LOCUS       NZ_CP041604            10405 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. S1A1-7 chromosome.
ACCESSION   NZ_CP041604
VERSION     NZ_CP041604.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S1A1-7
  ORGANISM  Streptomyces sp. S1A1-7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007113565.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:07:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,902
            CDSs (total)                      :: 10,801
            Genes (coding)                    :: 10,337
            CDSs (with protein)               :: 10,337
            Genes (RNA)                       :: 101
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 464
            CDSs (without protein)            :: 464
            Pseudo Genes (ambiguous residues) :: 0 of 464
            Pseudo Genes (frameshifted)       :: 185 of 464
            Pseudo Genes (incomplete)         :: 374 of 464
            Pseudo Genes (internal stop)      :: 46 of 464
            Pseudo Genes (multiple problems)  :: 127 of 464
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3544203
            Orig. end                         :: 3554608
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041604.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10405
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="14"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10405
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10405
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5405](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     gene            complement(262..1110)
                     /locus_tag="FNV64_RS17610"
                     /old_locus_tag="FNV64_17900"
     CDS             complement(262..1110)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121392.1"
                     /locus_tag="FNV64_RS17610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17900"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_054232281.1"
                     /transl_table=11
                     /translation="MNSVLGRRTRILAATTATAGLLLVAGCSSGGGGGQSSAKGVPLVK
                     AGQVTTCTHLPYPPFQSEINGKVQGFDVALIDLVAGDLGVKQAIVDTPFENFKTGAFLN
                     SGQCDLAAAGMTITPERKKNVDFSDPYFDATQAVLVDKKSGVNSLADVKAKGKKLGAQA
                     QTTGEEYAAKQGFDSVSFESSDAVLNGLRTGQVQAVIIDYPVVQGWLKDKANADAFKVV
                     DNLNTGEQYGFTVKKGNTKLLAEINRAIKQAKADGTYKKLYEKWIGPYPASAATASPSA
                     S"
     gene            1348..2448
                     /locus_tag="FNV64_RS17615"
                     /old_locus_tag="FNV64_17905"
     CDS             1348..2448
                     /NRPS_PKS="Domain: Aminotran_5 (73-258). E-value: 1.2e-25.
                     Score: 82.1. Matches aSDomain:
                     nrpspksdomains_FNV64_RS17615_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477727.1"
                     /locus_tag="FNV64_RS17615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17905"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_143657027.1"
                     /sec_met_domain="Aminotran_5 (E-value: 1.2e-19, bitscore:
                     69.8, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPFLDLAPLSAAHFAAIEDRVARLLSTEQDVVIMQGEALLPLE
                     GAIRAAAGPGTTALNVITGPYGQTFGDWLRDCGATVIDLAVPFHTAVTAAQVRDAFAEH
                     PEIDFVSLVHAEAATGNTNPVAEIGEVVRAHGALFYLDAVASIGAEPVLPDAWGVDLCV
                     IGAQKAMGGPAGVSAVSVSERAWARMAANPGAPRRSYLSLLDWKERWVDGGRKALLHAP
                     AQLEMLALEACVERIEAEGLDAVMRRHALAGAATRAGAVALGGGLEPYVYEAGDAAPVA
                     TTLRAPSGVDAGVLVARALTADPALPLVAGGGALAKEMIRVNHYGPDATPGVVHSCLAA
                     LGAAMAESGLTIDLEAARRATTKAWS"
     aSDomain        1567..2121
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV64_RS17615_Aminotran_5.1"
                     /evalue="1.20E-25"
                     /label="FNV64_RS17615_Aminotran_5.1"
                     /locus_tag="FNV64_RS17615"
                     /protein_end="258"
                     /protein_start="73"
                     /score="82.1"
                     /tool="antismash"
                     /translation="LRDCGATVIDLAVPFHTAVTAAQVRDAFAEHPEIDFVSLVHAEAA
                     TGNTNPVAEIGEVVRAHGALFYLDAVASIGAEPVLPDAWGVDLCVIGAQKAMGGPAGVS
                     AVSVSERAWARMAANPGAPRRSYLSLLDWKERWVDGGRKALLHAPAQLEMLALEACVER
                     IEAEGLDAVMRRHALAGAATRA"
     misc_feature    2869..2884
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    3003..3015
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            3040..3579
                     /gene="ectA"
                     /locus_tag="FNV64_RS17620"
                     /old_locus_tag="FNV64_17910"
     CDS             3040..3579
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015661364.1"
                     /locus_tag="FNV64_RS17620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17910"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_095855368.1"
                     /transl_table=11
                     /translation="MTAARADLQAEFLEMPEGLRIDRPKVADGAALWHIAKDSGTLDLN
                     SSYSYLLWCRDFAGTSAVARDADGVPVGFVTGYVRPERPGTLLVWQVAVDAAHRGRGLA
                     AALLDGLTARVAEQRTITAVETTITPGNTASERLFTSYARRHGARVEHEVLFEAGQFPD
                     GPHDPEVLYRIGPLPG"
     gene            3668..4939
                     /gene="ectB"
                     /locus_tag="FNV64_RS17625"
                     /old_locus_tag="FNV64_17915"
     CDS             3668..4939
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-366). E-value: 2.2e-72.
