LOCUS       NZ_CP041604            22649 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. S1A1-7 chromosome.
ACCESSION   NZ_CP041604
VERSION     NZ_CP041604.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S1A1-7
  ORGANISM  Streptomyces sp. S1A1-7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007113565.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:07:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,902
            CDSs (total)                      :: 10,801
            Genes (coding)                    :: 10,337
            CDSs (with protein)               :: 10,337
            Genes (RNA)                       :: 101
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 464
            CDSs (without protein)            :: 464
            Pseudo Genes (ambiguous residues) :: 0 of 464
            Pseudo Genes (frameshifted)       :: 185 of 464
            Pseudo Genes (incomplete)         :: 374 of 464
            Pseudo Genes (internal stop)      :: 46 of 464
            Pseudo Genes (multiple problems)  :: 127 of 464
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10470433
            Orig. end                         :: 10493082
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041604.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22649
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="38"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22649
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22649
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12649](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            <320..>461
                     /locus_tag="FNV64_RS55705"
                     /pseudo=""
     CDS             320..>461
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948548.1"
                     /locus_tag="FNV64_RS55705"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="cyclase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEHQTDVMLQVAYAPKGVAETAADKLGFVKRQIPGVLKVQVVHR
                     EP"
     gene            888..3689
                     /locus_tag="FNV64_RS48005"
                     /old_locus_tag="FNV64_48640"
     CDS             888..3689
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671000.1"
                     /locus_tag="FNV64_RS48005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48640"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_143656528.1"
                     /transl_table=11
                     /translation="MEVFSGRPRSPERHPLTGRSRQHRASPLDLRSAAGQVFLLQVVIV
                     VLLVVAAVAAVVLQTARDAVQRGRRESVVAAQSFASAPGTAEALRSRDPTAVLQPRAEE
                     VRKRTDVDFVVAMNTQGIRYTYPYPSEIGKKFVGTIAPALKGRTVVEQAGGPPLPAGKG
                     TAVQAVVPVTDSRGKVVGLVSAGITVKDVAALWLPQLPIILGSGAAALALSMTGTTLVA
                     RRLRRQTHGLAPAELAQLYEHHDAVLHAVREGVLITGTDGRLLLANDEARRLLDLPADV
                     QGRPVRELGLPEPITRLLSSPEAVTDEVHRAGDRLLAVNKRPTYRKADRGGSVVTLRDT
                     TELAVVSGRAEVARERLKLLYEAGVGIGTTLDVGRTAQELADVAAPEFADLVTVDLLDA
                     VLRGWEPTAEGWRHLRRAAIGGEQRMIPVYPLGEVITFSRRTPQMRTLQERRVLLEADL
                     RQAHGWREQDPERARKALECGLRSLVTVPLQARNVPLGVVNFYRTVDSPAFQPEDLSFA
                     EELAARAALAIDNARRFTREHAMAVTLQRSLLPRAQPDQDALEVAWRYLPAEAGVGGDW
                     FDVIPLPGARVAVVMGDVVGHGLHAAATMGRLRTAVHNFSTLDLTVDEVLGKLDDLVLS
                     MDNEENAGDAAEGHEGEGVTGATCLYAVYDPVSEACTMARAGHPEPAVVRPDGTVTCPG
                     VPASTPLGLGGYPFETAEFSLPQGSQLVLYTDGLVEDRTHDIDVGMERLRQALDGSERR
                     TPEETCQAVIDALKPSHSSDDIALLVARTRIFPPSRVAEWDVPSDPAVVPSVRARCRET
                     LREWGLEEAGFATELILSELITNAIRYGLPPVSARLLHGRCLICEVSDGSGTSPRLRRA
                     ATTDEGGRGLFLVAQFAQRWGTRYTTRGKVIWAEQFLHDGTSATPSRTPVDFLLDQFDD
                     LDT"
     misc_feature    3807..3824
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.09"
                     /tool="antismash"
     gene            3825..3947
                     /locus_tag="FNV64_RS56360"
     CDS             3825..3947
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS56360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_275902474.1"
                     /transl_table=11
                     /translation="MGPAATTCSYLGQNRHNAFPSRLKELRVKHVGEHGMPFGS"
     gene            4361..4564
                     /locus_tag="FNV64_RS48010"
                     /old_locus_tag="FNV64_48645"
     CDS             4361..4564
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014144190.1"
                     /locus_tag="FNV64_RS48010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48645"
                     /product="cold-shock protein"
                     /protein_id="WP_143656529.1"
                     /transl_table=11
                     /translation="MAQGTVKLFNPDKGFGFIAPDEGGAYTFGHHSVIDTGCFCSLEEN
                     QRVQFTASRGPKGIQADRVRAL"
     misc_feature    complement(4365..4380)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            4689..5780
                     /locus_tag="FNV64_RS48015"
                     /old_locus_tag="FNV64_48650"
     CDS             4689..5780
                     /EC_number="1.14.19.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118430.1"
                     /locus_tag="FNV64_RS48015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48650"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_346268942.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 3.3e-17,
                     bitscore: 61.7, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDITIRGTGPADHTDMAKPPPGGRGSDYAALSREVKQSGLLKR
                     RPGYYCVKVGANLFLLAAGWAAFALIGQSWWQLLTAAFLAVMFTQTGFIGHDAGHHQIA
                     ASKRVNNVLGRVHADLLIGLSYGWWINKHNRHHSHPNHVDRDPDIADGAIAFTQDHARV
                     RSGAYAWLARHQAWLFFPMLLLEGLALHIAGVRALLDRTGTATSRAAKLAEAGLLTVHL
                     GGYLAAVFLVLSPVQAVCFLVVHQGLFGLYMGCSFAPNHKGMPVFAKDDKIDFLRRQVL
                     TSRNIRGHRFTDFALGGLNYQIEHHLFPSMPRPSLRHAQELVRTFCARHGIAYYETGLL
                     NSYAQVLRHLHAVGGPLRPEMEY"
     gene            6017..6259
                     /locus_tag="FNV64_RS55710"
     CDS             6017..6259
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS55710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_240363564.1"
