LOCUS       NZ_AP019791            20897 bp    DNA     circular CON 25-APR-2024
DEFINITION  Rubrobacter xylanophilus strain AA3-22 chromosome, complete genome.
ACCESSION   NZ_AP019791
VERSION     NZ_AP019791.1
KEYWORDS    RefSeq.
SOURCE      Rubrobacter xylanophilus
  ORGANISM  Rubrobacter xylanophilus
            Bacteria; Actinomycetota; Rubrobacteria; Rubrobacterales;
            Rubrobacteraceae; Rubrobacter.
REFERENCE   1
  AUTHORS   Tomariguchi,N. and Miyazaki,K.
  TITLE     Complete Genome Sequence of Rubrobacter xylanophilus Strain AA3-22,
            Isolated from Arima Onsen in Japan
  JOURNAL   Microbiol Resour Announc 8 (34), e00818-19 (2019)
   PUBMED   31439702
  REMARK    DOI:10.1128/MRA.00818-19 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3022875)
  AUTHORS   Miyazaki,K. and Tomariguchi,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2019) Contact:Kentaro Miyazaki National Institute
            of Advanced Industrial Science and Technology; 1-1-1 Higashi,
            Tsukuba 305-8566, Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.4
            Genome Coverage                   :: 758x
            Sequencing Technology             :: NovaSeq6000; GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007164525.1-RS_2024_04_25
            Annotation Date                   :: 04/25/2024 02:58:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,085
            CDSs (total)                      :: 3,032
            Genes (coding)                    :: 3,015
            CDSs (with protein)               :: 3,015
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 17
            CDSs (without protein)            :: 17
            Pseudo Genes (ambiguous residues) :: 0 of 17
            Pseudo Genes (frameshifted)       :: 5 of 17
            Pseudo Genes (incomplete)         :: 9 of 17
            Pseudo Genes (internal stop)      :: 4 of 17
            Pseudo Genes (multiple problems)  :: 1 of 17
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:10:24
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 727941
            Orig. end                         :: 748838
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP019791.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated at DFAST https://dfast.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20897
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20897
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20897
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10897](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10897)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(95..1102)
                     /locus_tag="RxyAA322_RS03815"
                     /old_locus_tag="RxyAA322_07580"
     CDS             complement(95..1102)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024384.4"
                     /locus_tag="RxyAA322_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07580"
                     /product="DUF3866 family protein"
                     /protein_id="WP_143526994.1"
                     /transl_table=11
                     /translation="MLRRAVALGEPDADGIFELELLEGPLAGRRFAAVCYPELGRMPRG
                     GEEILANTLGLEMGLGTGGLAVAVPPGGAGEVPENRDHFVKLPYTPLQHPAPPPEELAG
                     SLRGVPVAVLPLHSHLAPACCAAAALRPGWRVAFVWQEGGALPVGLSVLVRKLREQGLL
                     SVVVSAGNCFGGDVEAPNVYAALLAAAAGADLVLAGIGPGVVGTGSPYGHGGMAAAAAL
                     NAACALGGEPVLAPRISLVDPRPRHFGLSHHTRSVLEAALAPCRVALPRGAPEAELRGL
                     PERHRYVPVPFGAAGLEERFGLSFESMGRGYERDPVFFDAAAAAVALALGEVDG"
     misc_feature    complement(194..196)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1105..1635)
                     /locus_tag="RxyAA322_RS03820"
                     /old_locus_tag="RxyAA322_07590"
     CDS             complement(1105..1635)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_07590"
                     /product="hypothetical protein"
                     /protein_id="WP_143526995.1"
                     /transl_table=11
                     /translation="MAPRTGVALLRSEPAGTLPLRAAGVASFVAELSWRAGEAPRGPLL
                     PAVPGLPEGVCLRFEEAGRGEGVRLLRGEVRALERRTLGEGLETVLRAVMEAAALSGAL
                     AEVEVVRGEPPREADARTLRRLSRDLLAAGFCAREVPYCWSAVPAGAASWVGTGERGDL
                     AAFLRRHPRWEVL"
     gene            complement(1641..3281)
                     /locus_tag="RxyAA322_RS03825"
                     /old_locus_tag="RxyAA322_07600"
     CDS             complement(1641..3281)
                     /EC_number="6.3.4.2"
                     /GO_function="GO:0003883 - CTP synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006221 - pyrimidine nucleotide
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011564427.1"
                     /locus_tag="RxyAA322_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07600"
                     /product="CTP synthase"
                     /protein_id="WP_143526996.1"
                     /transl_table=11
                     /translation="MSGTKYIFVTGGVVSSIGKGTSAAALGMLLKSRGYRVVLQKFDPY
                     INVDPGTMNPYQHGEVFVTEDGAETDLDLGHYERFLDENLGRLSNVTTGSVYWEVISRE
                     RRGDYLGATVQVIPHITNEIKARIGRLGREKDVVITEIGGTVGDIESQPFLEAIRQFRN
                     DVGRKNVLYVHVSYVPYIEAAGELKTKPTQHSTQRLREMGISPDILICRADRPIGEDIR
                     RKIALFGDVEVESVIPAEDAPTLYDIPLSLHGSGLDALVLEKLGLPSPPARLEQWRSLV
                     RRMHGATREVRVAVIGKYVRLQDAYLSVVEALRHAGGAHEVRVELDWVDSEQISGPESA
                     RERLRGADGVLVLHGFGQRGIEGKIEAARYARESGTPYLGLCLGLQIAVIEFARNVAGL
                     EMANSTEFDEETPHPVIDIMPDQVGVEMGGTMRLGSYPCRLRPGTLAARVYGAEVVHER
                     HRHRYEVNNAYREVLEEAGMVFSGTSPDGRLVEIAELRDHPFFIGSQFHPEFKSRPLRP
                     HPLFYGFVGACLGAADRVAAPAGGEEEVR"
     misc_feature    3275..3291
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.41"
                     /tool="antismash"
     gene            complement(3283..4062)
                     /locus_tag="RxyAA322_RS03830"
                     /old_locus_tag="RxyAA322_07610"
     CDS             complement(3283..4062)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_07610"
                     /product="hypothetical protein"
                     /protein_id="WP_143526997.1"
                     /transl_table=11
                     /translation="MVATALFAAGLLLTPLALATLLPLLPRRPNYATHPVPTAAGLAFL
                     PIILTALSISLLSGLPLWAPAYLLLAGLVGFADDAMGGKEARGFGGHLRALGRGRVTGG
                     QVKVVGMGGGALVVGVVLYGASLSALAAAFLLAGFANLANLLDVRPGRALKFLGLFVPV
