                     /translation="MKDNSLLKMDHEDTHLGKVEIAPEVIEVIAGIAASEVDGVAEMRG
                     NFATGVVERFGKVNHGKGVKVDLADDGITIDVYCVVTFGVSIPKVAASVQENIRQTLLN
                     MTSLSINEINIHIVGIQFDTKAQEVQIDEEM"
     misc_feature    complement(6774..6788)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            7018..7413
                     /gene="nusB"
                     /locus_tag="L604_RS03530"
                     /old_locus_tag="L604_001000001440"
     CDS             7018..7413
                     /GO_process="GO:0006353 - DNA-templated transcription
                     termination [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390312.2"
                     /locus_tag="L604_RS03530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001440"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_144530377.1"
                     /transl_table=11
                     /translation="MKRRTAREKALQALFQIDVSDIAVNEAIEHALDEEKTDPFFEQLV
                     HGVLEHQDQLDEMISKHLVNWKLDRIANVDRAILRLAAYEMAYAEDIPVNVSMNEAIEL
                     AKRFGDDKATKFVNGVLSNIKSDIEHS"
     gene            7425..8276
                     /gene="folD"
                     /locus_tag="L604_RS03535"
                     /old_locus_tag="L604_001000001450"
     CDS             7425..8276
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="folD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390311.1"
                     /locus_tag="L604_RS03535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001450"
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD"
                     /protein_id="WP_003230259.1"
                     /transl_table=11
                     /translation="MTATIIDGKETAREKREQLAKEVEELKKQGVTPGLAVILIGDDPA
                     SHSYVRGKKKAAETMGMNFKLDQFDSSLTEAELLSIIDQYNQDPEFHGILVQLPLPDHI
                     SEKAVIERISPDKDVDGFHPLNVGKMLLGEDTFLPCTPHGIVELLKKTNIDLSGKEVVV
                     VGRSNIVGKPVGQLLLNENATVTYCHSRTENITEHTKKADILVVAVGRANFISADQIKE
                     GAVVIDVGVNRLENGKLCGDVEFEGAKEKASFITPVPGGVGPMTITMLAHNTVKSAKRT
                     LS"
     gene            8414..9760
                     /gene="xseA"
                     /locus_tag="L604_RS03540"
                     /old_locus_tag="L604_001000001460"
     CDS             8414..9760
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390310.2"
                     /locus_tag="L604_RS03540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001460"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_144530378.1"
                     /transl_table=11
                     /translation="MGEAAYVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRGH
                     IYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQPD
                     GVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLKRRY
                     PLVKVIVLPALVQGENASRSIVTRIEEANEKEICDVLIVGRGGGSIEELWAFNEEIVAR
                     AIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTAEVRMT
                     RAMKQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLDRKSRQL
                     ERETYRLEALHPHEQLKQARTRYQEQTNQLRKNMNIQMKQLHSQFQTVLGKLNALSPLQ
                     VMERGYSLAYKEDKLIKSVSQIEEQDRLEVKLKDGVLTCEVLEKRGEEK"
     gene            9757..10011
                     /gene="xseB"
                     /locus_tag="L604_RS03545"
                     /old_locus_tag="L604_001000001470"
     CDS             9757..10011
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /gene="xseB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390309.2"
                     /locus_tag="L604_RS03545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001470"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_003226409.1"
                     /transl_table=11
                     /translation="MTDVKKNENMTFEEAMKGLESIVSKLEEGDVPLEQAINYFQEGMA
                     LSKMCHEKLQKVEKQMDFILKEDGELAPFSVQEEDEGDK"
     gene            10001..10891
                     /gene="ispA"
                     /locus_tag="L604_RS03550"
                     /old_locus_tag="L604_001000001480"
     CDS             10001..10891
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390308.2"
