LOCUS       NZ_CP041610            23532 bp    DNA     linear   CON 14-NOV-2023
DEFINITION  Streptomyces sp. RLB3-17 chromosome, complete genome.
ACCESSION   NZ_CP041610
VERSION     NZ_CP041610.2
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. RLB3-17
  ORGANISM  Streptomyces sp. RLB3-17
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Massive gene flux drive genome diversity within a population of
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-FEB-2020) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 12022941)
  AUTHORS   Tidjani,A.-R., Lorenzi,J.-N., Toussaint,M., Van Dijk,E., Naquin,D.,
            Lespinet,O., Bontemps,C. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2019) Dynamique des Genomes et Adaptation
            microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.10
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66.0x
            Sequencing Technology             :: Illumina MiSeq; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/14/2023 04:19:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 11,027
            CDSs (total)                      :: 10,924
            Genes (coding)                    :: 10,421
            CDSs (with protein)               :: 10,421
            Genes (RNA)                       :: 103
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 503
            CDSs (without protein)            :: 503
            Pseudo Genes (ambiguous residues) :: 0 of 503
            Pseudo Genes (frameshifted)       :: 178 of 503
            Pseudo Genes (incomplete)         :: 409 of 503
            Pseudo Genes (internal stop)      :: 52 of 503
            Pseudo Genes (multiple problems)  :: 128 of 503
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:01:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1289132
            Orig. end                         :: 1312664
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041610.2.
            On Mar 4, 2020 this sequence version replaced NZ_CP041610.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23532
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="guanidinotides"
                     /region_number="6"
                     /rules="(pgm1 and pgm_amidino)"
                     /tool="antismash"
     cand_cluster    1..23532
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(pgm1 and pgm_amidino)"
                     /kind="single"
                     /product="guanidinotides"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23532
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13532](-)"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13532)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(pgm1 and pgm_amidino)"
                     /neighbourhood="10000"
                     /product="guanidinotides"
                     /protocluster_number="1"
     misc_feature    complement(607..621)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            complement(796..2184)
                     /locus_tag="FNV62_RS06130"
                     /old_locus_tag="FNV62_06270"
     CDS             complement(796..2184)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_040423240.1"
                     /locus_tag="FNV62_RS06130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06270"
                     /product="IS1380 family transposase"
                     /protein_id="WP_144314448.1"
                     /transl_table=11
                     /translation="MQSSHAAAAVSSAFDDPNLIAYGGLEPVVRLAERCGLPALVGEYI
                     RLPASKDGTGAFPAAKVMSLVGGMVAGADSIDDMHRLRHGAMGRLFSGVRAPSTLGSFL
                     RSFTHGHVKQLHAVARRFLPELARHAPLLPGADQVAYVDIDDTIRRTYGYAKQGTGYGY
                     SKVKGLNALLGIVSTPLAAPVIAATRLRKGPSNSARGAAAFVAETIRTARACGANGLLV
                     MRADSAFYGADVVNSCRALGARFSITVRMNASVKAAIARIDEDAWMPIKYPKAVWDEEG
                     QCWISDAEIAETGYTAFTSKPKKQQVTARLIVRRVKRLSTGTVPAGQGTLFDTWRYHAA
                     FTDSPLSLNDAERDHRRHAVVEQVIADVKNSAFAHAPSGHFQANAAWLALAALAHNLTR
                     AAGALAGTFHARATTATIRDHLINVPARLARSARRLTLHLPERWPWSTDFTQLFSIVHA
                     PPAP"
     gene            complement(2711..2836)
                     /locus_tag="FNV62_RS57000"
     CDS             complement(2711..2836)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572089.1"
                     /locus_tag="FNV62_RS57000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_263985282.1"
                     /transl_table=11
                     /translation="MGGLSDTDAFEHDVCRALTEISPASTFDELVRTEAIAATRP"
     gene            2911..3597
                     /locus_tag="FNV62_RS06135"
                     /old_locus_tag="FNV62_06275"
     CDS             2911..3597
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS06135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_06275"
                     /product="hypothetical protein"
                     /protein_id="WP_143600240.1"
                     /transl_table=11
                     /translation="MESGLNDFWRDVMKLQEPPYREPVDDEVLHLQDQVAEAARDLARA
                     ISTRESAYRADGQEAPDGIALSPDWQLAYLYALHEIEGIARRLADGAARTAGGTGASYP
                     QLGAAWGITKQAARLRWPGAVRKPDDTSGEGEPFELWLSGGLAEIIQLPNEGGFIWKAT
                     GGNGTSGQAEEPYGNRTEAAAHAGAFLARHAAADDDPYGPDAAHAGCVEPHLGPDGYVD
                     CDGTPL"
     misc_feature    3684..3697
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.92"
                     /tool="antismash"
     gene            3697..4680
                     /locus_tag="FNV62_RS06140"
                     /old_locus_tag="FNV62_06280"
     CDS             3697..4680
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075545.1"
                     /locus_tag="FNV62_RS06140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06280"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_143607126.1"
                     /sec_met_domain="APH (E-value: 2.8e-19, bitscore: 69.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFRPVPRDPEAFQQSVTAEDIHAIALRAFGRSVRITSAVELGGG
                     MYNNTYRLLAEGLDGPVILRIAPAPQRQFASEHELMRNEYATVPFLAPIADLVPRVLAA
                     DWSQEITGRDWMVQSHLDGTPAPDRLGDYPRTLWQGFFAQLGTITRNIHAVAGPRFGPV
                     AGPGYATWSEAVLASLTAIADDVSRVGLDAADVRKAADLAAEHHKVLDEITEPRLLTGD
                     LWTVNTMLAAAPTPVISGVLDLDRTLWGDPAADWTIRMASAKTDERTAFWDTYGPRAAT
                     SAHAWRALVYEARHLGAIRLERHRLHNPSGVDDTYSSMAAVLAQLI"
     gene            complement(5026..5319)
                     /locus_tag="FNV62_RS06145"
                     /old_locus_tag="FNV62_06285"