                     Score: 235.8. Matches aSDomain:
                     nrpspksdomains_FNV64_RS17625_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381147.1"
                     /locus_tag="FNV64_RS17625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17915"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_097284147.1"
                     /sec_met_domain="Aminotran_3 (E-value: 9.9e-77, bitscore:
                     257.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIIQPDLSVFETLESEVRSYCRSWPTVFDRARGSRMFDEDGHEY
                     LDFFAGAGSLNYGHNNPVLKRALIDYLERDGVTHGLDMSTTAKRAFLEAFQNLVLRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGREAIVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDHYFDGQVPDFLWFERLLEDQGSGLNQPAAVIVETVQGEGGINVARP
                     EWLRALADLCRRRDMLLIVDDIQMGCGRTGAFFSFEEAGIVPDIVTVSKSISGYGLPMS
                     LCLFKPELDVWEPGEHNGTFRGNNPAFVTAAAALETYWSDGSAMEKQTRARGEQIEQAL
                     ISVTEENLADVKEYRGRGLVWGLEFHEKERAGRVAQRAFELGLLIETSGPESEVVKLLP
                     ALTITPDELDEGLRTVARAVRETV"
     aSDomain        3752..4765
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV64_RS17625_Aminotran_3.1"
                     /evalue="2.20E-72"
                     /label="FNV64_RS17625_Aminotran_3.1"
                     /locus_tag="FNV64_RS17625"
                     /protein_end="366"
                     /protein_start="28"
                     /score="235.8"
                     /tool="antismash"
                     /translation="FDRARGSRMFDEDGHEYLDFFAGAGSLNYGHNNPVLKRALIDYLE
                     RDGVTHGLDMSTTAKRAFLEAFQNLVLRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     REAIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDHYFDGQVPDFLWFER
                     LLEDQGSGLNQPAAVIVETVQGEGGINVARPEWLRALADLCRRRDMLLIVDDIQMGCGR
                     TGAFFSFEEAGIVPDIVTVSKSISGYGLPMSLCLFKPELDVWEPGEHNGTFRGNNPAFV
                     TAAAALETYWSDGSAMEKQTRARGEQIEQALISVTEENLADVKEYRGRGLVWGLEFH"
     gene            5001..5405
                     /locus_tag="FNV64_RS17630"
                     /old_locus_tag="FNV64_17920"
     CDS             5001..5405
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643612.1"
                     /locus_tag="FNV64_RS17630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17920"
                     /product="ectoine synthase"
                     /protein_id="WP_054232284.1"
                     /sec_met_domain="ectoine_synt (E-value: 3e-53, bitscore:
                     178.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFKDIEGTDRHVKAATGTWESKRIVLAKEKVGFSLHETVLY
                     AGTETSMWYANHIEAVLCVAGEAELTNDETGETHWITPGTMYLLDGHERHTMRPKTDFR
                     CVCVFNPPVTGREDHDENGVYPLLTEPEEV"
     gene            5412..6323
                     /gene="thpD"
                     /locus_tag="FNV64_RS17635"
                     /old_locus_tag="FNV64_17925"
     CDS             5412..6323
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477733.1"
                     /locus_tag="FNV64_RS17635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17925"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_143601269.1"
                     /sec_met_domain="PhyH (E-value: 2.9e-38, bitscore: 131.5,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTTTTSTTTVTDLYPSRGATEVSVPRQDPVVWGTPGTPGPFSV
                     PDLQAYERDGFLAIEELIGEDDVALYRAELERLVTDPAIRADERSIVEPATQEIRSVFE
                     VHRISEVFAALVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAE
                     DGLANMRTVSVSIALTENHDTNGGLMIMPGSHKTFLGCAGATPRDNYKKSLQMQDAGTP
                     SDEALTRFADRHGIKLFTGRAGSATWFDCNCMHGSGDNITPFPRSNVFIVFNSVENAAV
                     EPFAAPVRRPEFIGARDFTPVQ"
     gene            complement(6387..7436)
                     /locus_tag="FNV64_RS17640"
                     /old_locus_tag="FNV64_17930"
     CDS             complement(6387..7436)
                     /NRPS_PKS="Domain: Aminotran_5 (16-343). E-value: 1.9e-24.
