LOCUS       NZ_AP019791            20975 bp    DNA     circular CON 25-APR-2024
DEFINITION  Rubrobacter xylanophilus strain AA3-22 chromosome, complete genome.
ACCESSION   NZ_AP019791
VERSION     NZ_AP019791.1
KEYWORDS    RefSeq.
SOURCE      Rubrobacter xylanophilus
  ORGANISM  Rubrobacter xylanophilus
            Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales;
            Rubrobacteraceae; Rubrobacter.
REFERENCE   1
  AUTHORS   Tomariguchi,N. and Miyazaki,K.
  TITLE     Complete Genome Sequence of Rubrobacter xylanophilus Strain AA3-22,
            Isolated from Arima Onsen in Japan
  JOURNAL   Microbiol Resour Announc 8 (34), e00818-19 (2019)
   PUBMED   31439702
  REMARK    DOI:10.1128/MRA.00818-19 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022875)
  AUTHORS   Miyazaki,K. and Tomariguchi,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2019) Contact:Kentaro Miyazaki National Institute
            of Advanced Industrial Science and Technology; 1-1-1 Higashi,
            Tsukuba 305-8566, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Coverage                   :: 758x
            Sequencing Technology             :: NovaSeq6000; GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007164525.1-RS_2024_04_25
            Annotation Date                   :: 04/25/2024 02:58:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,085
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 3,015
            CDSs (with protein)               :: 3,015
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 17
            CDSs (without protein)            :: 17
            Pseudo Genes (ambiguous residues) :: 0 of 17
            Pseudo Genes (frameshifted)       :: 5 of 17
            Pseudo Genes (incomplete)         :: 9 of 17
            Pseudo Genes (internal stop)      :: 4 of 17
            Pseudo Genes (multiple problems)  :: 1 of 17
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:10:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2831996
            Orig. end                         :: 2852971
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP019791.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10975)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(437..1390)
                     /locus_tag="RxyAA322_RS14335"
                     /old_locus_tag="RxyAA322_28730"
     CDS             complement(437..1390)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563476.1"
                     /locus_tag="RxyAA322_RS14335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28730"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_143528955.1"
                     /transl_table=11
                     /translation="MTKIGYFLSCEEWGPRELLEQAEMAEAAGFEGLWISDHFHPWNSE
                     QGNSPFVWSVIGGLSRVTSLPVTTAVTCPTIRIHPAIIAQAAATSAVMLEGRFVLGVGS
                     GENLNEHILGDRWPPADVRLEMLEEAVHLMRLLWEGGVKDFHGNHYTVENARLYTLPEE
                     PPPVYVSGFGPKSVRLAARIGDGYCSTIPDAGLVSLFRSSGGGEKPAQAGMKVCWSEEE
                     SRARKTAHRLWPNEQLPGELAQELPTPRHFEQASELVTEEMVAAEVPCGPDPELHLRSI
                     RRYIEAGYDEIYIQQIGPEQEGFFRFYETEILPELP"
     gene            complement(1462..1614)
                     /locus_tag="RxyAA322_RS15925"
                     /old_locus_tag="RxyAA322_28740"
     CDS             complement(1462..1614)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS15925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_28740"
                     /product="hypothetical protein"
                     /protein_id="WP_244299783.1"
                     /transl_table=11
                     /translation="MRRAIFTHCGTEIVAGNEERVAEEIRRLGQKRGVEASFARDGIKI
                     ELAGG"
     gene            complement(1623..1862)
                     /locus_tag="RxyAA322_RS15930"
                     /old_locus_tag="RxyAA322_28750"
     CDS             complement(1623..1862)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS15930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_28750"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_233451814.1"
                     /transl_table=11
                     /translation="MEPRRKHSTRAPAVGYRISTGEAAVFYAPDMVYIHGRGEALFGVL
                     LYVGDGASVTRPLVHRRGEALSGTPPSGPGSPGA"
     gene            complement(2123..3847)
                     /gene="polX"
                     /locus_tag="RxyAA322_RS14345"
                     /old_locus_tag="RxyAA322_28760"
     CDS             complement(2123..3847)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="polX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563478.1"
                     /locus_tag="RxyAA322_RS14345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28760"
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="WP_143528956.1"
                     /transl_table=11
                     /translation="MPIHNAEIAAILHEVADLLEIEGENPFRVRAYREAARTVENHPRS
                     LAEMVGKGESLTRLPGIGEDLAGKIREIVRTGTLRQTEELRERVPPGLRSLLGVPGLGP
                     RRVRELHRRLGITSAAELERAAREGRVRRLPGFGEKTERNILEALSRGETPRRFRLASA
                     EPAARALEEHLRGCAAVREVVVAGSFRRRKETVGDLDVVACSHDGRRVVEHFVAFGGVE
                     RVVSRGGTRSSVVLKDGLEVDLRVVPEESFGAALLYFTGAQPHHVALRDMALQKKLKLN
                     EYGLFRGEERVAGRTEAEVYGALGLRYIEPELREYRGEIEAASEDALPELLTREDIRGD
                     LHSHTTATDGRNSLEEMARAAEERGYEYLAITDHSRRLRVARGLDERRLREQMEQIDRL
                     NEELEGITLLKGAEVDILEDGSLDLPDGVLRELDVVICSVHHKLRLPEREQTRRVLRAL
                     ANPNVNILAHPTGRLIGRREPCELDVERVMEAAVERGCILELNANPERLDLNDAHCRLA
                     KEMGVRIAVSTDAHGTNELANIRFGVGQARRGWLEREDVVNTRSLGELRRLLRREGA"
     gene            complement(3849..4586)
                     /locus_tag="RxyAA322_RS14350"
                     /old_locus_tag="RxyAA322_28770"
     CDS             complement(3849..4586)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563479.1"
                     /locus_tag="RxyAA322_RS14350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28770"
                     /product="DUF72 domain-containing protein"
                     /protein_id="WP_143528957.1"
                     /transl_table=11
                     /translation="MRAVGGRVHIGTSGWHYDHWRGSFYPPGLPASRFLEHYAAHFATA