                     /transl_table=11
                     /translation="MAGYGVATWAGLEEAFTVGELLALAAEAAGGQHHHLVAVQMPVSL
                     VMMTPIARALHGRGPLPAAADVGLRVMASAPAAPR"
     gene            complement(6492..>6830)
                     /locus_tag="FNV64_RS48025"
                     /old_locus_tag="FNV64_48660"
                     /pseudo=""
     CDS             complement(6492..>6830)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026834.1"
                     /locus_tag="FNV64_RS48025"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48660"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELLPLLGKIPAIAGRVGRPRRHPDALPADRGYDHDQYRRLLRARG
                     IRPVIAKRGEPHGTGLGIVRYVVERTIAWLHGFRRLRIRWERRDDIHEAFLGLAVCLIT
                     HRHVQRLC"
     gene            complement(7251..7928)
                     /locus_tag="FNV64_RS48030"
                     /old_locus_tag="FNV64_48665"
     CDS             complement(7251..7928)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041528.1"
                     /locus_tag="FNV64_RS48030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48665"
                     /product="LAETG motif-containing sortase-dependent surface
                     protein"
                     /protein_id="WP_143604147.1"
                     /transl_table=11
                     /translation="MISKRAVTAAAVAATAAVLLASGDAYACSIGDFTAKATCDTSTGE
                     ARAAITITDKDPSGTPADITVRIRMAVGTDGETVGTGHIDHPTAAGASTTILVPWLQGY
                     QWNVSVTAGNLVDERLTDLPISPDTPCVPATSPTSGTPTVGPAPSVSPTAGVTPTSSAA
                     APLASTSSAPSTSASSPVAGTRLAETGGGSDTGLIAGSAAAAIAAGTGVLFAMRRRATA
                     GRH"
     gene            complement(8240..9095)
                     /locus_tag="FNV64_RS48035"
                     /old_locus_tag="FNV64_48670"
                     /pseudo=""
     CDS             complement(8240..9095)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713379.1"
                     /locus_tag="FNV64_RS48035"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48670"
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTAKPSEAWDTAVGVARVRARETRRENPLFLDPFAEAFAAAGSL
                     PVDGKPPRAPVDDAARRRWGPAALGRGRVLDRGPHPLPRRAAARRGRRGLPPGGPARRR
                     HEQPGLPARLAVGDPPVRDRNGGAAGLQGVGAPGRADRSALRADHRTGRPARGLDRCPG
                     RCRARSGAPHGVDRRGPADPPAAGCGRTPARAGGGAVRDRQPDGPDAGSTRCRRALRAG
                     HRHRGVDAGLRDAARPGHLAGRSRVGHPRVHRA"
     gene            9225..9623
                     /locus_tag="FNV64_RS48040"
                     /old_locus_tag="FNV64_48675"
     CDS             9225..9623
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024980.4"
                     /locus_tag="FNV64_RS48040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48675"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_143656531.1"
                     /transl_table=11
                     /translation="MRWLEQDLAEGPVAHGWPGQTWTLSRISTLIGRRSHKGMTFSAIA
                     QMLHRHGFSHQVPACRAVERDEDAVSGWVKRPGRRWKHRGGGLLRGRGGLLDDAAHHAD
                     LGQARAHARHQGARTCAVPVLDRRSGLS"
     gene            9514..>9762
                     /locus_tag="FNV64_RS55715"
                     /old_locus_tag="FNV64_48680"
                     /pseudo=""
     CDS             9514..>9762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676514.1"
                     /locus_tag="FNV64_RS55715"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48680"
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTPPTTRTWARRGRTPVIRVRGRAQCRFSIAALACHKQGERSRLI
                     YRPKRHVDHKRGGRRSFTWTDYRDLLIAAHQQLGTPMV"
     gene            10001..12649
                     /gene="lanKC"
                     /locus_tag="FNV64_RS48050"
                     /old_locus_tag="FNV64_48685"
     CDS             10001..12649
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040503.1"
                     /locus_tag="FNV64_RS48050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48685"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_143656532.1"
                     /sec_met_domain="micKC (E-value: 6e-227, bitscore: 754.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.3e-09, bitscore: 34.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-05, bitscore:
                     23.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADAHFYETPDRLATGVAGAAQGTVPVFETARRPIP
                     EGWATARVGDWLTLTPLGADGAPAAAPAQGWKIHASATRANADRIAAIVWDYCFPRRIP
                     FKFVPGPHLLHLRNTKYAGRDTSGKFVTVYPADEEQLHTVLRELGSLLKGFEGPYILTD
                     LRWHDGPLYVRYGAFARMYVVDDRGSLVPAVRDGSGTLVPDRRAPSFQVPEWVALPAFL
                     EPHLAARNTTTVGELPYRIEKALHFSNGGGVYAGTDTRDGRKVVLKEGRPHAGLASDGA
                     DAIARLEREKRALEAVAGTGVVPEVRDWFTLGDHRFLVMDFVAGRPLNSFFAERHPLLS
                     PDPDPQAVAAYTAWAVSIHRAVECAVEKVHARGIVFNDLHVFNIMVAPDEESVFLIDFE
                     AAAPAEENGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTTLLVVDRGKVAHL
                     AEVIAQQFPDVPREFLDEAVAEITRDVCGTGAPVGGTGAPERVPSAPASRVEPGDWPHS
                     RDSMIKAILASATPERDDRLYPGDVAQFSDGGGLGLAHGAAGVLYALAAAGAERHDEGE
                     RWLLDHTAPAPTGTPLGLYDGLAGVAHTLDLLGHRQRALDLVDGILRERWQHLSSDLQG
                     GLAGLGLVLGRLAATTGESELRERAAEAADLLVRRLAEPAPAAPRRRAGLMRGASGPAL
                     FLLRRYEETGERALLEAAGVALRRDLECCAEREGGAVEVDEGWRTMPYLGDGSVGVGLM
                     LDDYAAHVPDAGAEFARARAGILTAATSRFYVQPGLFQGRAGMILHLARTTAPGATRAR
                     LDEQIAGLGWSAMPYQGQLAFPGHQMMRLSMDLATGTAGALLALAAAFGSGDEGVAAHL
                     PFLPPPHRRPL"
     gene            12731..12847
                     /locus_tag="FNV64_RS48055"
                     /old_locus_tag="FNV64_48690"
     CDS             12731..12847
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="FNV64_RS48055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48690"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_054233519.1"
                     /transl_table=11
                     /translation="MALLDLQTMESDEHTGGGGNSTVSLLSCISAASVLLCL"
     CDS_motif       12731..12790
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMESDEHTGGGGN"
