LOCUS       NZ_CP041604            21302 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. S1A1-7 chromosome.
ACCESSION   NZ_CP041604
VERSION     NZ_CP041604.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S1A1-7
  ORGANISM  Streptomyces sp. S1A1-7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007113565.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:07:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,902
            CDSs (total)                      :: 10,801
            Genes (coding)                    :: 10,337
            CDSs (with protein)               :: 10,337
            Genes (RNA)                       :: 101
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 464
            CDSs (without protein)            :: 464
            Pseudo Genes (ambiguous residues) :: 0 of 464
            Pseudo Genes (frameshifted)       :: 185 of 464
            Pseudo Genes (incomplete)         :: 374 of 464
            Pseudo Genes (internal stop)      :: 46 of 464
            Pseudo Genes (multiple problems)  :: 127 of 464
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4705921
            Orig. end                         :: 4727223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041604.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21302
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="15"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21302
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21302
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11302](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(492..506)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(954..969)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(1061..1076)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            complement(2388..3125)
                     /locus_tag="FNV64_RS22650"
                     /old_locus_tag="FNV64_23005"
     CDS             complement(2388..3125)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382060.1"
                     /locus_tag="FNV64_RS22650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23005"
                     /product="hypothetical protein"
                     /protein_id="WP_143601649.1"
                     /transl_table=11
                     /translation="MAEYEGVDALLAAITDEALPEGAGDDPEFLAEHRSAVADVALLRE
                     QLAVIGDALADRAQEAKPVPVRAPRKRTRRPEGAPRNRGRRPLALVLGTLVAATVAAMV
                     VGMGWILAHNGAGASDSSGAKAADSGTAGGGASLSAPGYLACARLVAEGTVAHVEPLPG
                     TTENRITLHVDRYYKPEKGRAEVVLVLDEEVAPRPREGERVLVAVQGDPATPTGWTTGD
                     KAIADERAWIVKALPASRTLTCP"
     gene            complement(3127..3648)
                     /locus_tag="FNV64_RS22655"
                     /old_locus_tag="FNV64_23010"
     CDS             complement(3127..3648)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116428.1"
                     /locus_tag="FNV64_RS22655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23010"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_054231760.1"
                     /transl_table=11
                     /translation="MLRRKARRVQGADDPLDAAQERRVRAVLALGGVPQADLPDGVQQV
                     RLRLLERAAKGDEAPRDVSAWAAVVASNLAMDWHRAKRRQERLGERLASLRQPADARDE
                     DSSVLSLAVARGLDELPDAQRQVLVLRFYADLSVRGIAEELGIPEGTVKSRLHSAVRAL
                     RARLHEDEVV"
     gene            3943..4959
                     /locus_tag="FNV64_RS22660"
                     /old_locus_tag="FNV64_23015"
     CDS             3943..4959
                     /EC_number="1.2.1.11"
                     /GO_function="GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063171.1"
                     /locus_tag="FNV64_RS22660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23015"
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="WP_054231761.1"
                     /transl_table=11
                     /translation="MRVGIVGATGQVGTVMRRILVERKFPVEELRLFASARSAGTVLDG
                     VTVEDAATADYSGLDIVLFSAGGATSKALAEKVAAQGAVVIDNSSAWRKDPQVPLVVSE
                     VNPHAIADRPKGIIANPNCTTMAAMPVLKPLHEEAGLEALVVATYQAVSGSGLAGVAEL
                     HGQVLKVAADADKLTHDGGAVDFPEPGVYKRPIAFNVLPLAGSLVDDGLHETDEEQKLR
                     NESRKILEIPALKVSGTCVRVPVFSGHSLQVNARFARPLSVERATELLAGAPGVTLSEI
                     PNPLEAAGKDASYVGRIRADETAEHGLALFVSNDNLRKGAALNAVQIAELVAAELKG"
     gene            complement(5011..5553)
                     /locus_tag="FNV64_RS22665"
                     /old_locus_tag="FNV64_23020"
     CDS             complement(5011..5553)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986799.1"
                     /locus_tag="FNV64_RS22665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23020"
                     /product="DUF1203 domain-containing protein"
                     /protein_id="WP_240362258.1"
                     /transl_table=11
                     /translation="MTHTTDATTDMTTYATTFATTYTARPIDPAVLKDLRTADDADRPM
                     VPFADEEGGAPLRCCLRRSEPGERIALVSYAPLRRWAAGTGVDPGAYDEQGPVFIHADD
                     CPGPDLRGHPFPGAHRTVRRYSAEGHILGGRLVENPEAFDDAFDEAFADAFADPEVALV
                     HVRAVEYGCFLYEVRRA"
     gene            5665..8244
                     /gene="pepN"
                     /locus_tag="FNV64_RS22670"
                     /old_locus_tag="FNV64_23025"
     CDS             5665..8244
                     /EC_number="3.4.11.2"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pepN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672746.1"
                     /locus_tag="FNV64_RS22670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23025"
                     /product="aminopeptidase N"
