LOCUS       NZ_CP041610            21944 bp    DNA     linear   CON 14-NOV-2023
DEFINITION  Streptomyces sp. RLB3-17 chromosome, complete genome.
ACCESSION   NZ_CP041610
VERSION     NZ_CP041610.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RLB3-17
  ORGANISM  Streptomyces sp. RLB3-17
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/14/2023 04:19:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,027
            CDSs (total)                      :: 10,924
            Genes (coding)                    :: 10,421
            CDSs (with protein)               :: 10,421
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 503
            CDSs (without protein)            :: 503
            Pseudo Genes (ambiguous residues) :: 0 of 503
            Pseudo Genes (frameshifted)       :: 178 of 503
            Pseudo Genes (incomplete)         :: 409 of 503
            Pseudo Genes (internal stop)      :: 52 of 503
            Pseudo Genes (multiple problems)  :: 128 of 503
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1573507
            Orig. end                         :: 1595451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041610.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041610.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21944
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="melanin"
                     /region_number="10"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..21944
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(340..354)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.13"
                     /tool="antismash"
     misc_feature    complement(918..932)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            956..1822
                     /locus_tag="FNV62_RS07575"
                     /old_locus_tag="FNV62_07715"
     CDS             956..1822
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471149.1"
                     /locus_tag="FNV62_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07715"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_144314891.1"
                     /transl_table=11
                     /translation="MAATLDTPQRPRGFAARGRRGALGLLAWLCGTVFFLPVAWMVLTS
                     LHRESDAATNPPSLGAPLTLQGYREFFGASTGVSPWPPLINSFSASLMSTLLVLVLSIP
                     AAYALSIKPVRKWTDVMFFFLSTKMLPVVAGLLPIYLIAQNSGMLDNVALLVVLYTSMN
                     LPIAVWMMRSFLAEVPVEILEAASIDGAGLPTVLARIVAPVVAPGIAATSLICFIFSWN
                     ELLFARVLTGVVAGTAPVFLTGFVTSQGLFLAKVCAAAVCISLPVLIAGFAAQDKLVQG
                     LSLGAVK"
     gene            1819..2808
                     /locus_tag="FNV62_RS07580"
                     /old_locus_tag="FNV62_07720"
     CDS             1819..2808
                     /NRPS_PKS="Domain: PKS_ER (14-262). E-value: 1.6e-12.
                     Score: 39.2. Matches aSDomain:
                     nrpspksdomains_FNV62_RS07580_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957246.1"
                     /locus_tag="FNV62_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07720"
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_144314893.1"
                     /sec_met_domain="ADH_N (E-value: 1.9e-34, bitscore: 117.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.8e-17, bitscore:
                     60.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAAVISSPGQVGVETVDDPTPGPGQVVIEVSACGLCGTDLHILQ
                     GEFAPTLPIIPGHEFAGEVVALGSGVRDLKVGDRVAVDPSLYCHECHYCRIGRGNMCER
                     WNAIGVTVPGGAAQYTAAPAANCVKLPEHVRTEDAALIEPLSCAVRGYDILRSTLASNV
                     LIYGSGTMGLMMLELAKRTGAATVDMVDINEDRLATARTLGCSNAVTTADAIERPRGWD
                     VVIDATGNAHAIQDALSRVGKGGTYLQFGVADYATRATIDPYRIYNQEITITGSMAVLH
                     SYERAAELFAGGVLDPEIFISDRLPLADYAEAVRQFQAGKARKIQVLP"
     aSDomain        1861..2604
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV62_RS07580_PKS_ER.1"
                     /evalue="1.60E-12"
                     /label="FNV62_RS07580_PKS_ER.1"
                     /locus_tag="FNV62_RS07580"
                     /protein_end="262"
                     /protein_start="14"
                     /score="39.2"
                     /tool="antismash"
                     /translation="ETVDDPTPGPGQVVIEVSACGLCGTDLHILQGEFAPTLPIIPGHE
                     FAGEVVALGSGVRDLKVGDRVAVDPSLYCHECHYCRIGRGNMCERWNAIGVTVPGGAAQ
                     YTAAPAANCVKLPEHVRTEDAALIEPLSCAVRGYDILRSTLASNVLIYGSGTMGLMMLE
                     LAKRTGAATVDMVDINEDRLATARTLGCSNAVTTADAIERPRGWDVVIDATGNAHAIQD
                     ALSRVGKGGTYLQFGVADYATRATID"
     gene            2805..3566
                     /locus_tag="FNV62_RS07585"
                     /old_locus_tag="FNV62_07725"
     CDS             2805..3566
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012515.3"
                     /locus_tag="FNV62_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07725"
                     /product="carbohydrate kinase"
                     /protein_id="WP_225900193.1"
                     /transl_table=11
                     /translation="MTGRLPPLVIGEALVDIIAGPDGPRRSHPGGSPANVALGLGRLGH
                     PVRLATRVGNDPHGRLVREHLEGSGVELAPGSVVGIATSTATAVLDDTSAANYAFDLTW
                     ALPAAVEESLRDGPPAHVHTGSIATALAPGADQVLSALHGLRASATVSYDPNLRPALLR
                     SGERERERVEQLVALSDVVKASEEDLAWLHPDVDPDRTAARWARNGPALVVLTLGADGA
                     RAWWRHGCQDIAPLPVRVTDTVGAGDASWPD"
     gene            3554..3772
                     /locus_tag="FNV62_RS55555"
     CDS             3554..3772
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS55555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143600421.1"
                     /transl_table=11
                     /translation="MAGLTSGLLHAGLLGGGAEAEAATARAALRAATETDRLPTALAAA
                     LAVAARAAALTCAREGANPPAAAELMV"
     misc_feature    3778..3792
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.27"
                     /tool="antismash"
     misc_feature    3854..3864
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(4417..4432)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.82"
                     /tool="antismash"
     misc_feature    complement(4473..4487)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     misc_feature    4474..4488