                     /locus_tag="FNV64_RS48055_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12791..12847
                     /prepeptide="core"
                     /locus_tag="FNV64_RS48055_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="24.00"
                     /molecular_weight="1672.0"
                     /monoisotopic_mass="1671.0"
                     /core_sequence="STVSLLSCISAASVLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMESDEHTGGGGN"
                     /leader_location="[12730:12790](+)"
                     /alternative_weights="1690.1"
                     /alternative_weights="1708.1"
                     /alternative_weights="1726.1"
                     /alternative_weights="1744.1"
     gene            13014..14726
                     /locus_tag="FNV64_RS48060"
                     /old_locus_tag="FNV64_48695"
     CDS             13014..14726
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128988.1"
                     /locus_tag="FNV64_RS48060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_143656533.1"
                     /transl_table=11
                     /translation="MSMDPTTGGLLTAASRHSGPRWAALCLVSVATTGAGLLLPAALGR
                     ALDLLLAHAPATRWVLICATLVLLLTGLDACETVLAGTLDARTTAFLRRRVTGHVLALG
                     PRATLRFGPGDLVARLVGNAAQAGTAPGARAALLAALAGPVGGVVALGVIDPWLAAAFL
                     TGAPLLTLLLRSLARDTSTCVADYQRVQGSIASALAEAVGGTRTIRAAGTADRDAERIL
                     RPLPELSRAGRRMWRVQGRAAARAVAVAPLLHLAVVAVAGMLLSRHRLSAGDVLAASRY
                     AVLATGVGVLVGQLSGLVRARTAARRLGEVLAEPAPTHGDRSLPPDGPGHLELRGVSAR
                     RGARTVLDGVDLVVPGGTTLALVGRSGAGKSLLAALAGRLTDPDAGEVLLDGVALPALS
                     RAELRAAVAYAFDRPALLGTTVEDTIALGLRCPSPARVREAARTACADAFVRRLPDGYA
                     TPVADAPHSGGEAQRLGLARAFAQRGRLLVLDDALSSLDTVTEHQVSEAVLGRAATGTR
                     LVVAHRAATAARADTVAWLDAGRVRAVGTHAQLWRRLPGYRAVFGAAGEEAGA"
     gene            15143..>16189
                     /locus_tag="FNV64_RS55720"
                     /pseudo=""
     CDS             15143..>16189
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FNV64_RS55720"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSRSFVFTSVGALAGLCSLAPLLLLPVVPPLVAGVALFAATLRP
                     LARRQEAYLAADEALAENLGAVCPGLRDVTAAGAEDRIAADAGALADAEQRAARGLARW
                     GVARVVCLALGGHLPLVLLLAGTPWLLDHGVTPGAVLGALAYVSQSLLPALTGLIHGLG
                     TSGSRLTVVLRRLTPPPPAVSRPAVTELTPHTPPPCPSTPAVPPALALTSLTFSYGPAC
                     APVVDDLTLALPSGAHLAVVGPSGVGKSTLAGLVAGLLKPVRGDIRICGCRVPGREAAA
                     GRVLIPQEAYVFSGGLRENLAHLRPDPVPEAELLAAAEAVGLTPLLNALGGPGASVDPA
                     TLSAGERQL"
     gene            complement(16472..17080)
                     /locus_tag="FNV64_RS48070"
                     /old_locus_tag="FNV64_48705"
     CDS             complement(16472..17080)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354522.1"
                     /locus_tag="FNV64_RS48070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48705"
                     /product="response regulator transcription factor"
                     /protein_id="WP_143604150.1"
                     /transl_table=11
                     /translation="MIQVLLVHDGCLVRSVLAQWLSREPDLRVDDVPWRRASRHVRALR
                     PDVCAADLDCSDTAGIPPLGELGLRGGGQVLSRLLVLATANRPGLLRRALEAGALGYVD
                     KTGTPEQLLRGIRKVAKGERFVSESLGFGFLKAAEMPLTRRELSVLTLAAEGASVAEIA
                     GSLHLSHGTVRNYMAAITRKTGARNRIDAIRISQSQGWL"
     misc_feature    complement(16631..16633)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16844..16846)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16880..16882)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17282..17551)
                     /locus_tag="FNV64_RS48075"
                     /old_locus_tag="FNV64_48710"
     CDS             complement(17282..17551)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS48075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_48710"
                     /product="hypothetical protein"
                     /protein_id="WP_143656534.1"
                     /transl_table=11
                     /translation="MVPTKPWSRPAAVPLREWALRDRERRGITAAVAKGAQPRKAVPSA
                     DPDERVWRLEARGGAELEASERKLATERDILREAAKYLAGETNW"
     misc_feature    complement(17691..17706)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    complement(17693..17706)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.01"
                     /tool="antismash"
     misc_feature    complement(17760..17777)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            17792..19435
                     /locus_tag="FNV64_RS48080"
                     /old_locus_tag="FNV64_48715"
     CDS             17792..19435
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019059462.1"
                     /locus_tag="FNV64_RS48080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48715"
                     /product="APC family permease"
                     /protein_id="WP_054233521.1"
                     /transl_table=11
                     /translation="MASVDQLAPPSTSQNRSSLRRNVGLIGLLWASAGSIIGSGWLYGA
                     KNAVVAAGPAALISWGIGAVAIVLLAFVHAELGGMFPVAGGTARYPHYAFGGLAGMSFG
                     WFAWLQAATVAPIEVEAMIGYAGHWHFAKSFLNDNGTLTTSGFIVAVILMGVFVAVNFL
                     GVSVLARTNSAATWLKIFVPLLAIFTLAATHFHSSNFTSHGFAPFGSKGVLAAISTSGI
                     VFALLGFEQAIQLAGESRNPKRDIPRAVLGSVAIGTLIYVLLQVVFIGALPGSSFAKGW
                     DKLDFVGISGPFAGLATLVGLGWLTVVLYFDAIVSPGGTGLIYTTSTSRISYGLSKNGY
                     APRVFERTDARGVPVYGLIMSFVTGVVCFLPFPSWQQLVGFITSASVLMYAGAPLAFGA
                     MRRRLPNRERSYRLPLGGVLSPLAFIVASLIIYWSGWQTLEKLGEAIVLGYLLLGGYAL
                     YASKKGLPNAPRISWKSAQWLPVYLLGIGVISWQGTFGGGQGNLPMWTDIAVVAVFSLA
                     IYHWAIRVALPTDAIEQNIEDIEVVDAGGH"
     gene            complement(19568..20664)
                     /locus_tag="FNV64_RS48085"
                     /old_locus_tag="FNV64_48720"
                     /pseudo=""
     CDS             complement(19568..20664)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057186.1"
                     /locus_tag="FNV64_RS48085"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48720"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTPMEADGAGRARYTYRLRVSSSARTALEAEWALARERTPWLRE