                     /protein_id="WP_143601650.1"
                     /transl_table=11
                     /translation="MPGTNLTREEAQQRAKLLTVDSYEIDLDLSGAQEGGTYRSVTTVR
                     FDVEENGSETFIDLVAPAVHEVTLNGDPLDPAEVFTDSRIALPGLLEGRNVLRVVADCA
                     YTNTGEGLHRFVDPVDQQAYLYTQFEVPDARRVFASFEQPDLKATFQFTVKAPTGWTVI
                     SNSPTPEPKDDTWVFEPTPRISTYITALIVGPYHSVHSVYEKDGQSVPLGIYCRPSLAE
                     FLDSDAIFEVTRQGFEWFQEKFDYAYPFKKYDQLFVPEFNAGAMENAGAVTIRDQYVFR
                     SKVTDAAYEVRAATILHELAHMWFGDLVTMEWWNDLWLNESFATYAEAACQAYAPQSRW
                     PHSWTTFANSMKTWAYRQDQLPSTHPIMAEINDLDDVLVNFDGITYAKGASVLKQLVAY
                     VGMDEFFKGVQAYFKRHAYGNTRLSDLLGALEETSGRDLKTWSEKWLQTAGINILRPEL
                     ETDANGVITSFAIRQEAPALPEGAKGEPTLRPHRIAIGLYNLDDDSGRLVRDQRVELDV
                     DGELTAVPELVGKRRPAVFLLNDDDLSYAKVRLDEDSLAFVTEHLGDFESSLPRALCWA
                     SAWDMTRDGELATRDYLSLVLSGIGKESDIGVVQSLQRQVKLAIELYADPTAREALLTR
                     WTDATLAHLRAAEPGSDHQLAWARAFSATARTPEQLDLLEGLLEDRESIGGLAVDTELR
                     WAFVQRLAAVGRYDEAEIGAEAERDKTAAGERHAETARASRPTEEAKAEAWAAVVESDK
                     LPNAVQEAVIGGFAQTDQRELLAPYTDKYFSVVKDIWDARSHEIAQQIVVGLYPSVQVS
                     EETLAKTDAWLAAAEPTPALRRLISESRSGIERALKAQAADAAAASA"
     gene            complement(8344..9648)
                     /locus_tag="FNV64_RS22675"
                     /old_locus_tag="FNV64_23030"
     CDS             complement(8344..9648)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116434.1"
                     /locus_tag="FNV64_RS22675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23030"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_143613389.1"
                     /transl_table=11
                     /translation="MRGTPYPTLGELLRRARATVAARPGALRLRAVGTSRAGRPLWLLS
                     AGHGPRHILTVAGAHANEPVGGVTSLSLAERFAREPALLQESGCTWNFLLCLDPDGASL
                     AGRWLTGLPGEGLPGEGRPGEGLPGEGRAAAEASPTLRGYYRRFYRPAFAAQPEFPPVM
                     SDPRPVMPESEALVRLIDELRPVVQFSLHGVEVGGSFLQLTRAVPGAAAAYRRIAADLG
                     IPLEHRPFDGMGWLAESPGVLVLPDSGPTEERDPSGFTSQATWLYAMRHGTVSAVVEAP
                     FWSVAGVSDPRPVAEPRREVAEASEILLGRAKQLEAVVGELGPRAPETPEEIAHFTAAR
                     ELMDIGPGVVDTWNSAELATTVGNAVSLGVAARRIPLRAAAMMRQALGGAPALDTLVEA
                     WARELASTFDARWVPVTDQTELQIRTMLALARALV"
     gene            10001..11302
                     /locus_tag="FNV64_RS22680"
                     /old_locus_tag="FNV64_23035"
     CDS             10001..11302
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387620.1"
                     /locus_tag="FNV64_RS22680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23035"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_240363665.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 5.4e-22,
                     bitscore: 77.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.7e-40, bitscore: 138.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVDTLRRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWV
                     WTLVETMDGTREPAAVVGEVLRAHPELPDLTPEDARQAMADLLDAGFVEDAAAPVPVSE
                     RERLRYSRGVPLLRWMDLGPRTSPWDAQLRLRRARVLLVGVGGTGGYAAQGLVASGVGR
                     LHCVDPDVVELSNLNRQPLFRESDLGRPKVTAALATLRALNSDVTVTGERREIRHPADL
                     ARLIRTGAPEAPSEPKRAGTPQAPSEPTHAGTPEVPYSSRSSYDLLVLAADRPDDIRRW
                     ANRVCLTADLPWVDAGYRGPLVTAGVHVPGRGACWECLRAGEVARRELRLAPGQDDGVA
                     SPHLPWNPATAVTAGLSGGLLAHAALALLTGVPALDPGFRFGMNLMLPGDPVLQRFPRR
                     TDCPACGDRPDDGATGAGGATGPGGATGPAGERA"
     aSDomain        10019..10309
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FNV64_RS22680_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.40E-24"
                     /identifier="RREFam017.1"
                     /label="FNV64_RS22680"
                     /locus_tag="FNV64_RS22680"
                     /protein_end="103"
                     /protein_start="6"
                     /score="77.0"
                     /tool="antismash"
                     /translation="RRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWVWTLVET
                     MDGTREPAAVVGEVLRAHPELPDLTPEDARQAMADLLDAGFVEDAAAPVPVS"
     gene            11299..12459
                     /locus_tag="FNV64_RS22685"
                     /old_locus_tag="FNV64_23040"
     CDS             11299..12459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116436.1"
                     /locus_tag="FNV64_RS22685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23040"
                     /product="hypothetical protein"
                     /protein_id="WP_143655018.1"
                     /transl_table=11
                     /translation="MNHVRLHALDSRPDGDEWIVGRLATGRFVALPEVGKQALDLLGQG
                     LSTTEVEVQLRETTGDDIDVPDFVEALVDLGFVAEVDGREVASPPPPKPTLARIGPRHV
                     RWVLSPALPVLIALLITTTLLTRPPVPLGYRTLLWSPHGSAVIALGAGFGWTLLLLHEC
                     AHLMTARATGVPGRMRLGTRLQFLVMQTDISGIELAPRRHRLTAYLAGIATNLTVASLA
                     ALAAGATHGTPRRILAAVALLALLPLPFQLMVFMRTDLYFVLQDVTRCRDLYGDGVAYT
                     KYAARRALRRTTAPDPSLELPAHERRAVRAYSVVLVVGTTLCLAFLATVTLPADITLFA
                     RAVAHLGPGYSPAVRLDATAVVVALGGVHVLWARTWWRDRRGRRSS"
     gene            complement(12508..13284)
                     /locus_tag="FNV64_RS22690"
                     /old_locus_tag="FNV64_23045"
     CDS             complement(12508..13284)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063168.1"
                     /locus_tag="FNV64_RS22690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23045"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_097284748.1"
                     /transl_table=11