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.16"
                     /tool="antismash"
     gene            4594..5763
                     /locus_tag="FNV62_RS07590"
                     /old_locus_tag="FNV62_07735"
     CDS             4594..5763
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373328.1"
                     /locus_tag="FNV62_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07735"
                     /product="glycoside hydrolase family 64 protein"
                     /protein_id="WP_225900824.1"
                     /transl_table=11
                     /translation="MAVAAATATTALLTFGAPSDANAAVPATIPLKFTNNSGRSEPVYI
                     YDLGTLLSTGQQGWADANGTFHAWPAGGNPPTPAPDASIAGPANGQSMTIRMPKFSGRI
                     YFSYGQKLDFRLTTGGLVQPAVQNPSDPNHNILFNWSEYTLNDSGLWINSTQVDMFSAP
                     YAVGVQLADGSTKNTGHLKAGGYTGFFNALRGQPGGWANLIQTRSDGTVLRALAPGHGI
                     EAGALPGTVMDDYVNRVWQKYSSSTLTVTPFTDQPNTKYFGRVSGDVMNFTNSAGAVVT
                     SFQKPDSDSIFGCYKRLDAPNDLVRGPISRTLCAGFNRSTLLTNPNQPDTSSASFYQDT
                     VTNQYARKIHAQMADGKAYAFAFDDVGNYESLVHDGNPQQAYVTLDPFN"
     gene            complement(5778..6443)
                     /locus_tag="FNV62_RS07595"
                     /old_locus_tag="FNV62_07740"
     CDS             complement(5778..6443)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127583.1"
                     /locus_tag="FNV62_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07740"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_060897528.1"
                     /transl_table=11
                     /translation="MSTPLPPFPRGQEPSGAPVPLELTVGPAAPQLRADAARNRARLLE
                     AATRLVEEHGVANVTMEAVAAAASVGKGTVFRRFGDRTGLLMALLDHTEQQFQAAFLSG
                     PPPLGPGAAPADRLHAFGCRVLREIHDRLDLYLAAEPDASRRFSSAPYRVRFTHVVMLL
                     REAVPGADGVLLAQTLMGYLEPALIHHLTRQCGMPLERLESGWHDLVKRTTCPVPDRP"
     gene            6571..7134
                     /locus_tag="FNV62_RS07600"
                     /old_locus_tag="FNV62_07745"
     CDS             6571..7134
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117016.1"
                     /locus_tag="FNV62_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07745"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_054236861.1"
                     /transl_table=11
                     /translation="MSVRILALVGSLRAGSHNRQLAEAAIKLAPEGAEIELFEGLAEVP
                     FYNEDLDVEGKVPAAATALREAAGRADAFLLFSPEYNGTITAVLKNAIDWLSRPYGASA
                     FTGKPAAVVGTAFGQFGGVWAQDEARKALGIAGAAVLEDLKLSVPGSVTRFAETHPVDD
                     AEVAAQLTEVVARLHSQVGTASAS"
     gene            7269..7946
                     /locus_tag="FNV62_RS07605"
                     /old_locus_tag="FNV62_07750"
     CDS             7269..7946
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433207.1"
                     /locus_tag="FNV62_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07750"
                     /product="AIM24 family protein"
                     /protein_id="WP_060897522.1"
                     /transl_table=11
                     /translation="MKGDLFSSDHMVQPAVTPGMTIQNAKSIKYAVNGDMLARQGAMIA
                     YRGNLQFERKGQGVGGMLKRAVTGEGLPLMTVRGQGEAWFAHEAQNCFIIGIEPGDLFT
                     VNGRNVLCFDSTLSYEIKTVKGAGVTGGGIFNSVFSGHGSLGLICEGNPLVIPVSPQQP
                     VYVDTDAVVGWTAQLHTSLHRSQSIGSMIRGGSGEAVQLKLEGDGLVVVRPSEATPQKA
                     QQH"
     gene            complement(8024..9799)
                     /locus_tag="FNV62_RS07610"
                     /old_locus_tag="FNV62_07755"
     CDS             complement(8024..9799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982566.1"
                     /locus_tag="FNV62_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07755"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_144314895.1"
                     /transl_table=11
                     /translation="MRRPHIRRVAIAVAVTTAATLPMAPAFAAPDSPARAATSASSPVE
                     AARAAAFAHASATGVGPGDTLRATDVMTDPDGKQHVRFVRSHQGLPVLGGDLVVHLGKQ
                     SAYLGVTRAADHAVKPATTEAKLTPQQAEQKAAAVAQGDAGSAELVVDARDGAAALAYQ
                     VRVTDSDTTEAGGSRTVVVDAQSGRIRSNTPDSDEFISPHLEETLREKGETASPVTGVA
                     TQPAGLLGATTAARYPVTATGSGTSLFAGKVTLTTTRTARTSFLLKDPTRWNTETRDAK
                     GAELEAFSRGTKFTSTTNKWGTGTTANRTTAAVDAQYGITQTLDFYKKTFGRKGIKNNS
                     TGARAMVHLGRKVGNAFWDSTCGCMLYGDGDGAMFKKPLVVLDVTGHELTHGVVDATAA
                     LEPTRVDARGNQYGEPGALNESLADIFGSNVEFSANNPKNPPNYLMGEKLGLAQKFLRR
                     LDHPSLDKLEGTIDYWSPAAYDTEVHAGSGVSSHAYYLLAEGSGRKTIGGVKYDSPTFD
                     GSRVTGIGRAKATAIFYRALTRYMVSTTDFHDARTATLEAAADMYGATSAEYQAVDAAW
                     AAVNVTTANTPAVGR"
     misc_feature    complement(9943..9958)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(10001..11056)
                     /locus_tag="FNV62_RS07615"
                     /old_locus_tag="FNV62_07760"
     CDS             complement(10001..11056)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670760.1"
                     /locus_tag="FNV62_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07760"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_144314897.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.4e-63, bitscore:
                     213.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPRTVLTAPPAAPEILARCRELVAPALAEAVDGLHPWVAEMAG
                     YALGRCEVGGAPATHRQGKGVRQALAVLGAEAAGGSAEAGVPGAVAVELLHTFSLLHDD
                     IMDGDALRRGRPAVWKAYGTGPAVLTGDALFALAVETLTAAPATSHAAAAVRRLTKASR
                     DLVRGQADDLLFAHRPWTGPDAVSAGEYEAMAEHKTGALLGCALALGAGLAGAPRETAA
                     ALDRAGRHLGVAFQIADDLLGIWGDPAVTGKPVHGDLRQGKKTLPVLAALAAPDRSPLA
                     ELLASTAVLDDGAVRRAATLVERAGGRTAALGAARRHLTAADTLLAGASLAPRPAADLR
                     TLLSSLAHRTI"
     gene            complement(11053..12111)
                     /locus_tag="FNV62_RS07620"
                     /old_locus_tag="FNV62_07765"
     CDS             complement(11053..12111)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982568.1"
