LOCUS       NZ_CP041610            22527 bp    DNA     linear   CON 14-NOV-2023
DEFINITION  Streptomyces sp. RLB3-17 chromosome, complete genome.
ACCESSION   NZ_CP041610
VERSION     NZ_CP041610.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RLB3-17
  ORGANISM  Streptomyces sp. RLB3-17
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/14/2023 04:19:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,027
            CDSs (total)                      :: 10,924
            Genes (coding)                    :: 10,421
            CDSs (with protein)               :: 10,421
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 503
            CDSs (without protein)            :: 503
            Pseudo Genes (ambiguous residues) :: 0 of 503
            Pseudo Genes (frameshifted)       :: 178 of 503
            Pseudo Genes (incomplete)         :: 409 of 503
            Pseudo Genes (internal stop)      :: 52 of 503
            Pseudo Genes (multiple problems)  :: 128 of 503
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1490545
            Orig. end                         :: 1513072
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041610.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041610.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22527
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="8"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22527
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22527
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12527](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12527)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    236..249
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
     gene            327..>1316
                     /locus_tag="FNV62_RS07160"
                     /old_locus_tag="FNV62_07295"
                     /pseudo=""
     CDS             327..>1316
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059348.1"
                     /locus_tag="FNV62_RS07160"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07295"
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNDKEIPAVEPVEDKLVDEVVERLMDRADASGAALLGEGGLLTEV
                     TRAVLERALDAEMTDHLGYEKHDRAGRGSGNSRNGTSPKTVLTDAGTVTLAVPRDRDGS
                     FEPQLVPKHARRLAGFNEQVLSLYARGMSVRDIRSHLAGMYGVEVSPDLISKVTDAVTD
                     ELEAWQNRPLDAVWPIIYIDALWVKIRSGSVASRPVYLAVGVDMDGCKDVLGLWAGDEG
                     EGATTWMTVLSELRNRGVEDVCIVACDGLKGLPDAVTATWPKATVQTCVIHLIRASLRF
                     ASKQHHAKLVAELKAIYTAPTEQAAEQALTDFAAGELGQRYPAIVRTWE"
     gene            complement(1324..3366)
                     /locus_tag="FNV62_RS07165"
                     /old_locus_tag="FNV62_07300"
     CDS             complement(1324..3366)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012464.3"
                     /locus_tag="FNV62_RS07165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07300"
                     /product="recombinase family protein"
                     /protein_id="WP_143600355.1"
                     /transl_table=11
                     /translation="MSGSQKITSSHRSRLALIYVRQSTLLQVRENTESTARQYGLAERA
                     RQLGWAESDITVVDTDLGVSGRFSGLRAGFQQLVARVCLGEVGAVFGLEVSRLARSSAE
                     FGRLLEFARLTDTLLIDGDGVYDLGDFNDRLVLGLKSTMSEAELHILAGRLHGARRAAA
                     ERGDLRLPLPVGLVHDAEGRIVIDPDEEVRAAVADIFTLFDQHGSALGVVRAFSGRRFP
                     RRDTGVWDGRLGWGRLTHGRAAAVLKNPVYAGAYVFGRATSTRRVRPDGTVVNTVNRRP
                     RDQWAVLIPEHHEGYISWQHYLRIEAKLAANRTSTGARPPREGPPLCQGVIFCGSCGFP
                     MNTSYRRADNTPDYVCTRSRSDAVSTPGRHSIAASAVDGQVARLLLAALTPEQVHLALM
                     AADEVHHRHQRSHRAAELAVERARYEADRAERAFSQVEPENRLVARSLESRWEAKLTAL
                     NQAEAALADLIISEPALPEPAQLQQLARDLPTLWEAPTTTAKDHKRLLRTLIADVTVRH
                     VDDTRAHIGIRWHTGATDEITCDRRTNRNPTRAVEIVRELLDTRSDAEIAEHLNTLGFS
                     TGKCRPFTVASVRHIRQQHAIGPKRNDPTGPGEITVPQAARILGIHEATIYPWLRSGEM
                     TARQGRHRRWCIPWNSEVEEYWRTRVATSSHLTRTNPIYETGQAV"
     gene            complement(3506..3760)
                     /locus_tag="FNV62_RS07170"
     CDS             complement(3506..3760)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF036442.3"
                     /locus_tag="FNV62_RS07170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5372 family protein"
                     /protein_id="WP_164331618.1"
                     /transl_table=11
                     /translation="MVTHPFHPWSGRRVRVCRSVRRGGGLVFVCTAGDGMTVTLPQAWT
                     DRVPVPGENRLAADGLGALSALVNALMSRCGEPGGGGPS"
     misc_feature    complement(3766..3780)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.19"
                     /tool="antismash"
     gene            <3810..4097
                     /locus_tag="FNV62_RS07175"
                     /old_locus_tag="FNV62_07305"
                     /pseudo=""
     CDS             <3810..4097
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014059348.1"
                     /locus_tag="FNV62_RS07175"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07305"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="WQAAWSEFTPYLAFPPEIRKVVYSTNLIESINARLRKATRNRGHF
                     PSEQAALKVLYLAVREQITPRARDVNHVAPHWKKALNQFSLFFENRLNTK"
     gene            4221..5735
                     /locus_tag="FNV62_RS07180"
                     /old_locus_tag="FNV62_07310"
     CDS             4221..5735
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1206: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029007.1"
                     /locus_tag="FNV62_RS07180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07310"
                     /product="ISL3 family transposase"
                     /protein_id="WP_143651897.1"
                     /transl_table=11
                     /translation="MLPQLAAVQVREVQAGGDLIQIMARTRDGVAVACSGCGWLSDWVH
                     SRYERHVADEAVGGRPVTVDLSVRRLYCENPGCSKTTFVEQVDGLTVRYQRRTPALQQL
                     LSAVAAALVGKTAVRLLPHLHQLVSCSTLLTMLMALPLPVLPVPQVLGVDDFALRRGHR
                     YATVLIDVITHARVDVLADRTAETLTAWLRAHPGVEVVCRDGSAGYAEGIRQGAPDAVQ
                     VSDRWHLWHNLAAAVEKTVAAHAACWRAVPPEATPGSRNARVLQTHAAVHASLETGVSL
                     CETGRRLGLALNTVKRYARVGDPAQLIRPPQYRRCLVDPYRDHLRTRRAAGPVATTTLL
                     AEIRVLGYTGSPNLLVRYLEQGRAEESLADPSVRRLTSWIMTDPDHLADEPGTHRDKLT
                     AVCPEMTALTSHVTAFAKLLAHHEHPTTGHAALAEWIEAVNGDDLPALHAFVRGLQKDQ
                     DAVQAGLDLPYSNGATEGINNKTKLLKRQTYGRAGFALLRQRILLN"
     misc_feature    4338..4340
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4578..4580
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6015..6422)
                     /locus_tag="FNV62_RS07185"
                     /old_locus_tag="FNV62_07315"
     CDS             complement(6015..6422)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07315"
                     /product="hypothetical protein"
                     /protein_id="WP_143600356.1"
                     /transl_table=11
                     /translation="MLEALDQEKGLALAETLTEADERIAAGETVSSSAADRYRTAAAEF
                     SHRYAGTYLGKRELRALVANPRLQVYEDPKAFLACNHDAFTALCNPEPRPPPRRRPEHP
                     RPLPLQPGLPQHQPCPGSPDGWRHPGAGDRK"
     gene            complement(6858..7895)
                     /locus_tag="FNV62_RS07190"
                     /old_locus_tag="FNV62_07320"
     CDS             complement(6858..7895)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540636.1"
                     /locus_tag="FNV62_RS07190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07320"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_316738814.1"
                     /sec_met_domain="fabH (E-value: 1.3e-108, bitscore: 362.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFARKAMPPSPAPAARLIGLGSYLPPLKVSNADLAARLDTTDEW
                     IRTRIGIAERHIADPATATSNLAVEAGLRAMKSAELEHVDAVILATATPDHHVPGTAPV
                     VAHQLGLCQVPAFDLGAGCSGFVYATTVAAGLIHAGTVGTVLVIGAEKMSAVIDPADRS
                     TAPIFGDGAGAVVLTAGHADEPGALGPAAWGSDGEHADAIVIPGGGSRSPSRTTADLEN
                     LYVRMKGNEVFRHAVRRITHVTQEAATAAGWAAQDIDRLIVHQANARISAAVANALGIP
                     AERVPSNIARVGNTSAASIPLLLSHAAIDGQLEARQRVVVTSFGAGFTWAATTLLWPIG
                     LQALA"
     gene            complement(8059..9684)
                     /locus_tag="FNV62_RS07195"
                     /old_locus_tag="FNV62_07325"
     CDS             complement(8059..9684)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0045017 - glycerolipid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (446-508). E-value: 8.3e-09.