                     /locus_tag="L604_RS03550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001480"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_003230262.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-64, bitscore:
                     211.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKLTSFLADRKKTIENQLSVYTEKLDMPDSLKKSMLYSLQAGG
                     KRLRPLIVLAVLNAYGKSEKDGIPVGCAVEMIHTYSLIHDDLPCMDDDDLRRGKPTNHK
                     VFGEATAVLAGDGLLTESFKLITSHVSDEVSAEKRLRLVNELISAAGTEGMVGGQVADM
                     EAENRQVTLEELESIHERKTAKLLGFCVIAGAILADAPEEDIETLRTFSSHIGIGFQIR
                     DDILDLEGSEEKIGKRVGSDTTNDKSTYPSLLSLEGAKHKLDVHIKEAKRLIGGLSLQK
                     DLLYELCDLIAARDH"
     gene            11066..12967
                     /gene="dxs"
                     /locus_tag="L604_RS03555"
     CDS             11066..12967
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390307.1"
                     /locus_tag="L604_RS03555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_144530379.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.1e-118,
                     bitscore: 387.7, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLSIQDPSFLKNMSIDELEKLSDEIRQFLITSLSASGGHIGPN
                     LGVVELTIALHKEFNSPKDKFLWDVGHQSYVHKLLTGRGKEFATLRQYKGLCGFPKRSE
                     SEHDVWETGHSSTSLSGAMGMAAARDIKGTDEYIIPIIGDGALTGGMALEALNHIGDEK
                     KDMIVILNDNEMSIAPNVGAIHSMLGRLRTAGKYQWVKDELEYLFKKIPAVGGKLAATA
                     ERVKDSLKYMLVSGMFFEELGFTYLGPVDGHSYHELIENLQYAKKTKGPVLLHVITKKG
                     KGYKPAETDTIGTWHGTGPYKINTGDFVKPKAAAPSWSGLVSGTVQRMAREDGRIVAIT
                     PAMPVGSKLEGFAKEFPDRMFDVGIAEQHAATMAAAMAMQGMKPFLAIYSTFLQRAYDQ
                     VVHDICRQNANVFIGIDRAGLVGADGETHQGVFDIAFMRHIPNMVLMMPKDENEGQHMV
                     HTALSYDEGPIAMRFPRGNGLGVKMDEQLKTIPIGTWEVLRPGNDAVILTFGTTIEMAI
                     EAAEELQKEGLSVRVVNARFIKPIDEKMMKSILKEGLPILTIEEAVLEGGFGSSILEFA
                     HDQGEYHTPIDRMGIPDRFIEHGSVTALLKEIGLTKQQVANRIRLLMPPKTHKGIGS"
     gene            12964..13809
                     /gene="yqxC"
                     /locus_tag="L604_RS03560"
                     /old_locus_tag="L604_001000001500"
     CDS             12964..13809
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene="yqxC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390306.2"
                     /locus_tag="L604_RS03560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001500"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_031600677.1"
                     /transl_table=11
                     /translation="MTSKKERLDVLLVERGLAETREKAKRAIMAGIVYSNENRLDKPGE
                     KIDRDLPLTVKGNPLRYVSRGGLKLEKALKEFPVSVKDKIMIDIGSSTGGFTDCALQNG
                     AKQSYAVDVGYNQLAWKLRQDERVVVMERTNFRYATPADFTKGMPEFATIDVSFISLRL
                     ILPVLRTLLVPGSDCMALVKPQFEAGRESVGKKGIVRDPKVHADVLKRMISFSAAEGYI
                     CKGLSFSPITGGDGNIEFLLHLHWPGEGQDGQELPEEEIMRVVEEAHKTLKEKKADVPE
                     "
     gene            13907..14356
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /locus_tag="L604_RS03565"
                     /old_locus_tag="L604_001000001510"
     CDS             13907..14356
                     /codon_start=1
                     /gene="argR"
                     /gene_synonym="ahrC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390305.1"
                     /locus_tag="L604_RS03565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001510"
                     /product="arginine repressor ArgR"
                     /protein_id="WP_003230265.1"
                     /transl_table=11
                     /translation="MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDI
                     KELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQ
                     AIGALMDNLDWDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL"
     gene            14393..16123
                     /gene="recN"
                     /locus_tag="L604_RS03570"
                     /old_locus_tag="L604_001000001520"
     CDS             14393..16123
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390304.2"
                     /locus_tag="L604_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001520"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_144530380.1"
