LOCUS       NZ_CP041610            22649 bp    DNA     linear   CON 14-NOV-2023
DEFINITION  Streptomyces sp. RLB3-17 chromosome, complete genome.
ACCESSION   NZ_CP041610
VERSION     NZ_CP041610.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RLB3-17
  ORGANISM  Streptomyces sp. RLB3-17
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/14/2023 04:19:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,027
            CDSs (total)                      :: 10,924
            Genes (coding)                    :: 10,421
            CDSs (with protein)               :: 10,421
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 503
            CDSs (without protein)            :: 503
            Pseudo Genes (ambiguous residues) :: 0 of 503
            Pseudo Genes (frameshifted)       :: 178 of 503
            Pseudo Genes (incomplete)         :: 409 of 503
            Pseudo Genes (internal stop)      :: 52 of 503
            Pseudo Genes (multiple problems)  :: 128 of 503
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10308317
            Orig. end                         :: 10330966
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041610.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041610.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22649
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="38"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22649
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22649
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12649](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12649
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            <328..>469
                     /locus_tag="FNV62_RS56280"
                     /pseudo=""
     CDS             328..>469
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948548.1"
                     /locus_tag="FNV62_RS56280"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="cyclase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEHQTDVMLQVAYAPKGVAETAADKLGFVKRQIPGVLKVQVVHR
                     EP"
     gene            1028..3697
                     /locus_tag="FNV62_RS46350"
                     /old_locus_tag="FNV62_47025"
     CDS             1028..3697
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671000.1"
                     /locus_tag="FNV62_RS46350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47025"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_225900628.1"
                     /transl_table=11
                     /translation="MVLLVVAAVAAVVLQTARDAVQRGRRESVVAAQSFASAPGTAEAL
                     RSRDPTAVLQPRAEEVRKRTDVDFVVAMNTQGIRYTYPYPSEIGKKFVGTIAPALKGRT
                     VVEQAGGPPLPAGKGTAVQAVVPVTDSRGKVVGLVSAGITVKDVAALWLPQLPIILGSG
                     AAALALSMTGTTLVARRLRRQTHGLAPAELAQLYEHHDAVLHAVREGVLITGTDGRLLL
                     ANDEARRLLDLPADVQGRPVRELGLPEPITRLLSSPEAVTDEVHRAGDRLLAVNKRPTY
                     RQADRGGSVVTLRDTTELAVVSGRAEVARERLKLLYEAGVGIGTTLDVGRTAQELADVA
                     APEFADLVTVDLLDAVLRGWEPTAEGWRHLRRAAIGGEQPMIPVYPLGEVITFSRRTPQ
                     MRTLQERRVLLEADLRQAHGWREQDPERARKALECGLRSLVTVPLQARNVPLGVVNFYR
                     TVDSPAFQPEDLSFAEELAARAALAIDNARRFTREHAMAVTLQRSLLPRAQPDQDALEV
                     AWRYLPAEAGVGGDWFDVIPLPGARVAVVMGDVVGHGLHAAATMGRLRTAVHNFSTLDL
                     PVDEVLGKLDDLVLSMDNEENAGDAAEGHEGEGVTGATCLYAVYDPVSEACTMARAGHP
                     EPAVVRPDGTVTCPGVPASTPLGLGGYPFETAEFSLPQGSQLVLYTDGLVEDRTHDIDV
                     GMERLRQALDGSERRTPEETCQAVIDALKPSHSSDDIALLVARTRIFPPSRVAEWDVPS
                     DPAVVPSVRARCRETLREWGLEEAGFATELILSELITNAIRYGLPPVSARLLHGRCLIC
                     EVSDGSGTSPRLRRAATTDEGGRGLFLVAQFAQRWGTRYTTRGKVIWAEQFLHDGTSAT
                     PSRTPVDFLLDQFDDLDA"
     misc_feature    3814..3831
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.09"
                     /tool="antismash"
     gene            3832..3954
                     /locus_tag="FNV62_RS57270"
     CDS             3832..3954
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS57270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_258320975.1"
                     /transl_table=11
                     /translation="MGPAATTCSYLGQNRHNAFPSRLKELRAKHVSEHGMPFGS"
     gene            4362..4565
                     /locus_tag="FNV62_RS46355"
                     /old_locus_tag="FNV62_47030"
     CDS             4362..4565
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017238009.1"
                     /locus_tag="FNV62_RS46355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47030"
                     /product="cold-shock protein"
                     /protein_id="WP_143629568.1"
                     /transl_table=11
                     /translation="MAQGTVKLFNPDKGFGFIAPDEGGAYTFGHHSVIDTGGFCSLEEN
                     QRAQFTASRGPKGMHADRVRAL"
     misc_feature    complement(4366..4381)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            4690..5781
                     /locus_tag="FNV62_RS46360"
                     /old_locus_tag="FNV62_47035"
     CDS             4690..5781
                     /EC_number="1.14.19.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) delta12_cd03507"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381819.1"
                     /locus_tag="FNV62_RS46360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47035"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_225900629.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 4.4e-17,
                     bitscore: 61.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDITIRGTGPADHTDMAEPPPGGRGSDYAALSREVKQSGLLKR
                     RPGYYCVKVGANLFLLAAGWAAFALIGQSWWQLLTAAFLAVMFTQTGFIGHDAGHHQIA
                     ASKRVNNVLGRVHADLLIGLSYGWWINKHNRHHSHPNHVDRDPDIADGAIAFTQDHARV
                     RSGAYAWLARHQAWLFFPMLLLEGLALHIAGVRALLDRTGTATSRAAKLAEAGLLTAHL
                     GGYLAAVFLVLSPVQAVCFLVVHQGLFGLYMGCSFAPNHKGMPVFAKDDKIDFLRRQVL
                     TSRNIRGHRFTDFALGGLNYQIEHHLFPSMPRPSLRHAQELVRTFCARHGIAYYETGLL
                     NSYAQVLRHLHAVGGPLRPEMEY"
     gene            5958..6260
                     /locus_tag="FNV62_RS56285"
     CDS             5958..6260