                     /translation="MLLTDKTAVIYGAGGSIGGAVARTFAREGAHVHLVGRTAATLDAV
                     AKDIEAEGGHAGTAVVDALDEAAVEAHIASLDAVDISFNLVTRGDVQGASLLDMSVDDF
                     VRPVVTGIRANVVTARAAARRMAERGSGVVLTLNSGSAHGSPMMGGTGPADAAIDTLVR
                     NLAMELGPRGVRAVGLWAAGVPETLTREKLAAVDSAMALDENALQGLLANLAGMRMTRR
                     NPTLPEIAATAAFLASDHAGGITGTFVNVTGGMFPG"
     gene            complement(13386..14687)
                     /locus_tag="FNV64_RS22695"
                     /old_locus_tag="FNV64_23050"
     CDS             complement(13386..14687)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063167.1"
                     /locus_tag="FNV64_RS22695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23050"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_225900304.1"
                     /transl_table=11
                     /translation="MYCSAACRQRAYRERRAAPSDTAQGLIEEVGRQVRELVPAPPAVF
                     YSGVSELAASVGRLRRIARTARDTAGPGTADPVTEEPVLDEPVMGEPGAVDLVTTGPVT
                     EVALAESDFAALVESYRRELRVHCYRMSGSYDDAEDLVQETFLRAWRARDGFAGRASVR
                     TWLYRIATNACLDFQRRTARRPQRYEPLPGMNHGGAEPPARVTWLQPYPDDDLPSTEEQ
                     PDALAVSRETLELVFLAAIQHLPPRQRAVLVLRDVLGLAAAETAAVLDMTVASVNSALQ
                     RARPTLRDHLPRRRAEWTAEADVREREILARYMAAAERLDLTEVATLLSEDITLTMPPN
                     PFWFVGREALVEFLSVSLDPASPMFLGHWRHLPARANGQLAAGGYVRRPGTTVYRAQVL
                     DVLRVEGDRIVEITSFEPHLFPAFGLPLRLPADR"
     gene            complement(14822..15775)
                     /locus_tag="FNV64_RS22700"
                     /old_locus_tag="FNV64_23055"
     CDS             complement(14822..15775)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003543.1"
                     /locus_tag="FNV64_RS22700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23055"
                     /product="EamA family transporter"
                     /protein_id="WP_225900305.1"
                     /transl_table=11
                     /translation="MAANANRPALIALTALAPISWGSTYAVTTEFLPADRPLFTGVMRA
                     LPAGLLLLALARVLPRGAWWGKAALLGALNIGAFFPLLFLSAYRLPGGMAAVVGSVGPL
                     FVAGLAALLLGDRPTLRTLLTGIAAALGVSLVVLQAAGALDAVGVLAALAATASMSTGT
                     VLTKRWGRPDGVGPLALTAWQLTAGGLLIVPVALLVEGAPPALDGRAVGGYLYLALANT
                     AVAYWLWFRGIGRLSATQVTFLGPLSPLTAAVIGWAALGQSLTPVQVAGMVLAFGATVL
                     GQVGPRGGRPAPVGGFAGGGCGAGGAAITSRRPRVT"
     misc_feature    15809..15825
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            15902..16399
                     /locus_tag="FNV64_RS22705"
                     /old_locus_tag="FNV64_23060"
     CDS             15902..16399
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003542.1"
                     /locus_tag="FNV64_RS22705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23060"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_060900742.1"
                     /transl_table=11
                     /translation="MKTPQDPVDAIIEQWATVRPDLDTAAMEVFGRVFRLARTMGDRME
                     KAYAPYGISRGEFDVLATLRRSDAPYTLSPRQLSATLMLTTGGMTGRLDKLERAGLLRR
                     SPDPHDRRGLQVTLTDKGLRLIDEAVGAGLAVQTEALAHLDEERAGQLAALLRELLMGA
                     GA"
     gene            complement(16436..17296)
                     /locus_tag="FNV64_RS55280"
     CDS             complement(16436..17296)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS55280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_240363401.1"
                     /transl_table=11
                     /translation="MYLHVKQKIVTLATALCLTVGAGTAAATGPAPKREPEGIFLGAAL
                     LAWLARAGASLDVDQYVYYDCDDQRGDGDPGQWRHHHPRTVEDGSWTSTRGLRRKPTLG
                     STLEPRWFRVVKRKLMGMTTTDYVISASLILLVIPQIRGVRQTLHHTLLPLAAVAAAAA
                     YYLKSFPTQGHDLGLDIAGVVAGAVLGVACGAATRLSRASDGIAFARAGALAALLWIVG
                     MASRAGFEYWATHGGSGSLARFSQDNLITGSAAWTAALLLMALAQVLGRLTVIRVRSSR
                     VAAAG"
     misc_feature    complement(17286..17299)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.47"
                     /tool="antismash"
     misc_feature    17290..17303
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.5"
                     /tool="antismash"
     misc_feature    17390..17405
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    17391..17404
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    17512..17527
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(17545..19050)
                     /locus_tag="FNV64_RS22715"
                     /old_locus_tag="FNV64_23070"
     CDS             complement(17545..19050)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136111.1"
                     /locus_tag="FNV64_RS22715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23070"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_240363402.1"
                     /transl_table=11
                     /translation="MNGKTNGKVNGTNGSRHVIVVGSGPTGLLLAGDLAAAGVPVTLVE
                     KRPHGISNLSRAFVLHARTLEQLDARGLADELESHGRTVDRIRLFGGLSVALDTLPSRF
                     NHLLVIPQYEVERALERRAVEAGVRFVYETEVTGLRQDAAGVTLEVRGADGAAGEMAAA
                     YVVGADGMRSAVREAVGLPFPGKSVIRSVVLADVLLAEEPESILTANAVGDAFAFMVPF
                     GDGYYRVIGWHRGRDVPDSAPLELDEVKEIVRLSLGHDYGMHDARWMSRFHSDERQAPA
                     YRVGRVFLAGDAAHVHTPAGGQGMNTGLQDAANLSWKLALVVNGHADTDLLDTYQAERH
                     PVGKAVLRSSGGIVRLAMAKYPWTLALRSVLTTVLNAVGPVRRKAAGQITGIGFAYRAP
                     RGSHALVGTRAPDVTLKGGRLYEALRGGRFVLVAPTAAVRAYGLDDLKGRKDRLAVESW
                     ASDRRTTLLVRPDGYVAWAAESPDATAVERALAAALGEDPSSN"
     misc_feature    19094..19107
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            19164..19757