                     /transl_table=11
                     /translation="MLAELSIKNFAIIEELTVSFERGLTVLTGETGAGKSIIIDAISLL
                     VGGRGSSEFVRYGEAKAELEGLFLLESGHPVLGVCAEQGIDVSDEMIVMRRDISTSGKS
                     VCRVNGKLVTIASLREIGRLLLDIHGQHDNQLLMEDENHLQLLDKFAGAEVESALKTYQ
                     EGYQRYMKLLKKLKQLSESEQEMAHRLDLIQFQLEEIESAKLELNEDEQLQEERKQISN
                     FEKIYESLQNAYNALRSEQGGLDWVGMASAQLEDISDINEPLKKMSESVSNSYYLLEDA
                     TFQMRNMLDELEFDPERLNYIETRLNEIKQLKRKYGATVEDILEYASKIEEEIDQIENR
                     DSHLQSLKKELDSVGKDVAVEAANVSQIRKTWAKKLADEIHRELKSLYMEKSTFDTEFK
                     VRTASRNEEAPLVNGQPVQLTEQGIDLVKFLISTNTGEPLKSLSKVASGGELSRVMLAI
                     KSIFSSQQDVTSIIFDEVDTGVSGRVAQAIAEKIHKVSIGSQVLCITHLPQVAAMADTH
                     LYIAKELKDGRTTTRVKPLSKQEKVAEIGRMIAGVEVTDLTKRHAKELLKQADQVKTTG
                     "
     gene            16298..17578
                     /gene="spoIVB"
                     /locus_tag="L604_RS03575"
                     /old_locus_tag="L604_001000001530"
     CDS             16298..17578
                     /EC_number="3.4.21.116"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoIVB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_390303.2"
                     /locus_tag="L604_RS03575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001530"
                     /product="SpoIVB peptidase"
                     /protein_id="WP_144530381.1"
                     /transl_table=11
                     /translation="MPDNIRKAVGLILLVSLLSVGLCKPLKEYLLIPTQMRVFETQTQA
                     IETSLSVNAQTSESSEAFTVKKDPHEIKVTGKKSGESELVYDLAGFPIKKTKVHVLPDL
                     KVIPGGQSIGVKLHSVGVLVVGFHQINTSEGKKSPGETAGIEAGDIIIEMNGQKIEKMN
                     DVAPFIQKAGKTGESLDLLIKRDKQKIKTKLIPEKDEGEGKYRIGLYIRDSAAGIGTMT
                     FYEPKTKKYGALGHVISDMDTKKPIVVENGEIVKSTVTSIEKGTGGNPGEKLARFSSER
                     KTIGDINRNGPFGIFGTLHQPIQNNISDQALPVAFSTEVKKGPAEILTVIDDDKVEKFD
                     IEIVSTTPQKFPATKGMVLKITDPRLLKETGGIVQGMSGSPIIQNGKVIGAVTHVFVND
                     PTSGYGVHIEWMLSEAGIDIYGKEKAS"
     gene            17686..>17881
                     /locus_tag="L604_RS21140"
                     /old_locus_tag="L604_001000001540"
     CDS             17686..>17881
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025677.4"
                     /locus_tag="L604_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L604_001000001540"
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /protein_id="WP_186437508.1"
                     /transl_table=11
                     /translation="MSQAGSGVIKRILKDHFDGFWRMHSDLFPKSYREDIKETVEKAIR
                     CGTKDLGYARYECLGCDGEP"
ORIGIN
        1 gctgtattca ttgtggtagc gacaacatgg acaggttttg agatggcgaa gatttataca
       61 gaacggccgc ggcaaatccg ccagctgcgt gcggcgcttc aatccctcga ggctgaaatc
      121 atgtacggcc atacaccgct tcatactgct tcacagcaga ttgccaaaca gctcgcacag
      181 cctgtttcag ctcttttttc cgcattcagt aatcagctgg acaagggaag tgattccgcg
      241 aaaacggcgt gggagcaaag cttaaagaag gtatgggaca ccctgtcttt gaaaaaaagc
      301 gaatacgaag tgctgaagca gtttggcgag acgctcggga ttcatgatcg aatctctcag
      361 caaaagcaca tcaagctggc gctgacacat ttggaagcct ctgaagcgga tgctgagcag
      421 gcgcaagcga aaaacgaaaa gatgataaaa agtttgggct ttttagcggg tttgttactc
      481 attcttctat tgatgtaaac gtgaggggag caaaaataaa atgggagtag acgtgaatgt
      541 catatttcaa atcgccggag tgggaatcgt ggtcgcattt ttacacacga tattggatca
      601 gatgggcaag aaagaatacg ctcagtgggt gacgctgtta ggttttatct atattttatt
      661 tatggtcgcc acgattgtag atgacctatt taaaaagata aaagctgtgt ttttattcca
      721 aggatagggg ggcttgcaga ttgacattgt tcaaattgta ggtttagggc tgatcgccac
      781 cttcctttct ttaattgtaa aagaacaaaa gccgactttt gcgtttttaa tcgtcgtttt
      841 tgccggatgt gccatttttc tttatttagt agaccaaatc tacgacatta ttcgaatgat
      901 agaaaaaatt gcgattaatg caaatgtcaa catggtctat gttgaaacca ttttaaagat
      961 tatcggaatc gcctatattg ctgaattcgg ggcacagctc acaaaagatg ccggtcaagg
     1021 agccatcgcc tcgaaaatag aattggcggg gaaaatttta attctcgtta tggctgtgcc
     1081 tattttaacc gtcattatcg aaacgattct cggacttata ccttctatgt cataaccgaa
     1141 aggaggcggt agattgaagc gctttcaatg ggttttgctt ttggccgtgc tgatcatagc
