LOCUS       NZ_CP041405            21627 bp    DNA     circular CON 07-APR-2024
DEFINITION  Paenibacillus thiaminolyticus strain NRRL B-4156 chromosome.
ACCESSION   NZ_CP041405
VERSION     NZ_CP041405.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus thiaminolyticus
  ORGANISM  Paenibacillus thiaminolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Paenibacillus thiaminolyticus NRRL B-4156
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2019) Institute of Personalized Medicine, Penn
            State College of Medicine, 500 University Dr, Hershey, PA 17033, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2018
            Assembly Method :: Canu v. 08/2018; Pilon v. 08/2018
            Assembly Name                     :: PSU_Pthia_1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007066085.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 14:58:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,886
            CDSs (total)                      :: 5,776
            Genes (coding)                    :: 5,673
            CDSs (with protein)               :: 5,673
            Genes (RNA)                       :: 110
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 52 of 103
            Pseudo Genes (incomplete)         :: 68 of 103
            Pseudo Genes (internal stop)      :: 17 of 103
            Pseudo Genes (multiple problems)  :: 28 of 103
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:43:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4757310
            Orig. end                         :: 4778937
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041405.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Schiff/Broach Lab 500
            University Drive Hershey, PA 17033
            Chromosome not circularized.
FEATURES             Location/Qualifiers
     region          1..21627
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="12"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21627
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21627
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11627](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11627)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            complement(288..920)
                     /db_xref="GeneID:76998463"
                     /locus_tag="FLT43_RS21105"
                     /old_locus_tag="FLT43_21105"
     CDS             complement(288..920)
                     /codon_start=1
                     /db_xref="GeneID:76998463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678245.1"
                     /locus_tag="FLT43_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21105"
                     /product="oligopeptidase"
                     /protein_id="WP_087443072.1"
                     /transl_table=11
                     /translation="MKVPHRNGRPGIPDPVELMSVPRMRGPHAMHSASPLARERAARNQ
                     ARARPAGIRMNTRSFNGPPPGLPAGYPELSGYTPYQEAPIVPFNAVAETPIEVAAQPEK
                     KLLGNFSMGDLKSMIDKLGGIEGIVDTMGKVQKIMSSVQQIMPVAKMFMGTLLPGKGGG
                     KKLSTADGGDDAPRRRRRYSSGSPRSGSGNRRKSTASRTGSAPRRKK"
     misc_feature    complement(933..946)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 19.52"
                     /tool="antismash"
     misc_feature    1070..1089
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.65"
                     /tool="antismash"
     gene            1225..1515
                     /db_xref="GeneID:76998464"
                     /locus_tag="FLT43_RS21110"
                     /old_locus_tag="FLT43_21110"
     CDS             1225..1515
                     /codon_start=1
                     /db_xref="GeneID:76998464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009592310.1"
                     /locus_tag="FLT43_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21110"
