LOCUS       NZ_CP041610            21302 bp    DNA     linear   CON 14-NOV-2023
DEFINITION  Streptomyces sp. RLB3-17 chromosome, complete genome.
ACCESSION   NZ_CP041610
VERSION     NZ_CP041610.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RLB3-17
  ORGANISM  Streptomyces sp. RLB3-17
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/14/2023 04:19:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,027
            CDSs (total)                      :: 10,924
            Genes (coding)                    :: 10,421
            CDSs (with protein)               :: 10,421
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 503
            CDSs (without protein)            :: 503
            Pseudo Genes (ambiguous residues) :: 0 of 503
            Pseudo Genes (frameshifted)       :: 178 of 503
            Pseudo Genes (incomplete)         :: 409 of 503
            Pseudo Genes (internal stop)      :: 52 of 503
            Pseudo Genes (multiple problems)  :: 128 of 503
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4299843
            Orig. end                         :: 4321145
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041610.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041610.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21302
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="17"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21302
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21302
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11302](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11302
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(552..566)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     misc_feature    complement(1014..1029)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(1121..1136)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            complement(2410..3147)
                     /locus_tag="FNV62_RS19755"
                     /old_locus_tag="FNV62_20050"
     CDS             complement(2410..3147)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382060.1"
                     /locus_tag="FNV62_RS19755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20050"
                     /product="hypothetical protein"
                     /protein_id="WP_144315463.1"
                     /transl_table=11
                     /translation="MAEYEGVDALLAAITDEALPEGAGDDPEFLAEHRSAVADVALLRE
                     QLAVIGDALADRAQEAKPVPVRAPRKRTRRPEGAPRNRGRRPLALVLGTLVAATVAAMV
                     VGIGWILAHNGAGASDSSGAKAADSGTAGGGASLSAPGYLACARLVAEGTVAHVEPLPG
                     TTENRITLHVDRYYKPEKGRAEVVLVLDEEVAPRPREGERVLVAVQGDPATPTGWTTGD
                     KAIADERAWIVKALPASRTLTCP"
     gene            complement(3149..3670)
                     /locus_tag="FNV62_RS19760"
                     /old_locus_tag="FNV62_20055"
     CDS             complement(3149..3670)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116428.1"
                     /locus_tag="FNV62_RS19760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20055"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_054231760.1"
                     /transl_table=11
                     /translation="MLRRKARRVQGADDPLDAAQERRVRAVLALGGVPQADLPDGVQQV
                     RLRLLERAAKGDEAPRDVSAWAAVVASNLAMDWHRAKRRQERLGERLASLRQPADARDE
                     DSSVLSLAVARGLDELPDAQRQVLVLRFYADLSVRGIAEELGIPEGTVKSRLHSAVRAL
                     RARLHEDEVV"
     gene            3965..4981
                     /locus_tag="FNV62_RS19765"
                     /old_locus_tag="FNV62_20060"
     CDS             3965..4981
                     /EC_number="1.2.1.11"
                     /GO_function="GO:0004073 - aspartate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008652 - amino acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1219: N-acetyl-gamma-glutamyl-phosphate reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063171.1"
                     /locus_tag="FNV62_RS19765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20060"
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="WP_054231761.1"
                     /transl_table=11
                     /translation="MRVGIVGATGQVGTVMRRILVERKFPVEELRLFASARSAGTVLDG
                     VTVEDAATADYSGLDIVLFSAGGATSKALAEKVAAQGAVVIDNSSAWRKDPQVPLVVSE
                     VNPHAIADRPKGIIANPNCTTMAAMPVLKPLHEEAGLEALVVATYQAVSGSGLAGVAEL
                     HGQVLKVAADADKLTHDGGAVDFPEPGVYKRPIAFNVLPLAGSLVDDGLHETDEEQKLR
                     NESRKILEIPALKVSGTCVRVPVFSGHSLQVNARFARPLSVERATELLAGAPGVTLSEI
                     PNPLEAAGKDASYVGRIRADETAEHGLALFVSNDNLRKGAALNAVQIAELVAAELKG"
     gene            complement(5033..5563)
                     /locus_tag="FNV62_RS19770"
                     /old_locus_tag="FNV62_20065"
     CDS             complement(5033..5563)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986799.1"
                     /locus_tag="FNV62_RS19770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20065"
                     /product="DUF1203 domain-containing protein"
                     /protein_id="WP_225900303.1"
                     /transl_table=11
                     /translation="MTHTTDATTDMTTYATTYATTYTARPIDPAVLKDLRTADDADRPM
                     VPFADEEGGAPLRCCLRRSEPGERIALVSYAPLRRWAAGTGVDPGAYDEQGPVFIHADD
                     CPGPDLRGHPFPGAHRTVRRYSAEGHILGGRLVENPEAFDDAFDEAFADPEVALVHVRA
                     VEYGCFLYEVRRA"
     gene            5675..8254
                     /gene="pepN"
                     /locus_tag="FNV62_RS19775"
                     /old_locus_tag="FNV62_20070"
     CDS             5675..8254
                     /EC_number="3.4.11.2"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="pepN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014672746.1"