                     /locus_tag="FNV62_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07765"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_144314899.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYQGALTTLSVNSSLTDVLAAGTEQLRAAERVGARAE
                     AARSGLAVAEAHRRLGQVADADRAWKASYRTAREARDTGAMAWALWSGGTLARQRGAFP
                     LAWRLLRLAAELGEQSGDVVVRGYSLAGMAETGRIQGDYAAVTALHEQLLAEARRRGEA
                     RHTVWALEGIAQIHRNTGAYDTAYALFEEAAEIAARAEDRRGHAWALRGLADIVSVRDR
                     DPDRALALLSEAEVSCRAMNLSGALAYNHKMRGNVLYRAGRYERARDLYTRALAEFEAM
                     SEPRGRALSRLGLVKSLARLGRDHADTAAELTELARVLEGIGLRHAQEMVERARTELGL
                     TPPEGADPEAAR"
     cand_cluster    11558..21944
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    11558..21944
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[16557:16944](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      16558..16944
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            12417..13301
                     /locus_tag="FNV62_RS07625"
                     /old_locus_tag="FNV62_07770"
     CDS             12417..13301
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018892332.1"
                     /locus_tag="FNV62_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07770"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_144316432.1"
                     /sec_met_domain="APH (E-value: 1.1e-29, bitscore: 103.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPGEFPIDASLVRRLLAAQFPRWAELPLKRFPSAGTVNALYRLG
                     DDLAVRLPRIEGGAEDVAREAHWVPRLAPLLPAAVPEILATGTPGEGYPWPWMVQRWLD
                     GEPPRAGRLSDPLPLAADLGAFVAALRRVRLPDGPTAYRGVPLSTADAMTRAALDELRG
                     TIDTSAATAAWEAALAAPAWTGPPTWAHSDLMPGNLLTRGDRLDAVLDFGTVGVGDPAC
                     DLIPAWNLLPAEARDTFRRAAGADDAAWARGRGWALSMALIQLPCYRVTNPVIAANAEH
                     VIHAVLTEADARP"
     misc_feature    complement(13310..13324)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(13310..13325)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(13311..13324)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.35"
                     /tool="antismash"
     gene            13346..13972
                     /locus_tag="FNV62_RS07630"
                     /old_locus_tag="FNV62_07775"
     CDS             13346..13972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526757.1"
                     /locus_tag="FNV62_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07775"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_144314901.1"
                     /transl_table=11
                     /translation="MSTHLQGSLFDQTDELHLSQLNATRRTVLGDGAWIDLLPGWLSGA
                     DALFARLVEEVPWRAERRQMYEHVVDVPRLLAYYRASDAPPHPILDEARQALSAHYARE
                     LGEPFTTAGLCYYRDGRDSVAWHGDRIGRGAREDTMVAILSVGAPRDLLLRPRRGGETV
                     RRPLGHGDLIVMGGSCQRTWEHAIPKTARAAGPRISVQFRPDGVN"
     gene            complement(14012..14611)
                     /locus_tag="FNV62_RS07635"
                     /old_locus_tag="FNV62_07780"
     CDS             complement(14012..14611)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138616.1"
                     /locus_tag="FNV62_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07780"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_143607190.1"
                     /transl_table=11
                     /translation="MSTVSTPPPGLSASPIAPPRRDAEATKATILRAARHLMARHAHAD
                     ITLKAIADRAGVSAPLILKYFGNKDALFGRVMSFETDAAALLDAPLDQLGPHMVRQVLV
                     GQTERGADPVLRIIFAPRQGDQGDVMRANFRTQVSDRLALRLSGPDADLRAELAVGTLL
                     GLGAMYGIARGTRLRATAIEDIVDRYGPTVQALLTP"
     gene            complement(14608..16053)
                     /locus_tag="FNV62_RS07640"
                     /old_locus_tag="FNV62_07785"
     CDS             complement(14608..16053)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670769.1"
                     /locus_tag="FNV62_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07785"
                     /product="MFS transporter"
                     /protein_id="WP_143607191.1"
                     /transl_table=11
                     /translation="MVALRDRLTVPVLALGGSLMAVMQVVVVPLLPDLPRLTGASAGAV
                     SWMVTATLLTGAVLNPVLGRAGDMYGKKKVLLIALGMMTVGSLMCALTSDIRILIAARA
                     LQGAAAAVVPLSISLLRDELPPERTGSAVALMSSTVGIGAALGLPIAAIVVQYASWHVM
                     FWGTTAVGALGTALAWWAVRESPVREPGRFDMTGALGLALGLSCLLLGVSQGGQWGWSS
                     PRILGLFVGSVCVLGLWWAQQLRAARPLVDLKLATSPRVALPHVAALLTGFAFYANSLV
                     TAQLVQAPKATGYGLELSIVATGLVLLPGGVIMLLLSPVSARISAARGARVTLALGTLV
                     IAAGYGIRIINSHSLLVILLGSAVCAMGTAFSYSALPTLILRAVPAGQTASANGVNVLM
                     RTVGQAVSSAAVAAILVHHTSLVGGAPIPTLHGYLLAFAMAGTVALVACVAALVIPADP
                     TLRDTRRASGSSDAPRDEAFEGA"
     gene            16558..16944
                     /locus_tag="FNV62_RS07645"
                     /old_locus_tag="FNV62_07790"
     CDS             16558..16944
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038019.1"
                     /locus_tag="FNV62_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07790"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_054236852.1"
                     /sec_met_domain="melC (E-value: 4.3e-47, bitscore: 159.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELTRRRALGAAAALAAAAGTQTVAVARAADTGHHVGPEAFDEV
                     YRGRRITGRAAGGGHHHEHGAGYAVFVDGVELHVMQNADGSWISVVSHYDPVPTPRAAA
                     RAAVVELQGAPLVPLGMPMPMPQQ"
     gene            16979..17803
                     /locus_tag="FNV62_RS07650"
                     /old_locus_tag="FNV62_07795"
     CDS             16979..17803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982575.1"
                     /locus_tag="FNV62_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07795"
                     /product="tyrosinase family protein"
                     /protein_id="WP_143607192.1"
                     /transl_table=11
                     /translation="MTVRKNQANLTADEKRRFTDALLQLKRSGRYDAFVTTHNAFILGD
                     TDNGERTGHRSPSFLPWHRRFLLEFERALQSVDASVALPYWDWSTDRSPRSTLWAPDFL
                     GGTGRSLDGRVMDGPFAASAGNWPISVRVDGRTYLRRSLGSGTRELPTRAEVDSVLGMA