                     /product="YerC/YecD family TrpR-related protein"
                     /protein_id="WP_006678246.1"
                     /transl_table=11
                     /translation="MQLKKLNDKSIDQLFEAILTLESLEECYIFFDDLCTVNEIQSLSQ
                     RLEVARMLGKGCTYNQIEAETGASTATISRVKRCLNYGNDGYKMTLERLGR"
     gene            1591..2376
                     /db_xref="GeneID:76998465"
                     /locus_tag="FLT43_RS21115"
                     /old_locus_tag="FLT43_21115"
     CDS             1591..2376
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019419967.1"
                     /locus_tag="FLT43_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21115"
                     /product="CbiX/SirB N-terminal domain-containing protein"
                     /protein_id="WP_244951362.1"
                     /transl_table=11
                     /translation="MAQAAWPEGVPIASSFLDCVPGRTIQDGIDELEAQGVDAIGVIPL
                     FISGGSTHVDEIAYALGVTSAPLADTKLPPFRLRAQVRYGRPLDGAALFAAACGGDGPG
                     GDGPAGEPEAGTVLLHMVEDRLRGLGAGAGDAALLVAHGSRHEPFAGRWHASLRRLARQ
                     LVQRSACAAASHALLCCEDIAAAARKLQQALAVMPADAGPACWRATARWRHARRLPRPR
                     PGGTRPPGAARGGGAGVPEHRLFYGAGYSRAAGRCAGAL"
     gene            2303..2470
                     /db_xref="GeneID:77000231"
                     /locus_tag="FLT43_RS30275"
                     /old_locus_tag="FLT43_21120"
     CDS             2303..2470
                     /codon_start=1
                     /db_xref="GeneID:77000231"
                     /inference="COORDINATES: protein motif:HMM:NF014016.4"
                     /locus_tag="FLT43_RS30275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21120"
                     /product="CbiX/SirB N-terminal domain-containing protein"
                     /protein_id="WP_244951363.1"
                     /transl_table=11
                     /translation="MFLSTGYFTARVIPERLGDVPALYDGRPLLPHPALVEWLSREGER
                     LLAGMKAEDG"
     misc_feature    2597..2611
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.52"
                     /tool="antismash"
     gene            2688..3602
                     /db_xref="GeneID:76998466"
                     /locus_tag="FLT43_RS21125"
                     /old_locus_tag="FLT43_21125"
     CDS             2688..3602
                     /EC_number="2.7.1.107"
                     /GO_function="GO:0003951 - NAD+ kinase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679189.1"
                     /locus_tag="FLT43_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21125"
                     /product="diacylglycerol kinase"
                     /protein_id="WP_174818228.1"
                     /transl_table=11
                     /translation="MIKKARLIYNPTSGREEGKKRLADILHMLDAAGIEATAHATDGAG
                     DATASAADAIDRGYDMIIAAGGDGTLNEVINGMAGKPSRPPLGIIPLGTTNDFARALGI
                     PRHWEDACSIITRQKTRVIDLGQANDTYFINIAGGGSLTELTYEVPSKLKTMIGQLAYY
                     MKGLEKMTSLRPTELRIEVDGHGVFHEEFMLFLIANTNSVGGFEKLAPGARIDDGLFDV
                     IMLKKCNLAEFIRVAGMALRGDHILDPLIIHVQSKRVTVTSPDTVQLNLDGEYGGLLPG
                     TFQVLPSHLRIFADVPEAQPEQG"
     misc_feature    complement(4103..4117)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 20.32"
                     /tool="antismash"
     misc_feature    complement(4204..4220)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.97"
                     /tool="antismash"
     misc_feature    4204..4220
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.42"
                     /tool="antismash"
     gene            4581..6164
                     /db_xref="GeneID:76998467"
                     /gene="rlmD"
                     /locus_tag="FLT43_RS21130"
                     /old_locus_tag="FLT43_21130"
     CDS             4581..6164