                     Score: 27.6. Matches aSDomain:
                     nrpspksdomains_FNV62_RS07195_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018657.3"
                     /locus_tag="FNV62_RS07195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07325"
                     /product="wax ester/triacylglycerol synthase family
                     O-acyltransferase"
                     /protein_id="WP_144314863.1"
                     /sec_met_domain="PP-binding (E-value: 2.2e-06, bitscore:
                     27.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPLRPTPMDLTMHDMAQVYPTISQTIGVILHLEGTTPTLSELR
                     AYGGSHLKDQPRLTHYLHGPGLKARWHHDPAPDLNHRVREQHLPSGDQHLDTALTGLVA
                     HPLPAEGPLWDIWLLAGYAPGRYAICLRAHHSTQDGMGLISTLTALFGTAPAPTTHPAL
                     RAGAAAYLSTVRGMLTASAINNAWNDTELSLTGHRDINWADVPTQRLRQAATARGGDTN
                     DGFLAALSGALRTWAAQSWPRGADRPLPAITMVNLRRTEDHDRPGNYFTFAPAPLPCHE
                     PTAEGRLDHVIAATRTTKDPARHKAMRSVMDLVPARAFHALATRLTTPDRATISTSYLA
                     VHRPLHYKQDPVTRLQPFTWLPRHQPASIVACSYNGTTSICFVTDAALPGLNQLPRLFH
                     DAVGDLPRSDDDPQAGSRAEQLPHAGVTLPVPAAACDTAVVIDFDFIKGILVHQGNLPA
                     ESITRQATQEEAGIDSLAVTELSMILEERLGVVITENELAKPTTMDDLVSLVAQRTASS
                     PDRESPQEQGLHPQTERPHAVPEA"
     aSDomain        complement(8161..8346)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV62_RS07195_PP-binding.1"
                     /evalue="8.30E-09"
                     /label="FNV62_RS07195_PP-binding.1"
                     /locus_tag="FNV62_RS07195"
                     /protein_end="508"
                     /protein_start="446"
                     /score="27.6"
                     /tool="antismash"
                     /translation="KGILVHQGNLPAESITRQATQEEAGIDSLAVTELSMILEERLGVV
                     ITENELAKPTTMDDLVS"
     gene            complement(10001..11518)
                     /locus_tag="FNV62_RS07200"
                     /old_locus_tag="FNV62_07330"
     CDS             complement(10001..11518)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012647.3"
                     /locus_tag="FNV62_RS07200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07330"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_164657620.1"
                     /sec_met_domain="T2TS (E-value: 3.5e-47, bitscore: 160.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVLNRVGADGAVRDACRSRVLESALALALVERCGSGHHDAGTRI
                     VSYLERHQNSEDLIDTTVAAAALGRGTRQPARRQALEDIVSRVPDFTGSRKRALVQAIF
                     TMLGVATDHADVAPHAVDVSALHPWAAVQTVAVNAILGRAVGGNRAGGEDVTRLASTQR
                     PGRVWEGNLFIHLSVLHALVDVPGMESVVDAGLSTALRHQREDGGLPFVTDTDTWSTVV
                     VGLALGSAGAPREVMHRIARHLVRVQHANGGWSYTDHAELSDTDCTTVAVEFLHQLDPV
                     AYRDPIERALDALVAVRGADGGFPTYGAGTPSEACMTAAAINALSTQDRHRHLIQPALR
                     FLADRQVPDGSFPPGWSSSRLHTLFRAYLATHHWQASLTVQDMSGRIAGLVQSTQNADG
                     GFGQRDGASSDAISTAYALIILAGQRDPAPAAHATGYLLTQQRPDGSIISVPDMLGPRP
                     FPYHVPVLTDAFTLLALGHLTPRIRPSRIAVPGRQDSNAQLAQRTAP"
     gene            complement(11673..12527)
                     /locus_tag="FNV62_RS07205"
                     /old_locus_tag="FNV62_07335"
     CDS             complement(11673..12527)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.2"
                     /locus_tag="FNV62_RS07205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07335"
                     /product="hypothetical protein"
                     /protein_id="WP_144314867.1"
                     /sec_met_domain="T1TS (E-value: 9.7e-50, bitscore: 169.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVDAFEEGRLLAMRLGKLAELAVPEASDADLELTAQWAAFICLV
                     DDRFDRSRVDIRPEEVASLFTRLLNVITGGPAGSVSGIEQALDDLWRRTAPRMSTQWRE
                     RFVADYRDFALAMQEEAAGRTDRVPMGLSDYVLRRRRTITALPLADILECTAGAPWPGL
                     PMGEDLMRALRRAVADVAGWSNDLVSEEDDLREDRDNLVTVLSRERGCSLSSAREQATA
                     MRDGRVRDFHALAASLAAMTLPGTEREEVRRYVAALGSFVAATLHWLGVTHRFDARWAP
                     RPV"
     gene            complement(12638..13030)
                     /locus_tag="FNV62_RS07210"
                     /old_locus_tag="FNV62_07340"
     CDS             complement(12638..13030)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07340"
                     /product="hypothetical protein"
                     /protein_id="WP_144314869.1"
                     /transl_table=11
                     /translation="MKGKISLDLTEGSWTAGGGLTFTRASDGRSLRFTGAHGDLARRSM
                     LVDATVGDEAALPVDLSTYELDMTKITVTMPSVNSPGSVEGRPFNTTLKPDGAAVFSRA
                     FGASLVPTGSGLATLAGRVDVVPALG"
     gene            13369..13584
                     /locus_tag="FNV62_RS07215"
                     /old_locus_tag="FNV62_07345"
     CDS             13369..13584
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07345"
                     /product="hypothetical protein"
                     /protein_id="WP_144314871.1"
                     /transl_table=11
                     /translation="MATRTPTSVHHIGHLACGFRLNYIQEPANPPGSERTAQKIRRQEQ
                     GHQYAQEQVIALRAPRPRRGCDRPSG"
     gene            14068..14700
                     /locus_tag="FNV62_RS07220"
                     /old_locus_tag="FNV62_07350"
     CDS             14068..14700
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040050.2"
                     /locus_tag="FNV62_RS07220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07350"
                     /product="DUF6302 family protein"
                     /protein_id="WP_143600363.1"
                     /transl_table=11
                     /translation="MTNHRTKREVSENRAAVIAQKATVVRRYTYEGASMAALCRDYGVG
                     IGWLRRQFDSWDVPRRPRGRTAYAAVQETSADDRERAALAQRLAEPGLLEQSLVLDLSS
                     APVSGAGVSPLAVPVGGVRVAGEVTVGNWGEALIVILQLEAHPERYPKVRQRKPLGSPW