     1201 aggccgtgca gaaattgtac aagcagctgg taatgcagaa caaacggaag accatgctga
     1261 aacagctgag caattagcgg aaaggacagc agcctcgctt gaaacagata agatcgggga
     1321 attttggaat gacattatga cagaatacgg cggactgctg ccggaaagcc aaaaaggcag
     1381 cttaatggag tttatcaatg gcgataaatc attctcaccg caagaatggc tgaaagctct
     1441 cttttcttat ttgtttcatg aagtgcttgc caacggaaag ctgctgggca cattgatttt
     1501 gctcacgatt ttttgcgtca ttctgcagct tttgcaaaat gcttttcagc aaagcaccgt
     1561 cagtaaggtc gcttactcaa ttgtgtacat ggtgctgatt atccttgcgc ttaatagctt
     1621 tcatgtggca attaactatg caactgaggc gattcagacg atgaccagct ttatcctggc
     1681 gctcattccg ctcctcttgg cgcttttggc ttcctcaggc ggagctgtat ctgctgcctt
     1741 ctttcatcct gttatcctct ttctgatgaa cacaagcggt ctcttgattc agaatatcgt
     1801 catgccgctg attttcttat cagcgattct gagcattgtc agcacgatga ctgaacaata
     1861 caaagtaact cagctggcca acctgctcag aaatatcgcc atcggagcac tggctgtttt
     1921 tcttaccatc tttctcggcg tcatctctgt tcagggagcc tccgctgcag tgacagacgg
     1981 cattacgctc aggacggcta aatttataac cggaaatttt attcctgtgc ttggccgaat
     2041 gtttacagac gcaacagata cagtaatcag cgcctcttta ctgctgaaaa atacggtagg
     2101 gattctcggt gtcgctattt tgatctgtat cgcggcattt ccggcaatca aagtgctttc
     2161 cctcgctttt atttataagc tggcagccgc gattcttcag ccgcttggag gcgggcccgt
     2221 catcacctgc ctcgacgtca tcagcaaaag cgtcatttat atttttgcag ctctcgctat
     2281 tgtgtctctc atgttttttt taagccttac tgtcataatc acagccggaa acctcacgat
     2341 gatgatgaaa tgaaggaggc aggcgaatga gttttttaac ggaatggctt accactatcg
     2401 tgttgtttat cctatttgca attgtgattg atatgctgct gccgagctcc agcatgcaaa
     2461 agtacgcaaa aatggtagtc agcctgctct tgattgtcgt catgcttacg ccgattttta
     2521 aacttttcaa gacagacccc gaaatcatct ttgaatacct cacaaaaaac gggcagtcag
     2581 agtctgccga cataaaaaat caaatcaatt caaaaaaaat agaaatacaa gcttcccagc
     2641 gcgcatatat tctagaagaa atggctgtcc aactaaaaaa gaaagcggag gagagattca
     2701 gtcatgatga atataaagta ggccgcatca aactcacggc aggagaaaag gtagattcag
     2761 aagaggatat taaaacaatc agcgtgtata tggccccgtc ttctgaaaaa acggtccaaa
     2821 cggtcgcgcc ggtccacatt gatacagatc atgcatacgt aacgaaagaa gcagccgaac
     2881 aaaaagaagc caaacagata aaaacgcagc tcgcggacat ttgggaaatc ggaagtgaga
     2941 aaattacggt tcatatggaa ggcggggaga gtgtcggcaa tgaataaaaa cggattatgg
     3001 aatgtattga aaaagcagtt tcttccggga caaatgaagg acggcgaaaa gccgaagctg
     3061 accaaatatc attactttct attcgttttt gttctcggag tttcctttat gcttgtcagc
     3121 cagctgtttt cttcacctga gaaaacagaa aacgccaaaa cgataacggc cgtatcatcg
     3181 caacattccg cgggcagtaa agagaaaaca gctgaagtgt ttaaagcctc aaaatctgat
     3241 aaacctaaag actcgatcga tgactatgaa aaagaatacg aaaatcagct gaaagaaatt
     3301 cttgaaacaa tcattggtgt ggacgatgtc tcggttgtcg tgaatgtaga tgcaacgtcg
     3361 ctgaaagtat acgaaaaaaa caaatcaaac aaaaatacaa ccactgaaga aactgataaa
     3421 gaaggcggaa caagaagcgt tacagaccaa acatcggagg aagaaatcgt catgatcaaa
     3481 aacggcgata aagaaacacc tgtcgtcgtc caaacgaaaa aacctgatat acgcggtgta
     3541 ctcgttgttg ctcagggagt ggacaacgtt caaataaaac aaaccattat cgaagcggtg
     3601 acacgggtcc tggatgttcc aagccaccgg gttgcggttg cccctaaaaa aataaaggag
     3661 gattcataaa tgcttaaaaa acaaaccgtt tggctattaa caatgctcag tcttgtcgtg
     3721 gtgttaagcg tctactatat catgtcgccg gaaagcaaaa acgccgtgca gatgcaaagt
     3781 gaaaaaagcg cgtctgacag cggagaggtt gcaactgaaa aagcgcctgc caagcaagac
     3841 acgaaagaaa aaagcggtac agaaactgaa aaaggaaaag aagatggaac aaagggaacg
     3901 aaagattcat cagcagacaa ggaaacatcc gctgaagcca gtgaaaaagg aactgttgtt
     3961 acggaaacag ccgatgatga tctgtttaca acgtaccgtc ttgatttaga agatgccaga
     4021 agcaaagaaa gagaagagct gaatgccatt gtatcaagcg atgatgcaac agccaaggag
     4081 aaaagcgaag catacgataa aatgacggct ctcagtgaag tagaaggaac agaaaaacag
     4141 ctggaaacgc tgattaaaac acaaggttac gaggatgcgc ttgttaatgc tgaaggagat
     4201 aaaatcaata ttacagtcaa atcagacaaa cactccaaat cgaaggcgac agccattata
     4261 gaccttgtcg caaaagaaat caaaacaatg aaagatgtcg ctgtcacgtt tgaaccatcc
     4321 aagtaagaaa gaggaaaaag aagcccgcta aacaagcggg ctttttgcgt tgctgtcata
     4381 ttagagttga attcaaaagt ccgctcctgt aagatgaaca tagtatgtac ttttagtagt
     4441 aacctataaa aaaagaaatt tcatacatag gagtgcgatt gaatgttaaa tatcaaagaa