                     EINNSFYRLPEEETLARWRDRTPDGFVFAAKASRYLTHMKKLREPEEPLQRLFGRLETL
                     GEKLGPVLFQLPPRWRANQKRLEGLLRALPPGRRCAFEFRDASWFNQKIYRLLREHGAA
                     LCVYDLAGQTSPPVLTAGFAYVRLHGPEGPYRGCYGERRLAGWAGLLRGWAGEGVEVYC
                     YFDNDEAGYAPRDAGRLKKMMEV"
     gene            complement(4650..5111)
                     /locus_tag="RxyAA322_RS14355"
                     /old_locus_tag="RxyAA322_28780"
     CDS             complement(4650..5111)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020022.4"
                     /locus_tag="RxyAA322_RS14355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28780"
                     /product="ATP-binding protein"
                     /protein_id="WP_143528958.1"
                     /transl_table=11
                     /translation="MGSERDTGARLALMCGLPKSGKTTYARRLQSHGWVRVCPDEIRRA
                     LHGRGHYPPAEPLVWANAELSVRALLLGGHRVVLDATNTTRHRRAPWLRLARELGVPVC
                     AYVLKTPKEECLRRNQTSEEPVPPEVIDRMARQWEEVNEDGLEVHPVEG"
     gene            5219..5881
                     /locus_tag="RxyAA322_RS14360"
                     /old_locus_tag="RxyAA322_28790"
     CDS             5219..5881
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563481.1"
                     /locus_tag="RxyAA322_RS14360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28790"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_143528959.1"
                     /transl_table=11
                     /translation="MCGRYTLATPVGRVAEQFGAEGPLPEIPPSYNVAPGRGVAAVVQE
                     GGRRRLEVLRWGLVPPWAEDPRVGDRMINARAETAASKPSFRRAFRERRCLIPADGFYE
                     WRRLDGGKQPYYVRRRDRAPFAFAGLWEVWRGEEGELRSCTILTTRANRLLSEIHDRMP
                     VIVPRDLYGLWLEAEGEREELDAVLRPYPEEELEAYPVSRLVNSPANDDPRCIEPAA"
     gene            5881..6789
                     /locus_tag="RxyAA322_RS14365"
                     /old_locus_tag="RxyAA322_28800"
     CDS             5881..6789
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563482.1"
                     /locus_tag="RxyAA322_RS14365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28800"
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="WP_143528960.1"
                     /transl_table=11
                     /translation="MRPVQPAPEVAEALQEGRPVVALESTLISHGLPRPDNLRVARALE
                     EEIRREGAVPATVGVVEGVARVGLGPEELELLASGEVPKLSARDLPAAAAKGVSGATTV
                     AATAHLAALCGIKLFATGGLGGVHRGARESWDVSADLAALSRTPVAVVCSGVKSILDVP
                     ATLEQLETLGVPVVGFRSRAFAGFYLSDSGCTLAWSVEDEREAAALIRALPGLGLGCGV
                     VISNPLPPEEQLDPGLHERVLRSGLEELARRGVSGKEVTPFLLEHFRERTGGESLRANE
                     RLVLRNGRLAARIARRLCEER"
     gene            6786..7697
                     /locus_tag="RxyAA322_RS14370"
                     /old_locus_tag="RxyAA322_28810"
     CDS             6786..7697
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.4"
                     /locus_tag="RxyAA322_RS14370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28810"
                     /product="sugar kinase"
                     /protein_id="WP_143528961.1"
                     /transl_table=11
                     /translation="MSAPRAVVVGDVLYDMVARIEGELPIGDDSFVPIRDAPGGSAANV
                     AAWLAILGVETHLVGRVGDDPVGEHLEAGLREAGVRTHLFRDASLPTGKVFVLVDGSGE
                     RTMITDRGAGEALGLQDLPLELFASGGHLHLTGYLFSGGSRRAVALEALRLARRASMSV
                     SVDPSSVTLLRAVGPERFLRWTAGADLAFPNLAEGALLSGRKEPEEVFRVLLGHYRAVV
                     LKLGPEGALYAGRDGARERQTAPRVARPDATGAGDALCAGFLAARLRGRPPAEALRMGV
                     RLASRIAGHTGARGFHAGRGPC"
     gene            7730..10000
                     /locus_tag="RxyAA322_RS14375"
                     /old_locus_tag="RxyAA322_28820"
     CDS             7730..10000
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563484.1"
                     /locus_tag="RxyAA322_RS14375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28820"
                     /product="GGDEF domain-containing phosphodiesterase"
                     /protein_id="WP_143528962.1"
                     /transl_table=11
                     /translation="MRSACDREGTAAGKGPEPDDLRLLQFLGWVVPLVFGFAALAGVAA
                     AVFSDAGLLAAGVILLAYGGLLLVARRRVGIGGRGSAVWTICVGLLLAALLMSAVQPGW
                     LAVLAITPLISVAVALPYVRGGDLLRLILLAWLTVVVMAVLSRTLRPLSEPPGWFSDVF
                     AASALAAASAVVLLLLWQFSSRLNETLAQTRAAEERYALVERGVNDGLWDWDLRRDRIY
                     YSSRWKEMLGYREDEIGAGPEEWFRRVHPEDRKRLLQEVGDHLRGRREHLNVEYRIRHR
                     DGSYRWMLTRGLAVRDGEGNPVRMAGSQTDITRRKRAEEELLYEASHDALTGLPNRAFF
                     MERLGEALRRARSEEGFRLAILFVDLDRFKMINDSLGHTIGDRLLVAAAGRLRECLRPQ
                     DTLARLGGDEFTVLLEDVSGEEAAAVADRLLERLRTPFYLDGYELFTAASVGVVLGGRE
                     YASPEDLLRDADIAMYRAKAVGGGRKGIFEAGMHTRAVELFRLENELRRAIERREFTTH
                     YQPIISLKTGLISGFEALVRWRHPERGLVLPDEFIPVVEETGLILLLELSVMREACARL
                     AAWQKRFPDHRPLTVSVNLSRNQLVRSELPEQIERTLLETGLDARSLRLEVTEGALMEN
                     VDSAVATLSRLRDMNIRVHIDDFGMGYSSLSVLHQLPIDALKVDRSFVGRMDGVGGDAE
                     IVQTIVTLAHNLGLDVIAEGVEREEHLRQLRKLGCDYAQGFLFSEPLDAENAQRLISSY
                     RRW"
     gene            complement(10001..10975)
                     /locus_tag="RxyAA322_RS14380"
                     /old_locus_tag="RxyAA322_28830"
     CDS             complement(10001..10975)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="RxyAA322_RS14380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28830"
                     /product="hypothetical protein"
                     /protein_id="WP_143528963.1"
                     /sec_met_domain="T1TS (E-value: 3.2e-88, bitscore: 294.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSSKNGMVRVPRLRCPFPAAMNPHADGVHRETVEWAEGFGLLAS
                     GESRRMVRDTQIGRLAGRFHPCAGREELRLISDWCAWMFLRDDLADDPAYFRHPERLAA
                     LDAAFLDILSGRISGEEHGPFGRALRDLRERLLPKVPGPLWLRRFLRSVEEHFESTLWE
                     ATNRARGVTPDLATYVRMRPITGGMHVDTDFIEVTSGIYLPPEVHRERVVSSLTEASNN
                     VVCWANDIISLAKERSRGDVHNLVLVLCESRRLPLGEAVAEAVRMYEAEVRRFVRLEKE
                     LPSFGPAVDDNLRRYVWVLKTRMRGNLEWTYESARYRVGAASP"
     misc_feature    10959..10975
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.61"
                     /tool="antismash"