                     /locus_tag="FNV62_RS19775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20070"
                     /product="aminopeptidase N"
                     /protein_id="WP_144315464.1"
                     /transl_table=11
                     /translation="MPGTNLTREEAQQRAKLLTVDSYEIDLDLSGAQEGGTYRSVTTVR
                     FDVEESGSETFIDLVAPAVHEVTLNGDPLDPAEVFTDSRIALPGLLEGRNVLRVVADCA
                     YTNTGEGLHRFVDPVDQQAYLYTQFEVPDARRVFASFEQPDLKATFQFTVKAPTGWTVI
                     SNSPTPEPKDDTWVFEPTPRISTYITALIVGPYHSVHSVYEKDGQSVPLGIYCRPSLAE
                     FLDSDAIFEVTRQGFEWFQEKFDYAYPFKKYDQLFVPEFNAGAMENAGAVTIRDQYVFR
                     SKVTDAAYEVRAATILHELAHMWFGDLVTMEWWNDLWLNESFATYAEAACQAYAPQSRW
                     PHSWTTFANSMKTWAYRQDQLPSTHPIMAEINDLDDVLVNFDGITYAKGASVLKQLVAY
                     VGMDEFFKGVQAYFKRHAYGNTRLSDLLGALEETSGRDLKTWSEKWLQTAGINILRPEL
                     ETDANGVITSFAIRQEAPALPEGAKGEPTLRPHRIAIGLYNLDDDSGRLVRDQRVELDV
                     DGELTAVPELVGKRRPAVFLLNDDDLSYAKVRLDEDSLAFVTEHLGDFESSLPRALCWA
                     SAWDMTRDGELATRDYLSLVLSGIGKESDIGVVQSLQRQVKLAIELYADPTAREALLTR
                     WTDATLAHLRAAEPGSDHQLAWARAFSATARTPEQLDLLEGLLEDRESIEGLAVDTELR
                     WAFVQRLAAVGRYDEAEIGAEAERDKTAAGERHAETARASRPTEEAKAEAWAAVVESDK
                     LPNAVQEAVIGGFAQTDQRELLAPYTDKYFSVVKDIWDARSHEIAQQIVVGLYPSVQVS
                     EETLAKTDAWLAAAEPTPALRRLISESRSGIERALKAQAADAAAASA"
     gene            complement(8374..9648)
                     /locus_tag="FNV62_RS19780"
                     /old_locus_tag="FNV62_20075"
     CDS             complement(8374..9648)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116434.1"
                     /locus_tag="FNV62_RS19780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20075"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_144315465.1"
                     /transl_table=11
                     /translation="MRGTPYPTLGELLRRARATVAARPGALRLRAVGTSRAGRPLWLLS
                     AGHGPRHILTVAGAHANEPVGGVTSLSLAERFAREPALLQESGCTWNFLLCLDPDGASL
                     AGRWLTGLPGEGLPGEGRAAAEASPTLRGYYRRFYRPAFAAQPEFPPVTSDPRPVMPES
                     EALVRLIDELRPVVQFSLHGVEVGGSFLQLTRAVPGAAAAYRRIAADLGIPLEHRPFDG
                     MGWLAESPGVLVLPDSGPTEERDPSGFTSQATWLYAMRHGTVSAVVEAPFWSVAGVSDP
                     RPVAEPRREVAEASEILLGRAKQLEAVVGELGPRAPETPEEIAHFTAARELMDIGPGVV
                     DTWNSAELATTVGNAVSLGVAARRIPLRAAAMMRQALGGAPALDTLVEAWARELASTFD
                     ARWVPVTDQTELQIRTMLALARALV"
     gene            10001..11302
                     /locus_tag="FNV62_RS19785"
                     /old_locus_tag="FNV62_20080"
     CDS             10001..11302
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387620.1"
                     /locus_tag="FNV62_RS19785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20080"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_225900850.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 3.5e-22,
                     bitscore: 77.7, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.6e-40, bitscore: 138.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVDTLRRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWV
                     WTLVEAMDGTREPSAVVGEVLRAHPELPDLTSEDARQAMADLLDAGFVEDAAAPVPVSE
                     RERLRYSRGVPLLRWMDLGPRTSPWDAQLRLRRARVLLVGVGGTGGYAAQGLVASGVGR
                     LHCVDPDVVELSNLNRQPLFRESDLGRPKVTAALATLRALNSDVTVTGERREIRHPAEL
                     ARLIRTGAPEAPSEPKRAGTPQAPSEPTHAGTPEVPYSSRSSYDLLVLAADRPDDIRRW
                     ANRVCLAADLPWVDAGYRGPLVTAGVHVPGRGACWECLRAGEVARRELRLAPGQDDGVA
                     SPHLPWNPATAVTAGLSGGLLAHAALALLTGVPALDPGFRFGMNLMLPGDPVLQRFPRR
                     TDCPACGDRPDDGATGAGGATGPGGATGPAGERA"
     aSDomain        10019..10309
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FNV62_RS19785_Pantocin_Microcin_RRE.1
                     "
                     /evalue="8.90E-25"
                     /identifier="RREFam017.1"
                     /label="FNV62_RS19785"
                     /locus_tag="FNV62_RS19785"
                     /protein_end="103"
                     /protein_start="6"
                     /score="77.7"
                     /tool="antismash"
                     /translation="RRPRIKPEHRPYRTIDGNVRIGSVIHGIGAEIEDPQGWVWTLVEA
                     MDGTREPSAVVGEVLRAHPELPDLTSEDARQAMADLLDAGFVEDAAAPVPVS"
     gene            11299..12459
                     /locus_tag="FNV62_RS19790"
                     /old_locus_tag="FNV62_20085"
     CDS             11299..12459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116436.1"
                     /locus_tag="FNV62_RS19790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20085"
                     /product="hypothetical protein"
                     /protein_id="WP_144315466.1"
                     /transl_table=11
                     /translation="MNHVRLHALDSRPDGDEWIVGRLATGRFVALPEVGKQALDLLGQG
                     LSTTEVEERLRETTGDDIDVPDFVEALVDLGFVAEVDGREVASPPPPKPTLARIGPRHV
                     RWVLSPALPVLIALLITTTLLTRPPVPLGYRTLLWSPHGSAVIALGAGFGWTLLLLHEC
                     AHLMTARATGVPGRMRLGTRLQFLVMQTDISGIELAPRRHRLTAYLAGIATNLTVASLA
                     ALAAGATHGTPRRILAAVALLALLPLPFQLMVFMRTDLYFVLQDVTRCRDLYGDGVAYT
                     KYAARRALRRTTAPDPSLELPAHERRAVRAYSVVLVVGTTLCLVFLATVTLPADITLFA
                     RAVAHLGPGHSPAVRLDATAVVVALGGVHVVWARTWWRDRRGRRSS"
     gene            complement(12495..13271)
                     /locus_tag="FNV62_RS19795"
                     /old_locus_tag="FNV62_20090"
     CDS             complement(12495..13271)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063168.1"