     CDS             complement(5026..5319)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS06145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_06285"
                     /product="hypothetical protein"
                     /protein_id="WP_143600248.1"
                     /transl_table=11
                     /translation="MTWLFTATIRSVRQLVTVFCRSCLLLLCRSTDGGTDGGNSMDITA
                     WVVLVPVVAMLIAAIAAVVIVVVAVQDTTACARAEVLKAVAEVIRAVRGSRR"
     gene            5382..7880
                     /locus_tag="FNV62_RS06150"
                     /old_locus_tag="FNV62_06290"
     CDS             5382..7880
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017539.3"
                     /locus_tag="FNV62_RS06150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06290"
                     /product="NACHT domain-containing protein"
                     /protein_id="WP_143614218.1"
                     /transl_table=11
                     /translation="MSEPIQLPVGRRVLRDELRMLERKALQREGKNRTDAIEKANAQLE
                     PLGLPKLKTSTVSDWIEKGNPAKNFLVLWALVRVFLEWSGGLPPKGATTPKDPVGAKAK
                     AAWNYTEEGWRLRWEDAKRSRPPTPAPENARLLTAYLRAARDAAGQHPYRSTRQDLKLP
                     ALADVYVRQHTRTRAQGNEASAAVPAAQVFRADHSICLLLGAPGGGKSTLLRTHLAQTA
                     EALLSNTAEKTIPILLRAAALTTTDPLPAALARTVTADLQQDGLLDELPTGFFRRPPRT
                     GASWLVLVDGLDEIPDTDTRSAVMTKLANVSANSEGLYRFVVATRPLPAQELLKLGDRV
                     AHYELQPFSHDDLYTYATHWFRSLDNPRRHTEAFIAGLTHSGLEVLARTPLMALMLCQL
                     YLTDPTRPLPAGRAGAYQEFVKWIYEQNTHKNIKNTHDQAIRRLKDRHQIPEESDAAES
                     AAEQVRQHLRGLIDHLAYERLNGRRGAAVDILASHLQVNRPREVEQHLWNAFLGDLMRP
                     TGILTQHGDDFDFLHQTLLEYRAARHATRNEQTCTQLLNDLIASSTVRSDGRLAPPAVA
                     DSYLGFLLDGLSAFHGRIAAETTRYVVEIMQHGGEGTHRFLTTQVYLKTNLPPGPTAVC
                     LARLADNPALDGLARVTAARALAEVDSNAGAHHLARLANDPTLNDGSHLEAARALAEVD
                     SKAGAHHLARLANDPTLNDDFRVRAARALAEVDSKAGAHHLARLANDPTLNDSFRVEAA
                     RALAEVDSKAGAHHLARLADDPTLNDSFRVEAARALAEVDSKAGAHHLARLANDPTLDD
                     FSSGRAARVLAQTEARGRGR"
     gene            complement(7954..8760)
                     /locus_tag="FNV62_RS06155"
                     /old_locus_tag="FNV62_06295"
     CDS             complement(7954..8760)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (60-178). E-value: 1.7e-08. Score:
                     24.9. Matches aSDomain: nrpspksdomains_FNV62_RS06155_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.3"
                     /locus_tag="FNV62_RS06155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06295"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_143614220.1"
                     /transl_table=11
                     /translation="MSTPPAGRAADTAGHQTTSALEFDRLFGTEGTEGHGSAFSTIARL
                     VDPDLPPDLDLFSFLCADLLHHLARQLDLRPRQILADLGCGRGGPGLWLAGRAHATLVG
                     IDFSPVAIAQARHRAVPFAADAAFAVADLALLPLTSQCVDEALSLDALQYAPDRVAAAR
                     QVLRILKPGGRLVLTGWHPHTPGDERLPPRHRHTDRTRVLHTAGFTDVHCTSTPAWDDA
                     YQGIYRTALTLHAEPGSALAGLQGEARRRLPTAHLLRRVAVTAVRD"
     aSDomain        complement(8227..8580)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FNV62_RS06155_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.70E-08"
                     /label="FNV62_RS06155_oMT.1"
                     /locus_tag="FNV62_RS06155"
                     /protein_end="178"
                     /protein_start="60"
                     /score="24.9"
                     /tool="antismash"
                     /translation="CADLLHHLARQLDLRPRQILADLGCGRGGPGLWLAGRAHATLVGI
                     DFSPVAIAQARHRAVPFAADAAFAVADLALLPLTSQCVDEALSLDALQYAPDRVAAARQ
                     VLRILKPGGRLVLT"
     gene            complement(8757..10004)
                     /locus_tag="FNV62_RS06160"
                     /old_locus_tag="FNV62_06300"
     CDS             complement(8757..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014805.3"
                     /locus_tag="FNV62_RS06160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06300"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_143607128.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.2e-12, bitscore:
                     47.4, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4e-10, bitscore:
                     38.8, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVPVMLLEAAGPESEALARTAAAAGHPVHAVTDAATLASYSGEL
                     RQLLEGCLVTGFTRPGQAVADITGYGRRIGVKALLTVNEYLTEVAARSCAALGLPGNDP
                     ERAAAARNKALMATAFEAGHVTMPRTKAVADLRELRGLHEAGAVGFPCVVKPADGAGSA
                     GVTVVTGPEELEPAWHAARTARVMYGMLRDERILVQEHVQGREFSVEYITQHDVTTHLC
                     ITRKHTTSGIHRVELGHTLPARLPAAAERALLEQAGRAIAAVGVRNGATHTELVLSPDG
                     RCTVLEIGARLGAGHIGVLMQHALGIDPWRTVWDIALGRPVTITQAPGGYATVRFLTTH
                     HAGRLVAVTGLPAVTTTIPAVRVRAAEGSDVGPATSNRGRLGHVIVTGHDPRTVDERAD
                     QILRQITITVAPGSRT"
     gene            complement(10001..11146)
                     /locus_tag="FNV62_RS06165"
                     /old_locus_tag="FNV62_06305"
     CDS             complement(10001..11146)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm_amidino"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016827973.1"
                     /locus_tag="FNV62_RS06165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06305"
                     /product="glycine amidinotransferase"
                     /protein_id="WP_143614222.1"
                     /sec_met_domain="pgm_amidino (E-value: 1.6e-170, bitscore:
                     566.1, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTLNSYDDFTPLSEIIVGSAENYVGHDRDLTFELFFHEAIGGYR
                     SDWAYPRLAAGGSEQAETWKIGKRYTEELHEDVENLAATLTSLGITVHRPLPLPTDALP
                     IAGLGWQAAPTPALNVRDNTLVLGDEIIETPPAVRSRYLETRLLSQVFRSYFDTGARWT
                     TMPRPVLTDRSFDLSYAQSAATTLGGPTEPITDPQPSPYDVGVEMMLDGAQVLRLGQDL
                     IVNVAQDNHRLAVDWLKRHVEGRFRVHTVYRMADNHIDSMLLVLKPGVFLARHAGLREI
                     LPDAFRTWTFIVPPEPEPGQFPVYTDSELLLTSPYIDINVLSLDEQRVLVNADCLGLIK
                     TLENEGFTVIPVQHRHRRLFGGGFHCFTLDTHRAGGLVDYR"
     misc_feature    complement(10838..10840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11167..12144)
                     /locus_tag="FNV62_RS06170"
                     /old_locus_tag="FNV62_06310"
     CDS             complement(11167..12144)
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016974.3"
                     /locus_tag="FNV62_RS06170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06310"