     gene            complement(11087..12037)
                     /locus_tag="RxyAA322_RS14385"
                     /old_locus_tag="RxyAA322_28840"
     CDS             complement(11087..12037)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563486.1"
                     /locus_tag="RxyAA322_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28840"
                     /product="aldo/keto reductase"
                     /protein_id="WP_143528964.1"
                     /transl_table=11
                     /translation="MNGYERAPLAIRLGIEPLGVGAWAWGTRRLWGYGSGYGLAEVTAA
                     LHESLAAGVRLVDTAEIYGNGESERIIGSVLREGGLPARPVLATKFAPYPYRLSPRSLL
                     SALDGSLRRLGVESVDLYQIHWYSPIPPPDRLLDALAEAVKEGKARHVGVSNYGAEAMR
                     RAFERLDARGVPLASNQVEYSLLHRTPETDGTLEACRELNVTLIAYSPLAQGLLTGKYG
                     PGSRPPGLVRRLGRAFGERNLRRVQPVVGILREIGERHGKSPAQVALNWLLAQGTLPIP
                     GAKDASQARQNAGALGWSLSPEEKERLDLATLGWR"
     gene            complement(12037..13038)
                     /locus_tag="RxyAA322_RS14390"
                     /old_locus_tag="RxyAA322_28850"
     CDS             complement(12037..13038)
                     /NRPS_PKS="Domain: Abhydrolase_1 (57-223). E-value:
                     7.6e-18. Score: 56.9. Matches aSDomain:
                     nrpspksdomains_RxyAA322_RS14390_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="RxyAA322_RS14390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28850"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_143528965.1"
                     /sec_met_domain="PF00561 (E-value: 1.8e-11, bitscore: 41.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.3e-18, bitscore:
                     65.1, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLMRAALTTAGTLGALHALNRHLERSGGPPRTALGGERRRYRWK
                     GGEIAYSVAGEGPPLLLVHGIYAGASSLEFRRNFGPLSRHFTVYAPDLLGCGASEKPRR
                     RYAPEDVTSQIEDFVREEIQRPTHLVASSLSAALALPAAVRSPRLFRSLVLICPTGLGT
                     LDRPSGRLGEAVYRLLVSPLLGDLLYHALVSHRGIRLYLERMAYHDPSRVTEEIVEDHY
                     RVSHGPNAKFLPAAFVAGKLNQPALPCWTQLRQRVMVCWGREARTPPPAELDAFLRYNP
                     RTAPRIFRDAALLPHDERAEDFNREVADFVSAGRIKAPGSNGKRPTEKGNQP"
     aSDomain        complement(12370..12867)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RxyAA322_RS14390_Abhydrolase_1.1
                     "
                     /evalue="7.60E-18"
                     /label="RxyAA322_RS14390_Abhydrolase_1.1"
                     /locus_tag="RxyAA322_RS14390"
                     /protein_end="223"
                     /protein_start="57"
                     /score="56.9"
                     /tool="antismash"
                     /translation="PPLLLVHGIYAGASSLEFRRNFGPLSRHFTVYAPDLLGCGASEKP
                     RRRYAPEDVTSQIEDFVREEIQRPTHLVASSLSAALALPAAVRSPRLFRSLVLICPTGL
                     GTLDRPSGRLGEAVYRLLVSPLLGDLLYHALVSHRGIRLYLERMAYHDPSRVTEEIVED
                     HYR"
     gene            complement(13100..14764)
                     /locus_tag="RxyAA322_RS14395"
                     /old_locus_tag="RxyAA322_28860"
     CDS             complement(13100..14764)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012471.4"
                     /locus_tag="RxyAA322_RS14395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28860"
                     /product="M14 family metallopeptidase"
                     /protein_id="WP_143528966.1"
                     /transl_table=11
                     /translation="MRFDRYLDHAELTAALHGLAREHPELCRVEEVGRSYEGREIWLAE
                     ITNTATGPADLKPAFWVDGNTHAGEVTGSMAALYLIHRLLTGYSSDPGMRRLLDAQAFY
                     VLPRLSPDGAERYLKTPHTLRATLRPWPEPEEEPGLHPEDVDGDGEILHMRVEDEHGEW
                     KVSETDPRLMVRRRPDETGGTYYRLYREGTFRDYDGFERRIARPLHGLDMNRQYPYRWQ
                     GEHEQPGAGPYPLSEPESRAHVEALLRRRNVFGIHTYHTFCGAILRPYSDRDDLEMPDH
                     DLAVYRALGDRGTELTGYPNLSVYHGFRYDPRKTISGAFDDWAYDAYGVFAFTIELWSV
                     ARAAGVKVEDFIGFFRDPPEEALLRILAWNDRELDGEGFERWRPFDHPQLGRVEIGGWR
                     TKFTFQNPPPHLLEAECERAFRFALAHARTAPLLDGRLSAKTLPGGLRRLELIVENTGY
                     LPTSVTRVAEERKLAKPPEARLELPEGAELVSGERVVELGHLAGRSALEGSSWKSPAFF
                     DGLPSAYARRVVWVVRGEGPVEVEVKSERAGTLRLRA"
     misc_feature    14756..14771
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            14940..16298
                     /locus_tag="RxyAA322_RS14400"
                     /old_locus_tag="RxyAA322_28870"
     CDS             14940..16298
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="RxyAA322_RS14400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28870"
                     /product="protein kinase"
                     /protein_id="WP_143528967.1"
                     /sec_met_domain="Pkinase (E-value: 4.8e-56, bitscore:
                     187.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPARREAAGGGRELETSAKTVFGDRYVVREKLGSGGMAVVYRAED
                     TLLGRDVAIKTLHRRYAEVPAFRRRFRQEARAMASLDHQNIVKVYDISPDGDAPFIVEE
                     YVGGRDLGSLLARQRGGRLEESFAVRVAEQLLKALAYAHWRGVIHRDIKPSNILITPGG
                     IVKVADFGIARLVEDEGEGGGEIIGSARYMSPEQLRGLEATPRSDLYSVGVLLYHCLTG
                     RPPFTGDVKSLARQHLGEVPRPPRELNRGLSPQMEAVILRAMAKDPEDRYPSATAMLDE
                     IQEGVRHRARSGTREMPRRRTRRGRLALVSTLAVLLLGGGTAVGASGLAGYVDLSPRSS
                     VQQPVVGAAEPLRSAPPGIPETSREEAARNAPLVPVPDVRPYFDYSAREILVNRGFKVR
                     IVYAYREGYANRGVAWGTDPPAGTLVPAGSTVTVYSTPKDLYQPQIRTTGASP"
     gene            complement(16302..16670)
                     /locus_tag="RxyAA322_RS14405"
                     /old_locus_tag="RxyAA322_28880"
     CDS             complement(16302..16670)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF021221.4"
                     /locus_tag="RxyAA322_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28880"
                     /product="DUF4870 domain-containing protein"
                     /protein_id="WP_206751777.1"
                     /transl_table=11
                     /translation="MSPEDERTWSAMAHLSALAGLVGLMPVGALVIWLVYRDRSPRVGF
                     HALQALLYQAVWLAIWVVGAISGVLFVLFTLGLGLILVLPLAVAAWVLPMAHGCYAAYR
                     VSRGEDYRYPVVGRWVGP"
     gene            complement(16761..17252)