     4501 atccacgagc tgattaaagc aattgacgag tctacaattg acgaattcgt atatgaaaat
     4561 gaaggtgtat ccttaaaact gaaaaaacac gaagcaggca cggttcaagt tatgcagcag
     4621 gcaccggcag cacctgtaca agcacaggct ccgcaggcag ttcagccgca agcgcagcaa
     4681 gcagcggcac ctgcccaaga agtaccaaag caagatgaga atctgcataa aatcacttca
     4741 ccaatggtag gaacatttta tgcttcttca tcaccggaag ctggcccgta tgtaacagcc
     4801 ggttcaaaag taaatgaaaa cacagttgtc tgcattgtgg aagcgatgaa gcttttcaac
     4861 gaaatcgaag cagaagtgaa aggcgaaatc gttgaagtat tagtagaaaa cggccagctg
     4921 gtcgaatacg gacaacctct atttcttgta aaagcggagt aaggagactg aacatgatta
     4981 aaaagctatt gatcgccaac agaggagaaa ttgctgtcag aatcatcaga gcctgcagag
     5041 agctcggaat tgagactgtc gctgtttatt cagaagctga taaagatgcc cttcatgttc
     5101 aaatggccga tgaagctttt tgtatcggac cgaaagcatc aaaagacagc tatttaaacg
     5161 ttacaaatat tgtgagtgtt gcaaagctga ctggcacgga cgccattcat ccgggatacg
     5221 gatttttagc tgaaaatgct gatttcgctg aattatgtga agaagtgaat gtcacgtttg
     5281 tcggcccgag cgctgacgcc atttcaaaaa tgggaacaaa agacgttgcg cgggaaacga
     5341 tgaaacaggc cggcgtgcca atcgtaccgg gttcacaggg aattatagaa aatgtggaag
     5401 aagcggtttc gcttgctaat gaaattgggt atcctgtaat tataaaagcc accgcaggcg
     5461 gaggcggaaa aggaattagg gttgcccgca ctgaagagga attgattaat ggcattaaga
     5521 ttacacagca ggaagcggca actgcatttg gaaatccagg tgtatacatc gaaaaataca
     5581 tagaagattt tcgccacgtt gagatccaag tgcttgctga taactacgga aatacgatcc
     5641 atttgggcga acgcgactgc tcgatccaaa gacgcctgca aaagcttttg gaagaatcac
     5701 catctcctgc ccttgattca gaaatcaggg agcaaatggg agatgcagcg gtaaaggctg
     5761 caaaagcggt tggctataca ggtgctggaa cagttgaatt tatctatgac tacaatgaac
     5821 agcgctatta cttcatggaa atgaacacca gaattcaggt ggagcaccca gtcacagaaa
     5881 tggtgacggg aactgacctg atcaaggaac aaatcaaagt ggcatcagga atggaactga
     5941 gcctcaagca agaagatgtt gaatttgaag gctgggccat cgaatgccga atcaacgcag
     6001 aaaacccaag caaaaatttc atgccgtcac ctggtgaaat taaaatgtac ctgcctcctg
     6061 gcggtcttgg tgtccgtgtc gattcagctg cgtaccctgg ctattccatc ccaccgtact
     6121 atgacagcat gattgcaaag gtaatcacat acggaaaaac gagggatgaa gcgattgccc
     6181 gcatgaagcg cgcattgagc gaattcgtca tcgaaggcat tgagacaaca atccctttcc
     6241 atttaaaact gcttgaacac gaaacatttg tgagcggaga gtttaatacg aaatttttag
     6301 aaacatatga tgtaatgggc tcataatttt tacggaggtg aattgaatga aagacaacag
     6361 cttgcttaaa atggatcacg aagatacgca tttgggtaag gttgagattg caccggaggt
     6421 cattgaggtc attgccggca ttgcagcatc agaagttgat ggggttgccg aaatgcgcgg
     6481 aaactttgcg acaggcgtcg tcgagcgctt tggcaaagtg aatcatggca aaggtgtcaa
     6541 agtcgacctg gcggatgacg gaattacgat cgatgtatac tgtgtcgtta catttggcgt
     6601 ttcgattccg aaagttgcag catccgttca ggaaaacatt cgtcaaacct tattaaatat
     6661 gacgtctctt tcgattaacg agatcaatat tcacatcgtc ggcattcaat ttgacacaaa
     6721 agcccaagaa gtccaaatcg acgaagaaat gtaaatggct taacacgaaa ccaaggggag
     6781 ggcggccctt tggttttttt acacgttacc ctttatttca aagcatgaag aaagccggct
     6841 tacatagccg agtttcttca tgaacgtgaa atccgaataa tcatattaag gtgtgtgaaa
     6901 atattcggta atagggtaaa aaaaccttga tttcaatatg cggatacgaa aaaaatatgt
     6961 tatgatctct ttgtggctta acgacaagcg gataaagagg atcaaaggag aaagaaaatg
     7021 aaaagaagaa cagcaagaga aaaagctttg caggcactat ttcaaattga tgtcagcgat
     7081 attgcagtga atgaagccat agaacacgca ctggatgaag aaaaaacaga tcctttcttt
     7141 gaacagcttg tacacggggt attggaacac caagaccagc tggatgaaat gatctccaag
     7201 catctggtga attggaagct cgatcggatt gccaatgttg accgtgcgat tttgcgcctg
     7261 gcagcatatg aaatggcata tgccgaagac attccggtga atgtctccat gaacgaagcg
     7321 attgagctgg caaaacggtt tggtgatgac aaagcgacaa agtttgtaaa cggggttctt
     7381 tctaacatta aatctgatat tgaacattca taggaggaaa gaaaatgact gcaacaatca
     7441 tcgacggaaa agaaacggct agagaaaaac gcgaacaatt ggcaaaagag gtagaagagc
     7501 ttaaaaagca aggcgtcact cccggactgg cagttatttt gattggagat gatcctgctt
     7561 ctcactctta cgtgcgagga aagaaaaaag cggcagaaac aatgggaatg aatttcaagc
     7621 tcgatcaatt tgacagcagc ctcacagaag ctgaactgct ttccattatt gatcaatata
     7681 accaagaccc tgagtttcat ggcattctcg ttcagcttcc gctcccagac catatttctg
     7741 aaaaagcggt gatcgaacgt atctctcctg ataaagatgt agatggtttt catccgttaa
     7801 acgtagggaa aatgctgctt ggcgaagata cgtttcttcc ttgcacgcct catggaattg
