LOCUS       NZ_CP041604            23532 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. S1A1-7 chromosome.
ACCESSION   NZ_CP041604
VERSION     NZ_CP041604.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. S1A1-7
  ORGANISM  Streptomyces sp. S1A1-7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 11713216)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 58.0x
            Sequencing Technology :: Illumina MiSeq; Oxford Nanopore GridION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007113565.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:07:15
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,902
            CDSs (total)                      :: 10,801
            Genes (coding)                    :: 10,337
            CDSs (with protein)               :: 10,337
            Genes (RNA)                       :: 101
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 80
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 464
            CDSs (without protein)            :: 464
            Pseudo Genes (ambiguous residues) :: 0 of 464
            Pseudo Genes (frameshifted)       :: 185 of 464
            Pseudo Genes (incomplete)         :: 374 of 464
            Pseudo Genes (internal stop)      :: 46 of 464
            Pseudo Genes (multiple problems)  :: 127 of 464
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:07:12
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1782415
            Orig. end                         :: 1805947
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041604.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041604.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23532
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="guanidinotides"
                     /region_number="7"
                     /rules="(pgm1 and pgm_amidino)"
                     /tool="antismash"
     cand_cluster    1..23532
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(pgm1 and pgm_amidino)"
                     /kind="single"
                     /product="guanidinotides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23532
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13532](-)"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13532)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
     gene            complement(337..1146)
                     /locus_tag="FNV64_RS09660"
                     /old_locus_tag="FNV64_09830"
     CDS             complement(337..1146)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09830"
                     /product="hypothetical protein"
                     /protein_id="WP_143654437.1"
                     /transl_table=11
                     /translation="MLVGAGLLTAAQFISDTTDFLRSGTDGSATYYSPGPGYWWGITSC
                     ALCLASAVLALIALRRCGALRIRATRVGIFWAITGMVLAIGWLIGTWMPWQKTTLTSTV
                     AEATKTVTLSECCSLSDMPGQFLAEAALAFVLLIAVALIGACISSAATASGAILGSAFC
                     AGASIVPGLMNKAPSIADVASAWGDTVTEDQLRQAQAATALHHLPGLWLTAASVVGLIL
                     LATARGMHGMVSAAGPDSVVYAERESAGSPTAAQVLLSPENSPKTGP"
     misc_feature    complement(1212..1226)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            1842..2528
                     /locus_tag="FNV64_RS09665"
                     /old_locus_tag="FNV64_09835"
     CDS             1842..2528
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09835"
                     /product="hypothetical protein"
                     /protein_id="WP_143600240.1"
                     /transl_table=11
                     /translation="MESGLNDFWRDVMKLQEPPYREPVDDEVLHLQDQVAEAARDLARA
                     ISTRESAYRADGQEAPDGIALSPDWQLAYLYALHEIEGIARRLADGAARTAGGTGASYP
                     QLGAAWGITKQAARLRWPGAVRKPDDTSGEGEPFELWLSGGLAEIIQLPNEGGFIWKAT
                     GGNGTSGQAEEPYGNRTEAAAHAGAFLARHAAADDDPYGPDAAHAGCVEPHLGPDGYVD
                     CDGTPL"
     misc_feature    2615..2628
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.92"
                     /tool="antismash"
     gene            2628..3611
                     /locus_tag="FNV64_RS09670"
                     /old_locus_tag="FNV64_09840"
     CDS             2628..3611
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075545.1"
                     /locus_tag="FNV64_RS09670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09840"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_143654438.1"
                     /sec_met_domain="APH (E-value: 3.2e-19, bitscore: 69.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFRPVPRDPEAFQQSVTAEDIHAIALRAFGRSVRITSAVELGGG
                     MYNNTYRLLAEGLDGPVILRIAPAPQRQFASEHELMRNEYATVPFLAPIADLVPRVLAA
                     DWSQEITGRDWMVQSHLDGTPAPDRLGDYPRTLWQGFFAQLGTITRNIHAVAGPRFGPV
                     AGPGYATWSEAVLASLTAIADDVSRVGLDAADVRKAADLAAEHHKVLDEITEPRLLTGD
                     LWTVNTMLAAAPTPVISGVLDLDRTLWGDPAADWTIRMASAKTDERTAFWDTYGPCAAT
                     SAHAWRALVYEARHLGAIRLERHRLHNPSGVDDTYSSMAAVLAQLI"
     gene            complement(3957..4250)
                     /locus_tag="FNV64_RS09675"
                     /old_locus_tag="FNV64_09845"
     CDS             complement(3957..4250)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09845"
                     /product="hypothetical protein"
                     /protein_id="WP_143600248.1"
                     /transl_table=11
                     /translation="MTWLFTATIRSVRQLVTVFCRSCLLLLCRSTDGGTDGGNSMDITA
                     WVVLVPVVAMLIAAIAAVVIVVVAVQDTTACARAEVLKAVAEVIRAVRGSRR"
     gene            4313..6109
                     /locus_tag="FNV64_RS09680"
                     /old_locus_tag="FNV64_09850"
     CDS             4313..6109
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017539.4"
                     /locus_tag="FNV64_RS09680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09850"
                     /product="NACHT domain-containing protein"
                     /protein_id="WP_143654439.1"
                     /transl_table=11
                     /translation="MSEPIQLPVGRRVLRDELRMLERKALQREGKNRTDAIEKANAQLE
                     PLGLPKLKTSTVSDWIEKGNPAKNFLVLWALVRVFLEWSGGLPPKGATTPKDPVGAKAK
                     AAWNYTEEGWRLRWEDAKRSRPPTPAPENARLLTAYLRAARDAAGQHPYRSTRQDLKLP
                     ALADVYVRQHTRTRAQGNEASAAVPAAQVFRADHSICLLLGAPGGGKSTLLRTHLAQTA
                     EALLSNTAEKTIPILLRAAALTTTDPLPAALARTVTADLQQDGLLDELPTGFFRRPPRT
                     GASWLVLVDGLDEIPDTDTRSAVMTKLANVSANSEGLYRFVVATRPLPAQELLKLGDRV
                     AHYELQPFSHDDLYTYATHWFRSLDNPRRHTEAFIAGLTHSGLEVLARTPLMALMLCQL