                     /locus_tag="FNV62_RS19795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20090"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_097284748.1"
                     /transl_table=11
                     /translation="MLLTDKTAVIYGAGGSIGGAVARTFAREGAHVHLVGRTAATLDAV
                     AKDIEAEGGHAGTAVVDALDEAAVEAHIASLDAVDISFNLVTRGDVQGASLLDMSVDDF
                     VRPVVTGIRANVVTARAAARRMAERGSGVVLTLNSGSAHGSPMMGGTGPADAAIDTLVR
                     NLAMELGPRGVRAVGLWAAGVPETLTREKLAAVDSAMALDENALQGLLANLAGMRMTRR
                     NPTLPEIAATAAFLASDHAGGITGTFVNVTGGMFPG"
     gene            complement(13373..14674)
                     /locus_tag="FNV62_RS19800"
                     /old_locus_tag="FNV62_20095"
     CDS             complement(13373..14674)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019063167.1"
                     /locus_tag="FNV62_RS19800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20095"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_225900304.1"
                     /transl_table=11
                     /translation="MYCSAACRQRAYRERRAAPSDTAQGLIEEVGRQVRELVPAPPAVF
                     YSGVSELAASVGRLRRIARTARDTAGPGTADPVTEEPVLDEPVMGEPGAVDLVTTGPVT
                     EVALAESDFAALVESYRRELRVHCYRMSGSYDDAEDLVQETFLRAWRARDGFAGRASVR
                     TWLYRIATNACLDFQRRTARRPQRYEPLPGMNHGGAEPPARVTWLQPYPDDDLPSTEEQ
                     PDALAVSRETLELVFLAAIQHLPPRQRAVLVLRDVLGLAAAETAAVLDMTVASVNSALQ
                     RARPTLRDHLPRRRAEWTAEADVREREILARYMAAAERLDLTEVATLLSEDITLTMPPN
                     PFWFVGREALVEFLSVSLDPASPMFLGHWRHLPARANGQLAAGGYVRRPGTTVYRAQVL
                     DVLRVEGDRIVEITSFEPHLFPAFGLPLRLPADR"
     gene            complement(14809..15762)
                     /locus_tag="FNV62_RS19805"
                     /old_locus_tag="FNV62_20100"
     CDS             complement(14809..15762)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003543.1"
                     /locus_tag="FNV62_RS19805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20100"
                     /product="EamA family transporter"
                     /protein_id="WP_225900305.1"
                     /transl_table=11
                     /translation="MAANANRPALIALTALAPISWGSTYAVTTEFLPADRPLFTGVMRA
                     LPAGLLLLALARVLPRGAWWGKAALLGALNIGAFFPLLFLSAYRLPGGMAAVVGSVGPL
                     FVAGLAALLLGDRPTLRTLLTGIAAALGVSLVVLQAAGALDAVGVLAALAATASMSTGT
                     VLTKRWGRPDGVGPLALTAWQLTAGGLLIVPVALLVEGAPPALDGRAVGGYLYLALANT
                     AVAYWLWFRGIGRLSATQVTFLGPLSPLTAAVIGWAALGQSLTPVQVAGMVLAFGATVL
                     GQVGPRGGRPAPVGGFAGGGCGAGGAAITSRRPRVT"
     misc_feature    15796..15812
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            15889..16386
                     /locus_tag="FNV62_RS19810"
                     /old_locus_tag="FNV62_20105"
     CDS             15889..16386
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003542.1"
                     /locus_tag="FNV62_RS19810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20105"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_060900742.1"
                     /transl_table=11
                     /translation="MKTPQDPVDAIIEQWATVRPDLDTAAMEVFGRVFRLARTMGDRME
                     KAYAPYGISRGEFDVLATLRRSDAPYTLSPRQLSATLMLTTGGMTGRLDKLERAGLLRR
                     SPDPHDRRGLQVTLTDKGLRLIDEAVGAGLAVQTEALAHLDEERAGQLAALLRELLMGA
                     GA"
     gene            complement(16423..17283)
                     /locus_tag="FNV62_RS55710"
     CDS             complement(16423..17283)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS55710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225900306.1"
                     /transl_table=11
                     /translation="MYLHVKQKIVTLATALCLTVGAGTAAATGPAPKREPEGIFLGAAL
                     LAWLARAGASLDIDQYVYYDCDDQRGDGDPGQWRHPHPRITEDGSWISTRGLRRKPTLG
                     STLEPRWFRVVKRKLMGMTTTDYVISASLILLVIPQIRGVRQTLHHTLLPLAAVAAAAA
                     YYLKSFPTQGHDVGLDIAGVVAGAVLGVACGAATRLSRASDGIAFARAGALAALLWIVG
                     MASRAGFEYWATHGGSGSLARFSQDNLITGSAAWTAALLLMALAQVLGRLTVIRVRSSR
                     VAAAG"
     misc_feature    complement(17273..17286)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.47"
                     /tool="antismash"
     misc_feature    17277..17290
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.5"
                     /tool="antismash"
     misc_feature    17499..17514
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(17532..19037)
                     /locus_tag="FNV62_RS19820"
                     /old_locus_tag="FNV62_20115"
     CDS             complement(17532..19037)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136111.1"
                     /locus_tag="FNV62_RS19820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20115"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_225900307.1"
                     /transl_table=11
                     /translation="MNGKTNGKVNGTNGSRHVIVVGSGPTGLLLAGDLAAAGVPVTLVE
                     KRPHGISNLSRAFVLHARTLEQLDARGLADELESHGRTVDRIRLFGGLSVALDTLPSRF
                     NHLLVIPQYEVERALERRAVEAGVRFVYETEVTGLRQDAAGVTLEVRGADGAAGEMAAA
                     YVVGADGMRSAVREAVGLPFPGKSVIRSVVLADVLLAEEPESILTANAVGDAFAFMVPF
                     GDGYYRVIGWHRGRDVPDSAPLELDEVKEIVRLSLGHDYGMHDARWMSRFHSDERQAPA
                     YRVGRVFLAGDAAHVHTPAGGQGMNTGLQDAANLSWKLALVVNGHADTDLLDTYQAERH
                     PVGKAVLRSSGGIVRLAMAKYPWTLALRSVLTTVLNGVGPVRRKAAGQITGIGFAYRAP
                     RGSHALVGTRAPDVTLKGGRLYEALRGGRFVLVAPTAAVRAYGLDDLKGRKDRLAVESW
                     ASDRRTTLLVRPDGYVAWAAESPDAAAVERALAAALGEDPSSN"