                     EPRTICWGTSTPVDDWPTRGRMFGYHEAGINEYTAAHAQSSAPLGQR"
     gene            15282..>15797
                     /locus_tag="FNV62_RS07225"
                     /old_locus_tag="FNV62_07355"
                     /pseudo=""
     CDS             15282..>15797
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: TauD (46-160). E-value: 1.8e-11. Score:
                     36.3. Matches aSDomain:
                     nrpspksdomains_FNV62_RS07225_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014698.3"
                     /locus_tag="FNV62_RS07225"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07355"
                     /product="TauD/TfdA family dioxygenase"
                     /pseudo=""
                     /sec_met_domain="TauD (E-value: 3.2e-09, bitscore: 36.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEYRTELTATPRFEETAATLRHALTGEGGGYAVLCLGNLAKALG
                     TDADRFLRLVTGFAAEVAVPFSPFPRWPLWKDIGVKVDKDPGKSSGIGYNAFHMDLVNG
                     TLPPDYTTLLCVRPDPLGGGPSILSDAHAAVARLSENSRALLAETAYHYGTFFDLHGVG
                     EEYKPFPIL"
     aSDomain        15420..15761
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV62_RS07225_TauD.1"
                     /evalue="1.80E-11"
                     /label="FNV62_RS07225_TauD.1"
                     /locus_tag="FNV62_RS07225"
                     /protein_end="160"
                     /protein_start="46"
                     /score="36.3"
                     /tool="antismash"
                     /translation="DADRFLRLVTGFAAEVAVPFSPFPRWPLWKDIGVKVDKDPGKSSG
                     IGYNAFHMDLVNGTLPPDYTTLLCVRPDPLGGGPSILSDAHAAVARLSENSRALLAETA
                     YHYGTFFDLH"
     gene            complement(15950..17134)
                     /locus_tag="FNV62_RS07230"
                     /old_locus_tag="FNV62_07360"
     CDS             complement(15950..17134)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004993514.1"
                     /locus_tag="FNV62_RS07230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07360"
                     /product="ISAs1 family transposase"
                     /protein_id="WP_143600364.1"
                     /transl_table=11
                     /translation="MPAEASSLIPPALDQLREHPEAAPEEVPGLLGRLAQVPDPRDPRG
                     VRHALVGVLALVACAVLAGATSLLAVGEWITDAPPHVLEHVGVRFDPLFPKRCLPAETT
                     VRRLLARIDGDALDLAVGRWLADRRHRTRGRLRGLAVDGKSLRGAARANGRRIHLLAAL
                     DHTTGLVLAQLDVQEKTNEITCFQPLLEAMADLAGVVVTSDAMHTQCEHADYLLGREAH
                     YIVIVKGNQKKLRKQLRSLPWTEIPLQGRVKGTGHGRSEIRRIKAVTVNSLLFPGARQA
                     VQIKRRRTDRKTGKTTIKTVYAVTSLTAEQAIPAQLATLIRDHWQIEALHHVRDTTFAE
                     DASQLRTGNAPRAMATWRNLAIGALRLAGATSIAAALRHNARNADRPLALLGLK"
     gene            17291..17449
                     /locus_tag="FNV62_RS07235"
                     /old_locus_tag="FNV62_07365"
     CDS             17291..17449
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS07235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_07365"
                     /product="hypothetical protein"
                     /protein_id="WP_143600365.1"
                     /transl_table=11
                     /translation="MLQPGDYLIVNQRRFLHGREALHSGQETVPVTDTRLLLQLFLRAR
                     AGAGSAA"
     gene            complement(17580..18353)
                     /locus_tag="FNV62_RS07240"
                     /old_locus_tag="FNV62_07370"
     CDS             complement(17580..18353)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008412403.1"
                     /locus_tag="FNV62_RS07240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07370"
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_143600366.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-31,
                     bitscore: 108.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLVSVVMPVHNSAATLGASVRSVLAQTHPDVELLVTDDASTDGS
                     MDLLQDLARRDERVRPQAAPEQGGAARARNLALARARGEYVAFLDSDDMWLPGKVERQL
                     AFAADGDAPLTFTSYYKVAGDYTGEACDFTPNGRVVAARERVTYRDMLVQDHIGALTAM
                     YDRTVLGTRLMPDMPKRQDYALWLSIMRDGHPARGLQEPLAVYRAGRAGSLSSNKLALV
                     EHNWRLYREHEHLSVFRSTRALAGATWHSVRKSHI"
     gene            18436..19692
                     /locus_tag="FNV62_RS07245"
                     /old_locus_tag="FNV62_07375"
     CDS             18436..19692
                     /GO_function="GO:0003979 - UDP-glucose 6-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152: nucleotide sugar dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380150.1"
                     /locus_tag="FNV62_RS07245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07375"
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="WP_143605229.1"
                     /transl_table=11
                     /translation="MKVIIAGQGYVGLPLAVRAAEVGHRVVGYDVDLHRIEQLTAGESY
                     VEDVASSRLRAVLDTGAYSATADAAALAGFDIAVITVPTPLRDGVPDLTYVESCARTLG
                     EHLRPGATVVLESTTYPGTTEELLLPILEKTSGLKGGVDFLAGFSPERIAPGNKRWSFD
                     GTPKLVSGIDARSLDAIKGFYDAIFQTTVPVSGTRVAELAKLIENIFRFVNISMANEMA
                     MLAASLGVNIWEAIDAAATKPFGFTRFTPGPGVGGHCLPVDPLFLSWKVQQELGAPFRF
                     VELADDVNRHMPDYVVRRLTEALDKRRMTISESRILLLGLTYKYNATDLRNSPSARVAE
                     LLINLGAEVRGADPNIPDGDDTKLNVPWVDASPEEVAAADAVVLLMDHTRFDLAMIEKN
                     APYVLDCRNRLSGPNVETL"
     gene            complement(20019..21407)
                     /locus_tag="FNV62_RS07250"
                     /old_locus_tag="FNV62_07380"
     CDS             complement(20019..21407)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_040423240.1"
                     /locus_tag="FNV62_RS07250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_07380"
                     /product="IS1380 family transposase"