                     LAIGAGEVLAGVAGVLGGAVSLFYFDLRGRIMLGDTGAAVWGATVGCLVVAWGPGWVWW
                     AAGTAVLGLTLVAEFHSISGIIREVGILRRFDQWGRT"
     misc_feature    complement(3313..3315)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3928..3930)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4056..4739)
                     /locus_tag="RxyAA322_RS03835"
                     /old_locus_tag="RxyAA322_07620"
     CDS             complement(4056..4739)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="RxyAA322_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07620"
                     /product="glycosyltransferase"
                     /protein_id="WP_143526998.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.4e-08,
                     bitscore: 32.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRPVAVIAARNEQDLLPQTLRALSSIPLALILVVDDGSTDATAA
                     TARTLGAQVLPAAPPDSPGDKGRALRLGILHARKISPEAPLLLADADLGASARHLSSLL
                     AALGPDTPAAVAAFPPATRGGFGLVKRLARYEISRRTGHHPAEPLSGQRALLPAALDSL
                     PGLAPGFGAETGMTLDLLVAGIVPAELPLPLHHRPTGKTPAGFLHRARQGRDVLRALRG
                     ERLPW"
     gene            complement(4747..5547)
                     /locus_tag="RxyAA322_RS03840"
                     /old_locus_tag="RxyAA322_07630"
     CDS             complement(4747..5547)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055070 - copper ion homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022824.4"
                     /locus_tag="RxyAA322_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07630"
                     /product="copper transporter"
                     /protein_id="WP_143526999.1"
                     /transl_table=11
                     /translation="MPDLRYHVISLVAVFLALAVGILLGVAMADRGVISARLQAEITDV
                     SNRLNRQQTQMERLRERTAEDEQLMQGMAEHLISGRLLGLRVALVSGPYADPEVVQDVQ
                     SDLLSAGAELSGPVTLEAPADRSEVSAPGGETTPLAETYLATAREVLRSPEADGIPPDA
                     IVFVGGGGIPPDAPPGTPEALNEAQARMLELFASSGVRVVAAEASGPARSEVELFQSAG
                     VPSVDNADDPAGRAAIVQLILSEDDGSYGTKETASDFFPPPPED"
     gene            complement(5551..6723)
                     /gene="steA"
                     /locus_tag="RxyAA322_RS03845"
                     /old_locus_tag="RxyAA322_07640"
     CDS             complement(5551..6723)
                     /codon_start=1
                     /gene="steA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011564431.1"
                     /locus_tag="RxyAA322_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07640"
                     /product="putative cytokinetic ring protein SteA"
                     /protein_id="WP_143527000.1"
                     /transl_table=11
                     /translation="MKGFHHWGAGEPLGGVRISGLAVPGRKTKRILARLGPGTIPIIDH
                     ENLDRLTAEALVESGVPAVVNAAPSATGSYPSQGAFILARAGVYILDGVGRKVFERVEE
                     GDEVELRGDALYRGGHLVAAGEHLDLETAERRLRESRAAVGAALERFARNTVAFMREEQ
                     DLLFSSLPVPEEVAREIRGRHVLVVVRGYDYRQDLLALRPYLRDLKPYIVAVDGGADAL
                     LEAGWRPDLVFGDMDSVSERGLLASRRILVHAYPDGRCPGAERVRNLGVGRFDTLPAPG
                     LSEDVAILLADQCGAELIVAVGTHVGLVEFLDKGRQGASSTFLTRLKVGPRLVDAKGVS
                     KLYPARVSAAQLAALAAAGLFAASAVVYSSDRVADIFSLLAVKLRLLLGI"
     gene            complement(6720..8423)
                     /gene="recN"
                     /locus_tag="RxyAA322_RS03850"
                     /old_locus_tag="RxyAA322_07650"
     CDS             complement(6720..8423)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: protein motif:HMM:TIGR00634.1"
                     /locus_tag="RxyAA322_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07650"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_172620662.1"
                     /transl_table=11
                     /translation="MASGAEDLSVVLSEISVRNVALIESATLRLSPGLNAVTGETGAGK
                     TLLATALQLLLGGRARAEVVRAGEERAEMEGLFELPEGVLREILPAALGDLAEEVDPRD
                     GLLLRRTITADGRSRCYVNGVSVGVRVLAALGERLVSYHGQREQARLADPAEQLALLDA
                     FVGPEGLEALRERAELWRSVEEARRRLEEIRASGEARLRELDFLRYQIGEIEASGYSRE
                     EMERLLAERERLRNVTGLLEAAAAAAAALAPEEGGGAVEAVSAAASELERASRLDGDLG
                     PLAERLAGASAELGDVLYELRAYLDELEANPERLEEVENRLAELRELERKYGEDVPGYL
                     RRARERLSGLENADEETGRLEEWIFREERRLAELGEEISAARREAARHLAERVQENLKG
                     LRLDRTLFRAELVPCEPGPSGNERVEFVIRPNPGEPELPVRRYASGGELSRIMLALRLA
                     QREPDPSVTYIFDEVDAGIGGETATAVGSRLRELGGRCQVITITHLPQIASEASSHVVV
                     SKEEVSGRTVTRIRRVEGEERRRELARMLSGRVDRVSLAHASNLLVGGGG"
     gene            complement(8393..9208)
                     /locus_tag="RxyAA322_RS03855"
                     /old_locus_tag="RxyAA322_07660"
     CDS             complement(8393..9208)
                     /GO_function="GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006741 - NADP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039482.3"
                     /locus_tag="RxyAA322_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07660"
                     /product="NAD(+)/NADH kinase"
                     /protein_id="WP_143527002.1"
                     /transl_table=11
                     /translation="MTSCRRLEPGSVRRVAIVASRKVDAGYLKRLEGTLGRGGVEIVET
                     RPEDDPDGRDQVDLVFVLGGDGTMLRASRIYPGKVLLGVNFGRVGFMSGMLPEHMEEGV
                     GKLLRDGIEVQEYRKLDVRVGEEAWRTAANDAVLLKKRPHQIASVDVSVGGEELFAFRC
                     DGFIAATPLGSTAYALSAGGPIVSGDARCYVLVPIAPHALVSRPLVLGEEQVTELRLVE
                     RDALLSLDGEEPRELHAGDTVRVRLSAESVKIGRTDDWTWWRAVRRTFL"
     misc_feature    complement(9125..9127)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9195..9992)
                     /locus_tag="RxyAA322_RS03860"
                     /old_locus_tag="RxyAA322_07670"
     CDS             complement(9195..9992)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00478.1"
                     /locus_tag="RxyAA322_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07670"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_143527003.1"
                     /transl_table=11
                     /translation="MSGGRRLDAILVERGLAETRSRAQAMILAGRVRVGDRVVTKAGFR
                     PAPGEEVSLAAPERPYVSRAGEKLEAALERFGVEVEGRLCLDAGASTGGFTDVLLRRGA
                     RRVVAVDVGYGQLDWRLRRDPRVEVMERTNVRHLGAGDLPFAPELVVADLSFISVVLAL
                     SRIFETAGSVREAVVLVKPQFEVGPEKVSRGGVVRDPGAREEAVLRAVEGFGRFGFGAV
                     GVMESPVFGRRSGNREYLLHLLRGEEGRVGPREVREAVGGDLL"
     gene            complement(10001..10897)