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012472.3"
                     /locus_tag="FNV62_RS56285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_240361541.1"
                     /transl_table=11
                     /translation="MLSAIRDAFAILEEEVAAGRVAGYGVATWAGLEEAFTVGELLALA
                     AEAAGGQHHHLVAVQMPVSLVMMTPIARALHGRGPLPAAADVGLRVMASAPAAPR"
     gene            6271..6495
                     /locus_tag="FNV62_RS56290"
     CDS             6271..6495
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS56290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225900630.1"
                     /transl_table=11
                     /translation="MVGQEFADLIRPGLTPAQACILAVASCPGVTDVLLAASGAPHWRE
                     AADAVAQPSLTAAKLRESARHPSSFTYRS"
     gene            complement(6492..>6830)
                     /locus_tag="FNV62_RS46370"
                     /old_locus_tag="FNV62_47045"
                     /pseudo=""
     CDS             complement(6492..>6830)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026834.1"
                     /locus_tag="FNV62_RS46370"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47045"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELLPLLDKIPAIAGRVGRPRRRPDALPADRGYDHDKYRRLLRAPG
                     IRPVIAKRGEPHGTGLGIFRYVVERTIVWLHGFRRLRTRWERRDDIHEAFLGLAVCLIT
                     HRHVQRLS"
     misc_feature    complement(6828..6841)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    complement(6934..6949)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            complement(7251..7928)
                     /locus_tag="FNV62_RS46375"
                     /old_locus_tag="FNV62_47050"
     CDS             complement(7251..7928)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF041528.1"
                     /locus_tag="FNV62_RS46375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47050"
                     /product="LAETG motif-containing sortase-dependent surface
                     protein"
                     /protein_id="WP_143610308.1"
                     /transl_table=11
                     /translation="MISKRAVTAAAVAATAAVLLASGDAYACSIGDFTAKATCDTSTGE
                     ARAAITITDKDPSGTPADITVRIRMAVGTDGETVGTGHIDHPTAAGASTTILVPWLQGY
                     QWNVSVTAGNLVDERLTDLPISPDTPCVPATSPTSGTPTVGPAPSVSPTAGVTPTSSAA
                     APLASTSSAPSTSASSPVAGTRLAETGGGSDTGLIAGSAAAAIAAGTGLLFVMRRRTTA
                     GRH"
     gene            complement(8240..9095)
                     /locus_tag="FNV62_RS46380"
                     /old_locus_tag="FNV62_47055"
                     /pseudo=""
     CDS             complement(8240..9095)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713379.1"
                     /locus_tag="FNV62_RS46380"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47055"
                     /product="SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTAKPSEAWDTAVGVARVRARETRRENPLFLDPFAEAFAAAGSL
                     PVDGKPPRAPVDDAARRRWGPAALGRGRVLDRGPHPLPRRAAARRGRRGLPPGGPARRR
                     HEQPGLPARLAVGDPPVRDRNGGAAGLQGVGAPGRAGRSALRADHRTGRPARGLDRCPG
                     RCRARSGAPHGVDRRGPADPPAAGCGRTPARAGGGAVRDRQPDGPDAGSTRCRRALRAG
                     HRHRGVDAGLRDAARPGHLAGRSRVGHPRVHRA"
     gene            9339..>9389
                     /locus_tag="FNV62_RS57275"
                     /pseudo=""
     CDS             9339..>9389
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024980.3"
                     /locus_tag="FNV62_RS57275"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTFSAIAQMLHRHGFSH"
     gene            9514..>9762
                     /locus_tag="FNV62_RS56300"
                     /pseudo=""
     CDS             9514..>9762
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676514.1"
                     /locus_tag="FNV62_RS56300"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTPPTTRTWARRGRTPVIRVRGRAQRRFSIAALACYKQGERSRLI
                     YRPKRHIDHKRGGRRSFTWTDYRDPLIAAHQQLGTPMV"
     gene            10001..12649
                     /gene="lanKC"
                     /locus_tag="FNV62_RS46390"
                     /old_locus_tag="FNV62_47065"
     CDS             10001..12649
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040503.1"
                     /locus_tag="FNV62_RS46390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47065"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_144316223.1"
                     /sec_met_domain="micKC (E-value: 1.9e-225, bitscore: 750.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.8e-09, bitscore: 36.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.9e-05, bitscore:
                     21.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADAHFYETPDRLATGVAGAAQGTVPVFETARRPIP
                     EGWATARVGDWLTLTPLGADGAPAAAPAQGWKIHASATRANADRIAAIVWDYCFPRRIP
                     FKFVPGPHLLHLRNTKYAGRDTSGKFVTVYPADEEQLHTVLRELGSLLEGFEGPYILTD
                     LRWHDGPLYVRYGAFARMYVVDERGSLVPAVRDGSGTLVPDRRAPSFQVPEWVALPAFL
                     EPHLAARNTTTVGELPYRIEKALHFSNGGGVYAGTDTRNGRKVVLKEGRPHAGLASDGA
                     DAIARLEREKRALEAVAGSGVVPEVRDWFTLGDHRFLVMDFVAGRPLNSFFAERHPLLS
                     PDPDPQAVAAYTAWAVSIHRAVECAVEKVHARGIVFNDLHVFNIMVAPEEESVFLIDFE
                     AAAPAEENGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTTLLVVDRGKAAHL
                     AEVIAQQFPDVPREFLDEAVAEITRDVCGTGAPVGGTGAPERVPSAPASRVEPGDWPHS
                     RDSMIKAILASATPERDDRLYPGDVAQFSDGGGLGLAHGAAGVLYALAAVGAERHDEGE
                     RWLLDHTAPAPTGTPLGLYDGLAGVAHTLDLLGHRQRALDLVDGILRERWQHLSSDLQG
                     GLAGLGLVLGRLAATTGESELHERAAEAADLLVRRLAEPAPAAPRRRAGLMRGASGPAL
                     FLLRRYEETGERALLEAAGVALRRDLECCAEREGGAVEVDEGWRTMPYLGDGSVGVGLM
                     LDDYAAHVPDAGAEFARARAGILTAATSRFYAQPGLFQGRAGMILHLARTTAPGATRAR
                     LDEQIAGLGWSAMPYQGQLAFPGHQMMRLSMDLATGTAGALLALAAAFGSGDEGVAAHL
                     PFLPPPHRRPL"
     gene            12731..12847
                     /locus_tag="FNV62_RS46395"
                     /old_locus_tag="FNV62_47070"
     CDS             12731..12847
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="FNV62_RS46395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47070"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_054233519.1"