                     YLTDPTRPLPAGRAGAYQEFVKWIYEQNTHKNIKNTHDQAIRRLKDRHQIPEESDAAES
                     AAEQVRQHLRGLIDHLAYERLNGRRGAAVDILASHLQVNRPREVEQHLWNAFLGDLMRP
                     TGILTQHGDDFDFLHQTLLEYRAARHATRNEQTCTQLLNDLIASSTVRSDGRLGPVWSC
                     DQGCDPRCRIQRRPAHNSSPAW"
     gene            complement(6043..7016)
                     /locus_tag="FNV64_RS09685"
                     /old_locus_tag="FNV64_09855"
                     /pseudo=""
     CDS             complement(6043..7016)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612357.1"
                     /locus_tag="FNV64_RS09685"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09855"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSRPQLSDAEWEFVSPFLPVGEYGPYPENLRAHFEGVVWRFRNGA
                     KWRELPERFGHWSTVYGRFRQWRDAGVFTAVFQGAIAEAAKRGLVDLSLVSVDSTTVRA
                     HHDAAGMIVEPETLDALEKAAAEKGAPARNKTGNWTRSGKNDDA"
     gene            7197..7880
                     /locus_tag="FNV64_RS09690"
                     /old_locus_tag="FNV64_09860"
     CDS             7197..7880
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09860"
                     /product="hypothetical protein"
                     /protein_id="WP_143654440.1"
                     /transl_table=11
                     /translation="MQHGGEGTHRFLTTQVYLKTNLPPGPTAVCLARLADNPALDGLAR
                     VTAARALAEVDSNAGAHHLARLADDPTLNDGSHLEAARALAEVDSKAGAHHLARLANDP
                     TLNDDFRVRAARALAEVDSKAGAHHLARLANDPTLNDSFRVEAARALAEVDSKAGAHHL
                     ARLANDPTLNDSFRVEAARALAEVDSKAGAHHLARLANDPTLDDFSSGRAARVLAQTEA
                     RGRGR"
     gene            complement(7954..8760)
                     /locus_tag="FNV64_RS09695"
                     /old_locus_tag="FNV64_09865"
     CDS             complement(7954..8760)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (60-185). E-value: 1.1e-08. Score:
                     25.5. Matches aSDomain: nrpspksdomains_FNV64_RS09695_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="FNV64_RS09695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09865"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_143600250.1"
                     /transl_table=11
                     /translation="MSTPPAGRAADTAGHQTTSALEFDRLFGTEGTEGHGSAFSTIARL
                     VDPDLPPDLDLFSFLCADLLHHLARQLDLRPRQILADLGCGRGGPGLWLAGRAHATLVG
                     IDFSPVAIAQARHRAVPFAADAAFAVADLALLPLTSQCVDEALSLDALQYAPDRVAAAR
                     QVLRILKPGGRLVLTGWHPHTPGDERLPPRHRHTDWTRVLHTAGFTDVHCTSTPAWDDA
                     YQGIYRTALTLHAEPGSALAGLQGEARRRLPTAHLLRRVAVTAVRD"
     aSDomain        complement(8206..8580)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV64_RS09695_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-08"
                     /label="FNV64_RS09695_oMT.1"
                     /locus_tag="FNV64_RS09695"
                     /protein_end="185"
                     /protein_start="60"
                     /score="25.5"
                     /tool="antismash"
                     /translation="CADLLHHLARQLDLRPRQILADLGCGRGGPGLWLAGRAHATLVGI
                     DFSPVAIAQARHRAVPFAADAAFAVADLALLPLTSQCVDEALSLDALQYAPDRVAAARQ
                     VLRILKPGGRLVLTGWHPHTP"
     gene            complement(8757..10004)
                     /locus_tag="FNV64_RS09700"
                     /old_locus_tag="FNV64_09870"
     CDS             complement(8757..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014805.4"
                     /locus_tag="FNV64_RS09700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09870"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_143607128.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.2e-12, bitscore:
                     47.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 3.9e-10,
                     bitscore: 38.8, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPVMLLEAAGPESEALARTAAAAGHPVHAVTDAATLASYSGEL
                     RQLLEGCLVTGFTRPGQAVADITGYGRRIGVKALLTVNEYLTEVAARSCAALGLPGNDP
                     ERAAAARNKALMATAFEAGHVTMPRTKAVADLRELRGLHEAGAVGFPCVVKPADGAGSA
                     GVTVVTGPEELEPAWHAARTARVMYGMLRDERILVQEHVQGREFSVEYITQHDVTTHLC
                     ITRKHTTSGIHRVELGHTLPARLPAAAERALLEQAGRAIAAVGVRNGATHTELVLSPDG
                     RCTVLEIGARLGAGHIGVLMQHALGIDPWRTVWDIALGRPVTITQAPGGYATVRFLTTH
                     HAGRLVAVTGLPAVTTTIPAVRVRAAEGSDVGPATSNRGRLGHVIVTGHDPRTVDERAD
                     QILRQITITVAPGSRT"
     gene            complement(10001..11146)
                     /locus_tag="FNV64_RS09705"
                     /old_locus_tag="FNV64_09875"
     CDS             complement(10001..11146)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm_amidino"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827973.1"
                     /locus_tag="FNV64_RS09705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09875"
                     /product="glycine amidinotransferase"
                     /protein_id="WP_143607129.1"
                     /sec_met_domain="pgm_amidino (E-value: 1.2e-169, bitscore:
                     563.1, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLNSYDDFTPLSEIIVGSAENYVGHDRDLTFELFFHVAIGGYR
                     SDWAYPRLAAGGSEQAETWKIGKRYTEELHEDVENLAATLTSLGITVHRPLPLPTDALP
                     IAGLGWQAAPTPALNVRDNTLVLGDEIIETPPAVRSRYLETRLLSQVFRSYFDTGARWT
                     TMPRPVLTDRSFDLSYAQSAATTLGGPTEPITDPQPSPYDVGVEMMLDGAQVLRLGQDL
                     IVNVAQDNHRLAVDWLKRHVEGRFRVHTVYRMADNHIDSMLLVLKPGVFLARHAGLREI
                     LPDAFRTWTFIVPPEPEPGQFPVYTDSELLLTSPYIDINVLSLDEQRVLVNADCLGLIK
                     TLENEGFTVIPVQHRHRRLFGGGFHCFTLDTHRAGGLVDYR"
     misc_feature    complement(10838..10840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11167..12144)
                     /locus_tag="FNV64_RS09710"
                     /old_locus_tag="FNV64_09880"
     CDS             complement(11167..12144)
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016974.4"
                     /locus_tag="FNV64_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09880"
                     /product="aspartyl/asparaginyl beta-hydroxylase
                     domain-containing protein"
                     /protein_id="WP_143654441.1"
                     /transl_table=11
                     /translation="MTTTTPARPAPAAPLTPAFDADRLAHELSAVTGHPWQRQRTHYAA
                     GRIGPDTPTDWRVLPLRSPGGDPTRTDPGGPGPDQYAATRWLDQMPYLREILDEIPAPL
                     NAVRLLALGPGAASQPHRDPKYALQRGMVRLHIPIATHPGAVLVLDGTEHRWQPGTFWY