                     /product="aspartyl/asparaginyl beta-hydroxylase
                     domain-containing protein"
                     /protein_id="WP_143607130.1"
                     /transl_table=11
                     /translation="MTTTTPARPAPAAPLTPAFDADRLAHELSAVTGHPWQRQRTHYAA
                     GRIGPDTPTDWRVLPLRSPGGDPTRTDPGGPGPDHYAATRWLDQMPYLREILDEIPAPL
                     NAVRLLALGPGAASQPHRDPKYALQRGMVRLHIPIATHPGAVLVLDGTEHRWQPGTFWY
                     GDFSREHMVANTGSVRRVHAVIDALFTRELATLFPTEWQESLGYADVLFNRLPDPALRP
                     SPPLPRAVNLPAGFTDFSQDTPLEGPTVPVRLTERDGDLVLTHAERGFALVHVVDGEYR
                     YAGWSEQRTLQLGNDHVVLHARHGRALTSQHVSLPAADSSPAGA"
     gene            complement(12141..13532)
                     /locus_tag="FNV62_RS06175"
                     /old_locus_tag="FNV62_06315"
     CDS             complement(12141..13532)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     guanidinotides: pgm1"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF037360.3"
                     /locus_tag="FNV62_RS06175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06315"
                     /product="hypothetical protein"
                     /protein_id="WP_143607131.1"
                     /sec_met_domain="pgm1 (E-value: 5.8e-136, bitscore: 452.7,
                     seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIIIANHIDPAIRDRHDLRAWTQRALWGARNGDLVVLCAPPDPH
                     FLRYATALTGTDPNRLHLVVAPTGAYGGRLLDPQMLTHPDTLDQVRAYLAKHGGPDAVG
                     EIWALWPSASVARFATALGLTEKLPGCDFLAQGGGELVNNKAVFRTLAAAAGVPVAAGT
                     VVRDPGEAAAATLTLLQRSGAVVVKQAHNGAGVGNELLVTDPTLATGHAGARHLHHLGR
                     TDLPAAAAAYWRERWTWASADGRFPVVLEEFIPGAFTVYCEQHLTETGTQPTERGELRY
                     TDRRLSHESVPLRDLSAAVEEQLLDGSARLAHTYRSVGYRGRISTDAIVGPDGRLLFTE
                     VNAQVSGSWHIYEVFAHHIVHANETPERTVTESHIPPEWTLPDGSTFHRALAELGLGYD
                     PATRSGVIVSMPIVDHPSLGAQFTFSTVHASPADRDAIWHALEDRFTTTSSTARRTDSR
                     KALAR"
     misc_feature    complement(13518..13533)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.14"
                     /tool="antismash"
     gene            complement(13567..14748)
                     /locus_tag="FNV62_RS06180"
                     /old_locus_tag="FNV62_06320"
     CDS             complement(13567..14748)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.3"
                     /locus_tag="FNV62_RS06180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06320"
                     /product="cytochrome P450"
                     /protein_id="WP_164657610.1"
                     /sec_met_domain="p450 (E-value: 2.2e-10, bitscore: 39.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTPTCPVRYDPLDEATLADPYPVLAALRAQAPLVWHDTMESWL
                     VTGYDDCVRVLRDHEAFARDPRRLGRTVPEASLSVQVLDPPHQAAVRSAFMTSLHAQDL
                     PVLQERTRRDIAARLEVLASQPAWDVMRELAQPVALDAIADLLGVTPPPLSAWVQVSDT
                     IMRSMDGGLNPDLVEPGRLAREKLSELVASWFTTTGSPAGLLGHVRTRTADAGPELARY
                     VVHTARVMFQGGYSTLAAAIGNAVDTLARNPQAQRALRETPQLRATGVDELVRYDGPVQ
                     GTSRLAATDVLLGGRTVHRGEKVTVLFQAANRDPAHFEHPDRLVLDRSPNRHLGYGWGT
                     HACLGTTLAQRVLVALLDALADHPGLLHPAGPARRRHTATMRAFDHLPVTLQP"
     gene            15031..16347
                     /locus_tag="FNV62_RS06185"
                     /old_locus_tag="FNV62_06325"
     CDS             15031..16347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383632.1"
                     /locus_tag="FNV62_RS06185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06325"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_143607133.1"
                     /transl_table=11
                     /translation="MEETTGHPLVVARHAAGKTMEEFVSGIHASAARRNLRSGIDEARV
                     RKWQRGVQPSEESQIYIAEALGWPADIVRADDWPNWLPLTANGVVPLGPHSSVPALREA
                     QRTAMERRTFLTISGAALSALAADWAGGPADALAQAHDGKPIGEDLVAFLENSTRHLAG
                     LSTEQRQHTPALLDAHLATVTELLENGRYTPALGLRLHTLAASLSQTVAWHAFDLGRHT
                     HASQSWVAGLHNAHAAGDHDMGAGLLGDLAYQAAWRRDHITAASILGHALTRAQNPAAR
                     CLLQLRLARTLAARGDRSERRAVLRALAAAEKHLNDAGTERPAWCAWVGAADLAVDSGQ
                     ALLDLGDTARAHQLITEGERLLPTARDKTRGVFLAYRAASYLDLKEPEAAAAAATQSLL
                     LARRIGAPRCVQLVDDLLPRFQPYARAQGVPELLQLTAA"
     misc_feature    15490..15492
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16690..16869
                     /locus_tag="FNV62_RS06190"
                     /old_locus_tag="FNV62_06330"
     CDS             16690..16869
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS06190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_06330"
                     /product="hypothetical protein"
                     /protein_id="WP_143600258.1"
                     /transl_table=11
                     /translation="MLSLLDGCTAKDATFVVMGDDSLWTARSAWTDAQRSLIQEYTGSD
                     RRAGKDRTYADGDS"
     gene            complement(17182..17784)
                     /locus_tag="FNV62_RS06195"
                     /old_locus_tag="FNV62_06335"
     CDS             complement(17182..17784)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS06195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_06335"
                     /product="hypothetical protein"
                     /protein_id="WP_143600259.1"
                     /transl_table=11
                     /translation="MTVAHDAYVRQLIARAKDGTIPPQEVKQIAQAVTECRAGRELYQR
                     LYAVARAGGPAYEPLIAAYLIYPEDPEVSALAVQVLTAHWRVGAKYRKQILELLGSPEW
                     DLDDDVFMAAVSGAGWILHDGFDAELLRALLKLAEEGRGEYNDDLMQGLAVEATARALG
                     ASHAELTRLPEGVTRAEWSQGLLRAARDRLHEAARQP"
     gene            complement(17946..18296)
                     /locus_tag="FNV62_RS06200"
                     /old_locus_tag="FNV62_06340"
     CDS             complement(17946..18296)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS06200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FNV62_06340"
                     /product="hypothetical protein"
                     /protein_id="WP_143600260.1"
                     /transl_table=11
                     /translation="MNPLEDDLKQVRVELAAAELESQRLEAQIAALRAKEATLEGLIVK
                     APELNVQGMTKAEAIVAALAQSSEPMTLGQIADTVTAAGSVLKPDGASVYLDGLLKMGK
                     VVRVKRGLYRAA"
     gene            18727..19110
                     /locus_tag="FNV62_RS55405"
     CDS             18727..19110
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017416.3"
