LOCUS       NZ_CP041604            21970 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. S1A1-7 chromosome.
ACCESSION   NZ_CP041604
VERSION     NZ_CP041604.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S1A1-7
  ORGANISM  Streptomyces sp. S1A1-7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007113565.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:07:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,902
            CDSs (total)                      :: 10,801
            Genes (coding)                    :: 10,337
            CDSs (with protein)               :: 10,337
            Genes (RNA)                       :: 101
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 464
            CDSs (without protein)            :: 464
            Pseudo Genes (ambiguous residues) :: 0 of 464
            Pseudo Genes (frameshifted)       :: 185 of 464
            Pseudo Genes (incomplete)         :: 374 of 464
            Pseudo Genes (internal stop)      :: 46 of 464
            Pseudo Genes (multiple problems)  :: 127 of 464
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1902610
            Orig. end                         :: 1924580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041604.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21970
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="melanin"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..21970
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            293..565
                     /locus_tag="FNV64_RS55110"
     CDS             293..565
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS55110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_240363356.1"
                     /transl_table=11
                     /translation="MPQGRDRAPVSRSLRTTALAALPSAVLAAVHYAPVVSTFGPLRDR
                     TMPRLSGRAHADRIVLNVDAGPDPLSTPFFRDCSTGAGCAPPSSC"
     gene            879..1004
                     /locus_tag="FNV64_RS56210"
     CDS             879..1004
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS56210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_266943745.1"
                     /transl_table=11
                     /translation="MHLALESDPDPEAVLARFIDRLPATDEELLRQPLGNLPEER"
     gene            1167..2483
                     /locus_tag="FNV64_RS10265"
                     /old_locus_tag="FNV64_10455"
     CDS             1167..2483
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_10455"
                     /product="hypothetical protein"
                     /protein_id="WP_143654467.1"
                     /transl_table=11
                     /translation="MRRLPPRKPMVVDRPTPRPAVWMAGAGIALFALVGASAPNHNTLR
                     APIPWLRLPAMAGTVSQTATIAAIVLSCWGTLGMLKAHERGWRPDARLLFRLGAMTALA
                     VANLTPVGSSDTASYAAYGRIAALGGDPYVTTPARLGGAYAHLVSEAWRNTPSVYGPVA
                     TWWQGAAAFIGQERPWLTIWALMLANAAVFVGTGYLLLRTADDPVRAGLVWSVNPLLIG
                     VLVEGGHLDTLVAGLAVCAVHLARRTTRWHHDLIVGGLVGLACGVKISACLFGVGLAWP
                     LLRSGRWRPAARQACAAALTLAALYGAYGAHALVPLSAASQLVSAPSVWAVFDQCATAV
                     LGPGSTAAIVSVLWPVVMLALAWVLRRRAAPDAPSVIAVPFALAFAWVLAAPWSMPWYT
                     ALAWALTALFSQGRPTQYLTVATAVLALSHNSGGHGWTW"
     gene            2614..3831
                     /locus_tag="FNV64_RS10270"
                     /old_locus_tag="FNV64_10460"
     CDS             2614..3831
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_10460"
                     /product="hypothetical protein"
                     /protein_id="WP_143654468.1"
                     /transl_table=11
                     /translation="MADQSSRPARSGAAWHWWFLGLWATVWFLADLHGGGYSWHYFANG
                     STLLFSGSGASPAGGLHLYANYPNLQIGPAAFLCAWVLGNLGGVVAAQLTMMGVGLLVL
                     RLIEQTALARQPDLRSRPQALRMTLAAAGAVFLIVWASLAVHYSHLDDVLALLFAALAI
                     RAVLADVPALAGLSLGLAVDAKPWALVFLPLALAVARDRRRHVAFYAVAVVLLAWLPFV
                     VADPATLGATQYHIVNEPSSALRALGVSAAGTPSWDRPAQLVLGCVLGAAAILRGRWVA
                     VPLLGIGARLLLDPGVYDYYSAGFLLGTLLWEALGLRRPVPVWSLVSFGALYLAPRLTN
                     DAQILGDLRLWLVLGVTLSVLLAPRDWCVASKPNEVAAGALRLPPRDPWVAHSVGAEAG
                     RWTVHH"
     misc_feature    complement(4417..4432)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.82"
                     /tool="antismash"
     misc_feature    complement(4473..4487)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     misc_feature    4474..4488
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     gene            4594..5763
                     /locus_tag="FNV64_RS10275"
                     /old_locus_tag="FNV64_10465"
     CDS             4594..5763
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373328.1"
                     /locus_tag="FNV64_RS10275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10465"
                     /product="glycoside hydrolase family 64 protein"
                     /protein_id="WP_240363651.1"
                     /transl_table=11
                     /translation="MAVAAATATTALLTFGAPSDANAAVPATIPLKFTNNSGRSEPVYI
                     YDLGTLLSTGQQGWADANGTFHAWPAGGNPPTPAPDASIAGPANGQSMTIRMPKFSGRI
                     YFSYGQKLDFRLTTGGLVQPAVQNPSDPNHNILFNWSEYTLNDSGLWINSTQVDMFSAP
                     YAVGVQLADGSTKNTGHLKTGGYTGFFNALRGQPGGWANLIQTRSDGTVLRALAPGHGI
                     EAGALPGTVMDDYVNRVWQKYSSSTLTVTPFTDQPNTKYFGRVSGDVMNFTNSAGAVVT
                     SFQKPDSDSIFGCYKRLDAPNDLVRGPISRTLCAGFNRSTLLTNPNQPDTSSASFYQDT
                     VTNQYARKIHAQMADGKAYAFAFDDVGNYESLVHDGNPQQAYVTLDPFN"
     gene            complement(5778..6443)
                     /locus_tag="FNV64_RS10280"
                     /old_locus_tag="FNV64_10470"
     CDS             complement(5778..6443)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127583.1"
                     /locus_tag="FNV64_RS10280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10470"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_060897528.1"
                     /transl_table=11
                     /translation="MSTPLPPFPRGQEPSGAPVPLELTVGPAAPQLRADAARNRARLLE