                     GDFSREHMVANTGSVRRVHAVIDALFTRELATLFPTEWQESLGYADVLFNRLPDPALRP
                     SPPLPRAVNLPAGFTDFSQDTPLEGPTVPVRLTERDGDLVLTHAERGFALVHVVDGEYR
                     YAGWSEQRTLQLGNDHVVLHARHGRALTSQHVSLPAADSSPAGA"
     gene            complement(12141..13532)
                     /locus_tag="FNV64_RS09715"
                     /old_locus_tag="FNV64_09885"
     CDS             complement(12141..13532)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF037360.4"
                     /locus_tag="FNV64_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09885"
                     /product="hypothetical protein"
                     /protein_id="WP_143607131.1"
                     /sec_met_domain="pgm1 (E-value: 5.6e-136, bitscore: 452.7,
                     seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIIIANHIDPAIRDRHDLRAWTQRALWGARNGDLVVLCAPPDPH
                     FLRYATALTGTDPNRLHLVVAPTGAYGGRLLDPQMLTHPDTLDQVRAYLAKHGGPDAVG
                     EIWALWPSASVARFATALGLTEKLPGCDFLAQGGGELVNNKAVFRTLAAAAGVPVAAGT
                     VVRDPGEAAAATLTLLQRSGAVVVKQAHNGAGVGNELLVTDPTLATGHAGARHLHHLGR
                     TDLPAAAAAYWRERWTWASADGRFPVVLEEFIPGAFTVYCEQHLTETGTQPTERGELRY
                     TDRRLSHESVPLRDLSAAVEEQLLDGSARLAHTYRSVGYRGRISTDAIVGPDGRLLFTE
                     VNAQVSGSWHIYEVFAHHIVHANETPERTVTESHIPPEWTLPDGSTFHRALAELGLGYD
                     PATRSGVIVSMPIVDHPSLGAQFTFSTVHASPADRDAIWHALEDRFTTTSSTARRTDSR
                     KALAR"
     misc_feature    complement(13518..13533)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(13567..14748)
                     /locus_tag="FNV64_RS09720"
                     /old_locus_tag="FNV64_09890"
     CDS             complement(13567..14748)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="FNV64_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09890"
                     /product="cytochrome P450"
                     /protein_id="WP_164657610.1"
                     /sec_met_domain="p450 (E-value: 2.1e-10, bitscore: 39.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTPTCPVRYDPLDEATLADPYPVLAALRAQAPLVWHDTMESWL
                     VTGYDDCVRVLRDHEAFARDPRRLGRTVPEASLSVQVLDPPHQAAVRSAFMTSLHAQDL
                     PVLQERTRRDIAARLEVLASQPAWDVMRELAQPVALDAIADLLGVTPPPLSAWVQVSDT
                     IMRSMDGGLNPDLVEPGRLAREKLSELVASWFTTTGSPAGLLGHVRTRTADAGPELARY
                     VVHTARVMFQGGYSTLAAAIGNAVDTLARNPQAQRALRETPQLRATGVDELVRYDGPVQ
                     GTSRLAATDVLLGGRTVHRGEKVTVLFQAANRDPAHFEHPDRLVLDRSPNRHLGYGWGT
                     HACLGTTLAQRVLVALLDALADHPGLLHPAGPARRRHTATMRAFDHLPVTLQP"
     gene            15031..16347
                     /locus_tag="FNV64_RS09725"
                     /old_locus_tag="FNV64_09895"
     CDS             15031..16347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383632.1"
                     /locus_tag="FNV64_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09895"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_143607133.1"
                     /transl_table=11
                     /translation="MEETTGHPLVVARHAAGKTMEEFVSGIHASAARRNLRSGIDEARV
                     RKWQRGVQPSEESQIYIAEALGWPADIVRADDWPNWLPLTANGVVPLGPHSSVPALREA
                     QRTAMERRTFLTISGAALSALAADWAGGPADALAQAHDGKPIGEDLVAFLENSTRHLAG
                     LSTEQRQHTPALLDAHLATVTELLENGRYTPALGLRLHTLAASLSQTVAWHAFDLGRHT
                     HASQSWVAGLHNAHAAGDHDMGAGLLGDLAYQAAWRRDHITAASILGHALTRAQNPAAR
                     CLLQLRLARTLAARGDRSERRAVLRALAAAEKHLNDAGTERPAWCAWVGAADLAVDSGQ
                     ALLDLGDTARAHQLITEGERLLPTARDKTRGVFLAYRAASYLDLKEPEAAAAAATQSLL
                     LARRIGAPRCVQLVDDLLPRFQPYARAQGVPELLQLTAA"
     misc_feature    15490..15492
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16690..16869
                     /locus_tag="FNV64_RS09730"
                     /old_locus_tag="FNV64_09900"
     CDS             16690..16869
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09900"
                     /product="hypothetical protein"
                     /protein_id="WP_143600258.1"
                     /transl_table=11
                     /translation="MLSLLDGCTAKDATFVVMGDDSLWTARSAWTDAQRSLIQEYTGSD
                     RRAGKDRTYADGDS"
     gene            complement(17182..17784)
                     /locus_tag="FNV64_RS09735"
                     /old_locus_tag="FNV64_09905"
     CDS             complement(17182..17784)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09905"
                     /product="hypothetical protein"
                     /protein_id="WP_143600259.1"
                     /transl_table=11
                     /translation="MTVAHDAYVRQLIARAKDGTIPPQEVKQIAQAVTECRAGRELYQR
                     LYAVARAGGPAYEPLIAAYLIYPEDPEVSALAVQVLTAHWRVGAKYRKQILELLGSPEW
                     DLDDDVFMAAVSGAGWILHDGFDAELLRALLKLAEEGRGEYNDDLMQGLAVEATARALG
                     ASHAELTRLPEGVTRAEWSQGLLRAARDRLHEAARQP"
     gene            complement(17946..18296)
                     /locus_tag="FNV64_RS09740"
                     /old_locus_tag="FNV64_09910"
     CDS             complement(17946..18296)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV64_09910"
                     /product="hypothetical protein"
                     /protein_id="WP_143600260.1"
                     /transl_table=11
                     /translation="MNPLEDDLKQVRVELAAAELESQRLEAQIAALRAKEATLEGLIVK
                     APELNVQGMTKAEAIVAALAQSSEPMTLGQIADTVTAAGSVLKPDGASVYLDGLLKMGK
                     VVRVKRGLYRAA"
     gene            18727..19110
                     /locus_tag="FNV64_RS55025"
     CDS             18727..19110
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017416.4"
                     /locus_tag="FNV64_RS55025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_225900164.1"
                     /transl_table=11
                     /translation="MQVARASNPGGTTAIWVRDRLDGLWCDEDFADWYPRDGRPGLSPA
                     QLATVCVLQFLLGLSDRQAAEAVRCRIDFKYAMAMELDDPGFHHSVLADFRDRLAEGDR
                     ADRLLDLALARLKEAGLVRERTT"
     gene            19141..19959
                     /locus_tag="FNV64_RS55030"
     CDS             19141..19959
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV64_RS55030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225900165.1"
                     /transl_table=11
                     /translation="MRDLTRLELITEAVRAALEEVAGTSPHLLDELVDEDWGLRYGRPV
                     RLGKNPTRPKTRILATGNDAVRVLEHLYRHGTDHTFGPRIQALRQIMVQNYHHDGAGHL
                     RWRTAETEGDPGLPPSSLAVVSPYDTSARYARHGHIISWKGFSAHLTETCAPDGPNVIT