                     /locus_tag="RxyAA322_RS14410"
                     /old_locus_tag="RxyAA322_28890"
     CDS             complement(16761..17252)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_28890"
                     /product="hypothetical protein"
                     /protein_id="WP_143528969.1"
                     /transl_table=11
                     /translation="MTPLEKPWSGLSRELGGRFAARGLPPAGFSLFRTDGREFGHLRME
                     GPGGARLTAAKTSATVERKPGERYAMLWEDVEALSAEGPPKGFWMMEPGGEIWESNLRL
                     LRNAATARGPGGCARVEGDLVGMRYDARFEGECGLPVALFLLYRLASVRSRAFLLRTRG
                     "
     gene            17340..17693
                     /locus_tag="RxyAA322_RS14415"
                     /old_locus_tag="RxyAA322_28900"
     CDS             17340..17693
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS14415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_28900"
                     /product="hypothetical protein"
                     /protein_id="WP_143528970.1"
                     /transl_table=11
                     /translation="MELKNKEELRNEILQSWLRDAWVYPVEGPDRKIYLRLTPGGRLKM
                     RKKIGEMERSLGVSGPELVRQDEAGTLPLDRDRLELAMMVRAYTSERRFIESSGGSLGS
                     PAVTLEEGDEGSS"
     gene            complement(17690..18418)
                     /locus_tag="RxyAA322_RS14420"
                     /old_locus_tag="RxyAA322_28910"
     CDS             complement(17690..18418)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563492.1"
                     /locus_tag="RxyAA322_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28910"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_143528971.1"
                     /transl_table=11
                     /translation="MPDWWPPVEINPQDLSLERLVGYYLDFGTVLENSGPLLRGLAVTL
                     SLAALAEVVGIVLGLFLALLKISRSRLLSLPAQIYIDVFRGTPLLVQITIIYFTTAAVG
                     VRFTSLFFAGLTALALNSSAYVAEIFRAGIQSIDKGQMEAGRASGLTYAQTMRYIIVPQ
                     AFRRVIPPLTNEFVTLIKDTSLVSVIGLAELLRAARVLQSATFNGTPLIAAALIYLAIC
                     LPLIYLTNVLERRLNRRTAA"
     gene            complement(18439..19272)
                     /locus_tag="RxyAA322_RS14425"
                     /old_locus_tag="RxyAA322_28920"
     CDS             complement(18439..19272)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /locus_tag="RxyAA322_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28920"
                     /product="basic amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_143528972.1"
                     /transl_table=11
                     /translation="MSRRKVERNFVTLALVVAALFLVAACGGGGGGGEQTAGGGGEGTT
                     GMETGRTVTVASDIAYRPFEFYRNGEPVGFDIDLMREIGRRAGFTPEFQNVTFDGIIPG
                     LGSNLYDAAISAITITEERRQQVDFSEPYFNADQSLLVRSDSEIRSVDDLGQATVGVQI
                     GTTGANKANQFQQQGRIAEVRTFDTIEDAFTALENGQVDAVINDLPVSQDKANTSDGRL
                     EVVQVIPTGEQYGIAFPKGSNLVGPVNRALREMKSDGTYAEIYEKWIGRKPEEIP"
     gene            complement(19402..20136)
                     /locus_tag="RxyAA322_RS14430"
                     /old_locus_tag="RxyAA322_28930"
     CDS             complement(19402..20136)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563494.1"
                     /locus_tag="RxyAA322_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28930"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_197735501.1"
                     /transl_table=11
                     /translation="MSIIEFRNVSKSFGDFEVLKDIDFSVEEGEVVVIIGPSGSGKSTL
                     LRCINALEDISSGELVVDGIRVHDEKADLNRLRTEIGFVFQQFNLYPHMTVAQNIMLAP
                     MKVRGLSRKEAEERCMRLLERVGIPEQANKYPENLSGGQQQRVAIARALAMEPKIMLFD
                     EPTSALDPEMINEVLEVMVDLARGGMTMVVVTHEMGFARRVADRVVFMDEGRILEEGTP
                     EHFFENPENERARRFLDRILHM"
     gene            20240..20887
                     /locus_tag="RxyAA322_RS14435"
                     /old_locus_tag="RxyAA322_28940"
     CDS             20240..20887
                     /EC_number="3.2.2.27"
                     /GO_function="GO:0004844 - uracil DNA N-glycosylase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011563495.1"
                     /locus_tag="RxyAA322_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_28940"
                     /product="uracil-DNA glycosylase"
                     /protein_id="WP_143528973.1"
                     /transl_table=11
                     /translation="METLFDAVEGGENREERLAELARQVSVCTRCDLSRSRTNTVFGTG
                     DPYSPLMLVGEGPGENEDATGLPFVGRAGKLLDNILAAVNLSREQVYITNIVKCRAAVE
                     ENGRLRNRQPRTAEINACNPYLQAQIEAIKPEIILCLGGPAAKTIIDRDFRITRDRGKW
                     YDVGGIRAMATFHPAYILRQSGEELVRTKRLVWKDIQNVYAEYQRAMEHRGV"
ORIGIN
        1 gggccgggat cgtcgtcttc tccaaccact ggggccccaa catggtcgag cgcccgcccg
       61 agcacttccg acgcttcgcc cgggcggtgg tggaccgggg ggccgacgtc tactacgggc
      121 acagcgccca tgtcttccag ggcgtcgagg tctaccgggg caggcccatc ctctacgaca
      181 ccggggactt cgtcgacgac tacgccgtgg actcccacct gcgcaacgac cggtcgttcc
      241 tcttccgggt cgaggtgggc gaggaggggc tgctgcgcag gctcgagctc ttcccggtcc
      301 ggctccccta cgcccgggtg cggcgggcgg tcggggagga ggccgaggcc atcatggggc
      361 ggatggagcg tctctcggcc gagatgggca cccgtttcga gcgcgcgggg gaccggctgc
      421 tcctccgggg gccctgctag ggaagctccg gcaggatctc cgtctcgtag aaccggaaga
      481 agccctcctg ctccgggccg atctgctgga tgtagatctc gtcgtagccc gcctcgatgt
      541 agcggcggat agagcgcagg tgcagctccg ggtccggacc gcagggcacc tccgcggcca
      601 ccatctcctc ggtgaccagc tcgctggcct gctcgaagtg ccggggggtg ggcagctcct
      661 gcgccagctc gcccgggagc tgctcgttcg gccacagccg gtgggccgtc ttgcgcgccc
      721 gcgactcctc ctcgctccag cagaccttca tcccggcctg ggcgggcttc tctccgccgc
      781 ccgaggagcg aaacagcgag accagcccgg cgtccgggat ggtgctgcag tagccgtcgc
      841 cgatcctggc ggccagccgg acggacttcg gtccgaaacc cgagacgtag accggcgggg
      901 gctcctcggg cagggtatac agccgggcgt tctccaccgt gtaatggttg ccgtggaagt
      961 ccttgacccc gccctcccac agcaggcgca tcaggtgcac ggcctcctcc agcatctcca
     1021 gccgcacgtc ggcggggggc cagcggtcgc ccaggatgtg ctcgttgagg ttctcgccgc
     1081 tgcccacccc gagcacgaag cggccctcca gcatcaccgc ggaggtggcc gcggcctggg
     1141 ctatgatcgc ggggtggatg cggatggtgg gacaggtcac cgcggtggtc accgggagcg