                     /transl_table=11
                     /translation="MALLDLQTMESDEHTGGGGNSTVSLLSCISAASVLLCL"
     CDS_motif       12731..12790
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMESDEHTGGGGN"
                     /locus_tag="FNV62_RS46395_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12791..12847
                     /prepeptide="core"
                     /locus_tag="FNV62_RS46395_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="24.00"
                     /molecular_weight="1672.0"
                     /monoisotopic_mass="1671.0"
                     /core_sequence="STVSLLSCISAASVLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMESDEHTGGGGN"
                     /leader_location="[12730:12790](+)"
                     /alternative_weights="1690.1"
                     /alternative_weights="1708.1"
                     /alternative_weights="1726.1"
                     /alternative_weights="1744.1"
     gene            13014..14726
                     /locus_tag="FNV62_RS46400"
                     /old_locus_tag="FNV62_47075"
     CDS             13014..14726
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128988.1"
                     /locus_tag="FNV62_RS46400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47075"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_143629572.1"
                     /transl_table=11
                     /translation="MSMDPTTGGLLTAASRHSGPRWAALCLVSVATTGAGLLLPAALGR
                     ALDLLLAHAPATRWVLICATLVLLLTGLDACETVLAGTLDARTTAFLRRRVTGHVLALG
                     PRATLRFGPGDLVARLVGNAAQAGTAPGARAALLAALAGPVGGVVALGVIDPWLAAAFL
                     TGAPLLTLLLRSLARDTSTCVADYQRVQGRIASALAEAVGGTRTIRAAGTADRDAERIL
                     RPLPELSRAGRRMWRVQGRAAARAVAVAPLLHLAVVAVAGMLLSRHRLSAGDVLAASRY
                     AVLATGVGVLVGQLSGLVRARTAARRLGEVLAEPAPTHGDRSLPPDGPGHLELRGVSAR
                     RGARTVLDGVDLVVPGGTTLALVGRSGAGKSLLAALAGRLTDPDAGEVLLDGVALPALS
                     RAELRAAVAYAFDRPALLGTTVEDTIALGLRCPSPARVREAARTACADAFVRRLPDGYA
                     TAVADAPHSGGEAQRLGLARAFAQRGRLLVLDDALSSLDTVTEHQVSEAVLGRAATGTR
                     LVVAHRAATAARADTVAWLDAGRVRAVGTHAQLWRRLPGYRAVFGAAGEEAGA"
     gene            15143..>16189
                     /locus_tag="FNV62_RS56305"
                     /pseudo=""
     CDS             15143..>16189
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.3"
                     /locus_tag="FNV62_RS56305"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVSRSFVFTSVGALAGLCSLAPLLLLPVVPPLVAGVALFAATLRP
                     LARRQEAYLAADEALAENLGAVCPGLRDVTAAGAEDRIAADAGALADAEQRAARALARW
                     GVARVVCLAVGGHLPLVLLLAGTPWLLDHGVTPGAVLGALAYVSQSLLPALTGLIHGLG
                     TSGSRLTVVLRRLTPPPPAVSRPAVTELTPHTPPPCPSTPAVPPALALTSLTFSYGPAC
                     APVVDDLTLALPSGAHLAVVGPSGVGKSTLAGLVAGLLKPVRGDIRICGCRVPGREAAA
                     GRVLIPQEAYVFSGGLRENLAHLRPDPVPEAELLAAAEAVGLTPLLNALGGPGASVDPA
                     TLSAGERQL"
     gene            complement(16472..17080)
                     /locus_tag="FNV62_RS46410"
                     /old_locus_tag="FNV62_47085"
     CDS             complement(16472..17080)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354522.1"
                     /locus_tag="FNV62_RS46410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47085"
                     /product="response regulator transcription factor"
                     /protein_id="WP_143604150.1"
                     /transl_table=11
                     /translation="MIQVLLVHDGCLVRSVLAQWLSREPDLRVDDVPWRRASRHVRALR
                     PDVCAADLDCSDTAGIPPLGELGLRGGGQVLSRLLVLATANRPGLLRRALEAGALGYVD
                     KTGTPEQLLRGIRKVAKGERFVSESLGFGFLKAAEMPLTRRELSVLTLAAEGASVAEIA
                     GSLHLSHGTVRNYMAAITRKTGARNRIDAIRISQSQGWL"
     misc_feature    complement(16631..16633)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16844..16846)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(16880..16882)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17690..17705)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    complement(17692..17705)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.01"
                     /tool="antismash"
     misc_feature    complement(17759..17776)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            17791..19434
                     /locus_tag="FNV62_RS46415"
                     /old_locus_tag="FNV62_47090"
     CDS             17791..19434
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019059462.1"
                     /locus_tag="FNV62_RS46415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47090"
                     /product="APC family permease"
                     /protein_id="WP_143604151.1"
                     /transl_table=11
                     /translation="MASVDQLAPPSTSQNRSSLRRNVGLIGLLWASAGSIIGSGWLYGA
                     KNAVVAAGPAALISWGIGAVAIVLLAFVHAELGGMFPVAGGTARYPHYAFGGLAGMSFG
                     WFAWLQAATVAPIEVEAMIGYAGHWHFAKSFLNDNGTLTTSGFIVAVILMGVFVAVNFL
                     GVSVLARTNSAATWLKIFVPLLAIFTLAATHFHSSNFTSHGFAPFGSKGVLAAISTSGI
                     VFALLGFEQAIQLAGESRNPKRDIPRAVLGSVAIGTLIYVLLQVVFIGALPGSSFAQGW
                     DKLDFVGISGPFAGLATLVGLGWLTVVLYFDAIVSPGGTGLIYTTSTSRISYGLSKNGY
                     APRVFERTDARGVPVYGLIMSFVTGVVCFLPFPSWQQLVGFITSASVLMYAGAPLAFGA
                     MRRRLPNRERSYRLPLGGVLSPLAFIVASLIIYWSGWQTLEKLGEAIVLGYLLLGGYAL
                     YASKKGLPNAPRISWKSAQWLPVYLLGIGVISWQGTFGGGQGNLPMWTDIAVVAVFSLA
                     IYHWAIRVALPTDAIEQNIEDIEVVDAGGH"
     gene            complement(19567..20669)
                     /locus_tag="FNV62_RS46420"
                     /old_locus_tag="FNV62_47095"
                     /pseudo=""
     CDS             complement(19567..20669)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057186.1"
                     /locus_tag="FNV62_RS46420"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47095"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTTPMEADGAGRARYTYRLRVSSSARTALEAEWALARERTPWLRE
                     GSSVPQQQLIRDFGKSRAKAHKDIRERLPQRQRAGMPGWKKKHEALPTLNCTRRGLRPQ