                     /locus_tag="FNV62_RS55405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_225900164.1"
                     /transl_table=11
                     /translation="MQVARASNPGGTTAIWVRDRLDGLWCDEDFADWYPRDGRPGLSPA
                     QLATVCVLQFLLGLSDRQAAEAVRCRIDFKYAMAMELDDPGFHHSVLADFRDRLAEGDR
                     ADRLLDLALARLKEAGLVRERTT"
     gene            19141..19959
                     /locus_tag="FNV62_RS55410"
     CDS             19141..19959
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FNV62_RS55410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_225900165.1"
                     /transl_table=11
                     /translation="MRDLTRLELITEAVRAALEEVAGTSPHLLDELVDEDWGLRYGRPV
                     RLGKNPTRPKTRILATGNDAVRVLEHLYRHGTDHTFGPRIQALRQIMVQNYHHDGAGHL
                     RWRTAETEGDPGLPPSSLAVVSPYDTSARYARHGHIISWKGFSAHLTETCAPDGPNVIT
                     DVATTAATTHDSQVLPGIHTRLARRGLLPAEHLVDAGYTSLPHLEQATREHQVTVSGPL
                     RSDPTRQHRRNEGFARDDFHIDYDRQQVTCLQGQGVGTAPTRPPLPPRPR"
     gene            19962..20381
                     /locus_tag="FNV62_RS55415"
     CDS             19962..20381
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.3"
                     /locus_tag="FNV62_RS55415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_225900166.1"
                     /transl_table=11
                     /translation="MARFAKSQCRPCPARTQCTSTADSARTVGFPPREPRDLQLRVRAE
                     QQTLEWKTRYAVRSGVEGTVNEFAHGHGMRRCRYRGQGKAHIQHVLTAIAVNIERLSEL
                     PPTEETPTPRRPTALQNYLDQREIRRLKSWRTLGS"
     misc_feature    20699..20714
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            20818..21936
                     /locus_tag="FNV62_RS06210"
                     /old_locus_tag="FNV62_06350"
     CDS             20818..21936
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983601.1"
                     /locus_tag="FNV62_RS06210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FNV62_06350"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_225900167.1"
                     /transl_table=11
                     /translation="MARSPQERGVPHSAGARDRLLPVLPALLLFGGLLFGLFTPRDVRP
                     DAFLATAMVSAAALLSLRGTVLTGVGACAIFVCLMVDFNGLRDATAYSELATLVAIAAF
                     AVFFNRLLGRRAHQLVQVRSVAETAQLAVLHPVPRHLGHVTLESLYLAAAAEARIGGDL
                     YEAIRTPHGVRLLIGDVRGKGLLAVRTAATLLSAFREAAHDAPDLPHLACRLETSMSRH
                     ASQYPGVPGSEIAERFITALLAEIPDDEPVVRTVTCGHPPPLLLHRGEVRELQPAAPSP
                     PLNLGMLMSDGYHVDLAPFHPGDQLLLYTDGVTETRDRSGTFYPLAERIRSWSGEAPHQ
                     LLDHLHRDLITYSGGELHDDIAALVARRRPNR"
     misc_feature    20849..20865
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    complement(22261..22279)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 22.77"
                     /tool="antismash"
     misc_feature    22617..22633
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    22653..22667
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.38"
                     /tool="antismash"
ORIGIN
        1 cggctattga tggagccttg ttcatgagcc ccggaacgat gctggctccc gcgcagaagg
       61 cggagccgag gatggcaccg gacgcggtgg cagcactcga tatacaggca ccgatcaacg
      121 ccactgcgat caagagaacg aaagctaggg ctgcttccgc gagaaactgc ccgggcatgt
      181 cagagagcga acagcactcg gagagggtga cggtcttggt cgcgtcggcg actgtgcttg
      241 tcagcgtggt cttttgccac ggcatccagg tgccgatcaa ccatccgata gccaagacca
      301 tgccagtaat cgcccagaag atgccgaccc gggtggcgcg tattcgcagg gcaccacagc
      361 gtcgcagagc gatgagagcc aaaaccgcgc tcgccaggca cagggcgcaa gaggtgattc
      421 cccaccagta acccggaccc ggactgtagt acgtggcgga gccgtcggtg ccgctccgca
      481 agaagtcggt ggtgtccgag atgaactgag cagccgtgag caacccggcg ccgaccagca
      541 tgccagcacc gaacctgctc gtgcgcgaaa ggaaggcgag gagagccgcg attacgatgg
      601 aaccaatgaa aacggcgttg aaggcgacag ttgagcccgg atccaccggc ttgattgtgg
      661 tgtgatcggt tcggggtcgt gcagggcgtg tcggggctga gttgcggatt cgggcgtggg
      721 gcggccgctg gtctgcccag cctttccact tttccgcagt tctcgggccc tttcgggcag
      781 gtcggtcggg gagtgtcagg gggctggtgg cgcgtgcacg atgctgaaga gctgggtgaa
      841 gtccgtgctc cagggccagc gttcgggcag gtgcagggtg aggcggcggg cggagcgggc
      901 caggcgggcg ggcacgttga tcaggtggtc acggatggtg gcggtggtcg ctctggcatg
      961 gaacgtgccg gccagtgcgc cagcggcgcg ggtcaggttg tgcgccaggg cggccagggc
     1021 gagccacgcg gcattggcct ggaaatgccc ggagggtgcg tgggcgaagg cgctgttctt
     1081 gacatccgcg atcacctgct cgacgacagc gtgccgtcgg tgatcacgct cggcatcgtt
     1141 caaggagagc ggggagtcgg tgaacgcggc gtggtagcgc caggtgtcaa acagcgtgcc
     1201 ctgtccggcg gggacggtgc cagtgctcag gcgtttgacg cggcgcacga tcagacgggc
     1261 ggtgacctgc tgcttcttcg gcttggaagt gaaggcggtg tagccggtct cggctatctc
     1321 ggcgtcggag atccagcact ggccctcctc gtcccagacc gccttggggt acttgatcgg
     1381 catccaggcg tcctcatcga tgcgggcgat ggcggccttg acggaagcgt tcatccgcac
     1441 ggtgatggag aaccgcgcgc ccagcgcccg gcaggagttg acgacatcgg cgccgtagaa
     1501 cgccgagtcc gcgcgcatca ccagcaggcc attcgcgccg caggcgcggg cggtgcggat
     1561 ggtctcggcg acgaacgctg ccgccccgcg cgcggagttc gatggtccct tgcgcagcct
     1621 cgtggcggcg atcaccgggg cggccagggg tgtggagacg atgccgagca gcgcgttcag
     1681 gcccttgacc ttgctgtatc cgtaaccggt gccctgcttg gcgtagccgt aggtgcggcg
     1741 gatggtgtca tcgatgtcca cgtaggcgac ctggtccgcg ccgggcagca gcggggcgtg
     1801 acgggccagt tcgggaagga accggcgggc cacggcgtgc aattgcttca catgcccgtg
     1861 cgtgaaggaa cgcagaaacg accccagcgt ggacggggcc cgcacaccgg agaacaggcg
     1921 gcccatcgcg ccgtgccgta gccggtgcat gtcatcgatg ctgtcggcgc ccgcgaccat
     1981 gccgcccacc agcgacatca ctttcgccgc ggggaaggca ccggtgccgt ccttcgaggc
     2041 cggcagacgg atgtactccc cgaccagtgc gggcagaccg caccgctcgg ccaaccgcac
     2101 caccggctcc aggccgccgt acgcgattag gttcgggtcg tcgaacgcgg atgagaccgc
     2161 cgctgcggca tgggaagatt gcatctcgga agtgccttgc tgatcgcgcc tgatgtggtc
     2221 ctagagaaac cccatcatcg caggtcacaa ggcacttctt cgttccccga gaaactgtcc
     2281 acagacatca agccggtgga tccaggttga ggatgagtcc ttgagtcgct gagcagtagc
     2341 gtcagccccc tggtacccgt agaccgggaa caatgcagcg agtgtgcaaa cagcggccgc
     2401 gattcccagc gctgcggcag acatacgcca ggcaggtgga ggagcctcga cgtagacggc
     2461 cgtgggccct ttcaggggtt gtccgcaacg ggtgcagtag accccttgcg gtatggctgg
     2521 agtgccacag gacgtgcaga acatgtatcc ctcgccagct ggttccagcc cccgacgagg
     2581 gcgcgagcgg acatcgtact ggcagcggac tctcgaatca ggagaccggg tcctcgacga
     2641 cgttcgacgc cttggtgatg aactccatgg gaagctcagc gtgcatggcc cggttccggc
     2701 gggagggacg tcagggacgg gtggcggcga tggcttccgt ccggacgagc tcgtcgaacg