                     AATRLVEEHGVANVTMEAVAAAASVGKGTVFRRFGDRTGLLMALLDHTEQQFQAAFLSG
                     PPPLGPGAAPADRLHAFGCRVLREIHDRLDLYLAAEPDASRRFSSAPYRVRFTHVVMLL
                     REAVPGADGVLLAQTLMGYLEPALIHHLTRQCGMPLERLESGWHDLVKRTTCPVPDRP"
     gene            6571..7134
                     /locus_tag="FNV64_RS10285"
                     /old_locus_tag="FNV64_10475"
     CDS             6571..7134
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117016.1"
                     /locus_tag="FNV64_RS10285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10475"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_054236861.1"
                     /transl_table=11
                     /translation="MSVRILALVGSLRAGSHNRQLAEAAIKLAPEGAEIELFEGLAEVP
                     FYNEDLDVEGKVPAAATALREAAGRADAFLLFSPEYNGTITAVLKNAIDWLSRPYGASA
                     FTGKPAAVVGTAFGQFGGVWAQDEARKALGIAGAAVLEDLKLSVPGSVTRFAETHPVDD
                     AEVAAQLTEVVARLHSQVGTASAS"
     gene            7269..7946
                     /locus_tag="FNV64_RS10290"
                     /old_locus_tag="FNV64_10480"
     CDS             7269..7946
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433207.1"
                     /locus_tag="FNV64_RS10290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10480"
                     /product="AIM24 family protein"
                     /protein_id="WP_143654469.1"
                     /transl_table=11
                     /translation="MKGDLFSSDHMVQPAVTPGMTIQNAKSIKYAVNGDMLARQGAMIA
                     YRGNLQFERKGQGVGGMLKRAVTGEGLPLMTVRGQGEAWFAHEAQNCFIIGIEPGDLFT
                     VNGRNVLCFDSTLSYEIKTVKGAGVTGGGIFNSVFSGHGSLGLICEGNPLVIPVSPQQP
                     VYVDTDAVVGWTAQLHTSLHRSQSIGSMIRGGSGEAVQLKLEGDGLVIVRPSEATPQKA
                     QQH"
     gene            complement(8024..9799)
                     /locus_tag="FNV64_RS10295"
                     /old_locus_tag="FNV64_10485"
     CDS             complement(8024..9799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982566.1"
                     /locus_tag="FNV64_RS10295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10485"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_097283177.1"
                     /transl_table=11
                     /translation="MRRPHIRRVAIAVAVTTAATLPMAPAFAAPDSPARAATSASSPVE
                     AARAAAFAHASATGVGPGDTLRATDVMTDPDGKQHVRFVRSHQGLPVLGGDLVVHLGKQ
                     SAYLGVTRAADHAVKPATTEAKLTPQQAEQKAAAVAQGDAGSAELVVDARDGAAALAYQ
                     VRVTDSDTTEAGGSRTVVVDAQSGRIRSNTPDSDEFISPHLEETLREKGETASPVTGVA
                     TQPAGLLGATTAARYPVTATGSGTSLFAGKVTLTTTRTARTSFLLKDPTRWNTETRDAK
                     GAELEAFSRGTKFTSTTNKWGTGTTANRTTAAVDAQYGITQTLDFYKKTFGRKGIKNNS
                     TGARAMVHFGRKVGNAFWDSTCGCMLYGDGDGAMFKKPLVVLDVTGHELTHGVVDATAA
                     LEPTRVDARGNQYGEPGALNESLADIFGSNVEFSANNPKNPPNYLMGEKLGLAQKFLRR
                     LDHPSLDKLEGTIDYWSPAAYDTEVHAGSGVSSHAYYLLAEGSGRKTIGGVKYDSPTFD
                     GSRVTGIGRAKATAIFYRALTRYMVSTTDFHDARTATLEAAADMYGATSAEYQAVDAAW
                     AAVNVTTANTPAVGR"
     misc_feature    complement(9943..9958)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(10001..11056)
                     /locus_tag="FNV64_RS10300"
                     /old_locus_tag="FNV64_10490"
     CDS             complement(10001..11056)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670760.1"
                     /locus_tag="FNV64_RS10300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10490"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_143600424.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-63, bitscore:
                     212.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPRTVLTAPPAAPEILARCRELVAPALAEAVDGLHPWVAEMAG
                     YALGRCEVGGAPATHRQGKGVRQALAVLGAEAAGGSAEAGVPGAVAVELLHTFSLLHDD
                     IMDGDALRRGRPAVWKAYGTGPAVLTGDALFALAVETLTAAPATSHAAAAVRRLTRASR
                     DLVRGQADDLLFAHRPWTGPDAVSAGEYEAMAEHKTGALLGCALALGAGLAGAPRETAA
                     ALDRAGRHLGVAFQIADDLLGIWGDPAVTGKPVHGDLRQGKKTLPVLAALAAPDRSPLA
                     ELLASTAVLDDGAVRRAATLVERAGGRTAALGAARRHLTAADTLLAGASLAPRPAADLR
                     TLLSSLAHRTI"
     gene            complement(11053..12111)
                     /locus_tag="FNV64_RS10305"
                     /old_locus_tag="FNV64_10495"
     CDS             complement(11053..12111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982568.1"
                     /locus_tag="FNV64_RS10305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10495"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_143607188.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYQGALTTLSVNSSLTDVLAAGTEQLRAAERVGARAE
                     AARSGLAVAEAHRRLGQVADADRAWKASYRTAREARDTGAMAWALWSGGTLARQRGAFP
                     LAWRLLRLAAELGEQSGDVVVRGYSLAGMAETGRIQGDYAAVTALHEQLLAEARRRGEA
                     RHTVWALEGIAQIHRNTGAYDTAYALFEEAAEIAARAEDRRGHAWALRGLADIVSVRDR
                     DPDRALALLSEAEVSCRAMNLSGALAYNHKMRGNVLYRAGRYERARDLYTRALAEFEAM
                     SEPRGRALSRLGLVKSLARLGRDHAETAAELTELARVLEGIGLRHAQEMVERARTELGL
                     TPPEGADPEAAR"
     cand_cluster    11560..21970
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    11560..21970
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[16559:16970](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16560..16970
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            12417..13301
                     /locus_tag="FNV64_RS10310"
                     /old_locus_tag="FNV64_10500"
     CDS             12417..13301
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892332.1"
                     /locus_tag="FNV64_RS10310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10500"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_097283180.1"
                     /sec_met_domain="APH (E-value: 4.5e-30, bitscore: 104.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPGEFPIDASLVRRLLAAQFPRWAELPLKRFPSAGTVNALYRLG
                     DDLAVRLPRIEGGAEDVAREAHWVPRLAPLLPAAVPEILATGTPGEGYPWPWMVQRWLD
                     GEPPRAGRLSDPLPLAADLGAFVAALRRVRLPDGPTAYRGVPLSTADAMTRAALDELRG