                     TYDMAPWNSSSDGFRNHLEGWRGVNLHNRVHVWVGGQMATGVSPNDPVFWLHHAYIDKL
                     WADWQRRHPASGYLPLSGTPDVVDLDETMKPWNDVKPAELLDHTAFYTFDTV"
     gene            complement(17877..18083)
                     /locus_tag="FNV62_RS07655"
                     /old_locus_tag="FNV62_07800"
     CDS             complement(17877..18083)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07800"
                     /product="hypothetical protein"
                     /protein_id="WP_144314903.1"
                     /transl_table=11
                     /translation="MLAAAGLPGSPALEAMQEALYQVGAWWPLEDAVVLTERPVVLLHQ
                     DGTDTTAPHVRIGYADGWQVEDV"
     gene            complement(18191..19471)
                     /locus_tag="FNV62_RS07660"
                     /old_locus_tag="FNV62_07805"
     CDS             complement(18191..19471)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058533.1"
                     /locus_tag="FNV62_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07805"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_144314904.1"
                     /transl_table=11
                     /translation="MSDRGLEARQFGHRARLALSPALALKADDQAHAARTMWNLLHVWW
                     QMMPKEKRTLANADAAIRQARQDIDFLAVLPAQAAQAVLKTYFQAWKNCWDGRADTPNF
                     KGRFRTVMSVDIPQGRDLNITRVHRRWGTVNIPKVGRVRFRWTKDLPVGKRAGAENRIT
                     GARLSRDALGWHIAFRVQTLEVRPDPHQGPDVGVDVGVTVPIALSDGETYEHGEWLTGK
                     EKARLLHLEQRAAQRRRHRNPGERTSRRLRRTYDQIAELRAKAKRRALDWQHQTTTVIA
                     RTYGTVVVEALTITNMVKSAKGTIEEPGKHVAQKAGLNRSISGEAWGRTVTMLTYKLAQ
                     LGGTLHKVPAPGTSRRCSVCGFTMPGNRESQAVFVCKNPDCGWSGNADHNAARNVLHLY
                     RMGHALIPAAGRAVARRAPRVKPATAR"
     gene            19497..19927
                     /gene="tnpA"
                     /locus_tag="FNV62_RS07665"
                     /old_locus_tag="FNV62_07810"
                     /pseudo=""
     CDS             19497..19927
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058534.1"
                     /locus_tag="FNV62_RS07665"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07810"
                     /product="IS200/IS605 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSPHWNPNPSARTRRHVLHSLHVHLVFVTRYRRNAFTDTMLTRCE
                     EVMRKVCTNFEAELKQFNAEQDHIHLLVHYPPKVQLSKLVNSLKGVSSRRLRQKYDSHV
                     RKYLRGGHFWSGSYFAAHATEHR"
     gene            complement(20020..20529)
                     /locus_tag="FNV62_RS07670"
                     /old_locus_tag="FNV62_07815"
     CDS             complement(20020..20529)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07815"
                     /product="hypothetical protein"
                     /protein_id="WP_144314906.1"
                     /transl_table=11
                     /translation="MDSPLGGAPASWALRHGREDGLDGTLFTDLAAGPPLRLSPEFARR
                     NGCAGNSRRRVSAGCRPVARALTGTFWDTSEARTRLVRALGEPLYDTLGLHWERGESGA
                     YELEEEMSRVLSRSTDPAPGRFGGLVRRRLQDRLRGPVPEHIVRPVRVMDVITPPPPPS
                     REEIYL"
     misc_feature    20643..20657
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    21386..21399
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
ORIGIN
        1 tcactcactc gctcaccagg cgtgcccggg caccgcagac cgcccgacgg acaacacccc
       61 cgcggcaatc ccgcggggca tgggcccggc gggccccgct gctcccggcc ctgatcttca
      121 tgatcgtggt cacccagctg ccgttcgtcg gcaccgtggt gatctcgttc atgcgctgga
      181 acgccctcga tccggacaac aaggccttcg cgggcctcca gaactacaag gaggcggtga
      241 ccgatccgca gctgcgttcc tccctgctga cgactgtcac gctgaccgtc agcgtggtcc
      301 tggtcagcct ggtcctgggg ttggggctgg cgctgttgct ggaccgccag ttccgcggcc
      361 gcggcattgt ccgcacgatg ctgatcacac cgttcctcgt cgtgcccgtg gcctccgcgc
      421 tgctgtggaa gcacgcgctg tacaacgcca cctacgggct gatcaacgga tcgctcacct
      481 ggctgtggag cctgttcggc agcgacagcc caccgcagcc cgactggctg tcgtcgctac
      541 cgctgatgtc cgtggaggcg tcgctgatct ggcagtggac gcccttcatg atgctgatcc
      601 tgctggccgg actgcagagc cgccccatgg acgccgtcga ggcggcccgc gtggacggcg
      661 ccaccacctg gcaggtcttc cgctacctca ccttccccca cctgcgccgc tacctggaac
      721 tcgccgcact gctcggcagc atctacgtgg tgcagaactt cgacgccgtc ttcaccctca
      781 ccggcggcgg cctcggcacc gccaacctgc cctacgcggt ctacgagacc ttctaccagg
      841 cccatgacta cggccaggcc tccgcggagg gcgtcatcgt cgtcctgtgc tcccttctcg
      901 tgggctcctt cgcgcttcgg accgtctcat ccctgctccg agaggagact cgctgatggc
      961 cgcgaccctc gacactcccc agcgccccag gggctttgcg gcccgaggcc gacgcggtgc
     1021 gctcggcctg ctggcctggc tctgcggaac cgtgttcttc cttccggtcg cctggatggt
     1081 gctcacctcg ctgcaccgcg agtccgacgc cgcgaccaat ccgccgagcc tgggggcacc
     1141 gctgaccctc cagggctatc gggagttctt cggcgcgagt accggagtct ccccctggcc
     1201 gcccctcatc aactccttct ccgcaagcct catgtcgacg ctgctggtgc tggtgctgtc
     1261 catcccggcc gcctacgcac tgtccatcaa accggtgcgc aagtggaccg acgtgatgtt
     1321 cttcttcctg tccaccaaga tgctgcccgt ggtggccggc ctgctgccga tctacctgat
     1381 cgcccagaac agcggcatgc tcgacaacgt cgcgctgctg gtcgtcctct acacctcgat
     1441 gaacctgccg atcgcggtgt ggatgatgcg ttccttcctc gccgaggtcc ccgtcgagat
     1501 cctggaggcg gcctccatcg acggcgccgg actgcccacc gtcctcgccc ggatcgtcgc
     1561 accggtcgtc gcgcccggca tcgctgccac ctcgctgatc tgcttcatct tcagctggaa
     1621 cgaactcctc ttcgcacgcg tgctcaccgg cgtcgtcgcc ggcaccgcac ccgtgttcct
     1681 caccggcttc gtcaccagcc agggcctctt cctggccaag gtgtgcgccg ccgccgtctg
     1741 catctccctg ccggttctca tcgccggatt cgccgcccag gacaagctgg tccagggcct
     1801 gtcccttgga gcagtcaagt gaaagccgcc gtcatcagct cgcccggcca ggtcggcgtg
     1861 gagaccgtcg acgaccccac accgggcccc ggccaggtgg tgatcgaagt ctcggcctgc
     1921 ggcctgtgcg gcaccgatct ccacatactc cagggcgagt tcgcacccac cctgcccatc
     1981 atccccggac acgagttcgc cggcgaggtc gtcgccctgg gctccggggt acgcgacctg
     2041 aaagtcggcg accgcgtcgc cgtagacccc tccctgtact gccacgagtg ccactactgc
     2101 cgtatcgggc gcggcaacat gtgcgagcgc tggaacgcca tcggtgtcac cgtccccggc
     2161 ggcgccgcac agtacacggc cgcccccgcc gccaactgcg tcaagctccc cgagcacgtc
     2221 cgcaccgagg acgccgccct catcgaaccg ctgtcctgcg cggtgcgcgg ctacgacatc
     2281 ctgcgctcca cgctcgccag caatgtgctg atctacggct cgggcaccat gggcctgatg