                     /protein_id="WP_144314448.1"
                     /transl_table=11
                     /translation="MQSSHAAAAVSSAFDDPNLIAYGGLEPVVRLAERCGLPALVGEYI
                     RLPASKDGTGAFPAAKVMSLVGGMVAGADSIDDMHRLRHGAMGRLFSGVRAPSTLGSFL
                     RSFTHGHVKQLHAVARRFLPELARHAPLLPGADQVAYVDIDDTIRRTYGYAKQGTGYGY
                     SKVKGLNALLGIVSTPLAAPVIAATRLRKGPSNSARGAAAFVAETIRTARACGANGLLV
                     MRADSAFYGADVVNSCRALGARFSITVRMNASVKAAIARIDEDAWMPIKYPKAVWDEEG
                     QCWISDAEIAETGYTAFTSKPKKQQVTARLIVRRVKRLSTGTVPAGQGTLFDTWRYHAA
                     FTDSPLSLNDAERDHRRHAVVEQVIADVKNSAFAHAPSGHFQANAAWLALAALAHNLTR
                     AAGALAGTFHARATTATIRDHLINVPARLARSARRLTLHLPERWPWSTDFTQLFSIVHA
                     PPAP"
ORIGIN
        1 ggcccggcca tcctgaacgg acaccgcgcc gtcggccaac tcctcgtcgt ggacccgcgc
       61 ctcgacgtcc gacgagaccc cgtcctgctc ggcgaagagg tcaaagacgg gtgcgccgtc
      121 ctcgcaccgc tggcaagcgg cccggcgctg ctcgccaccg ccatcgcacc caccacctcg
      181 acactgcgga aactgctcga cgaggcatac gcacacgcgt tcgcccgtta atggatggag
      241 cgtgtctgaa agatcgtgta agtccgtgat gtgacaggct ggtcggggct ctgaccaggg
      301 tctttgacca gccgggacgg acggacatga acgacaagga gatcccggcc gtcgaaccgg
      361 tcgaggacaa gctcgtggat gaggtcgtcg agcggctgat ggaccgcgcc gacgcctcgg
      421 gtgctgccct gctgggtgag ggcgggctgc tcacggaggt gacccgggcc gtgctggagc
      481 gggccctgga cgcggagatg accgaccacc tcggctacga gaagcacgat cgggcgggcc
      541 gcggctcggg caacagccgc aacggcacat cgcccaagac ggtgctgacc gatgccggga
      601 cggtcacgct ggccgttccg agggaccgtg acgggtcctt cgaaccgcag ctggtgccca
      661 agcacgccag gcggcttgca ggcttcaacg agcaggtcct gtcgctgtac gcacgcggca
      721 tgtcggtgcg cgacatccgc tcgcacctgg ccggcatgta cggcgtcgag gtctcaccgg
      781 acctgatcag caaggtcacc gacgccgtca ccgacgagct ggaggcgtgg cagaacagac
      841 cgttggacgc ggtctggccg atcatctaca tcgacgcgct gtgggtgaag atccgctccg
      901 gatccgtggc ctcccggccg gtttacctgg ccgtcggggt ggacatggac ggctgcaagg
      961 acgtgctcgg cctgtgggcc ggcgacgagg gcgaaggcgc caccacctgg atgaccgtgc
     1021 tgtccgagct ccgcaaccgc ggcgtcgagg acgtctgcat cgtcgcctgc gacggactga
     1081 agggcctacc cgacgccgtc accgcgacct ggcccaaagc caccgttcag acatgtgtga
     1141 tccacttgat ccgtgcctcg ctgaggttcg cctccaaaca gcaccacgca aagctggttg
     1201 cggagttgaa ggccatctac accgccccga ccgagcaggc cgccgagcag gccctcaccg
     1261 acttcgccgc aggcgagctg ggccagcggt accccgcgat cgtgcggacc tgggaagtcg
     1321 gcttcatact gcctgtcctg tctcgtagat ggggtttgtg cgcgtgaggt gcgaggaggt
     1381 cgcgacgcgg gtgcgccagt actcctcgac ctcgctgttc catgggatgc accagcgccg
     1441 gtggcgtccc tggcgggcgg tcatctcgcc actgcggagc cagggataga tcgtggcctc
     1501 gtggatgccg aggatgcgtg cggcctgtgg caccgtgatc tcgccggggc ctgtggggtc
     1561 gttgcgtttg gggccgatcg cgtgctgctg acggatgtgc cggaccgagg cgacggtgaa
     1621 gggacggcac ttgccggtgc tgaagccgag tgtgttgagg tgctcagcga tctcggcatc
     1681 gctgcgggtg tccaggagtt cacggacgat ctcgacagcc cgggtgggat tgcggttggt
     1741 ccgccggtcg caggtgatct cgtcagtggc gccggtgtgc cagcggatgc cgatgtgggc
     1801 tcgggtgtcg tcgacatgtc gcacggtcac gtccgcgatc agggtcctca gcagacgctt
     1861 gtggtccttg gccgtggtgg tcggcgcttc ccacaatgtg ggcagatcgc gggcgagttg
     1921 ttgcagttgt gcgggctcgg gcagggccgg ctcggaaatg atcaggtcgg cgagtgcggc
     1981 ctcggcttgg ttcagggccg tgagcttggc ctcccagcgg gactcgagcg agcgggcgac
     2041 cagccggttc tccggctcga cctggctgaa cgcacgctcg gcgcggtcgg cttcgtagcg
     2101 ggcgcgttcg acggcgagct cggccgcccg gtgcgagcgc tggtgtcggt ggtggacctc
     2161 gtcggctgcc atcagagcca ggtggacctg ctcgggagtc agcgcggcca gcagcagtcg
     2221 ggccacctgc ccgtcgacgg ccgaggcggc gatcgagtgg cggcccgggg tgctgaccgc
     2281 gtcgctgcgt gagcgggtgc agacgtagtc cggggtgttg tccgcgcgcc ggtagctggt
     2341 gttcatgggg aagccgcacg aaccgcagaa gatgacgccc tgacacagcg gcgggccctc
     2401 gcgcggcggt cgtgccccgg tgctggtgcg gttcgcggcc agtttcgcct cgatccgcag
     2461 gtagtgctgc caggagatat agccctcgtg gtgttcaggg atcagaacgg cccactgatc
     2521 gcgaggacgc cggttgaccg tgttgaccac ggtgccgtcg ggccgcaccc ggcgcgtgct
     2581 tgtcgcgcgg ccgaagacgt acgcacctgc atagacaggg ttcttcagta cggcagcagc
     2641 ccgtccgtgc gtgagccggc cccagcccag gcgtccgtcc cacaccccgg tgtcccggcg
     2701 cgggaagcgg cggcccgaga aagcgcggac cactccgagt gcggaaccat gctggtcgaa
     2761 cagcgtgaag atgtcggcga ccgcggcccg gacctcctcg tccgggtcga tgacaatgcg
     2821 gccctctgcg tcgtggacca gtccgaccgg cagcggcagc cgcaggtcgc cgcgttcggc
     2881 cgcggcccgg cgggcgccgt gcagacgccc ggccaggatg tgcagttcgg cctcgctcat
     2941 cgtggacttc agccccagca ccagcctgtc gttgaaatcg cccaggtcat agacgccgtc
     3001 gccgtcgatc aggagggtgt cggtcaggcg cgcgaactcc agcagccgac cgaactcggc
     3061 cgacgaacgc gccagtcggg acacctccag accgaagacc gcaccgacct ccccgaggca
     3121 cacccgggcc accagctgct ggaatccggc ccgcagtccg gagaaccggc ccgagacccc
     3181 cagatccgtg tcgacaaccg tgatgtccga ctcggcccag cccagctgcc gggcccgctc
     3241 ggccagtccg tactgccggg ccgtcgactc ggtgttctcc cgcacctgca gcagcgtcga
     3301 ctgcctcaca tagatcaacg cgagccgaga ccggtgcgag gaggtgatct tctgggagcc
     3361 gctcatgctc accggcctcc ccacgcaggg ccgactcgac catgttcgcg atcaacagcg
     3421 tggcagtacg gtcccagccc tcgacacctg gcaccgtccg tcacccccaa ctgggcaccc
     3481 gccggcacca cgcgtgggct gcccctcacg acggtcctcc gccgcccggc tcgccgcaac
     3541 ggctcatcag ggcattcacc agcgcagaca gcgcgccgag cccgtcagcg gcgagccggt
     3601 tctcacccgg aaccgggacg cgatccgtcc acgcctgcgg cagcgtcacc gtcatcccgt
     3661 caccggccgt gcacacgaag acgagcccgc ccccgcgacg caccgaccga cacacccgca
     3721 cccggcgccc cgaccacggg tggaacggat gggtgaccat cagcgaatct gcagaaacat
     3781 cacgaacagg ggcactgtgc tgtgtcctct ggcaggccgc gtggagcgaa ttcaccccct
     3841 acctcgcctt cccgccggag ataaggaagg tcgtctactc gacgaatctg atcgagtcga
     3901 tcaacgcacg gctgcggaag gccacccgca accgcggaca cttcccctcc gagcaggccg
     3961 cgttgaaggt gctctacctc gccgtccgcg agcagatcac ccccagagcg cgcgacgtca