                     TIDTSAATAAWEAALAAPAWTGPPTWAHSDLMPGNLLTRGDRLDAVLDFGTVGVGDPAC
                     DLIPAWNLFPAEARDTFRRAAGADDAAWARGRGWALSMALIQLPYYRVTNPVIAANAEH
                     VIHAVLTEADARP"
     misc_feature    complement(13310..13324)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(13310..13325)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(13311..13324)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.35"
                     /tool="antismash"
     gene            13346..13972
                     /locus_tag="FNV64_RS10315"
                     /old_locus_tag="FNV64_10505"
     CDS             13346..13972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526757.1"
                     /locus_tag="FNV64_RS10315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10505"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_099939509.1"
                     /transl_table=11
                     /translation="MSTHLQGSLFDQTDELHLSQLNATRRTVLGDGAWIDLLPGWLSGA
                     DALFARLVDEVPWRAERRQMYEHVVDVPRLLAYYRAGDALPHPILDEARQALSAHYARE
                     LGEPFTTAGLCYYRDGRDSVAWHGDRIGRGAREDTMVAILSVGAPRDLLLRPRRGGETV
                     RRPLGHGDLIVMGGSCQRTWEHAIPKTARAAGPRISVQFRPDGVN"
     gene            complement(14012..14611)
                     /locus_tag="FNV64_RS10320"
                     /old_locus_tag="FNV64_10510"
     CDS             complement(14012..14611)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138616.1"
                     /locus_tag="FNV64_RS10320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10510"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_054236854.1"
                     /transl_table=11
                     /translation="MSTVSTPPPGLSASPIAPPRRDAEATKAAILRAARHLMARHAHAD
                     ITLKAIADRAGVSAPLILKYFGNKDALFGRVMSFETDAAALLDAPLDQLGPHMVRQVLV
                     GQTERGADPVLRIIFAPRQGDQGDVMRANFRTQVSDRLALRLSGPDADLRAELAVGTLL
                     GLGAMYGIARGTRLRATAIEDIVDRYGPTVQALLTP"
     gene            complement(14608..16053)
                     /locus_tag="FNV64_RS10325"
                     /old_locus_tag="FNV64_10515"
     CDS             complement(14608..16053)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670769.1"
                     /locus_tag="FNV64_RS10325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10515"
                     /product="MFS transporter"
                     /protein_id="WP_143654470.1"
                     /transl_table=11
                     /translation="MVALRDRLTVPVLALGGSLMAVMQVVVVPLLPDLPRLTGASAGAV
                     SWMVTATLLTGAVLNPVLGRAGDMYGKKKVLLIALGMMTVGSLMCALTSDIRILIAARA
                     LQGAAAAVVPLSISLLRDELPPERTGSAVALMSSTVGIGAALGLPIAAIVVQYASWHVM
                     FWGTTAVGALGTALAWWAVRESPVREPGRFDMTGALGLALGLSCLLLGVSQGGQWGWSS
                     PRIIGLFVGSVCVLGLWWAQQLRAARPLVDLKLATSPRVALPHVAALLTGFAFYANSLV
                     TAQLVQAPKATGYGLELSIVATGLVLLPGGVIMLLLSPVSARISAARGARVTLALGTLV
                     IAAGYGIRIINSHSLLVILLGSAVCAMGTAFSYSALPTLILRAVPAGQTASANGVNVLM
                     RTVGQAVSSAAVAAILVHHTSLVGGAPIPTLHGYLLAFAMAGTVALVACVAALVIPADP
                     TLRDTRRASGSSDAPRDEAFEGA"
     gene            16560..16970
                     /locus_tag="FNV64_RS10330"
                     /old_locus_tag="FNV64_10520"
     CDS             16560..16970
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038019.1"
                     /locus_tag="FNV64_RS10330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10520"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_143654471.1"
                     /sec_met_domain="melC (E-value: 5.3e-47, bitscore: 158.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELTRRRALGAAAALAAAAGTQTVAVARAADTGHHVGPEAFDEV
                     YRGRRITGRAAGGGHHHEHGAGYAVFVDGVELHVMQNADGSWISVVSHYDPVPTPRAAA
                     RAAVVELQGAPLVPLGMPMPMPMPMPMPMPQQ"
     gene            17005..17829
                     /locus_tag="FNV64_RS10335"
                     /old_locus_tag="FNV64_10525"
     CDS             17005..17829
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982575.1"
                     /locus_tag="FNV64_RS10335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10525"
                     /product="tyrosinase family protein"
                     /protein_id="WP_143607192.1"
                     /transl_table=11
                     /translation="MTVRKNQANLTADEKRRFTDALLQLKRSGRYDAFVTTHNAFILGD
                     TDNGERTGHRSPSFLPWHRRFLLEFERALQSVDASVALPYWDWSTDRSPRSTLWAPDFL
                     GGTGRSLDGRVMDGPFAASAGNWPISVRVDGRTYLRRSLGSGTRELPTRAEVDSVLGMA
                     TYDMAPWNSSSDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYIDKL
                     WADWQRRHPASGYLPLSGTPDVVDLDETMKPWNDVKPAELLDHTAFYTFDTV"
     gene            complement(17863..18582)
                     /locus_tag="FNV64_RS10340"
                     /old_locus_tag="FNV64_10530"
     CDS             complement(17863..18582)
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987922.1"
                     /locus_tag="FNV64_RS10340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10530"
                     /product="ribonuclease H"
                     /protein_id="WP_082417821.1"
                     /transl_table=11
                     /translation="MIGDMLERVVAACDGASKGNPGPAGWAWVVADGAETPTRWEAGAL
                     GTATNNVAELTALERLLTAIAPDVPLEIRMDSQYAMKAVTTWLPGWKRKGWKTASGKPV
                     ANQELVARIDELLDGRTVEFRYVPAHQVDGDRLNDFADRAASQAAIAQQPAGSDLGSPE
                     PPPSPDTPAPSGAGRRRTTATASAKTPRQGTSARTIKAKFPGRCLCGRSYAAGEPIAKN
                     GQGWGHPECRTAEPSNA"
     gene            complement(18563..19618)
                     /locus_tag="FNV64_RS10345"
                     /old_locus_tag="FNV64_10535"
     CDS             complement(18563..19618)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015033489.1"
                     /locus_tag="FNV64_RS10345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10535"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_063818272.1"
                     /transl_table=11