     misc_feature    19081..19094
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            19151..19744
                     /locus_tag="FNV62_RS19825"
                     /old_locus_tag="FNV62_20120"
     CDS             19151..19744
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127872.1"
                     /locus_tag="FNV62_RS19825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20120"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_097284752.1"
                     /transl_table=11
                     /translation="MPDKELPAPAASPAARRSDTTRTAILTAARERFAADGYERATIRS
                     IAKDARIDPSMVMRYYGSKEGLFAAVLDVDLRLPDPVGLDPHEVGRALVGHFLDLWEEN
                     EVLTVLLRVGVTNPDGAARMQGIFRDQLMPVALRVCPDPEQAPARAALTASQVLGMAMA
                     RYVLRFPPAVALPREEVVAWLAPTVQRYLTAPHP"
     gene            complement(19881..20120)
                     /locus_tag="FNV62_RS19830"
                     /old_locus_tag="FNV62_20125"
     CDS             complement(19881..20120)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643174.1"
                     /locus_tag="FNV62_RS19830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_20125"
                     /product="hypothetical protein"
                     /protein_id="WP_054231770.1"
                     /transl_table=11
                     /translation="MDKKNALRAGALASGTTLMMLLMSSPALALTRDDGDDPGKGLSVI
                     ETLGLYVVTPIVLFLVIAGLVMVLDKSDKQPKRT"
     misc_feature    complement(21021..21038)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
ORIGIN
        1 gaacaacaac cacgacttca gcgacgacac cgcgatgaag ccgtacaagg acggctacca
       61 gatcggtcac ttcgggaccg acaacccggc caccgacgtc gtcgagagcc agccgttcgt
      121 cgtgcagatc cgcaaggacg tgccgatgga cccgtacggc gggtcctggg tcggcaagaa
      181 ggccgacttc gtcaacatcg gtctgatcgc gagcgagcac ggcacgcacg tcgccggcat
      241 cacctccgcg aacggcctgt tcggcggcaa gatgaacggc gccgcgcccg gcgcgaagat
      301 cgtctcgtcg cgcgcctgcg tgttcggccc gagctgcacc aacgtcgcgc tcaccgaggg
      361 catgatcgac ctcgtcgtca accacggcgt cgacatcgtg aacatgtcca tcggcggcct
      421 gcccgcgctg aacgacggca acaacgcgcg ctccgagctc tacacgcgtc tcatcgacac
      481 ctacggtgtc cagttggtga tctccgcggg caactccggc cccggcgcca acaccatcgg
      541 cgaccccggc ctggccgaca aggtcatctc ggtcggcgcg tccatctcca aggacacctg
      601 ggccgccaac tacggctccg tcgtggagaa gaagtacgcg atgatgccgt tctcctcgcg
      661 cggtccgcgt gaggacggcg gcttcacgcc gacgctgacc gcgcccggcg ccgcgatcaa
      721 caccacgcag acctggctgc cgggctcccc ggtcgcccag gccggctact ccctgccggc
      781 cggctactcg atgctccagg gcacctcgat ggcctccccg caggccgccg gcgcgtccgc
      841 gctgctgctg agcgccgcca agcagagggg catcgacctg acgcccgcca agctgcgcac
      901 ggccctcacc tcgaccgccg accacatcaa gggtgtgcag gcgtacgagg agggcgcggg
      961 cctcatcaac atcgtggacg cgtggaagtc gatcaaggac gacgtgaccg cccacgacta
     1021 caccgtcaag gcccccgtcg acaccgcgat cgactacgcc ctgaagaccc cgggcttcgg
     1081 caccggcctc tacgaccgcg agggcggcct caaggtcggc gtgaagaaga cgtacgacat
     1141 caccatcacg cgtacgtccg gcccggacaa ggcgatccgc cacgagctgc acttcgagaa
     1201 caacgccggt gacaccttcc ggatcgtcgg ctccgacgag gtcaagctcg aactgaacaa
     1261 gccggtcacc gtcaaggtcg ccgcgaaggc ctcctcggcc ggcatcaaga gcgcgatcct
     1321 cgaggtcgac gacccgcgga ccgagggcgt ggacaagcag atcctgacga cggtcgtggt
     1381 ctccacgccg ctcaagtaca gctactccgc gtcgagttcg gtgcagcgca acagcacgcg
     1441 gtcgtacttc ctgaccgtgc ccgagggcgc gaaggcgctg gaggtcgcga tcggcgggct
     1501 gaaggacctg agccagaccc ggttcatctc catccacccc tacggtgtcc cggtcgagga
     1561 caccggcacg ccgtactgct acagcaacta cccgaacacc aacggctgca agcccgacgt
     1621 gcgtgcgtac gcggacccgc agcccggtgt ctgggaggtc gaggtcgagg cgcgccgtac
     1681 ctcgccgctg ctcgacaacc cgtacaagct ggaggccacc gtgctcggcg cggccttcga
     1741 cccggccgtg gtgacggtcc ccgaggcgaa ggtcggcacg ccggtcaccg cctcctggaa
     1801 ggtgacgaac ggtttcgcgg cgctcgacgg caccctgaag ggcggcccgc tcggctcctc
     1861 gaagacggcc cggccgacca tcgcgggcgg cgccacccag accagcacgg tcgaggtgcc
     1921 ggccggcgcc gcgtcgctcg acgtcgccat cggcaacgtc tcggacacgg ccgccgacct
     1981 ggacctgacg gtgtacgact ccgcgggcaa gcaggtcgcg cagtccgcgg acggcgactc
     2041 ggaggaggcg gtctccatcc ccaaccccgc cgccgggacg tacaccatcg aggtcgtggg
     2101 ctactcggtc ccgtcgggct cgaccgcgta cgactaccgt gacgtgttct tctcctccgc
     2161 gctcggctcg gtcaaggtcg acgagtcggc gccggtgaag ctcgccacgg gcggtacggc
     2221 gacggtgtcc ggcgaggtca ccgcggccgc gccggccccc gagggacgcg agttcttcgg
     2281 ccgggtccag ctggtgaacg cccgcggcac ggccgccggc ctcggcagcg tgaagatcga
     2341 gaaggtcacg ccgtagcaac cggctgacat acgaggggcg ggcgtccgga aacgggcgcc
     2401 cgcccttctt cacgggcacg tgagggtgcg ggacgcgggc agcgccttca cgatccacgc
     2461 ccgttcgtcg gcgatggcct tgtcccccgt ggtccagccg gtcggtgtcg ccgggtcgcc
     2521 ctggacggcg acgagtaccc gctcgccctc acgcggccgg ggagccacct cctcgtccag
     2581 gacgaggacg acctcggccc tccccttctc gggcttgtag tagcggtcca cgtggagggt
     2641 gatccggttc tccgtggtgc cggggagagg ctcgacgtgg gcgaccgtgc cctccgccac
     2701 gagccgggcg caggccagat agccgggggc gctcagcgag gcaccgccgc ccgcggtccc
     2761 gctgtcggcc gccttggccc cgctggaatc cgacgcgcct gccccgttgt gcgcgaggat
     2821 ccagcctatg ccgacgacca tcgcggccac ggtggccgcg acgagggtgc ccaggaccag
     2881 ggctagggga cggcgcccgc ggttcctggg ggcgccttcg gggcggcggg tgcgcttcct
     2941 gggggcccgt accgggaccg gcttcgcttc ctgcgcacgg tccgccagcg cgtccccgat
     3001 gaccgccaac tgctcccgca gcagcgccac gtcggccacc gccgaccggt gctcggccag
     3061 gaactccggg tcgtcgccgg ccccttcggg cagagcctcg tcagtgatcg cggccaacag
     3121 cgcgtccact ccctcatact cggccacgtc acaccacctc gtcctcgtgc aggcgggcgc
     3181 gcagggcgcg gaccgccgag tgcagcctgc tcttgaccgt gccctccggg atgccgagct
     3241 cctcggcgat cccgcgcacg gacagatcgg cgtagaaacg caggacgagg acctggcgct