     4021 accacgtcgc gccacactgg aagaaggcac tgaaccagtt ctcactgttc ttcgagaacc
     4081 ggctcaacac caagtgaaag tcgaggactt acacaaagtt tcgggctctg acttgatttt
     4141 cgtagcgggt gatcgaaccc gtcgtggttc tccctgccct gggcgcagac tggtgggtgt
     4201 atgccctcga gttggaggtc ctgctgccgc agctggccgc ggtgcaggta cgggaagtgc
     4261 aggctggcgg ggatctgatc cagattatgg cccggacccg ggacggtgtc gcggtggcgt
     4321 gttcgggctg tggctggtta tcggactggg tgcacagccg gtacgaacgg catgtcgctg
     4381 acgaggcggt cgggggccgg ccggtcacgg tcgacctctc ggtccgccgc ctgtactgcg
     4441 agaaccccgg gtgttcgaag accacgttcg tggagcaggt cgatggactg accgtgcgct
     4501 accagcgacg cacccctgcc ctgcagcaac tgctgagtgc tgtcgcggcg gcgctcgtcg
     4561 gcaagaccgc cgtccgatta ctgcctcacc tgcatcaact ggtcagttgc agcacgttgc
     4621 tgaccatgct gatggcactt ccgctccccg tcctgccggt tccgcaggtg ctgggagtcg
     4681 atgatttcgc gctacggcgc ggtcaccgct acgccaccgt cctgatcgac gtgatcaccc
     4741 acgcccgcgt cgacgtactg gccgaccgca ccgccgagac gctgaccgcc tggctgcgtg
     4801 cacaccccgg ggtggaggtc gtatgccggg acggctcggc cggctacgcc gagggcatcc
     4861 gtcagggagc ccccgacgcg gtgcaggtca gcgaccgatg gcacctgtgg cacaacctcg
     4921 ccgccgcggt ggagaagacg gtggccgcgc acgccgcgtg ctggcgcgcg gtgccccccg
     4981 aggcgacgcc cgggtcgcgc aacgcgcgtg tcctgcagac ccatgccgcc gtgcacgcct
     5041 cactcgagac cggggtgagt ctgtgcgaga ccggccgacg cctgggcctc gcgctgaaca
     5101 ccgtcaaacg gtacgcccgc gtcggtgacc ccgcgcagct gatccggccc cctcagtacc
     5161 ggcgctgcct ggtcgatccc taccgcgacc acctgcggac tcgccgcgcg gccggtccgg
     5221 tggccaccac caccctcctc gcggagatcc gcgtactggg ctacaccggc agcccgaacc
     5281 tgctagtccg ctacctcgaa cagggccggg ccgaggagtc tttggccgac ccgtccgtcc
     5341 gccgcctcac ctcctggatc atgaccgacc ccgaccacct ggccgatgag ccggggaccc
     5401 accgcgacaa actcaccgcc gtctgccccg agatgaccgc cttgaccagc cacgtcaccg
     5461 ctttcgccaa gctactggcc caccacgaac atcccaccac cgggcacgcg gccctggccg
     5521 aatggatcga ggccgtgaac ggcgacgacc tccccgccct gcacgccttc gtccgcggcc
     5581 ttcagaagga ccaagacgcc gttcaagccg gtctcgacct gccctacagc aacggagcca
     5641 ccgagggcat caacaacaag accaagctcc tcaagcgcca gacctacgga cgagccggct
     5701 tcgccctcct ccgccagcgc atcctgctca actgatcttc gggtcaacgg gacgatcacc
     5761 cgctacgaaa atcaagtcag agccaagttt cgtacacgcc caatggatgt catggcccac
     5821 gaatgagacg gccgaaagaa gcccaggtcg cagggatcga acaggatatt tcggatgcgg
     5881 gcatacacga gtggccccgc tccctcctta cgctgggcgc acggcctacg gcggcggccg
     5941 tcgactggcg aggtcggaca ctcctgcgtt ggtccacctg ccgttccagg gccgtgttcg
     6001 tctctttgag gcggtcattt tcgatctcca gcacctggat gacgccagcc atcaggtgag
     6061 cctgggcaag gctgatgttg gggcaggccg ggttgcagcg ggagtggtcg ggggtgctct
     6121 ggccggcgcc gcgggggcgg ccgcggttcc gggttgcaca gtgcggtgaa ggcgtcgtgg
     6181 ttgcaggcca ggaaggcctt cgggtcttcg taaacctgga gtcgggggtt ggcgaccagc
     6241 gcgcgcagct cgcgtttgcc gaggtaggtc ccggcgtagc gatgggagaa ctcggcggcc
     6301 gcagtgcggt agcggtcggc ggctgagctg ctgaccgttt caccggccgc gatgcgctcg
     6361 tcggcctcgg tgagcgtctc ggccagggcc aggcctttct cctggtccag ggcctcaagc
     6421 atgtcggcct tggagcggcc tcatggtgga gtcgcgtatt ggaactcccc gaatgcctcg
     6481 gccaagggca cagcgaagcg gggcgccggt agccgacgaa gcgcctcgac caggttggcc
     6541 gtcctcaggt acgggcacag actgaccggt tgtctgatcg gcgaactcgc gcgcttccga
     6601 ccgtgcgatg tccaaggtcc gcaacagcga gcgcggccgc ggcggggtgg agcggcgcct
     6661 ggtcaccctc ggtgctcgcc ctcgtggcgc gggcgagccg ggccgggcgt ggctggcgga
     6721 ggccctgcac gacgtcggcg cgcgggacgt gcgccacggc ggccaccacc gcttctgcag
     6781 acagttggcg cgtgctgccg cctggttggc gacgctacca gagcaacgaa cccgtcactg
     6841 gtgagtgcaa taggcgctca ggcgagagcc tggaggccaa tgggccacag cagagtggtg
     6901 gccgcccagg tgaagcctgc gccgaaggag gtcacgacga ctcgttgcct ggcttccagc
     6961 tgcccgtcga tcgcggcgtg acttagcagc agggggatcg aagctgcaga agtattgccg
     7021 actcgggcga tgttggacgg tacgcgttcg gccggaattc ccagggcgtt ggccactgct
     7081 gcgctgatgc gtgcgtttgc ttggtggacg atcagcctgt caatgtcctg ggcggcccat
     7141 cctgctgcgg tggctgcctc ttgagtcacg tgagtgatgc ggcgcaccgc gtgacggaat
     7201 acctcgtttc ctttcatgcg tacgtagaga ttctccaggt cggcagtggt acgtgagggg
     7261 ctccgggacc cgccgccggg gatgacgatg gcgtctgcgt gctcgccgtc gctgccccat
     7321 gcggctggtc cgagggctcc gggttcgtcg gcgtgtccgg ctgtgagtac gactgcaccc
     7381 gccccgtcgc cgaagatcgg cgcggtggat cggtcggcgg ggtcgatgac ggccgacatc
     7441 ttctccgctc cgatgaccag tacggtgccg acggttcccg cgtggatgag tcccgctgcg
     7501 acagtcgttg cgtagacgaa gcccgagcat cctgcaccga ggtcgaaggc aggcacttgg
     7561 cacaggccga gttggtgggc caccaccggt gcggtgccag gaacgtgatg gtccggagtg
     7621 gcggtggcca ggatgacggc gtcgacgtgc tcgagctccg ccgatttcat tgcccggagt
     7681 cctgcctcca cggccaggtt actggtggca gtcgccggat cggcgatgtg tcgctcggca
     7741 ataccgatac gggtgcggat ccattcatct gtcgtgtcca ggcgtgctgc aaggtcggcg
     7801 ttgctcactt tcagtggggg cagataggac cccaggccga tcaaccgcgc ggcaggcgct
     7861 ggcgacggag gcatggcttt acgtgcaaag atcaacggtt tgtcttctct gtgcttgctc
     7921 gttggcgtca ccgtcagcgg aggggatgcc ttcggaattg cggactgacc ggctgctcgt
     7981 tgtgatcccg ctgtcgctgg cgtgctgccg ctgcggccgg tgatgaccgg cgctgttgac
     8041 tggggagccg gggcgcgcct acgcctcggg cactgcgtgt ggtcgttctg tctgggggtg
     8101 gagaccctgc tcttgcggac tctcgcggtc gggggatgat gctgtccgtt gagctacgag
     8161 gctgaccagg tcgtccatgg tggtcggctt cgccagctcg ttttcggtga tcacgacgcc
     8221 taggcgctct tcgagaatca tggacagctc ggtcaccgcc agggagtcga tgccggcttc
     8281 ctcctgcgtc gcctggcgcg tgattgattc ggccggcagg ttcccctggt ggaccaggat
     8341 gcctttgatg aagtcaaaat cgatgacgac tgcggtatca caggcagcgg caggtacggg
     8401 gagcgttacg ccggcgtggg gaagttgctc cgctcggctg cccgcctgcg ggtcgtcgtc
     8461 agagcgcggg aggtcgccca cggcgtcgtg gaacagacgg ggcagctggt tcaggccggg
     8521 gagggcggcg tcggtgacga agcagatgct ggtggttccg ttgtagctgc aggccacgat
     8581 cgatgccggc tggtgccggg ggagccaggt gaagggctgg aggcgggtga cggggtcctg