                     DVATTAATTHDSQVLPGIHTRLARRGLLPAEHLVDAGYTSLPHLEQATREHQVTVSGPL
                     RSDPTRQHRRNEGFARDDFHIDYDRQQVTCLQGQGVGTAPTRPPLPPRPR"
     gene            19962..20381
                     /locus_tag="FNV64_RS55035"
     CDS             19962..20381
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /locus_tag="FNV64_RS55035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_240361189.1"
                     /transl_table=11
                     /translation="MARFAKSQCRPCPARTQCTSTADSARTVGFPPREPRDLQLRVRAE
                     QQTPEWKTRYAVRSGVEGTVNEFAHGHGMRRCRYRGQGKAHIQHVLTAIAVNIERLSEL
                     PPTEETPTPRRPTALQNYLDQREIRRLKSWRTLGS"
     misc_feature    20699..20714
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            20819..21835
                     /locus_tag="FNV64_RS09750"
                     /old_locus_tag="FNV64_09920"
     CDS             20819..21835
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983601.1"
                     /locus_tag="FNV64_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09920"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_240363348.1"
                     /transl_table=11
                     /translation="MARSPQERGVPHSAGARDRLLPVLPALLLFGGLLFGLFTPRDVRP
                     DAFLATAMVSAAALLSLRGTVLTGVGACAIFVCLMVDFNGLRDATAYSELATLVAIAAF
                     AVFFNRLLGRRAHQLVQVRSVAETAQLAVLHPVPRHLGHVTLESLYLAAAAEARIGGDL
                     YEAIRTPHGVRLLIGDVRGKGLLAVRTAATLLSAFREAAHDAPDLPHLACRLETSMSRH
                     ASQYPGVPGSEIAERFITALLAEIPDDEPVVRTVTCGHPPPLLLHRGEVRELQPAAPSP
                     PLNLGMLMSDGYHVDLAPFHPGDQLLLYTDGVTEPGSTGLMSVDSFSGNEEVPCDLR"
     misc_feature    20850..20866
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     gene            21886..23274
                     /locus_tag="FNV64_RS09755"
                     /old_locus_tag="FNV64_09925"
     CDS             21886..23274
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_040423240.1"
                     /locus_tag="FNV64_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV64_09925"
                     /product="IS1380 family transposase"
                     /protein_id="WP_143653766.1"
                     /transl_table=11
                     /translation="MQSSHAAAAVSSAFDDPNLIAYGGLEPVVRLAERCGLPALVGEYI
                     RLPASKDGTGAFPAAKVMSLVGGMVAGADSIDDMHRLRHGAMGRLFSGVRAPSTLGSFL
                     RSFTHGHVKQLHAVARRFLPELARHAPLLPGADQVAYVDIDDTIRRTYGYAKQGTGYGY
                     SKVKGLNALLGIVSTPLATPVIAATRLRKGPSNSARGAAAFVAETIRTARACGANGLLV
                     MRADSAFYGADVVNSCRALGARFSITVRMNASVKAAIARIDEDAWMPIKYPKAVWDEEG
                     QCWISDAEIAETGYTAFTSKPKKQQVTARLIVRRVKRLSTGTVPAGQGTLFDTWRYHAA
                     FTDSPLSLNDAERDHRRHAVVEQVIADVKNSAFAHAPSGHFQANAAWLALAALAHNLTR
                     AAGALAGTFHARATTATIRDHLINVPARLARSARRLTLHLPERWPWSTDFTQLFSIVHA
                     PPAP"
     misc_feature    complement(21925..21943)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.69"
                     /tool="antismash"
ORIGIN
        1 ccggaaagca ctcccgcccg cagatcacgg ctgaagtcca tatacacacg ttacgacgga
       61 caaggcatgg acgctggatg ggaggcaagc cgtccgcgcg atgcgtgcct ccatgagacg
      121 gcgcgtccct acctgatcgg gtgatagcgc cacacctgtt gcgcgcggta gtgtccttca
      181 cactgctgct gagctgcacc gatccttatc ggatcacgct gcacgacggt tgacccccag
      241 cgtggcctgc agttcgctga cgttccacca gcgggtctca cggatgttgg cggtctgacc
      301 ggcatcgaaa tccagccgga ctggcgaggg ctgttctcaa gggcctgtct tgggagagtt
      361 ttccggggag agaaggacct gagcggcggt tggcgagccc gccgactcgc gttcggcata
      421 aacaaccgag tccggccctg cagcggagac catgccatgc atccctcggg ccgtggctag
      481 gagtatcagg cccaccacgg acgcagctgt caaccacagg ccagggagat gatgcagcgc
      541 tgtcgcggct tgcgcttggc gaagttggtc ctccgtgacg gtgtcccccc aagcgcttgc
      601 gacatcggct attgatggag ccttgttcat gagccccgga acgatgctgg ctcccgcgca
      661 gaaggcggag ccgaggatgg caccggacgc ggtggcagca ctcgatatac aggcaccgat
      721 caacgccact gcgatcaaga gaacgaaagc tagggctgct tccgcgagaa actgcccggg
      781 catgtcagag agcgaacagc actcggagag ggtgacggtc ttggtcgctt cggcgactgt
      841 gcttgtcagc gtggtctttt gccacggcat ccaggtgccg atcaaccatc cgatagccaa
      901 gaccatgcca gtaatcgccc agaagatgcc gacccgggtg gcgcgtattc gcagggcacc
      961 acagcgtcgc agagcgatga gagccaaaac cgcgctcgcc aggcacaggg cgcaagaggt
     1021 gattccccac cagtaacccg gacccggact gtagtacgtg gcggagccgt cggtgccgct
     1081 ccgcaagaag tcggtggtgt ccgagatgaa ctgagcagcc gtgagcaacc cggcgccgac
     1141 cagcatgcca gcaccgaacc tgctcgtgcg cgaaaggaag gcgaggagag ccgcgattac
     1201 gatggaacca atgaaaacgg cgttgaaggc gacagttgag gatgagtcct tgagtcgctg
     1261 agcagtagcg tcagccccct ggtacccgta gaccgggaac aatgcagcga gtgtgcaaac
     1321 agcggccgcg attcccagcg ctgcggcaga catacgccag gcaggtggag gagcctcgac
     1381 gtagacggcc gtgggccctt tcaggggttg tccgcaacgg gtgcagtaga ccccttgcgg
     1441 tatggctgga gtgccacagg acgtgcagaa catgtatccc tcgccagctg gttccagccc
     1501 ccgacgaggg cgcgagcgga catcgtactg gcagcggact ctcgaatcag gagaccgggt
     1561 cctcgacgac gttcgacgcc ttggtgatga actccatggg aagctcagcg tgcatggccc
     1621 ggttccggcg ggagggacgt cagggacggg tggcggcgat ggcttccgtc cggacgagct
     1681 cgtcgaacgt gctggccggg ctgatctctg tcagggcccg gcacacgtcg tgctcgaagg
     1741 cgtccgtgtc gctgaggccc cccccatgag tcagtggcga ggggcacaac tggcgacaag
     1801 tccacttgtc accaactgtt gcgacaagta ttcttgtcgc tatggaatcc ggtctgaacg
     1861 acttctggcg tgacgtcatg aaactgcagg agcccccgta ccgagagccc gtcgacgacg
     1921 aggtcctgca cctccaagac caggtggcgg aggccgcccg cgatctggcc cgtgcgatct
     1981 ccacgcggga gtccgcctac cgcgccgacg gccaggaagc ccccgacggg atcgctctct
     2041 cgccggactg gcaactcgcg tacctgtacg cccttcacga gatcgagggc atcgcccggc
     2101 ggcttgccga cggcgcggcg cgcaccgctg gcggcaccgg agccagctat ccccagctcg
     2161 gggcggcctg ggggatcacc aagcaggcag cgagactgcg ctggcccggc gccgtgcgca
     2221 aacccgacga caccagcggc gaaggtgaac cgttcgagct gtggctcagc gggggtctcg
     2281 ccgagatcat ccaactcccc aacgagggag ggttcatctg gaaggccaca ggaggcaacg
     2341 gcaccagcgg tcaggccgag gaaccgtacg gaaaccggac cgaggccgct gcgcacgccg
     2401 gcgccttcct tgcccgccac gctgccgcgg acgacgaccc gtacggtcct gacgcggcgc
     2461 acgctggctg cgtcgaaccc cacctcggcc ccgacggcta cgtcgactgc gacggcacac
     2521 ccctgtgaat ccgcgcggca cgaaagacgc gggagcactg ccgatctggc gcacagcaag
     2581 catgcgatga ccgatccggc cccggacaag gccgtataag gagtgtcatg gacttccgcc
     2641 ccgtcccccg cgaccccgaa gccttccagc agtccgtcac ggccgaggac atccacgcga
     2701 tcgctctgcg tgccttcggc cgcagtgtcc gcatcacctc ggcggtcgag ctgggaggag
     2761 gcatgtacaa caacacctac cggctcttgg cggaaggcct cgacgggccg gtcatcctgc