                     /locus_tag="FNV64_RS22720"
                     /old_locus_tag="FNV64_23075"
     CDS             19164..19757
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127872.1"
                     /locus_tag="FNV64_RS22720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23075"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_097284752.1"
                     /transl_table=11
                     /translation="MPDKELPAPAASPAARRSDTTRTAILTAARERFAADGYERATIRS
                     IAKDARIDPSMVMRYYGSKEGLFAAVLDVDLRLPDPVGLDPHEVGRALVGHFLDLWEEN
                     EVLTVLLRVGVTNPDGAARMQGIFRDQLMPVALRVCPDPEQAPARAALTASQVLGMAMA
                     RYVLRFPPAVALPREEVVAWLAPTVQRYLTAPHP"
     gene            complement(19894..20133)
                     /locus_tag="FNV64_RS22725"
                     /old_locus_tag="FNV64_23080"
     CDS             complement(19894..20133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643174.1"
                     /locus_tag="FNV64_RS22725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_23080"
                     /product="hypothetical protein"
                     /protein_id="WP_054231770.1"
                     /transl_table=11
                     /translation="MDKKNALRAGALASGTTLMMLLMSSPALALTRDDGDDPGKGLSVI
                     ETLGLYVVTPIVLFLVIAGLVMVLDKSDKQPKRT"
     misc_feature    complement(21034..21051)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
ORIGIN
        1 gatcggtcac ttcgggaccg acgacccggc caccgacgtc gtcgagagcc agccgttcgt
       61 cgtgcagatc cgcaaggacg tgccgatgga cccgtacggc gggtcctggg tcggcaagaa
      121 ggccgacttc gtcaacatcg gtctgatcgc gagcgagcac ggcacgcacg tcgccggcat
      181 cacctccgcg aacggcctgt tcggcggcaa gatgaacggc gccgcccccg gcgcgaagat
      241 cgtctcgtcg cgcgcctgcg tgttcggccc gagctgcacc aacgtcgcgc tcaccgaggg
      301 catgatcgac ctcgtcgtca accacggcgt cgacatcgtg aacatgtcca tcggcggcct
      361 gcccgcgctg aacgacggca acaacgcgcg ctccgagctc tacacgcgtc tcatcgacac
      421 ctacggtgtc cagctggtga tctccgcggg caactccggc cccggcgcca acaccatcgg
      481 cgaccccggc ctggccgaca aggtcatctc ggtcggcgcg tccatctcca aggacacctg
      541 ggccgccaac tacggctccg tcgtggagaa gaagtacgcg atgatgccgt tctcctcgcg
      601 cggtccgcgt gaggacggcg gcttcacgcc gacgctgacc gcgcccggcg ccgcgatcaa
      661 caccacgcag acctggctgc cgggctcccc ggtcgcccag gccggctact ccctgccggc
      721 cggctactcg atgctccagg gcacctcgat ggcctccccg caggccgccg gcgcgtccgc
      781 gctgctgctg agcgccgcca agcagagggg catcgacctg acgcccgcca agctgcgcac
      841 ggccctcacc tcgaccgccg accacatcaa gggtgtgcag gcgtacgagg agggcgcggg
      901 cctcatcaac atcgtggacg cgtggaagtc gatcaaggac gacgtgaccg cccacgacta
      961 caccgtcaag gcccccgtcg acaccgcgat cgactacgcc ctgaagaccc cgggcttcgg
     1021 caccggcctc tacgaccgcg agggcggcct caaggtcggc gtgaagaaga cgtacgacat
     1081 caccatcacg cgtacgtccg gcccggacaa ggcgatccgc cacgagctgc acttcgagaa
     1141 caacgccggt gacaccttcc ggatcgtcgg ctccgacgag gtcaagctcg aactgaacaa
     1201 gccggtcacc gtcaaggtcg ccgcgaaggc ctcctcggcc ggcatcaaga gcgcgatcct
     1261 cgaggtcgac gacccgcgga ccgagggcgt ggacaagcag atcctgacga cggtcgtggt
     1321 ctccactcca ctcaagtaca gctactccgc gtcgagttcg gtgcagcgca acagcacgcg
     1381 gtcgtacttc ctgaccgtgc ccgagggcgc gaaggcgctg gaggtcgcga tcggcgggct
     1441 gaaggacctg agccagaccc ggttcatctc catccacccc tacggtgtcc cggtcgagga
     1501 caccggcacg ccgtactgct acagcaacta cccgaacacc aacggctgca agcccgacgt
     1561 gcgtgcgtac gcggacccgc agcccggtgt ctgggaggtc gaggtcgagg cgcgccgtac
     1621 ctcgccgctg ctcgacaacc cgtacaagct ggaggccacc gtgctcggcg cggccttcga
     1681 cccggccgtg gtgacggtcc ccgaggcgaa ggtcggcacg ccggtcaccg cctcctggaa
     1741 ggtgacgaac ggtttcgcgg cgctcgacgg caccctgaag ggcggcccgc tcggctcctc
     1801 gaagacggcc cggccgacca tcgcgggcgg cgccacccag accagcacgg tcgaggtgcc
     1861 ggccggcgcc gcgtcgctcg acgtcgccat cggcaacgtc tcggacacgg ccgccgacct
     1921 ggacctgacg gtgtacgact ccgcgggcaa gcaggtcgcg cagtccgcgg acggcgactc
     1981 ggaggaggcg gtctccatcc ccaaccccgc cgccgggacg tacaccatcg aggtcgtggg
     2041 ctactcggtc ccgtcgggct cgaccgcgta cgactaccgt gacgtgttct tctcctccgc
     2101 gctcggctcg gtcaaggtcg acgagtcggc gccggtgaag ctcgccacgg gcggtacggc
     2161 gacggtgtcc ggcgaggtca ccgcggccgc accggccccc gagggacgcg agttcttcgg
     2221 ccgggtccag ctggtgaacg cccgcggcac ggccgccggc ctcggcagcg tgaagatcga
     2281 gaaggtcacg ccgtagcaac cggctgacat acgaggggcg ggcgtccgga aacgggcgcc
     2341 cgcccttcat cacgggcacg tgccttcatc acgggcacgt gccttcatca cgggcacgtg
     2401 agggtgcggg acgcgggcag cgccttcacg atccacgccc gttcgtcggc gatggccttg
     2461 tcccccgtgg tccagccggt cggtgtcgcc gggtcgccct ggacggcgac gagtacccgc
     2521 tcgccctcac gcggccgggg agccacctcc tcgtccagga cgaggacgac ctcggccctc
     2581 cccttctcgg gcttgtagta gcggtccacg tggagggtga tccggttctc cgtggtgccg
     2641 gggagcggct cgacgtgggc gaccgtgccc tccgccacga gccgggcgca ggccagatag
     2701 ccgggggcgc tcagcgaggc accgccgccc gcggtcccgc tgtcggccgc cttggccccg
     2761 ctggaatccg acgcgcctgc cccgttgtgc gcgaggatcc agcccatgcc gacgaccatc
     2821 gcggccacgg tggccgcgac gagggtgccc aggaccaggg ctaggggacg gcgcccgcgg
     2881 ttcctggggg cgccttcggg gcggcgggtg cgcttcctgg gggcccgtac cgggaccggc
     2941 ttcgcttcct gcgcacggtc cgccagcgcg tccccgatga ccgccaactg ctcccgcagc
     3001 agcgccacgt cggccaccgc cgaccggtgc tcggccagga actccgggtc gtcgccggcc
     3061 ccttcgggca gagcctcgtc agtgatcgcg gccaacagcg cgtccactcc ctcatactcg
     3121 gccacgtcac accacctcgt cctcgtgcag gcgggcgcgc agggcgcgga ccgccgagtg
     3181 cagcctgctc ttgaccgtgc cctccgggat gccgagctcc tcggcgatcc cgcgcacgga
     3241 cagatcggcg tagaaacgca ggacgaggac ctggcgctgg gcgtcgggca gctcgtccaa