                     /translation="MLRIHFTSDDLQNIRVARQPDPLWELMCSVCRLETGQGPLEFGHW
                     RRSARQRFSGDSNLVRALRPLRALIPATGYIPDFLTPPVTGGGLSAGLDQLLRTPRGQL
                     VRELSRLAESRPVPNWAASLGRPGSDALKVLANSLGIYFRGLLEPHWPHIRTAVGNDVG
                     VRARALLDGGTQALLESLRPVARWSAPVLEVDYPVQRDLYLEGRGLLLVPSYFCWRRPT
                     ALADPGLDPVLVYPVAKTPLAVADGTDGGVERLLGRTRAAVLTEVAGQSARTTSEVAEA
                     VGIALPSASYQIGVLRDGGLVASLRDGKYVLHTATLLGLRLLGTSPRMRESALRPVRGA
                     AAGPWHDRGHA"
     misc_feature    complement(19577..19591)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.76"
                     /tool="antismash"
     gene            complement(19795..20592)
                     /locus_tag="FNV64_RS10350"
                     /old_locus_tag="FNV64_10540"
     CDS             complement(19795..20592)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031563.1"
                     /locus_tag="FNV64_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10540"
                     /product="VOC family protein"
                     /protein_id="WP_143600439.1"
                     /transl_table=11
                     /translation="MAVQPEGTPCWADAMFSDVEGAKSFYGDVLGWTFGESSSEYGNYT
                     QAYANGKAVAAVVPPMPGQEGQSAWCLYLASPDAAATAQKIRADGGEVLMEPMQVGDFG
                     TMVIARDPSGVVFGVWQPGRHEGFEARGVPGAYCWAEVFTREPEKSDTFFSAVFGYRMK
                     QLDDDAVDFRLYDLGKDPVLGRMRMTDDFPPEVPPYFNVYFTVEDCDAAVAKATERGAI
                     LRFGPMSSPFGRFAALSDPQGAAFSVIDVKTTEGAMPKATDVS"
     misc_feature    complement(20622..20635)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     gene            20747..21763
                     /locus_tag="FNV64_RS10355"
                     /old_locus_tag="FNV64_10545"
     CDS             20747..21763
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0004024 - alcohol dehydrogenase (NAD+)
                     activity, zinc-dependent [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008746774.1"
                     /locus_tag="FNV64_RS10355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_10545"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_143656986.1"
                     /sec_met_domain="ADH_N (E-value: 2e-29, bitscore: 100.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAWEVARPGPVEGEPLRFVERPIPVPAADELLVHVRACGVCRTD
                     LHVTEGDLPVRRAQVTPGHEVVGVVAATGGDVLDHAVGDRVGVAWLHRTDGTCGYCARG
                     SENLCPASEYTGWDADGGYAEYTTVPAAFAYRLPGEVDDVALAPLLCAGIIGYRALLRA
                     ALPDAGRLGLYGFGGSAHLCAQLALAQGATVHVLTRDPAARRLALELGAASARGAYDEP
                     PEPLDSAILFAPVGDLVPVALRALDRGGILSVAGIHLSDTPPLRYESDLFYEKELRSVT
                     SNTRRDGRDFLALAARHGVRATTHAYPLSEAQRALRDLKAGRFDGAAVLVNDFPART"
ORIGIN
        1 cccaggtgat gaccaccgag accagggcga gttggacggc cgcgcggaag ccggcgagga
       61 ggatctcccg ggcccggctc ttgtacgggt gcggatcgag acgggcccag cccgcgaccg
      121 ccgccgccac caacagcaga acggcgagca ggacgccgag ggttgggttg accggtacaa
      181 gagatgccgc actcgacctc acgttttccg cctcaagaag ctgccgcacg ggccgatggg
      241 gtgcgcgggt ccccaacctg actggccccg acggccgaca gcgcagtcta cggtgccgca
      301 gggccgggac cgggcaccgg tctcgcgctc gctgcgcacg accgcgctgg ccgccctgcc
      361 ctccgccgtc ctcgcagcgg tccactacgc ccccgtcgtc tccacgttcg ggccgctgcg
      421 cgaccgcacc atgcctcgcc tgtccggccg ggcccacgcg gaccgcatcg tcctcaacgt
      481 cgacgccgga cccgacccgc tgtccacccc gttcttccgc gactgctcga cgggcgcggg
      541 gtgcgcgcca ccttcttcct gctgagcagc gcggcacacc gctcccccgg cgcaccgcac
      601 ggtgaccgcg gacctcgacg gcggcggcac tatcctgctg cacgattcgg accgcacctc
      661 ggcgcctggc gctcggcgcg ctcccccgcg tcctcgacac ctgcacgcag cgaggccacg
      721 aggtcggccc gctctgcgac cacggacagc cggtgccgga cacgagctgc gggaaccccc
      781 tgcggccacc tatcgtctac agctatgtag acgataggct ctgccgtagt cgttcattcc
      841 tgtgtgctca ccgacgtcag ggcacgaccg ctcgccggat gcacctcgcg ttggagtccg
      901 acccggaccc cgaggcggtg ctcgcccggt tcattgacag gctgcccgcc acggacgaag
      961 agttgctgcg gcaaccactg ggcaatctgc cggaggagcg gtgagcggcg atgcgggggc
     1021 ggccgtggtg ctcgacagcg gcgagagcac ccacaagttc gcgggcaaga tcgtcatggc
     1081 agcccttgcc gcgaactgaa gcaacacccc ggagagtgac tttgacgacc aaccacaatg
     1141 ggtggacttt gcgtctcgcg gccccgatgc ggagactccc cccgcggaag ccgatggtcg
     1201 tcgaccggcc gacaccgcgc ccagcggtgt ggatggccgg ggccgggatc gcactgttcg
     1261 ctctggtcgg cgcgagcgcg cccaaccaca acacgctcag ggcaccgatc ccctggctcc
     1321 ggctgcctgc catggccggc accgtctccc agacggccac gatcgcggcc atcgtgctgt
     1381 cgtgctgggg cacgctgggc atgctcaagg cccatgagcg gggctggaga cccgatgccc
     1441 ggctcctgtt ccggctcggc gccatgaccg cgctcgccgt cgccaacctc accccggtcg
     1501 gctcctccga cacggccagc tacgccgcgt acggccgtat cgccgcgctc ggcggtgacc
     1561 cgtacgtgac gactcccgcc cggctgggcg gcgcgtacgc ccacctggtg agcgaggcgt
     1621 ggcggaacac cccttccgtg tacgggccgg tggcgacgtg gtggcagggc gccgcggcgt
     1681 tcatcggtca ggagcggccg tggctgacca tttgggcgct gatgctcgcg aacgccgccg
     1741 tcttcgtggg taccgggtac ctgctgctgc ggaccgccga cgatccggtc cgtgcgggcc
     1801 tggtgtggag cgtcaatccg ctgctgatcg gtgtgctggt cgagggtggg cacctggaca
     1861 ccctcgtcgc gggcctggcc gtctgcgccg ttcacctagc ccgcaggacg acccggtggc
     1921 accacgacct gatcgtggga gggctggtcg gccttgcctg cggtgtgaag atcagtgcct
     1981 gcctgttcgg tgtcgggctg gcctggcctc tgctgcgttc gggccgctgg cgaccggccg
     2041 cccggcaggc atgcgcggcc gcgctgaccc tggccgcgct ctacggagcc tacggagcgc
     2101 acgcgctggt gccgctctcc gcggcctccc aactggtctc cgcaccctcc gtctgggcgg
     2161 tcttcgacca gtgcgccacg gcggtcctcg gccctggttc gaccgcggcg atcgtcagcg
     2221 tgctgtggcc ggtggtgatg ctcgcgctgg cgtgggtgct acgccgccgc gccgctccgg
     2281 acgccccctc cgtcatcgcc gtgccgttcg cgctggcctt cgcctgggtc ctcgcggcac
     2341 cgtggtcgat gccgtggtac acggctctcg cctgggccct gacggccctg ttcagccagg
     2401 gccgcccgac ccagtacctc accgtggcca ccgccgtcct ggccctgtcc cacaacagcg
     2461 gcggccacgg ctggacatgg tgagagacca cgccgggccg accgcagagg tgtttcagac
     2521 gcttcgcacc tgaatctcat ggttgtgcag gaacccggga gcggtcaggg gactctttcc
     2581 aggcaggggg tcgaccacca gagaggcatg aggatggctg atcagagcag ccgccccgcg