                     Score: 78.2. Matches aSDomain:
                     nrpspksdomains_FNV64_RS17640_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477739.1"
                     /locus_tag="FNV64_RS17640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17930"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_143654807.1"
                     /sec_met_domain="Aminotran_5 (E-value: 5.6e-18, bitscore:
                     64.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METFESLVRAEFAPKNTYLNTASCGLLPARTVEAMRVAVESVADG
                     RPSDMFDDVEAARAAFARLAGVPAGRVAAGASVAVYSGLIAASLPPGAEVLTAEDDFSS
                     VVNPFHVRGDLKLRAVPLERIAESVRPGTALVAVSAAQSADGRIADLAGIARAAREHGA
                     RTYVDVSQAAGWLPIQADAYDFVSSVAFKWLVCPRGVAFLVVPEDLGGLTPVFAGWVAG
                     EAPWDSCYGPVAELAHSARRFDESPSLFSYAGARHSLELFEELGVANVRAHDLALADRF
                     RAGLQGLGHTPVSAPGSPIVSVPGLGRRQQELSEAGVEVSDRAGNLRAAFHLYNTPADV
                     DRLLDVLSG"
     aSDomain        complement(6408..7388)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV64_RS17640_Aminotran_5.1"
                     /evalue="1.90E-24"
                     /label="FNV64_RS17640_Aminotran_5.1"
                     /locus_tag="FNV64_RS17640"
                     /protein_end="343"
                     /protein_start="16"
                     /score="78.2"
                     /tool="antismash"
                     /translation="TYLNTASCGLLPARTVEAMRVAVESVADGRPSDMFDDVEAARAAF
                     ARLAGVPAGRVAAGASVAVYSGLIAASLPPGAEVLTAEDDFSSVVNPFHVRGDLKLRAV
                     PLERIAESVRPGTALVAVSAAQSADGRIADLAGIARAAREHGARTYVDVSQAAGWLPIQ
                     ADAYDFVSSVAFKWLVCPRGVAFLVVPEDLGGLTPVFAGWVAGEAPWDSCYGPVAELAH
                     SARRFDESPSLFSYAGARHSLELFEELGVANVRAHDLALADRFRAGLQGLGHTPVSAPG
                     SPIVSVPGLGRRQQELSEAGVEVSDRAGNLRAAFHLYNTPADVDRL"
     gene            complement(7553..8272)
                     /locus_tag="FNV64_RS17645"
                     /old_locus_tag="FNV64_17935"
     CDS             complement(7553..8272)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067467.1"
                     /locus_tag="FNV64_RS17645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17935"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_143654808.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYVGKARFEKALDAFPHRDEVEVVHRSFELDP
                     GRAKGDIQPVLKMLTKKYGMSEAQAQAGEENLGAQATAEGLAYRTRDRDHGNTFDMHRL
                     LHFAKERGRQDELIGLLYKANFAEERTVFNDDERLVELAVAAGLDADASREVLADPKAY
                     ADEVRADEREAAELGANGVPFFVLDRKYGVSGAQPAEVFAQALTQAWGERPPLKLIQDG
                     AADAEACGPDGCAVPQP"
     gene            complement(8350..8856)
                     /locus_tag="FNV64_RS17650"
                     /old_locus_tag="FNV64_17940"
     CDS             complement(8350..8856)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002240.1"