                     DDRLHLAGGIVLTVVWSRSPPGEPSSVRVYRDSVGHWYASFVVPPRCSRCRRPAGCSAW
                     TGA"
     gene            20668..20874
                     /locus_tag="FNV62_RS57715"
                     /old_locus_tag="FNV62_47100"
     CDS             20668..20874
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015807.3"
                     /locus_tag="FNV62_RS57715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47100"
                     /product="Arc family DNA-binding protein"
                     /protein_id="WP_143604152.1"
                     /transl_table=11
                     /translation="MIRFSLRIPADLHEQVTARAAADRRSLNSEILHLLEVALTAPRPD
                     AGSPSGDPASPAPLRGKPDSSPA"
     gene            complement(21072..21767)
                     /locus_tag="FNV62_RS46430"
                     /old_locus_tag="FNV62_47105"
     CDS             complement(21072..21767)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360465.1"
                     /locus_tag="FNV62_RS46430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_47105"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_097287810.1"
                     /transl_table=11
                     /translation="MSHHHAPSASETLAKPLRRDAQRNRDAIVAAARTAFSEQGLGASL
                     EGVAREAGVAIGTLYRHFPTRLDLVETLFNAKYTELLTTAEEAAAMDDAWEGFCRYLEK
                     LCQLQACDRAFNDLVSARLPLHVAGRKMYERTKELGIQIMRNAQEQGVLRGDVTAQDIA
                     FVIWSQAGIIQATRTIAPQAWRRHLHLMLDAFRTEGAHELPEPPLTSQQVDQTLVTLEC
                     TEEDCREQS"
     misc_feature    21847..21862
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            22030..22413
                     /locus_tag="FNV62_RS46435"
                     /old_locus_tag="FNV62_47110"
     CDS             22030..22413
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS46435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_47110"
                     /product="hypothetical protein"
                     /protein_id="WP_143629574.1"
                     /transl_table=11
                     /translation="MNSMTKRVSIALASTALAGGALLGAGGSASAATTPVPVQHTQYVS
                     ATSATSTEQVGHHKDDGRRDDHRGQDTVRYVRAADHEGEAASWRGVSAARWYEDQVDAA
                     TSWHGVSTARWHEDQVVWSLNHS"
     misc_feature    22530..22541
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 gagctgcccg cgcagcacct caccgagggc agcgcgaacg ggctggccct ggtcatcggc
       61 agcgactggc cctccggcgc aacgtactcg ggcggctcgt cggccgcccc cgccgacacc
      121 cacgccgccg tctccaacgc ccatgcccag accgctgacg agtccaagtg cgccaaggtc
      181 agcccgtaca agaccgttca gctcaacggg gtggcgatga ccccggccca ggcatacgcc
      241 gcggcgagcg gcaagcagga ctccgcgccg tgatcaacgg ggccgcctcc tcgcctgaag
      301 atcacggacc ctcgaggctc ttcgcccctg gacgagcacc agaccgatgt gatgttgcag
      361 gtggcgtacg cccccaaggg cgtcgccgag acggcagccg acaagctggg gttcgtcaag
      421 cggcagatcc ccggggttct gaaggttcaa gtcgttcatc gagaaccgca gccgtgcggg
      481 acggacatca cgtcccgcac ggctttgtgc tgccacacgt ggggccaacc gctcttggtc
      541 agttcaccgg gtagccagcc cggagcgatg ccatgcccgt cggccagtga cagcggacgg
      601 aagccgacat ccgcagggtg ctgtgccgcc tctggggtga ggaggaggcg aaccccgcgc
      661 cgccctatga agggcatccc catcagcggc agcgaggttg cacaccgcac atgcccaggc
      721 tggtccagta cccatcgcaa ggcgcacccc agccaggccg aggcggactg aacgccacgc
      781 cggcggcatc tccctcggcc caccaccgtc gccctgaagt gccgaattca gtcacgcggc
      841 ggcgcgacga acgtgatcag cgtcggcttc cccgctgcgg tgttatgaag ggtgtatgga
      901 ggtattttct gggcgtcctc ggagcccgga acgtcatccg ctcaccggac gctcgcggca
      961 acaccgtgct tccccgctgg acctgcgcag tgcggccggt caagtattcc ttctccaggt
     1021 tgtcatcgtg gtcctgctgg tcgtggccgc ggtggcggcc gtggtgctcc agacggcgcg
     1081 cgacgcggtg cagcgggggc gtcgtgagtc ggtcgtcgcg gcccagtcgt tcgcgagtgc
     1141 tcctggcacg gccgaggcgc tgcggagccg tgatccgacg gcggtgctcc agccgcgggc
     1201 cgaggaggtg cggaaacgca cggatgtgga cttcgtcgtc gccatgaaca cgcaggggat
     1261 tcgttacacg tatccctatc cgagcgagat cgggaagaag tttgtcggca cgatcgcacc
     1321 ggcgctgaag ggccgtaccg tcgtcgagca ggccggcgga ccgcctctgc ccgcgggcaa
     1381 aggaaccgcc gtgcaggcgg tggtcccggt gaccgactcg cgcggaaagg tggtcggcct
     1441 ggtctccgcc ggaatcacgg tcaaggacgt cgcggcactg tggctgccgc agctgccgat
     1501 catcctgggc agcggcgcgg ccgcgctggc gctgtccatg acaggaacga cgttggtggc
     1561 ccggcggctg cgtcggcaga cacacggcct ggccccggcg gagctggcgc agctgtacga
     1621 gcaccacgac gcggtcctgc acgcggtgcg ggaaggagtg ctgatcactg gcaccgacgg
     1681 acggctgctg ttggccaatg acgaggcgag gcgtctgctc gacctgccgg cggacgtgca
     1741 ggggcgcccg gtgcgggagc tgggactgcc ggagccgatc acgcgtctgc tgtcgtcgcc
     1801 ggaggcggtc accgatgagg tgcatcgcgc aggggaccga ttgctggcgg tgaacaagcg
     1861 gccaacgtac cggcaggccg accgaggagg cagcgtggtg accctgcggg acaccacgga
     1921 gctggcggtg gtctcggggc gggccgaggt cgcgcgggag cggctgaagc tgctgtacga
     1981 ggccggggtg gggatcggca cgacgctgga cgtgggacgt acggcgcagg agctggccga
     2041 cgttgcggcg ccggagttcg ctgacctggt gacggtggac ctgctcgacg cggtactgcg
     2101 ggggtgggag ccgacggcgg agggctggcg gcatctgcgc cgggcggcga tcggcggtga
     2161 acagccgatg atcccagtgt atccgctggg cgaagtgatc acgttctcgc gccgaacgcc
     2221 gcaaatgcgg acgctgcagg agcgacgagt cctgttggag gcggacctgc ggcaggcaca
     2281 cggctggcgg gagcaggatc cggagcgcgc ccggaaggcc ctggagtgcg ggttgcgctc
     2341 gctggtgacc gtaccgctcc aggcgaggaa cgtgccgttg ggcgtggtga acttctatcg
     2401 gacagtggat tccccggcgt tccagccgga ggatctctcc ttcgcggagg aactggccgc
     2461 gcgggcggcc ctggccatcg acaatgcccg gaggttcacc cgggagcacg cgatggcggt
     2521 gacgctgcag cgcagtctgt tgccgcgggc acagccagat caggacgcac tggaggtggc
     2581 ctggcggtat ctgcccgcgg aggcgggtgt gggcggggac tggttcgacg tcatcccgct
     2641 tccgggcgct cgggtggccg tggtcatggg tgacgtcgtc ggtcacgggc tgcacgcggc
     2701 ggcgacgatg ggccggctgc gtaccgcggt gcacaacttc tccaccctgg acctccccgt
     2761 tgacgaggtg ctcgggaagc tggacgacct cgtcctcagc atggacaacg aggagaacgc
     2821 gggcgatgcc gcggagggcc acgaggggga gggggtgacc ggagcaacct gtctctacgc
     2881 ggtctacgac cccgtgtcgg aggcctgcac gatggcccgt gcgggacacc cggaaccggc
     2941 ggtggtgcgt ccggacggga cggtcacctg tcctggcgtt cccgcttcga cgccgctcgg
     3001 cctgggcggc tacccgttcg agaccgccga gttctccttg ccacagggtt cacaactggt