     2761 tgctggccgg gctgatctct gtcagggccc ggcacacgtc gtgctcgaag gcgtccgtgt
     2821 cgctgaggcc ccccatgagt cagtggcgag gggcacaact ggcgacaagt ccacttgtca
     2881 ccaactgttg cgacaagtat tcttgtcgct atggaatccg gtctgaacga cttctggcgt
     2941 gacgtcatga aactgcagga gcccccgtac cgagagcccg tcgacgacga ggtcctgcac
     3001 ctccaagacc aggtggcgga ggccgcccgc gatctggccc gtgcgatctc cacgcgggag
     3061 tccgcctacc gcgccgacgg ccaggaagcc cccgacggga tcgctctctc gccggactgg
     3121 caactcgctt acctgtacgc ccttcacgag atcgagggca tcgcccggcg gcttgccgac
     3181 ggcgcggcgc gcaccgctgg cggcaccgga gccagctatc cccagctcgg ggcggcctgg
     3241 gggatcacca agcaggcagc gagactgcgc tggcccggcg ccgtgcgcaa acccgacgac
     3301 accagcggcg aaggtgaacc gttcgagctg tggctcagcg ggggtctcgc cgagatcatc
     3361 caactcccca acgagggagg gttcatctgg aaggccacag gaggcaacgg caccagcggt
     3421 caggccgagg aaccgtacgg aaaccggacc gaggccgctg cgcacgccgg cgccttcctt
     3481 gcccgccacg ctgccgcgga cgacgacccg tacggtcctg acgcggcgca cgctggctgc
     3541 gtcgaacccc acctcggccc cgacggctac gtcgactgcg acggcacacc cctgtgaatc
     3601 cgcgcggcac gaaagacgcg ggagcactgc cgatctggcg cacagcaagc atgcgatgac
     3661 cgatccggcc ccggacaagg ccgtataagg agtgtcatgg acttccgccc cgtcccccgc
     3721 gaccccgaag ccttccagca gtccgtcacg gccgaggaca tccacgcgat cgctctgcgt
     3781 gccttcggcc gcagtgtccg catcacctcg gcggtcgagc tgggaggagg catgtacaac
     3841 aacacctacc ggctcttggc ggaaggcctc gacgggccgg tcatcctgcg tatcgccccc
     3901 gctccgcagc ggcagttcgc cagcgagcac gagctgatgc gcaacgagta cgccaccgtc
     3961 cccttcctcg ctcccatcgc cgacctcgtt ccgcgggtcc tggccgccga ctggtcgcag
     4021 gagatcaccg gccgggactg gatggtgcag agccacctcg acggcacgcc cgcccccgac
     4081 cgtctcggcg actacccccg cactctctgg cagggcttct tcgctcagct cggcacgatc
     4141 acgaggaaca tccacgccgt agccggcccg cgctttgggc ccgtcgccgg acccggctac
     4201 gccacgtgga gcgaggccgt gctggcctcc ctgaccgcca tcgcggacga tgtcagccgc
     4261 gtcgggctgg acgccgcgga cgtgcgcaag gccgctgacc tcgccgccga acaccacaag
     4321 gtcctggacg agatcaccga accccggctg ctcaccggcg atctgtggac cgtcaacacg
     4381 atgctcgcgg ccgcacccac gccagtcatc agcggtgtcc tcgacctgga ccgcaccctg
     4441 tggggcgatc cggctgccga ctggaccatc cgtatggcca gcgccaagac ggatgagcgc
     4501 acggcgttct gggacaccta cgggccccgc gccgccacgt ccgcccatgc atggcgggcc
     4561 cttgtctacg aggcacggca tctgggggcg atccggctgg agcggcaccg cctccacaac
     4621 ccctccggtg ttgacgacac atactcctcc atggccgccg ttctggccca gctgatctga
     4681 acgttgctgc ctactgccga gttctaggat ccgcggctcc gctagcaatg aaggcagtcc
     4741 gtgagcagca gattcgcaaa tccgcgatcc cggtgacaat gactacgttc aggggcgatc
     4801 tccgccgggt ctctttcgat cttctctgcg cgtgtgctgc ccgtgctccg tatcgtcctt
     4861 cctggctggc aactgctcgc ctttctcggg cggctgtaac gagcgtgtca tcagccgcca
     4921 aacaggcgtg attgacagtt ctgtggtctc gaccaaaaca cttcggcatc atgttcgggc
     4981 atggggcggc agccagtggc gatggaggac acctcgcggc ggacgtcatc ggcggctgcc
     5041 gcgtaccgca cggatcacct cggcgactgc cttcaacacc tcggcgcggg cgcacgcggt
     5101 ggtgtcctgc accgcaacca cgacgatcac tacggcggcg atagccgcga tcagcatggc
     5161 gaccaccgga accaagacga cccaggcagt aatgtccatg gaattccctc cgtccgtgcc
     5221 gccgtctgtc gagcggcaca gcaaaaggag acaggagcgg caaaagacag tcacgagttg
     5281 ccggaccgac cggatcgtgg cagtgaacag ccaggtcacg gccgagccca ccactccgcc
     5341 cgccggactc gccggacgcg tcacaagagg gagggcgccc ggtgagcgag ccgatccagc
     5401 tgccagtcgg ccgacgggtc ctgcgcgatg aactacggat gctggaaagg aaggcacttc
     5461 agcgcgaggg caaaaaccgt acggacgcga tcgagaaggc aaacgcacag ttggagccac
     5521 tcggcctacc gaagctcaag accagcacgg tgagcgactg gatcgaaaag ggcaatccgg
     5581 cgaagaactt cctagtgctg tgggccttgg tccgggtgtt cctggagtgg tcggggggcc
     5641 ttccaccgaa gggagccacc acccccaagg accccgtcgg tgccaaggcg aaggcagcct
     5701 ggaactacac cgaggaaggg tggcggcttc ggtgggagga tgcgaagagg tcccgccccc
     5761 cgactcccgc gccggagaac gcacggctgc tcactgcata cctgcgggcg gcacgcgacg
     5821 ccgccggaca gcacccttat cgcagcaccc gccaggacct caaactgccc gcgctggccg
     5881 acgtctacgt gcgccagcac acccgcacgc gcgcccaggg caacgaggct tccgccgccg
     5941 ttcccgctgc ccaagtcttc cgtgctgacc acagcatctg tctgctccta ggcgctcccg
     6001 gcggcggcaa atccacgctg ctgcgcaccc acctcgctca gaccgccgag gccctgctct
     6061 ccaacacggc cgagaagacg atcccgatcc tcctcagagc ggctgccctc accaccacgg
     6121 acccgctccc cgcagccctc gcacgcaccg tcaccgccga ccttcagcaa gacgggctgc
     6181 tcgacgagtt gcccaccgga ttcttccgcc gccctccacg taccggggcg tcctggctag
     6241 tgctggtcga cggcctcgac gagatccccg acaccgacac ccgtagtgcc gtgatgacga
     6301 agctggccaa cgtctccgcc aacagcgaag ggctgtaccg gttcgtcgta gcgacccgcc
     6361 ccttgccggc acaggaactc ctcaagctcg gcgaccgcgt tgcgcattat gaactgcagc
     6421 cgttctccca cgacgacctg tacacctacg ccacgcactg gttccggtcc ctggacaatc
     6481 ccaggcgcca caccgaagcg tttattgccg ggctgacgca ctccggcctg gaggtcctgg
     6541 cccgcacccc cctgatggca ctcatgctgt gccagctcta cctgaccgat cccacgcgcc
     6601 ccctgcctgc cggccgtgcc ggcgcgtacc aggagttcgt caagtggatc tacgaacaga
     6661 acacccacaa gaacatcaag aacacccatg atcaggcgat tcgccggctg aaggaccgcc
     6721 accagatccc cgaggaaagc gacgccgcgg aaagcgctgc cgagcaggta cggcagcacc
     6781 tgcgggggtt gatcgaccac ttggcctacg aacggctcaa tggcagacgc ggtgcggccg
     6841 tcgacatctt ggcctcacac ctgcaggtca accggccgcg ggaggtagag cagcatctgt
     6901 ggaacgcctt ccttggcgac ctcatgcggc ccaccggcat actgacccaa cacggggatg
     6961 acttcgactt cctccaccag acgctcctcg aataccgtgc ggcccgtcac gccacccgca
     7021 acgaacagac ctgcacccag cttctcaacg acctgatcgc gtcctcgacc gttcgctccg
     7081 acggccgcct agcaccgccc gcagtcgccg actcctacct cggcttcctc cttgacgggc
     7141 tcagcgcctt ccacggccgc atcgccgccg agaccacccg atatgtggtt gagataatgc
     7201 agcacggagg tgaaggcacc catcggttcc tcaccaccca ggtctatctg aagaccaact
     7261 tgcccccagg ccccactgcc gtgtgtctgg cccggctggc tgacaacccc gccctggacg
     7321 gcctcgcgcg tgtgacggcg gcgcgggcac tggcggaggt ggacagcaat gccggcgccc
     7381 accacctggc ccgcctcgcc aacgacccca ccctcaacga cggctcccat ctggaggcgg
     7441 cgcgggcact ggccgaggtg gacagcaaag ccggcgccca ccacctggcc cgcctcgcca
     7501 acgaccccac cctcaacgac gacttccgtg tgcgggcggc gcgggcactg gccgaggtgg
     7561 acagcaaagc cggcgcccac cacctggccc gcctcgccaa cgaccccacc ctcaacgaca
     7621 gcttccgtgt ggaggcggcg cgggcactgg ccgaggtgga cagcaaagcc ggcgcccacc
     7681 acctggcccg cctcgccgac gaccccaccc tcaacgacag cttccgtgtg gaggcggcgc
     7741 gggcactggc cgaggtggac agcaaagctg gcgcccacca cctggcccgc ctcgccaacg
     7801 accccaccct ggacgacttc tccagtggaa gggcggcgcg tgttctcgcc cagacggagg
     7861 cgagagggcg cggtcggtga ttctgtgcac gcaccgtgcc cgcgacggtg tagcggcaca
     7921 ttgcgccctc gcgtttgctg cggctgcctc cgttcagtct cgtacggcag tgacggcaac