                     /locus_tag="RxyAA322_RS03865"
                     /old_locus_tag="RxyAA322_07680"
     CDS             complement(10001..10897)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011564435.1"
                     /locus_tag="RxyAA322_RS03865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07680"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_143527004.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-59, bitscore:
                     199.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLASAGRWERHRRIFEEYLEGLVFTREPRLERLQEAMRYSLLA
                     GGKRVRPLLCMESARLFGEDPERVLPSAAAIELIHTYSLIHDDLPAMDDDDFRRGRPTS
                     HRKFGEAMAILAGDAFFGEALALITLRQEGSCEQRLAVVQELAGSTGVNGMVGGQVLDM
                     AQTGASGEVDPQTLFMIHRYKTGALIKSSARVGAILAGAGEEEQRAISGYALELGLCFQ
                     IVDDVLNATGSTERLGKRAGSDAERGKATFVSVFGLDGARREADAACGRALEALGGLPG
                     DTSALRDLALFVRHRGS"
     gene            complement(10881..11300)
                     /gene="nusB"
                     /locus_tag="RxyAA322_RS03870"
                     /old_locus_tag="RxyAA322_07690"
     CDS             complement(10881..11300)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nusB"
                     /inference="COORDINATES: protein motif:HMM:TIGR01951.1"
                     /locus_tag="RxyAA322_RS03870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07690"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_143527005.1"
                     /transl_table=11
                     /translation="MSRRTARKQAFFILYQSDVTGSPGAELLSRWRAYRGELEEYAERV
                     VRGVERERERLDAALDEVSEGWPVWRMSAVDRTILRLALYEMLHVEDVPPEVAINEAVE
                     LAKGFSGEEAPAFVGGVLRGAEDRIFGKVGDGEPG"
     gene            complement(11302..11859)
                     /gene="efp"
                     /locus_tag="RxyAA322_RS03875"
                     /old_locus_tag="RxyAA322_07700"
     CDS             complement(11302..11859)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="efp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006858652.1"
                     /locus_tag="RxyAA322_RS03875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07700"
                     /product="elongation factor P"
                     /protein_id="WP_143527006.1"
                     /transl_table=11
                     /translation="MISTNQFRNGSAIRVDGKRFTILNFQHVKPGKGHAFVRTRLRNMD
                     TGAVIERTFRAGEKVESIRTDSRPMTFLYRDGDLYYFMDQETYEQVAIPEEVVGETKDF
                     ITPNGEVSVLYADGEVVSVEPPAHVELEVVETDPGVRGDTATGGSKPATLETGLVVQVP
                     LFVSVGDRVRVDTRTREYQTRV"
     misc_feature    complement(11929..11945)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.53"
                     /tool="antismash"
     misc_feature    11931..11947
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(11954..13024)
                     /gene="aroB"
                     /locus_tag="RxyAA322_RS03880"
                     /old_locus_tag="RxyAA322_07710"
     CDS             complement(11954..13024)
                     /EC_number="4.2.3.4"
                     /GO_function="GO:0003856 - 3-dehydroquinate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183: 3-dehydroquinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01357.1"
                     /locus_tag="RxyAA322_RS03880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07710"
                     /product="3-dehydroquinate synthase"
                     /protein_id="WP_143527007.1"
                     /sec_met_domain="DHQ_synthase (E-value: 3.6e-88, bitscore:
                     292.6, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARLEVRAGTAYPVEVGFGLDVGELAAAVLEPGECALLTDSTVG
                     PLYAEKVRRSLRGVGWRLLETVEVPAGEGSKSLAVYGDVLRRLARAGLMRDGVLFALGG
                     GVVGDLGGFVAASYMRGIPLVMLPTTLLAMVDSSVGGKAGLDLPEGKNLVGAFLQPRIV
                     IAELGFLESLSGRELSRGLAEVVKMGLLAGGEFFGALERVGAALRREAAALEELVLRSV
                     SFKAAVVAEDERERGRRAILNYGHTVGHGLEAASGYALAHGEAVAVGMVAEALLARRVL
                     GSELVGLHERLLREARLPVRAPGLDAHRVLGAMGRDKKRRGGAHRFVLLEGVGRPVWGV
                     EVGEEEARRAVEAVLG"
     gene            complement(13009..13500)
                     /locus_tag="RxyAA322_RS03885"
                     /old_locus_tag="RxyAA322_07720"
     CDS             complement(13009..13500)
                     /EC_number="2.7.1.71"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004765 - shikimate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013375.4"
                     /locus_tag="RxyAA322_RS03885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07720"
                     /product="shikimate kinase"
                     /protein_id="WP_143527008.1"
                     /transl_table=11
                     /translation="MAIVGYMGCGKSTVGRLLAGRLGAAFVDLDEAVARRAGRSIPLIF
                     AERGEEGFRELEHGELAAALGGGEARVVACGGGAVLREDNRRLLRERAATVFLEEDLRL
                     LYARTRAADRPLRGASFEEFRRRYELRLPLYREVADLTVEVDGRGVEEVAGEIARWLRG
                     "
     gene            complement(13509..14678)
                     /gene="aroC"
                     /locus_tag="RxyAA322_RS03890"
                     /old_locus_tag="RxyAA322_07730"
     CDS             complement(13509..14678)
                     /EC_number="4.2.3.5"
                     /GO_function="GO:0004107 - chorismate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011564440.1"
                     /locus_tag="RxyAA322_RS03890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07730"
                     /product="chorismate synthase"
                     /protein_id="WP_143527009.1"
                     /transl_table=11
                     /translation="MRFGFSTAGESHGPAEVVIVHGVPAGLRLLAEDVDRDLARRQAGY
                     GRGGRQKIERDRVEFLGGVRHGYTLGSPVAMLVRNRDYANWEHRMNPAPVEDPPAPITL
                     PRPGHADLAGMQKYGFGDLRNVLERSSARETVARVAAGAVARRLLEEFGVRISSAVYRI
                     GGVAMDRALAAAGAEKADRSEVRCPDPEVSERMKAEIDAARRARDALGGEFVVVAEGCP
                     PGLGSYADWRDRLDARLARAVVSINAVKGVEIGDAFEAARRRSSEVQDEIVRRGGVLGR
                     ASNRLGGLEGGMTNGEPVVVAAAMKPISTIARALRTVDLSTGEEARAFRERADSCAVPA
                     AAVIGEAMVAVVLAEAFLEKFGGDALEDIRTSYEHYMQRLGLSAHRPDA"
     gene            complement(14712..15227)
                     /locus_tag="RxyAA322_RS03895"
                     /old_locus_tag="RxyAA322_07740"
     CDS             complement(14712..15227)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS03895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_07740"