     1201 aggtaacccg ggagagcccc ccgatcaccg accagacgaa ggggctgttg ccctgctcgg
     1261 agttccaggg gtggaagtgg tccgagatcc agagcccctc gaagcccgcc gcctcggcca
     1321 tctcggcctg ctccagcagc tcccgcggcc cccactcctc acaggacaga aagtacccta
     1381 tcttcgtcat cggttcctcc cgcgcagaga gaatgcttcg ccggcatgac ccgccaattg
     1441 ataccccgcc cgctgcggca tctaaccgcc tgcgagctcg atctttatcc cgtcgcgggc
     1501 aaacgaggcc tcaaccccgc gtttctggcc gagtcgtcgg atttcctccg cgacccgctc
     1561 ctcgttgccg gccacgatct cggttccgca gtgggtgaag atcgcccgcc gcaccccctc
     1621 cttcatgcac caggtgagcc gggtcctgat gggggcgtgc ccgagagggc ctccccacgc
     1681 cggtgcacca gcgggcgggt gacgctcgcc ccgtcgccca cgtacagcag gaccccgaag
     1741 agcgcctccc cgcggccgtg gatgtagacc atgtcgggag cgtagaagac ggcggcttct
     1801 cccgtcgaga tcctgtagcc caccgccggg gcgcgggtgg agtgcttcct tcgcggctcc
     1861 acgacgcgcc gctctgcgac ggggcaaccc tccagcgtcc gccacgagac ctctgtggcg
     1921 tagaccgggc agggggcccc ttcctgaggc cccaggcgtg gtccgggtgg gcgtgggtca
     1981 ccacgatggc cgccacgccg agctcgtcga agcgccccag tccaccatga ccctgccgcc
     2041 gcaggagacg acgagcgcgc tgtgcatggt gtgcctgggg gtgtgcgcct cgatctcgcc
     2101 gcgggtcccg gcaagaggag cctcacgctc cctcccgccg cagcaggcgc cgcagctccc
     2161 cgagggaccg ggtgttgacc acgtcctccc tctccagcca gccgcgccgg gcctgcccca
     2221 ccccgaagcg gatgttcgcc agctcgttgg tgccgtgggc gtcggtggag acggctatcc
     2281 tgacgcccat ctccttggcc agcctgcagt gggcgtcgtt caggtccagc cgctccgggt
     2341 tggcgttgag ctccaggatg cagccccgct ctactgccgc ctccatgacc ctctcgacgt
     2401 ccagctcgca gggctctcgc cgcccgatga ggcgtcccgt cgggtgggcc aggatgttga
     2461 cgttggggtt cgcgagagcc cgcagcaccc gccgggtctg ctccctctcg gggagccgga
     2521 gcttgtggtg caccgagcag atcaccacgt ccagctcccg caacaccccg tccggcaggt
     2581 ccagcgaccc gtcctccagg atgtccacct cggcgccttt gaggagggtg atcccctcca
     2641 gctcctcgtt gagccggtcg atctgctcca tctgctcccg cagccgccgc tcgtcgagcc
     2701 cccgggccac ccgcagcctt cgcgagtggt cggttatcgc caggtactcg tagccgcgct
     2761 cttcggcggc ccgggccatc tcctctaggc tgttgcggcc gtcggtggcg gtggtgtggg
     2821 agtgcagatc accccggatg tcctcccggg tgaggagctc cgggagcgca tcctcgcttg
     2881 cggcctctat ctcgccccgg tactcgcgca gctcgggttc gatgtagcgg agaccgagcg
     2941 ccccgtagac ctccgcctcg gtccgtccgg ctacccgttc ttcaccccgg aagagcccgt
     3001 actcgttgag cttgagcttc ttctggaggg ccatgtcgcg cagggccacg tggtggggct
     3061 gcgcgccggt gaagtacagg agcgccgccc cgaagctctc ctccggcacc acccgcaggt
     3121 caacctcgag gccgtctttg agcaccacgg aggagcgggt gccgcccctc gagactaccc
     3181 gctccacgcc gccgaaggct acgaagtgct cgacgactcg ccgcccgtcg tgcgagcagg
     3241 cgaccacgtc gagatccccg accgtctcct tccggcgccg gaagctcccg gccacgacga
     3301 cctcccgcac ggccgcgcag cccctcaggt gctcctccag cgcccgggcg gcgggctcgg
     3361 cggaggccag cctgaatcgc cgcggtgtct ctccccggga gagcgcctcg aggatgttgc
     3421 gctcggtctt ctcgccgaag ccgggcagcc tccgcacccg cccctcccgg gcggccctct
     3481 ccagctccgc ggcggaggtt atcccgagcc tccggtgcag ctcccgcacc cgccgcgggc
     3541 cgagccccgg caccccgagc agggaccgca gccccggcgg cacccgctcc cgcagctcct
     3601 cggtctgccg cagcgttccg gtacgcacta tctcccggat cttgcccgcc agatcctccc
     3661 ctatcccggg gaggcgggtg aggctctcgc ccttcccgac catctcggcc aggctccggg
     3721 ggtggttctc tactgtgcgg gccgcctccc ggtaggctcg cacccggaag gggttctcgc
     3781 cctctatctc cagcaggtcg gcgacctcgt ggaggatcgc ggctatctcc gcgttgtgta
     3841 tcggcaccct acacctccat catcttcttc agccgcccgg cgtcgcgagg ggcgtacccc
     3901 gcctcgtcgt tgtcgaagta gcagtacact tccacccctt ccccggccca tccgcggagc
     3961 agcccggccc agcccgcgag ccggcgctcg ccgtagcagc cccggtaggg gccctccggc
     4021 ccgtggagcc ggacgtaggc gaagccggcg gtgaggacgg gcggggaggt ttgccccgcc
     4081 aggtcgtaga cgcacaatgc cgccccgtgc tcccggagga ggcggtagat cttctggttg
     4141 aaccagctcg cgtcccggaa ctcgaaggcg cagcggcggc cgggggggag cgccctcagc
     4201 aggccctcca gccgcttctg gttcgcacgc cagcggggtg ggagctggaa gaggacgggg
     4261 ccgagcttct ccccgagcgt ctccagccgc ccgaagagcc gctgcagcgg ctcttcgggc
     4321 tccctgagct tcttcatgtg cgtcaggtag cgcgaggcct tggccgcgaa gacgaagccg
     4381 tcgggcgtcc ggtcgcgcca gcgcgccagc gtctcctcct ccggcagccg gtagaaggag
     4441 ttgtttatct cggcggtcgc gaagtgggcc gcgtagtgct ccagaaagcg gctcgcgggc
     4501 agccccggcg ggtagaagga accccgccag tggtcgtagt gccagccgga ggtacctatg
     4561 tggaccctgc cgccgaccgc tctcaacctc ccctcggctg tctcccgcgc gcagggagga
     4621 ttattcctgg gtgggctctt agcgaaacgc tatccctcca ccgggtggac ctccagcccg
     4681 tcctcgttca cctcctccca ctggcgggcc atccggtcta tgacctccgg ggggacgggc
     4741 tcttcggagg tctggttgcg ccggaggcac tcctccttcg gggtcttgag tacgtaggcg
     4801 cacaccggga cccccagctc ccgggccagc cgcagccagg gggcgcggcg gtggcgggtg
     4861 gtgttggtgg cgtcgagcac cacccggtgg cccccgagga gcagggcccg gaccgagagc
     4921 tcggcgttgg cccacaccag gggttcggcc ggcgggtagt ggccccggcc gtggagggcc
     4981 cgccggatct cgtcggggca cacccgcacc cagccgtggc tctgcaggcg gcgggcgtag
     5041 gtggtcttgc cgctcttggg cagcccgcac atgagcgcca gccgggcccc ggtgtcccgt
     5101 tcgctaccca cgggggcatg gtaccccttt tgcgggcgtc ggccggtggg aggcggcggg
     5161 ggctccggta gaattctcta gaacgaggtg cccccgagcc ggaggtgacg tttttcagat
     5221 gtgcggcagg tacacgctcg ccacgcccgt cgggcgggtc gcggagcagt tcggggccga
     5281 gggtccgctg ccggagatcc cgccgagcta caacgtggcg ccgggtcgcg gggtggccgc
     5341 ggtggtgcag gagggcgggc ggcggcgact ggaggtgctg cgctgggggc tcgtgccccc
     5401 gtgggcggag gacccccgcg tgggcgaccg catgatcaac gcccgggcgg agaccgcggc
     5461 gtcgaagccc tccttccgcc gggccttccg ggagcggcgc tgcctgatcc cggcggacgg
     5521 cttctacgag tggcggcggc tcgacggagg caagcagccc tactacgtcc gcaggaggga
     5581 ccgcgcgccc ttcgccttcg ccgggctgtg ggaggtgtgg cgcggggagg agggcgagct
     5641 ccgctcctgc accatcctta ccacgcgggc caaccgcctc ctcagcgaga tccacgaccg
     5701 gatgccggtg atcgttccac gggacctcta cggcctctgg ctcgaggccg aaggggagag
     5761 agaggagctc gatgcggtgc tccgccccta ccccgaagag gagctcgagg cctacccggt
     5821 gagccgcctg gtgaacagcc cggccaacga cgacccccgc tgcatagagc ccgccgcctg
     5881 atgcgcccgg tgcagcccgc gcccgaggtt gcagaggccc tgcaggaggg ccgtcccgtg
     5941 gtggcgctgg agtccaccct gatctcccac ggcctgccgc gcccggacaa cctgcgggtg
     6001 gcccgggctc tggaggagga gatccggcgg gagggggccg tcccggccac cgtcggggtg
     6061 gtggagggcg tggcccgcgt ggggctcggg ccggaggagc tcgagctcct cgcctccggg
     6121 gaggtgccca agctctccgc ccgcgatctg cccgccgcgg cagcgaaggg tgtgagcggg