     3301 accccgcgcc acggcgagcg agagcacgct ggagtcctcg tcacgggcgt ccgcgggctg
     3361 ccgcagcgag gccagccgct cgccgagccg ctcctggcgt cgcttggccc ggtgccagtc
     3421 catcgccagg ttcgaggcga cgaccgccgc ccacgcggac acgtcacgcg gcgcctcgtc
     3481 ccccttcgcc gcgcgttcca gcaaccgcag gcggacctgc tgcaccccgt ccggcaggtc
     3541 cgcctgcggt acgccaccga gcgcgagcac cgcccgcacc cggcgttcct gggccgcgtc
     3601 caggggatcg tccgccccct ggacccggcg tgcctttctg cgcagcactc cgcccctccc
     3661 ctcccgcgtt tcctctacga cgccggtgcg ggccaaaacg ttcggccgca cgcgaaggag
     3721 tcgtacgtca caccgggccg gggccggtga ggatgcccac gccgtacggc ttgcggttcc
     3781 cggcggccga cggacggttt tctttcggat gccgcaggaa tgccgaaggg cggacgtgtc
     3841 ccattccgcg ggcggcacgg gcaaaggatt ggacacgcgg ggacgggtca gacgcatgat
     3901 ggaagcgctg gaccacgtaa aacgcacgct aagggagtcg ccgtgagggt cggaatcgtc
     3961 ggagccaccg gtcaggtcgg cacagtcatg cgcaggatcc tcgtcgagcg gaagttcccg
     4021 gtcgaggagc tgcggctgtt cgcctccgcg cgttcggccg gaaccgtgct cgacggtgtg
     4081 acggtggagg acgcggcgac ggcggactac tccggcctgg acatcgtgct gttctccgcg
     4141 ggcggcgcga cctccaaggc actggccgag aaggtcgccg cgcagggcgc ggtcgtgatc
     4201 gacaactcct cggcgtggcg caaggacccg caggtgcccc tggtggtctc cgaggtgaac
     4261 ccgcacgcga tcgccgaccg ccccaagggc atcatcgcca acccgaactg cacgacgatg
     4321 gccgcgatgc cggtcctgaa gccgctgcac gaggaggcgg ggctcgaggc gctggtcgtc
     4381 gcgacgtacc aggcggtgtc cggttccggc ctcgcgggcg tggccgagct gcacggccag
     4441 gtactgaagg tcgccgcgga cgccgacaag ctgacccacg acggcggcgc ggtcgacttc
     4501 cccgagccgg gggtctacaa gcgccccatc gccttcaacg tgctcccgct cgcggggtcg
     4561 ctcgtcgacg acggtctgca cgagacggac gaggagcaga agctccgcaa cgagtcccgc
     4621 aagatcctgg agatccccgc cctcaaggtc tccggcacct gtgtccgcgt ccccgtgttc
     4681 agcggccact ccctccaggt gaacgcccgc ttcgcgcgtc cgctgagcgt ggagcgcgcg
     4741 accgagttgc tggccggcgc cccgggcgtc accctctccg agatcccgaa cccgctcgag
     4801 gccgccggca aggacgcgtc ctacgtgggc cgcatccgcg ccgacgagac ggccgagcac
     4861 ggcctcgccc tcttcgtctc caacgacaac ctccgcaagg gcgccgcgct gaacgcggtc
     4921 cagatcgcgg agctggtggc ggcggagctc aagggctgac gcccgcgcca catgccccgg
     4981 gggcggtcac cgcacggtga ccgccccttc tcacgcccgc cgcacctcgt agaggaagca
     5041 cccgtactcc acggcccgta cgtggacgag cgccacctcc gggtcggcga aggcatccgc
     5101 gaaggcctcg tcgaaggcgt cgtcgaaggc ctcggggttc tcgaccagac ggccgcccag
     5161 gatgtggccc tcggcggagt agcggcggac cgtgcggtga gcgcccggga aggggtggcc
     5221 gcgcaggtcg gggcccgggc agtcgtcggc gtggatgaag accgggccct gttcgtcgta
     5281 cgcgcccggg tcgacgcccg tcccggcggc ccagcggcgc agcggcgcgt aggagacgag
     5341 ggcgatccgc tcccccggtt cactgcgccg cagacagcag cgcagcggcg cgccgccctc
     5401 ctcgtccgcg aagggaacca tcggacggtc cgcatcgtca gctgtgcgga gatccttcag
     5461 gaccgccggg tcgatgggac gtgccgtgta cgtcgtcgcg aatgtcgtcg cgtatgtcgt
     5521 catgtccgtc gtcgcgtccg tcgtgtgcgt catgtattca ggctcgcgcc cgcgcgtgcc
     5581 gggcaccggc gggaaacgga catcgcatcc gtgcaggtcc catggaagga tggcgcaacc
     5641 gtcacataac gaggagatga ccgcgtgcct ggcacaaacc tgacccgcga agaggcgcag
     5701 cagcgcgcga agctgctcac cgttgactcg tacgagatcg atctcgacct ctcgggcgcg
     5761 caggagggcg gcacctaccg gtccgttacc acggtgcgct tcgacgtcga ggagaacggc
     5821 tcggagacct tcatcgacct ggtggctccc gccgttcacg aggtgaccct gaacggggac
     5881 cccctcgacc cggccgaggt cttcacggac tcgcggatcg cgcttcccgg gctcctggag
     5941 ggccgcaacg tcctgcgtgt cgtggccgac tgcgcgtaca ccaacaccgg tgagggcctg
     6001 caccgcttcg tcgaccccgt cgaccagcag gcctacctct acacccagtt cgaggtcccg
     6061 gacgcgcgcc gggtgttcgc gtccttcgag cagcccgacc tgaaggccac cttccagttc
     6121 accgtgaagg cgccgacggg ctggaccgtg atctccaact ccccgacgcc cgagcccaag
     6181 gacgacacct gggtcttcga gccgacgccg cggatctcca cgtacatcac cgcgctgatc
     6241 gtcgggccgt accactccgt gcacagcgtg tacgagaagg acggacagag cgtgccgctc
     6301 ggcatctact gtcggccctc gctcgccgag ttcctcgact cggacgcgat cttcgaggtc
     6361 acccggcagg gcttcgagtg gttccaggag aagttcgact acgcctaccc gttcaagaag
     6421 tacgaccagc tcttcgtgcc ggagttcaac gccggcgcga tggagaacgc gggcgcggtg
     6481 accatccgcg accagtacgt gttccggtcc aaggtgaccg acgccgcgta cgaggtgcgg
     6541 gccgccacga tcctgcacga gctggcccac atgtggttcg gcgacctggt caccatggag
     6601 tggtggaacg acctgtggct gaacgagtcg ttcgccacct acgccgaggc ggcctgccag
     6661 gcctatgccc cccagtcgcg ctggccgcac tcctggacga ccttcgccaa ctccatgaag
     6721 acgtgggcgt accggcagga ccagctgccc tccacccacc cgatcatggc cgagatcaac
     6781 gacctggacg acgtcctcgt caacttcgac ggcatcactt acgcgaaggg ggcgagcgtc
     6841 ttgaagcagc tcgtcgccta cgtcggcatg gacgagttct tcaagggcgt gcaggcgtac
     6901 ttcaagcggc acgcctacgg caacacgcgc ctcagcgatc tgctgggcgc cctggaggag
     6961 acctccgggc gtgacctgaa gacctggtcg gagaagtggc tccagaccgc cggcatcaac
     7021 atcctgcggc cggagctcga gacggacgcg aacggggtca tcacctcctt cgcgatccgt
     7081 caggaggctc cggcgctccc ggagggtgcc aagggtgagc cgaccctgcg tccgcaccgc
     7141 atcgcgatcg gcctctacaa cctcgacgac gacagcggca ggctggtgcg cgaccagcgc
     7201 gtcgagctgg acgtcgacgg cgagctgacg gccgtaccgg agctggtcgg caagcgccgc
     7261 ccggcggtct tcctgctcaa cgacgacgac ctgtcgtacg ccaaggtccg cctcgacgag
     7321 gactcgctcg ccttcgtcac cgagcacctc ggcgacttcg agtcgtccct gccccgtgcc
     7381 ctgtgctggg cctcggcctg ggacatgacc cgcgacggtg agctcgccac ccgcgactac
     7441 ctgtccctgg tcctgtcggg catcggcaag gagtccgaca tcggtgtcgt gcagtcgctg
     7501 cagcgccagg tgaagctggc gatcgagctg tacgccgacc cgacggcccg cgaggcgctg
     7561 ctgacccgct ggacggacgc gacgctcgcg cacctgcgcg ccgccgagcc cggcagcgac
     7621 caccagctcg cctgggcgcg tgccttctcg gcgaccgccc gtacgccgga gcagctggac
     7681 ctcctggagg gcctgctgga ggaccgggag agcatcgggg gcctcgccgt cgacaccgag
     7741 ctgcgctggg cgttcgtcca gcggctcgcg gcggtcgggc gctacgacga ggcggagatc