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998467"
                     /gene="rlmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679190.1"
                     /locus_tag="FLT43_RS21130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21130"
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="WP_087443074.1"
                     /transl_table=11
                     /translation="MTGKKLGNGAERRKRRGTAAAVRARAVGAKSAEANSAEARTAEGS
                     TAKKRGQAGQKSASAPVSKNDEVVLDIIGLTHDGEGVGRADGFTLFVSGALPGEQVRAL
                     VLKVKKQYGYAKVLERLIDSAHRVELEHPVNAYGGCQLQHLEYGEQLRWKRQHVVDVLE
                     RIGKFQVEHGAETGDADGQPPIKVLPVIGMEHPWRYRNKSQMPIGADPRTGELIGGYFA
                     KASHRIIDTDVSLLQHERNDEAMRAVKRIARKYGIAPYNEETHTGLLRHAIMRVGFRTD
                     EQMITLVTNGEKLPHEAEIVADLVEALPQLTSICQNINTKRTNVIMGEKTRVLWGSEYI
                     TDYIGDIAFKISARSFYQVNPVQTEVLYDKAVEYAGLTGNETVIDAYCGIGTISLFLAQ
                     RAKRVLGVEIVEEAIADARRNAELNGVTNAEFAVGAAEDVIPRWKEQGVTPDVIVVDPP
                     RKGCDTALLDTMLAMRPERIVYVSCNPSTLARDVRVLADGGYRVLEVQPVDMFPQTTHV
                     ECCSLLVRND"
     gene            complement(6330..6860)
                     /db_xref="GeneID:76998468"
                     /locus_tag="FLT43_RS21135"
                     /old_locus_tag="FLT43_21135"
     CDS             complement(6330..6860)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998468"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006677820.1"
                     /locus_tag="FLT43_RS21135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21135"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_087443075.1"
                     /transl_table=11
                     /translation="MRKALLIIDMQVMPFVWKDYGGKSLYQEENLLENTRRLIDKARKG
                     NSPVFYIMFTEPHGSLRSENQPLWQVHEQIVPLAHDHIIIKHYADSFLDSELHPRLRDQ
                     GIDTLVICGVQTEYCVDTTVKSGYSRGYKVELAEDCHSTYDSDGLTAEQIINHHNSILA
                     QFATMVRSSEVQF"
     gene            complement(6862..7524)
                     /db_xref="GeneID:76998469"
                     /locus_tag="FLT43_RS21140"
                     /old_locus_tag="FLT43_21140"
     CDS             complement(6862..7524)
                     /codon_start=1
                     /db_xref="GeneID:76998469"
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006677821.1"
                     /locus_tag="FLT43_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21140"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_244194237.1"
                     /transl_table=11
                     /translation="MKGENILDTLKLQEADNIDCIKVGRLIQSLRKEKRMTQKELALLM
                     NISDKTISKWERGLGCPDVSLLGELSNILGVNIEKILSGDLNPNEQDGGNMKNVKFYAC
                     QSCGNIMTSTGATSISCCGRLLEPLLSKAENDEHEITVHEIEEDYFVTIKHEMSRDHYI
                     SFVAYISYDRVMLIKLYPEQLAEVRFPKMYGGTLYTYCNRHGLWKYEKKKLGSRRVT"
     gene            7832..8215
                     /db_xref="GeneID:76998470"
                     /locus_tag="FLT43_RS21145"
                     /old_locus_tag="FLT43_21145"
     CDS             7832..8215
                     /codon_start=1
                     /db_xref="GeneID:76998470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007722957.1"
                     /locus_tag="FLT43_RS21145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21145"
                     /product="hypothetical protein"
                     /protein_id="WP_087443076.1"
                     /transl_table=11
                     /translation="MKFYRYVLSIPPLDWECCFLSIEEYKQNFANKYNQNIEYYMQVIG
                     DCQQHLVDVDNLAVVTYKDLCASVHSAELRCPAMIFSIPSGDQRGSALFCIMYKLENDG
                     DTFIYSPIPLVHLEQDQAGEIEL"
     gene            8500..8754
                     /db_xref="GeneID:76998471"
                     /locus_tag="FLT43_RS21150"
                     /old_locus_tag="FLT43_21150"