     3061 gctgtacacc gacggcctgg tggaggaccg cacccacgac atcgacgtcg ggatggagag
     3121 actgcgccag gcactggacg gttccgagcg ccgcactccg gaggagacgt gtcaggcggt
     3181 gatcgacgcg ctgaagccgt cacactcctc cgacgacatc gcgctgctgg tggcgcgtac
     3241 ccggatattc ccgccctcgc gcgtggccga gtgggacgtg ccgtcggacc cggcggtggt
     3301 tccctcggtg cgggcgcggt gcagggagac gttgcgggag tggggactgg aggaggccgg
     3361 attcgccacg gaactgatcc tcagcgagct gatcacgaac gcgatccggt acggcttgcc
     3421 gccggtcagt gcgcggctgc tgcacggacg ctgtctgatc tgcgaggtgt cggacggcag
     3481 cggcacctcg ccgcggctac ggcgggcggc gaccacggac gaaggcgggc gggggctgtt
     3541 tctggtggcg cagttcgccc agcgatgggg aacgcggtac acgacccgcg gcaaggtcat
     3601 ctgggcggaa cagtttctcc acgacggcac atccgccacc ccgagccgga caccggtcga
     3661 ctttcttctc gaccagttcg atgatctcga cgcgtgagcc cgcatggccc acgagcgtcg
     3721 cgtcccctct gcgcacgcgc cggagaccct gcacccttga gcacgacgac gcctgagggc
     3781 gcgagtttga cctgggcgtt caggaaccgc ctccagttat gtgcttgtga cgtgggacca
     3841 gcggcaacca cctgttcgta cctcggccag aaccgccaca acgcgttccc cagtcggctg
     3901 aaggagttgc gggccaagca cgtcagtgag cacgggatgc ccttcggctc gtaggtcgcc
     3961 ggatgggccg atgggccgtt gctcgtcctg tccgtcctcc cttccggggc ccaggacact
     4021 cacaactcac cccggaacga ggtcacatca cggcatcggt ctgaagcggg cgcgcagtga
     4081 tgcggagtgt ccggtccctt ccggacccgg acccggaccc ggaaccaacc cgcccgggcg
     4141 tcgccggacc cttccccgtc caaccgggaa ccttcgcggc gctccggacg ttgtagcgag
     4201 tggttgtagt tgaagtttgc gaacgtggaa gcgcccgtgg agttctgaca gcgggtgctt
     4261 cgccgttctc gggggttttc ttcgacggct ggcggctgac agcccgggat cgtgcgagcg
     4321 cgcgttctcc gcacctctcg ccacctcgaa ggagacgtga cgtggctcaa ggaaccgtga
     4381 agttgttcaa tccggacaaa ggtttcggct tcatcgcccc cgatgagggc ggcgcctaca
     4441 ccttcggcca ccactcagtg atcgacacgg ggggtttctg ctccctggag gagaaccagc
     4501 gggcgcagtt caccgccagc cggggcccca agggcatgca tgccgaccgg gtccgcgcgc
     4561 tctgagacac ctcattctga ggcagacccc gcgccgcgga cctgcctcgt gctgcttccg
     4621 aacggctgcc gcttgcggtg ccccgccgtc gtgtcggagg cagcgcccgt gcacgccgaa
     4681 aggaacactg tgaccactga catcaccatc cggggcaccg gtccggcgga ccacaccgac
     4741 atggctgaac ccccgcccgg cggccggggc agcgactacg ccgcactgtc ccgcgaggtg
     4801 aaacagagcg ggttgctgaa gcggaggccg ggctactact gcgtcaaggt cggggcgaac
     4861 ctgttcctgc tggccgcggg ctgggccgcg ttcgccctga tcggacagtc gtggtggcag
     4921 ctgctcaccg cagccttcct cgcggtgatg ttcacccaga ccgggttcat cgggcacgac
     4981 gccggacacc accagatcgc cgcctccaag cgcgtcaaca acgtgctcgg ccgtgtgcac
     5041 gccgacttgc tgatcggcct cagttacggc tggtggatca acaagcacaa ccggcaccac
     5101 tcccacccca accacgtcga ccgcgacccc gacatcgccg acggcgcgat cgccttcacc
     5161 caggaccacg cccgggtccg cagcggagcg tacgcatggc tggcccgtca ccaggcctgg
     5221 ctgttcttcc cgatgctgct ccttgaagga ctcgcccttc acatcgccgg agtacgggcg
     5281 ctgctggacc gcaccggtac cgcaacctcg cgggcggcca aactggccga ggcgggactg
     5341 ctgacggcgc atctcggcgg ctatctcgcc gccgtgttcc tggtcctgtc tcccgtccag
     5401 gccgtgtgct tcctcgtcgt gcaccaaggg ctgttcgggt tgtacatggg gtgctcgttc
     5461 gcccccaacc acaagggcat gcccgtcttc gccaaggacg acaagatcga cttcctgcgt
     5521 cggcaggtac tgacctcacg caacattcgg ggccaccggt tcaccgattt cgcacttggc
     5581 ggactgaact accagatcga acaccacctg ttcccctcca tgccgcggcc cagcctgcgc
     5641 catgcccagg aactcgtgcg caccttctgc gcccggcacg gtatcgccta ctacgagacc
     5701 ggactcctca actcctacgc ccaagtgctg cggcacctcc atgcggtcgg cggccccctg
     5761 cgccccgaaa tggagtactg agcagctgcc gccggtgccg gccgacggac atacgctgag
     5821 cgtcgtcttg acggagttcg gcgggcacac cactccggtg gccacgcgcc ggcacaccgt
     5881 gtggcaccga ctccatccgg ctcgacctgg tcctgctgca caaccccgag cgagcccacc
     5941 ccggcgaccg ttccgccctg ctctctgcca tccgggacgc gttcgcgatt ctggaggagg
     6001 aggtggcggc cgggcgcgtg gctgggtacg gggtcgccac gtgggcgggc ctggaggagg
     6061 cgttcacggt gggggagttg ctcgccctgg ccgccgaagc cgcgggcgga cagcaccatc
     6121 atctggtcgc ggtccagatg ccggtcagcc tggtgatgat gacgccgatc gcgcgggccc
     6181 ttcacggccg gggtccgctc ccggccgccg ccgacgtggg actgcgggtg atggcgtcgg
     6241 cccccgctgc accgcggtga gctccccggt atggtcggcc aggagttcgc cgacctcatc
     6301 cggccgggcc tgacccccgc acaagcgtgc atcctcgccg tcgcgtcatg cccaggggtg
     6361 acggacgtcc ttctggccgc ctccggtgcg ccacactgga gggaggcggc cgacgccgtc
     6421 gcccaaccct ccctgaccgc cgccaagttg cgggagtcgg cacggcaccc gtcgagtttc
     6481 acctaccggt cctaactaag ccgctgtacg tggcggtggg tgatcagaca gacggcgagt
     6541 ccgaggaatg cttcgtggat gtcgtcgcgt cgttcccagc gagtgcgaag gcgtcggaag
     6601 ccgtggagcc atacgatcgt ccgctcgacg acgtagcgga agatgcccag gccggtgccg
     6661 tgaggctcgc ctcgcttcgc gatcacgggg cggatcccgg gggctcggag caggcggcgg
     6721 tatttgtcgt ggtcgtagcc gcggtcggcc ggcagcgcat cggggcgtcg gcgaggtctg
     6781 ccgacccggc ccgcgatggc cgggatcttg tcgagcaggg gcagaagttc atcgggaacg
     6841 atccaaggcc gcgactgacg tttccccgca accagaccaa cgaacagaca agccaacagc
     6901 cacatgatca acagcttttg ttggagccag ttggcgaaca gacgtgggaa atctggtgcc
     6961 tatgccctac aggccacaac gtggagcggg tgagatggcg acccgcctcg aacgggtggc
     7021 cgcagggact cccgaactca tcgacattga tcacgagccg ggcccccgag gtgactcccg
     7081 aatgccccta caaacgcctc ccgttctcgc gttcacagcc ggcccgcaga gctttgaaca
     7141 gttgctaccg cttggaccca tgcaagcggg tgggtcgctg ggcaggggcc gtacgtatcg
     7201 tcagatgcat acgacccctg tcctcggccc ggcccggcgc gggtccgtgg tcagtgccgt
     7261 ccggccgtcg tgcggcggcg cattacgaac agcaggcctg tgccggcggc gatcgccgcg
     7321 gcggccgatc cggcgatcag accggtgtcg ctgccgcctc cggtctcggc gagcctggtc
     7381 cccgcaacgg gcgaggaagc ggacgtcgaa ggggctgagg acgtcgaggc caacggcgcg
     7441 gcggccgacg aggtcggcgt gacgccggcg gtcggcgaca ccgagggggc cggcccgacc
     7501 gtcggggtgc cggacgtggg ggaagtggcc ggcacgcagg gggtgtccgg ggagatcggc
     7561 aggtccgtca ggcgctcgtc gacgaggttg cccgccgtca ccgagacgtt ccattggtag
     7621 ccctggagcc acggcaccag gatcgtcgtg ctcgcacctg ccgccgtggg gtggtcgatg
     7681 tgtccggtgc cgacggtttc gccgtcggta ccgaccgcca tccggatccg cacggtgatg
     7741 tccgcgggcg tgccggaggg gtccttgtcc gtgatcgtga tggcggcccg ggcctcgccg
     7801 gtgctggtgt cgcacgtcgc cttcgcggtg aagtcgccga tgctgcaggc ataggcgtca
     7861 ccagaggcca ggagcacggc agctgttgcg gccacggcgg cagcggtgac ggcacgcttg