     8641 tttgtagtgc aacggccggt ggacggcgag gtaggacgtg ctgatggtgg cccggtcggg
     8701 tgtggtcagc cgggttgcca gagcatggaa ggcgcgtgcg gggacgaggt ccatcacgga
     8761 gcgcatggcc ttgtggcggg ccgggtcttt cgtggtgcgg gtggcggcga tgacgtggtc
     8821 gaggcggcct tcggctgtcg gctcgtggca gggcaggggc gcgggtgcga aggtgaagta
     8881 gtttcccggc cggtcgtggt cctcggtccg gcgcaggttg accatcgtga tcgctgggag
     8941 cggcctgtcg gcgccgcggg gccaggattg tgctgcccat gtgcgcaggg ctccgctgag
     9001 ggcggccagg aagccgtcgt tcgtgtcgcc gccgcgggcg gtggcggctt gccgcagccg
     9061 ctgggtgggg acatccgccc agttgatatc gcggtggccg gtcagggaca gttcggtgtc
     9121 gttccaggcg ttgttgatgg cgcttgcggt gagcatgccg cgcacggtgc tcaggtaggc
     9181 cgcggcgcct gcccggagcg ctgggtgcgt ggtgggcgcg ggtgcggtgc cgaacagagc
     9241 ggtcagggta ctgatcaggc ccataccgtc ctgggtgctg tggtgcgctc gcaggcagat
     9301 ggcataacgc cccggggcgt acccggccag cagccagatg tcccacagcg ggccctcggc
     9361 gggcaagggg tgcgcgacga gaccggtcag ggctgtatcg aggtgctggt cgcctgatgg
     9421 gaggtgctgt tcgcggacgc ggtggttaag gtcgggggct gggtcgtggt gccagcgggc
     9481 tttgagtccg gggccgtgga ggtagtgggt caggcgcggt tggtctttca ggtgggagcc
     9541 gccataggcg cggagttcgc tgagggttgg agtggttcct tccaggtgga ggatcactcc
     9601 gatggtctgg gagatcgtgg gatagacctg ggccatgtcg tgcatggtca ggtccatggg
     9661 cgtgggacgc aggggcacgg tcacggggtt ctccgcggtg gtggttcggt ggggggacag
     9721 aggtcaggtc aggccggtgt gagccggaga atcggctgga agtgtcccga gcgttgggcg
     9781 aaggagacgt aggttggccc ggcttggatg aggtggtccc gggcggcggt ccgctcggtc
     9841 ccttccagac ggtcggcagc ggctcggtcg agattggtcg gggacttgtc gcatccgtgc
     9901 acgtggctcc cggctacggg caggggccag tcgatgcccg ctgcacatcc cgtggccagg
     9961 catacgtgcc cgggcgggga agccggtttg gagcgcggac tcatggggct gtcctctggg
    10021 cgagttgcgc attgctgtcc tggcggcccg gcacggcaat gcgtgatggc cggatacgag
    10081 gggtgaggtg gcccagggcg agaagagtga acgcgtcggt caatacgggg acgtgatacg
    10141 ggaaaggacg cgggccgagc atgtcgggaa cggagatgat gctgccgtcg ggacgctgct
    10201 gcgtgagcag gtagccagtg gcgtgcgcag cgggagcagg gtcgcgctgt ccggccagga
    10261 tgatcagggc gtaggcggtg ctgatggcat cgcttgaggc gccgtccctc tgtccgaagc
    10321 cgccgtccgc gttctgtgtg ctctgcacca gaccggcgat ccgaccgctc atgtcctgga
    10381 cagtcagaga ggcctgccag tggtgggtgg cgaggtaggc cctgaagagg gtgtgcaggc
    10441 gactgctgct ccagccgggg ggaaaggagc cgtcaggcac ctgacggtcg gcgagaaagc
    10501 gcagagcagg ctggatgagg tgacggtggc ggtcttgggt gctgagcgcg ttgatcgcgg
    10561 cggcggtcat gcacgcctcg gagggagtgc ccgctccgta ggtggggaat ccgccgtcgg
    10621 cgccgcggac cgcgaccagt gcgtccaggg cacgctcaat cgggtcgcgg taggcgaccg
    10681 ggtccagctg atgcaagaac tcgactgcga ccgtggtgca gtccgtgtcg gagagctcag
    10741 cgtggtcggt gtacgaccag ccgccgttcg cgtgctgaac acgcacaagg tgccgggcga
    10801 tgcggtgcat cacctcacgc ggtgcgccgg cactgcccag agccagaccc acgacgacgg
    10861 tgctccacgt gtcggtgtcc gtgacgaagg gcaggccgcc gtcctcccgc tgatgcctga
    10921 gggcagtact caggccggca tcgacgacgc tctccatacc ggggacgtcc accagggcat
    10981 gcaggactga caggtgaatg aagaggtttc cctcccacac ccttcccgga cgttgggtgg
    11041 atgccagccg agtgacatcc tccccgccag cgcgatttcc acctaccgcc cggcccagga
    11101 tcgcgttcac cgcaacggtc tgcaccgcag cccagggatg cagcgcgctc acatcgacag
    11161 catggggagc gacgtcggca tggtcggtag ccacgcccag catggtgaag atggcctgca
    11221 ccagggctcg tttgcgtgat ccggtgaagt ccggtacccg gctgacaatg tcctcgaggg
    11281 cctggcgacg cgccggctgc ctggtgcccc ggcccagggc agcggcggct acggtcgtat
    11341 caataaggtc ttcgctgttc tgatggcgct ccaggtagct cacgatgcga gtacccgcgt
    11401 cgtggtggcc agatccacac cgctccacca gcgccagggc gagcgcggat tcgaggaccc
    11461 gactgcggca ggcgtcgcgc acggcaccgt ccgctcccac ccggttcagc acgtgcacca
    11521 aaagacgtct gcgtccggca ggcagcgctg ctgggaagta cgacgacagc caggccgggg
    11581 ggagctgctt ggcggcaggg ggtctcaccg gtaggacagt ccttggatgg cacgagaaac
    11641 acggtcgagc gtgaaggggc gaacgaggtc ggtcacacgg gccggggcgc ccaacgggca
    11701 tcgaagcgat gggtgacgcc aagccagtgc agcgtcgcgg ccacaaagga cccgagtgcc
    11761 gccacgtaac gccgtacttc ctcccgctca gttccgggaa gggtcatcgc cgccagcgaa
    11821 gcggccaggg catggaaatc cctgacacgg ccatcgcgca ttgccgtggc ctgctcgcgt
    11881 gccgaggaca gggagcagcc gcgctcacgg ctcagcaccg tcaccaggtt gtcgcggtcc
    11941 tcccgcaggt catcctcctc cgagaccagg tcattgctcc agccggccac atcagccacg
    12001 gcccgccgca gggccctcat gaggtcctcc cccatgggca ggccgggcca gggcgcgcca
    12061 gcggtgcact ccaggatgtc tgccagaggc agggcggtga tggtcctgcg acgccgcagc
    12121 acgtagtcgc tgagccccat cgggacccgg tcggtgcggc cggcggcctc ttcctgcatg
    12181 gccagggcga agtcgcggta gtcggcaacg aaccgctccc gccactgagt ggacatccgc
    12241 ggagccgtac gccgccacaa atcatccagg gcctgctcaa tcccgctgac ggatccggca
    12301 gggccgccag tgatcacgtt cagcagccgg gtgaacagcg acgcgacctc ttccggccgg
    12361 atatcgaccc ggctgcggtc gaaccggtcg tcgaccaggc agatgaatgc cgcccactgc
    12421 gccgtcagtt ccagatcggc gtcgctcgcc tccggcaccg ccagctcagc gagtttcccc
    12481 agccgcatag caagcagacg cccttcttca aaagcgtcaa ccaccacgct caagtcccgc
    12541 gcccatgcca gcaccgcagc gccggtcttc tcagcccgga cctcacccag cagaccagca
    12601 ctgacaaggc cggcaccagt ctccccccac atccgattca gcccagcgcc ggtaccacat
    12661 cgacacggcc cgccagcgtg gccaggccgc tcccagtggg aaccagcgac gcgccgaacg
    12721 ctcgagagaa caccgccgca ccgtccggct tgagcgtcgt attgaacggc ctgccctcaa
    12781 ccgagcccgg cgagttcacg gagggcatag tgaccgtgat cttcgtcatg tcgagctcgt
    12841 acgtggagag atcaaccggc agcgccgctt catctccgac cgtcgcatcc accagcatcg
    12901 accgccgcgc caagtcaccg tgcgccccgg tgaagcgcag actgcgcccg tccgaggccc
    12961 tggtgaaggt caggccacca cccgccgtcc aagacccctc ggtcaggtcg agactgatct
    13021 tgcccttcat cggccactgc acgcacgggg tcggtcctga agagtccagc acagccggag
    13081 caccagccgc catcacaact ccgtcagccg ccagatgctc agccgccgtt gaagacaagc
    13141 accacgtgac cgtccccgcg acaggcatca cgggtcccgc agccactgcc gcagacacgc
    13201 caacggccga cagggaaaca agagcagtgg cgatcaccgt gcgacgtcgc atgagcaagc