                     /locus_tag="FNV64_RS17650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17940"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_143654809.1"
                     /transl_table=11
                     /translation="MISTPGTTGPLVIRTALPSEAAAITELHLRARSTYYPDGLPFGDV
                     DWVAAWRGSIERPEAHVLCAVRDGHLVGIASFRTADDAPADTVKLFQFHVDPDCWRQGI
                     GRVLHSACLEQWRADGKHTATLDVHVDNARAQAFYARQGWVPDPENPPAEGDHHLFLRY
                     AVTGE"
     gene            complement(8921..9529)
                     /locus_tag="FNV64_RS17655"
                     /old_locus_tag="FNV64_17945"
     CDS             complement(8921..9529)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436202.1"
                     /locus_tag="FNV64_RS17655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_17945"
                     /product="DUF1349 domain-containing protein"
                     /protein_id="WP_054232288.1"
                     /transl_table=11
                     /translation="MDVELPELPFPLRTYGPDGHWSHEDGILTGWAGPRQDRFVPPTDE
                     ALDPASDAPRLLGAPEGDFQLIARVTVGFGAAFDAGVLYVHVGERAWAKLCLEYSPDVP
                     TVCTVVTRGHSDDANSFTVDGSSVWLRISRTGRAFAFHASRDGKRWTFIRLFTLGEEKE
                     TSAALVGFMTQSPMGEGCVVTYDGIEFRPNWPKDLRDGS"
ORIGIN
        1 ggccgagcac gagaccgacg acgaagccgg acatcgtgta gagcacggtg ttcttcagcg
       61 ccagtgtgat gacgtccggg aacatctgct tgaccaggtc ccactgcgcg aactggttct
      121 tcagacgtcc ccagtccgcc gtgaccgcga aggcgatcac ggcggcgacg aagacgacgt
      181 actgcgcgcc gcgcgagagg gcgcgcttct ggcgccgggt caggccggac tttcggggct
      241 ggagccgtgc gtcggcatca ctcatgaggc ggacggcgag gcggtggccg cggacgcggg
      301 gtacgggccg atccacttct cgtagagctt cttgtacgta ccgtcggcct tggcctgctt
      361 gatcgccctg ttgatctcgg cgaggagctt ggtgttgccc ttcttgaccg tgaagccgta
      421 ctgctcaccg gtgttgaggt tgtcgaccac cttgaaggcg tcggcgttcg ccttgtcctt
      481 cagccagccc tggacgaccg ggtagtcgat gatgacggcc tggacctggc cggtgcgcag
      541 gccattcagg accgcgtcgg aggactcgaa ggagaccgag tcgaagccct gcttcgccgc
      601 gtactcctcg cccgtggtct gcgcctgggc gccgagcttc ttgcccttgg ccttcacgtc
      661 ggcgagggag ttgacgccgc tcttcttgtc gaccaggacg gcctgggtgg cgtcgaagta
      721 cgggtcggag aagtcgacgt tcttcttgcg ctccggggtg atcgtcatgc cggccgcggc
      781 gaggtcgcac tggccggagt tgaggaacgc gcccgtcttg aagttctcga agggcgtgtc
      841 gacgatggcc tgcttcacgc cgaggtcccc cgcgaccagg tcgatcagcg cgacgtcgaa
      901 gccctgcacc ttgccgttga tctccgactg gaacggcgga tacgggaggt gggtacaggt
      961 cgtgacctgg cccgccttga ccaggggaac gcccttggca ctgctctggc cccctccgcc
     1021 gcccgaggag cagccggcca cgagcagcag cccggccgtg gcggtggtgg cggccagaat
     1081 gcgcgtccgg cgtccgagga ccgagttcac ggagacctcc tgtgggggga atggaggatt
     1141 ccgattataa ggaaaggttt ggctcgctca aaccaatccg atggctgttg cgccgttcgg
     1201 cctcagaagt catgcctcgt gcggccgtcc ggtcgtacga cctgggggtg tccgctcgta