     7801 ggcgccgagg cggagcgcga caagacggcg gccggtgagc ggcacgcgga gacggcccgg
     7861 gcctcgcgtc ccaccgagga ggcgaaggcg gaggcctggg ccgcggtggt cgagtccgac
     7921 aagctcccga acgccgtaca ggaagcggtg atcggcggct tcgcgcagac cgaccagcgc
     7981 gagctgctcg ccccgtacac ggacaagtac ttctccgtgg tgaaggacat ctgggacgcc
     8041 cgttcgcacg agatcgccca gcagatcgtg gtcggtctct acccgtccgt ccaggtctcc
     8101 gaggagaccc tcgccaagac ggacgcgtgg ctggccgcgg ccgagcccac cccggccctg
     8161 cggcgcctga tctcggagtc ccgctccggg atcgagcgcg cgctgaaggc ccaggcggcg
     8221 gacgcggcgg cggcttccgc gtagtcggtc gtacgtgaat gggggctccc ggcgtcgtgc
     8281 cgggagcccc ctttcgcatg agtgcgcgtg tgggcgtgtg tgggcgtgtg tgggcgcccg
     8341 gggtcacacc agggcgcggg cgagtgcgag catcgtgcgg atctggagct cggtctggtc
     8401 ggtcacgggg acccagcggg cgtcgaaggt gctcgccagc tcacgtgccc aggcctccac
     8461 gagggtgtcc agcgcggggg cgccgcccag ggcctgccgc atcatggccg ccgcgcgcag
     8521 cgggatgcgc cgggcggcga cgccgagcga gacggcgttg cccacggtgg tggcgagttc
     8581 ggcggagttc caggtgtcca cgactccggg gccgatgtcc atgagctcac gggcggcggt
     8641 gaagtgggcg atctcctcgg gggtctcagg tgccctgggc cccagctccc ccaccaccgc
     8701 ctccagttgt ttggcccggc cgagcaggat ctcgctcgcc tccgcgacct cgcgccgggg
     8761 ctcggcgacg ggccgaggat cgctgacgcc ggccacgctc cagaagggcg cctcgacgac
     8821 cgccgacacg gttccgtgcc gcatcgcgta cagccaggtc gcctgtgagg tgaagccgga
     8881 cgggtcccgt tcctcggtgg ggccgctgtc cggcaggacg agcacgcccg ggctctcggc
     8941 cagccatccc atgccgtcga acggccggtg ttccaggggg atgccgaggt ccgccgcgat
     9001 ccggcggtag gcggccgccg cccccggcac cgcgcgagtc aactgcagaa aggatccgcc
     9061 cacttcgacg ccgtggagcg agaactgcac gaccgggcgc agttcgtcga tgagccgcac
     9121 cagcgcctcg gactccggca tcaccggacg cgggtcactc atgacgggcg gaaactcggg
     9181 ctgcgcggcg aaggcgggcc ggtagaagcg ccggtagtag ccccggaggg tcggcgaggc
     9241 ctcggccgcc gcccgaccct cgccgggcag cccctcgccg ggccgcccct cgccagggag
     9301 cccctcgcca ggcagcccgg tcagccatcg cccggcgagg ctcgcgccgt cggggtcgag
     9361 gcagagcagg aagttccagg tgcagccgga ctcctggagc agcgcgggct cccgcgcgaa
     9421 cctctcggcc agggagagcg aggtgacccc gcccaccggt tcgttggcgt gcgcgccggc
     9481 gaccgtgagg atgtgccggg ggccgtgtcc ggcggacagc agccacagcg gccggccggc
     9541 acgcgaggtc ccgacggcac gcaaccgcag tgcaccgggc cgtgccgcca ccgtcgcgcg
     9601 agcgcgtcgc agcagctcac cgagggtggg atacggggtt ccccgcatgc cgggctccgg
     9661 tcaggtgccg ttcgcgttgc tgtccccggt ggtctccttc ttgtccagcg gacggatcac
     9721 gatcttggcg gccatgtggc cccctctctg tgtgggctct gcggtggccg agttcctgtc
     9781 cggcgaaacg gatcagccgc cgttgcctcc gctgctgtcg cccgtggtct ccttcttgtc
     9841 caacgggcgg atcacaatct tggtgggcac cccaactcct ctcgtcagta gggacgttga
     9901 gcgttgcggg cgcgatcgcc gaccgcgtct tgtcaaggct cgactcgggg gaccagagtg
     9961 tcaaggcatg tacctgtaac gggaaggggt cctggtgacg gtgccggtcg acacgctccg
    10021 caggccccgg atcaagcccg agcaccggcc gtaccgcacg atcgacggca acgtccgcat
    10081 cggcagcgtc atccacggca tcggcgccga gatcgaggac ccgcagggct gggtctggac
    10141 gctggtcgag acgatggacg gaacgcggga gccggcggcg gtggtcggcg aggtgctgag
    10201 ggcgcatccc gaacttcccg acctcacgcc cgaggacgcc cggcaggcga tggcggacct
    10261 gctcgacgcc gggttcgtgg aggacgcggc ggcgcccgtg ccggtgtccg agcgggaacg
    10321 gctgcgctac agccgggggg tgccgctgct gcgctggatg gacctcggcc cccggacgag
    10381 tccctgggac gcccagctcc ggctgcgccg ggcccgggtg ctgctggtcg gcgtcggcgg
    10441 cacgggcggg tacgccgcac agggcctggt cgcctccggg gtcggccgtc tgcactgcgt
    10501 ggacccggac gtggtggagc tgtccaacct caaccgccag cccctcttcc gcgagtccga
    10561 cctcggccgc ccgaaggtga cggccgcgct cgccaccctg cgggcgctga actcggacgt
    10621 gacggtgacc ggggaacgcc gggagatacg acacccggcg gacctggcga ggctgatacg
    10681 gaccggggca cccgaagccc cgagcgaacc gaaacgggcc gggacgcccc aagccccgag
    10741 cgaaccgaca cacgccggga cacccgaagt cccgtactcg tcgcggagct cgtacgacct
    10801 tctcgtcctc gccgccgacc gtcccgacga catccgccgc tgggcgaacc gtgtctgtct
    10861 gaccgcggac ctgccctggg tcgacgccgg ctaccgcggc cccctggtga cggccggggt
    10921 ccacgtaccc ggccggggtg cctgctggga gtgtctgcgg gccggtgagg tggcccgccg
    10981 cgagctgcgc ctggcgcccg gccaggacga cggggtcgcc tccccgcacc tgccgtggaa
    11041 ccccgcgacc gcggtcaccg cgggcctgtc cggcggactg ctcgcccacg cggccctggc
    11101 cctgctgacc ggcgtcccgg cgctcgaccc cggcttccgt ttcgggatga acctgatgct
    11161 gccgggcgac ccggtgctgc agagattccc gcggcgaacc gactgcccgg cgtgcggcga
    11221 cagacccgac gacggagcca ccggcgcggg cggagcgacc ggaccgggcg gagcgaccgg
    11281 accggctggg gagcgcgcgt gaaccacgtg cgcctgcacg ccctcgactc ccgtcccgac
    11341 ggcgacgagt ggatcgtcgg ccggctggcg acgggccggt tcgtcgcgct gcccgaggtc
    11401 ggcaagcagg cgctggacct gctcgggcag gggctgagca ccaccgaggt cgaggtgcag
    11461 ctgcgggaga ccaccggcga cgacatcgac gtacccgact tcgtcgaggc gctggtggac
    11521 ctcgggttcg tcgccgaggt ggacggacgg gaagtggcct cgccgccccc gccgaagccg
    11581 acgctcgccc ggatcggtcc ccgccatgtg cgctgggtcc tcagcccggc cctgcccgtc
    11641 ctcatcgccc tgctgatcac caccaccctg ctcacccgcc cacccgttcc cctcggctac
    11701 cgcaccctcc tctggagccc gcacggcagc gcggtgatcg cgctcggcgc gggcttcggc
    11761 tggacgctcc tgctgctcca cgagtgcgcg cacctgatga ccgcccgggc gaccggcgtg
    11821 cccggccgga tgcgtctcgg cacgcgcctg cagttcctgg tcatgcagac ggacatcagc
    11881 ggcatcgaac tcgctccgcg ccgccatcgg ttgaccgcct acctcgccgg gatcgccacc
    11941 aacctcaccg tcgcctccct ggccgccctc gccgcgggcg ccacgcacgg caccccccgc
    12001 cggatcctgg ccgccgtcgc cctgctcgcc ctgctccccc tccccttcca gctcatggtc
    12061 ttcatgcgca cggacctgta cttcgtgctc caggacgtga cgcgctgccg tgatctgtac
    12121 ggggacgggg tggcgtacac gaaatacgcg gcacggcggg cgctgcgccg taccaccgcc
    12181 ccggacccca gcctcgaact ccccgcccac gaacggcggg cggtgcgcgc gtacagcgtg
    12241 gtgctcgtcg tcggcaccac gctgtgtctc gcgttcctcg cgaccgtcac cctgcccgcg