     2341 atgctggaac tcgccaagcg caccggcgcg gccacggtcg acatggtcga catcaacgag
     2401 gaccggctcg ccaccgcccg caccctcggc tgcagcaacg cggtgaccac cgccgacgcg
     2461 atcgagcgcc cgcgcggctg ggacgtcgtc atcgacgcca ccggcaacgc ccacgccatc
     2521 caggacgccc tgagccgggt cggcaagggc ggcacctacc tccagttcgg cgtcgccgac
     2581 tacgcgaccc gggccaccat cgacccgtac cgcatctaca accaggagat caccatcacc
     2641 ggctcgatgg cggtcctgca cagctacgag cgcgccgcag aactgttcgc cggcggcgtg
     2701 ctcgacccgg agatcttcat cagtgaccgg ctgccgctgg cggactacgc cgaggccgta
     2761 cggcagttcc aggccggcaa ggcccggaag atccaggtcc tcccgtgacc gggagactcc
     2821 cgccactcgt catcggcgaa gccctggtgg acatcatcgc cggccccgac ggcccgcgcc
     2881 gcagccaccc cggcggcagc cccgccaacg tggcgctggg cctgggccgg ctcggccacc
     2941 cggtccggct cgccacccgc gtgggaaacg acccccacgg tcgcctggtg cgagagcacc
     3001 tggagggcag cggggtcgaa ctggcaccgg gctccgtggt cggcatcgcg acctccacag
     3061 caacggccgt actcgacgac acgagcgccg cgaactacgc cttcgacctc acctgggcac
     3121 tgccagcggc cgtcgaggag tcgctgcgcg acggcccgcc ggcgcacgtc cacaccggat
     3181 ccatcgccac tgccctggct ccgggagccg accaggtcct cagcgccctg cacggcctac
     3241 gggcctcggc aaccgtctcc tacgacccca acctgaggcc cgcgctgctc cgctccgggg
     3301 agcgggaacg cgaacgggtg gaacaactcg tcgccctcag cgacgtggtg aaggcgagcg
     3361 aggaggacct ggcctggctc cacccggacg tcgaccccga caggacggcg gctcgctggg
     3421 cccgaaacgg cccggcattg gtcgtcctca ccctgggagc agacggcgcc cgggcctggt
     3481 ggcgacacgg ctgccaggac atcgcaccgt tgcccgtccg ggtcacggac accgtggggg
     3541 cgggcgacgc ttcatggccg gactgaccag cgggctactc cacgccgggc tgctgggagg
     3601 cggcgccgaa gccgaggcgg cgacggcacg cgcggcactc cgcgcggcga cggagaccga
     3661 ccgactgccc acggccctcg ccgcggcgct ggcagtggcc gcccgagcgg ccgctcttac
     3721 atgcgcgcgc gagggggcga acccgcccgc tgcagcagaa ctgatggtgt gaccttcggg
     3781 ccgtccgtcc cgttccggcg cggcgggctg ctcgggcgtg gcagcacgac accggatcac
     3841 tgcagccacc gcctgccatg tcgctcgtgc cgacggcacc gtcgacaagc ggggccggct
     3901 gctgttgcac cccgaccacg agggcggccg ggacgcccgg cacacagcgc tgcgctcggg
     3961 gcagcccgcg ctgctggccc acatccgccg gctcccactt gagcactacc gatggtgctc
     4021 gtgcggcgtc gcggtgccct gcgcatcgct tccttcgagg aagagctcgg cggccagggc
     4081 gcccggggcg accgcgggcc gccgcacata cccggccggc gcaaacaggg acgcaagggc
     4141 ccctggctca tccggagcgt cggcagatcc caaaggaacg cctactgcca cgagtacacc
     4201 ctttgactaa gggagtacga gcggcgctgg ggagcacatg aggagagtcg actgcgtaac
     4261 tccatgcacc ttgaaagaca ctcaaagact catcgacgca ggcaatggac tgcgatgatc
     4321 gcttcggcgc aggtcagggc tacctgataa atcgcttccg ccggctgccg gtcagatccg
     4381 ccccggacat caccgtgtaa cgccacccca ggcccagttg gaccagacca atcctgtccg
     4441 aatcgttgac atgtacggca cccgccgcaa ttctgagagc gctctcaacg agaaccggac
     4501 ggctccactc cgccggaatc cacctcgttg gaatcccccc actcaaggag agagcgagtg
     4561 cccagaaggc tcaggagtct caaatggcat gccctggcgg tggctgcggc caccgccacc
     4621 acggcgcttc tcacgttcgg cgccccctcc gacgcgaacg cggccgtccc ggcgacgatc
     4681 ccactcaagt tcaccaacaa ctccggccgc agcgaacccg tgtacatcta cgacctcgga
     4741 acgctcctct cgacgggcca gcagggctgg gccgacgcga acggcacgtt ccacgcctgg
     4801 ccggccggcg gcaatccgcc gacgcccgcg cccgacgcct cgatcgcggg accggccaac
     4861 ggccagtcga tgacgatccg gatgcccaag ttctccggcc ggatctactt ctcctacggc
     4921 cagaaactcg acttccgcct gaccaccggc ggcctggtgc agccggccgt gcagaacccg
     4981 agcgacccca accacaacat cctcttcaac tggtccgagt acacgctcaa cgactccgga
     5041 ctgtggatca acagcaccca ggtcgacatg ttctcggccc cgtacgccgt cggggtccag
     5101 ctcgccgacg ggagcaccaa gaacaccggc cacctcaagg cgggcggcta caccgggttc
     5161 ttcaacgccc tgcgcggcca gcccggcggc tgggccaatc tgatccagac ccggtccgac
     5221 ggcaccgtcc tgcgggcgct ggctcccggc cacggcatcg aggcgggcgc gctgccgggc
     5281 accgtcatgg acgactacgt caaccgcgtg tggcagaagt acagttcgtc gacgctgacc
     5341 gtgacaccgt tcaccgatca gccgaacacg aagtacttcg ggcgggtctc cggtgacgtc
     5401 atgaacttca ccaacagcgc cggagccgtc gtcaccagct tccagaagcc cgactcggac
     5461 agcatcttcg gttgctacaa gcggctggac gccccgaacg acctggtacg cggccccatt
     5521 tcacggaccc tgtgcgcggg cttcaaccgc tcgacccttc tcaccaaccc caaccagccg
     5581 gacacgagct cggcgagctt ctaccaggac acggtgacca accagtacgc ccgcaagatc
     5641 cacgcgcaga tggccgacgg caaggcctac gcgttcgcct tcgacgacgt gggcaactac
     5701 gagtccctcg tccacgacgg caacccccag caggcgtacg tcacgctgga cccgttcaac
     5761 tgacggaaac cgaagggcta gggcctgtcc ggcaccgggc aggtggtccg cttcacgagg
     5821 tcgtgccagc cggactccag gcgttcgagc ggcatcccgc actgtcgcgt caggtggtgg
     5881 atcagggcgg gttccaggta gcccatgagg gtctgggcga ggagaacgcc gtccgcgccg
     5941 ggcacggcct cgcgcagcag catgacgacg tgggtgaagc ggacccggta aggggcggag
     6001 ctgaagcggc gggaggcgtc cggctcggcg gcgaggtaca ggtcgagccg gtcgtggatc
     6061 tcgcgcagga cccggcagcc gaaggcgtgc aggcggtccg ccggggccgc gccggggccg
     6121 agaggtggcg ggccgctgag gaaggcggcc tggaactgct gctcggtgtg gtcgagcagg
     6181 gccatcagca ggccggtgcg gtcaccgaag cgccggaaga cggttccctt gcccaccgag
     6241 gccgcggcgg cgacggcctc catcgtcaca ttggcgaccc cgtgctcctc caccagccgg
     6301 gtggcggcct ccagcagccg ggcgcggttg cgcgcggcat cggcgcggag ctgcggcgcg
     6361 gcgggcccga cggtcagctc cagcgggacc ggggctcccg agggttcctg ccccctcggg
     6421 aagggcggaa gtggggtgga catgaacaca gcgtaacggc agaagggggc aactggaccc
     6481 tggtccgttt aggtgctaca acattaaaca gaccagcaag cggacctcgg tccgttttat
     6541 tgccgcaatg tttcgtcccc gggagttccc atgtccgtac gcatcctcgc gctcgtcggc
     6601 agccttcgcg ccggctccca caaccgccag ctcgcggagg cggccatcaa gctcgccccc
     6661 gagggcgcgg agatcgagct gttcgaggga ctcgccgagg tccccttcta caacgaggac
     6721 ctcgacgtcg agggcaaggt cccggccgcc gccaccgccc tgcgtgaggc cgcgggccgt
     6781 gccgacgcct tcctgctctt ctcgccggag tacaacggca cgatcacggc cgtcctgaag
     6841 aacgccatcg actggctgtc gcgtccgtac ggcgccagcg ccttcaccgg caagcccgcc
     6901 gccgtggtcg gcaccgcgtt cggtcagttc ggtggcgtct gggcgcagga cgaggcccgc
     6961 aaggccctgg gcatcgcggg tgccgccgtc ctggaggacc tcaagctctc cgttcccggc
     7021 tccgtgaccc gcttcgccga gacccacccg gtcgacgacg ccgaggtcgc cgcccagctc
     7081 accgaggtcg tcgcccgcct gcacagccag gtcggcaccg ccagcgcctc ctgacgactc
     7141 cccccagggc cggtccggtg ccaccggacc ggcccttcgc gcgttcccgg cagccgccga
     7201 ccacccccaa ccgtccccgg atgtcggcga tcttggcgga accaaaccct ccgggccaag