     CDS             8500..8754
                     /codon_start=1
                     /db_xref="GeneID:76998471"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FLT43_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FLT43_21150"
                     /product="hypothetical protein"
                     /protein_id="WP_087443077.1"
                     /transl_table=11
                     /translation="MKDLKILKERKECIFFKRVKMIAVMDGSEGMHRLPFDDNERISIF
                     APKHFEDRLSKDRYPDCSILTMKHLKQKRVNLMPLPIMI"
     misc_feature    complement(8828..8843)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.76"
                     /tool="antismash"
     gene            8828..9916
                     /db_xref="GeneID:76998472"
                     /locus_tag="FLT43_RS21155"
                     /old_locus_tag="FLT43_21155"
     CDS             8828..9916
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998472"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679200.1"
                     /locus_tag="FLT43_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21155"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_087443078.1"
                     /transl_table=11
                     /translation="MKKFLKIFSITILVIVIVSIVALLLFGRNNHSNLSGSVSDKIDQY
                     LTNEKFQGTVLIAKEGEVLFTKGYGLAATDLPNSPSTLYQIASLSKTFTAVAVMQLVEK
                     ELLNLDNPISQYFPDFPNGESITIGHLLSHSSGIPDYLKANFEFDYSKEWNPNDIVKTV
                     SDSELEFTPGKSFSYSNTGYVMLGLIVEKVSGQSYANYIEEHIFEPSNMFNSMFTVSAG
                     IPKAEGHVGGKAGPLMHNSAAYAAGDIISTVEDLERFDRALRNNLLISKETSELMSMTH
                     AKKFPYQYGYGWYTQDVMGKKAVGHSGGYPSGFRHYVTRLHDEELTVIVLSNEMTVNSK
                     RINRNLTSIVLQEPIWIWEEKL"
     gene            complement(10001..11380)
                     /db_xref="GeneID:76998473"
                     /gene="scfB"
                     /locus_tag="FLT43_RS21160"
                     /old_locus_tag="FLT43_21160"
     CDS             complement(10001..11380)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998473"
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679203.1"
                     /locus_tag="FLT43_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21160"
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_087443079.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.5e-31,
                     bitscore: 105.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 2.8e-74, bitscore:
                     248.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.2e-12, bitscore: 44.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.5e-17, bitscore:
                     62.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHHYQLNGYNIVIDTYSGSVHVVDDLAYEIIALYEHAAPEQILM
                     RMKEKHYSEESIRETISEVEELISNGQLFTEDAYEELSIDLQKRKTYVKALCLNVAHTC
                     NLSCEYCFASQGKYNGDRAIMSLEVGQRAIDYLLEHSGHHRNLDIDFFGGEPLMAWKVV
                     KQIVAYARSKEKEWKKKFRFTFTTNGMLLNDEITEFLNQEMYNVVLSLDGRKEVHDRLR
                     TTVTGKGSYDSIVPKFQEFIQKRGDQEYYVRGTYTRNNVDFTNDIFHIADLGFDKISME
                     PVICDPREPYALTEKDLPEIYNQYEILAKEMIARSEQGRGFTFYHYMLDLSEGPCIQKR
                     ITGCGSGTEYLAVTPWGELFPCHQFVGDEAYSMGNIWDGITQPELQCQFTESNCYTKPE
                     CKDCWAKLYCSGGCPANALHATGSINGTYEFSCDVFRKRIECSMMAKVAESIRAMEENQ
                     M"
     aSDomain        complement(11084..11380)
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FLT43_RS21160_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="1.70E-33"
                     /identifier="RREFam024.1"
                     /label="FLT43_RS21160"
                     /locus_tag="FLT43_RS21160"
                     /protein_end="99"
                     /protein_start="0"
                     /score="105.8"
                     /tool="antismash"
                     /translation="MIHHYQLNGYNIVIDTYSGSVHVVDDLAYEIIALYEHAAPEQILM