     1261 cgcccgagga tcgccgcggg cgtgacaagg gcgcccggat acgctcgggg ctgcgcattg
     1321 gaacctgtga gcgaagagag caccgccgtg acccatccct tcctggacct cgccccgctg
     1381 agcgccgcac acttcgcggc gatcgaggac cgcgtggcgc ggctgctctc caccgagcag
     1441 gacgtcgtga tcatgcaggg cgaggcgctg ctgcccctgg agggtgccat tcgcgccgcg
     1501 gccgggcccg gcaccaccgc gctcaacgtg atcaccgggc cgtacgggca gaccttcggg
     1561 gactggctgc gggactgcgg cgcgacggtg atcgacctcg cggtgccgtt ccacacggcg
     1621 gtgacggccg cacaggtgcg tgacgccttc gccgagcatc cggagatcga cttcgtctcg
     1681 ctggtgcacg cggaggcggc gacgggcaac acgaaccccg tcgcggagat cggcgaggtc
     1741 gtgcgtgcgc acggcgcgct gttctacctc gacgccgtcg cctcgatcgg cgcggagccg
     1801 gtgctgccgg acgcgtgggg ggtcgacctg tgcgtgatcg gggcacagaa ggcgatgggc
     1861 gggccggccg gggtgtcggc cgtgtccgtg agcgagcggg cgtgggcgcg gatggccgcc
     1921 aatccggggg cgccgcgtcg gtcctacctc tccctgctgg actggaagga gcggtgggtc
     1981 gacggcgggc gcaaggcgct gctgcacgcg ccggcgcagc tggagatgct ggcgctggag
     2041 gcgtgtgtcg agcggatcga ggcggagggg ctcgacgcgg tgatgcgccg ccatgccctg
     2101 gcgggggcgg ccacgcgggc gggggcggtc gctctcggtg gcgggctgga gccgtatgtg
     2161 tacgaggcgg gggacgccgc gccggtcgcc acgacgttgc gggcgccgtc cggggtcgat
     2221 gcgggggtgc tggtcgcgag ggcgttgacc gcggatccgg cgttgccgtt ggtcgcgggt
     2281 gggggtgcgc tggcgaagga gatgatccgg gtgaaccact acggccccga tgcgacgccg
     2341 ggggtcgtgc actcctgcct cgcggcgctg ggggcggcga tggccgagtc cggtctcacg
     2401 atcgacctgg aagcggcacg ccgcgcgacg acgaaggcgt ggtcctagcc gtacgtcacg
     2461 ggcgggtgtg tcgggtgcgg gtgggtgggg gcttggcgcg cagttccccg cgcccctggg
     2521 gcgcggggct gcgccccggc gccccatcgg ccccgtcctc gcgcgccgga cgagctggac
     2581 gcttttaggg gcgcggggaa ctgcgcgacc agcccccacc cacccgcacc cgaagaacac
     2641 accgggatcc ggggcggagc cccggcgtgt tctccccacg gagttaccgg ggcttaatcg
     2701 cgcatcaatt gacgaggcgc tcaccatggc actcgccatg cttattcttg cattaactcg
     2761 aagattagct tcccgtattc ttctgcccgc tttccccgtc cctaaacgca aagatttcgc
     2821 gaacgccaac cgacgtaatt cgggcacgtc tcgtggtgat tacgtgtctg tgacgcactc
     2881 cacactgcgt ccacttcctc ccctattttc cgggcaaacc gtccccttgt accactcgca
     2941 gcaccccgct ctcacgggcg cgtgataaca caacggcgcg tcgtacgtaa ccccggacga
     3001 cgatgcaatt tgagatttcc ctcggtaaat tcaatccgca tgaccgccgc acgagcagac
     3061 ctgcaagcgg aattcctgga aatgccggag ggccttcgga tcgaccgtcc gaaggtggcg
     3121 gacggagccg cgctctggca tatcgccaag gactccggaa ccctcgacct gaactcctcg
     3181 tacagctatc tgctgtggtg tcgtgacttc gccggtacgt cggcggtggc gcgcgacgcg
     3241 gacggtgtgc ccgtcggctt cgtcaccggg tacgtccggc ccgagcgtcc gggcaccctg
     3301 ctcgtgtggc aggtggccgt cgacgccgcc caccgcggac gcggactggc cgcggccctg
     3361 ctcgacgggc tgaccgcgcg ggtcgcggaa cagcggacga tcaccgccgt cgagaccacg
     3421 atcacgcccg gcaacaccgc ctccgagcgc cttttcacct cgtacgcgcg acgccacggc
     3481 gcgcgcgtcg agcacgaagt gctgttcgag gccgggcagt tcccggacgg accgcacgac