     7261 atgcccgcat gaagggtgat ctcttttcca gtgaccacat ggtgcagccc gccgtcacgc
     7321 cgggcatgac catccagaac gccaagtcga tcaagtacgc cgtcaacggc gacatgctcg
     7381 cgcgccaggg ggcgatgatc gcctaccggg ggaatctgca gttcgagcgc aagggccagg
     7441 gcgtgggcgg catgctcaag cgggcggtca ccggtgaggg actgccgctg atgacggtgc
     7501 gcgggcaggg cgaggcctgg ttcgcgcacg aggcgcagaa ctgtttcatc atcggcatcg
     7561 agccgggcga cctgttcacc gtgaacgggc gcaacgtcct gtgcttcgac tccacgctgt
     7621 cgtacgagat aaagaccgtg aagggcgcgg gcgtcaccgg cggcggcatc ttcaacagcg
     7681 tcttcagcgg tcacggcagt ctggggctga tctgcgaggg caacccgctg gtgatacccg
     7741 tctcgccgca gcagccggtg tacgtcgaca cggacgcggt cgtcggctgg accgcgcagc
     7801 tccacacctc gctgcaccgc tcgcagtcga tcggttcgat gatccgcggc ggctcgggcg
     7861 aggccgtgca gctgaagctg gagggggacg gactggtcgt cgtacggccg agtgaggcga
     7921 ctccgcagaa ggcacagcag cactgacgcc gaggggaaac ggcgaaaggg gccccgccag
     7981 tggcggggcc cctcttctcg tgccgtcctt ctcgtgccgt ccgtcagcgg ccgacggccg
     8041 gggtgttggc ggtggtcaca ttgacggcgg cccacgccgc gtccaccgcc tggtactcgg
     8101 cgctggtcgc cccgtacatg tcggcggcgg cctcgagggt cgcggtccgc gcgtcgtgga
     8161 agtcggtcgt ggagaccatg tagcgggtga gcgcgcggta gaagatcgcg gtcgccttgg
     8221 cgcgtccgat gccggtcacc cgcgagccgt cgaacgtcgg cgagtcgtac ttcaccccgc
     8281 cgatcgtctt gcggccactg ccctcggcga gcaggtagta cgcgtgcgag gagacgccgg
     8341 agccggcgtg cacctcggtg tcgtacgccg cgggcgacca gtagtcgatg gtgccctcca
     8401 gcttgtccag ggaggggtgg tcgaggcggc gcaggaactt ctgggcgagg cccagcttct
     8461 cgcccatgag gtagttcggc gggttcttcg ggttgttggc ggagaactcg acgttggacc
     8521 cgaagatgtc ggcgagggac tcgttgagcg cgcccggctc gccgtactgg ttgccgcgcg
     8581 cgtccacccg ggtgggttcg agggcggcgg tggcgtcgac gacgccgtgg gtcagctcgt
     8641 ggccggtgac gtccaggacg accagcggct tcttgaacat ggcgccgtca ccgtcgccgt
     8701 agagcatgca gccgcacgtc gagtcccaga aggcgttgcc caccttgcgg ccgaggtgga
     8761 ccatcgcgcg ggcgccggtg ctgttgttct tgatgccctt gcggccgaag gtcttcttgt
     8821 agaagtccag cgtctgggtg atgccgtact gggcgtcgac cgcggcggtg gtccggttgg
     8881 cggtggtgcc cgtgccccac ttgttggtgg tgctggtgaa cttcgtgccg cgcgagaagg
     8941 cctccagttc cgcgcccttc gcgtcccggg tctcggtgtt ccagcgggtg gggtccttga
     9001 ggaggaagct ggtccgcgcg gtccgggtcg tggtcagcgt caccttgccg gcaaagaggg
     9061 aggtgccgct gccggtggcc gtgaccgggt agcgggcggc cgtcgtcgcg ccgaggaggc
     9121 cggcgggctg ggtggccacg cccgtcaccg ggctcgccgt ctcgcccttc tcgcgcagcg
     9181 tctcctccag gtgcggcgag atgaactcgt cgctgtcggg ggtgttgctg cggatccggc
     9241 cgctctgcgc gtccacgacg accgtgcggg agccaccggc ctcggtggtg tcgctgtcgg
     9301 tcacccgcac ctggtaggcg agggcggcgg cgccgtcgcg ggcgtcgacg acgagttcgg
     9361 cgctgcccgc gtcgccctgg gcgaccgcgg cggccttctg ttcggcctgc tggggcgtca
     9421 gcttcgcctc ggtcgtggcc ggcttgacgg cgtggtcggc ggcccgggtc acgcccaggt
     9481 aggcggactg cttgccgagg tggacgacga ggtcgccacc gaggaccggg agcccttggt
     9541 ggctgcggac gaagcggacg tgctgcttgc cgtccgggtc cgtcatgacg tccgtggccc
     9601 gcagggtgtc acccgggccg acaccggtgg ccgaggcgtg ggcgaacgcg gcggcccggg
     9661 cggcctccac cggcgaggag gccgaagtcg cggcgcgggc gggcgagtcg ggcgccgcga
     9721 aggcgggggc catcggaagc gtggccgccg tcgtcaccgc gacggcgatc gccacgcggc
     9781 gtatgtgggg tctacgcact gagttccttc gaacgggggc ggccggcgtc gccaaccgcc
     9841 ctgagacacg gcgccgttga acgccgtgga ggctgtcggg ccctcccgac agatgcgacg
     9901 ggaggggcgg tggttgcccg atgaggtcca ccaacccgca catgtgatcg aggtcgcagc
     9961 gcctccggcc cacagcgggg gagccggagg cacgcaggtg tcagatcgtg cggtgggcga
    10021 gggaggagag gagcgtccgc aggtccgcgg cgggacgtgg ggccagggag gctcccgcca
    10081 gcagggtgtc cgccgcggtg agatgccggc gcgccgcgcc cagggccgcc gtgcgaccac
    10141 cggcgcgctc gaccagggtc gccgcccggc gtacggcgcc gtcgtcgagg acggcggtgg
    10201 aggcgaggag ttcggcgagc ggggagcggt ccggcgcggc cagggcggcg agaacgggga
    10261 gggtcttctt cccttgccgc agatcaccgt gcaccggctt cccggtgacg gccggatcgc
    10321 cccagatgcc gagcaggtcg tcggcgatct ggaaggccac cccgagatgc cgtccggcgc
    10381 ggtcgagggc ggcggcggtc tcccgcggcg cgcccgccag ccccgcaccg agggccagcg
    10441 cgcagccgag cagggcaccg gtcttgtgct ccgccatcgc ctcgtactcc cccgcgctca
    10501 ccgcgtcggg gccggtccac gggcggtggg cgaacagcag gtcgtcggcc tgaccccgga
    10561 ccaggtcgcg cgaggccttc gtcaaccgcc gcacggccgc cgcggcgtgg gaggtcgcgg
    10621 gcgccgcggt gagggtctcg acggccaggg cgaagagcgc gtcgcccgtg aggacggcgg
    10681 ggccggtgcc gtacgccttc cacacggcgg gacggccgcg gcgcagcgcg tcgccgtcca
    10741 tgatgtcgtc gtgcaggagc gagaaggtgt gcagcagttc caccgccacc gcgcccggca
    10801 cgcccgcctc ggcggaaccg ccggccgcct cggccccgag tacggcgagt gcctgtcgta
    10861 cgcccttgcc ctggcggtgg gtcgcggggg ctccgccgac ctcgcagcgg cccagcgcgt
    10921 agccggccat ctccgccacc caggggtgca gtccgtcgac cgcctccgcg agggccgggg
    10981 cgaccagttc gcggcagcgc gccaggatct ccggggcggc gggcggcgcc gtcaggaccg
    11041 tacggggaga ggtcatcggg cggcctccgg gtccgcgccc tccggcgggg tgaggccgag
    11101 ttccgtccgc gcccgttcga ccatctcctg ggcgtgtcgc agcccgattc cctccaacac
    11161 gcgggccagt tcggtgagtt cggcggcggt gtcggcgtgg tcacggccga gcctggccag
    11221 ggacttgacc agtccgagcc gggacagcgc ccggccgcgc ggctcgctca tcgcctcgaa
    11281 ctccgccagt gcccgcgtgt agaggtcccg cgcccgctca taacgcccgg cccggtagag
    11341 gacgttgccg cgcatcttgt ggttgtaggc gagtgccccg gacaggttca tcgcccggca
    11401 ggacacctcc gcctcactca gcagtgccag cgcgcggtcc gggtcccggt cgcgtacgga
    11461 gacgatgtcc gcgaggccgc gcaaggccca ggcgtggccg cgccggtcct cggcgcgcgc
    11521 ggcgatctcg gccgcttcct cgaacagggc gtacgcggtg tcgtaggcgc cggtgttgcg
    11581 gtgtatctgc gcgatgccct ccagggccca cacggtgtgg cgggcctcgc cgcgcctgcg
    11641 ggcctcggcc agcagttgtt cgtgcagggc ggtcacggcg gcgtagtcgc cctggatgcg
    11701 gccggtctcc gccatgcccg ccagggagta gccgcgtacg acgacgtccc cggactgctc
    11761 gccgagttcg gcggccagtc gcagcagccg ccaggccagc gggaacgccc cgcgctggcg
    11821 ggccagggtg ccgccgctcc acagcgccca cgccatcgcg ccggtgtccc gggcctcgcg
    11881 ggcggtgcgg tagctcgcct tccacgcccg gtcggcgtcg gccacctgcc cgagcctgcg
    11941 gtgcgcctcg gcgaccgcca ggcccgaccg ggccgcctcg gcacgggcgc ccacgcgctc
    12001 ggcggcgcgc agctgctcgg tacccgccgc caggacatcg gtcagcgagg agttcacgga
    12061 cagggtggtc aaagcgccct ggtactcggg ggcgaaggcc ttgccgtaca tggatccctt