     7921 gatatcacgg gtccctcccc agggaacgtt ccacgtgggg tgcccggatc ggggcccccg
     7981 ctggccgcgg gcgcacgccc gcggatggct tcgaggggcc caaaggccgg tcggagcggc
     8041 tcatcatgtc acctctcccc acggggaacc tgaacgggcc cctagttgag aggtcaccca
     8101 gctcaaggca acaagccgcc gagagggctg cccgtaacgc tgaaggtctc ccggcacatg
     8161 gcggccgaca cctacggtgg acttcaccac gaggcgtagg agaccgccat gagtcaggaa
     8221 ccgcggacgc gcgccgtgct cagcggcgtg ccgcggagat caggacgccg tgcctcggcg
     8281 gctgctcctc gggtgccgtg accgggcgtc cgtacgccgc cgcgcgttca cgcacggtgt
     8341 acgcgcgggt gtcccacccg agaccggcca gccaggtgac cgggtcgggc ggcatctcgg
     8401 agacccgcat cgacgccgcg gtgccggtgt cctgcgcgaa gcgctcgacg acaccgggtt
     8461 gacccagcgt caggcccatc cggctgccgg tcgcggacag ctcccccacc tgcccgagca
     8521 ggcgttcgac cgcatcctgc ggcaggtgga tcagcaggcc ctcggcgatc cacaccgtgg
     8581 ggagcgccgg atcgtgcccg gcagcgacca gggcaccggt ccagtcctcg cgcaggtcga
     8641 ccggtacggt gatccgctcg cagcgcggat cggccggctc ggcccggagc accgactcct
     8701 tgaagcccag cggctccgcc gtttcgatct cgaacaggcg ggtctccgac ggccagtcga
     8761 gccggtaggc ccggctgttc atgccggcgc cgagcagggc cacctggcgg cagcccgcgt
     8821 cggccccgtc gcgcagcagc tcgtcgagga agcgggtgcg gaccacgatc gagaacgcga
     8881 ccgcgcccca gcgccgccgg gccccagcgc cgccgggccg cgtcgtccac gggcgctcgc
     8941 ggcggcttcc cgtccaccgg caggctgccg gcggcggcaa atgcctccgc gaacgggtcc
     9001 aggaacaagg ggttctcgcg ccgggtctcc cgtgcccgca cccgggcgac cccgacggcc
     9061 gtgtcccagg cctcggacgg cttcgctgtc gtcatgactc gcccctcgtc aacgaggcgg
     9121 cttctcgccc ggctccgtag agccttgacg gccgagccct ggcggggagc atgccctggc
     9181 gtcgaaggga ccggtgtcca ggctcaagct gagagaggcg ctggctgcgg tggctggagc
     9241 aggatctggc cgaggggccg gtggcgcacg gctggccggg ccagacctgg acgctgtcgc
     9301 ggatcagcac cctgatcggg cgccgttccc acaaaggcat gaccttttcg gcgatcgcgc
     9361 agatgctgca tcgtcatggc ttcagccatc aggttccggc ccgtcgtgcg gtggagcgcg
     9421 acgaggacgc cgtgagcggc tgggtgaaga gacctggccg caggtggaag caccgtggcg
     9481 ggggtctgct tcgaggacga ggcgggcttc tcgatgacgc cgcccaccac gcggacctgg
     9541 gccaggcgag ggcgcacgcc cgtcatcagg gtgcgcggac gtgcccagcg ccggttctcg
     9601 atcgccgctc tggcctgtta caagcagggc gaacgctcac gtctgatcta ccggcccaag
     9661 cggcacatcg atcacaaacg gggcggcaga cgcagtttca cctggactga ttacagggat
     9721 ccactgatcg ccgcccacca gcagctcggc accccgatgg tgccgatcgt tcccggcgac
     9781 ccgggccgga tatcgggatc tgtcggcatg agcctggctc gacgccccac gagagcaacc
     9841 cgcggagcac atgtgtccag gaggcggcgc ggggccgcga tcgaaacgag ccgaacatgt
     9901 ctttacccgt gcgtttcgca cagtgagctc gtgacagtcg tgactgtcgg tgccccaggc
     9961 cggcttgcga gtctcttggg cgggccacgg aaggggaggc atggacaagc ggtacgaggt
    10021 gtacgcgttg gcggacgcgc acttctacga gacacccgac cggctggcga cgggcgtcgc
    10081 aggggcggct caggggactg ttcccgtgtt cgagacggca cgcaggccca tcccggaggg
    10141 ctgggcgacg gcccgtgtcg gcgactggct gacactcacg ccgctcggcg cggacggcgc
    10201 cccggcggcg gcgccggccc agggctggaa gatccacgcc tcggccaccc gggcgaacgc
    10261 cgatcggatc gcggcgattg tgtgggacta ctgcttccct cgccgcatcc cgttcaagtt
    10321 cgtgccgggc ccgcatctgc tgcatctgcg caacaccaag tacgcgggcc gcgacaccag
    10381 cggcaagttc gtcaccgtct acccggccga cgaggagcag ctgcacacgg tcctgcgcga
    10441 gctgggttcc ctgttggagg gcttcgaggg cccctacatc ctcaccgacc tgcgctggca
    10501 cgacgggccg ctgtacgtcc gctacggcgc gttcgcgcgc atgtacgtcg tcgacgagcg
    10561 gggttcgctc gtgccggcgg tgcgcgacgg ctcgggcacg ttggtgccgg accggcgggc
    10621 gccgtccttc caggtgccgg agtgggtggc gctgcccgcg ttcctcgagc cgcatctcgc
    10681 ggcgcgcaac accacgacgg tgggtgagct gccgtaccgc atcgagaagg cgctgcactt
    10741 ctccaacggc ggcggagtgt acgccggcac cgacacccgg aacgggcgca aggtggtgct
    10801 caaggagggg cggccgcacg cggggctggc ttccgacggg gcggacgcga tcgcccggct
    10861 cgagcgggag aagcgggctc tggaggcagt ggcggggagc ggggtggtgc ccgaggtgcg
    10921 ggactggttc accctgggcg accaccgctt cctggtcatg gacttcgtgg cggggcgccc
    10981 gctgaactcc ttcttcgccg aacggcaccc gctgctctct cccgaccccg acccgcaggc
    11041 cgtcgccgcg tacacggcat gggcggtgag catccaccgg gcggtggagt gcgcggtgga
    11101 gaaggtgcac gcgcgcggga tcgtcttcaa cgacctgcac gtcttcaaca tcatggtcgc
    11161 gcccgaagag gagtcggtgt tcctgatcga cttcgaggcg gccgccccgg ccgaggagaa
    11221 cggccgccaa gtcgtggcgc atcccgggtt cttcgcgcca ccggaccgcc ggggcgccga
    11281 cgtcgaccgg tacgcgctgg cgtgtctgcg gctcgccctg ttcctgcccg tcaccacgct
    11341 gctcgtggtg gaccggggca aggcggccca tctggccgag gtgatcgcgc agcagttccc
    11401 ggacgtgcca agggagttcc tggacgaggc ggtcgcggag atcacccgcg atgtctgcgg
    11461 caccggggcc cctgtcggcg ggaccggcgc accggagcgg gtgccgtcgg cccccgcttc
    11521 ccgggtggag ccgggcgact ggccgcacag ccgcgactcg atgatcaagg cgatcctcgc
    11581 ctcggcgacc ccggagcgcg acgaccggct ctaccccggc gacgtcgccc agttctccga
    11641 cggcggcggc ctcggcctcg cgcacggcgc ggccggcgtc ctgtacgccc tggcggcggt
    11701 cggcgccgaa cgccacgacg agggcgaacg ctggctcctg gaccacactg ccccggcccc
    11761 gacgggcacc ccgctcggtc tgtacgacgg tctcgcgggc gtcgcccaca ccctcgacct
    11821 gctcggacac cggcagcggg ccctcgacct ggtcgacggc atcctgcgcg aacgctggca
    11881 gcatctgtcc tcggacctcc agggcggcct ggccggcctc ggcctggtgc tggggcgact
    11941 ggccgccacg accggcgagt cggaactgca cgagcgggcc gccgaggccg ccgacctcct
    12001 cgtacgtcgc ctcgccgaac cggcgccggc cgcgccccgg cgacgggccg ggctgatgcg
    12061 gggcgcgagc gggcccgcgc tgttcctcct ccggcggtac gaggagaccg gcgagcgtgc
    12121 gctgctggag gcggccggcg tggcgctgcg gcgggacctg gagtgctgtg ccgagcgtga
    12181 ggggggcgcg gtggaggtcg acgaggggtg gcggaccatg ccgtatctcg gggacgggag
    12241 cgtgggcgtg gggctcatgc tcgacgacta tgcggcgcac gtcccggatg ccggcgcgga
    12301 gttcgcgcgg gcccgtgccg gcatcctcac cgcggccacc tcccgtttct acgcgcagcc
    12361 cggcctcttc cagggacgtg ccgggatgat cctgcacctc gcccgcacca ccgcgccggg
    12421 ggcgacgcgg gctcggctcg acgagcagat cgccgggctg ggctggtcgg cgatgccgta
    12481 ccagggccaa ctcgccttcc ccgggcacca gatgatgcgc ctttccatgg acctcgccac
    12541 cggaacggcg ggcgcgctgc tcgccctcgc cgcagccttc ggctcgggcg acgagggcgt
    12601 tgccgcgcac ctgccgttcc ttccgccgcc gcatcggcgg cccctatgac atggctctgc
    12661 catccggcgg agtcgtgacg caaccctgtc cccacgggac gaacaaccga caccgacgaa
    12721 aggacacacc atggccctgc tcgacctgca gacgatggaa tccgacgagc acaccggcgg
    12781 cggcggcaac agcaccgtca gcctcctgtc gtgcatcagc gcggccagcg ttctgctctg