     7861 ttgagctttt gaagaaaacc aatattgacc tttccggtaa agaggttgtt gtagtcggcc
     7921 gaagcaacat tgtcggcaaa cctgtcggcc agcttttatt aaatgaaaac gcgacggtta
     7981 cttactgtca ttcaagaaca gaaaatatta ctgaacatac gaaaaaagcg gacatcctgg
     8041 tggtggcagt cggcagagcc aacttcatca gtgcagacca gatcaaagag ggcgctgttg
     8101 tcattgacgt cggcgttaac cgtctggaaa acggaaagct ttgcggagac gttgaatttg
     8161 aaggggcaaa ggaaaaagcg tcattcatca cgccggttcc gggcggagta ggcccgatga
     8221 ccatcacgat gcttgcgcat aatactgtta aatctgcgaa acgtacgtta tcatagataa
     8281 ttggagatat tcacaggcga aatgtttacc cgccttgaat atgagcacga tacccgcttc
     8341 ttcaggctcc taaagccagg gcgggttttc tttagttatg gtgcaggaat gcttaggaga
     8401 ggagttttta gacatgggtg aagcagcgta tgtgaccgtc tcagcgctga caaagtatat
     8461 aaaacgaaaa ttcgatgtag atcctcacct tgaaaatatt tggattaaag gcgaattgtc
     8521 gaatgtaaag atacacacac gagggcatat ttatttcact ttaaaagacg aaaacgcaag
     8581 aatgcagtcg gtgatgttcg cgagacaaag cgagcgtctg ccttttaaac ctgaaaacgg
     8641 aatgaaagtg ctggtaagag gcggaatttc cgtatatgaa ccgagcggaa actatcaatt
     8701 atatgccaaa gaaatgcagc ctgacggggt tggagcgctt tatttagcgt acgaagaatt
     8761 aaaaaagaag cttgccggcg aaggtttatt tgacgaccgc tacaaaaaac aaatccccgc
     8821 atttccagcc acaatcgggg ttgtgacatc tccaacgggt gccgctgtca gagacgttat
     8881 tacaactcta aaaagaagat atccccttgt aaaagtcatt gttcttccag cgctcgtaca
     8941 aggtgaaaat gcgagcagat ccatcgttac gcgcattgaa gaggcaaatg aaaaagagat
     9001 ttgcgacgta ttaattgtcg ggagaggcgg cggttcgata gaagaactgt gggcattcaa
     9061 tgaagaaatt gtagcacgcg ccatctttgc ttccaatatt ccgattatat cggcagtcgg
     9121 acatgagacg gattttacga tcagtgattt tgtcgccgat atcagagccg cgacgccgac
     9181 aggagcagct gagattgctg tgcctcatac cactgattta atcgaacgca caaaaacagc
     9241 ggaagtcaga atgacaagag cgatgaagca gcacctcggc cagaaaaaag aacggattca
     9301 aacgctgcaa tcgtcctatg cctttcgttt tccaaagcgt ttgtatgcgc aaaaagagca
     9361 gcagtttgac ctcgcgtacc agcagtttca agcacagctg accgctcttt tagatcggaa
     9421 aagcagacag ctggagcgtg aaacgtacag attagaggca ctgcatcctc atgaacagct
     9481 gaaacaagcg agaacacgat accaggaaca aacaaatcag ctgagaaaaa atatgaatat
     9541 ccaaatgaag cagctgcatt cccaatttca aaccgttctt ggcaagctga atgcactaag
     9601 tcctcttcaa gtgatggaaa gaggatacag cttggcttat aaagaagata aactcattaa
     9661 aagtgtcagt caaatagaag agcaggaccg gcttgaagtc aagctgaagg atggcgtgct
     9721 gacctgtgaa gtattagaaa agagagggga agaaaaatga cagacgtgaa aaaaaatgaa
     9781 aacatgacat ttgaagaagc gatgaaaggg cttgagagca ttgtatcaaa gcttgaagag
     9841 ggagatgtgc ctctagagca agccattaac tatttccaag aaggcatggc tctgtcaaaa
     9901 atgtgccatg aaaagctgca aaaagtcgaa aagcaaatgg acttcatttt aaaagaagac
     9961 ggcgaactgg cacctttcag tgttcaggag gaagacgaag gtgacaaata aattaacgag
    10021 ctttcttgcg gaccggaaaa aaacaattga aaatcagctt tctgtctata cagaaaagct
    10081 tgatatgccg gactcattaa agaaatctat gctgtattct ctacaggccg gcggaaagcg
    10141 gttgcggcct ctgattgtac tggctgtttt aaacgcatat ggaaaaagcg aaaaagacgg
    10201 cattccggtg ggctgtgctg tcgaaatgat tcacacgtat tcgttaattc atgatgatct
    10261 tccatgcatg gatgatgacg atttgcgccg cgggaagccg acaaaccata aagtgtttgg
    10321 tgaagcgacg gcagtattag cgggtgacgg gctgctcaca gaaagcttta agctgattac
    10381 ctcccacgtg tcagacgagg tgtcagcaga aaagcgcctg cgccttgtga atgaactgat
    10441 ttcagcggca ggcaccgaag gcatggtcgg tgggcaagta gctgatatgg aagcggaaaa
    10501 ccgacaagtc acgcttgaag agctcgaatc cattcatgaa cggaaaactg ccaagctcct
    10561 tggcttttgt gtaatcgccg gtgctatttt ggctgatgcg cctgaggaag acattgaaac
    10621 actgcgtacc ttcagcagcc acattggaat cggatttcaa atcagagacg atattttaga
    10681 tttagaaggc agtgaagaga aaatcggcaa acgtgtcggc tcggatacca caaatgacaa
    10741 atcgacatac ccgtcgcttc tttcattgga aggggccaaa cataaattgg atgttcatat
    10801 aaaagaggcg aagcgattga tcggcggact ctctcttcaa aaagaccttt tatatgagct
    10861 ttgtgattta attgcggcaa gagatcacta aaacgatcct aatttgaagc ggctgcacga
    10921 ggtatggtaa aatgtaagca gtttatatga aaaatgaaaa ggaaaagcgc gtttgtcttt
    10981 ttttatgtct gagattattg tcagctcggc atgcaaaaga catgtatcat tgcagaaatt
    11041 catgctgaaa gtgagttgat ccgctttgga tcttttatca atacaggacc cgtcgttttt
    11101 aaaaaacatg tccattgatg aattagagaa attaagtgat gaaatccgtc agtttttaat
    11161 tacaagttta tccgcttccg gcggccacat cggcccaaac ttaggtgtcg tagagcttac