     3301 gggcgtcggg cagctcgtcc aaaccccgcg ccacggcgag cgagagcacg ctggagtcct
     3361 cgtcacgggc gtccgcgggc tgccgcagcg aggccagccg ctcgccgagc cgctcctggc
     3421 gccgcttggc ccggtgccag tccatcgcca ggttcgaggc gacgaccgcc gcccacgcgg
     3481 acacgtcacg cggcgcctcg tcccccttcg ccgcgcgttc cagcaaccgc aggcggacct
     3541 gctgcacccc gtccggcagg tccgcctgcg gtacgccacc gagcgcgagc accgcccgca
     3601 cccggcgttc ctgggccgcg tccaggggat cgtccgcccc ctggacccgg cgtgcctttc
     3661 tgcgcagcac tccgcccctc ccctcccgcg tttcctctac gacgccggtg cgagccaaaa
     3721 cgttcggccg cccgcgaagg agtcgtacgt cacaccgggc cggggccggt gaggacgccc
     3781 acgccgtacg gcttgcggtt cccggcggcc gacggacggt tttctttcgg atgccgcagg
     3841 aatgcccaag ggcggacgtg tcccattcct cgggcggcac gggcaaagga ttggacacgc
     3901 ggggacgggt cagacgcatg atggaagcgc tggaccacgt aaaacgcacg ctaagggagt
     3961 cgccgtgagg gtcggaatcg tcggagccac cggtcaggtc ggcacagtca tgcgcaggat
     4021 cctcgtcgag cggaagttcc cggtcgagga gctgcggctg ttcgcctccg cgcgttcggc
     4081 cggaaccgtg ctcgacggtg tgacggtgga ggacgcggcg acggcggact actccggcct
     4141 ggacatcgtg ctgttctccg cgggcggcgc gacctccaag gcactggccg agaaggtcgc
     4201 cgcgcagggc gcggtcgtga tcgacaactc ctcggcgtgg cgcaaggacc cgcaggtgcc
     4261 cctggtggtc tccgaggtga acccgcacgc gatcgccgac cgccccaagg gcatcatcgc
     4321 caacccgaac tgcacgacga tggccgcgat gccggtcctg aagccgctgc acgaggaggc
     4381 ggggctcgag gcgctggtcg tcgcgacgta ccaggcggtg tccggttccg gcctcgcggg
     4441 cgtggccgag ctgcacggcc aggtactgaa ggtcgccgcg gacgccgaca agctgaccca
     4501 cgacggcggc gcggtcgact tccccgagcc gggggtctac aagcgcccca tcgccttcaa
     4561 cgtgctcccg ctcgcggggt cgctcgtcga cgacggtctg cacgagacgg acgaggagca
     4621 gaagctccgc aacgagtccc gcaagatcct ggagatcccc gccctcaagg tctccggcac
     4681 ctgtgtccgc gtcccggtgt tcagcggcca ctccctccag gtgaacgccc gcttcgcgcg
     4741 tccgctgagc gtggagcgcg cgaccgagtt gctggccggc gccccgggcg tcaccctctc
     4801 cgagatcccg aacccgctcg aggccgccgg caaggacgcg tcctacgtgg gccgcatccg
     4861 cgccgacgag acggccgagc acggcctcgc cctcttcgtc tccaacgaca acctccgcaa
     4921 gggcgccgca ctgaacgcgg tccagatcgc ggagctggtg gcggcggagc tcaagggctg
     4981 acgcccgcgc cacatgcccc gggggcggtc accgcacggt gaccgcccct tctcacgccc
     5041 gccgcacctc gtagaggaag cacccgtact ccacggcccg tacgtggacg agcgccacct
     5101 ccgggtcggc gaaggcctcg tcgaaggcgt cgtcgaaggc ctcggggttc tcgaccagac
     5161 ggccgcccag gatgtggccc tcggcggagt agcggcggac cgtgcggtga gcgcccggga
     5221 aggggtggcc gcgcaggtcg gggcccgggc agtcgtcggc gtggatgaag accgggccct
     5281 gttcgtcgta cgcgcccggg tcgacgcccg tcccggcggc ccagcggcgc agcggcgcgt
     5341 aggagacgag ggcgatccgc tcccccggtt cactgcgccg cagacagcag cgcagcggcg
     5401 cgccgccctc ctcgtccgcg aagggaacca tcggacggtc cgcatcgtca gctgtgcgga
     5461 gatccttcag gaccgccggg tcgatgggac gtgccgtgta cgtcgtcgcg tatgtcgtcg
     5521 cgtatgtcgt catgtccgtc gtcgcgtccg tcgtgtgcgt catgtattca ggctcgcgcc
     5581 cgcgcgtgcc gggcaccggc gggaaacgga catcgcatcc gtgcaggtcc catggaagga
     5641 tggcgcaacc gtcacataac gaggagatga ccgcgtgcct ggcacaaacc tgacccgcga
     5701 agaggcgcag cagcgcgcga agctgctcac cgttgactcg tacgagatcg atctcgacct
     5761 ctcgggcgcg caggagggcg gcacctaccg gtccgttacc acggtgcgct tcgacgtcga
     5821 ggagagcggc tcggagacct tcatcgacct ggtggctccc gccgttcacg aggtgaccct
     5881 gaacggggac cccctcgacc cggccgaggt cttcaccgac tcgcggatcg cgcttcccgg
     5941 gctcctggag ggccgcaacg tcctgcgtgt cgtggccgac tgcgcgtaca ccaacaccgg
     6001 tgagggcctg caccgcttcg tcgaccccgt cgaccagcag gcctacctct acacccagtt
     6061 cgaggtcccg gacgcgcgcc gggtgttcgc gtccttcgag cagcccgacc tgaaggccac
     6121 cttccagttc accgtgaagg cgccgacggg ctggaccgtg atctccaact ccccgacgcc
     6181 cgagcccaag gacgacacct gggtcttcga gccgacgccg cggatctcca cgtacatcac
     6241 cgcgctgatc gtcgggccgt accactccgt gcacagcgtg tacgagaagg acggacagag
     6301 cgtgcctctc ggcatctact gtcggccctc gctcgccgag ttcctcgact cggacgcgat
     6361 cttcgaggtc acccggcagg gcttcgagtg gttccaggag aagttcgact acgcgtaccc
     6421 gttcaagaag tacgaccagc tcttcgtgcc ggagttcaac gccggcgcga tggagaacgc
     6481 gggcgcggtg acgatccgcg accagtacgt gttccggtcc aaggtgaccg acgccgcgta
     6541 cgaggtgcgg gccgccacga tcctgcacga gctggcccac atgtggttcg gcgacctggt
     6601 caccatggag tggtggaacg acctgtggct gaacgagtcg ttcgccacct acgccgaggc
     6661 ggcctgccag gcctacgccc cccagtcgcg ctggccgcac tcctggacga ccttcgccaa
     6721 ctccatgaag acgtgggcgt accggcagga ccagctgccc tccacccacc cgatcatggc
     6781 cgagatcaac gacctggacg acgtcctcgt caacttcgac ggcatcactt acgcgaaggg
     6841 ggcgagcgtc ttgaagcagc tcgtcgccta cgtcggcatg gacgagttct tcaagggcgt
     6901 gcaggcgtac ttcaagcggc acgcctacgg caacacgcgc ctcagcgatc tgctgggcgc
     6961 cctggaggag acctccgggc gtgacctgaa gacctggtcg gagaagtggc tccagaccgc
     7021 cggcatcaac atcctgcggc ctgagctcga gacggacgcg aacggggtca tcacctcctt
     7081 cgcgatccgt caggaggctc cggcgctccc ggagggtgcc aagggtgagc cgaccctgcg
     7141 tccgcaccgc atcgcgatcg gcctctacaa cctcgacgac gacagcggca ggctggtgcg
     7201 cgaccagcgc gtcgagctgg acgtcgacgg cgagctgacg gccgtaccgg agctggtcgg
     7261 caagcgccgc ccggcggtct tcctgctcaa cgacgacgac ctgtcgtacg ccaaggtccg
     7321 cctcgacgag gactcgctcg ccttcgtcac cgagcacctc ggcgacttcg agtcgtccct
     7381 gccccgtgcc ctgtgctggg cctcggcctg ggacatgacc cgcgacggtg agctcgccac
     7441 ccgcgactac ctgtccctgg tcctgtcggg catcggcaag gagtccgaca tcggtgtcgt
     7501 gcagtcgctg cagcgccagg tgaagctggc gatcgagctg tacgccgacc cgacggcccg
     7561 cgaggcgctg ctgacccgct ggacggacgc gacgctcgcg cacctgcgcg ccgccgagcc
     7621 cggcagcgac caccagctcg cctgggcgcg tgccttctcg gcgaccgccc gtacgccgga
     7681 gcagctggac ctcctggagg gcctgctgga ggaccgggag agcatcgagg gcctcgccgt
     7741 cgacaccgag ctgcgctggg cgttcgtcca gcggctcgcg gcggtcgggc gctacgacga