    12841 tctctgacga agcggtgccg aacgctctga cgaacggctc acgctgaaca ctccgggcgg
    12901 tcccgctccc gcgagggatg gggccgcccg gggtcgtccg cccgatcggg cggaaacgca
    12961 gaaacgcaga aacgcagaaa cgcagaggcg cggaagctcc gagggggtgc gcgatgtcga
    13021 tggacccgac gaccggtgga ctgctcaccg cggcgagccg gcacagcggg ccccgctggg
    13081 cggcgctctg cctggtgagc gtggcgacga caggcgcggg actgctgttg cccgccgccc
    13141 tcggccgggc cctggacctc ctgctcgccc acgccccggc gacccgctgg gtgctgatct
    13201 gcgcgactct cgtcctgctg ctgaccgggc tcgacgcgtg cgagaccgtg ctcgccggca
    13261 ccctcgacgc ccgcaccacc gccttcctgc gccgccgggt gaccggtcat gtcctggccc
    13321 tggggccgcg tgcgacgctc cgcttcggcc ccggtgacct cgtcgcgcga ctcgtgggaa
    13381 acgccgccca ggccggcacg gcgcccggcg cccgcgccgc gctgctggcc gcactcgccg
    13441 gcccggtggg gggcgtggtc gcgctcggtg tgatcgaccc gtggctcgcg gccgcgttcc
    13501 ttaccggcgc gccgctgctg acgctcctgc tgcgctccct ggcccgggac acctcgacgt
    13561 gcgtggccga ctaccagcgg gtgcaggggc gcatcgcgtc cgcgctcgcc gaggccgtcg
    13621 gcggcacccg caccatccgc gcagcgggca cggcggaccg ggacgcggaa cggatcctgc
    13681 gaccgctgcc cgaactctcc cgggcaggtc ggcggatgtg gcgggtacag gggcgggcgg
    13741 cggcgcgggc ggtggcggtg gcgcctctgc tgcacctcgc cgtcgtggcc gtggcgggca
    13801 tgctgctcag ccggcaccgg ctctccgccg gagacgtcct ggcggcctcc cgctacgcgg
    13861 tcctcgccac cggggtcggc gtgctggtcg ggcagctctc cggcctggtc cgcgcccgca
    13921 cggcggcccg ccgcctgggc gaggtcctgg ctgaacccgc ccctacgcac ggggaccgga
    13981 gcctgccgcc cgacggcccc ggccacctgg agctgcgcgg ggtgagcgcc cgacgcggcg
    14041 cacgcacggt gctcgacggc gtcgacctcg tcgtgcccgg cgggacgacg ctcgccctgg
    14101 tcggccgctc cggtgcgggc aagtcgctgc tggccgcgct cgcgggtcgg ctcaccgacc
    14161 cggacgccgg cgaggtgctg ctggacggcg tcgcgctgcc cgccctctcc cgcgccgaac
    14221 tgcgcgcggc ggtcgcgtac gccttcgacc gccccgccct tctgggcacg accgtcgagg
    14281 acacgatcgc cctggggctg cgctgccctt ctcccgcccg cgtccgggag gccgctcgta
    14341 cggcctgcgc cgacgcgttc gtccgccgcc tgcccgacgg ctatgcgacg gccgtcgccg
    14401 acgccccgca ctccggcggc gaggcccaac gcctgggcct cgcccgggcg ttcgcccagc
    14461 gcggtcgtct gctcgtcctc gacgacgcgc tctccagcct cgacacggtg accgagcacc
    14521 aggtctccga ggccgtcctg ggcagggccg cgaccggcac ccggctggtg gtggcccacc
    14581 gggccgcgac ggccgcccgt gccgacacgg tggcatggct ggacgcgggg cgggtccggg
    14641 cggtgggcac gcatgcacag ctgtggcggc ggctgcctgg ctaccgggcg gtgttcgggg
    14701 ccgcagggga ggaggcagga gcgtgaccca ccgggacgga ctccaccggc tgcacggaca
    14761 cctgggccac cgcgccctgc tcgccctgcg ctttttgtac gtcggccgac gggcgatggt
    14821 gcggctcgcc ggctggtcgg tgctggagac gggtcagacg ttcctcctcg gctacgccct
    14881 cgcgcgtgca ctggacgacg ggttcctggc cggacgggcc gccgtggggc tcggctggct
    14941 cgcggcagcc gggctcggcg tactcgtcgg cgcgtacggc accgggcggg tgtacggggc
    15001 ggtcgccgcg ctggtggagc cgctcaggga caggctcgtc accggcgtgg tgcggcgcgg
    15061 ggtgtgggag ggggaccgcg gggcgctgtc cggcctgacc cagcaggtcg agatcgcccg
    15121 ggacaccttc gcgggcctgg tcatggtctc gcgctcgttc gtgttcacgt ccgtcggcgc
    15181 gctggcgggc ctgtgctcgc tcgccccgct gctgctgctg cccgtcgtgc cgccgctcgt
    15241 cgccggagtg gctctgttcg cagcgaccct gcgtccgctg gcgcgacggc aggaggcgta
    15301 cctcgccgcc gacgaggccc tggcggagaa cctgggcgcc gtctgcccgg ggctacggga
    15361 tgtcacggcg gccggcgcgg aggaccggat cgccgcggac gccggcgccc tcgccgacgc
    15421 cgagcagcgg gcggcccgcg ccctggctcg ctggggcgtg gcccgcgtcg tctgtctcgc
    15481 agtcggcggc cacctgcctc tggtcctgct cctggccggc accccctggc tcctcgacca
    15541 cggagtcacc cccggcgccg tgctcggcgc gctcgcctac gtcagccagt cgctcctccc
    15601 cgccctcacc ggcctcatcc acggcttggg caccagcggc tcgcgcctga ccgtggtgct
    15661 gcgccggctg acgccgcccc cgcctgcggt ctcccgcccc gccgtcaccg agctcacccc
    15721 gcacaccccg cctccgtgcc cctccacccc ggcagtgccc ccggccctcg cgctcacgtc
    15781 cctcaccttc tcctacggcc ccgcctgcgc ccccgtcgtc gacgacctca ccctcgcgct
    15841 gcccagcggc gcccatctgg ccgtcgtagg gccgagcggt gtcgggaagt ccacgctggc
    15901 cgggctggtc gcgggactgc tgaagccggt acgcggagac atacggatct gcgggtgccg
    15961 ggtgccgggc cgcgaggccg ccgccgggcg cgtgctgatc ccgcaggagg cgtacgtgtt
    16021 cagcggcggc ctcagggaga acctcgccca tctgcggccg gatcccgtcc ccgaggcgga
    16081 gttgctcgcc gcggccgagg cggtggggct cacaccgctg ctcaacgccc tgggcgggcc
    16141 gggggcgagc gtggatccag cgacgctgtc ggccggggag cgccagctga tcgcgctcac
    16201 gcgggcgtac ctgtcgtccg cccccctcgt cctgctggac gaggcgacct gccatctgga
    16261 cccggtggcg gaggaacggg cggagcgggc gttcgcggcc cggccgggcg gcaccctggt
    16321 ggtcgtggcc caccgcatca gctcggcccg ccgcgccggc cgggtgctgg tgatggacgg
    16381 cccgcgcacg gccttcggga cgcatgagga ggtgctgcgc cgctcgcccc tctaccgcga
    16441 cctcgtgggt ggctgggaac ccgggcagct ctcacagcca gccctggctc tgggagatgc
    16501 ggatggcgtc gatgcggttg cgggcgccgg tcttgcgggt gatggccgcc atgtagttgc
    16561 gcacggtccc gtgggacagg tgcaggctcc cggcgatctc cgcgacggag gccccctcgg
    16621 cggcgagggt taacacgctc agctcccggc gggtcagcgg catctcggcg gccttgagga
    16681 atccgaaccc cagcgactcg ctgacgaaac gttccccctt agcgaccttc cggattccgc
    16741 gcagcagctg ctcgggcgtc cccgtcttgt cgacgtagcc cagcgcgccc gcctcaaggg
    16801 cccgtctcag caggccaggc ctgttcgcag tggcaagtac gagtaagcgg gacaggacct
    16861 ggccgccgcc ccgcagacct aactcgccca ggggcggaat gccggccgtg tccgagcagt
    16921 ccagatccgc cgcgcacacg tcgggccgca acgcgcgcac gtgacgggac gcccggcgcc
    16981 aggggacgtc gtccacccgc aggtcgggct cccgtgacag ccactgcgcg aggaccgatc
    17041 tgacgagaca tccgtcgtgc acgagaagta cctggatcac tgccgcccct tcaacctgcc
    17101 gtacgccagt cctgtgatgc tgagcgcgtg cccattgttg ggcccccgca acatttctga
    17161 gcgcgaagaa ccagccatca ggatgcgagg gggcgcacgc gcagcacccg cacgccgcgg
    17221 cgtgcttccg gcttcacctc gtaggtgtcc cgatggtcgt caacgaaccg gaagcggctc
    17281 ctcaccagtt cgtctctccg gcgagatact tggccgcctc gcggaggatg tcccgctcgg
    17341 tggcgagctt gcgctcactt gcctcgagct cggccccccc cgggcctcca accgccacac
    17401 ccgctcgtcc ggatcagcgg acggcaccgc cttccgaggc tgggcgccct tcgcaaccgc
    17461 ggcggtgatg ccacggcgtt cacggtcccg caacgcccac tcacgcaggg gaactgcggc
    17521 cggccgcgac cacggcttgg tcggcaccac ggcgacgact gcatcctgat catggtttcg
    17581 ccgccagggt cagatgcacg ccagcgggtc gccgcacggg atccaccacg tccagcggtg
    17641 gtcaccgagc cgcgcagacg atcatgagca gacgatcatg aatggacgtg atgaaaataa
    17701 ccattcagct gtatgggctg ttgcatggtg acattccgaa cctagcctgt ggcgactctt