    11221 tattgctctg cataaggaat ttaacagccc gaaagacaaa tttttatggg atgtaggcca
    11281 tcaatcgtat gtccataagc tgctgacagg acgcggaaaa gaattcgcga cgcttcgcca
    11341 gtacaaaggg ctttgcggat ttccaaagcg gagtgaaagc gagcacgatg tttgggaaac
    11401 cgggcacagc tcgacttctc tgtcaggcgc gatgggaatg gcagctgccc gtgatattaa
    11461 aggaacggat gaatatatta ttccgatcat tggtgacggc gcgctgaccg gcggtatggc
    11521 gctcgaagcc cttaaccaca tcggcgacga gaaaaaagac atgattgtca tccttaatga
    11581 taatgaaatg agtattgcgc caaacgtcgg tgccattcac tctatgctcg gacggctccg
    11641 cactgcgggg aaataccagt gggtcaaaga tgagcttgaa tacttattta aaaagattcc
    11701 ggcagttggg ggcaagcttg ccgccacggc ggaacgagtc aaagacagcc tgaaatacat
    11761 gctcgtctcc ggaatgtttt tcgaggagct cggttttacg tatttgggcc cggtggacgg
    11821 acattcttat catgagctga ttgagaatct tcaatacgcc aaaaaaacga aaggccctgt
    11881 tcttctgcat gtcatcacga aaaaagggaa ggggtacaaa ccggctgaga ccgatacgat
    11941 tggaacatgg catggtaccg gaccatataa aattaatacc ggcgactttg taaagccgaa
    12001 agccgcagct ccttcgtgga gcggccttgt cagcggaact gtgcagcgaa tggcgcgcga
    12061 ggacggacgc attgtagcca ttacgccggc tatgcctgtc ggttcaaagc ttgaaggttt
    12121 cgcaaaggaa ttccctgacc ggatgttcga cgtaggaatc gcagaacagc atgccgcaac
    12181 gatggcggca gctatggcaa tgcagggtat gaagccgttt ttggcgattt actcaacctt
    12241 cctgcaaagg gcatatgacc aagttgttca tgacatttgc cgccaaaacg ccaatgtatt
    12301 tattggaatt gaccgtgcag gactcgttgg cgctgatgga gagacacatc aaggcgtgtt
    12361 tgatattgcg tttatgcgac acattccaaa catggtctta atgatgccga aagacgaaaa
    12421 tgaaggccag cacatggttc atacagcact tagctatgat gaaggcccga tagcgatgcg
    12481 ttttccgcgc ggaaacggac tcggcgtaaa aatggatgaa cagttgaaaa cgattccgat
    12541 cggtacgtgg gaggtgctgc gtccagggaa cgatgctgtc atcttaacat tcggcacaac
    12601 aatcgaaatg gcgattgaag cagccgaaga gctgcagaaa gaaggccttt ccgtgcgcgt
    12661 tgtgaatgcg cgttttatta agccgattga tgaaaagatg atgaagagta tcctaaaaga
    12721 aggcttgcca attttaacaa ttgaagaagc ggtcttagaa ggcggtttcg gaagctcgat
    12781 tttagaattc gctcatgatc aaggtgaata tcatactccg atcgacagaa tgggtatacc
    12841 tgatcggttt attgaacacg gaagcgtaac ggcgcttctt aaggaaattg gactgacaaa
    12901 acagcaggtg gcaaatcgta ttagattact gatgccgcca aagacacaca aaggaattgg
    12961 atcatgacgt caaagaaaga acgattagat gtattattag tggaaagagg gctggcggaa
    13021 acgcgtgaaa aagccaaaag agccattatg gcggggatcg tctattcaaa cgaaaaccgc
    13081 ttggacaagc ctggagaaaa aattgaccgc gaccttccgt taaccgttaa aggaaacccg
    13141 ctgaggtatg tgagcagggg cggcttaaag ctcgaaaaag cgttgaagga atttcccgtc
    13201 tctgtcaagg ataaaattat gattgatatt ggctcctcca ccggcggttt tacggactgc
    13261 gctttgcaaa atggagctaa acagtcatac gctgtggatg taggctataa tcagcttgcg
    13321 tggaagctca gacaggatga acgggtcgtc gtgatggaac ggacgaactt tcgttatgca
    13381 acaccggcag actttacaaa gggcatgccg gagtttgcca caattgatgt gtcctttatt
    13441 tcactgcggc tcatcctgcc tgtcctaagg actttgctcg taccgggcag cgactgcatg
    13501 gctctagtta agcctcagtt tgaagcggga cgggaatccg tcggcaaaaa agggattgtc
    13561 agagatccta aagtgcatgc tgatgtgctc aagcgaatga tcagtttttc tgccgctgaa
    13621 ggctatatct gtaaaggctt gtcattttct ccgataactg gaggagacgg aaatattgag
    13681 tttctccttc atttgcattg gccgggagag ggacaggatg gccaggagct gccggaagaa
    13741 gagatcatgc gcgttgtaga agaagcacat aagacgttaa aagaaaaaaa agcagatgta
    13801 ccggaataat agggcgctat tattcctttt ttctgcattc atgtacaatg tgcagagaat
    13861 catataacat aaaagaacag ataagcttgg aaatagaggt gcttacatga acaaaggcca
    13921 gaggcatatt aaaatcagag agatcattac aagcaatgaa atcgaaacgc aggatgaatt
    13981 ggtcgacatg ctaaagcagg atggatacaa agtaacgcag gccacggtat cacgggatat
    14041 taaagaactt caccttgtaa aagtgcctac aaataatggt tcttacaaat acagtcttcc
    14101 ggcggaccag cgtttcaatc cgctgtcaaa gctaaagcgg gcattgatgg acgcatttgt
    14161 gaaaatagac tcagcaagcc atatgattgt gctgaaaacg atgccgggca atgcccaggc
    14221 aatcggggcg ctgatggaca atttggactg ggatgaaatg atggggacca tttgcggaga
    14281 tgatacgatt ttaattattt gccggactcc tgaagataca gaaggcgtaa aaaacaggct
    14341 ccttgaactg ctgtaacaga aaatctaaca aagataagag gtgtaatgct gtttgttagc
    14401 tgaactatcg attaaaaact ttgccattat tgaggaactg acggtttctt ttgaacgcgg
    14461 gcttacggtt ttaacaggag aaaccggagc cggcaaatcc attatcatag atgccatttc