                     GSSVPQQQLIRDFGKSRAKAHKDVRERLPQRQRADMPGWKKKREALPTLNYTRRGLRPQ
                     DDRLHLAGGIVLTVVWSRSPPGEPSSVRVYRDSVGHWYASFVVPPRCSRCRRPARCSAW
                     TGA"
     gene            20663..20869
                     /locus_tag="FNV64_RS56700"
                     /old_locus_tag="FNV64_48725"
     CDS             20663..20869
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294498.1"
                     /locus_tag="FNV64_RS56700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48725"
                     /product="Arc family DNA-binding protein"
                     /protein_id="WP_143656535.1"
                     /transl_table=11
                     /translation="MIRFSLRIPADLHEQVTARAAADRRSLNSEILHLLEVALTAPRPD
                     AGSPGGDPASPAPLRGKPDSSPA"
     gene            complement(21067..21762)
                     /locus_tag="FNV64_RS48095"
                     /old_locus_tag="FNV64_48730"
     CDS             complement(21067..21762)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360465.1"
                     /locus_tag="FNV64_RS48095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_48730"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_143656536.1"
                     /transl_table=11
                     /translation="MSHHHAPSASETLAKPLRRDAQRNRDAIVAAARTAFSEQGLGASL
                     EGVAREAGVAIGTLYRHFPTRLDLVETLFNAKYTELLTTAEEAAAMDDAWEGFCRYLEK
                     LCQLQACDRAFNDLVSARLPLHVAGRKMYERTKELGIQIMRNAQEQGVLRGDVTAQDIA
                     FVIWSQAGIIQATRTIAPQAWRRHLHLMLDAFRTEGAHELPEPPLTNQQVDQTLVTLEC
                     TEEDCREQS"
     misc_feature    21842..21857
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            22025..22408
                     /locus_tag="FNV64_RS48100"
                     /old_locus_tag="FNV64_48735"
     CDS             22025..22408
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS48100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_48735"
                     /product="hypothetical protein"
                     /protein_id="WP_143610315.1"
                     /transl_table=11
                     /translation="MNSMTKRVSIALASTALAGGALLGAGGSASAATTPVPVQHTQYVS
                     VTSATSSEQVGRHTDDGRRDDHRGQDTVRYVRAADHEGEAASWRGVSAARWYEDQVDAA
                     TSWHGVSTARWHEDQVVWSLNHS"
     misc_feature    22525..22536
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 cgcgaagcac ctcaccgagg gcagcgcgaa cgggctgacc ctggtcatcg gcagcgactg
       61 gccctccggc gcaacgtact cgggcggctc gtcggccgcc cccgccgaca cccacgccgc
      121 cgtctccaac gcccatgccc agaccgctga cgagtccaag tgcgccaagg tcagcccgta
      181 caagaccgtt cagctcaacg gggtggcgat gaccccggcc caggcatacg ccgcggcgag
      241 cggcaagcag gactccgcgc cgtgatcaac ggggccgcct cctcgcctga agatcacgga
      301 ccctcggggc tcttcgcccc tggacgagca ccagaccgat gtgatgttgc aggtggcgta
      361 cgcccccaag ggcgtcgccg agacggcagc cgacaagctg gggttcgtca agcggcagat
      421 ccccggggtt ctgaaggttc aagtcgttca tcgagaaccg cagccgtgcg ggacggacat
      481 cacgtcccgc acggctttgt gctgccacac gtggggccaa ccgctcttgg tcagttcatc
      541 gggtagccag cccggagcga tgccatgccc gtcggccagt gacagcggac ggaagccgac
      601 atccgcaggg tgctgtgccg cctctggggt gaggaggagg cgaaccccgc gccgccctat
      661 gaagggcatc cccatcagcg gcagcgaggt tgcacaccgc acatgcccag gctggtccag
      721 tacccatcgc aaggcgcacc ccagccaggc cgaggcggac tgaacgccac gccggcggca
      781 tctccctcgg cccaccaccg tcgccctgaa gtgccgaatt cagtcacgcg gcggcgcgac
      841 gaacgtgatc agcgtcggct tccccgcagc ggtgttatga agggtgtatg gaggtatttt
      901 ctgggcgtcc tcggagcccg gaacgtcatc cgctcaccgg acgctcgcgg caacaccgtg
      961 cttccccgct ggacctgcgc agtgcggccg gtcaagtatt ccttctccag gttgtcatcg
     1021 tggtcctgct ggtcgtggcc gcggtggcgg ccgtggtgct ccagacggcg cgcgacgcgg
     1081 tgcagcgggg gcgtcgtgag tcggtcgtcg cggcccagtc gttcgcgagt gctcctggca
     1141 cggccgaggc gctgcggagc cgtgatccga cggcggtgct ccagccgcgg gccgaggagg
     1201 tgcggaaacg cacggatgtg gacttcgtcg tcgccatgaa cacgcagggg attcgttaca
     1261 cgtatcccta tccgagcgag atcgggaaga agtttgtcgg cacgatcgca ccggcgctga
     1321 agggccgtac cgtcgtcgag caggccggcg ggccgcctct gcccgcgggc aaaggaaccg
     1381 ccgtgcaggc ggtggtcccg gtgaccgact cgcgcggaaa ggtggtcggc ctggtctccg
     1441 caggaatcac agtcaaggac gtcgcggcac tgtggctgcc gcagctgccg atcatcctgg
     1501 gcagcggcgc ggccgcgctg gcgctgtcca tgacaggaac gacgctggtg gcccggcggc
     1561 tgcgtcggca gacacacggc ctggccccgg cggagctggc gcagctgtac gagcaccacg
     1621 acgcggtcct gcacgcggtg cgggaaggag tgctgatcac tggcaccgac ggacggctgc
     1681 tgttggccaa cgacgaggcg aggcgtctgc tcgacctgcc ggcggacgtg caggggcgcc
     1741 cggtgcggga gctgggactg ccggagccga tcacgcgtct gctgtcgtcg ccggaggcgg
     1801 tcaccgatga ggtgcatcgc gcaggggacc gattgctggc ggtgaacaag cggccaacgt
     1861 accggaaggc cgaccgagga ggcagcgtgg tgaccctccg ggacaccacg gagctggcgg
     1921 tggtctcggg gcgggccgag gtcgcgcggg agcggctgaa gctgctgtac gaggccgggg
     1981 tggggatcgg cacgacgctg gacgtgggac gtacggcgca ggagctggcc gacgttgcgg
     2041 cgccggagtt cgctgacctg gtgacggtgg acctgctcga cgcggtactc cgggggtggg
     2101 agccgacggc ggagggctgg cggcatctgc gccgggcggc gatcggcggt gaacagcgga
     2161 tgatcccggt gtatccgctg ggcgaagtga tcacgttctc gcgccgaacg ccgcaaatgc
     2221 ggacgctgca ggagcgacga gtcctgttgg aggcggacct gcggcaggca cacggctggc
     2281 gggagcagga tccggagcgc gcccggaagg ccctggagtg cgggttgcgc tcgctggtga
     2341 ccgtaccgct gcaggcgagg aacgtgccgc tgggcgtggt gaacttctat cggacagtgg
     2401 attccccggc gttccagccg gaggatctct ccttcgcgga ggaactggcc gcgcgggcgg
     2461 ccctggccat cgacaatgcc cggaggttca cccgggagca cgcgatggcg gtgacgctgc
     2521 agcgcagtct gttgccgcgg gcacagccag atcaggacgc actggaggtg gcctggcggt
     2581 atctgcccgc ggaggcgggt gtgggcgggg actggttcga cgtcatcccg cttccgggcg
     2641 ctcgggtggc cgtggtcatg ggtgacgtcg tcggtcacgg gctgcacgcg gcggcgacga
     2701 tgggccggct gcgtaccgcg gtgcacaact tctccaccct ggacctcacc gttgacgagg
     2761 tgctcgggaa gctggacgac ctcgtcctca gcatggacaa cgaggagaac gcgggcgatg
     2821 ccgcggaggg ccacgagggg gagggggtga ccggagcaac ctgtctctac gcggtctacg
     2881 accccgtgtc ggaggcctgc acgatggccc gtgcgggaca cccggaaccg gcggtggtgc