     6181 gccaccacgg tcgccgccac cgcccacctc gccgcgctct gcgggataaa gctcttcgcc
     6241 accggcgggc tcggcggggt ccaccggggg gcccgcgaga gctgggacgt ctcggcggac
     6301 cttgccgccc tctcgcgcac ccccgtcgcc gtggtgtgct ccggggtgaa gtccatcctg
     6361 gacgtgcccg ccaccctgga gcagctggag accctggggg tcccggtggt gggcttccgc
     6421 agccgcgcct tcgccggctt ctacctctcc gactcgggct gcaccctggc ctggtcggtg
     6481 gaggacgaga gggaggcggc cgccctgatc cgggcgctcc ccggcctcgg gttgggatgc
     6541 ggggtggtga tctccaaccc cctgcccccg gaggagcagc tcgatcccgg cctccacgag
     6601 cgggtgttgc gttcggggct ggaggagctg gcgcggcgcg gcgtctccgg caaggaggtg
     6661 accccgtttc tgctggagca cttcagggag cgtacgggcg gggagagcct gcgggcgaac
     6721 gagcggctgg tcctccgcaa cgggcggctc gccgcccgca tcgcgcgccg cctctgcgaa
     6781 gagcggtgag cgcgccccgc gccgtcgtgg tgggtgacgt gctctacgac atggtcgccc
     6841 gcatcgaggg cgagctcccc atcggcgacg acagcttcgt cccgatccgg gacgcccccg
     6901 gcggttccgc ggcgaacgtc gccgcctggc tggccatcct gggcgtggag acccacctcg
     6961 tcgggagggt gggcgacgac cccgtcggcg agcacctgga ggccggcctg cgggaggccg
     7021 gggtaaggac acacctcttt cgggatgcct ccctgcccac cggaaaggtc ttcgtgctcg
     7081 tggacggctc gggggagcgg accatgatca ccgaccgggg cgcgggcgag gcgctcggcc
     7141 tgcaggatct cccccttgag ctcttcgcct ccgggggcca cctgcacctc accggctacc
     7201 tcttctccgg gggaagccgg cgggcggtcg ccctggaggc cctgcgcctc gcccgccggg
     7261 cctccatgag cgtctcggtc gacccctcct cggtgacgct gctgcgggcc gtgggtccgg
     7321 agcgctttct ccgctggacc gccggggcgg atctcgcctt ccccaacctc gccgagggtg
     7381 ccctgctctc cggccggaag gagccggagg aggtgttcag ggttctgctc gggcactacc
     7441 gggccgtggt gctcaagctc ggccctgagg gggcgctgta tgccgggcgg gacggggcac
     7501 gagagcgcca gaccgcgccc cgcgtcgcgc ggcccgacgc cactggagcc ggggacgccc
     7561 tgtgcgccgg attcctcgcc gcccggctgc gcggacggcc tcccgcggag gccctgcgca
     7621 tgggggtgcg cctcgccagc cggatcgccg ggcacaccgg ggcccgcggc tttcacgccg
     7681 gacgggggcc gtgctaagat cggttctcct ccggcggaag ttggatgtca tgcgctcagc
     7741 ctgtgacagg gaggggaccg cggcggggaa gggcccggaa ccggacgatc tgcgcctgct
     7801 gcagtttctg ggctgggtgg tgcccctggt cttcggcttc gccgcgctcg ccggggtcgc
     7861 cgcggccgtc ttctccgatg cggggcttct ggccgcgggc gtgatcctcc tcgcctacgg
     7921 cgggctgctg ctggtggccc gccgccgggt ggggatcggg gggcggggct ccgcggtgtg
     7981 gacgatctgc gtcgggctgc tgctcgcagc cctgctcatg tctgccgtcc agcccgggtg
     8041 gctggcggtg ctcgcgatca ccccgctcat ctccgtggcg gtggcgctcc cctacgtgcg
     8101 gggcggggat cttctgcgcc tgatcctcct cgcctggctc accgtggtgg tcatggcggt
     8161 tctcagccgg acgctgagac ccctctccga gccgccgggg tggttctccg acgtcttcgc
     8221 cgccagcgcg ctggccgccg ccagcgcggt cgtgctgctg ctcctctggc agttcagcag
     8281 ccggctcaac gagacgctgg cccagacgcg ggcggcggag gagcgctacg ccctggtcga
     8341 gcggggggtg aacgacggtc tctgggactg ggatctgcgc cgggacagga tctactactc
     8401 ctcccgctgg aaggagatgc tgggctaccg ggaggacgaa atcggggcgg gccccgagga
     8461 gtggttcagg cgggtccacc cggaggaccg caagcgcctc ctacaggagg tgggggacca
     8521 cctccggggc cgccgggagc acctgaacgt cgagtaccgc atccgccacc gggacggctc
     8581 gtaccgctgg atgctgaccc gggggctggc ggtccgcgac ggggagggga acccggtgcg
     8641 gatggccggc tcccagacgg acatcacccg ccgcaagcgg gccgaggagg agctcctcta
     8701 cgaggcctct cacgacgccc tcaccggcct gcccaaccgc gccttcttca tggagcgcct
     8761 gggagaggcc ctccggcggg cgcgctcgga ggaggggttc cggctcgcga tcctgttcgt
     8821 ggatctggac cgcttcaaga tgatcaacga ctctttgggt cacacgattg gggacaggct
     8881 cctggtggcc gccgccggga ggttgaggga gtgcctccgg ccgcaggaca cgctggcccg
     8941 gctggggggt gacgagttca cggtgctgtt ggaggacgtc tccggcgagg aggccgccgc
     9001 ggtcgccgac cggctgctgg agcggctgcg gacccctttc tacctggatg gttacgagct
     9061 gttcacggcg gcgagcgtcg gggtcgtgct cggcggtcgc gagtacgcca gcccggagga
     9121 cctcctgcgc gacgcggaca tcgctatgta ccgggcgaag gccgtcggcg gggggaggaa
     9181 ggggatcttc gaggccggga tgcacacccg ggcggtggag ctcttccgcc tggagaacga
     9241 gctgcggcgc gccatcgagc gccgggagtt caccacccac taccagccca tcatctcgct
     9301 gaagaccggc ctgatctcgg gtttcgaggc gctggtccgc tggcgccacc cggagcgtgg
     9361 gctggtcctc ccggacgagt tcatcccggt cgtcgaggag acgggcctga tcctcttgct
     9421 ggagctctcg gtgatgcgcg aggcctgtgc ccggctggca gcctggcaaa aacggttccc
     9481 ggaccaccgg ccgctcaccg tgagcgtgaa cctctcccgc aaccagctcg tccggtcgga
     9541 gctcccggag cagatagagc gtaccctgct ggagaccggc ctggacgccc gctccctgcg
     9601 gctggaggtg acggagggcg ccctcatgga gaacgtggac tcggcggtcg ccaccctctc
     9661 ccgcctgcgc gacatgaaca tccgggtgca catagacgac ttcgggatgg ggtactcctc
     9721 actgagcgtg ctccaccagc tgcccataga cgccctgaag gtggaccgct ctttcgtggg
     9781 ccggatggac ggcgtggggg gcgacgcgga gatcgtacag acgatcgtaa ccctggccca
     9841 caacctgggc ctggacgtga tcgccgaggg ggtggagcgg gaggagcacc tgagacagct
     9901 cagaaaactg ggctgcgact acgcccaggg cttcctgttc tccgagcccc tggacgccga
     9961 gaacgcccaa cgcctgatct cctcttaccg gcggtggtag tcagggggag gcggccccga
    10021 cccggtagcg cgccgactcg taggtccact cgaggttgcc cctcatccgg gtcttgagca
    10081 cccagacgta gcgccgcagg ttgtcgtcga cggccggccc gaaggagggc agctccttct
    10141 ccagccggac gaacctgcgt acctccgctt cgtacatccg gacggcctcg gccaccgcct
    10201 ctccgagcgg cagccgccgg ctctcgcaga ggacgaggac caggttgtgc acgtcgccgc
    10261 gcgagcgctc cttggccagc gagatgatgt cgttcgccca gcagaccacg ttgttggagg
    10321 cctcggtcag ggagctcacc acccgctccc ggtggacctc cggcggcagg tagatgccgg
    10381 aggtgacctc tatgaagtcc gtgtcgacgt gcatcccacc ggttatgggg cgcatccgga
    10441 cgtatgtcgc gagatccggc gtgaccccgc gggcccggtt ggtggcctcc cagagtgtgg
    10501 actcgaagtg ctcctccacg gagcggagaa aacgccgcag ccagagcgga ccgggaactt
    10561 tgggcagcaa gcgctcccgg aggtcccgta gcgcccgccc gaagggcccg tgttcttcgc
    10621 cggagatcct cccggagagg atgtccagaa aggccgcatc cagcgcggcg agccgctccg
    10681 gatgccggaa gtacgcggga tcgtccgcca gatcgtcccg caggaacatc caggcgcacc
    10741 agtcggagat gagcctgagc tcctcgcgcc ccgcacaggg atggaaacga ccggcgagcc
    10801 gcccgatctg ggtgtcgcgg accatccggc ggctctcccc ggaggccagc agcccgaaac
    10861 cctccgccca ctccactgtc tcccggtgaa ccccgtcggc gtgcgggttc atcgccgcag
    10921 ggaacggaca gcgcaaccgg ggaacccgca ccattccgtt cttagacgat cccatccctc
    10981 agccaccctc cgccagagac ccgcccgagt atacccccgc cgtacttcag ggtgaagtat
    11041 gaccctgaac ctcagggaga catgtgccat aaagtgcggg ttcaggtcat ctccagccca