    14521 tcttttagtc ggaggccgcg gatcatctga atttgttaga tatggggaag caaaagccga
    14581 acttgaaggg ctgtttctgt tggagagcgg ccatcctgtt ttaggcgtat gcgctgagca
    14641 gggaatcgac gtttcagacg aaatgatcgt catgagaagg gatatcagca cgagcgggaa
    14701 aagcgtttgc cgtgtcaatg gcaagcttgt cacgattgct tcgctaagag agatcggcag
    14761 gcttttatta gatattcacg ggcagcacga taaccagctg ttaatggaag acgaaaatca
    14821 tctccagctt ttggacaagt ttgccggggc cgaagtggaa agcgcgctta aaacgtatca
    14881 ggaagggtac cagcggtata tgaagctgct caaaaagctt aagcagcttt ctgaaagcga
    14941 acaggaaatg gcccatcgtc ttgatcttat tcaatttcag ctcgaagaaa tcgaatcggc
    15001 aaagcttgag cttaacgaag atgaacagct ccaagaagag cgcaagcaaa tttcaaactt
    15061 tgagaagata tatgagtcgc tgcaaaatgc atataacgcg cttcgcagtg agcagggcgg
    15121 attggactgg gttggaatgg catcagcgca gcttgaagat atatctgata taaacgaacc
    15181 gctgaaaaaa atgtctgaaa gtgtttcgaa ctcctactat ttgcttgagg atgccacatt
    15241 tcagatgaga aatatgctgg atgagcttga atttgatccg gaacgcctga actatattga
    15301 gacgcgactt aatgaaatca aacagctgaa acgaaaatac ggtgccactg ttgaagacat
    15361 tttggaatat gcttctaaaa ttgaagaaga gattgaccaa attgaaaaca gggacagcca
    15421 ccttcaaagc ttgaaaaagg agcttgactc cgtcggcaaa gatgtcgcag tggaagcggc
    15481 aaatgtgtca caaatccgaa aaacatgggc gaaaaagctg gctgatgaga ttcatcggga
    15541 attaaaaagc ctgtacatgg aaaaatcaac ttttgatacg gaatttaagg tcagaacagc
    15601 gtcacgcaat gaagaggcgc cgcttgtaaa cggccagccc gttcagctga ctgaacaagg
    15661 gattgacctg gtgaagtttt taatttcaac caatacaggc gagccgctga aatccctttc
    15721 gaaagtcgct tcaggtggag agctgtcacg ggtgatgctt gccataaaaa gcattttttc
    15781 ctcacaacag gatgtgacat cgatcatttt tgacgaggtt gataccggtg taagcggcag
    15841 ggtcgcacag gcaattgctg agaagatcca taaggtgtca ataggatcac aagtgctgtg
    15901 cattacacac ctgcctcagg tggctgccat ggccgatacg catctttata ttgcgaagga
    15961 gttaaaagac ggtagaacga cgacacgtgt caagccgctg tctaagcagg aaaaggtagc
    16021 ggaaatcggg cgcatgattg caggtgtcga ggtaaccgat ttaacgaaac gccatgcgaa
    16081 agaactttta aaacaagcgg atcaagtcaa aacaactggg taagctgcgc gagaagcgca
    16141 gcttattttt ttcgtgcaca tccattcgtt catcagtata tccaatgttt ttcttcatat
    16201 gacagttata aataagccgt cagaaggcaa aattaaatga tgtagcagca agtcataaag
    16261 aaggtgtggg ataggagcga ggagagtgaa gtagtgaatg cccgataaca tcagaaaagc
    16321 agtaggttta attctccttg tttcgttatt aagtgtaggt ttatgcaaac cgctaaaaga
    16381 atatttactg attccaacgc aaatgagagt atttgaaacc caaacacaag cgattgaaac
    16441 gagtttatcg gtaaacgctc agacatcaga atcctcagaa gcgtttacag taaagaaaga
    16501 tccgcatgaa atcaaggtga cgggcaaaaa atcaggtgag tcagaattgg tatatgatct
    16561 tgccggattt ccaattaaaa aaacaaaagt gcatgttctt cctgatttaa aggttatacc
    16621 tggcggacaa tcaatcggtg taaaacttca ttccgtcggt gttcttgtcg tcggatttca
    16681 tcaaatcaat acaagtgaag gcaaaaaatc tccgggagaa acggccggaa ttgaagcggg
    16741 cgacatcatt attgagatga atggacagaa aattgaaaaa atgaatgatg tagccccatt
    16801 tattcaaaag gctgggaaaa ctggtgaatc tttagattta ctgatcaaac gtgataaaca
    16861 gaaaatcaaa acgaagctga tcccagaaaa ggatgaagga gaaggcaaat acagaatcgg
    16921 gttatatatc agagattctg ctgccggcat cggcactatg accttttatg aaccgaaaac
    16981 aaaaaaatac ggagcacttg gccacgtgat ttccgatatg gacacaaaga aaccaattgt
    17041 agtggagaat ggagaaattg ttaaatccac tgtaacatca attgaaaaag ggacaggcgg
    17101 taatccggga gaaaaactgg cgcgattttc ctcagaacgc aaaacgatcg gggatattaa
    17161 cagaaacggc ccgtttggga ttttcggcac gctgcatcag ccgattcaaa acaacatatc
    17221 agatcaagca ttgccggttg cgttttctac cgaagtcaaa aaagggccgg ctgaaatttt
    17281 aaccgtcatt gatgatgaca aagtagaaaa attcgatatt gaaatcgtca gcacaacgcc
    17341 gcaaaaattc cctgcgacaa aaggaatggt gttgaaaatt accgatccaa ggctgttgaa
    17401 agaaacagga ggcatcgtac aggggatgag cggaagcccg attattcaaa acggaaaagt
    17461 gatcggtgct gtcacccatg tatttgtaaa tgacccgaca agcggttacg gtgttcatat
    17521 tgaatggatg ctgtcagaag caggaatcga tatttacgga aaagaaaaag caagctgact
    17581 gccggagttt ccggcagttt ttttatcgtt taggaaatta taaaattctg gacttgtgga
    17641 taactgttcg gtaaaatgtt cgtataaata taacggagtt cgaaaatgag tcaggctggc
    17701 agtggagtta ttaaacgaat attaaaagac cactttgatg gattttggag aatgcactct
    17761 gatctttttc cgaaatccta tcgtgaagat ataaaagaaa ctgtggaaaa agcaatcaga
    17821 tgcggtacta aagatttagg atatgctcga tatgaatgct tagggtgtga tggagagcct
    17881 a
//