     2641 cggagcgggg ccgcctggca ctggtggttc ctcggactct gggcgacggt ctggttcctg
     2701 gcggacctgc acggcggcgg ctactcgtgg cactacttcg cgaacggcag caccttgctg
     2761 ttctccggct ccggggcctc gccggcgggg ggcctgcacc tctatgcgaa ctacccgaac
     2821 ctgcagatag gaccggcggc ctttctctgc gcctgggttc tggggaacct cggcggggtc
     2881 gtcgccgccc agctgacgat gatgggcgtc ggccttctgg tgctgcggct gatcgagcag
     2941 acggcactgg cccggcagcc ggatctgcgg tcgcgcccgc aggccctgcg gatgaccctc
     3001 gcggccgccg gtgcggtgtt cctgatcgtc tgggcatcgc tggcggtgca ctacagccac
     3061 ctcgacgacg tgctggcgct gctcttcgcg gcgctggcga tccgggcggt cctcgctgac
     3121 gtcccggcac tggcgggact gagcctgggc ctggccgtgg acgccaagcc gtgggctctg
     3181 gtcttcctgc cgctggctct cgccgtggcc cgcgaccgac gacggcatgt cgcgttctac
     3241 gccgtcgccg tcgtgctgct ggcctggctg cccttcgtcg tcgccgaccc cgcgacgctg
     3301 ggtgcgaccc agtaccacat cgtcaacgag ccgtcctcgg cgctgcgcgc gctcggggtg
     3361 tcggcggcgg ggacgccgtc gtgggaccgg ccggcgcaac tcgtgctcgg ctgcgtgctt
     3421 ggggcggccg cgatcctccg ggggcgctgg gtggcggtgc cgctgctcgg catcggcgcg
     3481 cgactcctgc tggatcccgg cgtctacgac tactactcgg cgggattcct gctcggcacc
     3541 ttgctctggg aggccctggg gctgcgtcgg cccgtgcccg tctggtcgct ggtctccttc
     3601 ggcgccctgt acctcgcccc gaggctgacc aacgacgcgc agatcctggg cgacctccga
     3661 ctctggctgg ttctcggggt gaccctcagc gtcctgctgg ctccacggga ctggtgcgtc
     3721 gcgtcgaaac cgaacgaggt cgccgccggc gccctccgac tgcctccccg agacccgtgg
     3781 gtcgcccact cggtcggcgc ggaagcgggc aggtggaccg tgcatcactg agcgtgactg
     3841 tcgcgagccc ggacacaggc tctgtaacta ccgcgtcgtt gccagggaaa gtcgcgctgg
     3901 tgacggggcg accagcggca ccggggcagc cgccgcggaa acgcacgccg agtgcgacac
     3961 gcacgtactg gtggcgagcc ggggccgagg ccgcggcggg gccgtcgtcg aggccgtccg
     4021 gcaacacggt ggcacggcgg acttcgtggt tgccgacctg ctggacgccg actcggcgcg
     4081 acgccgcggc ccccttacat ttccggctgc atcaacaggt acgagcaggc aacggccgaa
     4141 aggccataca cccagctcag tgacccgaca cgctccagcg atactcgccg gagcgccgtc
     4201 aacggccccc atccacctcc ccgcagcggt tcccctccgt ccagcccttc cggccgtcgc
     4261 cgatgccctg ccgggaacgc ccgatgcggt tcgcgacgag agccgcgcgg ccgtcgagga
     4321 caccacagcc gcgccccacc ggcattcgtg accgcttccg ccgaccaccc gtcggatccg
     4381 ccgtggacat caccatgtgc cgccgcccca ggccaagttg gaccagacca atcctgtccg
     4441 aatcgttgac atgtacggca cccgccgcaa ttctgagagc gctctcaacg agaaccggac
     4501 ggctccactc cgccggaatc cacctcgttg gaatcccccc acccaaggag agagcgagtg
     4561 cccagaaggc tcaggagtct caaatggcat gccctggcgg tggctgcggc caccgccacc
     4621 acggcgcttc tcacgttcgg cgccccctcc gacgcgaacg cggccgtccc ggcgacgatc
     4681 ccactcaagt tcaccaacaa ctccggccgc agcgaacccg tgtacatcta cgacctcgga
     4741 acactcctct cgacgggcca gcagggctgg gccgacgcga acggcacgtt ccacgcctgg
     4801 ccggccggcg gcaacccgcc gacgcccgcg cccgacgcct cgatcgcggg accggccaac
     4861 ggccagtcga tgacgatccg gatgcccaag ttctccggcc ggatctactt ctcctacggc
     4921 cagaaactcg acttccgcct gaccaccggc ggcctggtgc agccggccgt gcagaacccg
     4981 agcgacccca accacaacat cctcttcaac tggtccgagt acacgctcaa cgactccgga
     5041 ctgtggatca acagcaccca ggtcgacatg ttctcggccc cgtacgccgt cggggtccag
     5101 ctcgccgacg ggagcaccaa gaacaccggc cacctcaaga cgggcggcta caccgggttc
     5161 ttcaacgccc tgcgcggcca gcccggcggc tgggccaatc tgatccagac ccggtccgac
     5221 ggcaccgtcc tgcgggcgct ggctcccggc cacggcatcg aggcgggcgc gctgccgggc
     5281 accgtcatgg acgactacgt caaccgcgtg tggcagaagt acagttcgtc gacgctgacc
     5341 gtgacaccgt tcaccgatca gccgaacacg aagtacttcg ggcgggtctc cggtgacgtc
     5401 atgaacttca ccaacagcgc cggagccgtc gtcaccagct tccagaagcc cgactcggac
     5461 agcatcttcg gttgctacaa gcggctggac gccccgaacg acctggtacg cggccccatt
     5521 tcacggaccc tgtgcgcggg cttcaaccgc tcgacccttc tcaccaaccc caaccagccg
     5581 gacacgagct cggcgagctt ctaccaggac acggtgacca accagtacgc ccgcaagatc
     5641 cacgcgcaga tggccgacgg caaggcctac gcgttcgcct tcgacgacgt gggcaactac
     5701 gagtccctcg tccacgacgg caacccccag caggcgtacg tcacgctgga cccgttcaac
     5761 tgacggaaac cgaagggcta gggcctgtcc ggcaccgggc aggtggtccg cttcacgagg
     5821 tcgtgccagc cggactccag gcgttcgagc ggcatcccgc actgtcgcgt caggtggtgg
     5881 atcagggcgg gttccaggta gcccatgagg gtctgggcga ggagaacgcc gtccgcgccg
     5941 ggcacggcct cgcgcagcag catgacgacg tgggtgaagc ggacccggta aggggcggag
     6001 ctgaagcggc gggaggcgtc cggctcggcg gcgaggtaca ggtcgagccg gtcgtggatc
     6061 tcgcgcagga cccggcagcc gaaggcgtgc aggcggtccg ccggggccgc gccggggccg
     6121 agaggtggcg ggccgctgag gaaggcggcc tggaactgct gctcggtgtg gtcgagcagg
     6181 gccatcagca ggccggtgcg gtcaccgaag cgccggaaga cggttccctt gcccaccgag
     6241 gccgcggcgg cgacggcctc catcgtcaca ttggcgaccc cgtgctcctc caccagccgg
     6301 gtggcggcct ccagcagccg ggcgcggttg cgcgcggcat cggcgcggag ctgcggcgcg
     6361 gcgggcccga cggtcagctc cagcgggacc ggggctcccg agggttcctg ccccctcggg
     6421 aagggcggaa gtggggtgga catgaacaca gcgtaacggc agaagggggc aactggaccc
     6481 tggtccgttt aggtgctaca acattaaaca gaccagcaag cggacctcgg tccgttttat
     6541 tgccgcaatg tttcgtcccc gggagttccc atgtccgtac gcatcctcgc gctcgtcggc
     6601 agccttcgcg ccggctccca caaccgccag ctcgcggagg cggccatcaa gctcgccccc
     6661 gagggcgcgg agatcgagct gttcgaggga ctcgccgagg tccccttcta caacgaggac
     6721 ctcgacgtcg agggcaaggt cccggccgcc gccaccgccc tgcgtgaggc cgcgggccgt
     6781 gccgacgcct tcctgctctt ctcgccggag tacaacggca cgatcacggc cgtcctgaag
     6841 aacgccatcg actggctgtc gcgtccgtac ggcgccagcg ccttcaccgg caagcccgcc
     6901 gccgtggtcg gcaccgcgtt cggtcagttc ggtggcgtct gggcgcagga cgaggcccgc
     6961 aaggccctgg gcatcgcggg tgccgccgtc ctggaggacc tcaagctctc cgttcccggc
     7021 tccgtgaccc gcttcgccga gacccacccg gtcgacgacg ccgaggtcgc cgcccagctc
     7081 accgaggtcg tcgcccgcct gcacagccag gtcggcaccg ccagcgcctc ctgacgactc
     7141 cccccagggc cggtccggtg ccaccggacc ggcccttcgc gcgttcccgg cagccgccga
     7201 ccacccccaa ccgtccccgg atgtcggcga tcttggcgga accaaaccct ccgggccaag
     7261 atgcccgcat gaagggtgat ctcttttcca gtgaccacat ggtgcagccc gccgtcacgc
     7321 cgggcatgac catccagaac gccaagtcga tcaagtacgc cgtcaacggc gacatgctcg
     7381 cgcgccaggg ggcgatgatc gcctaccggg ggaatctgca gttcgagcgc aagggccagg
     7441 gcgtgggcgg catgctcaag cgggcggtca ccggtgaggg actgccgctg atgacggtgc