     7801 ggcggagatc ggcgccgagg cggagcgcga caagacggcg gccggtgagc ggcacgcgga
     7861 gacggcccgg gcctcgcgtc ccaccgagga ggcgaaggcg gaggcctggg ccgcggtggt
     7921 cgagtccgac aagctcccga acgccgtgca ggaagcggtg atcggcggct tcgcccagac
     7981 cgaccagcgc gagctgctcg ccccgtacac ggacaagtac ttctccgtgg tgaaggacat
     8041 ctgggacgcc cgttcgcacg agatcgccca gcagatcgtg gtcggtctct acccgtccgt
     8101 ccaggtctcc gaggagaccc tcgccaagac ggacgcgtgg ctggccgcgg ccgagcccac
     8161 cccggccctg cggcgcctga tctcggagtc ccgctccggg atcgagcgcg cgctgaaggc
     8221 ccaggcggcg gacgcggcgg cggcttccgc gtagtcggtc gtacgtgaat gggggctccc
     8281 ggcgtcgtgc cgggagcccc ctttcgcatg agcgcgcgcg tgggcgtgtg tgagtgcgtg
     8341 tgggcgtgtg tgggcgtgtg tgggcgcccg gggtcacacc agggcgcggg cgagtgcgag
     8401 catcgtgcgg atctggagct cggtctggtc ggtcacgggg acccagcggg cgtcgaaggt
     8461 actggccagc tcacgtgccc aggcctccac gagggtgtcc agcgcggggg cgccgcccag
     8521 ggcctgccgc atcatggccg ccgcgcgcag cgggatgcgc cgggcggcga cgccgagcga
     8581 gacggcgttg cccacggtgg tggcgagttc ggcggagttc caggtgtcca cgactccggg
     8641 gccgatgtcc atgagctcac gggcggcggt gaagtgggcg atctcctcgg gggtctcagg
     8701 tgccctgggc cccagctccc ccaccaccgc ctccagttgt ttggcccggc cgagcaggat
     8761 ctcgctcgcc tccgcgacct cgcgccgggg ctcggcgacg ggccgaggat cgctgacgcc
     8821 ggccacgctc cagaagggcg cctcgacgac cgccgacacg gttccgtgcc gcatcgcgta
     8881 cagccaggtc gcctgtgagg tgaagccgga cgggtcccgt tcctcggtgg ggccgctgtc
     8941 cggcaggacg agcacgcccg ggctctcggc cagccatccc atgccgtcga acggccggtg
     9001 ttccaggggg atgccgaggt ccgccgcgat ccgacggtag gcggccgccg cccccggcac
     9061 cgcgcgagtc aactgcagaa aggatccgcc cacttcgacg ccgtggagcg agaactgcac
     9121 gaccgggcgc agttcgtcga tgagccgcac cagcgcctcg gactccggca tcaccggacg
     9181 cgggtcactg gtgacgggcg gaaactcggg ctgcgcggcg aaggcgggcc ggtagaagcg
     9241 ccggtagtaa ccccggaggg tcggcgaggc ctcggccgcc gcccgaccct cgccgggcag
     9301 cccctcgcca ggcagcccgg tcagccatcg cccggcgagg ctcgcgccgt cggggtcgag
     9361 gcagagcagg aagttccagg tgcagccgga ctcctggagc agcgcgggct cccgcgcgaa
     9421 cctctcggcc agggagagcg aggtgacccc gcccaccggt tcgttggcgt gcgcgccggc
     9481 gaccgtgagg atgtgccggg ggccgtgtcc ggcggacagc agccacagcg gccggccggc
     9541 acgcgaggtc ccgacggcac gcaaccgcag tgcaccgggc cgtgccgcca ccgtcgcgcg
     9601 agcgcgtcgc agcagctcac cgagggtggg atacggggtt ccccgcatgc cgggctccgg
     9661 tcaggtgccg ttcgcgttgc tgtccccggt ggtctccttc ttgtccagcg gacggatcac
     9721 gatcttggcg gccatgtggc cccctctctg tgtgggctct gcggtggccg agttcctgtc
     9781 cggcgaaacg gatcagccgc cgttgcctcc gctgctgtcg cccgtggtct ccttcttgtc
     9841 caacgggcgg atcacaatct tggtgggcac cccaactcct ctcgtcagta gggacgttga
     9901 gcgttgcggg cgcgatcgcc gaccgcgtct tgtcaaggct cgactcgggg gaccagagtg
     9961 tcaaggcatg tacctgtaac gggaaggggt cctggtgacg gtgccggtcg acacgctccg
    10021 caggccccgg atcaagcccg agcaccggcc gtaccgcacg atcgacggca acgtccgcat
    10081 cggcagcgtc atccacggca tcggcgccga gatcgaggac ccgcagggct gggtctggac
    10141 gctggtcgag gcgatggacg gaacgcggga gccgtcggcg gtggtcggcg aggtgctgag
    10201 ggcgcatccc gaacttcccg acctcacgtc cgaggacgcc cggcaggcga tggcggacct
    10261 gctcgacgcc gggttcgtgg aggacgcggc ggcgcccgtg ccggtgtccg agcgggaacg
    10321 gctgcgctac agccgggggg tgccgctgct gcgctggatg gacctcggcc cccggacgag
    10381 tccctgggac gcccagctcc ggctgcgccg ggcccgggtg ctgctggtcg gcgtcggcgg
    10441 cacgggcggg tacgccgcgc agggcctggt cgcctccggg gtcggccgtc tgcactgcgt
    10501 ggacccggac gtggtggagc tgtccaacct caaccgccag cccctcttcc gcgagtccga
    10561 cctcggccgc ccgaaggtga cggccgcgct cgccaccctg cgggcgctga actcggacgt
    10621 gacggtgacc ggggaacgcc gggagatacg acacccggcg gaactggcga ggctgatacg
    10681 gaccggggca cccgaagccc cgagcgaacc gaaacgggcc gggacgcccc aagccccgag
    10741 cgaaccgaca cacgccggga cgcccgaagt cccgtactcg tcgcggagct cgtacgacct
    10801 tctcgtcctc gccgccgacc gtcccgacga catccgccgc tgggcgaacc gtgtctgtct
    10861 ggccgcggac ctgccctggg tcgacgccgg ctaccgcggc cccctggtga cggccggggt
    10921 ccacgtaccc ggccggggtg cctgctggga gtgtctgcgg gccggtgagg tggcccgccg
    10981 cgagctgcgc ctggcgcccg gccaggacga cggggtcgcc tccccgcacc tgccgtggaa
    11041 ccccgcgacc gcggtcaccg cgggcctgtc cggcggactg ctcgcccacg cggccctggc
    11101 cctgctgacc ggcgtcccgg cgctcgaccc cggcttccgt ttcgggatga acctgatgct
    11161 gccgggcgac ccggtgctgc agagattccc gcggcgaacc gactgcccgg cgtgcggcga
    11221 cagacccgac gacggagcca ccggcgcggg cggagcgacc ggaccgggcg gagcgaccgg
    11281 accggctggg gagcgcgcgt gaaccacgtg cgcctgcacg ccctcgactc ccgccccgac
    11341 ggcgacgagt ggatcgtcgg ccggctggcg acgggccggt tcgtcgcgct gcccgaggtc
    11401 ggcaagcagg cgctggacct gctcgggcag gggctgagca ccaccgaggt cgaggagcgg
    11461 ctgcgggaga ccaccggcga cgacatcgac gtacccgact tcgtcgaggc gctggtggac
    11521 ctcgggttcg tcgccgaggt ggacggacgg gaagtggcct cgccgccccc gccgaagccg
    11581 acgctcgccc ggatcggtcc ccgccatgtg cgctgggtcc tcagcccggc cctgcccgtc
    11641 ctcatcgccc tgctgatcac caccaccctg ctcacccgcc cacccgttcc cctcggctac
    11701 cgcaccctcc tctggagccc gcacggcagc gcggtgatcg cgctcggcgc gggcttcggc
    11761 tggacgctcc tgctgctcca cgagtgcgcg cacctgatga ccgcccgggc gaccggcgtg
    11821 cccggccgga tgcgtctcgg cacgcgcctg cagttcctgg tcatgcagac ggacatcagc
    11881 ggcatcgaac tcgctccgcg ccgccatcgg ttgaccgcct acctcgccgg gatcgccacc
    11941 aacctcaccg tcgcctccct ggccgccctc gccgcgggcg ccacgcacgg caccccccgc
    12001 cggatcctgg ccgccgtcgc cctgctcgcc ctgctccccc tccccttcca gctcatggtc
    12061 ttcatgcgta cggacctgta cttcgtgctc caggacgtga cgcgctgccg tgatctgtac
    12121 ggggacgggg tggcgtacac gaaatacgcg gcacggcggg cgctgcgccg taccaccgcc
    12181 ccggacccca gcctcgaact ccccgcccac gaacggcggg cggtgcgcgc gtacagcgtg
    12241 gtgctcgtcg tcggcaccac gctgtgtctc gtgttcctcg cgaccgtcac cctgcccgcg