                     RMKEKHYSEESIRETISEVEELISNGQLFTEDAYEELSIDLQKRKTYVKALCLN"
     gene            complement(11478..11627)
                     /db_xref="GeneID:76998474"
                     /gene="scfA"
                     /locus_tag="FLT43_RS21165"
                     /old_locus_tag="FLT43_21165"
     CDS             complement(11478..11627)
                     /codon_start=1
                     /db_xref="GeneID:76998474"
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016113838.1"
                     /locus_tag="FLT43_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21165"
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_076321126.1"
                     /sec_met_domain="TIGR03973 (E-value: 1.4e-22, bitscore:
                     77.7, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.2e-22, bitscore: 78.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVTLSTRKLMDTAKHGGCGACQTSCQSACKTSCGVANQRCEN
                     AMNK"
     misc_feature    11874..11883
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    11941..11957
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.32"
                     /tool="antismash"
     gene            12146..13450
                     /db_xref="GeneID:76998475"
                     /locus_tag="FLT43_RS21170"
                     /old_locus_tag="FLT43_21170"
     CDS             12146..13450
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998475"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="FLT43_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21170"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_087443080.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.9e-49, bitscore:
                     165.3, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKFLSSVLAAILLMATLVTGVAFGSPDQGYSGDYIEGQLVVSVE
                     EPFMDSIQSVDELLMEAESLTESGFTIADSLFGQDAGSFSVQSLDSDVRATAIEKMGLV
                     YLVEYSVEDYNSIDSAKITLEETLDNLGFNVRYVTENRKMYALETATVQDVSPQDIHNN
                     QRWHYDMIKVPQAWEITTGSSSVRIGVLDTGIDSNHPNLKNLVNTSLGSSFVGGTTNDG
                     NGHGTHVAGTIASYGSVSGVMQNATLIPIKVLNDSGSGSLYGVQQGIVYAANVRADVIN
                     MSLGGGGYDQGMDEAIQTAVGLGTIVVAAAGNDGLPKISYPAAYSGSIAVGSVTSSRTR
                     SSFSNYGPGLDVMAPGSNIYSTYKNGQYATLSGTSMSTPHVTGVLGLMRSVNPNLTSAE
                     AEEILKNTAQPAGSSDQYGHGIVDAHAAVLAASQR"
     gene            13650..13760
                     /db_xref="GeneID:89363032"
                     /locus_tag="FLT43_RS30670"
                     /old_locus_tag="FLT43_21175"
     CDS             13650..13760
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:89363032"
                     /inference="COORDINATES: protein motif:HMM:NF014853.4"
                     /locus_tag="FLT43_RS30670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21175"
                     /product="carbohydrate-binding protein"
                     /protein_id="WP_340162473.1"
                     /transl_table=11
                     /translation="MGDEATYGGATYQCLQEHISMAGWEPLNVPALWLEK"
     gene            14153..14395
                     /db_xref="GeneID:76998476"
                     /locus_tag="FLT43_RS21180"
                     /old_locus_tag="FLT43_21180"
     CDS             14153..14395
                     /codon_start=1
                     /db_xref="GeneID:76998476"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FLT43_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FLT43_21180"
                     /product="hypothetical protein"
                     /protein_id="WP_087443081.1"
                     /transl_table=11
                     /translation="MKKYEKAIFYKQKEVESAADARDKASTILDITALHILNNGYIQAF
                     ESAQSWERLLTQFDSWQYTGLGRMMSECWFDFIKN"
     misc_feature    14174..14187
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.57"