    12121 tcgatcggct gactttcgcg gaccggcggc acccgacgac tcgactccgc acccctcgta
    12181 tacacgccgt atatacacgc gttgtataca cggagcgtat agtgtgctgg atttccactc
    12241 gggaatccct gccgtttcgc ggttgtcgcg ccgcccatcc gttgtcgatc aagacggcga
    12301 cggcgtgcgc caggttgcct gtcgcgaaaa agaagcgcga acctccttca ccccaggcat
    12361 agttgggccg cgtgtcagac agagatccag aagcgcaaac gatccccgag ggcccgatgc
    12421 gtcccggcga gttcccgatc gacgcctcgc tcgtgcgacg gctgctggcc gcgcagttcc
    12481 cacggtgggc cgagctgccc ctgaagcgct tcccgtcggc gggtaccgtc aacgccctgt
    12541 accggctcgg ggacgacctg gccgtacgcc tcccccggat cgaggggggc gccgaggacg
    12601 tggccaggga agcgcactgg gtgccgcggc tcgccccgct gctcccggcc gccgtccccg
    12661 agatcctcgc caccggcaca cccggcgagg gctacccgtg gccctggatg gtgcagcgct
    12721 ggctcgacgg cgaacccccg cgcgccggcc gcctcagcga tccgctgccc ctggccgccg
    12781 acctcggcgc cttcgtggcc gcgctgcgcc gggtccggct gcccgacggg ccgaccgcct
    12841 accggggtgt gcccctgtcc accgccgatg caatgacccg cgccgcgctc gacgagctgc
    12901 gcggcacgat cgacacctcc gccgccaccg ccgcctggga ggcggcgctc gccgcgcccg
    12961 cgtggaccgg tccgcccacc tgggcccact ccgacctgat gcccggcaac ctgctcaccc
    13021 gcggggaccg gctcgacgcc gtgctggact tcggcaccgt cggcgtcggc gacccggcct
    13081 gcgacctcat cccggcctgg aacctgctcc ccgccgaggc gcgggacacc ttccggcggg
    13141 cggcgggcgc cgacgacgcc gcctgggcgc gggggcgcgg ctgggccctg tccatggcgc
    13201 tcatccagct cccgtgctac cgcgtcacca atccggtgat cgccgccaac gccgagcacg
    13261 tcatccacgc ggtcctcacg gaggccgacg ccagaccctg agacatcaat ggaacgtata
    13321 ttcgaatacg gagtacgctg gaggcatgtc cacgcacctc cagggctcgc tgttcgacca
    13381 gaccgacgag ctccacctca gtcagttgaa cgcgacgcgc cggacggtcc tgggcgacgg
    13441 ggcctggatc gacctgttgc ccggatggct cagtggcgcc gacgccctgt tcgcacggct
    13501 cgtcgaggag gtgccgtggc gggcggagcg gcggcagatg tacgagcacg tcgtggacgt
    13561 accgaggctg ctcgcgtact accgggcgag cgacgcgccg ccgcacccga tcctcgacga
    13621 ggcgcggcag gcgctgtccg cgcactacgc ccgcgagctg ggcgaaccgt tcaccaccgc
    13681 gggcctgtgc tactaccggg acggccgcga cagcgtggcc tggcacgggg accggatcgg
    13741 gcggggcgca cgggaggaca ccatggtcgc gatcctctcc gtgggcgctc cgcgcgacct
    13801 gttgctgcgc ccgcgccgcg gcggggagac cgtacggcgc ccactcggac acggcgacct
    13861 gatcgtgatg ggcggctctt gccagcgcac ctgggagcac gccattccca agacggcgcg
    13921 ggcggcgggg ccgcggatca gcgtccagtt ccgcccggac ggcgtgaact gagcgagggg
    13981 cggccgttcc tgtccggcgg cgtccatcgc ctcacggcgt caggagtgcc tggaccgtgg
    14041 ggccgtaccg gtcgacgatg tcctcgatcg cggtcgcgcg cagccgggtg ccgcgcgcga
    14101 tgccgtacat cgcgccgagc ccgagcagtg tgccgacggc gagttcggcg cgcaggtccg
    14161 cgtcggggcc gctcagccgc agggcgaggc ggtcgctgac ctgagtgcgg aagttggcgc
    14221 gcatgacgtc gccctggtcg ccctggcgcg gggcgaagat gatccgcagg acggggtcgg
    14281 ctccgcgctc ggtctggccg acgagcacct ggcggaccat gtgggggccc agttggtcca
    14341 ggggcgcgtc caggagggcg gcggcatccg tctcgaagga catcacgcgc ccgaagagcg
    14401 cgtccttgtt cccgaagtac ttgaggatca gcggagcgct cacccccgcg cggtcggcga
    14461 tcgccttgag cgtgatgtcc gcgtgggcgt gccgggccat cagatgccgg gccgcgcgca
    14521 ggatggtcgc cttcgtggcc tcggcgtcgc ggcgcggtgg ggcgatcggg ctcgcgctga
    14581 ggccgggggg cggagtggac acggtgctca ggctccttcg aatgcctcgt cccgaggtgc
    14641 gtccgagctg ccggaggccc gtcgggtgtc acggagggtg gggtcggcgg gtatgacgag
    14701 ggcggcgaca caggccacca gtgcgaccgt acccgccatg gcgaaggcca gcagatagcc
    14761 gtgcagcgtg gggatcgggg cgccgccgac gaggctggtg tggtggacca ggatggcggc
    14821 gacggcggca ctgctcacgg cctggccgac ggtgcgcatc agcacgttga cgccgttcgc
    14881 ggacgcggtc tgccccgcgg gcaccgcgcg caggatgagg gtgggcagcg ccgagtagga
    14941 gaacgccgtt cccatcgcgc agaccgcgga acccagcagg atcaccagca ggctgtggct
    15001 gttgatgatg cgtatgccgt agccggcggc gatgaccagg gtgcccagcg ccagcgtcac
    15061 ccgggcgccg cgggccgccg agatacgcgc cgagaccggc gagagcagca gcatgatcac
    15121 cccgccgggc agcaggacca gacccgtcgc cacgatggac agctcgaggc cgtagccggt
    15181 cgccttgggc gcctgcacca gctgcgccgt caccagggag ttggcgtaga aggcgaagcc
    15241 ggtcagaagc gccgcgacat ggggcagggc gacgcggggg ctggtcgcca gtttcaggtc
    15301 gaccagaggg cgcgcggcgc gcagttgctg cgcccaccac aggccgagga cgcagacgct
    15361 cccgacgaac aggccgagga tccgggggct gctccagccc cactggccgc cctgcgacac
    15421 ccccagcagc agacaggaga gccccagggc caggcccagc gcgccggtca tgtcgaagcg
    15481 gcccggctcg cggacgggcg actcgcgcac cgcccaccag gccagcgccg tcccgagggc
    15541 gccgaccgcg gtcgtccccc agaacatgac gtgccagctg gcgtactgaa ccacgatcgc
    15601 ggcgatcggg aggccgaggg cggcgccgat cccgacggtg gagctcatca gcgccaccgc
    15661 ggaacccgtg cgctcgggcg gcagttcgtc ccgcaggagg ctgatcgaca acggtacgac
    15721 ggcggccgcg gccccttgca gggcccgggc cgcgatgagt atgcggatgt cggacgtgag
    15781 ggcgcacatg agcgagccga ccgtcatcat cccgagggcg atcagcagca ccttcttctt
    15841 gccgtacatg tcgccggcgc ggccgagtac ggggttgagc accgctccgg tcagcagcgt
    15901 cgccgtcacc atccaggaca cggcgcccgc cgacgcgccc gtcagccgcg gcaggtcggg
    15961 cagcagcggc accaccacca cctgcatgac ggccatgagg ctcccgccga gcgcgaggac
    16021 cgggaccgtc agtcggtcac gcagtgccac catgaactct ccagaagtcg gcgcgaagaa
    16081 ggggggtgaa tagcaattca ccatagccgg tgaattgcta ttcacccaat gggcgcccta
    16141 ctttcgggcg gcgctctgca ccgacagcgg cgccgttcgc gtggctccag gtgcactccc
    16201 gcacagcgag tggtcgcgga cggcgcgtgc ggagtcggga tcggcctcaa ttgaccacgt
    16261 agagcggcag accggcgcga cccccgtggt tcgcgccagc ttgggggcgt gagccgcgcc
    16321 acccgccatc ggccgccccg ggaagatcat cggcggaacg tcggccgacc ggaggaattc
    16381 caccttccgg tcgatcgcgg atgcccgcac agcaagatca tcttcgttca accttgcacg
    16441 acatttactt aattgtcctg atcacggcca accgacatcc ggcgatttct cccgctctcc
    16501 gacgaaccga taggcatatc gggtcatcga ccgagcttga tcgcaggagg tctccgcatg
    16561 ccggaactca cccgtcgccg tgccctcggg gccgcggccg ccctcgccgc cgcggccggc
    16621 acccagaccg tcgccgtggc cagggccgcg gacaccggac accacgtcgg gcccgaggcc
    16681 ttcgacgagg tgtaccgggg tcgtcgcatc acgggccgcg ccgccggcgg tggtcaccat
    16741 cacgaacacg gcgccgggta cgccgtgttc gtcgacgggg tcgagctgca cgtgatgcag
    16801 aacgccgacg gcagctggat cagcgtcgtc agccactacg acccggtgcc caccccgcgc
    16861 gccgccgccc gcgccgcggt cgtggaactc cagggggcac cgctcgtccc cctcggcatg
    16921 cccatgccca tgcctcagca gtgacccagc cccgtcagca caccgtggag tcccgcacat
    16981 gaccgtacgc aagaaccagg cgaacctgac cgccgacgag aagcggcgtt tcaccgacgc