    12301 gacatcacgc tgttcgcccg cgcggtggcg cacctgggcc ccggccactc ccccgccgtg
    12361 cgcctcgacg cgacggccgt cgtggtcgcg ctcggcgggg tgcatgtggt gtgggcccgc
    12421 acgtggtggc gcgaccgccg cggccgtcgg tcctcgtagc cggtcctccc agccggtcgt
    12481 cccaaccggt cgtcctagcc cgggaacatc ccgccggtga cgttgacgaa cgtgccggtg
    12541 atgccgcccg cgtggtcgga ggcgaggaag gcggcggtcg cggcgatctc ggggagggtg
    12601 ggattgcggc gggtcatgcg cattccggcc aggttcgcga gcaggccctg gagggcgttc
    12661 tcgtcgaggg ccatggcgct gtcgaccgcg gcgagcttct cgcgggtcag cgtctcgggc
    12721 acgccggccg cccacagacc cacggcccgc accccgcgcg gacccagttc catcgccagg
    12781 ttgcgcacca gcgtgtcgat cgccgcgtcg gccgggcccg ttccgcccat catcggactg
    12841 ccgtgcgccg aaccgctgtt gagcgtgagg accacgccgg agccccgctc ggccatacgg
    12901 cgggcggcgg cgcgggcggt gacgacgttg gcgcggatac cggtgacgac cggacgtacg
    12961 aagtcgtcga cggacatgtc gagcagcgag gcaccctgca catcaccccg ggtgacgagg
    13021 ttgaaggaga tgtcgacggc gtccagcgac gcgatgtgcg cctcgaccgc cgcctcgtcg
    13081 agcgcgtcga cgaccgccgt cccggcgtgg ccgccctccg cctcgatgtc cttggccacc
    13141 gcgtcgagcg tcgccgccgt acgccccacg aggtgcacgt gggcaccctc gcgggcgaag
    13201 gtacgggcga cggcgccgcc gatggatccg ccggcgccgt agatgaccgc ggtcttgtcg
    13261 gtgagcagca tggtgaacct ccgtgaggtg ggttgtcgga acggcccgta tgaatcggcc
    13321 ggaccagtcg gccgtacgag tcggtcatgc agacgttcgc accgtctctc actcatcggt
    13381 cggcgggcag ccgcagcggc agtccgaacg ccgggaagag atgcggctcg aaggaggtga
    13441 tctccacgat ccggtcgccc tcgacacgga ggacgtcgag gacctgcgcg cggtagacgg
    13501 tcgtacccgg gcgccggacg taccccccgg ccgcgagctg tccgttggcg cgggcgggca
    13561 ggtggcgcca gtggccgagg aacatcgggg aggccgggtc gaggctgacg gacaggaact
    13621 cgacgagcgc ctcgcggccg acgaaccaga acgggttcgg cggcatggtg agcgtgatgt
    13681 cctcgctgag cagggtggcg acctcggtga ggtcgaggcg ttcggcggcg gccatgtaac
    13741 gcgccaggat ctcgcgctca cggacgtccg cctccgcggt ccactcggcg cgacggcggg
    13801 gcaggtggtc gcgcagggtg ggccgggccc gttgcagcgc gctgttgacc gaggcgaccg
    13861 tcatgtccag taccgcggcg gtctccgcgg cggccagccc caggacgtcg cgcaggacga
    13921 ggaccgcgcg ctggcggggc ggcagatgct ggatcgcggc gaggaagacg agctccaggg
    13981 tctcccggga gaccgcgagc gcgtcgggct gctcttcggt cgagggcagg tcgtcgtcgg
    14041 ggtagggctg gagccaggtg acgcgggccg ggggctcggc gccgccgtgg ttcatcccgg
    14101 gcagcggctc gtaccgctgc gggcggcgcg ccgtgcgccg ctggaagtcc aggcaggcgt
    14161 tggtggcgat ccggtacagc cacgtccgta cgctcgcccg ccccgcgaac ccgtcccggg
    14221 cccgccaggc ccgcaggaac gtctcctgca cgaggtcctc ggcatcgtcg tacgagcccg
    14281 acatccggta gcagtgcacg cgcagttcgc gccggtagga ctcgacgagc gcggcgaagt
    14341 cgctctccgc gagggccact tccgtaacgg ggccggtcgt gacgagatcc accgcgccgg
    14401 gctcgcccat gacgggctcg tccaagacgg gctcctccgt cacggggtcc gccgtaccgg
    14461 gacctgccgt gtcgcgggcc gtccgggcga tgcgccgcag ccgtcccacg gaggcggcca
    14521 gctcgctcac cccggagtag aagacggcgg gcggcgccgg gaccagctca cggacctgcc
    14581 gcccgacctc ctcgatgagc ccctgggcgg tgtccgaggg cgccgcccgc cgctcccggt
    14641 acgccctctg ccgacaggcg gccgagcagt acacggaact ccgccccttg cgcccggtcc
    14701 gcccggccag cggcttcccg cacccaggac acacgccgtc gaccacagga acctccagga
    14761 atcgcggaat cgggggagtg ggggatcggg gcatggggaa tcggggaatt acgtcacgcg
    14821 cggacgacgt gacgttatcg ccgctccccc agccccgcag ccacctcccg caaagcctcc
    14881 gacgggagcc ggccgcccgc cacgcggccc gacctggccg agcaccgtcg ccccgaacgc
    14941 cagtaccatc cccgccacct gcaccggcgt cagcgactgc cccagcgccg cccagccgat
    15001 gacggccgcg gtcagcggtg acagcgggcc gaggaaggtg acctgggtgg cgctgagccg
    15061 gccgatgccc cggaaccaga gccagtacgc caccgccgtg ttcgccagcg cgaggtacag
    15121 gtatccgccg accgcccggc cgtccagcgc gggcggcgcg ccctcgacca ggagggcgac
    15181 agggacgatc agcagcccgc ccgccgtcaa ctgccaggcg gtgagcgcca acggaccgac
    15241 cccgtccggc cggccccacc gcttggtgag caccgtgccg gtggacatcg acgcggtcgc
    15301 ggcgagcgcc gcgaggaccc cgaccgcgtc cagcgcgccc gccgcctgca gcacgacgag
    15361 gctgacaccg agggccgcgg caataccggt gaggagcgtc cgcagggtcg ggcggtcacc
    15421 gagcagcagc gccgcgaggc ccgcgacgaa cagcggcccg accgagccga cgaccgccgc
    15481 catgccgccg ggcagccgat acgcggagag gaacagcagt ggaaagaagg cgccgatgtt
    15541 cagcgcgccc agcagcgccg ccttccccca ccaggcgccg cgcggcagca cccgggccag
    15601 cgcgaggagc agcagcccgg cgggcagggc gcgcatcacc ccggtgaaca gggggcggtc
    15661 ggcggggagg aactccgtgg tgacggcgta ggtgctgccc caggagatgg gggccagcgc
    15721 ggtcagggct atgagggcgg gacggttcgc gttcgcggcc atggtgagca cccgattcca
    15781 aagtaggtca atggaaagta gcttagctcc aagtgactta tggtcaagct acttcctcgt
    15841 cagctacttt cttgcgggca atcgacccct cggcggatac tcgcccccat gaagacgccc
    15901 caggacccgg tcgacgcgat catcgagcag tgggccaccg tccggccgga cctcgacacc
    15961 gccgcgatgg aggtcttcgg ccgcgtcttc cggctcgccc gcacgatggg cgaccggatg
    16021 gagaaggcgt acgcgcccta cgggatctcg cgcggggagt tcgacgtgct cgcgaccctg
    16081 cgtcgctcgg acgccccgta caccctctcg ccccggcagc tctcggcgac gctcatgctc
    16141 accaccggcg gcatgaccgg gcgcctggac aagctggagc gcgcggggct gctacggcgc
    16201 tcccccgacc cgcacgaccg gcgcggactc caggtgacgc tcacggacaa ggggctgcgg
    16261 ctcatcgacg aggccgtcgg cgcgggactc gccgtccaga cggaggccct ggcccacctc
    16321 gacgaggaac gagccggtca actggccgcc ctgttgcgcg agttgctgat gggcgccgga
    16381 gcctagggtc tcggcgggcc cccgagcccg gcccggaggg cctcagcccg ccgcggcgac
    16441 ccggctcgac ctgacgcgta tcacggtgag ccgccccagg acctgagcca gcgccatcag
    16501 cagcagcgcg gcggtccagg cggcggaacc ggtgatcagg ttgtcctggc tgaaccgcgc
    16561 caggctcccg gaaccgccat gagtggccca gtactcgaat ccggcgcgcg aggccatgcc
    16621 gacgatccac aggagcgcgg cgagtgcccc ggcgcgggcg aacgcgatcc cgtccgaggc
    16681 gcggctcagc cgggtggccg cgccacaggc gacgcccagg accgcgccgg cgacgacacc
    16741 ggcgatgtcg agtccgacgt cgtgcccttg ggtcgggaag gacttgaggt aataggcggc