     2941 gtccggacgg gacggtcacc tgtcctggcg ttcccgcttc gacgccgctc ggcctgggcg
     3001 gctacccgtt cgagaccgcc gagttctcct tgccacaggg ttcacaactg gtgctgtaca
     3061 ccgacggcct ggtggaggac cgcacccacg acatcgacgt cgggatggag agactgcgcc
     3121 aggcactgga cggttccgag cgccgcactc cggaggagac gtgtcaggcg gtgatcgacg
     3181 cgctgaagcc gtcacactcc tccgacgaca tcgcgctgct ggtggcgcgt acccggatat
     3241 tcccgccctc gcgcgtggcc gagtgggacg tgccgtcgga tccggcggtg gttccctcgg
     3301 tgcgggcgcg gtgcagggag acgttgcggg agtggggact ggaggaggcc ggattcgcca
     3361 cggaactgat cctcagcgag ctgatcacga acgcgatccg gtacggcttg ccgccggtca
     3421 gtgcgcggct gctgcacgga cgctgtctga tctgcgaggt gtcggacggc agtggcacct
     3481 cgccgcggct acggcgggcg gcgaccacgg acgaaggcgg gcgggggctg tttctggtgg
     3541 cgcagttcgc ccagcgatgg ggaacgcggt acacgacccg cggcaaggtc atctgggcgg
     3601 aacagtttct ccacgacggc acatccgcca ccccgagccg gacaccggtc gactttcttc
     3661 tcgaccagtt cgatgatctc gacacgtgag cccgcatggc ccacgagcgt cgcgtcctct
     3721 tctgtgcacg cgccggagac cctgcaccct cgagcacgac gacgcctgag ggcgcgagtt
     3781 tgacctgggc gttcaggaac cgcctccagt tatgtgcttg tgacgtggga ccagcggcaa
     3841 ccacctgttc gtacctcggc cagaaccgcc acaacgcgtt ccccagtcgg ctgaaggagt
     3901 tgcgggtcaa gcacgtcggt gagcacggga tgcccttcgg ctcgtaggtc gccggatggg
     3961 ccgatgggcc gttgctcgtc ctgtccgtcc tcccttccgg ggcccaggac actcacaact
     4021 caccccggaa cgaggtcaca tcacggcatc ggtctgaagc gggcgcgcag tgatgcggag
     4081 tgtccggtcc cttccggacc cggacccgga cccggacccg gaaccaaccc gcccgggcgt
     4141 cgccggaccc ttccccgtcc aaccgggaac cttccaggcg ctccggacgt tgtagcgagt
     4201 ggttgtagtt gaagtttgcg aacgtggaag cgcccgtgga gttctgacag cgggtgcttc
     4261 gccgttctcg ggggttttct tcgacggctg gcggctgaca gcccgggatc gtgcgagcgc
     4321 gcgttctccg cacctctcgc cacctcgaag gagacgtgac gtggctcaag gaaccgtgaa
     4381 gttgttcaat ccggacaaag gtttcggctt catcgccccc gatgagggcg gcgcctacac
     4441 cttcggccac cactcagtga tcgacacggg gtgtttctgc tccctggagg agaaccagcg
     4501 ggtgcagttc accgccagcc ggggccccaa gggcatacag gccgaccggg tccgcgcgct
     4561 ctgagacacc tcattctgag gcagaccccg cgccgcggac ctgcctcgtg ctgcttccga
     4621 acggctgccg cttgcggtgc cccgccgtcg tgtcggaggc agcgcccgtg cacgccgaaa
     4681 ggaacactgt gaccactgac atcaccatcc ggggcaccgg tccggcggac cacaccgaca
     4741 tggctaaacc cccgcccggc ggccggggca gcgactacgc cgcactgtcc cgcgaggtga
     4801 aacagagcgg gttgctgaag cggaggccgg gctactactg cgtcaaggtc ggggcgaacc
     4861 tgttcctgct ggccgcgggc tgggccgcgt tcgccctgat cggacagtcg tggtggcagc
     4921 tgctgaccgc agccttcctc gcggtgatgt tcacccagac cgggttcatc gggcacgacg
     4981 ccggacacca ccagatcgcc gcctccaagc gcgtcaacaa cgtgctcggc cgtgtgcacg
     5041 ccgacttgct gatcggcctc agttacggct ggtggatcaa caagcacaac cggcaccact
     5101 cccaccccaa ccacgtcgac cgcgaccccg acatcgccga cggcgcgatc gccttcaccc
     5161 aggaccacgc ccgggtccgc agcggagcgt acgcatggct ggcccgtcac caggcctggc
     5221 tgttcttccc gatgctgctc cttgaaggac tcgccctgca catcgccgga gtacgggcgc
     5281 tgctggaccg caccggtacc gcaacctcgc gggcggccaa actggccgag gcgggactgc
     5341 tgacggtgca tctcggcggc tatctcgccg ccgtgttcct ggtcctgtct cccgtccagg
     5401 ccgtgtgctt cctcgtcgtg caccaggggc tgttcgggct gtacatgggg tgctcgttcg
     5461 cccccaacca caagggcatg cccgtcttcg ccaaggacga caagatcgac ttcctgcgtc
     5521 ggcaggtact gacctcacgc aacattcggg gccaccggtt caccgatttc gcacttggcg
     5581 gactgaacta ccagatcgaa caccacctgt tcccctccat gccgcggccc agcctgcgcc
     5641 atgcccagga actcgtgcgc accttctgcg cccggcacgg tatcgcctac tacgagaccg
     5701 gactcctcaa ctcctacgcc caagtgctgc ggcaccttca tgcggtcggc ggccccctgc
     5761 gccccgaaat ggagtactga gcaactgccg ccggtgccgg ccgacggaca tacgctgagc
     5821 gtcgtcttga cggagttcgg cgggcacacc actccggtgg ccacgcgccg gcacaccgtg
     5881 tggcaccgac tccatccggc tcgacctggt cctgctgcac aaccccgagc gagcccgccc
     5941 cggcgaccgt tccgccctgc actctgccat ccgggacgcg ttcgcgattc tggaggagga
     6001 ggtgggggcc gggcgcgtgg ctgggtacgg ggtcgccacg tgggcgggcc tggaggaggc
     6061 gttcacggtg ggggagctgc tcgccctggc cgccgaagcc gcgggcggac agcaccatca
     6121 tctggtcgcg gtccagatgc cggtcagcct ggtgatgatg acgccgatcg cgcgggccct
     6181 tcacggccgg ggtccgctcc cggccgccgc cgacgtggga ctgcgggtga tggcgtcggc
     6241 ccccgctgca ccgcggtgag ctccccggta tggtcggcca ggagttcgcc gacctcatcc
     6301 ggccggacct gacccccgca caagcgtgca tcctcgccgt cgcgccatgc ccaggggtga
     6361 cggacgtcct tctggccgcc tccggtgcgc cacagtggaa ggaggcggcc gacgccgtcg
     6421 cccaaccctc cctgaccgcc gccaagttgc gggagtcggc acggcacccg tcgagtatca
     6481 ctttactggt cctaacagag ccgctgtacg tggcggtggg tgatcagaca gacggcgagt
     6541 ccgaggaatg cttcgtggat gtcgtcgcgt cgttcccagc ggatgcgaag gcgtcggaag
     6601 ccgtggagcc aggcgatcgt gcgctcgacg acgtagcgga cgatgcccag gccggtgccg
     6661 tgaggctcgc ctcgcttcgc gatcacgggg cggatcccgc gggcccggag caggcggcgg
     6721 tattggtcgt ggtcgtagcc gcggtcggcc ggcagtgcat cggggtgtcg gcgaggtctg
     6781 ccgacccggc ccgcgatggc cgggatcttg ccgagcaggg gcagaagttc atcgggagcg
     6841 atccaaggcc gcgactgacg tttccccgca accagaccaa cgaacagaca agccaacacc
     6901 cacatgatca acagcttttg ttggagccag ttggcgaaca gacgtggggg atctggtggc
     6961 gatgccctac aggccacaac gtggagcggg tgagatggcg acccgcctcg aacgggtggc
     7021 cgcagggact cccgaactca tcgacattga tcacgcgccg ggcccccgag gtgactcccg
     7081 aatgccccta caaacgcctc ccgttctcgc gttcacagcc ggcccgcaga gctttgaaca
     7141 gttgctaccg cttggaccca tgcaagcggg tgggtcgctg ggcaggggcc gtacgtatcg
     7201 tcagatgcat acgacccctg tcctcggccc ggcccggcgc gggtccgtgg tcagtgccgt
     7261 ccggccgtcg cgcggcggcg cattgcgaac agcacgcccg tgccggcggc gatcgccgcg
     7321 gcggccgatc cggcgatcag accggtgtcg ctgccgcctc cggtctcggc gagcctggtc
     7381 cccgcaacgg gcgaggaagc ggacgtcgaa ggggctgagg acgtcgaggc caacggcgcg
     7441 gcggccgacg aggtcggcgt gacgccggcg gtcggcgaca ccgagggggc cggcccgacc
     7501 gtcggggtgc cggacgtggg ggaagtggct ggcacgcagg gggtgtccgg ggagatcggc
     7561 aggtccgtca ggcgctcgtc gacgaggttg cccgccgtca ctgagacgtt ccattggtag
     7621 ccctggagcc acggcaccag gatcgtcgtg ctcgcacctg ccgccgtggg gtggtcgatg
     7681 tgtccggtgc cgacggtttc gccgtcggta ccgaccgcca tccggatccg cacggtgatg
     7741 tccgcgggcg tgccggaggg gtccttgtcc gtgatcgtga tggcggcccg ggcctcgccg
     7801 gtgctggtgt cgcacgtcgc cttcgcggtg aagtcgccga tgctgcaggc ataggcgtca