    11101 gggtggcgag gtcgaggcgc tccttctcct ccggggagag gctccagccg agggctccgg
    11161 cgttctggcg ggcctgtgag gcgtctttgg cgccggggat ggggagggtg ccctgggcga
    11221 ggagccagtt gagggcgacc tgggcggggc tcttgccgtg gcgttctccg atctcgcgca
    11281 ggatcccgac caccggctgc acccggcgca ggttgcgctc gccgaaggcc cgtcccagtc
    11341 tgcggaccag tcctggaggg cgggagccgg ggccgtactt gccggtgagc aggccctgcg
    11401 cgagcgggct gtaggcgatg agggtgacgt tcagctcccg gcaggcctcg agcgttccgt
    11461 cggtctcggg ggttcggtgc agcaggctgt actccacctg gtttgatgcc aggggcactc
    11521 cgcgggcgtc caggcgctcg aaggcccggc gcatcgcctc cgctccgtag ttgctcaccc
    11581 ccacgtggcg ggccttgccc tccttcaccg cttccgccag cgcgtccagc agcctgtcgg
    11641 ggggcgggat cggggagtac cagtggatct ggtagaggtc cacgctctcc accccgagtc
    11701 gccgcaggct gccgtccagg gcgctcagca gcgagcgggg gctcagccgg taggggtagg
    11761 gggcgaactt cgtcgccagc accggtcggg ccgggaggcc gccctcccgc aggacgctcc
    11821 cgatgatccg ctcggactcg ccgttgccgt agatctcggc ggtgtccacc agccggacgc
    11881 cggcggcgag gctctcgtgg agggccgcgg tgacctccgc caggccgtag cctgagccgt
    11941 agccccagag cctccgggtg ccccaggccc acgcacccac ccccaggggc tctatgccca
    12001 gccggattgc cagcggcgcc cgttcgtagc cgttcatcac ggttggtttc ctttctctgt
    12061 cggtcgcttc ccgttgcttc cgggcgcttt gatcctcccg gcggagacga agtccgccac
    12121 ctcgcggttg aagtcctcgg cccgctcgtc gtggggcagc agcgctgcgt cccggaagat
    12181 gcggggggca gtccgcgggt tgtaccgcag gaaggcatcg agctcggccg ggggcggggt
    12241 tcgggcctcc cggccccagc acaccatgac ccgctggcgg agctgcgtcc agcaggggag
    12301 cgccggttgg ttgagcttgc ccgccacgaa ggccgccggg aggaatttgg cgttcggtcc
    12361 atggctcacc cggtagtggt cctcgacgat ctcctccgtc acccgggagg gatcgtggta
    12421 ggccatccgc tccagataga gccggatgcc ccggtgggag accagggcgt ggtagaggag
    12481 gtcgccgagc agcggcgaga cgagcagccg gtagacggcc tccccgagcc gtcccgaggg
    12541 gcggtccagg gttccgaggc cggtcgggca gatcaggacc aggctcctga acaggcgggg
    12601 gctgcgcacc gcggccggca gcgccagtgc cgccgagagg gagctggcca ccaggtgggt
    12661 cgggcgctgg atctcttccc ggacgaagtc ttctatctgg gaggtcacgt cctccggggc
    12721 gtagcgccgg cgcggtttct cggaggcccc gcagcccagc agatccggcg cgtagaccgt
    12781 gaagtggcgc gagagcggcc cgaagttcct ccggaactcc agggaggagg ccccggcgta
    12841 gatcccgtgc accaggagca gcggcgggcc ctccccggcc accgagtacg cgatctcccc
    12901 gcccttccag cggtagcgcc gccgctcgcc cccgagggcc gttcgcggcg ggccgccgct
    12961 ccgctccaag tgccggttca gggcatggag cgctcccagc gttcccgcgg tggtcagcgc
    13021 cgccctcatc agcctcattc tctccccaag cctccgatcc gtcgtgccgg tccgctcttg
    13081 cccgcagaga tcttatatcc tacgctcgca gccgcagggt gccggccctc tcgcttttca
    13141 cctcgacctc gaccggtccc tcgccccgca ccacccacac cacccgtcgg gcgtacgccg
    13201 aggggaggcc gtcgaagaag gccggggact tccaggagct gccctccagc gccgagcgtc
    13261 cggccagatg ccccagctcc accacccgct cccccgagac cagctcggct ccctccggca
    13321 gctcgaggcg cgcctcgggt ggtttggcga gctttcgctc ttcggccacc cgggtcacgc
    13381 tcgtggggag gtagccggtg ttctccacga tcagctccag ccgccgcagc ccgcccggga
    13441 gcgtcttggc cgagagccgg ccgtcgagca gcggtgccgt gcgggcgtgc gccagggcga
    13501 accggaaggc ccgctcgcac tcggcctcga gcaggtgcgg cggcgggttc tggaaggtga
    13561 acttcgtccg ccagcccccg atctccaccc tccccagctg cgggtgatcg aagggcctcc
    13621 acctctcgaa gccctctcca tccagctccc ggtcgttcca ggccagtatc cgcagcagcg
    13681 cctcctccgg agggtcgcgg aagaagccga tgaagtcctc gaccttcacc ccggcggccc
    13741 gggccaccga ccagagctcg atggtgaagg cgaagacccc gtaggcgtcg taggcccagt
    13801 cgtcgaaggc tccgctgatg gtctttctcg gatcgtagcg aaagccgtgg tagacggaga
    13861 ggttggggta gccggtgagc tcggtacccc ggtcaccgag cgccctgtag acggcgaggt
    13921 cgtggtcggg catctcgagg tcgtcccggt cggagtaggg ccggaggatc gctccacaga
    13981 aggtgtggta ggtgtggatg ccgaagacgt tcctgcgccg gagcagggcc tccacgtggg
    14041 cgcgcgactc cggttcggag agggggtagg ggccggcccc gggctgctcg tgctcgccct
    14101 gccagcggta ggggtactgg cggttcatgt ccaggccgtg caggggccgg gcgatcctgc
    14161 gctcgaaccc gtcgtagtcc ctgaaggtcc cctcccggta gagccggtag taggtgccgc
    14221 ccgtctcgtc gggtctgcgc cggaccatca gccggggatc cgtctccgag accttccact
    14281 ccccgtgctc gtcttccacc cgcatgtgga ggatctcacc gtcaccgtcg acgtcctccg
    14341 ggtgcagccc cggttcctcc tcgggctccg gccacgggcg gagcgtggcc ctcagggtgt
    14401 ggggggtctt caggtagcgc tcggccccgt cgggggagag cctggggagg acgtagaacg
    14461 cctgcgcgtc caagagccgc cgcatccccg gatcggagga gtagcccgtg agcaggcggt
    14521 ggatcaggta gagcgccgcc atcgagccgg tgacctcccc ggcatgggtg ttcccgtcca
    14581 cccagaaggc gggctttagg tcggccggac cggtcgcggt gttggtgatc tccgcgagcc
    14641 agatctcacg cccctcgtag ctcctgccca cctcctccac ccggcacagc tctgggtgct
    14701 cccgggccag accgtgcagc gccgccgtga gctccgcgtg gtccaggtac ctgtcgaagc
    14761 gaatctttct ctacctcctt ccgtagcggg gcctcctcaa gaggggcatt ttaggggaag
    14821 cgccggccgt gggccgcacc acaaaatatt gggcgaaaag tggtaaggtt cccaggtgtt
    14881 ggggggcgga gcggtacctc ctctggttgt gtatccgggc tgtcgggggg gatatataat
    14941 tgcctgctag aagggaggcg gccggaggcg ggagagagct ggagacctcg gctaaaacgg
    15001 tgttcgggga ccgctacgtg gtccgcgaga agctcggctc cggcgggatg gccgtggtct
    15061 accgggccga ggacaccctc ctcggccgcg acgtcgcgat aaagaccctc caccgccgct
    15121 acgccgaggt accggccttt cgccgccgtt tccggcagga ggcccgggcg atggcctccc
    15181 tggaccacca gaacatcgtc aaggtctacg acatctctcc cgacggcgat gcgccgttca
    15241 tcgtggagga gtacgtgggg gggcgcgacc tcgggagtct gctggcccgc cagcgcggcg
    15301 ggcgtctgga ggagtccttc gccgtccggg tcgcggagca gctgctcaaa gcgctcgcct
    15361 acgcgcactg gcggggtgtg atccaccgcg acataaagcc ctccaacatc ctcataaccc
    15421 ccggcgggat cgtgaaggtc gcggacttcg gcatcgcccg gctggtggag gacgagggcg
    15481 aggggggcgg tgagatcatc ggcagcgccc gctacatgtc gccggagcag ctgcgggggc
    15541 tggaggcgac ccctcggagc gacctctact cggtcggcgt cctgctctac cactgcctca
    15601 ccggccgccc gccgttcacg ggtgacgtaa agagcctcgc ccggcagcac ctcggggagg
    15661 tgccgcgacc gccgcgggag ctgaaccggg gcctctcccc ccagatggag gcggtgatcc
    15721 tccgggcgat ggccaaggac cccgaggacc gctacccctc ggccacggcg atgctcgacg
    15781 agatccagga gggggtccgc cacagggccc gctccggcac ccgggagatg ccccggaggc
    15841 ggacgaggcg cgggaggctc gccctggtct ccacgctcgc cgttcttttg ctcggcgggg
    15901 ggacggcggt aggggcctct gggctggccg gatacgtgga cctctcaccg cgctccagcg
    15961 tgcagcagcc ggtcgtgggg gctgcggagc cgctgcgctc cgccccaccc ggtatccccg