     2821 gtatcgcccc cgctccgcag cggcagttcg ccagcgagca cgagctgatg cgcaacgagt
     2881 acgccaccgt ccccttcctc gctcccatcg ccgacctcgt tccgcgggtc ctggccgccg
     2941 actggtcgca ggagatcacc ggccgggact ggatggtgca gagccacctc gacggcacgc
     3001 ccgcccccga ccgtctcggc gactaccccc gcactctctg gcagggcttc ttcgctcagc
     3061 tcggcacgat cacgaggaac atccacgccg tagccggccc gcgctttggg cccgtcgccg
     3121 gacccggcta cgccacgtgg agcgaggccg tgctggcctc cctgaccgcc atcgcggacg
     3181 atgtcagccg cgtcgggctg gacgccgcgg acgtgcgcaa ggccgctgac ctcgccgccg
     3241 aacaccacaa ggtcctggac gagatcaccg aaccccggct gctcaccggc gatctgtgga
     3301 ccgtcaacac gatgctcgcg gccgcaccca cgccagtcat cagcggtgtc ctcgacctgg
     3361 accgcaccct gtggggcgat ccggctgccg actggaccat ccgtatggcc agcgccaaga
     3421 cggatgagcg cacggcgttc tgggacacct acgggccctg cgccgccacg tccgcccatg
     3481 catggcgggc ccttgtctac gaggcacggc atctgggggc gatccggctg gagcggcacc
     3541 gcctccacaa cccctccggt gttgacgaca catactcctc catggccgcc gttctggccc
     3601 agctgatctg aacgttgctg cctactgccg agttctagga tccgcggctc cgctagcaat
     3661 gaaggcagtc cgtgagcagc agattcgcaa atccgcgatc ccggtgacaa tgactacgtt
     3721 caggggcgat ctccgccggg tctctttcga tcttctctgc gcgtgtgctg cccgtgctcc
     3781 gtatcgtcct tcctggctgg caactgctcg cctttctcgg gcggctgtaa cgagcgtgtc
     3841 atcagccgcc aaacaggcgt gattgacagt tctgtggtct cgaccaaaac acttcggcat
     3901 catgttcggg catggggcgg cagccagtgg cgatggagga cacctcgcgg cggacgtcat
     3961 cggcggctgc cgcgtaccgc acggatcacc tcggcgactg ccttcaacac ctcggcgcgg
     4021 gcgcacgcgg tggtgtcctg caccgcaacc acgacgatca ctacggcggc gatagccgcg
     4081 atcagcatgg cgaccaccgg aaccaagacg acccaggcag taatgtccat ggaattccct
     4141 ccgtccgtgc cgccgtctgt cgagcggcac agcaaaagga gacaggagcg gcaaaagaca
     4201 gtcacgagtt gccggaccga ccggatcgtg gcagtgaaca gccaggtcac ggccgagccc
     4261 accactccgc ccgccggact cgccggacgc gtcacaagag ggagggcgcc cggtgagcga
     4321 gccgatccag ctgccagtcg gccgacgggt cctgcgcgat gaactacgga tgctggaaag
     4381 gaaggcactt cagcgcgagg gcaaaaaccg tacggacgcg atcgagaagg caaacgcaca
     4441 gttggagcca ctcggcctac cgaagctcaa gaccagcacg gtgagcgact ggatcgaaaa
     4501 gggcaatccg gcgaagaact tcctagtgct gtgggccttg gtccgggtgt tcctggagtg
     4561 gtcggggggc cttccaccga agggagccac cacccccaag gaccccgtcg gtgccaaggc
     4621 gaaggcagcc tggaactaca ccgaggaagg gtggcggctt cggtgggagg atgcgaagag
     4681 gtcccgcccc ccgactcccg cgccggagaa cgcacggctg ctcactgcat acctgcgggc
     4741 ggcacgcgac gccgccggac agcaccctta tcgcagcacc cgccaggacc tcaaactgcc
     4801 cgcgctggcc gacgtctacg tgcgccagca cacccgcacg cgcgcccagg gcaacgaggc
     4861 ttccgccgcc gttcccgccg cccaagtctt ccgtgctgac cacagcatct gtctgctcct
     4921 aggcgctccc ggcggcggca aatccacgct gctgcgcacc cacctcgctc agaccgccga
     4981 ggccctgctc tccaacacgg ccgagaagac gatcccgatc ctcctcagag cggctgccct
     5041 caccaccacg gacccgctcc ccgcagccct cgcacgcacc gtcaccgccg accttcagca
     5101 agacgggctg ctcgacgagt tgcccaccgg attcttccgc cgccctccac gtaccggggc
     5161 gtcctggcta gtgctggtcg acggcctcga cgagatcccc gacaccgaca cccgtagtgc
     5221 cgtgatgacg aagctggcca acgtctccgc caacagcgaa gggctgtacc ggttcgtcgt
     5281 agcgacccgc cccttgccgg cacaggaact cctcaagctc ggcgaccgcg ttgcgcatta
     5341 tgaactgcag ccgttctccc acgacgacct gtacacctac gccacgcact ggttccggtc
     5401 cctggacaat cccaggcgcc acaccgaagc gtttattgcc gggctgacgc actccggcct
     5461 ggaggtcctg gcccgcaccc ccctgatggc actcatgctg tgccagctct acctgaccga
     5521 tcccacgcgc cccctgcctg ccggccgtgc cggcgcgtac caggagttcg tcaagtggat
     5581 ctacgaacag aacacccaca agaacatcaa gaacacccat gatcaggcga ttcgccggct
     5641 gaaggaccgc caccagatcc ccgaggaaag cgacgccgcg gaaagcgctg ccgagcaggt
     5701 acggcagcac ctgcgggggt tgatcgacca cttggcctac gaacggctca atggcagacg
     5761 cggtgcggcc gtcgacatct tggcctcaca cctgcaggtc aaccggccgc gggaggtaga
     5821 gcagcatctg tggaacgcct tccttggcga cctcatgcgg cccaccggca tactgaccca
     5881 acacggggat gacttcgact tcctccacca gacgctcctc gaataccgtg cggcccgtca
     5941 cgccacccgc aacgaacaga cctgcaccca gcttctcaac gacctgatcg cgtcctcgac
     6001 cgttcgctcc gacggccgcc tagggcctgt gtggagttgt gatcaaggct gtgatccgag
     6061 gtgtcggatc cagaggaggc cggcacataa ttcgagtccg gcctggtagc tttcaggctt
     6121 tttgtcgtag cggacggcga ggccgcgcca gtccttgatc ttgttgatgg tgcgttcgac
     6181 gctgttgcgg agcttgtaca actgcttgtc ccaggtgacg ggccgcccgc cgcgtgagcc
     6241 gcggttcttg cggtgggcgg cctgatcctt cttctcgggg atgaccgcct tgatcccacg
     6301 cttgcgcagg tgagaccggt tctggcgaga cgagtacgcc ttatcgcccg cgactgcgtc
     6361 gggccgggtg cggggccggc cgaccgggcc ggggacgcgg atcatgttca ggacggggat
     6421 gaactgcgga ctgtccccgg cttgccccgc agtgatcttc agcgagaggg gcaggcattg
     6481 cggcacacag gaaaggtgcg tcttggtggt cagtccgccg cgggaacgtc ccaggtcagc
     6541 ggcggcgagt cgggccttgc ggcgacgcct cacgcgtcgt cgttcttccc gctccgggtc
     6601 cagttgcccg tcttgttcct ggccggcgcc cctttttctg cggcggcctt ctccaacgcg
     6661 tccagggtct cgggctccac gatcatcccg gcagcatcat gatgggcccg gactgtggtc
     6721 gagtccacgc tgaccagcga caagtccacc aggccccgct tcgccgcctc ggcgatcgca
     6781 ccctggaaca ccgcggtgaa caccccagca tcccgccact gccgaaaccg gccgtaaacg
     6841 gtggaccaat gcccaaaacg ttcgggcaac tcccgccatt tcgccccgtt cctgaaccgc
     6901 cacacgacgc cctcgaagtg cgcccgcagg ttctccgggt acggcccgta ctcaccgacc
     6961 ggcagaaacg gggagacgaa ctcccactcg gcatccgaaa gttgaggtcg agacacccca
     7021 ccgttttacc ccaaggcccc cgaccctccc gggccggggg cccacgagat cacaactcca
     7081 cacaggccct agcaccgccc gcagtcgccg actcctacct cggcttcctc cttgacgggc
     7141 tcagcgcctt ccacggccgc atcgccgccg agaccacccg atatgtggtt gagataatgc
     7201 agcacggagg tgaaggcacc catcggttcc tcaccaccca ggtctatctg aagaccaact
     7261 tgcccccagg ccccactgcc gtgtgtctgg cccggctggc tgacaacccc gccctggacg
     7321 gcctcgcgcg tgtgacggcg gcgcgggcac tggcggaggt ggacagcaat gccggcgccc
     7381 accacctggc ccgcctcgcc gacgacccca ccctcaacga cggctcccat ctggaggcgg
     7441 cgcgggcact ggccgaggtg gacagcaaag ccggcgccca ccacctggcc cgcctcgcca
     7501 acgaccccac cctcaacgac gacttccgtg tgcgggcggc gcgggcactg gccgaggtgg
     7561 acagcaaagc cggcgcccac cacctggccc gcctcgccaa cgaccccacc ctcaacgaca
     7621 gcttccgtgt ggaggcggcg cgggcactgg ccgaggtgga cagcaaagcc ggcgcccacc
     7681 acctggcccg cctcgccaac gaccccaccc tcaacgacag cttccgtgtg gaggcggcgc
     7741 gggcactggc cgaggtggac agcaaagctg gcgcccacca cctggcccgc ctcgccaacg
     7801 accccaccct ggacgacttc tccagtggaa gggcggcgcg tgttctcgcc cagacggagg
     7861 cgagagggcg cggtcggtga ttctgtgcac gcaccgtgcc cgcgacggtg tagcggcaca
     7921 ttgcgccctc gcgtttgctg cggctgcctc cgttcagtct cgtacggcag tgacggcaac