     7861 ccagaggcca ggagcacggc agctgttgcg gccacggcgg cagcggtgac ggcacgcttg
     7921 gatatcacgg gtccctcccc agggaacgtt ccacgtgggg tgcccggatc ggggcccccg
     7981 ctggccgcgg gcgcacgccc gcggatggct tcgaggggcc caagggccgg tcggagcggc
     8041 tcatcatgtc acctctcccc acggggaacc tgaacgggcc cctagttgag aggtcaccca
     8101 gctcaaggca acaagccgct gagagggctg cccgtaacgc tgaaggtctc ccggcacatg
     8161 gcggccgaca cctacggtgg acttcaccac gaggcgtagg agaccgccat gagtcaggaa
     8221 ccgcggacgc gcgccgtgct cagcggcgtg ccgcggagat caggacgccg tgcctcggcg
     8281 gctgctcctc gggtgccgtg accgggcgtc cgtacgccgc cgcgcgttca cgcacggtgt
     8341 acgcgcgggt gtcccacccg agaccggcca gccaggtgac cgggtcgggc ggcatctcgg
     8401 agacccgcat cgacgccgcg gtgccggtgt cctgcgcgaa gcgctcgacg acaccgggtt
     8461 gacccagcgt caggcccatc cggctgccgg tcgcggacag ctcccccacc tgcccgagca
     8521 ggcgttcgac cgcatcctgc ggcaggtgga tcagcaggcc ctcggcgatc cacaccgtgg
     8581 ggagcgccgg atcgtgcccg gcagcgacca gggcaccggt ccagtcctcg cgcaggtcga
     8641 ccggtacggt gatccgctcg cagcgcggat cggtcggctc ggcccggagc accgactcct
     8701 tgaagcccag cggctccgcc gtttcgatct cgaacaggcg ggtctccgac ggccagtcga
     8761 gccggtaggc ccggctgttc atgccggcgc cgagcagggc cacctggcgg cagcccgcgt
     8821 cggccccgtc gcgcagcagc tcgtcgagga agcgggtgcg gaccacgatc gagaacgcga
     8881 ccgcgcccca gcgccgccgg gccccagcgc cgccgggccg cgtcgtccac gggcgctcgc
     8941 ggcggcttcc cgtccaccgg caggctgccg gcggcggcaa atgcctccgc gaacgggtcc
     9001 aggaacaagg ggttctcgcg ccgggtctcc cgtgcccgca cccgggcgac cccgacggcc
     9061 gtgtcccagg cctcggacgg cttcgctgtc gtcatgactc gcccctcgtc aacgaggcgg
     9121 cttctcgccc ggctccgttg agccttgacg gccgagccct ggcggggagc atgccctggc
     9181 gtcgaaggga ccggtgtcca ggctcaagct gagagaggcg ctggttgcgg tggctggagc
     9241 aggatctggc cgaggggccg gtggcgcacg gctggccggg ccagacctgg acgctgtcgc
     9301 ggatcagcac cctgatcggg cgccgttccc acaaaggcat gaccttttcg gcgatcgcgc
     9361 agatgctgca tcgtcatggc ttcagccatc aggttccggc ctgtcgtgcg gtggagcgcg
     9421 acgaggacgc cgtgagcggc tgggtgaaga gacctggccg caggtggaag caccgtggcg
     9481 ggggtctgct tcgaggacga ggcgggcttc ttgatgacgc cgcccaccac gcggacctgg
     9541 gccaggcgag ggcgcacgcc cgtcatcagg gtgcgcggac gtgcgcagtg ccggttctcg
     9601 atcgccgctc tggcctgtca taagcagggc gaacgctcac gtctgatcta ccggcccaag
     9661 cggcacgtcg atcacaaacg gggcggcaga cgcagtttca cctggactga ttacagggat
     9721 ctactgatcg ccgcccacca gcagctcggc accccgatgg tgccgatcgt tcccggcgac
     9781 ccgggccgga tgtcgggatc tgtcggcatg ggcctggctc gacgccccac gagagcaacc
     9841 cgcggagcac atgtgtccag gaggcggcgc ggggccgcga tcgaaacgag tcgaacatgt
     9901 ctttacccgt gcgtttcgca cagtgagctc gtgacagtcg tgactgtcgg tgccccaggc
     9961 cggcttgcga gtctcttggg cgggccacgg aaggggaggc atggacaagc ggtacgaggt
    10021 gtacgcgttg gcggacgcgc acttctacga gacacccgac cggctggcga cgggcgtcgc
    10081 aggggcggct caggggactg ttcccgtgtt cgagacggca cgcaggccca tcccggaggg
    10141 ctgggcgacg gcccgcgtcg gcgactggct gacactcacg ccgctcggcg cggacggcgc
    10201 cccggcggcg gcgccggccc agggctggaa gatccacgcc tcggccaccc gggcgaacgc
    10261 cgatcggatc gcggcgattg tgtgggacta ctgcttcccc cgccgcatcc cgttcaagtt
    10321 cgtgccgggc ccgcatctgc tgcatctgcg caacaccaag tacgcgggcc gcgacaccag
    10381 cggcaagttc gtcaccgtct acccggccga cgaggagcag ctgcacacgg tcctgcgcga
    10441 gctgggttcc ctgttgaagg gcttcgaggg cccctacatc ctcaccgacc tgcgctggca
    10501 cgacgggccg ctgtacgtcc gctacggcgc gttcgcgcgc atgtacgtcg tcgacgatcg
    10561 gggttcgctc gtgccggcgg tgcgcgacgg ctcgggcacg ttggtgccgg accggcgggc
    10621 gccgtccttc caggtgccgg agtgggtggc gctgcccgcg ttcctcgagc cgcatctcgc
    10681 ggcgcgcaac accacgacgg tgggtgagct gccgtaccgc atcgagaagg cgctgcactt
    10741 ctccaacggc ggcggagtgt atgccggcac cgacacccgg gacgggcgca aggtggtgct
    10801 caaggagggg cggccgcacg cggggctggc ttccgacggg gcggacgcga tcgcccggct
    10861 cgagcgggag aagcgggctc tggaggcagt ggcggggacc ggggtggtac ccgaggtgcg
    10921 ggactggttc accctcggcg accaccgctt cctggtcatg gacttcgtgg cggggcgccc
    10981 gttgaactcc ttcttcgccg aacggcaccc gctgctctct cccgaccccg acccgcaggc
    11041 cgtcgccgcg tacacggcat gggcggtgag catccaccgg gcggtggagt gcgcggtgga
    11101 gaaggtgcac gcgcgcggga tcgtcttcaa cgacctgcac gtcttcaaca tcatggtcgc
    11161 gcccgacgag gagtcggtgt tcctgatcga cttcgaggcg gccgccccgg ccgaggagaa
    11221 cggccgccag gtcgtggcgc atcccgggtt cttcgcgcca ccggaccgcc ggggcgccga
    11281 cgtcgaccgg tacgcgctgg cgtgtctgcg gctcgccctg tttctgcccg tcaccacgct
    11341 gctcgtggtg gaccggggca aggtggccca tctggccgag gtgatcgcgc agcagttccc
    11401 ggacgtgcca agggagttcc tggacgaggc ggtcgcggag atcacccgcg atgtctgcgg
    11461 caccggggcc cctgtcggcg ggaccggcgc gccggagcgg gtgccgtcgg cccccgcttc
    11521 ccgggtggag ccgggcgact ggccgcacag ccgcgactcg atgatcaagg cgatcctcgc
    11581 ctcggcgacc ccggagcgcg acgaccggct ctaccccggc gacgtcgccc agttctccga
    11641 cggcggcggc ctcggcctcg cgcacggagc ggccggcgtc ctgtacgccc tggcggcggc
    11701 cggcgccgaa cgccacgacg agggcgaacg ctggctcctg gaccacactg ccccggcccc
    11761 gacgggcacc ccgctcggtc tgtacgacgg tctcgcgggc gtcgcccaca ccctcgacct
    11821 gctcggacac cggcagcggg ccctcgacct ggtcgacggc atcctgcgcg aacgctggca
    11881 gcatctgtcc tcggacctcc agggcggcct ggccggcctc ggcctggtgc tggggcgact
    11941 ggccgccacg accggcgagt cggaactgcg cgagcgggcc gccgaggccg ccgacctcct
    12001 cgtacgtcgc ctcgccgaac cggcgccggc cgcgccccgg cgacgggccg ggctgatgcg
    12061 gggcgcgagc gggcccgcgc tgttcctcct ccggcggtac gaggagaccg gcgagcgtgc
    12121 gctgctggag gcggccggcg tggcgctgcg gcgggacctg gagtgctgtg ccgagcgtga
    12181 ggggggcgcg gtggaggtcg acgaggggtg gcggaccatg ccgtatctcg gggacgggag
    12241 cgtgggcgtg gggctcatgc tcgacgacta tgcggcgcac gttccggacg ccggcgcgga
    12301 gttcgcgcgg gcccgtgccg gcatcctcac cgcggccacc tcccgtttct acgtgcagcc
    12361 cggcctcttc cagggacgtg ccgggatgat cctgcacctc gcccgcacca ccgcgccggg
    12421 ggcgacgcgg gcgcggctcg acgagcagat cgccgggctg ggctggtcgg cgatgccgta
    12481 ccagggccaa ctcgccttcc ccgggcacca gatgatgcgc ctttccatgg acctcgccac
    12541 cggaacggcg ggcgcgctgc tcgccctcgc cgcagccttc ggctcgggcg acgagggcgt
    12601 tgccgcgcac ctgccgttcc ttccgccgcc gcatcggcgg cccctatgac atggctctgc
    12661 catccggcgg agtcgtgacg caaccctgtc cccacgggac gaacaaccga caccgacgaa
    12721 aggacacacc atggccctgc tcgacctgca gacgatggaa tccgacgagc acaccggcgg
    12781 cggcggcaac agcaccgtca gcctcctgtc gtgcatcagc gcggccagcg ttctgctctg