                     /tool="antismash"
     gene            14479..14883
                     /db_xref="GeneID:76998477"
                     /locus_tag="FLT43_RS21185"
                     /old_locus_tag="FLT43_21185"
     CDS             14479..14883
                     /codon_start=1
                     /db_xref="GeneID:76998477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018756298.1"
                     /locus_tag="FLT43_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21185"
                     /product="DUF1259 domain-containing protein"
                     /protein_id="WP_087443082.1"
                     /transl_table=11
                     /translation="MPNSGSLCAKFSRIIGGQPGFAGGKCVSTINRKRIRATILGKRFS
                     VTSSFSFESLDERTGKALCVGRAAFLEKEVNPFITAIRKQGIKVTSVRNEWLFERPLLM
                     YVNIEAVEKPLVFARKVRRALDAIHEGFKL"
     gene            15053..17410
                     /db_xref="GeneID:76998478"
                     /locus_tag="FLT43_RS21190"
                     /old_locus_tag="FLT43_21190"
     CDS             15053..17410
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998478"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679325.1"
                     /locus_tag="FLT43_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21190"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_087443083.1"
                     /transl_table=11
                     /translation="MPNAATNNNYEISMENIRSMPPTSYFGTKILFVISGSLTVNCTAR
                     DYKLQAHDILILNRNDRHEIASQEDNIVIVLSLTAQFFAQHDKSYFSYHFDCFSREMDP
                     GREQMVALLRRYVAEIMIAYSRTGALPNLELQSSLFQMMLLLTRFFKTEAPVREGSSHD
                     DERIMRIIQEIEQRYDEPITLNEIAQKEYLSVSYLSRYFKKMTGFGFVQYVNLVRLKHS
                     LDDLLHSTDSLSHIALKHGFASSKHFNAVFKAAYGMSPAQYRKEHSEHQDDVQPAANHA
                     SEPRTVLQSPDILAKLAQYIETGEQISDISEAVFENRQIELDPTRQEEVAASTHVLFIG
                     QLKELLNENVKEQVLMAQQELRIRYIGIRNLIFGKTLLPEVETDELVATSTPFMNSDLA
                     LQFLQDHHLHLLIRIEYQEISSDENKYFELLDKFIRHSIQIFGRDTVAKWRFLYYEPHA
                     TIASPEELRRIYLRLQALVKSREERVQVGTYLPFSERTGTTTTQHDWQLSHGDVIDFIA
                     YEANPNEVVDFDKSADDDFTETQDYILSATSKLKAYLRKHRMEKSLFLMSWNTLTGNTR
                     YTNGTFFRGALVMRAVLDISREADAIGFWINTEQHEGERRARNISIDGLELFHFFNGKR
                     PAYYAVMFKERLRGRIVAQGKDYVMTEHADGYQLALLNCNNFNPRFSVEELFLRQRKKE
                     MHIRLLGMKPGAYQIRKFQFDRDHGALYSEWGKFNSKHGVDQEIMNYVINRSTPSLKVI
                     DEQMSADWSFYVYLDMNAIHFYEFRRMFDDMN"
     gene            17614..18825
                     /db_xref="GeneID:76998479"
                     /locus_tag="FLT43_RS21195"
                     /old_locus_tag="FLT43_21195"
     CDS             17614..18825
                     /codon_start=1
                     /db_xref="GeneID:76998479"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679326.1"
                     /locus_tag="FLT43_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21195"
                     /product="M20 family metallopeptidase"
                     /protein_id="WP_087443084.1"
                     /transl_table=11
                     /translation="MKTELFRRLDEKKERIIEIRRYLHAHPELSFQEENTAKYIAEFYT
                     DKPCVVREHVGGNGVVVTIDSGKPGKTLAIRADFDALPITEQTGLPFASQNPGVMHACG
                     HDGHTAYMLVLAETLMEMKDQLEGKVVILHQHAEETPPGGAIHMIQDGCLDGVDHVLGI
                     HVMSTMETGRIFYREGPIQTGRAYFKVKILGKGGHGSSPHMANDAIVAASEFVCAVQTI
                     VSRRLNPFDVGSITIGSFDGKGSFNVIKDAVELEGDVRAMTEETRSLIEQEIRRILSGL
                     QEMFGITYELDYNNDYPVLVNDPAFTEFVVKSLTQSGIPEVTSIERCEPQPPSEDFAYY
                     AQQRPSVFFYVGAMPDHGAYYPHHHPKFDINEDSLQIAAKAMGALVIDYMKEGGRDEDT
                     NSSV"
     gene            18800..20215
                     /db_xref="GeneID:76998480"
                     /locus_tag="FLT43_RS21200"