    13261 cttccgttgg acggctgcca gaattgccca taacaccccc aacatcgggt gaatgaacgt
    13321 tttcgcaccc gaagttcacc tgaaggcgtg aggccccgct ccagctgcgt ggcgacgaga
    13381 acgcccacgt cagtccacca catcggccac ctcgcgtgcg ggttccgtct caactacatt
    13441 caggaaccgg cgaacccgcc cggttccgag cggacggcgc agaagatccg ccgccaggag
    13501 cagggccacc agtacgccca ggagcaggtg atcgcgctca gagctccgcg gccgcggcgc
    13561 ggctgcgaca gaccgtccgg ctgacggtcg acgacggctc gcgagagagt ccccggctgg
    13621 cagcgccgga gctggatgcc gagagcggtc gggggctgtg gatcgttgcg gccatcgctt
    13681 ccgagtacag cggctcctgg ggtgtcagct ccgactgcag gaagacctgg tgctctctca
    13741 ccgtgcccgc agtgatggaa cctgccgtct gatggccgcc ttggagttca cgccggcgca
    13801 gcagacgtca gcggccgcac cggccatgga catgggtgac ctcgcggagc tggcccgctc
    13861 gcccagacat tcccaaagct ccgtccccag cggcatcgaa cgggccgccg ctcttcttcc
    13921 tccttcagta attcgaagcc cctgcatgcc cccggcgcgg gcccggtctg tcgggtgtcc
    13981 accgcggtac gcacccgaca gacctcattc cccgccccca ttcccgcagc cgtcaggtct
    14041 cttcgaggcc gcccgggaga cagactgatg acaaatcacc gcaccaagcg cgaggtctca
    14101 gagaatcgcg cagcagttat cgcccagaag gcgaccgtgg tccgccgata cacctacgag
    14161 ggcgcgtcta tggcggcgct ctgccgtgac tacggcgtgg gaatcggatg gctgcggcgg
    14221 cagttcgact cctgggacgt accccggcgc ccgcgcggac ggactgccta cgcagcagtg
    14281 caggagacat ccgccgatga cagggagcgg gcggcgcttg cgcagcgtct ggcggagccc
    14341 ggtctgctcg agcagagcct cgtcctcgat ctcagctcag ccccggtctc cggcgcaggc
    14401 gtgagcccgc tggcggtgcc cgtgggcggg gttcgcgtag cgggggaagt gaccgtcggg
    14461 aactggggcg aggcactgat cgtcattctg cagctggaag cacatccgga gcggtatccc
    14521 aaggtccgcc agcgtaagcc gctcggctcg ccgtgggagc cgagaactat ctgctggggt
    14581 acctctacac ccgtcgatga ctggcccacg cgaggccgca tgttcggcta ccacgaagcc
    14641 gggatcaacg aatacaccgc cgctcacgcc cagtcgtctg cacccctcgg ccagcgctga
    14701 ccgcaagttg cgctctccgc ccggagcagg gcaagtctgc gggaaacggc aggtaggagc
    14761 tgtgaatccg ttccgtccag taggcgcagt cggggcagga ggcgccggtg ggcgtgcacc
    14821 ggacctcgac acgtatcgcc tcgccgtccg tgtggacggc cacgaccgcg acgccgggaa
    14881 ccgatggaaa caacagttcg tgcagccggg acaatacctc gttcacggcc accgaatgtc
    14941 agccatacga cccgtgcgag gagcgatttc gaggcgactt ccgcatgccc cgtagctaga
    15001 tcaacaacta caacgcgtga ccggctcacg gaacttgtgc cagacccgac cctggcgaca
    15061 ggcacgaccc cgaggcccca cggcccgacg agacccaccc gccgtcggac cgccttcggc
    15121 gcccggacga cagcagcagc gcccgaacga caccccgaga accccaagag agaaggaggc
    15181 tccgcgtgtt catcgacatc ccgagcgaac tcgaagccgc tctgatcgac cgttctctcc
    15241 cgacgtggaa gctggacggt tcgttcctgg cgcagtccac catggaggag taccggaccg
    15301 agctgacggc caccccgcgg ttcgaggaaa ccgccgcgac gctgcgccac gcgctgaccg
    15361 gagagggcgg cggatacgcc gtgctgtgcc tcgggaacct cgccaaggcg ctggggaccg
    15421 acgccgaccg gttcctgcgg ctggtgacgg gcttcgcggc ggaggtggcc gtccccttct
    15481 cgcccttccc gcggtggccc ctgtggaagg acatcggggt caaggtcgac aaggaccccg
    15541 gcaagtccag cggcatcggg tacaacgcgt tccacatgga cctggtgaac gggaccctgc
    15601 ccccggacta caccacgctc ctgtgcgtcc gccccgaccc gctcggcggc ggccccagca
    15661 tcctctccga cgcccacgcg gcggtggcgc ggctgtcgga gaacagccgc gccctcctgg
    15721 ccgagacggc ctaccactac gggaccttct tcgacctgca cggcgtcggc gaggagtaca
    15781 agccgttccc gatcctgaac ggctccgacc cgggcgggtt cgtccggttc accgccaaga
    15841 tgctgaagag gtccgagctc ggcgaaacgc acgccgacgc cgccagggag ctcgccgagg
    15901 agctcgtccg gcagggcttc ggcgtagttg gcgggcgtcc gtttcgtgat cacttgagcc
    15961 cgagcagggc gagcgggcgg tccgcgttgc gggcgttgtg tcgcagcgcc gcggcgatgc
    16021 tggtcgcgcc ggccagccgt agggcgccga tggcgaggtt gcgccaggtg gccatcgccc
    16081 ggggcgcgtt gccggttcgc agctgtgagg cgtcttcggc gaacgtggtg tctctgacgt
    16141 ggtgcagggc ttcgatctgc cagtgatcac ggatcagggt cgccagctgg gcggggatgg
    16201 cttgctcagc ggtgaggctg gtgacggcgt agacggtctt gatggtggtc ttgccggtct
    16261 tgcggtcggt gcggcggcgt ttgatctgga cggcctgccg ggctccgggg aagagcaggc
    16321 tgttgaccgt gaccgccttg atccgtcgga tctccgagcg tccgtggccg gtgcccttca
    16381 cgcggccctg cagcgggatc tctgtccacg gaagggatct gagctgcttg cggagcttct
    16441 tctggttgcc cttgacgatc acgatgtagt gggcttcgcg gcccaggaga tagtcggcgt
    16501 gctcgcattg ggtgtgcatg gcgtcgctgg tgacgaccac cccggccagg tcggccatgg
    16561 cctccagcaa cggctggaag caggtgattt cgttcgtctt ttcctgcacg tccagctggg
    16621 ccaggaccag gccggtggtg tggtccaggg ctgcgagcag gtggatcctg cggccgttgg
    16681 ccctggccgc gccgcgaagg ctcttgccgt cgaccgccag gccgcgcagc cggccccggg
    16741 ttcggtggcg gcggtcggcg agccagcggc cgaccgccag gtccaatgcg tcgccgtcga
    16801 tccgggccag tagtcgtcgg accgtcgttt ccgcaggcag gcaccgtttg gggaacaggg
    16861 ggtcgaatcg cacgccgacg tgttccagca cgtggggcgg agcgtcggtg atccattcgc
    16921 cgaccgccag cagcgacgtc gcccccgcca gcaccgcgca ggcgaccagg gcaaggacgc
    16981 cgaccagagc gtggcgcact ccacggggat cacgcggatc gggcacctgg gcgaggcggc
    17041 ccagcagtcc gggcacttct tccggcgcgg cctctggatg ctcgcggagt tggtcaaggg
    17101 caggcgggat cagcgatgat gcttcggcag gcacggtctt ccaggcaggt cacggggcgt
    17161 cgagaactcc atgatcttgg aagccgtgcc tgttccgctc tccctgaccg accaacctgg
    17221 cggaccgtca tgaaccggac gcccggcgac tacgccgaag ccctggctcg tccgggggca
    17281 gatctccttc atgctccagc ccggggacta cctcatcgtg aaccagcgtc gcttcctgca
    17341 cggtcgggag gcgctccaca gcggtcagga gaccgtcccg gtcaccgaca cgcggctgct
    17401 cctccagttg ttcctgcgcg cgagagccgg cgctggctcg gccgcgtagc cggcagacgg
    17461 taccggtgac acgccgagtc ccccctgcgg gtccagccgc cgagcacgcg gcacggccac
    17521 ggggcgggcg ccacccggaa acggtcaggc accgggctcc ccgggctcgc gaacgggtgc
    17581 tagatgtgcg acttccgcac cgagtgccat gtcgccccgg ccagagcccg cgtcgaccgg
    17641 aacaccgaca ggtgctcgtg ctcccggtac agccgccagt tgtgctccac cagcgccagc
    17701 ttgttcgagg acagcgaccc cgcccggccg gccctgtaga ccgccagcgg ttcctgcaga
    17761 ccccgggcgg ggtgcccatc tctcatgatc gacagccaca gcgcgtagtc ctgacgcttc
    17821 ggcatgtccg gcatcagtcg cgtgcccagc accgtccggt cgtacatagc agtcagggcc