     3541 cccgaagtgc tctaccggat cggtccgctc cccggctgac cccgcgccgg ccccggccga
     3601 cccggacacc cccctggctt ccccctgcct tctccccctc cccccacgca ccgaggagcg
     3661 attcgccgtg accatcatcc agcccgacct gagcgtcttc gagaccctgg agtcggaggt
     3721 gcgcagctac tgccgcagct ggcccacggt cttcgaccgg gctcggggca gccggatgtt
     3781 cgacgaggac gggcacgagt acctcgactt cttcgccggc gcggggtccc tcaactacgg
     3841 gcacaacaac cccgtactca aacgggccct catcgactac ctggagcgcg acggcgtcac
     3901 ccacggtctc gacatgtcga cgaccgccaa gcgcgccttc ctggaggcat tccagaatct
     3961 cgtcctacgg ccgcgcgacc tgccgtacaa ggtcatgttc ccggggccga caggcaccaa
     4021 cgccgtcgag tccgcgctga agctggcgcg gaaggtgaag gggcgcgagg cgatcgtgtc
     4081 cttcaccaac gccttccacg ggatgtcgct gggctcgctg gccgtgaccg ggaacgcctt
     4141 caagcgggcc ggtgccggga ttccgctcgt gcacgggacc ccgatgccgt tcgaccacta
     4201 cttcgacggc caggtgccgg acttcctctg gttcgagcgg ctgctcgagg accaggggtc
     4261 ggggctcaac cagcccgccg cggtcatcgt cgagaccgtg cagggcgagg gcggcatcaa
     4321 cgtcgcccgg cccgagtggc tgcgcgccct cgccgacctg tgccggcggc gcgacatgct
     4381 gctcatcgtc gacgacatcc agatgggctg cgggcggacg ggagcgttct tctccttcga
     4441 ggaggcgggg atcgtgcccg acatcgtgac cgtgtccaag tccatcagcg ggtacgggtt
     4501 gcccatgtcg ctgtgcctgt tcaagcccga actggacgtc tgggagccgg gcgagcacaa
     4561 cggcacgttc cgcggcaaca accccgcgtt cgtcaccgcc gccgcggccc tggagacgta
     4621 ctggtccgac gggtccgcca tggagaagca gacccgtgcc cgcggggagc agatcgagca
     4681 ggccctgatc tccgtcaccg aggagaacct cgccgacgtg aaggagtacc ggggacgcgg
     4741 tctcgtctgg ggcctcgagt tccacgagaa ggagcgtgcg gggcgcgtcg cgcagcgcgc
     4801 cttcgaactc gggctgctca tcgagacctc aggcccggag agcgaggtcg tgaaactcct
     4861 ccccgcgctc accatcaccc ccgacgagct cgacgagggc ctgcgcaccg tcgcccgcgc
     4921 cgtacgcgaa accgtctgac cgacgtccac ggacgtccgg cagacatctg acagatctga
     4981 cagaaaggca cggcaccacc gtgatagtcc gttcgttcaa ggacatcgag ggcaccgacc
     5041 ggcatgtgaa ggccgcgacg ggtacctggg agagcaagcg catcgtcctc gccaaggaga
     5101 aggtgggctt ctccctccac gagacggtcc tgtacgcggg tacggagacg tccatgtggt
     5161 acgcgaacca catcgaggcc gtgctctgcg tggcgggcga ggccgagctg accaacgacg
     5221 agaccggtga gacgcactgg atcacaccgg gcacgatgta cctgctcgac ggccacgagc
     5281 gccacaccat gcgccccaag accgacttcc ggtgcgtctg cgtcttcaat ccgcccgtca
     5341 cgggacggga ggaccacgac gagaacggcg tctacccgct gctcaccgaa cccgaggagg
     5401 tctgaagccc catgaccacg accaccacga ccagcacgac caccgtcacc gatctctacc
     5461 ccagccgcgg cgccaccgag gtgtccgtcc cccgccagga cccggtcgtc tggggcacgc
     5521 ccggcacgcc ggggccgttc tccgtgcccg acctccaggc gtacgagcgt gacggcttcc
     5581 tcgcgatcga ggagctgatc ggcgaggacg acgtcgccct ctaccgggcc gagttggagc
     5641 ggctggtcac cgatccggcg atccgcgccg acgagcgctc gatcgtcgag cccgccactc
     5701 aggagatcag gtccgtcttc gaggtgcacc ggatcagcga ggtcttcgcc gcgctcgtac
     5761 gcgacgagcg ggtcgtcggg cgggcccgcc agatcctcgg ctcggacgtc tacgtccacc