                     /product="hypothetical protein"
                     /protein_id="WP_143527010.1"
                     /transl_table=11
                     /translation="MAGRRAAEGAARLLETLFRNNRVLPPVLAVVAVFLFTWVAAGSLF
                     GGGEERVASREEPPDAPAPRVEAPDVDSYAAYQSKDPFRQLLQRSETTAEEDAGGFERT
                     EGTGGFERTVPRERTSPGSGAGFRREDTTRRPVRQRPAPPRERTQGLFESGGDLPPPGR
                     VADEARVP"
     gene            complement(15217..15816)
                     /gene="pilO"
                     /locus_tag="RxyAA322_RS03900"
                     /old_locus_tag="RxyAA322_07750"
     CDS             complement(15217..15816)
                     /GO_process="GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /GO_process="GO:0043683 - type IV pilus assembly [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pilO"
                     /inference="COORDINATES: protein motif:HMM:NF016253.4"
                     /locus_tag="RxyAA322_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07750"
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="WP_172620663.1"
                     /transl_table=11
                     /translation="MNGERRTLLIGALGILAAVVLSYLFLLSPLLDRLQSGVQEREQKE
                     AQLARLREEVRRLEDVRRNAPELERQLLELSRRIPERPEIPTFIVQVEEVARASGVTQL
                     SVEPGTPGAPETGGPYSVVPVTMTFEGTYEEMQDFLLRMQNLVRLVTVNEVSYEPAEGA
                     AAGIERLLRVEVRAEIYFQPEGPTPSGTGETTADGG"
     gene            complement(15813..16496)
                     /locus_tag="RxyAA322_RS15410"
                     /old_locus_tag="RxyAA322_07760"
     CDS             complement(15813..16496)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RxyAA322_RS15410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RxyAA322_07760"
                     /product="hypothetical protein"
                     /protein_id="WP_172620664.1"
                     /transl_table=11
                     /translation="MRRINLLPPEERHRGLERLRGQRAAGLLLVGGGAALLLVGLVALF
                     LVVRLYMVESRIAELDAGIAEQNARLEALAPYRGLEAGIREKKPVADGVYRSRFQWAEF
                     LQGLAFVIPTSTALETMSAEASPVDIDAPVGQPLQPPGRVVFTGVSFPEYRNVADFVVR
                     MDNLRYLANTRLESAELDRETFVQPALNFEAEAELVTEVGAAGTGVRLEGLEDQALSGK
                     GGAGR"
     gene            complement(16493..17629)
                     /gene="pilM"
                     /locus_tag="RxyAA322_RS03905"
                     /old_locus_tag="RxyAA322_07770"
     CDS             complement(16493..17629)
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /gene="pilM"
                     /inference="COORDINATES: protein motif:HMM:TIGR01175.1"
                     /locus_tag="RxyAA322_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07770"
                     /product="type IV pilus assembly protein PilM"
                     /protein_id="WP_143527012.1"
                     /transl_table=11
                     /translation="MLDRLTALGRLLPQAIGMDIDRSAIKAVQLSGSPGDYALEHVGYH
                     RLPEGVVSGGEVADPELLAAEIRTFWESHSFRGRSVFLGVANEQVVVRFVSFPRMEPAE
                     LEGALNFQAQDYIPMPLEEAVLDHAVLGPSPENPEEDGVLLVAARKEMVLRFSAALRSG
                     GLRPVGVDVKALCLLRSALPAPFFEDEGDVVLLDVGSELSNLLVAAGGRPSLVRFLPLG
                     VADFVQRVSETADLPADQAEKLVFEPGVGLGGVPDARPALEEEETAELPDPALVYDVRR
                     GLEEASRVLAEEVQRSAEYHRSQPGSREVSLVILSGEAGLIPGITAHLSELLGLPVEPA
                     NPLARISTNRSNVSDEQLRAMEPVLAVALGLAMEDGAG"
     gene            complement(17643..18281)
                     /locus_tag="RxyAA322_RS03910"
                     /old_locus_tag="RxyAA322_07780"
     CDS             complement(17643..18281)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036822.4"
                     /locus_tag="RxyAA322_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07780"
                     /product="hypothetical protein"
                     /protein_id="WP_143527013.1"
                     /transl_table=11
                     /translation="MSQPEAEAQSIGFEEEMRLAIVGAGGYGRLALDVLIAAGISDRVL
                     GFYDDAHAVLPDKVRGFPVLGDIGMLKSMLSVEPVHVIVAITDNRTRLSVANSLRALGG
                     SFFTAVHPAAYISGAAMVGDGSVLAAGAVVHPNAVVGSHTFIGPGALVDRDAEVGAGVW
                     LSAGSVVGPGARVGARALLGFNAGVGRKASVGSDAEVGPLRYVPREGGG"
     misc_feature    complement(18414..18423)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.92"
                     /tool="antismash"
     gene            complement(18436..19356)
                     /gene="fmt"
                     /locus_tag="RxyAA322_RS03915"
                     /old_locus_tag="RxyAA322_07790"
     CDS             complement(18436..19356)
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR00460.1"
                     /locus_tag="RxyAA322_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07790"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_143527014.1"
                     /transl_table=11
                     /translation="MRLAFAGTPEFAATVLRGLLEAGHEIGMVISQPDAPRGRGRRKTP
                     PPVAALAREAGLPLLQPPEISGAAAEISRHDVLVVAAYGQILRPDTLYAARHGAYNVHA
                     SLLPAYRGAAPIERAIMNGERETGVTIIRMDEGLDTGPIALQRRIPIPPEMTGGELADA
                     LARLGAEAIVEVLERLQNGTLNLTEQDSERATYAPRITPGDQEIDWSRSAREVHDRVRA
                     LAPHIGARARHPEVEGPIKIWRTRVHREVGRPMGVGEIRTEEGRIFVGCGEGVVEVLEL
                     QLPGGRRLGAGEFLRGHRLGGALRV"
     misc_feature    complement(18445..18447)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(19365..19844)
                     /gene="def"
                     /locus_tag="RxyAA322_RS03920"
                     /old_locus_tag="RxyAA322_07800"
     CDS             complement(19365..19844)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011564447.1"
                     /locus_tag="RxyAA322_RS03920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RxyAA322_07800"
                     /product="peptide deformylase"
                     /protein_id="WP_172620665.1"
                     /transl_table=11
                     /translation="MRTFGDPVLKSRAAPVEGFDGSLALLAEQMFETMHEHEGVGLAAN
                     QVGRLKRIFVAEVDDRRLVVVNPVIEEVSEETATAEEGCLSIPGVRVEVERPVAVVLTG
                     QDLDGAPLRIEAEGLLARVVQHETDHLNGILILDRVDRETRRAALRQLRERMLGR"
ORIGIN
        1 atccggtggc cggcggtgca cagctcgtgc accgccggcg gagcgagcgc gacccggctc
       61 tcgcccgcgg cgacctcccg caccaccccg accctcaacc gtccacctcc ccgagggcca
      121 gggcgaccgc cgcggccgcc gcgtcgaaga agacgggatc cctctcgtag ccgcgtccca
      181 tgctctcgaa gcttaaaccg aagcgctcct ccaatccagc ggcgccgaag gggacgggga