    16021 agacctcccg ggaggaggcc gcccggaacg cgccgctcgt cccggtcccc gacgtccgcc
    16081 cgtacttcga ctactcggcg cgcgagatac tcgtcaaccg tggcttcaag gtgcgcatcg
    16141 tctacgccta ccgggagggc tacgccaacc ggggggtcgc ctggggcacc gacccgcccg
    16201 cagggacgct cgttccggcg gggtccaccg tgacggtcta ctcgacgccg aaggatctct
    16261 accagcccca gatacgcacc accggggcct cgccgtaggg ctcagggacc gacccagcgg
    16321 ccgaccaccg ggtagcggta gtcctctccc cggctcaccc ggtaggcggc gtagcagccg
    16381 tgggccatcg gcagcaccca ggcagccacc gcgagcggca ggacgagtat caggccgagg
    16441 ccgagcgtga acaggacgaa gagcaccccg gagatcgccc cgacgaccca gatggccagc
    16501 cacaccgcct ggtagaggag ggcctgcagg gcgtgaaagc ccacgcgggg agaacggtcg
    16561 cggtagacga gccagatgac gagcgcgccg accggcatga gccccaccag accggcgagc
    16621 gcgctcaggt gcgccattgc cgaccaggtt cgctcgtcct cggggctcat gtcccctcct
    16681 ggaggggagg gtcgcagtac gtctcgctgc ctgccgtagt tcgggtctcg ttgcatggcg
    16741 tatcgtgcct cctctcgcgt tcatcctcgg gtccgaagga gaaaggcccg gctccgcacg
    16801 ctggccaggc ggtacagcag gaagagggca accggaagcc cgcactcccc ctcgaagcgt
    16861 gcatcgtacc gcatcccgac gaggtctccc tctacccggg cgcacccccc gggcccgcgc
    16921 gccgtggcgg cgtttcgcag gagccggagg ttcgactccc agatctcgcc gccgggttcc
    16981 atcatccaga agcccttcgg tgggccctcg gccgagagcg cctccacgtc ctcccagagc
    17041 atcgcgtagc gctccccggg cttccgctcg acggtcgcgc tggttttcgc ggcggtgagc
    17101 ctcgccccgc cggggccctc catccgcagg tgcccgaact cccggccgtc ggtccggaac
    17161 agcgagaacc ccgcgggcgg gaggccgcgg gccgcaaaac ggcctcccag ctctcgggag
    17221 aggccgctcc agggtttctc cagaggagtc atggtgtaag ctcatacgct gaccgccccg
    17281 gtggagtttc gccggggaag cggctacagt ttcgatcgtc gagacggaag ggatgccaga
    17341 tggaactcaa gaacaaagag gagcttagga acgagatcct ccagtcctgg ctcagggatg
    17401 cctgggtcta ccccgtagag gggccggaca gaaagatata cctgcgcctc acgccgggtg
    17461 ggaggctcaa gatgcgcaag aagatcgggg agatggagcg ctccctcggc gtcagcggcc
    17521 cggagctggt ccggcaggac gaggccggga cccttcccct cgaccgggac aggctcgagc
    17581 tggccatgat ggtccgcgcc tacacctccg agcggcgctt catcgagagc tcgggaggat
    17641 ctttggggag cccggccgtg accctggagg aaggggacga gggttcctcc taggccgcgg
    17701 tcctgcggtt caggcggcgc tccagaacgt tggtcaggta gatcaggggc aggcagatcg
    17761 ccaggtagat gagcgccgcg gcgatcagcg gcgtcccgtt gaaggtcgcc gactgcagca
    17821 cccgggccgc ccgcagtagc tccgccagac cgatcacgct caccagcgag gtgtccttta
    17881 tgagcgtgac gaactcgttg gtcagcggcg ggatgacccg ccgaaacgcc tgcggcacga
    17941 tgatgtagcg catcgtctgg gcgtaggtga gcccggaggc acgtccggct tccatctggc
    18001 ccttgtctat ggactgtatc ccggcccgga agatctccgc cacgtaggcg gagctgttga
    18061 gcgcgagggc ggtgagcccg gcgaagaaga ggctggtgaa ccggacgccc accgccgcgg
    18121 tggtgaaata gattatcgtg atctggacca gcagcggggt gccccggaag acgtcgatgt
    18181 agatttgcgc cgggaggctc agcagcctgg agcgcgagat cttcagcagc gccaggaaca
    18241 gccccagcac tatcccgacg acctccgcca gcgccgccag cgagagggtc accgcgaggc
    18301 ccctgagcag gggaccggag ttctcgagga ccgtcccgaa gtccaggtag tagccgacca
    18361 gcctctccag cgagaggtct tgcgggttga tctctaccgg cggccaccag tcgggcatgc
    18421 gccctcctca ggggcccgct aggggatctc ctcgggctta cgcccgatcc acttctcgta
    18481 gatctcggcg taggtgccgt cgctcttcat ctcccgaagt gcccggttga ccgggccgac
    18541 caggttgctg cccttgggga aggcgatccc gtactgctcc ccggtgggga tgacctgcac
    18601 cacctcgagc ctgccgtcgc tggtgttggc cttgtcctgg gagacgggca ggtcgtttat
    18661 gaccgcgtcc acctggccgt tctccagcgc ggtgaaggcg tcctctatgg tgtcgaaggt
    18721 gcgcacctcg gcgatcctgc cctgctgctg gaactggttg gccttgttcg ccccggtggt
    18781 gcctatctgc acgcccaccg tggcctgccc gaggtcgtcc accgagcgga tctcggagtc
    18841 gctgcgcacc aagagcgact ggtcggcgtt gaagtagggc tcggagaagt ccacctgctg
    18901 gcggcgctcc tcggttatgg tgatggccga gatcgccgcg tcgtagaggt tggagccgag
    18961 gccggggatg atcccgtcga aggtgacgtt ctggaactcg ggggtgaacc cggccctgcg
    19021 cccgatctcg cgcatcagat cgatgtcgaa gccgaccggc tcgccgttcc tgtagaactc
    19081 gaaggggcgg taggctatgt cggaggccac ggtgacggta cgcccggtct ccatcccggt
    19141 cgtcccctcg ccgccaccgc cggcggtctg ttcgccccct ccgccaccgc ctccgcaggc
    19201 cgcaacgagg aacagagcgg caaccaccag cgccagcgtt acgaagtttc gctccacctt
    19261 tcttcgtgac atccctcttc ctttctctat ctccgccggg gacgacaacc tggcaggaac
    19321 atacgatact ttagtagccg caaatactag ttgttcctgc accctccggt caaggcggcg
    19381 tccctcgcgc cgaagagacc cctacatgtg caggatcctg tccaggaaac gccgggcgcg
    19441 ctcgttctcc gggttctcga agaagtgctc cggggtgccc tcctccagga tgcgcccttc
    19501 gtccatgaac accaccctgt cggccacgcg ccgggcgaag cccatctcgt gggtgaccac
    19561 caccatcgtc atcccgccgc gggccaggtc caccatcacc tcgagcacct cgttgatcat
    19621 ctccggatcc agggcgctcg tgggctcgtc gaagagcatg atcttgggct ccatcgccag
    19681 cgcccgcgcg atggccaccc gctgctgctg gcccccggag aggttctccg ggtacttgtt
    19741 ggcctgctcg gggatcccca cccgctccag tagccgcatg caccgctcct cggcctcctt
    19801 gcgcgagagc ccgcgaacct tcatcggggc cagcatgatg ttctgggcga ccgtcatgtg
    19861 cgggtagagg ttgaactgct ggaagacgaa tcctatctcc gtgcgcagcc ggttcagatc
    19921 cgccttttcg tcgtgcaccc ggatgccgtc cactacgagc tcgccagagg agatgtcctc
    19981 cagcgcgttg atgcagcgca gcagggtgct cttccccgag ccggaggggc ctatgatgac
    20041 cacgacctcg ccctcctcca cggagaagtc tatgtccttg aggacctcga aatccccgaa
    20101 ggacttgctg acgttgcgga actctatgat gctcatcgtg tgctctctcc ggcttgcggt
    20161 cccctccggg gccggtccgt gcgcggtgta gaatagcaca accggtagat agccacgatg
    20221 atctcaagga ggggtctctt tggaaactct ctttgacgcg gtcgaggggg gcgagaaccg
    20281 ggaggagcgc ctggccgagc tggcgcgcca ggtctccgtg tgcaccagat gcgacctctc
    20341 ccgcagccgg acgaacacgg tcttcggcac gggcgacccc tactcgccgc tgatgctcgt
    20401 cggcgagggg ccgggggaga acgaggacgc cacggggctt cccttcgtgg gccgggccgg
    20461 caagcttctg gacaacatcc tggcggcggt gaacctgagc cgggagcagg tctacatcac
    20521 caacatcgtg aagtgccggg ccgcggtgga ggagaacggc cgcctccgca accgccagcc
    20581 ccggacggcc gagataaacg cctgcaaccc ctacctgcag gcccagatag aggcgataaa
    20641 gcccgagatc atcctctgcc tcggcggccc ggcggcgaag acgatcatcg acagggactt
    20701 caggatcacc cgcgaccgcg gcaagtggta cgacgtgggc ggcatccggg cgatggccac
    20761 cttccacccg gcctacatcc tgcgccagag cggggaggag ctcgtccgca cgaagcggct
    20821 ggtctggaag gacatccaga acgtctacgc cgagtaccag cgggccatgg agcatcgtgg
    20881 ggtctagtct cccgcgtcta ccactcatcg ccctcgcgct cctcgtcgcc gtctcctgca
    20941 ccggggcccc tgctcccgag cggcgggatg ccggt
//