     7501 gcgggcaggg cgaggcctgg ttcgcgcacg aggcgcagaa ctgtttcatc atcggcatcg
     7561 agccgggcga cctgttcacc gtgaacgggc gcaacgtcct gtgcttcgac tccacgctgt
     7621 cgtacgagat aaagaccgtg aagggcgcgg gcgtcaccgg cggcggcatc ttcaacagcg
     7681 tcttcagcgg tcacggcagt ctggggctga tctgcgaagg caacccgctg gtgatacccg
     7741 tctcgccgca gcagccggtg tacgtcgaca cggacgcggt cgtcggctgg accgcgcagc
     7801 tccacacctc gctgcaccgc tcgcagtcga tcggttcgat gatccgcggc ggctcgggcg
     7861 aggccgtgca gctgaagctg gagggggacg gactggtcat cgtacggccg agtgaggcga
     7921 ctccgcagaa ggcacagcag cactgacgcc gaagggaaac ggcgaaaggg gccccgccag
     7981 tggcggggcc cctcttctcg tgccgtcctt ctcgtgccgt ccgtcagcgg ccgacggccg
     8041 gggtgttggc ggtggtcaca ttgacggcgg cccacgccgc gtccaccgcc tggtactcgg
     8101 cgctggtcgc cccgtacatg tcggcggcgg cctcgagggt cgcggtccgc gcgtcgtgga
     8161 agtcggtcgt ggagaccatg tagcgggtga gcgcgcggta gaagatcgcg gtcgccttgg
     8221 cgcgtccgat gccggtcacc cgcgagccgt cgaacgtcgg cgagtcgtac ttcaccccgc
     8281 cgatcgtctt gcggccactg ccctcggcga gcaggtagta cgcgtgcgag gagacgccgg
     8341 agccggcgtg cacctcggtg tcgtacgccg cgggcgacca gtagtcgatg gtgccctcca
     8401 gcttgtccag ggaggggtgg tcgaggcggc gcaggaactt ctgggcgagg cccagcttct
     8461 cgcccatgag gtagttgggc gggttcttcg ggttgttggc ggagaactcg acgttggacc
     8521 cgaagatgtc ggcgagggac tcgttgagcg cgcccggctc gccgtactgg ttgccgcgcg
     8581 cgtccacccg ggtgggttcg agggcggcgg tggcgtcgac gacgccgtgg gtcagctcgt
     8641 ggccggtgac gtccaggacg accagcggct tcttgaacat ggcgccgtca ccgtcgccgt
     8701 agagcatgca gccgcacgtc gagtcccaga aggcgttgcc caccttgcgg ccgaagtgga
     8761 ccatcgcgcg ggcgccggtg ctgttgttct tgatgccctt gcggccgaag gtcttcttgt
     8821 agaagtccag ggtctgggtg atgccgtact gggcgtcgac cgcggcggtg gtccggttgg
     8881 cggtggtgcc cgtgccccac ttgttggtgg tgctggtgaa cttcgtgccg cgcgagaagg
     8941 cctccagttc cgcgcccttg gcgtcccggg tctcggtgtt ccagcgggtg gggtccttga
     9001 ggaggaagct ggtccgcgcg gtccgggtcg tggtcagcgt caccttgccg gcgaagaggg
     9061 aggtgccgct gccggtggcc gtgaccgggt agcgggcggc cgtcgtcgcg ccgaggaggc
     9121 cggcgggctg ggtggccacg cccgtcaccg ggctcgccgt ctcgcccttc tcgcgcagcg
     9181 tctcctccag gtgcggcgag atgaactcgt cgctgtcggg ggtgttgctg cggatccggc
     9241 cgctctgcgc gtccacgacg accgtgcggg agccaccggc ctcggtggtg tcgctgtcgg
     9301 tcacgcgcac ctggtaggcg agggcggcgg cgccgtcgcg ggcgtcgacg acgagttcgg
     9361 cgctgcccgc gtcgccctgg gcgaccgcgg cggccttctg ttcggcctgc tggggcgtca
     9421 gcttagcctc ggtcgtggcc ggcttgacgg cgtggtcggc ggcccgggtc acgcccaggt
     9481 aggcggactg cttgccgagg tggacgacga ggtcgccacc gagcaccggg agcccttggt
     9541 ggctgcggac gaagcggacg tgctgcttgc cgtccgggtc cgtcatgacg tccgtggccc
     9601 gcagggtgtc acccgggccg acaccggtgg ccgaggcgtg ggcgaacgcg gcggcccggg
     9661 cggcctccac cggcgaggag gccgaagtcg cggcgcgggc gggcgagtcg ggcgccgcga
     9721 aggcgggggc catcggaagc gtggccgccg tcgtcaccgc gacggcgatc gccacgcggc
     9781 gtatgtgggg tctacgcact gagttccttc gaacgggggc ggccggcgtc gccaaccgcc
     9841 ctgagacacg gcgccgttga acgccgtgga ggctgtcggg ccctcccgac agatgcgacg
     9901 ggaggggcgg tggttgcccg atgaggtcca ccaacccgca catgtgatcg aggtcgcagc
     9961 gcctccggcc cacagcgggg gagccggagg cgcgcaggtg tcagatcgtg cggtgggcga
    10021 gggaggagag gagcgtccgc aggtccgcgg cgggacgtgg ggccagggag gctcccgcca
    10081 gcagggtgtc cgccgcggtg agatgccggc gcgccgcgcc cagggccgcc gtgcgaccac
    10141 cggcgcgctc gaccagggtc gccgcccggc gtacggcgcc gtcgtcgagg acggcggtgg
    10201 aggcgaggag ttcggcgagc ggggagcggt ccggcgcggc cagggcggcg agaacgggga
    10261 gggtcttctt cccttgccgc agatcaccgt gcaccggctt cccggtgacg gccggatcgc
    10321 cccagatgcc gagcaggtcg tcggcgatct ggaaggccac cccgagatgc cgtccggcgc
    10381 ggtcgagggc ggcggcggtc tcccgcggcg cgcccgccag ccccgcaccg agggccagcg
    10441 cgcagccgag cagggcaccg gtcttgtgct ccgccatcgc ctcgtactcc cccgcgctca
    10501 ccgcgtcggg gccggtccac gggcggtggg cgaacagcag gtcgtcggcc tgaccccgga
    10561 ccagatcgcg cgaggccctc gtcaaccgcc gcacggccgc cgcggcgtgg gaggtcgcgg
    10621 gcgccgcggt gagggtctcg acggccaggg cgaagagcgc gtcgcccgtg aggacggcgg
    10681 ggccggtgcc gtacgccttc cacacggcgg gacggccgcg gcgcagcgcg tcgccgtcca
    10741 tgatgtcgtc gtgcaggagc gagaaggtgt gcagcagttc caccgccacc gcgcccggca
    10801 cgcccgcctc ggcggaaccg ccggccgcct cggccccgag tacggcgagt gcctgtcgta
    10861 cgcccttgcc ctggcggtgg gtcgcggggg ctccgccgac ctcgcagcgg cccagcgcgt
    10921 agccggccat ctccgccacc caggggtgca gtccgtcgac cgcctccgcg agggccgggg
    10981 cgaccagttc gcggcagcgc gccaggatct ccggggcggc gggcggcgcc gtcaggaccg
    11041 tacggggaga ggtcatcggg cggcctccgg gtccgcgccc tccggcgggg tgaggccgag
    11101 ttccgtccgc gcccgttcga ccatctcctg ggcgtgtcgc agcccgattc cctccaacac
    11161 gcgggccagt tcggtgagtt cggcggcggt ctcggcgtgg tcacggccga gcctggccag
    11221 ggacttgacc agtccgagcc gggacagcgc ccggccgcgc ggctcgctca tcgcctcgaa
    11281 ctccgccagt gcccgcgtgt agaggtcccg ggcccgctca taacgcccgg cccggtagag
    11341 gacgttgccg cgcatcttgt ggttgtaggc gagtgccccg gacaggttca tcgcccggca
    11401 ggacacctcc gcctcactca gcagtgccag cgcgcggtcc gggtcccggt cgcgtacgga
    11461 gacgatgtcc gcgaggccgc gcaaggccca ggcgtggccg cgccggtcct cggcgcgcgc
    11521 ggcgatctcg gccgcttcct cgaacagggc gtacgcggtg tcgtaggcgc cggtgttgcg
    11581 gtgtatctgc gcgatgccct ccagggccca cacggtgtgg cgggcctcgc cgcgcctgcg
    11641 ggcctcggcc agcagttgtt cgtgcagggc ggtcacggcc gcgtagtcgc cctggatccg
    11701 gccggtctcc gccatgcccg ccagggagta gccgcgtacg acgacgtccc cggactgctc
    11761 gccgagttcg gcggccagtc gcagcagccg ccaggccagc gggaacgccc cgcgctggcg
    11821 ggccagggtg ccgccgctcc acagcgccca cgccatcgcg ccggtgtccc gggcctcgcg
    11881 ggcggtgcgg tagctcgcct tccacgcccg gtcggcgtcg gccacctgcc cgagcctgcg
    11941 gtgcgcctcg gcgaccgcca ggcccgaccg ggccgcctcg gcacgggcgc ccacgcgctc
    12001 ggcggcgcgc agctgctcgg tacccgccgc caggacatcg gtcagcgagg agttcacgga
    12061 cagggtggtc aaagcgccct ggtactcggg ggcgaaggcc ttgccgtaca tggatccctt
    12121 tcgatcggct gactttcgcg gaccggcggc accccacgac tcgactccgc acccctcgta
    12181 tacacgctgt atatacacgc gttgtataca cggagcgtat agtgtgctgg atttccactc
    12241 gggaatccct gccgtttcgc ggttgtcgcg ccgcccatcc gttgtcgatc aagacggcga