      241 cgtaccggtg gcgctccggc aggccccgca gctccgcctc cggagcgccc ctggggagcg
      301 ccacccgaca cggggccagc gccgcctcca gaacggagcg ggtgtggtgg gagaggccga
      361 agtggcgggg ccgggggtcc accagggaga tccgcggggc gaggaccggc tcgcccccga
      421 gggcgcaggc ggcgttgagg gcggccgcgg cggccatccc cccgtgcccg tacggggaac
      481 cggtcccgac gaccccgggc cctatcccgg cgagcacgag gtcggccccc gcggccgccg
      541 cgaggagcgc cgcgtagacg ttgggagcct ccacgtcgcc cccgaagcag ttcccggccg
      601 agacgaccac gctcagaagc ccctgctccc ggagcttccg gacgagcacg gagagcccca
      661 cgggcagggc cccgccctcc tgccagacga acgccacccg ccaccccggc cgcagggcgg
      721 cggccgcgca gcaggcaggg gcgaggtgcg agtgcagcgg caggacggcc accggcaccc
      781 cccgcaggct tccggccaac tcctcgggcg gaggggccgg gtgctgcagg ggagtgtacg
      841 gaagcttcac gaaatggtcg cggttctcgg gcacctcccc cgccccgccg ggcgggacgg
      901 ccacggcgag cccgccggtg ccgaggccca tctccagccc cagggtgttg gccaggatct
      961 cttcgccccc gcggggcatc ctccccagct ccgggtagca gacggccgca aagcgccgcc
     1021 cggcgagcgg accctcgagc agctccagct cgaaaatccc gtccgcgtcc ggctctccga
     1081 gcgcaaccgc cctccggagc accgctagag cacctcccag cgcggatgtc tgcgcaggaa
     1141 ggcggcgaga tccccccgct ccccggtccc gacccaggag gccgcgccgg ccggcaccgc
     1201 gctccagcaa tacggcacct cccgtgcgca gaacccggcc gcgagcagat cccggctcag
     1261 ccgccgcagg gttcgtgcgt cggcctcccg gggaggttcg ccgcgaacca cctcgacctc
     1321 ggcgagcgcc ccggagagcg ccgcggcctc catcaccgcc cgcagcacgg tctctagtcc
     1381 ctcccccagc gtgcggcgct cgagcgcccg cacctcgccc cgcagcagcc gcaccccctc
     1441 cccgcggcct gcctcctcga agcgcagaca aaccccctcc ggcagcccgg gcaccgcggg
     1501 gagcagaggc ccccgcggcg cctccccggc gcgccaggaa agctcggcca cgaagctcgc
     1561 caccccagcg gcccggagcg ggagcgtgcc ggcgggctcg gatcgcagca gggcgacccc
     1621 cgtccgcggc gccaagcctc ctaccggacc tcctcttctc cgcccgccgg ggccgcgacc
     1681 ctatcggcgg cccccaggca ggccccgacg aaaccgtaga acagcgggtg gggccgcagg
     1741 gggcggctct tgaactccgg atggaactgg ctcccgatga agaacgggtg gtccctgagc
     1801 tcggctatct ccaccagccg cccgtccggt gaggtgccgc tgaagaccat ccctgcctcc
     1861 tcgagcacct cccggtaggc gttgttcacc tcgtagcggt ggcggtgccg ctcgtggacc
     1921 acctcggcac cgtagaccct ggcggccagg gtgccgggcc gaagcctgca ggggtaggag
     1981 cccaggcgca tcgtgccccc catctcgacc cccacctggt ccggcatgat gtctatgacc
     2041 gggtggggtg tctcctcgtc gaactcggtg gagttcgcca tctccaggcc ggccacgttg
     2101 cgggcgaact cgatgacggc tatctgcagc cccaggcaca gccccaggta cggggtgccg
     2161 ctctcccggg cgtagcgggc cgcctcgatc ttgccttcta tcccgcgttg cccgaagccg
     2221 tggagcacca gtaccccgtc cgccccccgc agccgctccc gggcggattc gggaccggag
     2281 atctgctcgg aatccaccca gtccagctcc acccgaacct cgtgggcccc accggcgtgc
     2341 cggagcgcct cgacgaccga gaggtaggcg tcctgcagcc ggacgtactt cccgatcacc
     2401 gcgacgcgca cctccctcgt ggccccgtgc atcctccgga ccagcgagcg ccactgctcc
     2461 agccgcgccg gcggggacgg cagccccagc ttctccagca ccagggcgtc gagccccgag
     2521 ccgtggaggc tgagcgggat gtcgtagagg gtgggggcgt cctccgccgg gatcacagac
     2581 tccacctcca cgtccccgaa gagggctatc ttcctgcgga tatcctcgcc gatgggcctg
     2641 tccgcccggc agatgaggat gtccggcgag atgcccatct ccctcaggcg ctgggtggaa
     2701 tgctgggtgg gcttggtctt cagctcccca gcggcctcga tgtaggggac gtaggagacg
     2761 tgcacgtaca atacgttctt gcgccccacg tcgttgcgga actgccttat ggcctccaga
     2821 aacggctggc tctcgatgtc cccgacggtc cccccgatct cggtgatcac cacgtccttc
     2881 tcccgcccca gccgcccgat gcgggccttt atctcgttgg ttatgtgcgg gatgacctgc
     2941 acggtggccc cgaggtagtc gccgcgccgc tcccggctta tgacctccca gtagacgctg
     3001 ccggtggtga cgttggagag cctccccagg ttctcgtcca gaaaccgctc gtagtgcccc
     3061 aggtcgaggt cggtctccgc cccatcctcg gtgacgaaga cctccccgtg ctggtagggg
     3121 ttcatggtgc cgggatccac gttgatgtac ggatcgaact tctgcagtac gacccggtag
     3181 ccccggctct tgaggagcat ccccagagcc gcagcgctgg tccccttgcc gatggaggag
     3241 acgacccccc cggtgacgaa gatgtacttg gtcccgctca tctcaggtgc gcccccactg
     3301 atcgaaacgc cgtaatattc ccacctcccg tatgatcccg gatatggaat ggaactccgc
     3361 aaccagggtg agccccagca ccgccgtccc ggcagcccac cagacccagc ccggccccca
     3421 ggccaccaca agacagccga ccgtggcccc ccagacggcc gctcccgtat ctcccagcat
     3481 gatacgccct ctgaggtcaa aataaaacag gctcaccgca ccgcccagta cgcccgcaac
     3541 tccagccaga acctccccag cccctatagc gaggacgggt acgaacagcc cgaggaattt
     3601 gagcgccctc ccgggccgca cgtcgaggag gttggcgagg ttggcgaacc cggcgaggag
     3661 aaaggccgcc gcaagagccg aaaggctcgc cccgtagagc accaccccca cgaccagagc
     3721 cccacccccc atccccacca ccttcacctg cccgcccgtc accctgccgc gcccgagcgc
     3781 ccgcagatgc cccccgaagc cccgcgcctc ctttcccccc atcgcatcgt cggcgaagcc
     3841 caccagcccc gccaggagca gataggccgg agcccataga ggaaggcccg agaggagaga
     3901 gatggacaag gccgtcagta ttatgggtaa aaacgcgagc cctgcggcgg tggggacggg
     3961 gtgggtggcg tagttggggc ggcggggcag gagggggagg agggtggcga gggcgagggg
     4021 ggtgaggagg aggcccgcgg cgaagagagc tgtggctacc atgggaggcg ctctccgcgg
     4081 agggcgcgca gcacgtcccg gccctggcgg gcgcggtgga ggaagccggc gggggtctta
     4141 ccggtgggcc ggtggtggag gggcaggggg agctcggcgg ggacgatgcc ggcgacgagg
     4201 aggtccaggg tcatccccgt ttcggcgccg aagcccgggg cgaggcccgg gagggaatcc
     4261 agggcggcgg ggagcagggc ccgctggccg gagaggggtt cggcggggtg gtggccggtg
     4321 cggcgggaga tctcgtaccg ggcgaggcgt ttgacgaggc cgaagccacc gcgggtcgcg
     4381 ggggggaagg cggcgacggc ggctggggtg tcgggtccga gggcggcgag gagggaggag
     4441 aggtggcggg cggaggcgcc gaggtcggcg tcggcgagga gcaggggggc ttcgggggag
     4501 atcttccggg cgtgcaggat acccagccgg agggcccggc ccttgtcgcc gggggagtcc
     4561 ggaggggcgg ccgggagaac ttgggcgccg agggtgcggg cggttgcggc ggtggcgtcg
     4621 gtgctcccgt cgtcgacgac caggatcagg gcgagcggga tcgaggagag ggcccgaagg
     4681 gtttgcggga ggaggtcttg ctcgttgcgg gcggcgatca cggcgacggg gcggggcatc
     4741 gtgggtctag tcctccggag ggggcgggaa gaagtccgag gccgtctcct tcgtgccgta
     4801 ggagccgtcg tcctcggaga ggatcagctg cacgatcgcc gcgcggccgg cggggtcgtc
     4861 ggcgttgtcc accgagggga cgccggcgct ctggaagagc tccacctccg agcgcgccgg
     4921 gcccgaagcc tcggcggcga ccacccgcac cccggaggag gcgaagagct cgagcatccg
     4981 ggcctgggcc tcgttcaggg cctccggggt tccgggcggg gcgtccgggg ggatcccgcc
     5041 gccgcccacg aagacgatcg cgtcgggcgg gatgccgtcg gcctccggcg agcggagcac
     5101 ctcccgggcg gtggcgaggt aggtctcggc gaggggggtg gtctcgccgc cgggggcgga
     5161 gacctccgag cggtccgcgg gggcctcgag ggtcaccggc cccgagagct cggcaccggc
     5221 ggagagcagg tcgctctgga cgtcctggac cacctctggg tcggcgtagg gccccgagac
     5281 cagcgccacc cgcagcccca ggaggcggcc cgagatcagg tgctccgcca tcccctgcat
     5341 cagctgctcg tcctcggcgg tgcgctccct gaggcgctcc atctgggtct gctggcggtt