    12841 tctctgacga agcggtgccg aacgctctga cgaacggctc acgctgaaca ctccgggcgg
    12901 tcccgctccc gcgagggatg gggccgcccg gggtcgtccg cccgatcggg cggaaacgca
    12961 gaaacgcaga aacgcagaaa cgcagaggcg cggtagctcc gagggggtgc gcgatgtcga
    13021 tggacccgac gaccggtgga ctgctcaccg cggcgagccg gcacagcggg ccccgctggg
    13081 cggcgctctg cctggtgagc gtggcgacga caggcgcggg actgctgttg cccgccgccc
    13141 tcggccgggc tctggacctc ctgctcgccc acgccccggc gacccgctgg gtgctgatct
    13201 gcgcgactct cgtcctgctg ctgaccgggc tcgacgcgtg cgagaccgtg ctcgccggca
    13261 ccctcgacgc ccgcaccacc gccttcctgc gccgccgggt gaccggtcac gtcctggccc
    13321 tggggccgcg tgcgacgctc cgcttcggcc ccggcgacct cgtcgcgcga ctcgtgggaa
    13381 acgccgccca ggccggcacg gcgcccggcg cccgcgccgc gctcctggcc gcactcgccg
    13441 gcccggtggg gggcgtggtc gcgctcggtg tgatcgaccc gtggctcgcg gccgcgttcc
    13501 ttaccggcgc gccgctgctg acgctcctgc tgcgctccct ggcccgggac acctcgacgt
    13561 gcgtggccga ctaccagcgg gtgcagggga gcatcgcgtc cgcgctagcc gaggccgtcg
    13621 gcggcacccg caccatccgc gcggcgggca cggcggaccg ggacgcggaa cggatcttgc
    13681 gaccgctgcc cgaactctcc cgggcaggtc ggcggatgtg gcgggtacag gggcgggcgg
    13741 cggcgcgggc ggtggcggtg gcgcctctgc tgcacctcgc cgtcgtggcc gtggcgggca
    13801 tgctgctcag ccggcaccgg ctctccgccg gagacgtcct ggcggcctcc cgctacgcgg
    13861 tcctcgccac cggggtcggc gtgctggtcg ggcagctctc cggcctggtc cgcgcccgca
    13921 cggcggcccg ccgcctgggc gaggtcctgg ctgaacccgc ccctacgcac ggggaccgga
    13981 gcctgccgcc cgacggcccc ggccacctgg agctgcgcgg ggtgagcgcc cgacgcggcg
    14041 cacgcacggt gctcgacggc gtcgacctcg tcgtgcccgg cgggacgacg ctcgccctgg
    14101 tcggccgctc cggtgcgggc aagtcgctgc tggccgcgct cgcgggtcgg ctcaccgacc
    14161 cggacgccgg cgaggtgctg ctggacggcg tcgcgctgcc cgccctctcc cgcgccgaac
    14221 tgcgcgcggc ggtcgcgtac gccttcgacc gccccgccct tctgggcacg accgtcgagg
    14281 acacgatcgc cctggggctg cgctgccctt ctcccgcccg cgtccgggag gccgctcgta
    14341 cggcctgcgc cgacgcgttc gtccgccgcc tgcccgacgg ctatgcgacg cccgtcgccg
    14401 acgccccgca ctccggcggc gaggcccaac gcctgggcct cgcccgggcg ttcgcccagc
    14461 gcggtcgtct gctcgtcctc gacgacgcgc tctccagcct cgacacggtg accgagcacc
    14521 aggtctccga ggccgtcctg ggcagggccg cgaccggcac ccggctggtg gtggcccacc
    14581 gggccgcgac ggccgctcgt gccgacacgg tggcatggct ggacgcgggg cgggtccggg
    14641 cggtgggcac gcatgcacag ctgtggcggc ggctgcctgg ctaccgggcg gtgttcgggg
    14701 ccgcagggga ggaggcagga gcgtgacgca ccgggacgga ctccaccggc tgcacggaga
    14761 cctgggccac cgcgccctgc tcgccctgcg ctttttgtac gtcggccgac gggcgatggt
    14821 gcggctcgcc ggctggtcgg tgctggagac gggtcagacg ttcctcctcg gctacgccct
    14881 cgcgcgtgca ctggacgacg ggttcctggc cggacgggcc gccgtggggc tcggctggct
    14941 cgcggcagcc gggctcggcg tactcgtcgg cgcgtacggc accgggcggg tgtacggggc
    15001 ggtcgccgcg ctggtggagc cgctcaggga caggctcgtc accggcgtgg tgcggcgcgg
    15061 ggtgcgggag ggggaccgcg gggcgctgtc cggcctgacc cagcaggtcg agatcgcccg
    15121 ggacaccttc gccggcctgg tgatggtctc gcgctcgttc gtgttcacgt ccgtcggcgc
    15181 gctggcgggc ctgtgctcgc tcgccccgct gctgctgctg cccgtcgtgc cgccgctcgt
    15241 cgccggagtg gctctgttcg cagcgaccct gcgtccgctg gcgcgacggc aggaggcgta
    15301 cctcgccgcc gacgaggccc tggcggagaa cctgggcgcc gtctgcccgg ggctgcggga
    15361 tgtcacggcg gccggcgcgg aggaccggat cgccgcggac gccggcgccc tcgccgacgc
    15421 cgagcagcgg gcggcccgcg gcctggcccg ctggggcgtg gcccgcgtcg tctgtctcgc
    15481 actcggcggc cacctgcctc tggtcctgct cctggccggc accccctggc tcctcgacca
    15541 cggggtcacc cccggcgccg tgctcggcgc gctcgcctac gtcagccagt cgctcctccc
    15601 cgccctcacc ggcctcatcc acggcttggg caccagcggc tcgcgcctga ccgtggtgct
    15661 gcgccggctg acgccgcccc cgcctgcggt ctcccgcccc gccgtcaccg agctcacccc
    15721 gcacaccccg cctccgtgcc cctccacccc ggcagtgccc ccggccctcg cgctcacgtc
    15781 cctcaccttc tcctacggcc ccgcctgcgc ccccgtcgtc gacgacctca ccctcgcgct
    15841 gcccagcggc gcccatctgg ccgtcgtagg gccgagcggt gtcgggaagt ccacgctggc
    15901 cgggctggtc gcgggactgc tgaagccggt acgcggagac atacggatct gcgggtgccg
    15961 ggtgccgggc cgtgaggccg ccgccgggcg cgtgctgatc ccgcaggagg cgtacgtgtt
    16021 cagcggcggc ctcagggaga acctcgccca tctgcggccg gatcccgtcc ccgaggcgga
    16081 gttgctcgcc gcggccgagg cggtggggct cacaccgctg ctcaacgccc tgggcgggcc
    16141 gggggcgagc gtggatccag cgacgctgtc ggccggggag cgccagctga tcgcgctcac
    16201 gcgggcgtac ctgtcgtccg cccccctcgt cctgctggac gaggcgacct gccatctgga
    16261 cccggtggcg gaggaacggg cggagcgggc gttcgcggcc cggccgggcg gcaccctggt
    16321 ggtcgtggcc caccgcatca gctcggcccg ccgcgccggc cgggtgctgg tgatggacgg
    16381 cccgcgcacg gccttcggga cgcatgagga ggtgctgcgc cgctcgcccc tctaccgcga
    16441 cctcgtgggt ggctgggaac ccgggcagct ctcacagcca gccctggctc tgggagatgc
    16501 ggatggcgtc gatgcggttg cgggcgccgg tcttgcgggt gatggccgcc atgtagttgc
    16561 gcacggtccc gtgggacagg tgcaggctcc cggcgatctc cgcgacggag gccccctcgg
    16621 cggcgagggt taacacgctc agctcccggc gggtcagcgg catctcggcg gccttgagga
    16681 atccgaaccc cagcgactcg ctgacgaaac gttccccctt agcgaccttc cggattccgc
    16741 gcagcagctg ctcgggcgtc cccgtcttgt cgacgtagcc cagcgcgccc gcctcaaggg
    16801 cccgtctcag caggccaggc ctgttcgcag tggcaagtac gagtaagcgg gacaggacct
    16861 ggccgccgcc ccgcagacct aactcgccca ggggcggaat gccggccgtg tccgagcagt
    16921 ccagatccgc cgcgcacacg tcgggccgca acgcgcgcac gtgacgggac gcccggcgcc
    16981 aggggacgtc gtccacccgc aggtcgggct cccgtgacag ccactgcgcg aggaccgatc
    17041 tgacgagaca tccgtcgtgc acgagaagta cctggatcac tgccgcccct tcaacctgcc
    17101 gtacgccagt cctgtgatgc tgagcgcgtg cccattgttg ggcccccgca acatttctga
    17161 gcgcgaagaa ccagccatca ggatgcgagg gggcgcacgc gcagcacccg cacgccgcgg
    17221 cgtgcttccg gcttcacctc gtaggtgtcc cgatggtcgt caacgaaccg gaagcggctc
    17281 ctcaccagtt cgtctctccg gcgagatact tggccgcctc gcggaggatg tcccgctcgg
    17341 tggcgagctt gcgctcactt gcctcgagct cggccccccc ccgggcctcc aaccgccaca
    17401 cccgctcgtc cggatcagcg gacggcaccg ccttccgagg ctgggcgccc ttcgcaaccg
    17461 cggcggtgat gccacggcgt tcacggtccc gcaacgccca ctcacgcagg ggaactgcgg
    17521 ccggccgcga ccacggcttg gtcggcacca cggcgacgac tgcatcctga tcatggtttc
    17581 gccgccaggg tcagatgcac gccggcgggt cgccgcacgg gatccaccac gtccagcggt
    17641 ggtcaccgag ccgcgcagac gatcatgagc agacgatcat gaatggacgt gatgaaaata
    17701 accattcagc tgtatgggct gttgcatggt gacattccga acctagcctg tggcgactct