     7981 gcggcgcagc aggtgcgcgg tgggcaggcg ccgacgagcc tctccctgca gtccggcgag
     8041 tgccgaaccg ggctcggcgt gcagggtcag cgcggtgcgg tagatcccct ggtaggcgtc
     8101 gtcccaggcc ggggtgctgg tgcagtgcac gtcggtgaag cccgccgtgt gcagcacgcg
     8161 agtcctgtcg gtgtgccggt ggcgcggtgg caggcgctcg tcgccggggg tgtgcgggtg
     8221 ccagccggtg aggaccagtc ggccgccggg cttgaggatg cgcaggacct ggcgggcggc
     8281 ggcgacgcgg tcgggggcgt actgcagggc gtccagcgac agggcctcgt cgacgcattg
     8341 gctggtcagg gggaggaggg cgaggtcggc cacggcgaag gccgcatcgg ccgcgaacgg
     8401 tacggcccgg tggcgggcct gggcgatcgc gaccggggaa aagtcgatgc cgaccagggt
     8461 cgcgtgcgcg cggccggcga gccacaggcc gggaccgccg cggccacagc ccagatcggc
     8521 caggatctgc cgggggcgca agtcgagttg gcgggcgagg tggtggagca ggtcggcgca
     8581 gaggaaggag aacaggtcga ggtccggcgg caggtccggg tcgaccaggc gcgcgatcgt
     8641 gctgaaggcg ctgccatgtc cctcggttcc ctcggtgccg aagaggcggt cgaactccaa
     8701 cgcactggtg gtctggtggc cggcggtgtc ggccgcgcgg ccggcgggtg gtgtgctcat
     8761 gtcctactcc ccggggcgac cgtgatggtg atctggcgca ggatctggtc agcccgctcg
     8821 tcgacggtgc gcggatcgtg gccggtgacg atgacatggc cgaggcggcc gcggttggac
     8881 gtcgccggac ctacgtccga gccctcggcc gcacgcacgc gtacggcggg gatggtggtg
     8941 gtcaccgctg gcaggccggt gacggcgacc agccgtcccg catggtgagt ggtcaggaac
     9001 cgtacggtgg cgtaaccgcc gggtgcctgt gtgatggtga ccggcctgcc gagggcgatg
     9061 tcccacacgg tgcgccacgg gtcgatgccg agagcgtgct gcatcaggac gccgatgtgc
     9121 ccggcgccga gtcgggcgcc gatctccagg acggtgcacc ggccgtcggg gctgaggacg
     9181 agttcggtgt gggtggcgcc gttgcgtacg ccgactgcgg cgatcgcccg tccggcctgt
     9241 tcgagtaggg cccgctcggc ggccgcgggc aggcgggcgg gcagcgtgtg gcccagttcg
     9301 acgcggtgga tgccgctggt ggtgtgcttg cgggtgatgc acagatgggt ggtgacgtcg
     9361 tgctgggtga tgtactcgac gctgaactca cgtccctgga cgtgttcttg gaccaggatg
     9421 cgctcatcgc gcagcatgcc gtacatcacc ctggccgtcc gggcggcatg ccaggccggc
     9481 tcgagctctt cgggaccggt gaccacggtg acgccggccg atccggcgcc gtcggccggt
     9541 ttgacgacac acgggaagcc gaccgccccg gcctcgtgca ggccccgcag ctcacgcagg
     9601 tccgcgacgg ccttggtgcg gggcatggtg acgtggccgg cttcgaacgc ggttgccatg
     9661 agggccttgt tgcgtgcggc ggcggcgcgt tcgggatcgt tgcccggcag gccgagggcc
     9721 gcgcacgatc gggcggccac ctcggtgagg tactcgttga cggtgagcag ggccttcacg
     9781 ccgatccggc gcccgtagcc ggtgatgtcc gcgacggctt ggccgggccg ggtgaagccg
     9841 gtgacgaggc agccctcgag gagctggcgc agctcgccgg agtagctggc cagggtggcg
     9901 gcgtccgtga cggcgtgcac ggggtggccg gcggcggccg cggtccgggc gagtgcctcg
     9961 gactcggggc cggccgcctc cagcagcatg accggcacgc tcaccggtag tccaccaggc
    10021 cgcccgcgcg gtgcgtgtcg agggtgaagc agtggaatcc gccgccgaag agcctgcggt
    10081 gccggtgctg gaccgggatc acggtgaagc cctcgttctc cagggtcttg atcaggccga
    10141 ggcagtcggc gttgaccagc acccgctgct cgtccaggga cagcacgttg atgtcgatgt
    10201 acgggctggt cagcagcagc tcggagtctg tgtagacggg gaactggccg ggctccggtt
    10261 cgggcggcac aatgaacgtc catgtccgga aggcatccgg gaggatctcg cgcagcccgg
    10321 cgtgccgggc gaggaacact ccgggcttga ggaccaggag catggagtcg atgtggttgt
    10381 cggccatccg gtacacggtg tgcacgcgga agcggccctc cacgtgccgc ttcagccagt
    10441 cgaccgcgag ccggtggttg tcttgcgcga cgttgacgat caggtcctgg cccaggcgca
    10501 gcacctgcgc cccgtcgagc atcatctcca cgcccacgtc gtatgggctg ggctgtgggt
    10561 cggtgatcgg ctcggtcggt ccgcccaggg tggtggctgc ggactgggcg tagctgaggt
    10621 cgaaggaccg gtcggtcagg acggggcggg gcatggtcgt ccagcgggct ccggtgtcga
    10681 agtaggagcg gaagacctgg ctgaggagcc gggtttccag gtagcgggag cggaccgccg
    10741 gcggcgtctc gatgatctcg tcgccgagga cgagggtgtt gtcccgcacg ttgagggctg
    10801 gggtcggggc ggcctgccag cccagcccgg cgatcggtaa ggcgtcggtg ggcagcggca
    10861 gcggccggtg cacggtgatg ccgagcgagg tgagcgtggc ggcgaggttc tcgacgtcct
    10921 cgtggagctc ctccgtgtac cgcttgccga tcttccacgt ctcggcctgt tcgctgccgc
    10981 cggcggccag gcgcggatag gcccagtcgg agcggtagcc gccgatggcc tcgtggaaga
    11041 acaactcgaa ggtgaggtcc cggtcgtgcc ccacgtagtt ctccgcggac cccacgatga
    11101 tctcgctcag cggggtgaag tcgtcgtagc tgttcagcgt gcgcattgcg tcctcgattc
    11161 gtcgtgtcag gcgccggccg ggctgctgtc ggcggccggg agggaaacgt gctggctggt
    11221 cagggcacgg ccgtgccgtg cgtggagcac gacgtggtcg ttgccgagct ggagcgtgcg
    11281 ctgctcgctc cagccggcgt agcggtactc gccgtcgacg acgtgcacca gggcgaagcc
    11341 gcgctcggca tgggtgagga ccaggtcgcc gtcgcgctcg gtgagccgga ccggcacggt
    11401 ggggccttcc agcggggtgt cctggctgaa gtcggtgaac ccggctggca ggttcacggc
    11461 gcgcggcagc ggtgggctcg gccggagggc cgggtcgggc agccggttga agaggacgtc
    11521 ggcgtagccg agcgactcct gccactcggt gggaaacagg gtggcgagtt cccgggtgaa
    11581 cagcgcgtcg atgaccgcgt ggaccctgcg gacggagccg gtgttggcga ccatgtgctc
    11641 gcgggagaag tcgccgtacc agaaggtgcc gggctgccag cggtgttcgg tgccgtccag
    11701 gacgaggacc gcgccggggt gggtggcgat cgggatgtgc aggcgcacca tgcctcgctg
    11761 aagcgcgtat ttggggtcgc ggtgtggctg ggaggcggcg cccgggccga gggcgagcag
    11821 ccgtacggcg ttcagcgggg ccgggatctc gtcaaggatc tcgcggaggt acggcatctg
    11881 gtcgagccag cgggtggcgg cgtagtggtc ggggccgggg ccgcccgggt cggtgcgggt
    11941 cgggtcgccg ccggggctgc gcagcggcag cacgcgccag tcggtcgggg tgtccgggcc
    12001 gatgcgtccg gcggcgtagt gggtgcgctg gcgctgccaa ggatggccgg tgaccgcgga
    12061 gagttcgtgc gcgaggcggt ccgcgtcgaa ggccggggtg aggggggccg ccggcgccgg
    12121 ccgggcgggg gtcgtggtgg tcatctggcg agtgccttcc tggagtcagt ccgccgcgcg
    12181 gtggaggagg tggtggtgaa ccggtcttcg agggcgtgcc agatcgcgtc gcggtcggcc
    12241 gggctggcgt ggacggtgga gaacgtgaac tgcgccccga gggagggatg gtcgacgatg
    12301 ggcatcgaca cgatcacgcc gctgcgggtg gcggggtcgt agccgagacc gagctcggcg
    12361 agcgcgcggt ggaaggtcga gccgtcgggc aaggtccact ccggcggaat gtgggattcg
    12421 gtgacggtgc gctcgggggt ctcgttcgcg tgcacgatgt ggtgggcgaa gacctcgtag
    12481 atgtgccacg agccggagac ctgggcgttg acctcggtga acagcagccg tccgtcgggc
    12541 cccacgatcg cgtcggtgct gatgcggccg cggtagccaa cggaccggta ggtgtgggcg
    12601 aggcgggcgg acccgtcgag cagctgctcc tcgacggccg cggacaggtc gcgcaggggg
    12661 acgctttcgt ggctgaggcg ccggtcggtg tagcgcagtt cgccgcgctc ggtgggctgg
    12721 gtgccggtct cggtgaggtg ctgctcgcag tagaccgtga aggcacccgg gatgaactcc
    12781 tccaggacga cggggaaccg gccgtcggcg gaggcccacg tccagcgctc gcgccagtac
    12841 gcggcggccg ccgcgggaag gtccgtgcgg cccaggtggt ggaggtgacg ggcgcccgcg
    12901 tggccggtgg ccagggtggg atcggtgacg agcagctcgt tgcccacccc ggccccgttg
    12961 tgtgcctgtt tcacgaccac tgccccgctg cgctgcagca gggtcagggt ggcggcggcg
    13021 gcctcgcccg ggtcgcgtac gacggtgccg gctgccaccg gcactccggc cgcggccgcg
    13081 agcgtgcgga acacggcctt gttgttgacg agttcgccgc cgccctgggc aaggaagtcg