    16801 tgcggcggcg acggccgcga gcggcagcag cgtgtggtgc agcgtctgcc ggacgcctcg
    16861 gatctgcggg atcacgagga ggatgaggga tgcggagatc acgtagtcgg tcgtcgtcat
    16921 gcccatgagc ttgcgcttca cgacgcggaa ccacctcggc tccagggtgg agccgagggt
    16981 gggtttccgc ctcaacccac gggttgagat ccaggatccg tcttcagtga tccttggatg
    17041 agggtggcgc cactggccgg ggtcgccgtc gccccgctgg tcgtcgcagt cgtagtacac
    17101 gtactgatcg atgtccagcg acgccccggc ccgggcgagc caggccagca gggccgcgcc
    17161 caggaagatg ccctccggct cccgcttcgg ggcgggtccg gtcgccgcgg ccgtgcccgc
    17221 acctacagtc aggcacaagg cggtcgcgag cgtgacgatc ttctgtttta cgtgcaggta
    17281 catgcgttcc tcagggcgcg gacccccagg cgtcgttcga cggcgcgggt ccgcgcttcc
    17341 cccgggcggt cgaaccaccc tcgtgttgcg tatacgtcaa acgcatggcc gaaatcaccg
    17401 taaaccgtta ccaacggtca tgctcaactc agcgtcccac gcggtggcat accgctcccg
    17461 acgcggtgtt gagatgccgg cgtttccacg gagcggcggt caccctcgcg tcactcccgc
    17521 cccgggcaag gtcagttcga agacggatcc tcgcccagcg ccgccgccaa cgcccgctcg
    17581 acggccgccg cgtcggggga ttcggcggcc caggccacgt atccgtcggg ccgcaccagc
    17641 agggtcgtac gccggtcgct cgcccagctc tccacggcga gacggtcctt gcggcccttg
    17701 aggtcgtcca ggccgtacgc ccggacggcc gccgtcggtg cgacgaggac gaaccggccg
    17761 ccgcgcaggg cctcgtagag gcggccgccc ttcagagtga catcgggggc ccgggtgccg
    17821 acgagggcgt gcgagccgcg cggggcccgg taggcgaagc cgatgccggt gatctggccc
    17881 gccgccttcc ggcgcacggg gccgacgccg ttgaggaccg tggtgagcac ggagcgcagc
    17941 gccagcgtcc aggggtactt ggccatcgcg agccggacga tcccgccgct gctgcgcagc
    18001 accgccttgc cgacggggtg gcgctcggcc tggtaggtgt ccaacaagtc cgtgtccgca
    18061 tggccgttga cgaccagcgc gagcttccag ctgaggttcg ccgcgtcctg gaggccggtg
    18121 ttcatgccct gcccgccggc cggggtgtgg acatgggcgg cgtcaccggc gaggaagacc
    18181 ctcccgaccc ggtacgcggg cgcctggcgc tcgtcgctgt ggaagcggga catccagcgg
    18241 gcgtcgtgca tgccgtagtc atggccgagg gagagccgga cgatctcctt gacctcgtcg
    18301 agttcgagcg gcgcgctgtc ggggacgtcg cgaccgcggt gccagccgat cacacggtag
    18361 tagccgtcgc cgaagggcac catgaaggcg aaggcgtcgc cgacggcgtt ggcggtgagg
    18421 atcgactccg gctcctcggc gagcaggacg tcggcgagga cgacggaccg gatgaccgac
    18481 ttcccgggga acggcagccc caccgcctca cgcaccgcgc tgcgcatccc gtccgccccg
    18541 accacgtacg cggccgccat ctcccccgcc gccccgtccg caccgcggac ttcgagcgtg
    18601 acgcccgccg cgtcctggcg cagtccggtc acctcggtct cgtacacgaa ccgcaccccg
    18661 gcctcgaccg cccgccgctc caacgcccgc tccacctcgt actgcgggat cacgagcagg
    18721 tggttgaagc gggaggggag cgtgtcgagg gcgacggaga gcccgccgaa gaggcggatg
    18781 cggtcgacgg tccggccgtg actctccagc tcgtcggcga gaccgcgggc gtcgagctgc
    18841 tccagggtgc gggcgtgcag gacgaaggcg cgggagaggt tgctgatccc gtgcgggcgc
    18901 ttctcgacga gggtgacggg gacaccggcg gcggcgaggt ccccggccag caggaggccg
    18961 gtggggccgg agccgacgac gatcacgtgc cgggacccgt tggtgccgtt caccttgccg
    19021 ttcgtcttgc cgttcatggc ggcctcctga tgccaacgtc cgttggtcaa catttgttgg
    19081 ccaacgcttg tttaccaaga tagggagccc gctctggact gtcaacaact gttggcctac
    19141 ggttgttggc atgcccgaca aggaactccc cgcacccgcc gcgtcccccg cggcccgccg
    19201 ttcggacacc acccgcaccg ccatcctcac cgccgcgcgc gaacgcttcg ccgccgacgg
    19261 ctacgagcgc gccacgatcc gctcgatcgc caaggacgca cggatcgatc cgtcgatggt
    19321 gatgcggtac tacggctcga aggaaggact gttcgccgcg gtcctcgacg tcgacctgcg
    19381 gctgccggac ccggtcgggc tggacccgca cgaggtgggc cgcgccctgg tgggccactt
    19441 cctcgacctc tgggaggaga acgaggtcct caccgtgctg ctccgggtcg gcgtgaccaa
    19501 tccggacggc gccgcgcgca tgcagggcat cttccgggac cagctcatgc cggtcgcgct
    19561 gcgcgtgtgc cccgacccgg agcaggcgcc ggcacgggcc gcgctgaccg cctcacaggt
    19621 gctgggcatg gcgatggccc gctacgtcct gcgattcccg cccgccgtcg cgctgccccg
    19681 cgaggaggtc gtggcgtggc tggcgccgac ggtgcagcgg tatctcacgg cgccgcatcc
    19741 gtaacgggcc ccgaaagccc gtcgagggac tccgaaaaca cgtcgaggga gtccccacac
    19801 ccggtaggtg cgcggactcc ctcggtcgag aaggatccag gcctcggcgc gcggccgggg
    19861 ctccaggaag cgagccggaa tcaggtccgc ttcggctgct tgtcggactt gtccaggacc
    19921 atcacgaggc ccgcgatgac caggaacagg acgatcggcg tcacgacgta gaggccgagc
    19981 gtttcgatca cgctcaggcc cttgccgggg tcgtcaccgt cgtcgcgggt cagcgcgagc
    20041 gcgggggacg acatgagcag catcatcagc gtcgtaccgg aagccagggc gccggcgcgc
    20101 agggcgttct tcttgtccac ggtgcaaacg tagcgaacac ctgaatgagt cgcgcgcccg
    20161 gggtgccgta cggaggccgc acccccgccc ggacgccccg ctcacgcccg ctcacacgcc
    20221 tccgtcacgc ccacgcgcac tcccaccctc accccggcca tcgctgcggc ggtcatcgct
    20281 cccgcggcca tcacgtccac cgcgaccccc ggaccgtccc cgcagcacgt cgatcagcgc
    20341 gtacagccgg ggcgaggccg ccagttcctc cagggtcacc gggcggcctt ccgcgtcggc
    20401 gatgggcagc cgccagttcg ggtactggtc ccacgtgccc ggcaggttct gcggacgccg
    20461 gtcgccgacc gtgtccggga gccacacgcc gatcatgcgg gccggggtgc gcagcaggaa
    20521 gcggtgcacg gcctggatct cggcctcctc cgacaccgcc gaacccgcgt cgcccgcccc
    20581 gtgcagcagc cccaggcggg cgagcagcgc cagccactcc cccgtgtccg ccgtggccgc
    20641 ggtccgctcg tcctccaggg agccggtcag caggccgagc cggtcgcgga gttcgacgtg
    20701 gtcgccggtg agccgggagg cggtgggcgg caggtcgtgg gtggtggcgg tggccaggca
    20761 gtcggggcgc cagcgctcgg ggggcagggg cttcccgtcg ccgtcccagt cccgttcgaa
    20821 ccacagcacc gaggtgccga gcaccccgcg ctcgtgcagc gtctcgcgta cgccgggctc
    20881 gaccgtgccg aggtcctcgc cgatcaccag ggccccggcc cgcgaggcct ccagggtcag
    20941 gatcgcgagc atcgcctcgg cgtcgtagcg gacgtacgtg ccctcggtgg gcggctgtcc
    21001 ctgcggcacc caccagagcc ggaacaggcc catcacatgg tcgatgcgca gggcgcccgc
    21061 gtgccggagg agggcgcgca ggaggcggcg gtacggggcg tagcccgagg cggcgaggcg
    21121 gtccgggcgc cagggcggca ggccccagtc ctggccgcgt gcgttgaagg cgtccggggg
    21181 cgcgccgacg gacatgcccg ccgcgaagta ctcctgctgc gcccaggcgt cggctccgcc
    21241 gggatgcact ccgaccgcga ggtcgtgcac gaggcccacc gccatcccgg cgtcgcgcgc
    21301 gg
//