     5821 agtcgcggat caacgtcaag ccgggcttcg gggccagcgg gttctactgg cactcggact
     5881 tcgagacctg gcacgccgag gacgggctgg cgaacatgcg gaccgtgtcc gtgtcgatcg
     5941 cgctgaccga gaaccacgac accaacggcg gcctcatgat catgccgggg tcgcacaaga
     6001 cgttcctcgg ctgtgcgggg gccaccccgc gggacaacta caagaagtcg ctccagatgc
     6061 aggacgcggg caccccgtcc gacgaggcgc tgacccgctt cgccgaccgg cacggcatca
     6121 agctcttcac gggccgggcc ggttcggcga cctggttcga ctgcaactgc atgcacggct
     6181 ccggggacaa catcaccccg ttcccgcgca gcaacgtctt catcgtgttc aacagcgtgg
     6241 agaacgcggc ggtggagccg ttcgcggcgc cggtccgcag gcccgagttc atcggcgccc
     6301 gtgatttcac gcccgtgcag tgaccgcgag cgtgacgtgg ccgcacgcgt gacgtggccg
     6361 cgagcgtgaa ggagcccccg ccggggtcag ccggacagga cgtccagcag tcggtcgacg
     6421 tcggcggggg tgttgtacag gtggaaggcc gcgcgcaggt tgcccgcccg gtcggacacc
     6481 tcgaccccgg cctcgctcag ctcctgctgc cgccggccga gtccgggcac ggacacgatc
     6541 ggcgagccgg gggcggaaac cggcgtgtgg ccgagcccct ggagcccggc gcggaaacgg
     6601 tcggcgaggg cgaggtcatg ggcgcgtacg ttcgccacgc ccagctcctc gaagagctcc
     6661 agcgagtgcc gggcgcccgc gtacgagaag aggctggggc tctcgtcgaa ccgccgcgcc
     6721 gagtgggcga gttccgccac cgggccgtag cagctgtccc agggcgcctc acccgcgacc
     6781 cagccggcga acacgggagt cagcccgccg aggtcctccg gaacgaccag gaaggccacg
     6841 ccccgagggc agacgagcca cttgaaggcg accgaggaga cgaagtcgta cgcgtcggcc
     6901 tggatcggca gccagccggc ggcctgggag acgtcgacgt acgtacgcgc cccgtgctcg
     6961 cgcgcggccc gggcgatgcc cgccagatcg gcgatccgcc cgtccgcgga ctgcgcggcg
     7021 ctgaccgcga cgagcgcggt gcccggacgt acggactcgg cgatccgctc cagcggtacg
     7081 gcgcgcagct tgaggtcgcc acggacgtgg aaggggttca cgacggagct gaagtcgtcc
     7141 tccgcggtga ggacttcggc gcccggcggc agcgaggcgg cgatcagtcc gctgtagacg
     7201 gcgaccgagg ccccggccgc cacccggccc gcggggaccc cggccagccg ggcgaaggcg
     7261 gcgcgggcgg cctccacgtc gtcgaacatg tcggacggcc gtccgtcggc gacggactcg
     7321 acggcgacgc gcatggcctc gaccgtgcgc gccggcagga gtccgcagct cgcggtgttc
     7381 agataggtgt tcttcggggc gaactcggct cgtacgaggc tctcgaaggt ctccatggga
     7441 ccactgtgcg gccccgagca cctctcgtcc attacggaat tttgcgtggt tccggtaagg
     7501 actgcttata cgtccgcccc gacctgcgct ttcaccaccg tgccggacgg gcttacggct
     7561 gcggtacggc gcatccgtcc gggccgcagg cctccgcgtc ggcggcaccg tcctggatca
     7621 gcttcagcgg cgggcgttcg ccccacgcct gggtcagggc ctgcgcgaag acctcggcgg
     7681 gctgggcgcc ggagacgccg tacttgcggt ccaggacgaa gaacggcacg ccgttcgcgc
     7741 cgagctcggc ggcctcgcgc tcgtcggcgc gcacctcgtc ggcgtacgcc ttagggtcgg
     7801 ccagcacctc gcgggacgcg tcggcgtcga gcccggcggc gacggccagc tcgacgagcc
     7861 gctcgtcgtc gttgaagacg gtccgctcct ctgcgaagtt cgccttgtac agcaggccga
     7921 tcagttcgtc ctggcggccc cgctccttgg cgaagtggag gaggcggtgc atgtcgaagg
     7981 tgttgccgtg gtcgcggtcc cgggtgcggt aggccaggcc ctcggcggtg gcctgggcgc
     8041 ccaggttctc ctcgccggcc tgtgcctgtg cctcgctcat gccgtacttc ttggtcagca