    12301 gacatcacgc tgttcgcccg cgcggtggcg cacctgggcc ccggctactc ccccgccgtg
    12361 cgcctcgacg cgacggccgt cgtggtcgcg ctcggcgggg tgcatgtgct gtgggcccgc
    12421 acgtggtggc gcgaccgccg cggccgtcgg tcctcgtagc cggtcctccc agccggccgt
    12481 cccagccggc cgtcccaacc ggtcgtccta gcccgggaac atcccgccgg tgacgttgac
    12541 gaacgtgccg gtgatgccgc ccgcgtggtc ggaggcgagg aaggcggcgg tcgcggcgat
    12601 ctcggggagg gtgggattgc ggcgggtcat gcgcattccg gccaggttcg cgagcaggcc
    12661 ctggagggcg ttctcgtcga gggccatggc gctgtcgacc gcggcgagct tctcgcgggt
    12721 cagcgtctcg ggcacgccgg ccgcccacag acccacggcc cgcaccccgc gcggacccag
    12781 ttccatcgcc aggttgcgca ccagcgtgtc gatcgccgcg tcggccgggc ccgttccgcc
    12841 catcatcgga ctgccgtgcg ccgaaccgct gttgagcgtg aggaccacgc cggagccccg
    12901 ctcggccata cggcgggcgg cggcgcgggc ggtgacgacg ttggcgcgga taccggtgac
    12961 gaccggacgt acgaagtcgt cgacggacat gtcgagcagc gaggcaccct gcacatcacc
    13021 ccgggtgacg aggttgaagg agatgtcgac ggcgtccagc gaagcgatgt gcgcctcgac
    13081 cgccgcctcg tcgagcgcgt cgacgaccgc cgtcccggcg tggccgccct ccgcctcgat
    13141 gtccttggcc accgcgtcga gcgtcgccgc cgtacgcccc acgaggtgca cgtgggcacc
    13201 ctcgcgggcg aaggtacggg cgacggctcc gccgatggat ccgccggcgc cgtagatgac
    13261 cgcggtcttg tcggtgagca gcatggtgaa cctccgtgag gtgggttgtc ggaacggccc
    13321 gtatgaatcg gccggaccag tcggccgtac gagtcggtca tgcagacgtt cgcgccgtct
    13381 ctcactcatc ggtcggcggg cagccgcagc ggcagtccga acgccgggaa gagatgcggc
    13441 tcgaaggagg tgatctccac gatccgatcg ccctcgacac ggaggacgtc gaggacctgc
    13501 gcgcggtaga cggtcgtacc cgggcgccgg acgtaccccc cggccgcgag ctgcccgttg
    13561 gcgcgggcgg gcaggtggcg ccagtggccg aggaacatcg gggaggccgg gtcgaggctg
    13621 acggacagga actcgacgag cgcctcgcgg ccgacgaacc agaacgggtt cggcggcatg
    13681 gtgagcgtga tgtcctcgct gagcagggtg gcgacctcgg tgaggtcgag gcgttcggcg
    13741 gcggccatgt aacgcgccag gatctcgcgc tcacggacgt ccgcctccgc ggtccactcg
    13801 gcgcggcggc ggggcaggtg gtcgcgcagg gtgggtcggg cccgttgcag cgcgctgttg
    13861 accgaggcga cggtcatgtc cagtaccgcg gcggtctccg cggcggccag ccccaggacg
    13921 tcgcgcagga cgaggacggc gcgctggcgg ggcggcagat gctggatcgc ggcgaggaag
    13981 acgagctcca gggtctcccg ggagaccgcg agcgcgtcgg gctgctcttc ggtcgagggc
    14041 aggtcgtcgt cggggtaggg ctggagccag gtgacgcggg ccgggggctc ggcgccgccg
    14101 tggttcatcc cgggcagcgg ctcgtaccgc tgcgggcggc gcgccgtgcg ccgctggaag
    14161 tccaggcagg cgttggtggc gatccggtac agccacgtcc gtacgctcgc ccgccccgcg
    14221 aacccgtccc gggcccgcca ggcccgcagg aacgtctcct gcacgaggtc ctcggcatcg
    14281 tcgtacgagc ccgacatccg gtagcagtgc acgcgcagtt cgcgccggta ggactcgacg
    14341 agcgcggcga agtcgctctc cgcgagggcc acttccgtaa cggggccggt cgtgacgaga
    14401 tccaccgcgc cgggctcgcc catgacgggc tcgtccaaga cgggctcctc cgtcacgggg
    14461 tccgccgtac cgggacctgc cgtgtcgcgg gccgtccggg cgatgcgccg cagccgtccc
    14521 acggaggcgg ccagctcgct caccccggag tagaagacgg cgggcggcgc cgggaccagc
    14581 tcacggacct gccgcccgac ctcctcgatg agcccctggg cggtgtccga gggcgccgcc
    14641 cgccgctccc ggtacgccct ctgccgacag gcggccgagc agtacacgga actccgcccc
    14701 ttgcgcccgg tccgccccgc cagcggcttc ccgcacccag gacacacacc gtcgaccaca
    14761 ggaacctcca ggaatcgggg aatcggggga gaggggaatc ggggcatggg gaatcgggga
    14821 attacgtcac gcgcggacga cgtgacgtta tcgccgctcc cccagccccg cagccacctc
    14881 ccgcaaagcc tccgacggga gccggccgcc cgccacgcgg cccgacctgg ccgagcaccg
    14941 tcgccccgaa cgccagtacc atccccgcca cctgcaccgg cgtcagcgac tgccccagcg
    15001 ccgcccagcc gatgacggcc gcggtcagcg gtgacagcgg gccgaggaag gtgacctggg
    15061 tggcgctgag ccggccgatg ccccggaacc agagccagta cgccaccgcc gtgttcgcca
    15121 gcgcgaggta caggtatccg ccgaccgccc ggccgtccag cgcgggcggc gcgccctcga
    15181 ccaggagggc gaccgggacg atcagcagcc cgcccgccgt caactgccag gcggtgagcg
    15241 ccaacggacc gaccccgtcc ggccggcccc accgcttggt gagcaccgtg ccggtggaca
    15301 tcgacgcggt cgcggcgagc gccgcgagga ccccgaccgc gtccagcgcg cccgccgcct
    15361 gcagcacgac gaggctgaca ccgagggccg cggcgatacc ggtgaggagc gtccgcaggg
    15421 tcgggcggtc accgagcagc agcgccgcga ggcccgcgac gaacagcggc ccgaccgagc
    15481 cgacgaccgc cgccatgccg ccgggcagcc gatacgcgga gaggaacagc agtggaaaga
    15541 aggcgccgat gttcagcgcg cccagcagcg ccgccttccc ccaccaggcg ccgcgcggca
    15601 gcacccgggc cagcgcgagg agcagcagcc cggcgggcag ggcgcgcatc accccggtga
    15661 acagggggcg gtcggcgggg aggaactccg tggtgacggc gtaggtgctg ccccaggaga
    15721 tgggggccag cgcggtcagg gctatgaggg cgggacggtt cgcgttcgcg gccatggtga
    15781 gcacccgatt ccaaagtagg tcaatggaaa gtagcttagc tccaagcggc ttacggtcaa
    15841 gctacttcct cgtcagctac tttcttgcgg gcaatcgacc cctcggcgga tactcgcccc
    15901 catgaagacg ccccaggacc cggtcgacgc gatcatcgag cagtgggcca ccgtccggcc
    15961 ggacctcgac accgccgcga tggaggtctt cggccgcgtc ttccggctcg cccgcacgat
    16021 gggcgaccgg atggagaagg cgtacgcgcc ctacgggatc tcgcgcgggg agttcgacgt
    16081 gctcgcgacc ctgcgtcgct cggacgcccc gtacaccctc tcgccccggc agctctcggc
    16141 gacgctcatg ctcaccaccg gcggcatgac cgggcgcctg gacaagctgg agcgcgcggg
    16201 gctgctacgg cgctcccccg acccgcacga ccggcgcgga ctccaggtga cgctcacgga
    16261 caaggggctg cggctcatcg acgaggccgt cggcgcgggg ctcgccgtcc agacggaggc
    16321 cctggcccac ctcgacgagg aacgagccgg tcaactggcc gccctgttgc gcgagttgct
    16381 gatgggcgcc ggagcctagg gtctcggcgg gcccccgagc ccggcccgga gggcctcagc
    16441 ccgccgcggc gacccggctc gacctgacgc gtatcacggt gagccggccc aggacctgag
    16501 ccagcgccat cagcagcagc gcggcggtcc aggcggcgga accggtgatc aggttgtcct
    16561 ggctgaaccg cgccaggctc ccggaaccgc catgagtggc ccagtactcg aatccggcgc
    16621 gcgaggccat gccgacgatc cacaggagcg cggcgagtgc cccggcgcgg gcgaacgcga
    16681 tcccgtccga ggcgcggctc agccgggtgg ccgcgccaca ggcgacgccc aggaccgcgc
    16741 cggcgacgac accggcgatg tcgagtccga ggtcgtgacc ttgggtcggg aaggacttga