    17761 taacgcacca ctaacactgc gaggccgccc catggcatct gtcgaccagc tcgccccacc
    17821 aagcacgagc cagaaccgca gctccctccg acggaacgtc ggactgatcg gactgctctg
    17881 ggcgtccgcc ggctcgatca tcgggtccgg ctggctgtac ggcgcgaaga acgccgtcgt
    17941 cgccgccggc ccggcggctc tgatttcctg gggcatcggc gcggtcgcga tcgtgctgct
    18001 ggcgtttgtc catgccgagc tgggtggaat gttccccgtc gccggcggta ccgcccgtta
    18061 cccgcactac gccttcggcg gcctggcagg catgtccttt ggctggttcg cctggctgca
    18121 ggcggcaacc gtggcgccga tcgaggtcga ggccatgatc ggctacgccg gtcactggca
    18181 cttcgccaag agcttcctca atgacaacgg caccctgacg acgagcggct tcatcgtcgc
    18241 ggtgatcctc atgggcgtct tcgtcgccgt gaacttcctc ggtgtctcgg tgctggcccg
    18301 gaccaacagc gctgccacct ggctgaagat cttcgtgccg ctgctcgcca tcttcaccct
    18361 cgctgcgacc cacttccaca gcagcaactt cacctcgcac ggcttcgcgc cgttcggctc
    18421 caagggcgtg ctcgccgcga tcagcaccag cggcatcgtc ttcgccctcc tcggtttcga
    18481 gcaggcgatc cagctggcgg gcgagagccg caaccccaag cgcgacatcc cccgcgcggt
    18541 gctcggctcg gtggccatcg gcacgctgat ctacgtcctg ctgcaggtcg tcttcatcgg
    18601 cgcgctgccc ggcagcagct tcgccaaggg ctgggacaag ctcgacttcg tcggtatcag
    18661 tggccccttc gcgggtctgg ccacccttgt cggtctgggc tggctgaccg tggtgctgta
    18721 cttcgacgcc atcgtctccc cgggcggcac cggtctgatc tacaccacct ccacctcccg
    18781 tatctcctac ggtctgagca agaacggcta cgcgccgcgc gtcttcgagc gcacggacgc
    18841 acgcggggtc ccggtgtacg gcctgatcat gtccttcgtc accggcgtgg tctgcttcct
    18901 gccgtttccg agctggcagc agctggtcgg cttcatcacc tccgccagcg tgctgatgta
    18961 cgcgggcgcc ccactggcct tcggcgcgat gcgccggcgc ctgccgaacc gtgagcgcag
    19021 ctaccggctg ccgctcggcg gtgtgctctc cccactggcg ttcatcgttg cgagcctgat
    19081 catctactgg agcggctggc agaccctgga gaagctgggc gaagcgatcg tcctgggcta
    19141 cctcctgctc ggcggctacg ccctctacgc gtccaagaag ggcctgccga acgctccgcg
    19201 gatcagttgg aagtccgccc agtggctgcc ggtctacctg ctcggcatcg gtgtgatttc
    19261 ctggcagggc accttcggtg gcggccaggg caacctgccg atgtggacgg acatcgccgt
    19321 cgtggccgtg ttctccctgg cgatctacca ctgggcgatc cgcgtggccc tgccgaccga
    19381 cgcgatcgag cagaacatcg aggacatcga ggtcgtcgac gcgggcggcc actgacccgt
    19441 ccgcactccc tcataccggg gcggtcccga agcggccggt tccaggacag gacagcacac
    19501 tgtcccggct ttgactgctc cccgcctgaa gggatgggat cccttccttc aggcggggat
    19561 tcctggctca ggctgcctct gggagcagtg ctcccggtgg tcttgcgccc tcggcaccag
    19621 ccgggttcag acctgcccgg acgagcatca cgcgggcgga gttcttgtct ctgggggaga
    19681 cgactccgca tgcggtgcag gtgtaggtgc gctcggacaa cggcagtgcg tgcttggttc
    19741 ccgctccgca cgatgcgcag tccatggtgg tgtgcgcggg atgcacgaga cggatgtccc
    19801 gtccgtgctt gcggcccatc tcgaccaggg ccttcttctt ggcgccgagc gcggcgtccg
    19861 gcgccttgcg cgccatcgag gacctggcga ggaacttcgg gctgaagtcc tcgacggcga
    19921 tggcgtcgtg gtcggtcacg gcctgattcg cccacttgcg gccggtgtcc tgccgctgcc
    19981 gggcgatctt cgcgtaggtc ttcgcccgcc acttcttcgc ctcgcggtag cccttcgagg
    20041 cggcctgccc cttcttcggc cggcggcggg ccatcatccg gtcgtaacgg gtcaggccag
    20101 cctgcgcctt acggccgtgc tgggcgtgcg gcaggtcgtg ggcgttggag gtggtggtct
    20161 ccttcacgcc ccagtccacg ccgagcacct ggccggtctc cggcagcggc tgcacctcgg
    20221 tgggaccacg aacgatgcgt accagtgccc gacgctgtcc cggtacacgc gcaccgagga
    20281 aggttcgccc ggcgggctgc gcgaccacac caccgtcagc acgatcccac ccgccaaatg
    20341 caggcggtcg tcctggggcc gcaacccgcg ccgggtgtag ttcagcgtcg gcaaggcctc
    20401 gcgcttcttc ttccaccccg gcatatcggc ccgctgccgc tgaggcaggc gttcccggac
    20461 gtccttgtgt gccttcgcgc gggacttgcc gaagtcccgg atcagctgct gctgaggaac
    20521 tgagctgccc tcacgcagcc acggcgtacg ctcccgcgcc agtgcccact ccgcctccag
    20581 cgcggtacgg gcactcgacg acacgcgaag ccggtaggtg taccgggcgc gcccggcccc
    20641 gtcggcttcc atgggcgtcg tcatgattcg cttctcactc aggatcccgg cagacctgca
    20701 cgaacaggtg accgcccgcg ccgctgcgga ccggcggtcc ctcaactccg agatcctcca
    20761 cctcctggag gtcgccctca ccgctccccg gcccgacgcc ggatcacccg gcggcgatcc
    20821 ggcttcccct gccccgctcc gcgggaaacc ggattcctcc ccggcctgaa ggcctgggca
    20881 tcctccggga atcccggtga cagcgcgggc cggggcagcc ggaagacggc ggtcggacgg
    20941 cccgtggtcc tgccgcccgg agtgctgtcc ggggtcgtcc cggccggtcg tccgaggtac
    21001 tggtccggtg tggcgccggt ccggtgtgat gcgcagctgt tgtccgcggc cttgtctctc
    21061 gtgtggtcag gactgctcgc ggcagtcctc ttcggtgcac tccagagtga cgagggtctg
    21121 gtcgacctgc tggttggtca gagggggttc gggcagttcg tgggcgccct cggtgcggaa
    21181 ggcgtcgagc atcaggtgga ggtggcgacg ccaggcttgg ggggcgatgg tgcgtgtggc
    21241 ctggatgatc ccggcctggg accagatcac gaaggcgatg tcctgcgcgg tgacgtcgcc
    21301 gcgcaggacg ccctgttcct gggcgttgcg catgatctgg atgccgagtt ccttggtgcg
    21361 ttcgtacatc ttgcggccgg ccacgtgaag gggcagccgt gccgagacca ggtcgttgaa
    21421 ggcgcggtcg caggcctgca gctggcagag tttctccagg tagcggcaga acccctccca
    21481 ggcgtcgtcc atggcagcgg cttcttccgc ggtggtgagc agttccgtgt acttcgcgtt
    21541 gaagagtgtt tcgaccaggt cgagccgtgt ggggaagtgg cggtagagcg tgccgatcgc
    21601 gacgccagcc tcgcgggcga cgccctccag ggacgccccg aggccctgct cggagaaggc
    21661 cgtgcgggcg gcggccacga tcgcgtccct gttgcgctgt gcgtcacggc gcaggggttt
    21721 cgccagtgtc tcgctcgcgg acggggcgtg gtggtggctc atggctcgag cgtaacatga
    21781 ggcccccctc gaattcgatt gtcgtcatgt ttccgatcgc aatctcactc ctctgacgtg
    21841 ctgtgatgag cctcactgca aacatgaggc acccctcggg tacggtggca gagccgaacg
    21901 tgaggcaccc ctccggatga ccttgcggca agccgactga cccgggattt ccggatctcg
    21961 gttcacatag aagcggcggc cgccaactcg gcgaaaccgc ggcagtctcg caagggaatt
    22021 gaccatgaac agcatgacca agcgcgtctc gatcgcactc gcctccacgg cactggccgg
    22081 cggagccctt ctcggcgccg gcggctcggc gtcggcagcc acgactccgg tgcccgtgca
    22141 gcacacgcag tacgtgtccg tcacctccgc gaccagcagc gagcaagtcg gccgccacac
    22201 ggacgacggc cgccgcgacg accaccgtgg gcaggacact gtgcgctacg tacgggctgc
    22261 ggaccacgag ggcgaagcgg cctcgtggcg cggcgtcagc gccgcccgct ggtacgagga
    22321 ccaggtcgac gcagcgacct cgtggcacgg tgtcagcacc gcccgctggc acgaggacca
    22381 ggtcgtgtgg tccctgaacc acagctgacg cggcccgagc cgccccactc cggaacgccg
    22441 gcgcctgccc acacagcaac acggccgcac ccccggccga ccaggatccc ggatcgtgcg
    22501 ccccacggcg gtccacaccc gcacggagac gaacgccgca cgcaaggcga aggcactctg
    22561 gccctcagcg ccggccacgc cgaccacggc caggcccgca ccgacacatg aacctcgtca
    22621 accgcttccc ttgccgatcg cttccccac
//