    17881 ccgatgtggt cctgcaccag catgtcgcgg tacgtcacgc gctcccgtgc cgcgaccacc
    17941 cgcccgttcg gcgtgaagtc gcaagcctca ccggtgtagt cgccagcgac cttgtagtag
    18001 gaggtgaacg tcagtggagc atcgccgtcg gcggcgaacg cgagctgccg ctccaccttg
    18061 ccgggtagcc acatgtcgtc gctgtccagg aacgccacgt actccccccg cgctcgcgcc
    18121 agggcgaggt tgcgggccct ggccgcgccg ccctgctcgg gcgccgcctg cgggcgcaca
    18181 cgctcgtccc ggcgggccag gtcctgcagc aggtccatgg agccgtcggt ggacgcgtcg
    18241 tcggtgacca gcagctccac gtcggggtgg gtctgtgcga gcacggagcg caccgacgcg
    18301 ccgagcgtcg ccgccgagtt gtgcacaggc atcacgacag acacgagcgg cacggctctc
    18361 ctcccagcac gaccagcaat gacggtatcc agcacggatt gtattcgagc gccctcgcag
    18421 ccgaaggagc agttcatgaa ggtcatcatc gccgggcagg gctatgtcgg gctgccgctc
    18481 gccgtgcgcg ccgccgaggt gggtcatcgc gtcgtcggct acgacgtgga cctgcaccgt
    18541 atcgagcagc tcacggccgg tgagtcgtac gtggaggacg tggcctcctc ccggctccgc
    18601 gcggtcctgg acaccggggc atactccgcg accgccgacg ccgctgcgct ggccggcttc
    18661 gacatcgcgg tgatcaccgt gccgaccccg ctgcgggacg gcgtgcccga cctgacctac
    18721 gtcgagtcct gcgcccggac cctgggcgag caccttcgcc ccggcgcgac ggtggtcctg
    18781 gagtccacga cctatcccgg caccaccgag gaactgctgc tgccgatcct ggagaagacc
    18841 tcgggcctca aaggcggggt ggacttcctg gccggattca gtcccgaacg catcgctccg
    18901 ggaaacaaga ggtggtcgtt cgacgggacg ccgaaattgg tgtccggaat cgacgccaga
    18961 tcactcgatg cgatcaaggg tttctacgac gccatctttc agaccacggt tccggtgtcc
    19021 gggaccaggg tcgccgagct ggccaagctg atcgagaaca tcttccggtt cgtcaacatc
    19081 tccatggcca acgagatggc gatgctggcc gcttccctcg gcgtgaacat ctgggaggcg
    19141 atcgacgccg ccgcgaccaa gcccttcgga ttcacgcggt tcaccccggg gccgggagtc
    19201 ggcgggcact gcctgcccgt cgacccgttg ttcctctcct ggaaggtcca gcaggagctc
    19261 ggcgcccctt tccgattcgt ggaactcgcc gacgacgtga accgccacat gcccgactac
    19321 gtcgtccggc gtcttacgga agcactcgac aagcgccgca tgaccatcag cgaatcccgg
    19381 atcctgctgc tcggcctgac ctacaaatac aacgccaccg accttcgcaa ttcaccttcg
    19441 gcacgggtcg ccgaacttct catcaacctc ggcgccgagg tccgcggggc cgaccccaac
    19501 atcccggacg gcgacgacac caagctgaac gtgccctggg tggatgcaag cccggaggag
    19561 gtcgcggccg ctgatgccgt ggtgctcctc atggaccaca cccgattcga cctcgcgatg
    19621 atcgagaaga acgcgcccta cgttctcgac tgccgaaacc gcctttccgg accgaacgta
    19681 gaaactcttt agcttctcga aatcccccgc cccgctgccg atcttccatc cccaggagtt
    19741 ctcttgcgcg acgaatggga acacgcccac acggactaca ccatgcccgc gcagcgtcaa
    19801 attcctgcct cgctggccga aagcgagagc gactggcgcc accacctgga acgctcaacc
    19861 cggatccacc ggcttgattg tggtgtgatc ggttcggggt cgtgcagggc gtgtcggggc
    19921 tgagttgcgg attcgggcgt ggggcggccg ctggtctgcc cagcctttcc acttttccgc
    19981 agttctcggg ccctttcggg caggtcggtc ggggagtgtc agggggctgg tggcgcgtgc
    20041 acgatgctga agagctgggt gaagtccgtg ctccagggcc agcgttcggg caggtgcagg
    20101 gtgaggcggc gggcggagcg ggccaggcgg gcgggcacgt tgatcaggtg gtcacggatg
    20161 gtggcggtgg tcgctctggc atggaacgtg ccggccagtg cgccagcggc gcgggtcagg
    20221 ttgtgcgcca gggcggccag ggcgagccac gcggcattgg cctggaaatg cccggagggt
    20281 gcgtgggcga aggcgctgtt cttgacatcc gcgatcacct gctcgacgac agcgtgccgt
    20341 cggtgatcac gctcggcatc gttcaaggag agcggggagt cggtgaacgc ggcgtggtag
    20401 cgccaggtgt caaacagcgt gccctgtccg gcggggacgg tgccagtgct caggcgtttg
    20461 acgcggcgca cgatcagacg ggcggtgacc tgctgcttct tcggcttgga agtgaaggcg
    20521 gtgtagccgg tctcggctat ctcggcgtcg gagatccagc actggccctc ctcgtcccag
    20581 accgccttgg ggtacttgat cggcatccag gcgtcctcat cgatgcgggc gatggcggcc
    20641 ttgacggaag cgttcatccg cacggtgatg gagaaccgcg cgcccagcgc ccggcaggag
    20701 ttgacgacat cggcgccgta gaacgccgag tccgcgcgca tcaccagcag gccattcgcg
    20761 ccgcaggcgc gggcggtgcg gatggtctcg gcgacgaacg ctgccgcccc gcgcgcggag
    20821 ttcgatggtc ccttgcgcag cctcgtggcg gcgatcaccg gggcggccag gggtgtggag
    20881 acgatgccga gcagcgcgtt caggcccttg accttgctgt atccgtaacc ggtgccctgc
    20941 ttggcgtagc cgtaggtgcg gcggatggtg tcatcgatgt ccacgtaggc gacctggtcc
    21001 gcgccgggca gcagcggggc gtgacgggcc agttcgggaa ggaaccggcg ggccacggcg
    21061 tgcaattgct tcacatgccc gtgcgtgaag gaacgcagaa acgaccccag cgtggacggg
    21121 gcccgcacac cggagaacag gcggcccatc gcgccgtgcc gtagccggtg catgtcatcg
    21181 atgctgtcgg cgcccgcgac catgccgccc accagcgaca tcactttcgc cgcggggaag
    21241 gcaccggtgc cgtccttcga ggccggcaga cggatgtact ccccgaccag tgcgggcaga
    21301 ccgcaccgct cggccaaccg caccaccggc tccaggccgc cgtacgcgat taggttcggg
    21361 tcgtcgaacg cggatgagac cgccgctgcg gcatgggaag attgcatctc ggaagtgcct
    21421 tgctgatcgc gcctgatgtg gtcctagaga aaccccatca tcgcaggtca caaggcactt
    21481 cttcgttccc cgagaaactg tccacagaca tcaagccggt ggatccaggc tcaaccccca
    21541 acggctggct gatacgacac aacgccatga ccgaagcgct cgtcagcgga aagccgatgt
    21601 acctgctgca caccaccaag gacatcaacg ccatccgcac cagccggcag ttgcacgtct
    21661 ccaccggatg cctggtcggg gccctgtact gctcgcctct cgccagtcag cgcgagggac
    21721 tgcgcccaca caacctcggc gcctacctga tgcggacgaa accctccatc acacccatga
    21781 tcttcgaggt caccccggat gccccgatcc ggcccaaagg cgtcgactac ctgcatctcg
    21841 gtaccatcca cctgcgtacc tacctgcgct accagagctt cctcaccccg gccgagaacg
    21901 accagctcga ccgcgccgtg ctggccgggc tgcgcgctgc ggccgtgttc ctcgacgtcg
    21961 ccctgcgcaa cgccgccggc catgccactc cggcacccga gttcatcgac cagttgtccg
    22021 acgccgtggc ccacgtgccg ttcctcggct acctgtactt cgaggttctg tccgaatacc
    22081 tgatgctcca ctccgttact ccggagacca agacccatgc ccaggcggga gagctgaaca
    22141 acaggctcta caaacgactc gccttcgccg ccgtggacgg catggaccag ttgttcgacc
    22201 tgacccgttt caatccgcgc catcaccggc tcgtccagct catcgaaggc atagaaccgg
    22261 atctcggccc gggagtcgcc gagtacgtcc ggcgacgact gtcccacctg ttcacccgga
    22321 ccgcgctgca cccatcccag gacgcggcat cggtcacctt ccagggcgct gatctcagta
    22381 cgatccagaa agccgcgcct ggactgatcg gccagatgat cttccgcgag atccgataca
    22441 tgccccgcta tcggcagttg taccactgct tcgagaaagc caaggctttt gaggcgtggg
    22501 actactggaa cagtgaggga ataccca
//