    16801 ggtaataggc ggctgcggcg gcgacggccg cgagcggcag cagcgtgtgg tgcagcgtct
    16861 gccggacgcc tcggatctgc gggatcacga ggaggatgag ggatgcggag atcacgtagt
    16921 cggtcgtcgt catgcccatg agcttgcgct tcacgacgcg gaaccacctc ggctccaggg
    16981 tggagccgag ggtgggtttc cgcctcaacc cacgggttga ggtccaggat ccgtcttcaa
    17041 cggtccttgg atgatggtgg cgccactggc cggggtcgcc gtcgccccgc tggtcgtcgc
    17101 agtcgtagta cacgtactga tcgacgtcca gcgacgcccc ggcccgggcg agccaggcca
    17161 gcagggccgc gcccaggaag atgccctccg gctcccgctt cggggcgggt ccggtcgccg
    17221 cggccgtgcc cgcacctaca gtcaggcaca aggcggtcgc gagcgtgacg atcttctgtt
    17281 ttacgtgcag gtacatgcgt tcctcagggc gcggaccccc aggcgtcgtt cgacggcgcg
    17341 ggtccgcgct tcccccgggc ggtcgaacca ccctcgtgtt gcgcatacgt caaacgcatg
    17401 gtcgaaatca ccgtaaaccg ttaccaacgg tcatgctcaa ctcagcgtcc cacgcggtgg
    17461 cataccgctc ccgacgcggt gttgagatgc cagcgtttcc acggagcggc ggtcaccctc
    17521 gcgtcactcc cgccccgggc aaggtcagtt cgaagacgga tcctcgccca gcgccgccgc
    17581 caacgcccgc tcgacggcag tcgcgtcggg ggattcggcg gcccaggcca cgtatccgtc
    17641 gggccgcacc agcagggtcg tacgccggtc gctcgcccag ctctccacgg cgagacggtc
    17701 cttgcggccc ttgaggtcgt ccaggccgta cgcccggacg gccgccgtcg gtgcgacgag
    17761 gacgaaccgg ccgccgcgca gggcctcgta gaggcggccg cccttcagag tgacatcggg
    17821 ggcccgggtg ccgacgaggg cgtgcgagcc gcgcggggcc cggtaggcga agccgatgcc
    17881 ggtgatctgg cccgccgcct tccggcgcac ggggccgacg gcgttgagga ccgtggtgag
    17941 cacggagcgc agcgccagcg tccaggggta cttggccatc gcgagccgga cgatcccgcc
    18001 gctgctgcgc agcaccgcct tgccgacggg gtggcgctcg gcctggtagg tgtccaacaa
    18061 gtccgtgtcc gcatggccgt tgacgaccag cgcgagcttc cagctgaggt tcgccgcgtc
    18121 ctggaggccg gtgttcatgc cctgcccgcc ggccggggtg tggacatggg cggcgtcacc
    18181 ggcgaggaag acccggccga cccggtacgc gggcgcctga cgctcgtcgc tgtggaagcg
    18241 ggacatccag cgggcgtcgt gcatgccgta gtcatggccg agggagagcc ggacgatctc
    18301 cttgacctcg tcgagttcga gcggcgcgct gtcggggacg tcgcgaccgc ggtgccagcc
    18361 gatcacacgg tagtagccgt cgccgaaggg caccatgaag gcgaaggcgt cgccgacggc
    18421 gttggcggtg aggatcgact ccggctcctc ggcgagcagg acgtcggcga ggacgacgga
    18481 ccggatgacc gacttcccgg ggaacggcag ccccaccgcc tcacgcaccg cgctgcgcat
    18541 cccgtccgcc ccgaccacgt acgcggccgc catctccccc gccgccccgt ccgcaccgcg
    18601 gacttcgagc gtgacgcccg ccgcgtcctg gcgcagtccg gtcacctcgg tctcgtacac
    18661 gaaccgcacc ccggcctcga ccgcccgccg ctccaacgcc cgctccacct cgtactgcgg
    18721 gatcacgagc aggtggttga agcgggaggg gagcgtgtcg agggcgacgg agagcccgcc
    18781 gaagaggcgg atgcggtcga cggtccggcc gtgactctcc agctcgtcgg cgagaccgcg
    18841 ggcgtcgagc tgctccaggg tgcgggcgtg caggacgaag gcgcgggaga ggttgctgat
    18901 cccgtgcggg cgcttctcga cgagggtgac ggggacaccg gcggcggcga ggtccccggc
    18961 cagcaggagg ccggtggggc cggagccgac gacgatcacg tgccgggacc cgttggtgcc
    19021 gttcaccttg ccgttcgtct tgccgttcat ggcggcctcc tgatgccaac gtccgttggt
    19081 caacatttgt tggccaacgc ttgtttacca agatagggag cccgctctgg actgtcaaca
    19141 actgttggcc tacggttgtt ggcatgcccg acaaggaact ccccgcaccc gccgcgtccc
    19201 ccgcggcccg ccgttcggac accacccgca ccgccatcct caccgccgcg cgcgaacgct
    19261 tcgccgccga cggctacgag cgcgccacga tccgctcgat cgccaaggac gcacggatcg
    19321 atccgtcgat ggtgatgcgg tactacggct cgaaggaagg actgttcgcc gcggtcctcg
    19381 acgtcgacct gcggctgccg gacccggtcg ggctggaccc gcacgaggtg ggccgcgccc
    19441 tggtgggcca cttcctcgac ctctgggagg agaacgaggt cctcaccgtg ctgctccggg
    19501 tcggcgtgac caatccggac ggcgccgcgc gcatgcaggg catcttccgg gaccagctca
    19561 tgccggtcgc gctgcgcgtg tgccccgacc cggagcaggc gccggcacgg gccgcgctga
    19621 ccgcctcaca ggtgctgggc atggcgatgg cccgctacgt cctgcgattc ccgcccgccg
    19681 tcgcgctgcc ccgcgaggag gtcgtggcgt ggctggcgcc gacggtgcag cggtatctca
    19741 cggcgccgca tccgtaacgg gccccgaaag cccgtcgagg gactccgaaa acacgtcgag
    19801 ggagtcccca cacccggtag gtgcgcggac tccctcggtc gagaaggatc caggcctcgg
    19861 cgcgcggccg gggctccagg aagcgagccg gaatcaggtc cgcttcggct gcttgtcgga
    19921 cttgtccagg accatcacga ggcccgcgat gaccaggaac aggacgatcg gcgtcacgac
    19981 gtagaggccg agcgtttcga tcacgctcag gcccttgccg gggtcgtcac cgtcgtcgcg
    20041 ggtcagcgcg agcgcggggg acgacatgag cagcatcatc agcgtcgtac cggaagccag
    20101 ggcgccggcg cgcagggcgt tcttcttgtc cacggtgcaa acgtagcgaa cacctgaatg
    20161 agtcgcgcgc ccggggtgcc gtacggaggc cgcacccccg cccggacgcc ccgctcacgc
    20221 ccgctcacac gcctccgtca cgcccacgcg cactcccacc ctcaccccgg ccatcgctgc
    20281 ggcggtcatc gctcccgcgg ccatcacgtc caccgcgacc cccgaaccgt ccccgcagca
    20341 cgtcgatcag cgcgtacagc cggggcgagg ccgccagttc ctccagggtc accgggcggc
    20401 cttccgcgtc ggcgatgggc agccgccagt tcgggtactg gtcccacgtg cccggcaggt
    20461 tctgcggacg ccggtcgccg accgtgtccg ggagccacac gccgatcatg cgggccgggg
    20521 tgcgcagcag gaagcggtgc acggcctgga tctcggcctc ctccgacacc gccgaacccg
    20581 cgtcgcccgc cccgtgcagc agcccgaggc gggcgagcag cgccagccac tcccccgtgt
    20641 ccgccgtggc cgcggtccgc tcgtcctcca gggagccggt cagcaggccg agccggtcgc
    20701 ggagttcgac gtggtcgccg gtgagccggg aggcggtggg cggcaggtcg tgggtggtgg
    20761 cggtggccag gcagtcgggg cgccagcgct cggggggcag gggcttcccg tcgccgtccc
    20821 agtcccgttc gaaccacagc accgaggtgc cgagcacccc gcgctcgtgc agcgtctcgc
    20881 gtacgccggg ctcgaccgtg ccgaggtcct cgccgatcac cagggccccg gcccgcgagg
    20941 cctccagggt caggatcgcg agcatcgcct cggcgtcgta gcggacgtac gtgccctcgg
    21001 tgggcggctg tccctgcggc acccaccaga gccggaacag gcccatcaca tggtcgatgc
    21061 gcagggcgcc cgcgtgccgg aggagggcgc gcaggaggcg gcggtacggg gcgtagcccg
    21121 aggcggcgag gcggtccggg cgccagggcg gcaggcccca gtcctggccg cgtgcgttga
    21181 aggcgtccgg gggcgcgccg acggacatgc ccgccgcgaa gtactcctgc tgcgcccagg
    21241 cgtcggctcc gccgggatgc actccgaccg cgaggtcgtg cacgaggccc accgccatcc
    21301 cg
//