     7981 gcggcgcagc aggtgcgcgg tgggcaggcg ccgacgagcc tctccctgca gtccggcgag
     8041 tgccgaaccg ggctcggcgt gcagggtcag cgcggtgcgg tagatcccct ggtaggcgtc
     8101 gtcccaggcc ggggtgctgg tgcagtgcac gtcggtgaag cccgccgtgt gcagcacgcg
     8161 agtccagtcg gtgtgccggt ggcgcggtgg caggcgctcg tcgccggggg tgtgcgggtg
     8221 ccagccggtg aggaccagtc ggccgccggg cttgaggatg cgcaggacct ggcgggcggc
     8281 ggcgacgcgg tcgggggcgt actgcagggc gtccagcgac agggcctcgt cgacgcattg
     8341 gctggtcagg gggaggaggg cgaggtcggc cacggcgaag gccgcatcgg ccgcgaacgg
     8401 tacggcccgg tggcgggcct gggcgatcgc gaccggggaa aagtcgatgc cgaccagggt
     8461 cgcgtgcgcg cggccggcga gccacaggcc gggaccgccg cggccacagc ccagatcggc
     8521 caggatctgc cgggggcgca agtcgagttg gcgggcgagg tggtggagca ggtcggcgca
     8581 gaggaaggag aacaggtcga ggtccggcgg caggtccggg tcgaccaggc gcgcgatcgt
     8641 gctgaaggcg ctgccatgtc cctcggttcc ctcggtgccg aagaggcggt cgaactccaa
     8701 cgcactggtg gtctggtggc cggcggtgtc ggccgcgcgg ccggcgggtg gtgtgctcat
     8761 gtcctactcc ccggggcgac cgtgatggtg atctggcgca ggatctggtc agcccgctcg
     8821 tcgacggtgc gcggatcgtg gccggtgacg atgacatggc cgaggcggcc gcggttggac
     8881 gtcgccggac ctacgtccga gccctcggcc gcacgcacgc gtacggcggg gatggtggtg
     8941 gtcaccgctg gcaggccggt gacggcgacc agccgtcccg catggtgagt ggtcaggaac
     9001 cgtacggtgg cgtaaccgcc gggtgcctgt gtgatggtga ccggcctgcc gagggcgatg
     9061 tcccacacgg tgcgccacgg gtcgatgccg agagcgtgct gcatcaggac gccgatgtgc
     9121 ccggcgccga gtcgggcgcc gatctccagg acggtgcacc ggccgtcggg gctgaggacg
     9181 agttcggtgt gggtggcgcc gttgcgtacg ccgactgcgg cgatcgcccg tccggcctgt
     9241 tcgagtaggg cccgctcggc ggccgcgggc aggcgggcgg gcagcgtgtg gccaagttcg
     9301 acgcggtgga tgccgctggt ggtgtgcttg cgggtgatgc acagatgggt ggtgacgtcg
     9361 tgctgggtga tgtactcgac gctgaactca cgtccctgga cgtgttcttg gaccaggatg
     9421 cgctcatcgc gcagcatgcc gtacatcacc ctggccgtcc gggcggcatg ccaggccggc
     9481 tcgagctctt cgggaccggt gaccacggtg acgccggccg atccggcgcc gtcggccggt
     9541 ttgacgacac acgggaagcc gaccgccccg gcctcgtgca ggccccgcag ctcacgcagg
     9601 tccgcgacgg ccttggtgcg gggcatggtg acgtggccgg cttcgaacgc ggttgccatg
     9661 agggccttgt tgcgtgcggc ggcggcgcgt tcgggatcgt tgcccggcag gccgagggcc
     9721 gcgcacgatc gggcggccac ctcggtgagg tactcgttga cggtgagcag ggccttcacg
     9781 ccgatccggc gcccgtagcc ggtgatgtcc gcgacggctt ggccgggccg ggtgaagccg
     9841 gtgacgaggc agccctcgag gagctggcgc agctcgccgg agtagctggc cagggtggcg
     9901 gcgtccgtga cggcgtgcac ggggtggccg gcggcggccg cggtccgggc gagtgcctcg
     9961 gactcggggc cggccgcctc cagcagcatg accggcacgc tcaccggtag tccaccaggc
    10021 cgcccgcgcg gtgcgtgtcg agggtgaagc agtggaatcc gccgccgaag agcctgcggt
    10081 gccggtgctg gaccgggatc acggtgaagc cctcgttctc cagggtcttg atcaggccga
    10141 ggcagtcggc gttgaccagc acccgctgct cgtccaggga cagcacgttg atgtcgatgt
    10201 acgggctggt cagcagcagc tcggagtctg tgtagacggg gaactggccg ggctccggtt
    10261 cgggcggcac aatgaacgtc catgtccgga aggcatccgg gaggatctcg cgcagcccgg
    10321 cgtgccgggc gaggaacact ccgggcttga ggaccaggag catggagtcg atgtggttgt
    10381 cggccatccg gtacacggtg tgcacgcgga agcggccctc cacgtgccgc ttcagccagt
    10441 cgaccgcgag ccggtggttg tcttgcgcga cgttgacgat caggtcctgg cccaggcgca
    10501 gcacctgcgc cccgtcgagc atcatctcca cgcccacgtc gtatgggctg ggctgtgggt
    10561 cggtgatcgg ctcggtcggt ccgcccaggg tggtggctgc ggactgggcg tagctgaggt
    10621 cgaaggaccg gtcggtcagg acggggcggg gcatggtcgt ccagcgggct ccggtgtcga
    10681 agtaggagcg gaagacctgg ctgaggagcc gggtttccag gtagcgggag cggaccgccg
    10741 gcggcgtctc gatgatctcg tcgccgagga cgagggtgtt gtcccgcacg ttgagggctg
    10801 gggtcggggc ggcctgccag cccagcccgg cgatcggtaa ggcgtcggtg ggcagcggca
    10861 gcggccggtg cacggtgatg ccgagcgagg tgagcgtggc ggcgaggttc tcgacgtcct
    10921 cgtggagctc ctccgtgtac cgcttgccga tcttccacgt ctcggcctgt tcgctgccgc
    10981 cggcggccag gcgcggatag gcccagtcgg agcggtagcc gccgatggcc acgtggaaga
    11041 acaactcgaa ggtgaggtcc cggtcgtgcc ccacgtagtt ctccgcggac cccacgatga
    11101 tctcgctcag cggggtgaag tcgtcgtagc tgttcagcgt gcgcattgcg tcctcgattc
    11161 gtcgtgtcag gcgccggccg ggctgctgtc ggcggccggg agggaaacgt gctggctggt
    11221 cagggcacgg ccgtgccgtg cgtggagcac gacgtggtcg ttgccgagct ggagcgtgcg
    11281 ctgctcgctc cagccggcgt agcggtactc gccgtcgacg acgtgcacca gggcgaagcc
    11341 gcgctcggca tgggtgagga ccaggtcgcc gtcgcgctcg gtgagccgga ccggcacggt
    11401 ggggccttcc agcggggtgt cctggctgaa gtcggtgaac ccggctggca ggttcacggc
    11461 gcgcggcagc ggtgggctcg gccggagggc cgggtcgggc agccggttga agaggacgtc
    11521 ggcgtagccg agcgactcct gccactcggt gggaaacagg gtggcgagtt cccgggtgaa
    11581 cagcgcgtcg atgaccgcgt ggaccctgcg gacggagccg gtgttggcga ccatgtgctc
    11641 gcgggagaag tcgccgtacc agaaggtgcc gggctgccag cggtgttcgg tgccgtccag
    11701 gacgaggacc gcgccggggt gggtggcgat cgggatgtgc aggcgcacca tgcctcgctg
    11761 aagcgcgtat ttggggtcgc ggtgtggctg ggaggcggcg cccgggccga gggcgagcag
    11821 ccgtacggcg ttcagcgggg ccgggatctc gtcaaggatc tcgcggaggt acggcatctg
    11881 gtcgagccag cgggtggcgg cgtactggtc ggggccgggg ccgcccgggt cggtgcgggt
    11941 cgggtcgccg ccggggctgc gcagcggcag cacgcgccag tcggtcgggg tgtccgggcc
    12001 gatgcgtccg gcggcgtagt gggtgcgctg gcgctgccaa ggatggccgg tgaccgcgga
    12061 gagttcgtgc gcgaggcggt ccgcgtcgaa ggccggggtg aggggggccg ccggcgccgg
    12121 ccgggcgggg gtcgtggtgg tcatctggcg agtgccttcc tggagtcagt ccgccgcgcg
    12181 gtggaggagg tggtggtgaa ccggtcttcg agggcgtgcc agatcgcgtc gcggtcggcc
    12241 gggctggcgt ggacggtgga gaacgtgaac tgcgccccga gggagggatg gtcgacgatg
    12301 ggcatcgaca cgatcacgcc gctgcgggtg gcggggtcgt agccgagacc gagctcggcg
    12361 agcgcgcggt ggaaggtcga gccgtcgggc aaggtccact ccggcggaat gtgggattcg
    12421 gtgacggtgc gctcgggggt ctcgttcgcg tgcacgatgt ggtgggcgaa gacctcgtag
    12481 atgtgccacg agccggagac ctgggcgttg acctcggtga acagcagccg tccgtcgggc
    12541 cccacgatcg cgtcggtgct gatgcggccg cggtagccaa cggaccggta ggtgtgggcg
    12601 aggcgggcgg acccgtcgag cagctgctcc tcgacggccg cggacaggtc gcgcaggggg
    12661 acgctttcgt ggctgaggcg ccggtcggtg tagcgcagtt cgccgcgctc ggtgggctgg
    12721 gtgccggtct cggtgaggtg ctgctcgcag tagaccgtga aggcacccgg gatgaactcc
    12781 tccaggacga cggggaaccg gccgtcggcg gaggcccacg tccagcgctc gcgccagtac
    12841 gcggcggccg ccgcgggaag gtccgtgcgg cccaggtggt ggaggtgacg ggcgcccgcg
    12901 tggccggtgg ccagggtggg atcggtgacg agcagctcgt tgcccacccc ggccccgttg
    12961 tgtgcctgtt tcacgaccac tgccccgctg cgctgcagca gggtcagggt ggcggcggcg
    13021 gcctcgcccg ggtcgcgtac gacggtgccg gctgccaccg gcactccggc cgcggccgcg
    13081 agcgtgcgga acacggcctt gttgttgacg agttcgccgc cgccctgggc aaggaagtcg
    13141 cagccgggca gtttctcggt caggccgagg gcggtggcga agcgggcgac ggaggctgac