    12301 cggcgtgcgc caggttgcct gtcgcgaaaa agaagcgcga acctccttca ccccaggcat
    12361 agttgggccg cgtgtcagac agagatccag aagcgcaaac gatccccgcg ggcccgatgc
    12421 gtcccggcga gttcccgatc gacgcctcgc tcgtgcgacg gctgctggcc gcgcagttcc
    12481 cacggtgggc cgagctgccc ctgaagcgct tcccgtcggc gggtaccgtc aacgccctgt
    12541 accggctcgg cgacgacctg gccgtacgcc tcccccggat cgaggggggc gccgaggacg
    12601 tggccaggga agcgcactgg gtgccgcggc tcgccccgct gctcccggcc gccgtccccg
    12661 agatcctcgc caccggcaca cccggcgagg gctacccgtg gccctggatg gtgcagcgct
    12721 ggctcgacgg cgaacccccg cgcgccggcc gcctcagcga tccgctgccc ctggccgccg
    12781 acctcggcgc cttcgtggcc gcgctgcgcc gggtccggct gcccgacggg ccgaccgcct
    12841 accggggtgt acccctgtcc accgccgatg ccatgacccg cgccgcgctc gacgagctgc
    12901 gcggcacgat cgacacctcc gccgccaccg ccgcctggga ggcggcgctc gccgcgccgg
    12961 cgtggaccgg tccgcccacc tgggcccact ccgacctgat gcccggcaac ctgctcaccc
    13021 gcggggaccg gctcgacgcc gtgctggact tcggcaccgt cggcgtcggc gacccggcct
    13081 gcgacctcat cccggcctgg aacctgttcc ccgccgaggc gcgggacacc ttccggcggg
    13141 cggcgggcgc cgacgacgcc gcctgggcgc gggggcgcgg ctgggccctg tccatggcgc
    13201 tcatccagct cccgtactac cgcgtcacca atccggtgat cgccgccaac gccgagcacg
    13261 tcatccacgc ggtcctcacg gaggccgacg ccagaccctg agacatcaat ggaacgtata
    13321 ttcgaatacg gagtacgctg gaggcatgtc cacgcacctc cagggctcgc tgttcgacca
    13381 gaccgacgag ctccacctca gtcagttgaa cgcgacgcgc cggacggtcc tgggcgacgg
    13441 ggcctggatc gacctgttgc ccggatggct cagcggcgcc gacgccctgt tcgcacggct
    13501 cgtcgacgag gtgccgtggc gggcggagcg gcggcagatg tacgagcacg tcgtggacgt
    13561 accgaggctg ctcgcgtact accgggcggg cgacgcgctg ccgcacccga tcctcgacga
    13621 ggcgcggcag gcgctgtccg cgcactacgc ccgcgagctg ggcgaaccgt tcaccaccgc
    13681 gggcctgtgc tactaccggg acggccgcga cagcgtggcc tggcacgggg accggatcgg
    13741 gcggggcgca cgggaggaca ccatggtcgc gatcctctcc gtgggcgctc cgcgcgacct
    13801 gttgctgcgc ccgcgccgcg gcggggagac cgtacggcgc ccactcggac acggcgacct
    13861 gatcgtgatg ggcggctctt gccagcgcac ctgggagcac gccattccca agacggcgcg
    13921 ggcggcgggg ccgcggatca gcgtccagtt ccgcccggac ggcgtgaact gagcgagggg
    13981 cgggcgttcc tgtccggcgg cgtccatcgc ctcacggcgt caggagtgcc tggaccgtgg
    14041 ggccgtaccg gtcgacgatg tcctcgatcg cggtcgcgcg cagccgggtg ccgcgcgcga
    14101 tgccgtacat cgcgccgagc ccgagcagtg tgccgacggc gagttcggcg cgcaggtccg
    14161 cgtcggggcc gctcagccgc agggcgaggc ggtcgctgac ctgggtgcgg aagttggcgc
    14221 gcatgacgtc gccctggtcg ccctggcgcg gggcgaagat gatccgcagg acggggtcgg
    14281 ctccgcgctc ggtctggccg acgagcacct ggcggaccat gtgggggccc agttggtcca
    14341 ggggcgcgtc caggagggcg gcggcatccg tctcgaagga catcacgcgc ccgaagagcg
    14401 cgtccttgtt cccgaagtac ttgaggatca gcggagcgct cacccccgcg cggtcggcga
    14461 tcgccttgag cgtgatgtcc gcgtgggcgt gccgggccat cagatgccgg gccgcgcgga
    14521 ggatcgccgc cttcgtggcc tcggcgtcgc ggcgcggtgg ggcgatcggg ctcgcgctga
    14581 ggccgggggg cggagtggac acggtgctca ggctccttcg aatgcctcgt cccgaggtgc
    14641 gtccgaactg ccggaggccc gtcgggtgtc acggagggtg gggtcggcgg gtatgacgag
    14701 ggcggcgaca caggccacca gtgcgaccgt acccgccatg gcgaaggcca gcagatagcc
    14761 gtgcagcgtg gggatcgggg cgccgccgac gaggctggtg tggtggacca ggatggcggc
    14821 gacggcggca ctgctcacgg cctggccgac ggtgcgcatc agcacgttga cgccgttcgc
    14881 ggacgcggtc tgccccgcgg gcaccgcgcg cagaatgagg gtgggcagcg ccgagtagga
    14941 gaacgccgtt cccatcgcgc agaccgcgga acccagcagg atcaccagca ggctgtggct
    15001 gttgatgatg cgtatgccgt agccggcggc gatgaccagg gtgcccagcg ccagcgtcac
    15061 ccgggcgccg cgggccgccg agatacgcgc cgagaccggc gagagcagca gcatgatcac
    15121 cccgccgggc agcaggacca gacccgtcgc cacgatggac agctcgaggc cgtagccggt
    15181 cgccttgggc gcctgcacca gctgcgccgt caccagggag ttggcgtaga aggcgaagcc
    15241 ggtcagaagc gccgcgacat ggggcagggc gacgcggggg ctggtcgcca gtttcaggtc
    15301 gaccagaggg cgcgcggcgc gcagttgctg cgcccaccac aggccgagga cgcagacgct
    15361 cccgacgaac aggccgatga tccgggggct gctccagccc cactggccgc cctgcgacac
    15421 ccccagcagc agacaggaga gccccagggc caggcccagc gcgccggtca tgtcgaagcg
    15481 gcccggctcg cggacgggcg actcgcgcac cgcccaccag gccagcgccg tcccgagggc
    15541 gccgaccgcg gtcgtccccc agaacatgac gtgccagctg gcgtactgaa ccacgatcgc
    15601 ggcgatcggg aggccgaggg cggcgccgat cccgacggtg gagctcatca gcgccaccgc
    15661 ggaacccgtg cgctcgggcg gcagttcgtc ccgcaggagg ctgatcgaca acggtacgac
    15721 ggcggccgcg gccccttgca gggcgcgggc cgcgatgagt atgcggatgt cggacgtgag
    15781 ggcgcacatg agcgagccga ccgtcatcat cccgagggcg atcagcagca ccttcttctt
    15841 gccgtacatg tcgccggcgc ggccgagtac ggggttgagc accgctccgg tcagcagcgt
    15901 cgccgtcacc atccaggaca cggcgcccgc cgacgcgccc gtcagccgcg gcaggtcggg
    15961 cagcagcggc accaccacca cctgcatgac ggccatgagg ctcccgccga gcgcgaggac
    16021 cgggaccgtc agtcggtcac gcagtgccac catgaactct ccagaagtcg gcgcgaagaa
    16081 ggggggtgaa tagcaattca ccatagccgg tgaattgcta ttcacccaat gggcgcccta
    16141 ctttcgggcg gcgctctgca ccgacagcag cgccgttcgc gtggctgcag gtgcgcgctc
    16201 ccgcacagca agtggtcacg gacggcgcgt gcggacccgg ggtcggcctc aattgaccac
    16261 gtagagcggc agaccggcgc gacccccgtg gttcgcgcca gcttgggggc gtgagccgcg
    16321 ccacccgcca ccgaccgccc cgggaagatc atcggcggaa cgtcggccga ccggaggaat
    16381 tccaccttcc ggtcgatcgc ggacacccgc acagcaagat catcttcgtt caaccttgca
    16441 cgacatttac ttaattgtcc tgatcacggc caaccgacat ccggcgattt cttccgctct
    16501 ccgacgaacc gataggcata tcgggtcatc gaccgagctt gatcgcagga ggtctccgca
    16561 tgccggaact cacccgtcgc cgtgccctcg gggccgcggc cgccctcgcc gccgcggccg
    16621 gcacccagac cgtcgccgtg gccagggccg cggacaccgg acaccacgtc gggcccgagg
    16681 ccttcgacga ggtgtaccgg ggtcgtcgca tcacgggccg cgccgccggc ggtggccacc
    16741 atcacgaaca cggcgccggg tacgccgtgt tcgtcgacgg ggtcgagctg cacgtgatgc
    16801 agaacgccga cggcagctgg atcagcgtcg tcagccacta cgacccggtg cccaccccgc
    16861 gcgccgccgc ccgcgccgcg gtcgtggaac tccagggggc accgctcgtc cccctcggca
    16921 tgcccatgcc catgcccatg cccatgccca tgcccatgcc tcagcagtga cccagccccg
    16981 tcagcacacc gtggagtccc gcacatgacc gtacgcaaga accaggcgaa cctgaccgcc
    17041 gacgagaagc ggcgtttcac cgacgccctc ctccagctga agcgcagtgg ccggtacgac
    17101 gccttcgtca ccacgcacaa cgcgttcatc ctcggcgaca cggacaacgg cgaacggacg