     5401 caggcggttg ctgacgtccg ttatctcggc ctgcaggcgg gcgctgatca cgccgcggtc
     5461 cgccatcgcc accccgagca ggatgccgac cgccagcgcc agaaacacgg cgaccagcga
     5521 gatcacgtgg tacctcaggt ccggcacggc tcagatgccc agcagaagac gcaacttgac
     5581 cgccagcagg ctgaagatgt ccgccacccg gtccgaggag tagaccacgg cgctggccgc
     5641 gaacagcccc gccgccgcca gcgcggccag ctgggccgcc gagacccggg ccgggtagag
     5701 cttggagacc cccttggcgt ccaccagacg cggccccacc ttcaggcggg tcaggaaggt
     5761 ggaggaggcc ccctgcctgc ccttgtccag aaactccacc agccccacgt gggtccccac
     5821 cgccacgatg agctccgccc cgcactggtc ggccaggagg atcgccacgt cctccgagag
     5881 cccgggggcg ggcagggtgt cgaagcgccc gacaccgagg ttccggaccc tctcggcacc
     5941 cgggcagcgg ccgtccgggt aggcgtggac caggatgcgc cgggaggcca gaagtccccg
     6001 ctcggagaca gagtccatgt cgccgaagac cagatccggg cgccagccgg cctccagcag
     6061 cgcgtccgcc ccgccgtcca ccgcgacgat gtagggcttg aggtcgcgca ggtagggcct
     6121 gagggccagc aggtcctggc ggtagtcgta gccgcggacc accaccagca cgtggcggcc
     6181 ccggatctcg cgcgccacct cctccggaac cggcagggag gagaacagca gatcctgctc
     6241 ctcccgcatg aaggccaccg tgttgcgggc gaagcgctcg agcgccgccc ccaccgcagc
     6301 ccggctctcg cgcaaccggc gctcggccgt ctctaggtcc aggtgctccc cggcggccac
     6361 caggtgaccc ccgcggtaga gcgcgtcccc ccgcagctcc acctcgtccc cctcctcgac
     6421 ccgctcgaaa accttgcgac ctaccccgtc caggatgtaa accccggcgc gggccaggat
     6481 gaaggcgccc tggctggggt aggaacccgt cgccgaagga gcggcgttca ccaccgccgg
     6541 aaccccgctc tccaccagcg cctcggccgt gagccggtcc aggttctcgt ggtcgatgat
     6601 cgggatggtc ccgggtccca ggcgcgcaag gatgcgcttc gtcttcctgc ccggcaccgc
     6661 caggccggag atcctcaccc ctccgagcgg ttccccggcg ccccagtggt ggaagccctt
     6721 catccccctc cgcccaccag caggttcgag gcgtgggcca gcgaaaccct gtccacccgg
     6781 cccgagagca tccgggccag ctcccgacgc cgctcctccc cctcgacccg ccggatccgg
     6841 gtgaccgtcc tcccggagac ctcctccttg gagaccacca cgtgcgagga ggcctccgag
     6901 gcgatctgcg gcaggtgggt tatggtgatc acctggcacc gcccgcccag ctcgcgcagc
     6961 cggctcccca ccgcggtggc ggtctccccg ccgatgcccg cgtccacctc gtcgaagatg
     7021 taggtcaccg aggggtccgg ctcccgctgg gccagccgga gggcgagcat gatcctggag
     7081 agctccccac ccgaggcgta gcggcgcacc ggaagctccg gttcgccggg gttgggcctt
     7141 atgacgaact ccacccgctc gttgcccgag ggtccgggct cacaggggac gagctcggcc
     7201 ctgaagagcg tcctgtccag cctgagcccc ttcaggttct cctgcaccct ttccgcgagg
     7261 tgtcgggcgg cctcccggcg ggcggccgag atctcctccc cgagctctgc gagccggcgc
     7321 tcctcccgaa agatccactc ctccagccgc cccgtctcct cgtcggcgtt ctccagcccg
     7381 ctcaaccgct cccgcgccct gcgcagatat ccgggaacgt cctccccgta cttccgctcc
     7441 agctcccgca gctccgccag ccggttctcg acctcctcca ggcgttcggg gttcgcctcc
     7501 agctcgtcca gataggcccg cagctcgtac agcacgtccc ccagctccgc cgaggccccg
     7561 gccagccgct ccgccagcgg tcccagatcc ccgtccagcc gcgaggcccg ctccagctcc
     7621 gaggccgccg ccgagaccgc ctccaccgcc ccgccgccct cctccggagc gagcgcggcg
     7681 gccgcggcgg cggccgcctc cagaagcccg gtcacgttgc gcagccgctc ccgctcggcg
     7741 agcagccgct ccatctcctc ccggctgtag ccggaggcct ctatctcccc gatctggtag
     7801 cgcagaaagt ccagctcccg cagccgggcc tccccgctcg cccggatctc ctccagcctg
     7861 cgccgcgcct cctccaccga acgccacagc tccgcccgct cccggagcgc ctccaggccc
     7921 tccggcccca cgaacgcgtc cagcagcgcc agctgctccg ccgggtcggc cagccgggcc
     7981 tgctctcgct gcccgtggta ggagaccagc cgctccccca gcgccgccag gacacgcacc
     8041 cccaccgaga caccgttcac gtagcagcgc gagcgtccgt cggcggtgat ggtccggcgc
     8101 agcagaagac cgtcgcgggg atccacctcc tccgccagat cccccagcgc cgccgggagg
     8161 atctcacgca gcaccccctc ggggagctcg aagagcccct ccatctccgc ccgctcctcc
     8221 cccgcgcgca ccacctccgc gcgcgcccgg ccgcccagca gcagctgcag cgccgtcgcc
     8281 agcagcgtct tgcccgcccc cgtctccccc gtcaccgcgt tcaggcccgg cgagagccgc
     8341 agggtggcgg actcgatcag ggccacgttc cgaacggaga tctccgagag cactacagaa
     8401 aggtcctccg caccgctcgc caccaggtcc agtcgtcggt ccggcctatt ttaacgcttt
     8461 cggccgagag cctgacccgc acggtgtccc cggcgtgcag ttcccgcggc tcctccccgt
     8521 ccagcgagag cagggcgtcc cgctccacga gccgcagctc cgtcacctgc tcctccccga
     8581 gcaccagtgg ccggctgacg agcgcgtgcg gggcgatggg cacgagcacg tagcaccggg
     8641 cgtcgccgga gactatcggg cctccggccg agagggcgta ggcggtcgag ccgagcgggg
     8701 tggcggcgat gaagccgtcg caccggaagg cgaagagctc ctctcccccg acgctcacgt
     8761 cgaccgaggc gatctggtgc ggccgttttt tgaggagcac cgcgtcgttg gccgccgtcc
     8821 gccacgcctc ctcccccacc cgcacgtcga gcttgcggta ctcctgcacc tctatgccgt
     8881 cgcgaaggag cttccccacc ccctcctcca tgtgctccgg cagcatcccg gacatgaacc
     8941 ccacccggcc gaagttgacc cccagcagga ccttgcccgg atagatcctg gaggcccgga
     9001 gcatggtccc gtcgccaccc agcacgaaga cgaggtcaac ctggtctctg ccgtccgggt
     9061 cgtcctcggg ccgggtctct actatctcca cccccccgcg cccgagcgtc ccctcgagcc
     9121 gctttaaata cccggcgtcg accttgcggc tggccacgat ggccacccgc cgcaccgagc
     9181 cgggctcgag ccgcctacag gaggtcaccg ccgacggcct cccgaacctc ccggggcccc
     9241 acccgaccct cctccccccg gagcaggtgc agcagatact cccggttgcc ggaccggcgg
     9301 ccgaagaccg gagactccat cacccccacc gccccgaacc cgaaccgtcc gaagccctcc
     9361 acggcccgca ggacggcctc ttcccgcgcc cccggatcgc gcaccacccc gccacgcgag
     9421 accttctcgg gcccgacctc gaactgcggc ttcaccagca ccaccgcctc ccgcacggag
     9481 cccgcggtct cgaagatccg ggagagcgcg agcacgacgg agatgaacga gaggtcggcg
     9541 acgacgagct ccggcgcgaa gggcagatcc ccggccccca ggtggcgtac gttggtccgc
     9601 tccatcacct ccacccgggg atcccgcctc agccgccagt ccagctggcc gtagcccacg
     9661 tccaccgcca ccacccgccg cgcgccccgg cgcaacagca cgtccgtgaa ccccccggtg
     9721 gaggccccgg catcgaggca cagccgcccc tccacctcca ccccgaagcg ctccagcgcc
     9781 gcctccagct tctccccggc ccgggagacg taggggcgct ccggcgcggc gaggctcacc
     9841 tcctcccccg gcgcgggacg gaagccggcc ttggtcacca cccggtcccc cacccgcacc
     9901 cggcccgcca ggatcatggc ctgcgcccgg gagcgggtct cggcgagccc ccgctccacc
     9961 aggatggcgt cgagccgcct ccccccggac accgcttccc ctagctcccc cggtgccgca
    10021 cgaagagcgc gaggtccctg agcgccgagg tgtcgcccgg gagcccgccc agggcctcga
    10081 gcgcccgccc gcaggctgca tcggcctccc tcctcgcccc atcgagcccg aagacgctca
    10141 cgaacgtcgc cttgccccgc tcggcgtcgc tacccgcccg cttgcccagc cgctcggtcg
    10201 agccggtggc gttgagcacg tcgtcgacta tctggaagca cagcccaagc tccagcgcgt
    10261 accccgagat cgcccgctgc tcctcctccc cggcccccgc caggatcgcc cccacccggg
    10321 cgctggactt tatgagcgcg ccggtcttgt agcggtggat catgaacagc gtctgcggat
    10381 ccacctcccc ggaggccccg gtctgggcca tgtccagcac ctgcccgccg accatcccgt
    10441 tgaccccggt ggagccggcg agctcctgca ccaccgcgag ccgctgctcg caactgccct
    10501 cctgcctgag ggtgatgagc gcgagcgcct ccccgaagaa ggcgtcgccg gccaggatgg