    13201 ggccacagtg cccagatctc ccccaccgcg tccgggccgc cgtgcttggc gaggtacgcg
    13261 cgcacctggt cgagggtgtc ggggtgggtg agcatctggg ggtcgagcag gcggccgccg
    13321 taggcgccgg tcggcgccac gaccaggtgc agccggttcg ggtcggtgcc ggtcagcgcg
    13381 gtcgcgtacc gcaggaagtg ggggtccggt ggggcgcaca ggacgaccag gtcgccgttg
    13441 cgcgcacccc acagggcgcg ctgcgtccat gcccgcaggt catggcggtc gcggatggcg
    13501 gggtcgatgt ggttggcgat gatgatcctc aacgcatgct ccaggtcggg aaggtgacga
    13561 ggcgggtcag ggctggaggg tgacgggcag atggtcgaag gcccgcatgg tggcggtgtg
    13621 tcgtcgccgc gcggggccgg ccgggtgcag gaggcccggg tggtcggcga gggcgtcgag
    13681 gagcgcgacc aggacgcgct gggcgagggt ggtgccgagg caggcgtggg tgccccagcc
    13741 gtatccgagg tgccggttcg gcgagcggtc cagcaccagc cggtccgggt gctcgaagtg
    13801 cgcggggtcg cggttggcgg cctggaacag caccgtcacc ttctcgccgc ggtgcaccgt
    13861 cctcccgccg agcaggacgt cggtggcggc gagacggctg gtgccctgga cggggccgtc
    13921 gtagcggacc agttcgtcga cgcccgtggc ccgcagctgc ggcgtctcgc gcagtgcgcg
    13981 ctgggcctgc gggttgcggg ccagcgtgtc gacggcgttg ccgatcgccg cggccagggt
    14041 gctgtatccg ccctggaaca tcacgcgggc cgtgtgcacg acgtaccgtg cgagctccgg
    14101 gccggcgtcg gccgtacggg tacggacgtg gccgagcagc ccggccgggc tgccggtggt
    14161 ggtgaaccag gaggccacca gttcgctcag cttctcccgc gcgagacggc cgggctcgac
    14221 aaggtcgggg ttgaggcctc catccatgct ccgcatgatc gtgtcggata cctgcaccca
    14281 tgcggacagg ggcggcgggg tgaccccgag caggtcggcg atggcgtcca gggcgacggg
    14341 ctgggcgagt tcacgcatca cgtcccacgc cggctgcgag gcaagaacct ccagccgggc
    14401 cgcgatgtcg cgtcgggtcc gttcctgcag cacgggcagg tcctgcgcgt gcagcgaggt
    14461 catgaaggcc gaccgcacgg cggcctggtg gggcgggtcg aggacctgca cgctcagcga
    14521 ggcctccggc accgtgcggc ccagccgcct ggggtcacgg gcgaaggcct cgtggtcccg
    14581 cagaacgcgt acgcagtcgt cgtagccggt gaccagccag ctttccatgg tgtcgtgcca
    14641 caccaggggc gcctgcgcgc gcagcgccgc gagcacggga tacgggtcgg cgagggtggc
    14701 ttcgtccagc gggtcgtacc gcaccgggca ggtgggcgtc acggccacgg tggtctcctt
    14761 cacgcggtag aaggggcgga ccggtcccgg ccaccgacga gacgtcggcg gccgggaccg
    14821 gaacgggttg cggagcacga tgtacatcag tggtcgtacg tcatggcgga cccccctttc
    14881 ggcctcgggc gggacagccg cggtgtgctg cgacatcatg agaatgggct caactgttcg
    14941 agttcgtcga ccagttgagg ggggtcccgt gggggtcccg ccttcgtgaa ggagtcacca
    15001 gtcctgtgcg ctgagtgatt ggatggagac gtggaagaga ccaccggtca cccgttggtt
    15061 gtggcgcgtc atgcggccgg caagacgatg gaggagttcg tctccggcat ccatgcctcc
    15121 gccgctcggc ggaatctgcg ttcaggcatc gacgaagcac gggtgcgcaa atggcagcgc
    15181 ggcgtccaac ccagcgagga atcccagatc tacatcgccg aagcactcgg ctggcctgcg
    15241 gacatcgtcc gcgccgacga ctggccgaac tggctgccgc tcaccgccaa cggggtagtc
    15301 cccctcggcc cccacagctc cgtgcccgcc ctgagagagg cccagcgaac agcgatggaa
    15361 cgccgcacct tcctgacgat ctccggcgcc gccctgtccg ccctggccgc ggactgggcg
    15421 ggcggccccg cagacgcgct cgcccaagcc cacgacggta aacccatcgg cgaagacctc
    15481 gtcgccttct tagagaactc cacccgacac ctcgccggcc tgtccaccga gcagcgacag
    15541 cacacccccg cgctactgga cgcccacctc gccacggtga ccgaactgct cgaaaacggc
    15601 cgctacacgc ccgccctcgg gctgcgcctg cacaccctgg cggcctccct ctcccagacc
    15661 gtcgcctggc acgccttcga cctgggccgc cacacacatg cgagccagag ctgggtcgca
    15721 ggcctgcaca acgcccacgc cgcaggggac catgacatgg gcgccggcct cctgggcgat
    15781 ctcgcctacc aggccgcctg gcgccgcgat cacatcactg cggccagcat cctcggccac
    15841 gcactgaccc gcgcccagaa ccccgccgcc cgctgcctgc tccagctccg cctcgcccgc
    15901 accctcgcag cacgcggcga ccgcagcgaa cgacgcgccg tgctgcgcgc cctcgccgcg
    15961 gccgagaaac acctcaacga cgctggcacc gaacggcccg cctggtgcgc atgggtgggc
    16021 gcagcggatc tcgcggtgga ctccggccag gccctcctgg acctcggcga cactgcccgc
    16081 gcccaccagc tcatcaccga aggcgaacgc ctgctgccca cagctaggga caagacccgc
    16141 ggcgtgttcc tcgcctaccg cgccgcgagc tacctcgacc tgaaggaacc cgaggccgct
    16201 gcggccgccg ccacccagtc cctactgctg gcccgtcgca tcggggcacc ccgctgcgta
    16261 cagctcgtcg acgacctgct cccccgcttc cagccctacg cccgtgccca aggcgttccg
    16321 gaactcctcc agctcacagc cgcatagacc gttctcctcc aggtcgggaa catcgctcgc
    16381 gtccggggat cgggagcccg tcgctgagga gctgtgttcg tacccgcgtc cgcggggacg
    16441 gtcttgcctg ccgtcccacc acatggagaa cagcatgagc gagttcgctg gcgccaccta
    16501 ccggcccggc atccccgagg ctgccgtccg tctcgtcagc cagacggtcg ctgccaagca
    16561 gcacccggtc ctcctcgacc ttggatcggg cacagggcaa gtgcccgctg ccctgctcga
    16621 ggccttcgct gagattgacg tcgtcgaaag ggaccccggc atgcttgcgg aggccgagac
    16681 cagccggccg tgctgtcgct gctggacggc tgcacggcca aggacgccac tttcgtcgtc
    16741 atgggggacg acagcctctg gacggcccgc tcggcatgga cggacgccca gcggtccctg
    16801 atccaggagt acaccggcag cgaccgccgg gcgggcaaag acaggaccta cgctgatggc
    16861 gattcttgaa atcggccggg gatgctcctc acctcactcg ctccgctgtt caaagatgtg
    16921 aggagcttca gcgagcgtcg tgcccggtct tcggccggcg cccgctaatg gaggtgcggg
    16981 ccgggttgag ccgtcaagga cgcctgcggc ggccctgcga agtggggtcg cccatcctgg
    17041 actgctcgcc ccgctcctgg acttgggtgg catcgggcag ccccctccac tgtggcgtcc
    17101 ggcccgggtc tgacgtacgt cgccgcccgc tgcgacgaag gcttcggcgt ccggccgggg
    17161 cctgcttggg tgtcagcgga ttcagggctg acgcgccgcc tcgtgcagtc ggtcacgtgc
    17221 ggccctcagc aagccctgcg accactccgc acgggtgact ccctcgggca gtctggtcaa
    17281 ctcggcgtgg ctggcgccca gcgcgcgggc ggtcgcctcc accgcgagac cctgcataag
    17341 atcgtcgttg tactcaccgc ggccttcctc ggcgagcttc agcagggcgc ggaggagttc
    17401 agcgtcgaac ccgtcgtgca ggatccaccc agcccccgag accgcggcca tgaacacgtc
    17461 gtcatccagg tcccactcgg gggatcccag caactcgagg atctgcttcc tgtacttcgc
    17521 tcccactctc cagtgcgcgg tgagcacctg cacggcgagt gccgagacct cgggatcctc
    17581 ggggtagatc agatacgcgg cgatcagcgg ctcgtatgcc ggaccgcccg cacgggccac
    17641 cgcatacagc cgctggtaga gctcccggcc ggcccggcac tcggtgacgg cttgagcgat
    17701 ctgtttcacc tcctgcggcg ggatggtgcc gtccttcgcc cgtgcgatca gctgccgcac
    17761 atatgcatca tgcgccactg tcatgctcca ctcacttgat tctggggacg aactgctcgg
    17821 agaagtccag cattctgctg gcccgcccca ggtcggcgac gagaaggtct cgcatggcgc
    17881 cactcgtccc aggatgggcc agcttcctgt tgattgcgga aggggcgcat cctcagcaac
    17941 ggcgactatg cggctcgata gaggccgcgt tttactcgca caaccttccc catcttcagg
    18001 agcccatcga gatacacgga ggcgccgtct ggcttcagga ccgaacccgc cgcagtcacg
    18061 gtgtccgcga tctgccccag cgtcatgggt tctgaggact gggcgagggc agcaacgatg
    18121 gcttccgcct tcgtcatccc ctggacgttc agctccgggg ccttgacgat cagcccctcc
    18181 agcgtcgctt ccttggcccg cagggccgcg atttgagctt cgagccgctg agattcgagc
    18241 tcggcggcag ccagctcaac cctcacctgc ttcaggtcat cctcgagtgg gttcatacat
    18301 gcaaccttac aggaatctaa gaatcattcc tagctgccta agattatttc ttagagcttg