    17041 gctcctccag ctgaagcgca gtggccggta cgacgccttc gtcaccacgc acaacgcgtt
    17101 catcctcggc gacacggaca acggcgaacg gacgggccat cgttcgccct ccttcctgcc
    17161 ctggcaccgc agattcctgc tggagttcga gcgggcactg cagtccgtgg acgcctccgt
    17221 cgccctcccg tactgggact ggagcaccga ccgttcgccc cgttccaccc tgtgggcccc
    17281 cgacttcctc ggcggcaccg gacgcagcct ggacgggcgg gtgatggacg gccccttcgc
    17341 ggcctccgcg ggcaactggc cgatcagcgt gcgcgtcgac ggccgtacgt atctgcggcg
    17401 ctcgctcggc agcggtaccc gtgagctgcc gacccgcgcc gaggtggact ccgtgctcgg
    17461 catggcgacg tacgacatgg cgccctggaa cagttcctcg gacggtttcc gcaatcacct
    17521 cgaagggtgg cgaggcgtca atctccacaa ccgggtgcac gtctgggtcg gcggccagat
    17581 ggccaccggt gtctccccca acgaccccgt cttctggctg caccacgcct acatagacaa
    17641 gctctgggcc gactggcagc gccgccaccc cgcctccggc tatctgccgc tctccggcac
    17701 ccccgacgtc gtggacctcg acgagaccat gaagccgtgg aacgacgtga aaccggcgga
    17761 gctgctggat cacaccgcgt tctacacctt cgacaccgtc tgaccgcgcg ttcgcaggtc
    17821 cagccccggt cgccgctcct caccgggagg ggagagcggg gccccacgcc gctcgtctag
    17881 acgtcctcca cctgccagcc gtccgcgtac ccgatccgta cgtgcggcgc ggtggtgtcc
    17941 gtgccgtcct ggtgcaacag gacgacgggg cgctcggtga ggacgacggc gtcctccagc
    18001 ggccaccagg cgcccacctg gtacaaggcc tcctgcatgg cctccagggc gggcgagccg
    18061 ggcagcccgg cggcggcgag catgcagcgc cagtggatca actcccctgc ggcggaccag
    18121 ctgtccagcc tgccgccgaa ctcctgccgg aattgaagtg ctctcccagc taaagcaggg
    18181 agattcccgc ctaccttgcg gtggcgggct tgacgcgcgg tgcgcgcctg gcgactgccc
    18241 tcccggcagc cgggatgagc gcgtggccca tccggtacag gtgcaagacg ttccgggccg
    18301 cgttgtggtc ggcgttaccc gaccagccgc agtccgggtt cttacacacg aacacggcct
    18361 ggctctcccg gttgccgggc atggtgaagc cgcacactga gcagcgcctg gaggtgccgg
    18421 gggcaggaac cttgtgcagg gtgccgccga gctgggcgag cttgtacgtc agcatggtga
    18481 ccgtccggcc ccatgcctcc ccgctgatgg agcggttcag cccagccttc tgggcaacgt
    18541 gcttccccgg ctcctcgatg gttcccttgg cggacttgac catgttcgtg atggtgagtg
    18601 cttcgaccac gacggtgccg tatgtgcggg cgatgacggt ggtcgtctgg tgctgccagt
    18661 ccaaagcccg gcgcttggct ttcgcgcgga gttctgcgat ctggtcgtag gtgcggcgta
    18721 gccggcggct ggtgcgctcg cctgggttgc ggtgccgcct acgctgcgcg gcgcgctgct
    18781 ccaggtgcag aagcctggct ttctccttgc cggtcagcca ttcgccgtgc tcgtacgttt
    18841 caccgtccga gagggctatg ggcacggtga cgcccacgtc gacgccgacg tccggcccct
    18901 ggtggggatc gggcctgacc tccaaggtct ggactcggaa ggcgatgtgc cagccgagcg
    18961 cgtccctgct cagtcgtgca ccggtgatcc ggttctccgc gcctgcacgc ttgccgaccg
    19021 gaaggtcttt ggtccagcgg aagcggaccc ggcctacctt gggaatgttg accgtgcccc
    19081 agcggcggtg cacgcgggtg atgttcaggt cgcggccctg cgggatgtcc acggacatca
    19141 ccgtgcggaa ccggcccttg aagttcgggg tgtcggcgcg gccgtcccag cagttcttcc
    19201 acgcctggaa gtacgtcttg agtaccgctt gcgcggcctg ggcggggagg acggcgagga
    19261 agtcgatgtc ctggcgggcc tggcggatcg cggcgtccgc gttcgccagg gtccgcttct
    19321 ccttcggcat catctgccac cagacgtgca ggagattcca catcgtgcgg gccgcgtgcg
    19381 cctgatcgtc agccttgagc gccagggcag gggacagtgc aagccgggcg cggtgcccga
    19441 actgccgtgc ctccaggccg cgatcactca cggacgacac cctacggtat tggtttatgt
    19501 caccacactg gaatccaaac cccagcgcgc gcacccgccg tcacgtcctg cacagcctgc
    19561 acgtccactt ggttttcgtc accaggtacc ggcggaacgc gttcaccgac accatgctga
    19621 cccgctgcga ggaggtcatg cgcaaggtct gcaccaactt cgaggccgag ctgaagcagt
    19681 tcaacgcaga acaggaccac atccacctcc tcgtgcacta cccgcccaag gtgcagctct
    19741 ccaagctggt caacagcctc aagggcgtct catcccgacg cctgcgccag aagtacgaca
    19801 gccacgtccg caagtatctg cggggcgggc acttctggtc tggctcctac ttcgcggctc
    19861 atgcgacgga gcaccgctga ccgccgtacg ccagtacatc gacaaccagc agcgccccac
    19921 gaactgacgc agacagcaca gacccatgct cacacgcgac tcagagcagt tctgagacgg
    19981 ccttcacccc cgccgtaaac ggcggagcac tggccaagat cagaggtaga tctcctcccg
    20041 gctcggcggc ggtggcgggg tgatgacgtc catgacacgg acgggccgaa cgatgtgctc
    20101 cggcaccgga ccgcggagcc tgtcctgaag gcggcgccgc accagcccgc cgaagcgccc
    20161 cggcgcgggg tccgtcgacc gggaaaggac acggctcatc tcctcctcca gttcgtaggc
    20221 gccggactcg ccgcgttccc agtgcaggcc gagcgtgtcg tagaggggct cgcccagggc
    20281 ccgtaccagt cgtgtcctcg cttcggaggt gtcccagaag gtgccggtca acgctcgcgc
    20341 gaccggccgg cagccggccg acacccgccg ccgggagttg cccgcgcatc cgttcctccg
    20401 cgcgaactcc ggcgagagcc gcagcggcgg accggcggcg aggtcggtga acagcgtccc
    20461 gtcgagcccg tcctcgcgcc cgtggcgcag tgcccaggac gccggtgcgc cgcccagcgg
    20521 ggagtccatc cacacgacgg tccgcgggac cggcagacca tgggcgcggt acacggcggc
    20581 gaccgaggcc tcggccctcg gccggtcgca gggctaggta ctcagccccg cccgcagcca
    20641 tcggtcggct tcggccagca cgcgggcctc gacgtccgcg gtcagtagtt cttcgtgccc
    20701 catttcgtcc ccatccccca tcccccatct ttcatcgcct atccccccat cccccatctc
    20761 ccacccgaat ccgtcgctac cgtgtcaccg cgtgcagata gccgtcctcg ctgccgacgt
    20821 acaccacgcc gtcggacacg gcgggcgtgg agtacacggc cccgccggtg gcgaacttcc
    20881 accgctgttt gccggtcggg ccgttcaccg cgtacaggtg ccggtcgcca ccgccgacgt
    20941 acaccacccc gtcggagacg gtcggcgagg agagcgtgcg tttgccgatg ggaaacttcc
    21001 atcgtcgctt gccggtggcg gcctccaccg cgtacaggtt gccgtcggca ctgccggcgt
    21061 agaccacccc gtcggacacg gtcagcgacg aggacacgac acctccgacc gctgtcttcc
    21121 atcgttgatc gcccgtcacc gcgtccaccg cgaggagggt gccgccctcg gagccggcgt
    21181 agaccactcc gtcgaccacg gcgggccgcg tgaacacgct ggcgtcggtg gtggccttcc
    21241 accgctgctc accggtggcc gcgtccaccg cgaacaggct gtggaaactg ccgaagtaga
    21301 ccaccgcctc tgccacggtc ggagacgagg acaccccgcc gccggcgaag aagtgccact
    21361 tttcgctgcc gtcggcgatg tccacggcat gcaggttgcc gttctcaccg ccggcataga
    21421 cgatcccacc gacctcggtg ggcgactggg aaccgacgct gccgaggtgg aacttccact
    21481 gttccttgcc ggtggcgccg tccagtgcgt acaggttctc gtcgacgctg ctgaggagga
    21541 cggtcccccg gacggcgacc ggtgacgaat acccgacacc ggttctgggg cgcttccagc
    21601 gctgttcgcc ggtggaggcg tccaccgcgc acaggttccg gctgctgctg atgtacacca
    21661 gatcgtccac cacggccggc gacgcgtaca ccaggccgcc gacctggaac cgccagcgct
    21721 gctcgccggg cccggcctcg cgccttcggg tggcggagga cctgttgtcg tagatgctcc
    21781 agccgccgaa cccaagaccc gcgacaccgg cgcccatgcc gagcagggcc cgtcggcgcg
    21841 acggccccgc cggcccaccg gcggcatcga cggacggcgg ccggtcgccg tcgggccact
    21901 cccccgtccg gggcggcgcc acccacgccg acggttcggg cgtg
//