    10561 ccatcgcctc cccgaacttc ctgtggctcg tgggcctgcc cctgcggaag tcgtcgtcgt
    10621 ccatcgcggg caggtcgtcg tggatgaggg agtaggtgtg gatgagctct atggccgcgg
    10681 ccgagggaag aacccgctcc gggtcctcgc cgaagaggcg ggcgctctcc atgcacagga
    10741 ggggcctcac gcgctttccc ccggcgagca gcgagtagcg catcgcctcc tgcagccgct
    10801 cgagcctcgg ctccctggtg aagacgagcc cctccaggta ctcctcgaag atccgccggt
    10861 gccgctccca gcgcccggcg ctagccaggt tctccatcgc ccaccttccc gaagatcctg
    10921 tcctccgccc cccgcagcac ccccccgacg aaggcggggg cctcctcccc ggagaaaccc
    10981 ttggccagct ccaccgcctc gttgatcgcc acctcgggcg gcacgtcctc cacatggagc
    11041 atctcgtaga gcgccaggcg caatatggtg cggtccaccg cgctcatccg ccacaccggc
    11101 cagccctccg agacctcgtc cagcgcggcg tccagccgct cgcgctcccg ctccaccccc
    11161 cgcacgaccc gctcggcgta ctcctcgagc tccccgcggt aggcccgcca gcgcgagagc
    11221 agctccgcac ccgggctgcc ggtgacgtcg ctctggtaga ggatgaagaa cgcctgcttg
    11281 cgcgccgtgc gccggctcat cctaaaccct cgtctggtac tcccgggtcc gggtgtccac
    11341 cctcacccgg tccccgacgc tcacgaacag cggcacctgg accacgagcc cggtctccag
    11401 ggtggcgggc ttgctcccgc cggtggccgt gtccccccgg acgccgggat ctgtctccac
    11461 cacctccagc tccacgtgcg ccgggggctc cacgctcacc acctccccat cggcgtacag
    11521 gacgctcacc tcgccgttgg gggttatgaa gtccttcgtc tcgcccacca cttcctccgg
    11581 gatggcgacc tgctcgtagg tctcctgatc cataaagtag tacaggtcgc cgtccctgta
    11641 caggaaggtc atgggccgcg agtcggtccg gatgctctcc accttctccc cggcccggaa
    11701 ggtccgttct atgacggcac cggtgtccat gttcctcagc cgggtccgca cgaaggcatg
    11761 ccccttgccg ggcttcacgt gctggaagtt gaggatggta aaccgcttgc cgtcgacgcg
    11821 tatggcgctg ccgttcctga actggttggt ggatatcatg cttgtctctc ctctgcttgc
    11881 ttgcgacctg cccgcgacaa aaggcctctg cgtccgttcc ggacggcagt gcgatattat
    11941 cgcacatcgg ctctcagccg aggacggcct ccacggccct ccgggcctcc tcctcgccga
    12001 cctccacccc ccagaccgga cgcccgaccc cctccagcaa cacgaaccgg tgcgccccgc
    12061 cccgacgctt tttgtcccgc cccatggccc cgagcacccg gtgagcgtcg aggcccggcg
    12121 cccgcaccgg cagccgggcc tcccggagca gccgctcatg cagccccacc aactcgctcc
    12181 cgagcaccct ccgggcgagg agcgcctcgg ccaccatccc caccgcgacg gcctcgccgt
    12241 gcgcgagggc gtacccggag gcggcctcga gcccgtgacc cacggtgtgc ccgtagttga
    12301 ggatggctcg cctcccccgc tcgcgctcgt cttcggcgac cacggcggcc ttgaaggaga
    12361 ccgagcggag gacgagctcc tcgagcgccg ccgcctcccg ccggagcgcc gccccgaccc
    12421 gctccagggc gccgaagaac tccccgccgg cgagcagccc catcttcacg acctcggcca
    12481 gcccccggga gagctcgcgc ccggagaggc tctcgagaaa gcccagctcg gcgattacga
    12541 tccggggctg caggaacgcc ccgacgaggt tcttcccctc cggaaggtcc agacccgcct
    12601 tcccgccgac ggagctgtcc accatggcga gcagggtggt cggcagcatg acgagcggga
    12661 tgccgcgcat gtagctggcc gcgacgaagc ccccgaggtc cccgaccacc ccaccgccga
    12721 gggcgaacag gaccccgtcg cgcatcagac ccgcccgcgc cagccgccgc agcacatccc
    12781 cgtagacggc gaggctcttg gagccctcgc cggccgggac ctccacggtc tccagcaacc
    12841 gccagccgac cccccgcagc gagcgccgga ctttttcggc gtacagcggc ccgacggtcg
    12901 aatcggtgag gagggcgcac tcccccggct ccaggaccgc cgccgcgagc tcccccacgt
    12961 ccagcccgaa gccgacctcg acggggtagg ccgtcccggc gcggacctct agccgcgcag
    13021 ccaccgggct atctcccctg cgacctcctc gacccccctg ccgtccacct ccaccgtgag
    13081 gtccgccacc tcccggtaga gggggagccg gagctcgtag cggcggcgga actcctcgaa
    13141 gctggccccc cgcaggggcc ggtccgcggc ccgggtgcgg gcgtagagca gcctcagatc
    13201 ctcctccaga aacaccgtcg ccgcccgttc cctgagcagg cgccggttgt cctcccggag
    13261 cacggccccg ccgccgcagg cgaccacccg cgcctccccg ccccccagcg ccgccgcgag
    13321 ctccccgtgc tccagctccc ggaagccctc ctcgccgcgc tcggcgaaga tcaggggtat
    13381 agaacgcccg gcgcggcggg cgacggcctc gtcgaggtcc acgaaggcag cgcccagccg
    13441 gccggcgagc agccggccca cggtgctctt gccgcagccc atatacccga ctatggccac
    13501 cagatccttc aagcgtccgg gcggtgggcg gagagcccca ggcgctgcat gtagtgctcg
    13561 taggaggtcc ggatgtcctc cagggcgtcg ccgccgaact tctccagaaa ggcctcggcg
    13621 agtaccaccg ccaccatcgc ctccccgatg accgccgcgg ccggcaccgc gcagctgtcc
    13681 gcccgctccc tgaaggcccg ggcctcctcg ccggtggaga ggtccaccgt cctgagcgcc
    13741 cgggcgatgg tcgagatggg cttcatcgcc gccgcgacca ccacgggctc gccgttggtc
    13801 atcccgccct cgagcccccc gagccggttg ctggcccgcc ccaggacccc tccccgccgg
    13861 acgatctcgt cctgcacttc gctggagcgg cgccgggcgg cctcgaaggc gtccccgatc
    13921 tccacgccct ttacggcgtt tatggagacc acggcccggg cgagccgggc gtccagccgg
    13981 tcccgccagt cggcgtagga gccgagcccc ggcggacagc cctccgccac gacgacgaac
    14041 tcgcccccga gggcgtcccg ggcgcgccgg gcggcgtcta tctcggcctt catcctctcg
    14101 gagacctcgg ggtccggaca gcgcacctcg gagcggtcgg ccttctcggc ccccgccgcg
    14161 gcgagagcgc ggtccatcgc cacccccccg atgcggtaga cggcactgga gatccggacg
    14221 ccgaactcct cgagcaaccg ccgggcgacc gctccggccg ccacccgggc gacggtctcc
    14281 cgggcgctgg agcgctccag cacgttgcgc agatccccga aaccgtactt ctgcatcccg
    14341 gcgaggtcgg cgtgcccggg ccggggcagc gtgatcggcg ccggcggatc ctccaccggc
    14401 gcagggttca tccggtgctc ccagttggcg tagtcccggt tgcgcaccag catggccacc
    14461 ggcgagccca gcgtgtaacc gtgacgcacc ccgccgagga actccacccg gtcgcgctcg
    14521 atcttctgcc gcccgccccg tccgtagccg gcctgccggc gggcgagatc ccggtccaca
    14581 tcctcggcga gcagccgcag cccagccgga acgccgtgga cgatgaccac ctccgccgga
    14641 ccgtgggact cgccggcggt ggagaagccg aacctcaacg aaaaacctcg cgagaagaca
    14701 tcccttctag cctacggcac gcgggcctcg tccgcaaccc ggcccggtgg cgggaggtcg
    14761 cccccgctct cgaagagccc ttgggtgcgc tcgcgcggcg gggccggtcg ctggcggacc
    14821 gggcggcggg tggtgtcctc ccggcggaac cccgcgccac ttcccggaga ggttctctcg
    14881 cggggaacgg tccgctcgaa acccccggtg ccctccgtgc gctcgaagcc gccggcatcc
    14941 tcctcggcgg tggtctcgga gcgctgcagg agctggcgga aggggtcctt gctctggtag
    15001 gcggcgtagg agtccacgtc gggggcctcg acccgcggtg cgggcgcgtc gggaggctcc
    15061 tcgcggctcg cgacccgctc ctcgccgcct ccgaacaggg accccgcggc gacccaggtg
    15121 aagaggaaga ccgcgacgac cgccagcacg gggggcagca cccggttgtt ccggaagagc
    15181 gtctccagga ggcgtgccgc tccctccgct gctctcctac ccgccatcgg ccgtcgtctc
    15241 cccggtcccg gagggtgtcg gcccctccgg ctggaagtat atctccgccc gcacctctac
    15301 cctcagaagc cgttcgatgc ccgcggcggc gccctccgcg ggctcgtagg atacctcgtt
    15361 caccgtcacc agccgcacca aattctgcat cctgaggagg aagtcctgca tctcctcgta
    15421 ggttccctcg aaggtcattg taaccggtac caccgagtag ggaccaccgg tctccggggc
    15481 gccgggggtc ccgggctcca cggagagctg ggtcaccccg gaggcccggg ccacctcctc
    15541 cacctggacg atgaaggtgg ggatctccgg ccgttccggg atgcgtctgg agagctcgag
    15601 cagctgccgc tcgagctccg gggcgttgcg ccggacgtcc tcgagacgcc tgacctcctc
    15661 cctgagccgg gcgagttggg cctctttctg ctcgcgctcc tggacgccgg actgcagccg