    18361 ctagatcgtc ggtcgaggcg gcgacaaggc tccgccaatc cctgcggtgg tagttgagtg
    18421 acgtcccgtc ccaggtcaga tgccgtatga gtggggagac gcgtggagca ggtatggggt
    18481 cacccccgag cagggggtgg ggattttcaa ggagcgtcat caacgcggcc ctcggccgcc
    18541 cctaccggga aaacctcgcc gagtccgtct tcgccgctga gcttgactct gtcggtgatc
    18601 ttggagtttg ccggtgcggc agcatgatcg gcgggcatgc tcgggtcgtt ccgccgaccg
    18661 atgcagttgt cgaggtgtct gttgtccctt cgcccccgtt ccggtgagca agtcccgtct
    18721 ctgaccgtgc aggttgcgcg ggcgagcaac ccgggtggta cgacggcgat atgggtgcgt
    18781 gaccggctgg acgggctgtg gtgcgacgag gacttcgccg actggtaccc gcgggacggg
    18841 cggccgggtc tctcgcctgc tcaactggcc accgtctgtg tgctgcagtt cctgctgggt
    18901 ctgtcggacc ggcaggcggc cgaggcggtc cgctgccgca tcgacttcaa gtacgcgatg
    18961 gccatggagc tggacgatcc cggcttccat cacagcgtgc tggccgactt ccgcgaccgc
    19021 ctcgctgaag gcgaccgtgc cgaccgtctc ctggacctcg cgctggctcg tctcaaggag
    19081 gccggactgg tgcgcgagcg caccacttag cgcaccgact ccacccacgt tctggccgcg
    19141 gtgcgcgacc tgacccgcct ggagctgatc accgaggccg tccgcgccgc actcgaagaa
    19201 gtcgccggca catctcctca cctgctcgac gagttggtcg atgaggactg ggggctccgc
    19261 tacggccgac cggtccgcct gggcaagaac cccacccggc ccaagaccag gatcctcgcc
    19321 acgggaaacg acgccgtccg ggtcctggaa cacctctacc ggcacgggac agaccacacg
    19381 ttcggccctc gcatccaggc cctgcggcag atcatggtgc agaactatca ccatgacggc
    19441 gcaggacacc tgcgctggcg caccgccgag acggaaggcg accccgggct gccgccctcg
    19501 tccctggcgg tcgtctcccc ctacgacacc tcggcccgct atgcacggca cggacacatc
    19561 atcagctgga aggggttctc cgctcacctg accgagacct gtgctcccga cggccccaac
    19621 gtgatcacgg acgtggccac caccgcggcc accacccacg acagccaggt cctgcccggc
    19681 atccacaccc gcctcgcccg ccgcggactg ctgcccgccg agcacctggt cgacgccggc
    19741 tacacctccc tgccccacct ggaacaagcc acccgtgaac accaggtcac cgtctccgga
    19801 ccgctccgga gcgaccccac ccgtcagcac cgccggaacg agggcttcgc ccgggacgac
    19861 ttccacatcg actacgaccg tcagcaggtc acctgcctcc agggacaggg ggttggcacg
    19921 gcccctaccc gacctcctct cccaccgcgg ccccgctgat cgtggccagg ttcgccaaga
    19981 gccagtgccg cccctgcccg gcccgcaccc agtgcaccag caccgccgac agcgcccgca
    20041 ccgtgggctt tcccccgcga gagccccgcg acctgcaact ccgcgtccgc gccgagcaac
    20101 agacacccga gtggaagact cgatatgcgg tccgctccgg agtggagggc acggtcaacg
    20161 agttcgccca cggacatggc atgcgacgct gccgttacag aggccaggga aaggcccaca
    20221 tccagcacgt cctgacggcc atcgcagtca acatcgagcg cctcagcgaa ctgccaccga
    20281 ccgaagaaac acccacgccc cgccggccaa ccgcccttca gaactacctc gaccagcgtg
    20341 agatacgccg gctgaagtcc tggcgaaccc tgggcagcta acctcggcac tccaagatca
    20401 ccgacagagt caagctcaga agctgtgtca catcctcttt tcgcaggtca cggggtcgtg
    20461 acgcgcggca gtgatcccgc ttgacgttgg gttgggcatc gatgggcagg cgcccgaacg
    20521 gcaatggaag gatcttcagg cggctgcgag aggctgctca actggctagg agagcgatca
    20581 cggccatcat gggcggcagg gaaacggagc tcaccagaga tgaaccccgg tgaccttctg
    20641 cataccttct ccatcgatct cgtcgccgaa cggcacggtg acctggtgac gcctgcgcgt
    20701 caccaccagg tcaccgggtt gttcgtgggc tacgggcgaa gggcgataaa attacccaaa
    20761 tcggtggctt ggcttccggg cccaggctgc cgctcgacct gtgcgaggga gcggcacggt
    20821 ggcgaggtct cctcaggaac gcggagtccc gcacagcgcc ggtgcgcggg acaggttgct
    20881 gcccgtgctg cctgctctgc tgctgttcgg cggcctgctc ttcggcctct tcacaccccg
    20941 cgatgtgagg ccggatgcct tcctcgccac ggccatggtt tctgccgccg cgctgctgtc
    21001 cctgcggggg accgtgctca ccggagtggg cgcgtgcgcc atctttgtct gcctgatggt
    21061 ggacttcaat gggctgcggg atgcgaccgc ctactctgag ctggccaccc tcgtggcgat
    21121 tgcggcattc gccgtcttct tcaaccgtct gctgggccga cgtgcccatc agctggttca
    21181 ggtccgctcg gtggccgaga ccgcccagct ggcggtgctg catccggtac cgagacacct
    21241 cgggcacgtc acgctcgaga gcctctacct ggccgccgcg gcggaagccc ggatcggcgg
    21301 cgacctgtac gaggcgatac gcaccccgca cggcgtacgg ctgctcatcg gcgacgtacg
    21361 cggcaagggc ctgctcgcgg tgcggacggc cgcgacgctg ctcagcgcct tccgcgaggc
    21421 cgcccacgac gcgcccgacc tgccccacct cgcgtgccgc ctggagacga gcatgagccg
    21481 ccacgcgtcc cagtacccgg gggtcccggg ctcggagatc gctgaacgct tcatcactgc
    21541 gctcctcgcc gagatcccgg acgacgaacc ggtcgtccgg accgtcacct gcggccaccc
    21601 gcccccgcta ctgctgcacc gcggcgaggt ccgggaactg cagcccgccg ctccctcgcc
    21661 gccgctcaac ctgggcatgc tgatgagcga cgggtaccac gtcgacctcg cccccttcca
    21721 ccccggagac cagctcctgc tgtacaccga cggagtcact gagcctggat ccaccggctt
    21781 gatgtctgtg gacagtttct cggggaacga agaagtgcct tgtgacctgc gatgatgggg
    21841 tttctctagg accacatcag gcacgatcag caaggcactt ccgagatgca atcttcccat
    21901 gccgcagcgg cggtctcatc cgcgttcgac gacccgaacc taatcgcgta cggcggcctg
    21961 gagccggtgg tgcggttggc cgagcggtgc ggtctgcccg cactggtcgg ggagtacatc
    22021 cgtctgccgg cctcgaagga cggcaccggt gccttccccg cggcgaaagt gatgtcgctg
    22081 gtgggcggca tggtcgcggg cgccgacagc atcgatgaca tgcaccggct acggcacggc
    22141 gcgatgggcc gcctgttctc cggtgtgcgg gccccgtcca cgctggggtc gtttctgcgt
    22201 tccttcacgc acgggcatgt gaagcaattg cacgccgtgg cccgccggtt ccttcccgaa
    22261 ctggcccgtc acgccccgct gctgcccggc gcggaccagg tcgcctacgt ggacatcgat
    22321 gacaccatcc gccgcaccta cggctacgcc aagcagggca ccggttacgg atacagcaag
    22381 gtcaagggcc tgaacgcgct gctcggcatc gtctccacac ccctggccac cccggtgatc
    22441 gccgccacga ggctgcgcaa gggaccatcg aactccgcgc gcggggcggc agcgttcgtc
    22501 gccgagacca tccgcaccgc ccgcgcctgc ggcgcgaatg gcctgctggt gatgcgcgcg
    22561 gactcggcgt tctacggcgc cgatgtcgtc aactcctgcc gggcgctggg cgcgcggttc
    22621 tccatcaccg tgcggatgaa cgcttccgtc aaggccgcca tcgcccgcat cgatgaggac
    22681 gcctggatgc cgatcaagta ccccaaggcg gtctgggacg aggagggcca gtgctggatc
    22741 tccgacgccg agatagccga gaccggctac accgccttca cttccaagcc gaagaagcag
    22801 caggtcaccg cccgtctgat cgtgcgccgc gtcaaacgcc tgagcactgg caccgtcccc
    22861 gccggacagg gcacgctgtt tgacacctgg cgctaccacg ccgcgttcac cgactccccg
    22921 ctctccttga acgatgccga gcgtgatcac cgacggcacg ctgtcgtcga gcaggtgatc
    22981 gcggatgtca agaacagcgc cttcgcccac gcaccctccg ggcatttcca ggccaatgcc
    23041 gcgtggctcg ccctggccgc cctggcgcac aacctgaccc gcgccgctgg cgcactggcc
    23101 ggcacgttcc atgccagagc gaccaccgcc accatccgtg accacctgat caacgtgccc
    23161 gcccgcctgg cccgctccgc ccgccgcctc accctgcacc tgcccgaacg ctggccctgg
    23221 agcacggact tcacccagct cttcagcatc gtgcacgcgc caccagcccc ctgacactcc
    23281 ccgaccgacc tgcccgaaag ggcccgagaa ctgcggaaaa gtggaaaggc tgggcagacc
    23341 agcgaccacc ccacgcccga atccgcaact cagccccgac acgccctgca cgaccccgaa
    23401 ccgatcacac cacaatcaag ccggtggatc cgggctgaga cacgcgaccg ctccggcacc
    23461 ttctaccccc tcgccgaacg catccgctca tggagcggcg aggcgcccca ccaactcctc
    23521 gaccatctcc ac
//