    13141 cagccgggca gtttctcggt caggccgagg gcggtggcga agcgggcgac ggaggctgac
    13201 ggccacagtg cccagatctc ccccaccgcg tccgggccgc cgtgcttggc gaggtacgcg
    13261 cgcacctggt cgagggtgtc ggggtgggtg agcatctggg ggtcgagcag gcggccgccg
    13321 taggcgccgg tcggcgccac gaccaggtgc agccggttcg ggtcggtgcc ggtcagcgcg
    13381 gtcgcgtacc gcaggaagtg ggggtccggt ggggcgcaca ggacgaccag gtcgccgttg
    13441 cgcgcacccc acagggcgcg ctgcgtccat gcccgcaggt catggcggtc gcggatggcg
    13501 gggtcgatgt ggttggcgat gatgatcctc aacgcatgct ccaggtcggg aaggtgacga
    13561 ggcgggtcag ggctggaggg tgacgggcag atggtcgaag gcccgcatgg tggcggtgtg
    13621 tcgtcgccgc gcggggccgg ccgggtgcag gaggcccggg tggtcggcga gggcgtcgag
    13681 gagcgcgacc aggacgcgct gggcgagggt ggtgccgagg caggcgtggg tgccccagcc
    13741 gtatccgagg tgccggttcg gcgagcggtc cagcaccagc cggtccgggt gctcgaagtg
    13801 cgcggggtcg cggttggcgg cctggaacag caccgtcacc ttctcgccgc ggtgcaccgt
    13861 cctcccgccg agcaggacgt cggtggcggc gagacggctg gtgccctgga cggggccgtc
    13921 gtagcggacc agttcgtcga cgcccgtggc ccgcagctgc ggcgtctcgc gcagtgcgcg
    13981 ctgggcctgc gggttgcggg ccagcgtgtc gacggcgttg ccgatcgccg cggccagggt
    14041 gctgtatccg ccctggaaca tcacgcgggc cgtgtgcacg acgtaccgtg cgagctccgg
    14101 gccggcgtcg gccgtacggg tacggacgtg gccgagcagc ccggccgggc tgccggtggt
    14161 ggtgaaccag gaggccacca gttcgctcag cttctcccgc gcgagacggc cgggctcgac
    14221 aaggtcgggg ttgaggcctc catccatgct ccgcatgatc gtgtcggata cctgcaccca
    14281 tgcggacagg ggcggcgggg tgaccccgag caggtcggcg atggcgtcca gggcgacggg
    14341 ctgggcgagt tcacgcatca cgtcccacgc cggctgcgag gcaagaacct ccagccgggc
    14401 cgcgatgtcg cgtcgggtcc gttcctgcag cacgggcagg tcctgcgcgt gcagcgaggt
    14461 catgaaggcc gaccgcacgg cggcctggtg gggcgggtcg aggacctgca cgctcagcga
    14521 ggcctccggc accgtgcggc ccagccgcct ggggtcacgg gcgaaggcct cgtggtcccg
    14581 cagaacgcgt acgcagtcgt cgtagccggt gaccagccag ctttccatgg tgtcgtgcca
    14641 caccaggggc gcctgcgcgc gcagcgccgc gagcacggga tacgggtcgg cgagggtggc
    14701 ttcgtccagc gggtcgtacc gcaccgggca ggtgggcgtc acggccacgg tggtctcctt
    14761 cacgcggtag aaggggcgga ccggtcccgg ccaccgacga gacgtcggcg gccgggaccg
    14821 gaacgggttg cggagcacga tgtacatcag tggtcgtacg tcatggcgga cccccctttc
    14881 ggcctcgggc gggacagccg cggtgtgctg cgacatcatg agaatgggct caactgttcg
    14941 agttcgtcga ccagttgagg ggggtcccgt gggggtcccg ccttcgtgaa ggagtcacca
    15001 gtcctgtgcg ctgagtgatt ggatggagac gtggaagaga ccaccggtca cccgttggtt
    15061 gtggcgcgtc atgcggccgg caagacgatg gaggagttcg tctccggcat ccatgcctcc
    15121 gccgctcggc ggaatctgcg ttcaggcatc gacgaagcac gggtgcgcaa atggcagcgc
    15181 ggcgtccaac ccagcgagga atcccagatc tacatcgccg aagcactcgg ctggcctgcg
    15241 gacatcgtcc gcgccgacga ctggccgaac tggctgccgc tcaccgccaa cggggtagtc
    15301 cccctcggcc cccacagctc cgtgcccgcc ctgagagagg cccagcgaac agcgatggaa
    15361 cgccgcacct tcctgacgat ctccggcgcc gccctgtccg ccctggccgc ggactgggcg
    15421 ggcggccccg cagacgcgct cgcccaagcc cacgacggta aacccatcgg cgaagacctc
    15481 gtcgccttct tagagaactc cacccgacac ctcgccggcc tgtccaccga gcagcgacag
    15541 cacacccccg cgctactgga cgcccacctc gccacggtga ccgaactgct cgaaaacggc
    15601 cgctacacgc ccgccctcgg gctgcgcctg cacaccctgg cggcctccct ctcccagacc
    15661 gtcgcctggc acgccttcga cctgggccgc cacacacatg cgagccagag ctgggtcgca
    15721 ggcctgcaca acgcccacgc cgcaggggac catgacatgg gcgccggcct cctgggcgat
    15781 ctcgcctacc aggccgcctg gcgccgcgat cacatcactg cggccagcat cctcggccac
    15841 gcactgaccc gcgcccagaa ccccgccgcc cgctgcctgc tccagctccg cctcgcccgc
    15901 accctcgcag cacgcggcga ccgcagcgaa cgacgcgccg tgctgcgcgc cctcgccgcg
    15961 gccgagaaac acctcaacga cgctggcacc gaacggcccg cctggtgcgc atgggtgggc
    16021 gcagcggatc tcgcggtgga ctccggccag gccctcctgg acctcggcga cactgcccgc
    16081 gcccaccagc tcatcaccga aggcgaacgc ctgctgccca cagctaggga caagacccgc
    16141 ggcgtgttcc tcgcctaccg cgccgcgagc tacctcgacc tgaaggaacc cgaggccgct
    16201 gcggccgccg ccacccagtc cctactgctg gcccgtcgca tcggggcacc ccgctgcgta
    16261 cagctcgtcg acgacctgct cccccgcttc cagccctacg cccgtgccca aggcgttccg
    16321 gaactcctcc agctcacagc cgcatagacc gttctcctcc aggtcgggaa catcgctcgc
    16381 gtccggggat cgggagcccg tcgctgagga gctgtgttcg tacccgcgtc cgcggggacg
    16441 gtcttgcctg ccgtcccacc acatggagaa cagcatgagc gagttcgctg gcgccaccta
    16501 ccggcccggc atccccgagg ctgccgtccg tctcgtcagc cagacggtcg ctgccaagca
    16561 gcacccggtc ctcctcgacc ttggatcggg cacagggcaa gtgcccgctg ccctgctcga
    16621 ggccttcgct gagattgacg tcgtcgaaag ggaccccggc atgcttgcgg aggccgagac
    16681 cagccggccg tgctgtcgct gctggacggc tgcacggcca aggacgccac tttcgttgtc
    16741 atgggggacg acagcctctg gacggcccgc tcggcatgga cggacgccca gcggtccctg
    16801 atccaggagt acaccggcag cgaccgccgg gcgggcaaag acaggaccta cgctgatggc
    16861 gattcttgaa atcggccggg gatgctcctc acctcactcg ctccgctgtt caaagatgtg
    16921 aggagcttca gcgagcgtcg tgcccggtct tcggccggcg cccgctaatg gaggtgcggg
    16981 ccgggttgag ccgtcaagga cgcctgcggc ggccctgcga agtggggtcg cccatcctgg
    17041 actgctcgcc ccgctcctgg acttgggtgg catcgggcag ccccctccac tgtggcgtcc
    17101 ggcccgggtc tgacgtacgt cgccgcccgc tgcgacgaag gcttcggcgt ccggccgggg
    17161 cctgcttggg tgtcagcgga ttcagggctg acgcgccgcc tcgtgcagtc ggtcacgtgc
    17221 ggccctcagc aagccctgcg accactccgc acgggtgact ccctcgggca gtctggtcaa
    17281 ctcggcgtgg ctggcgccca gcgcgcgggc ggtcgcctcc accgcgagac cctgcataag
    17341 atcgtcgttg tactcaccgc ggccttcctc ggcgagcttc agcagggcgc ggaggagttc
    17401 ggcgtcgaac ccgtcgtgca ggatccaccc agcccccgag accgcggcca tgaacacgtc
    17461 gtcatccagg tcccactcgg gggatcccag caactcgagg atctgcttcc tgtacttcgc
    17521 tcccactctc cagtgcgcgg tgagcacctg cacggcgagt gccgagacct cgggatcctc
    17581 ggggtagatc agatacgcgg cgatcagcgg ctcgtatgcc ggaccgcccg cacgggccac
    17641 cgcatacagc cgctggtaga gctcccggcc ggcccggcac tcggtgacgg cttgagcgat
    17701 ctgtttcacc tcctgcggcg ggatggtgcc gtccttcgcc cgtgcgatca gctgccgcac
    17761 atatgcatca tgcgccactg tcatgctcca ctcacttgat tctggggacg aactgctcgg
    17821 agaagtccag cattctgctg gcccgcccca ggtcggcgac gagaaggtct cgcatggcgc
    17881 cactcgtccc aggatgggcc agcttcctgt tgattgcgga aggggcgcat cctcagcaac
    17941 ggcgactatg cggctcgata gaggccgcgt tttactcgca caaccttccc catcttcagg
    18001 agcccatcga gatacacgga ggcgccgtct ggcttcagga ccgaacccgc cgcagtcacg
    18061 gtgtccgcga tctgccccag cgtcatgggt tctgaggact gggcgagggc agcaacgatg
    18121 gcttccgcct tcgtcatccc ctggacgttc agctccgggg ccttgacgat cagcccctcc
    18181 agcgtcgctt ccttggcccg cagggccgcg atttgagctt cgagccgctg agattcgagc
    18241 tcggcggcag ccagctcaac cctcacctgc ttcaggtcat cctcgagtgg gttcatacat
    18301 gcaaccttac aggaatctaa gaatcattcc tagctgccta agattatttc ttagagcttg