    17161 ggccaccgtt cgccctcctt cctgccctgg caccgcagat tcctgctgga gttcgagcgg
    17221 gcactgcagt ccgtggacgc ctccgtcgcc ctcccgtact gggactggag caccgaccgt
    17281 tcgccccgtt ccaccctgtg ggcccccgac ttcctcggcg gcaccggacg cagcctggac
    17341 gggcgggtaa tggacggccc cttcgcggcc tccgcgggca actggccgat cagcgtgcgc
    17401 gtcgacggcc gtacgtatct gcggcgctcg ctcggcagcg gtacccgtga gctgccgacc
    17461 cgcgccgagg tggactccgt gctcggcatg gcgacgtacg acatggcgcc ctggaacagt
    17521 tcctcggacg gtttccgcaa tcacctcgaa gggtggcgag gcgtcaatct ccacaaccgg
    17581 gtgcacgtct gggtcggcgg ccagatggcc accggtgtct cccccaacga ccccgtcttc
    17641 tggctgcacc acgcctacat agacaagctc tgggccgact ggcagcgccg ccaccccgcc
    17701 tccggctatc tgccgctctc cggcaccccc gacgtcgtgg acctcgacga gaccatgaag
    17761 ccgtggaacg acgtgaaacc ggcggagctg ctggatcaca ccgcgttcta caccttcgac
    17821 accgtctgac cgcgcgttcg caggcccggt cccgctcgcc cctcaggcgt tgctgggctc
    17881 ggccgtacgg cactcggggt gcccccagcc ctggccgttc ttggcgatgg gctcgcccgc
    17941 cgcgtacgag cggccgcaga ggcagcggcc cgggaacttg gccttgatcg tacgggccga
    18001 cgtgccctgc cggggcgtct tggcggaggc ggtggccgtg gtgcggcggc ggccggcgcc
    18061 ggagggggct ggggtgtcgg gggacggcgg gggctcaggg gagccgaggt cgctgccggc
    18121 gggctgctgg gcgatggcgg cctggctcgc ggcgcggtcg gcgaagtcgt tcagccggtc
    18181 gccgtcgacc tggtgggcgg ggacgtaacg gaactccacg gtgcggccgt cgaggagttc
    18241 gtcgatgcgc gcgaccagtt cctggttggc gaccggcttt ccggaggccg tcttccagcc
    18301 cttgcgcttc cagccgggca gccaggtcgt gacggccttc atcgcgtact gggagtccat
    18361 ccggatctcc agcgggacgt ccggcgcgat cgccgtcaac aggcgctcca gcgcggtgag
    18421 ttcggcgacg ttgttcgtcg ccgtgcccag cgctcccgcc tcccagcggg tcggcgtctc
    18481 cgcgccgtcg gccacgaccc acgcccatcc ggccggtccc gggttcccct tcgaagcccc
    18541 gtcacaggcg gccaccacac gttcaagcat gtccccgatc atgccacggc ccggcggcgg
    18601 ctccccgcac gggccgcagc gcgctctccc gcatccgggg gctggtgccg agcagccgca
    18661 gacccagcag cgtcgccgtg tgcaggacgt acttgccgtc acggaggctg gcgaccagtc
    18721 ccccgtcgcg cagcaccccg atctggtagc tggcgctggg cagcgcgatc cccacggcct
    18781 cggccacctc ggaggtggtg cgggcactct gtccggcgac ctcggtcagt acggcggccc
    18841 tggtgcggcc gagcagtcgc tcgaccccgc cgtccgtccc gtccgcgacg gcgagcggag
    18901 tcttcgccac cgggtacacg agcacgggat ccagaccggg gtccgccagc gcggtcggtc
    18961 tgcgccagca gaagtaggag ggcaccagga gaagtccgcg gccctccaga tacaggtcgc
    19021 gctggacggg atagtccact tcgagcaccg gggcactcca gcgcgcgacc gggcgcaggc
    19081 tctccagcag tgcctgggtg ccgccgtcga ggagggctcg ggcccgcacc ccgacatcgt
    19141 ttcccaccgc cgtgcggatg tgcggccagt gcggttccag gagaccgcgg aagtagatcc
    19201 ccagggagtt cgccagcacc ttgagcgcgt cgctgcccgg tctgcccagc gaggcggccc
    19261 agttcgggac cgggcgcgac tcggccagcc gcgacagttc gcgcaccagt tgcccacgcg
    19321 gtgtgcgcag cagttggtcg agtccggcgg aaagaccgcc gccggtgacc ggcggggtga
    19381 ggaagtccgg gatatagccg gtggcgggga tcagggcgcg cagtgggcgc agcgcgcgga
    19441 ccaggttcga gtcgccggag aatcgttgcc gagccgagcg acgccaatgt ccgaattcca
    19501 gcggtccctg gccggtttcc agacggcaga cactgcacat cagttcccac aggggatcag
    19561 gctgccgggc cactcgaatg ttctgaaggt cgtccgaagt gaagtgaatg cggagcatga
    19621 ggtctctttc gctcgcaatc cttgtggggg gttcggccgt tcgaacgtgc cgcaaccaca
    19681 agaggggacg agtaccgcat gcgcatggtt gcccgggagg caaagggccc ggtccgcccc
    19741 ggaggaattc cgccattccc cggggggccg gtccgcgggc gatccgtggt ccgttcagga
    19801 cacgtcggtc gccttgggca tcgcgccctc ggtggtcttg acgtcgatca cggagaacgc
    19861 cgcgccctgt gggtcgctca gcgcggcgaa gcggccgaag gggctgctca tcggcccgaa
    19921 gcggagaatc gcgccccgtt cggtggcctt cgcgaccgcg gcgtcgcagt cctcgacggt
    19981 gaagtacacg ttgaagtacg gcgggacctc gggcgggaag tcgtccgtca tccgcatccg
    20041 gccgaggacc gggtccttgc cgaggtcgta cagcctgaag tcgacggcgt cgtcgtccag
    20101 ctgcttcatg cggtacccga agacggccga gaagaaggtg tccgacttct cgggctcacg
    20161 ggtgaagacc tcggcccagc agtacgcgcc gggcacgccc cgggcctcga agccctcgtg
    20221 gcggccgggc tgccagacgc cgaagacgac cccgctcggg tcccgggcga tcaccatcgt
    20281 gccgaaatcg ccgacctgca tcggctccat cagcacctcg ccgccgtcgg cccggatctt
    20341 ctgggcggtg gcggcggcgt cgggcgacgc gaggtacaga caccaggcgg actggccctc
    20401 ctggccgggc atcggcggga cgacggcggc caccgccttg ccgttcgcgt aggcctgggt
    20461 gtagttgccg tactccgagg acgactcgcc gaacgtccag ccgagcacgt caccgtagaa
    20521 actcttcgct ccctcgacat cgctgaacat cgcgtccgcc cagcagggcg ttccctcggg
    20581 ctgtacggcc atggcgttcc actcttcccg gttcgttacg gttcgttacg gtccattccc
    20641 gtttcacgct agccagcctc cgtccgggcc gcgcgccgag cggggcgccc tggacgacac
    20701 tggagagagg gctcgggtgg tcgtcgacgg acggggacac gggatgatgc acgcgtggga
    20761 agtggccagg cccgggccgg tcgaagggga accgctgcgt ttcgtcgagc ggccgatccc
    20821 ggtgccggcg gccgacgagc ttctcgtcca tgtgcgcgcg tgcggagtgt gccgcaccga
    20881 cctgcacgtc accgagggag acctgccggt gcgccgggcc caggtgacgc ccggccacga
    20941 ggtcgtcggc gtggtcgcgg cgacgggcgg ggacgtcctc gaccacgcgg tcggcgaccg
    21001 ggtgggcgtc gcctggctgc accgtacgga cggcacgtgc gggtactgcg cgcgcgggtc
    21061 cgagaacctc tgccctgcct ccgagtacac gggctgggac gccgacggcg gctacgcgga
    21121 gtacacgacc gtcccggcgg ccttcgccta ccggctgccc ggcgaggtgg acgacgtcgc
    21181 gctggcgccg ctgctgtgcg cgggcatcat cggctaccgc gcgctgctgc gggccgcgct
    21241 gccggacgcc ggacggctcg gtctgtacgg gttcggcggc agcgcccatc tgtgcgcgca
    21301 gctggccctc gcacagggcg ccaccgtgca cgtactgacg cgtgacccgg ccgcgcggcg
    21361 gctcgcgctg gaactcgggg ccgcgtccgc ccggggcgcg tacgacgagc cgcccgagcc
    21421 gctggacagc gcgatcctgt tcgctccggt cggcgacctg gtcccggtcg cgttgcgggc
    21481 cctcgaccgg ggcgggatcc tgtcggtcgc cgggatccat ctgagcgaca ccccgccgct
    21541 gcgctacgag agcgacctgt tctacgagaa ggagctgcgc agcgtcacct ccaacacccg
    21601 acgggacggg cgggacttcc tggcgctggc ggcccgccac ggtgtacgcg ccacgacgca
    21661 cgcctacccg ctgtccgagg cccagcgggc ccttcgggac ctcaaggccg gccgtttcga
    21721 cggggcggcc gtgctcgtga acgacttccc ggcgcgcacc tgagcatgcg cgcccgcgac
    21781 gcgcgtgcgt ggatggaacc agacgtgtgt gcgacggtgg aggtggcatg acgatccgag
    21841 gcggtgacga cgctacgggg gcaggggcgt cgttcgccat gagtgaggac gccgtcgagg
    21901 cgatcggcac caccctggac gagcggatca cctgcgagga gctcgcggag ttcgtgtgcc
    21961 gggaggtctg
//