    17761 aacgcaccac taacactgcg aggccgcccc atggcatctg tcgaccagct cgccccacca
    17821 agcacgagcc agaaccgcag ctccctccga cggaacgtcg gactgatcgg actgctctgg
    17881 gcgtccgccg gctcgatcat cgggtccggc tggctgtacg gcgcgaagaa cgccgtcgtc
    17941 gccgccggcc cggcggctct gatttcctgg ggcatcggcg cggtcgcgat cgtgctgctg
    18001 gcgtttgtcc atgccgagct gggtggaatg ttccccgtcg ccggcggtac cgcccgttac
    18061 ccgcactacg ccttcggcgg cctggcaggc atgtcctttg gctggttcgc ctggctgcag
    18121 gcggcaaccg tggcgccgat cgaggtcgag gccatgatcg gctacgccgg tcactggcac
    18181 ttcgccaaga gcttcctcaa tgacaacggc accctgacga cgagcggctt catcgtcgcg
    18241 gtgatcctca tgggcgtctt cgtcgccgtg aacttcctcg gtgtctcggt gctggcccgg
    18301 accaacagcg ctgccacctg gctgaagatc ttcgtgccgc tgctcgccat cttcaccctc
    18361 gctgcgaccc acttccacag cagcaacttc acctcgcacg gcttcgcgcc gttcggctcc
    18421 aagggcgtgc tcgccgcgat cagcaccagc ggcatcgtct tcgccctcct cggtttcgag
    18481 caggcgatcc agctggcggg cgagagccgc aaccccaagc gcgacatccc tcgcgcggtg
    18541 ctcggctcag tggccatcgg cacgctgatc tacgtcctgc tgcaggtcgt cttcatcggc
    18601 gcgctgcccg gcagcagctt cgcccagggc tgggacaagc tcgacttcgt cggtatcagt
    18661 ggccccttcg cgggtctggc cacccttgtc ggtctgggct ggctgaccgt ggtgctgtac
    18721 ttcgacgcca tcgtctcccc gggcggcacc ggtctgatct acaccacctc cacctcccgt
    18781 atctcctacg gtctgagcaa gaacggctac gcgccgcgcg tcttcgagcg cacggacgca
    18841 cgcggggtcc cggtgtacgg cctgatcatg tccttcgtca ccggcgtggt ctgcttcctg
    18901 ccgtttccga gctggcagca gctggtcggc ttcatcacct ccgccagcgt gctgatgtac
    18961 gcgggcgctc cactggcctt cggcgcgatg cgccggcgcc tgccgaaccg tgagcgcagc
    19021 taccggctgc cgctcggcgg tgtgctctcc ccactggcgt tcatcgttgc gagcctgatc
    19081 atctactgga gcggctggca gaccctggag aagctgggcg aagcgatcgt cctgggctac
    19141 ctcctgctcg gcggctacgc cctctacgcg tccaagaagg gcctgccgaa cgctccgcgg
    19201 atcagttgga agtccgccca gtggctgccg gtctacctgc tcggcatcgg tgtgatttcc
    19261 tggcagggca ccttcggtgg cggccagggc aacctgccga tgtggacgga catcgccgtc
    19321 gtggccgtgt tctccctggc gatctaccac tgggcgatcc gcgtggccct gccgaccgac
    19381 gcgatcgagc agaacatcga ggacatcgag gtcgtcgacg cgggcggcca ctgacccgtc
    19441 cgcactccct cataccgggg cggtcccgaa gcggccggtt ccaggacagg acagcacact
    19501 gtcccggctt tgactgctcc ccgcctgaag ggaggggatc ccttccttca ggcggggatt
    19561 cctggctcag gctgcctctg ggagcagtgc tcccggtggt cttacgccct cggcaccagc
    19621 cgggttcaga cctgcccgga cgagcatcat gcgggcggag ttcttgtctc tgggggagac
    19681 gactccgcat gcggtgcagg tgtaggtgcg ctcggacagc ggcagtgcgt gcttggttct
    19741 cgctccgcac gatgcgcagt ccatggtggt gtgtgcagga tgcacgagac ggatgtcccg
    19801 tccgtgcttg cggcccatct cgaccagggc cttcttcgtg gcgccgagcg cggcgtccgc
    19861 cgctttgcgg gccatcgagg acgtggcgag gagcttcggc ctgaagtcct cgacggcgat
    19921 ggcgtcgtgg tcggtcacga ccttcttcgc ccacttgcgg ccggtgtcgt gccgctgccg
    19981 ggcgatcttc acgtaggtct tcgcccgcca cttcttcgcc tcgcggtagc ccttcgaggc
    20041 ggcctgcccc ttcttcggcc ggcggctggc catcatccgg tcgtaacggg tcagcccagc
    20101 ctgcgcctta cggccgtgct gggcgtgcgg cagaccatgg gcgttggagg tggtggtcgc
    20161 ggtctccttc acgccccagt ccacgccgag cacccggccg gtctccggca gcggctgcac
    20221 ctcggtggga ccacgaacga tgcgtaccag tgcccgacgc tgtcccggta cacgcgcacc
    20281 gaggaaggtt cgcccggcgg gctgcgcgac cacaccaccg tcagcacgat cccacccgcc
    20341 aaatgcaggc ggtcgtcctg gggccgcaac ccgcgccggg tgcagttcag cgtcggcaag
    20401 gcctcgtgct tcttcttcca ccccggcata ccggcccgct gccgctgagg caggcgttcc
    20461 cggatgtcct tgtgcgcctt cgcgcgggac ttgccgaagt cccggatcag ctgctgctga
    20521 ggaactgagc tgccctcacg cagccacggc gtacgctccc gcgccagtgc ccactccgcc
    20581 tccagcgcgg tacgggcact cgacgacacg cgaagccggt aggtgtaccg ggcgcgcccg
    20641 gccccgtcgg cttccatggg cgtcgtcatg attcgcttct cactcaggat cccggcagac
    20701 ctacacgaac aggtgaccgc ccgcgccgct gcggaccggc ggtccctcaa ctccgaaatc
    20761 ctccacctcc tggaggtcgc cctcaccgct ccccggccgg acgccggatc gcccagcggc
    20821 gatccggctt cccctgcccc gctccgcggg aaaccggatt cctccccggc ctgaaggcca
    20881 gggcatcctc cgggaatccc ggtgacagcg cgggctgggg cagccggaag acggcggtcg
    20941 gacggcccgt ggtcctgccg cccggagtgc tgtccggggc cgtcccggcc ggtcgtccga
    21001 ggtactggtc cggtgtggcg ccggtccggt gtgatgcgca gctgttgtcc gcggacttgt
    21061 ctctcgtgtg gtcaggactg ctcgcggcag tcctcttcgg tgcactccag agtgacgagg
    21121 gtctggtcga cctgctggct ggtcagaggg ggttcgggca gttcgtgggc gccctcggtg
    21181 cggaaggcgt cgagcatcag gtggaggtgg cgacgccagg cttggggggc gatggtgcgt
    21241 gtggcctgga tgatcccggc ctgggaccag atcacgaagg cgatgtcctg cgcggtgacg
    21301 tcgccgcgca ggacgccctg ttcctgggcg ttgcgcatga tctggatgcc gagttccttg
    21361 gtgcgttcgt acatcttgcg gccggccacg tgaaggggca gccgtgccga gaccaggtcg
    21421 ttgaaggcgc ggtcgcaggc ctgcagctgg cagagtttct ccaggtagcg gcagaacccc
    21481 tcccaggcgt cgtccatggc agcggcttct tccgcggtgg tgagcagttc cgtgtacttc
    21541 gcgttgaaga gtgtttcgac caggtcgagc cgtgtgggga agtggcggta gagcgtgccg
    21601 atcgcgacgc cggcctcgcg ggcgacgccc tccagggacg ccccgaggcc ctgctcggag
    21661 aaggccgtgc gggcggcggc cacgatcgcg tccctgttgc gctgtgcgtc acggcgtagg
    21721 ggtttcgcca gtgtctcgct cgcggacggg gcgtggtggt ggctcatggc tcgagcgtaa
    21781 catgaggccc ccctcgaatt cgattgttgt catgtttccg atcgcaatct cactcctctg
    21841 acgtgctgtg atgagcctca ctgcaaacat gaggcacccc tcgggtacgg tggcagagcc
    21901 gaacgtgagg cacccctccg gatgaccttg cggcaagccg actgacccgg gatttccgga
    21961 tctcggttca catagaagcg gcggccgcca gctcggcgaa accgcggcag tctcgcaagg
    22021 ggaatgacca tgaacagcat gaccaagcgc gtctcgatcg cactcgcctc cacggcactg
    22081 gccggcggag cccttctcgg cgccggcggc tcggcgtcgg cagccacgac tccggtgccc
    22141 gtgcagcaca cgcagtacgt gtccgccacg tccgcgacca gcaccgagca agtcggccac
    22201 cacaaggacg acggccgccg cgacgaccac cgtgggcagg acactgtgcg ctacgtacgg
    22261 gctgcggacc acgagggcga agcggcctcg tggcgcggcg tcagcgccgc ccgctggtac
    22321 gaggaccagg tcgacgcagc gacctcgtgg cacggtgtca gcaccgcccg ctggcacgag
    22381 gaccaggtcg tgtggtccct gaaccacagc tgacgcggcc cgagccgccc cactccggaa
    22441 cgccggcgcc tgcccacaca gcaacacggc cgcacccccg gccgaccagg atcccggatc
    22501 gtgcgcccca cggcggttca cacttgcatg gagacgaacg ccgcacgcaa ggcgaaggca
    22561 ctctggccct cagcgccggc cacgccgacc acggccaggc ccgcaccgac acatgaacct
    22621 cgtcaaccgc ttcccttgcc gatcgcttc
//