    18361 ctagatcgtc ggtcgaggcg gcgacaaggc tccgccaatc cctgcggtgg tagttgagtg
    18421 acgtcccgtc ccaggtcaga tgccgtatga gtggggagac gcgtggagca ggtatggggt
    18481 cacccccgag cagggggtgg ggattttcaa ggagcgtcat caacgcggcc ctcggccgcc
    18541 cctaccggga aaacctcgcc gagtccgtct tcgccgctga gcttgactct gtcggtgatc
    18601 ttggagtttg ccggtgcggc agcatgatcg gcgggcatgc tcgggtcgtt ccgccgaccg
    18661 atgcagttgt cgaggtgtct gttgtccctt cgcccccgtt ccggtgagca agtcccgtct
    18721 ctgaccgtgc aggttgcgcg ggcgagcaac ccgggtggta cgacggcgat atgggtgcgt
    18781 gaccggctgg acgggctgtg gtgcgacgag gacttcgccg actggtaccc gcgggacggg
    18841 cggccgggtc tctcgcctgc tcaactggcc accgtctgtg tgctgcagtt cctgctgggt
    18901 ctgtcggacc ggcaggcggc cgaggcggtc cgctgccgca tcgacttcaa gtacgcgatg
    18961 gccatggagc tggacgatcc cggcttccat cacagcgtgc tggccgactt ccgcgaccgt
    19021 ctcgctgaag gcgaccgtgc cgaccgtctc ctggacctcg cgctggctcg tctcaaggag
    19081 gccggactgg tgcgcgagcg caccacttag cgcaccgact ccacccacgt tctggccgcg
    19141 gtgcgcgacc tgacccgcct ggagctgatc accgaggccg tccgcgccgc actcgaagaa
    19201 gtcgccggca catctcctca cctgctcgac gagttggtcg atgaggactg ggggctccgc
    19261 tacggccgac cggtccgcct gggcaagaac cccacccggc ccaagaccag gatcctcgcc
    19321 acgggaaacg acgccgtccg ggtcctggaa cacctctacc ggcacgggac agaccacacg
    19381 ttcggccctc gcatccaggc cctgcggcag atcatggtgc agaactatca ccatgacggc
    19441 gcaggacacc tgcgctggcg caccgccgag acggaaggcg accccgggct gccgccctcg
    19501 tccctggcgg tcgtctcccc ctacgacacc tcggcccgct atgcacggca cggacacatc
    19561 atcagctgga aggggttctc cgctcacctg accgagacct gtgctcccga cggccccaac
    19621 gtgatcacgg acgtggccac caccgcggcc accacccacg acagccaggt cctgcccggc
    19681 atccacaccc gcctcgcccg ccgcggactg ctgcccgccg agcacctggt cgacgccggc
    19741 tacacctccc tgccccacct ggaacaagcc acccgtgaac accaggtcac cgtctccgga
    19801 ccgctccgga gcgaccccac ccgtcagcac cgccggaacg agggcttcgc ccgggacgac
    19861 ttccacatcg actacgaccg tcagcaggtc acctgcctcc agggacaggg ggttggcacg
    19921 gcccctaccc gacctcctct cccaccgcgg ccccgctgat cgtggctagg ttcgccaaga
    19981 gccagtgccg cccctgcccg gcccgcaccc agtgcaccag caccgccgac agcgcccgca
    20041 ccgtgggctt tcccccgcga gagccccgcg acctgcaact ccgcgtccgc gccgagcaac
    20101 agacactcga gtggaagact cgatatgcgg tccgctccgg agtggagggc acggtcaacg
    20161 agttcgccca cggacatggc atgcgacgct gccgttacag aggccaggga aaggcccaca
    20221 tccagcacgt cctgacggcc atcgcagtca acatcgagcg cctcagcgaa ctgccaccga
    20281 ccgaagaaac acccacgccc cgccggccaa ccgcccttca gaactacctc gaccagcgtg
    20341 agatacgccg gctgaagtcc tggcgaaccc tgggcagcta acctcggcac tccaagatca
    20401 ccgacagagt caagctcaga agctgtgtca catcctcttt tcgcaggtca cggggtcgtg
    20461 acgcgcggca gtgatcccgc ttgacgttgg gttgggcatc gatgggcagg cgcccgaacg
    20521 gcaatggaag gatcttcagg cggctgcgag aggctgctca actggctagg agagcgatca
    20581 cggccatcat gggcggcagg gaaacggagc tcaccagaga tgaaccccgg tgaccttctg
    20641 cataccttct ccatcgatct cgtcgccgaa cggcacggtg acctggtgac gcctgcgcgt
    20701 caccaccagg tcaccgggtt gttcgtggct acgggcgaag ggcgataaaa ttacccaaat
    20761 cggtggcttg gcttccgggc ccaggctgcc gctcgacctg tgcgagggag cggcacggtg
    20821 gcgaggtctc ctcaggaacg cggagtcccg cacagcgccg gtgcgcggga caggttgctg
    20881 cccgtgctgc ctgctctgct gctgttcggc ggcctgctct tcggcctctt cacaccccgc
    20941 gatgtgaggc cggatgcctt cctcgccacg gccatggttt ctgccgccgc gctgctgtcc
    21001 ctgcggggga ccgtgctcac cggagtgggc gcgtgcgcca tctttgtctg cctgatggtg
    21061 gacttcaatg ggctgcggga tgcgaccgcc tactctgagc tggccaccct cgtggcgatt
    21121 gcggcattcg ccgtcttctt caaccgtctg ctgggccgac gtgcccatca gctggttcag
    21181 gtccgctcgg tggccgagac cgcccagctg gcggtgctgc atccggtacc gagacacctc
    21241 gggcacgtca cgctcgagag cctctacctg gccgccgcgg cggaagcccg gatcggcggc
    21301 gacctgtacg aggcgatacg caccccgcac ggcgtacggc tgctcatcgg cgacgtacgc
    21361 ggcaagggcc tgctcgcggt gcggacggcc gcgacgctgc tcagcgcctt ccgcgaggcc
    21421 gcccacgacg cgcccgacct gccccacctc gcgtgccgcc tggagacgag catgagccgc
    21481 cacgcgtccc agtacccggg ggtcccgggc tcggagatcg ctgaacgctt catcactgcg
    21541 ctcctcgccg agatcccgga cgacgaaccg gtcgtccgga ccgtcacctg cggccacccg
    21601 cccccgctac tgctgcaccg cggcgaggtc cgggaactgc agcccgccgc tccctcgccg
    21661 ccgctcaacc tgggcatgct gatgagcgac gggtaccacg tcgacctcgc ccccttccac
    21721 cccggagacc agctcctgct gtacaccgac ggagtcactg agacacgcga ccgctccggc
    21781 accttctacc ccctcgccga acgcatccgc tcatggagcg gcgaggcgcc ccaccaactc
    21841 ctcgaccatc tccaccgcga cctgatcacc tacagcggcg gcgagctcca cgacgacatc
    21901 gctgccctcg tcgcccggcg gcgcccgaac cgctgagcct gagatgaggc gctgacctgc
    21961 gcaggtttca ggtgccggaa ctcgttcgag gtgcctgaag ccggtgtctt gggcgacggc
    22021 cttgccctcg gcgacgacgt cggtcgtacg gtggcctgca tgggcagggg cgcggtgccc
    22081 cggccgaggc tggtcgtggt cacggacgac gatgccgggc cccggttgtg ccgtgggtgc
    22141 ggcatccgtt actgccgttc ggtcgcccgt ccatcgacga ccagccgaac ggcagaccgg
    22201 attatgatca cgtctcacaa tgccatgagc tgcagaaaga ggatgtgaca cagcttctga
    22261 gcttgtggtt tatccagtgc ggcgtggttt ggtgccgatt ttgtgatgtg tgggtcggcg
    22321 gtggagttcg ccggtgacga ggagcaggcc gacgtcgtag cgttcggcgg ggtggcggtt
    22381 cttcgagccg ggtgggcgtc cggggccggg ccgggagggt ttcggcactg cggccggcgt
    22441 cgggatcttg gcacgcaggt gtcggaaccc gcgccggacc cgtgcggggg tgagcctgtt
    22501 cgaagggacg gggcgttccc aggggcggcg taggtcgatg gccagggggc gggcgaggcg
    22561 gagctgggtg taagcggcga tgatcagcca ggtccagttg tccgccgcct cggggtcgcg
    22621 cagtttcggg gcggtccagc cgagggtctg tttgatcatt ctgaagaagt gctcgatgtc
    22681 gaatcgtctg aggaacgcct gccagacctg gtcggtctcc gccggggtgg ctgtgggctg
    22741 tgaccaccaa agccacaggg gcttggggtc accgccgttg ggcaggtggt cgacttgaag
    22801 gcggatgacg gtgccctcga tgacagggag cctgccgggg tggttccgcc aggcggcacg
    22861 ttgttgcagt tcagggtgga gccggtacca gctctgggcg tgggcggtgc cgtagcgggt
    22921 ggtgagggtc ttcgtctccg cgtcgggggt gtcccaggtc ctggggtcct tgaagatgaa
    22981 ctcgccgccg tgccggggcg ggtggccgcc gcggggatgg gcccggtagt actcctcgcg
    23041 ggagggcgcc ggacggcgca tgacccggtc cgagcgcagg cgcccgagga gttcgacggg
    23101 caggtcggac agaagccagg ccagacgcat cacgtcgtag ccggcgtcga gcacgatcca
    23161 gatgagcggg tcgcccacgt tccactggcc cgcctcgacc agacgcctga ccaggtccct
    23221 cacttgggcg gcggtcacgg ccgcgaggtc gtcgcccggc cgcagccgta cggcgtccag
    23281 gggcgcggtc caggaggagc ggcccgtctc cagggcgacg atccaggaga cgggccagcc
    23341 cgggatcatc aggtgcttgt tctcgccgcg gccgtaggtg tgacagaagg agcgggcgtc
    23401 gctggtggcg gcgtcgggcc gcagccacgg tgagacgtcc acggccagga ccagacggcc
    23461 gtcggctgac cgaggcagcg gcatcgaggc caggacccgc cgcaaccggg cgacctcgat
    23521 tcggccccgg tt
//