     8101 tcttgagcac gggctggatg tcgcccttgg cgcgaccggg gtccagctcg aaggagcggt
     8161 gcacgacctc gacctcgtcg cggtgcggga aggcgtccag cgccttctcg aagcgggcct
     8221 tgcccacgta gcaccaggga caggcgatat ccgaccagat ctcgacgcgc atgtcttcgg
     8281 ctctctccag gtcgtacgaa tacgggcccc tccgggggca ggagtatgtg aacgttcaaa
     8341 cggccggttt cattccccgg tgacggcgta gcgcaggaag aggtggtgat cgccttcggc
     8401 gggcgggttc tccgggtccg ggacccagcc ctggcgggcg tagaaggcct gggcgcgggc
     8461 gttgtcgacg tgcacgtcga gggtggcggt gtgcttgccg tcggcccgcc actgttcgag
     8521 acaggccgag tgcagtaccc ggccgatgcc ctggcgccag cagtcgggat cgacgtggaa
     8581 ctggaagagc ttcacggtgt cggcgggcgc gtcgtcggcc gtccggaagg aggcgatgcc
     8641 caccaggtgt ccgtcacgca ccgcgcagag gacatgggcc tcggggcgct cgatgctgcc
     8701 ccgccacgcg gcgacccagt ccacgtcgcc gaagggcagg ccgtccgggt agtacgtgga
     8761 gcgggcgcgg aggtgcagct cggtgatggc ggcggcctcg ctgggcaggg cggttctgat
     8821 gacgaggggg cccgtggtgc cgggtgtgct gatcatgcag cggaggacgt ggtggagggg
     8881 ggccacggtt cccaccccgc ggccgacccc ccacccacgg tcagctgccg tctctcaggt
     8941 ccttgggcca gttcgggcgg aactcgatgc cgtcgtacgt caccacgcac ccctccccca
     9001 tcggcgactg cgtcatgaag ccgacgagcg cggcggacgt ctccttctcc tcacccaggg
     9061 tgaagagccg gatgaacgtc cagcgcttgc cgtcgcggga ggcgtggaag gcgaaggccc
     9121 gacccgtgcg gctgatccgc agccagacgg aactgccgtc cacggtgaag gagttggcgt
     9181 cgtcggagtg cccccgggtg accaccgtgc agacggtggg cacgtccggg gagtactcca
     9241 ggcagagctt cgcccaggcc cgctccccca catggacgta gaggaccccc gcgtcgaagg
     9301 ccgcgccgaa gccgaccgtg acgcgggcga tcagctggaa gtccccctcc ggcgccccga
     9361 ggagacgggg cgcgtcggag gccgggtcca gtgcctcgtc ggtgggcggt acgaaacggt
     9421 cctggcgggg gccggcccag ccggtgagta tcccgtcctc gtgcgaccag tgcccgtcag
     9481 gcccgtaggt acggaggggg aagggaagtt cgggaagttc gacgtccatt caccaattct
     9541 ctcaggccaa gtaccgcgcc ccgaaagggg cgcgaggaac tgcgcgacca gccacaacgg
     9601 ccccgcagcc cgcgaacgac cacacccccg acggcgctac ccgcggagcg ctaccgctcc
     9661 aggtgaccgt catagcgtcg cggcagcccc agcgggttgt cgtcccgcag ctccggcggc
     9721 agcagcgcct ccggcgcgtt ctggtacgcc accggccgca gccagcgctc gatcgccgta
     9781 ccgccgaccg acgtcgaggt agacgtcgtc gccgggtagg gaccgccgtg gtgctgggcg
     9841 ggggcgacgg cgacaccggt gggccagccg ttgaccagga cgcgcccggc gagcggcgtc
     9901 agctcggcga ggatctccgc gccgcggcct tcgcccgccg cctcctccgt cgacaactgc
     9961 acggtggcgg tgaggttgcc gggaaggcgc gagaggaccg cgctggcctc ggactcgtcc
    10021 tcgtagcggg cgacgaccgt gagcgggccg aagcactcct ccaggagcag gtcgtgctcg
    10081 ccctcggtga cgagcttctg cgcgggcacg gtcaggaagc cggggctcac cgtgtgctcg
    10141 ccgcccgagc ccggggtcac cggggactcg acgccgggga gcccggcgcg ctcggcgaca
    10201 cccgcgatga agttgtcgcg catgcggtgg tccaggagaa cgcccgcgtc ggtgtcgctg
    10261 acggcgtcgg tcagggactt caccaggcgg tcgcccgccg cacccgcggg cgccaggacc
    10321 aggcccggct tcacgcagaa ctggccgacg cccagcgtca tcgagcccgc gagcccggcg
    10381 ccgatcgcct cggcgcgctc ggccg
//