    15721 gtcgagcagg gggctcagga ggaacaggta ggacagcacc acagcggcga ggatgccgag
    15781 cgcgccgatc aggagcgtcc tgcgctcgcc gttcacctgc cggccccgcc cttcccggag
    15841 agcgcctggt cctccagacc ctccagccgg accccggtgc cggcggcacc gacctccgtc
    15901 accagctcgg cctcggcctc gaagttcagg gccggctgga cgaaggtctc ccggtccagc
    15961 tcggccgact cgagccgggt gttggccaga tagcgcaaat tgtccatccg caccacgaag
    16021 tccgccacgt tgcggtactc ggggaatgag acgccggtga agaccacccg ccccggcggc
    16081 tgcagaggct gcccgaccgg cgcgtcgatg tccaccgggg aggcctcggc ggacatcgtc
    16141 tcaagagcgg tggaggtggg gatcacgaag gccagcccct gcaggaactc cgcccactgg
    16201 aagcgactgc ggtagacgcc gtcggcgacc ggcttcttct cccggatgcc ggcttcgaga
    16261 ccccggtagg gggcgagcgc ctcgaggcgc gcgttctgct cggcgatccc ggcgtccagc
    16321 tcggctatgc ggctctccac catgtagagg cgaaccacga ggaacagggc cacgagcccg
    16381 acgagcagca gcgcggcgcc tcccccgacg agcagcagcc cggcggcccg ctgcccgcgc
    16441 agccgctcca gcccgcgatg gcgctcctcc ggggggagga ggtttatccg cctcatccgg
    16501 cgccgtcctc catggcgaga ccgagcgcca cggcgagcac cggctccatc gcccgcagct
    16561 gttcgtcgga gacgttggag cggttcgtgg agatccgggc cagagggttc gccggttcca
    16621 ccggcagccc cagcagctcg gagaggtgcg ccgtgatgcc ggggatgagc cccgcctccc
    16681 cggagaggat cacgagcgag acctcccgag atccaggctg tgaccgatgg tactcggcgg
    16741 agcgttgcac ctcctcggca agcacgcggg aggcctcctc gagcccccgc cgcacgtcgt
    16801 agacgagcgc cggatccggg agctccgcgg tctcctcttc ctccaacgcc ggccgagcgt
    16861 cgggaacccc gccgagcccc accccgggct cgaagaccag cttctccgcc tgatcggccg
    16921 gaaggtcggc ggtctcggag acccgctgga cgaagtccgc gacgcccaga gggagaaagc
    16981 ggaccagcga gggtcgcccg ccggcggcga cgaggaggtt ggagagctcg ctcccgacgt
    17041 ccagcagcac cacgtcgccc tcgtcttcga agaagggagc ggggagcgcc gaacgcaaca
    17101 gacagagcgc cttcacgtcc accccgaccg gccgcaggcc gccggaccgg agtgccgcgg
    17161 agaaccgcag gaccatctcc ttgcgggcgg cgacgagcaa gaccccgtcc tcctcggggt
    17221 tctccgggga ggggccgagc accgcgtggt ccagcaccgc ctcctccagc ggcatgggga
    17281 tgtagtcctg agcctggaag ttgagggctc cctccagctc ggcgggctcc atgcggggga
    17341 agctcacgaa gcgcacaacc acctgctcgt tggcgacccc caggaacacg gatctgcccc
    17401 ggaaggagtg ggattcccag aacgtccgga tctcggcggc cagaagctcc gggtctgcca
    17461 cctcaccccc ggagacgacc ccctccggga gccggtggta gccgacgtgc tccagcgcgt
    17521 agtctccggg ggagcccgag agctggaccg cctttatcgc gctccggtcg atgtccatcc
    17581 cgatggcctg cggcagcagc cttccgagcg cggttagccg gtcgagcacc catccacccc
    17641 cctcaaccgc cgccctcccg gggcacgtag cgcagcggcc ccacctcggc gtcgctcccc
    17701 acggaggcct tccgccccac cccggcgttg aaaccgagca gcgcccgcgc cccgacgcgg
    17761 gcgccgggcc cgacgacgga gcccgccgag agccagaccc cggcgcccac ctcggcgtcg
    17821 cggtccacca gcgccccggg cccgatgaag gtgtggctgc cgaccacagc gttggggtgc
    17881 acgacggccc cggcggcgag cacggaccca tccccgacca tcgccgcccc cgaaatatag
    17941 gcggccgggt gcaccgcggt gaagaagctc ccaccaaggg cccggaggga gttggccacg
    18001 gagaggcggg tgcggttgtc cgttatggcg acgatgacgt gcacgggctc caccgagagc
    18061 atgctcttga gcatgccgat gtccccgagc acggggaacc cgcgcacctt gtcggggagc
    18121 acggcgtggg cgtcgtcgta gaagcccagc accctgtcgg agatgccggc cgcgatgagg
    18181 acgtccagcg cgaggcgccc gtatccgccc gccccgacta tggcgagccg catctcctcc
    18241 tcgaagccga tgctctgcgc ctcggcctcg ggctgggaca tgccggcggc taattccgga
    18301 ccgaagatct ctgtgctccc ccctcctcgc ttttcgggca gtttagcacc gcaacagcca
    18361 tatacctctc tctccgcgct ccctctcacc tccgcgggag aaaccgcggc gcctcaaaaa
    18421 ctgtatagct tcttttcaga cgcgtaaagc tccgccgagc cggtgccccc tgaggaactc
    18481 accagccccg agccgccgcc ccccgggcag ctggagctcg agcacctcca ccaccccctc
    18541 accacacccc acgaagatcc gcccctcctc cgtccgaatc tccccgacgc ccatcggcct
    18601 ccccacctcc cggtgaaccc gggtgcgcca gatcttgatc ggcccctcca cctccggatg
    18661 acgcgccctg gccccgatgt gcggcgcaag ggccctgacc cgatcgtgca cctcccgcgc
    18721 gctccgcgac cagtctatct cctggtcgcc cggcgtgatc ctgggggcat acgtcgcgcg
    18781 ctcgctgtcc tgttcggtga ggtttagggt tccgttctgg agccgttcca gaacctccac
    18841 aatagcttca gcgccgagcc gggcgagcgc gtcggcgagc tcaccgccgg tcatctcggg
    18901 tggtatgggg atgcggcgct ggagggcgat gggaccggtg tcgagcccct cgtccatccg
    18961 gatgatggtg acgccggttt ccctctcgcc gttcatgatg gcccgctcga tgggggcggc
    19021 gccgcggtag gcgggcagca acgaggcgtg gacgttgtac gcgccgtggc gggcggcgta
    19081 gagggtgtcg gggcggagga tctgaccgta ggccgccacc acgaggacgt cgtggcggga
    19141 gatctcggcg gccgccccgg agatctccgg cggctggagg aggggaagcc ccgcctcgcg
    19201 ggcgagcgcg gcgacggggg gcggtgtctt gcgcctgccc ctcccgcgcg gtgcatcggg
    19261 ctgagagatg accatcccta tttcgtgccc ggcctctaga aggccgcgga gcacggtggc
    19321 ggcgaactcc ggggtgccgg cgaaggccag acgcattctc tctctcagcg gccgagcatc
    19381 cgttcgcgca gctgccgaag ggcggcccgg cgggtctccc ggtccacccg gtcgaggatg
    19441 agtatgccgt tcagatgatc cgtctcgtgc tggacgaccc gggccaggag gccttcggcc
    19501 tctatcctga gcggggctcc gtccaggtct tgtccggtca gaaccacagc caccgggcgc
    19561 tcgacctcca cccggacgcc gggtatggag aggcacccct cctcggccgt cgcggtctcc
    19621 tcggagacct cctcgatgac cgggttgacg actaccaacc gccggtcatc cacttcggcg
    19681 acgaagatcc gcttgagcct cccgacctgg ttcgccgcca ggccgacgcc ctcgtgctcg
    19741 tgcatcgtct cgaacatctg ctcggcgagc agggcgagcg agccgtcgaa gccctccacc
    19801 ggcgcagccc gggacttgag caccgggtcc ccgaaagtcc gcatctcaag agccaatccc
    19861 tctagacctc ctcgggatcc acctcaacac gcaccgagat ccgctccgcc cgcgcaagcc
    19921 gcctcgcgac caaccgcccg gcacgcgccg ccgcagcacg ctcccgggac ctcaggagaa
    19981 gcctccaggc ggatggcccg tcggccgaag gtgcaggcac cggtccccac agctccactc
    20041 ccgactgcag ggcagatctc acccgtgatt ctaccgcacg acgcaccacc tcctccggac
    20101 cacgcaaggt tatggccacg agccccccaa acggcggata gccgagcgcc cgcagccgcc
    20161 cgagctccac ccgggcgaag gacggatagt cgtcgtccac cgcagccctc aatacgggat
    20221 cctccggatg cctcgtctgt attatgagta gacgttcggt ggcctcggcg gcccggtgga
    20281 ggaggcggaa ggcccgttcg cgggctccgg cgggggaggc gaggagtagg tggtcggcat
    20341 cggggaggac cacgcagtcc caccgccggg agagcatggg gtgcggggta ccgacgacga
    20401 cgggggcttc gtcggcccgg aggattcgtc cgccggccag cagaccggta ttatcggtgc
    20461 cgagggagcg ggagagctcc cggcgcaggc gctcgacggc gaggccggcc gggccgaggc
    20521 gtccggagcc gcagtccggg caccgctcgc gggcgggttc ccggcgtccg cagcgggggc
    20581 aggagaggcc gtcggcgaga acggccaggg caaggtggca gcgggggcac cggagggcgg
    20641 caccgcaacc gttgcagacc atcgacgtgg cgtagcccag ccggtttcca accaccccga
    20701 ccctgcggcc ggtaccgagg gcccggcggc aggcctcgag cgccgtccgg ctgagcgggg
    20761 ctcctgagcc gcgcatatcc acgatgcgca cggcgggcca gcgccgctcc gggggaggtg
    20821 ggatctcaca cacccccggg cgcccgtaga gcgcgagaga ggggcagcgg gacagaaaca
    20881 gtgcgccgcc gccctcc
//