                     /old_locus_tag="FLT43_21200"
     CDS             18800..20215
                     /codon_start=1
                     /db_xref="GeneID:76998480"
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679327.1"
                     /locus_tag="FLT43_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21200"
                     /product="MFS transporter"
                     /protein_id="WP_087443085.1"
                     /transl_table=11
                     /translation="MKTPTVPYKGSDKLIVGIVFGVITFWLFAQSMVNIVPDVQADLGI
                     SLDTLNIAISLTALFSGIFIVVAGGMADRFGRMKLTYIGLILSIIGSLLLILAHGSGML
                     IAGRIIQGLSAACIMPATLALMKTYFEGPERQRALSFWSIGSWGGSGVCSFAGGAIATY
                     MGWRWIFVFSIVFAVLAMLLIKGTPESKVEQSGSKARFDFGGLVMFVITLVTLNLIITR
                     GSSFGWTSPITLSLAAVFLVSMVIFFKIEFRHANGFIDFSLFKNKAYTGATVSNFLLNA
                     AAGTLVVANTYVQIGRGFTAFESGLLSLGYLVCVLVMIRVGEKLLQKHGSRKPMITGSL
                     ITAIGIALMSFTFVPGFLYTLLVFVGFMLFGIGLGMYATPSTDTAVSNAPESKVGIASG
                     IYKMASSLGGSFGVAISASVYGVIAAAGSIELAAMVGLLTNVAFCVVSLLSVVITAPKG
                     SKQENAVLAPAAK"
     gene            20297..21484
                     /db_xref="GeneID:76998481"
                     /locus_tag="FLT43_RS21205"
                     /old_locus_tag="FLT43_21205"
     CDS             20297..21484
                     /GO_function="GO:0004180 - carboxypeptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998481"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006679328.1"
                     /locus_tag="FLT43_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_21205"
                     /product="amidohydrolase"
                     /protein_id="WP_087443086.1"
                     /transl_table=11
                     /translation="MRDQLLAMLDARKDEIIAIRRHLHAHPELSFQEEQTAKYIQDFYQ
                     GKEVKLDTEVGNGHGLIVTIQGGKPGKTIALRADFDALPIQEETGLPFASENPGVMHAC
                     GHDGHTAYLLVLADCLIQLKDELPGTIKIIHQHAEETPPGGAKSIVESGLLDDVEHIFG
                     VHVFPTGNVGEVMYRSGFAMAGRSYFKLGIQGKGGHGSSPHMANDAIVAAAHFVTTAQT
                     IISRRLNPFDTGVVTIGSFDGKGSFNVIKDYVELEGDVRYMTTETQALIDKEIHRIVKG
                     IEETFGVQATLTYTADYPPLYNHPEVTANVVRYLEQGVGDYLTAIHEGDMLSGSEDFAY
                     YLEKIPGCFFYIGCKPKNADEVYFNHHPKFDIDEDGLLVAAKSVAEVVCGYYGLK"
ORIGIN
        1 ttacgcatct gccaatcagc actacgcatg cgattacctc cgctattctg ggggtaggct
       61 ctgcaaagcg gttctcggcg gtgaagtggg gcatggctgg acgcatcgtg gtgacctggt
      121 tcattacgat tccgatctgt gcgggattat cgatgttgat cctcaaagtc attgattttc
      181 tgttttatta aaaaggggaa aagccggctc ggtggagtcg gctttttgat atgcctggga
      241 gctatgcttc ctgtctgtgt ggacgagtgc cgttcgcggt gcgggggcta ctttttacgc
      301 cgtggggcgc tgcctgtacg gctggccgtc gatttccggc ggttgccgct tcccgagcgc
      361 gggctgccgc tcgaatatct ccgtcgtctg cgcggtgcgt cgtcaccgcc atccgcagtg
      421 ctcagctttt ttccacctcc tttgccgggc aaaagggttc ccatgaacat tttggccacc
      481 ggcatgattt gttggacgct gctcataatc ttctgtactt tgcccatcgt atcgacgatg
      541 ccctcgatgc ctccgagctt gtcgatcatc gatttgagat cgcccatgga gaagttgccc
      601 agcagcttct tctccggctg agcggccacc tcaatcggcg tctcggcgac ggcattgaac
      661 gggacgatag gcgcttcctg gtaaggcgta tacccggaca actcaggata tccagcaggc
      721 aatccgggag gcgggccgtt gaagctccgg gtgttcatgc ggatgccggc ggggcgggcc
      781 cgggcctgat tccgggccgc ccgctccctg gccagcggag atgcggaatg catcgcatgg
      841 ggtccgcgca tgcgaggcac cgacatcagc tccaccggat ccggaatgcc aggccgccca
      901 ttgcggtgag gtactttcat ctcatcacga cctttttcat taaaatcatc atgcgtgtgc
      961 gtgttcaaaa agacggcggg aaattgccgt atgacttttg cacaatcgtc atattttgga
     1021 ttgtatttgt ggataggtta ctatacagta tgtggtaggc gaacaacacg tgtggacgat
     1081 cgcccgtggg tggacgccca atccttcgtg aaagcgctat tatgaatgcc tttattcatt
     1141 aaagcacgaa cacggtaacg cttgaaaagg cgctgtaaag gcagtacaat gaaattacat
     1201 gcgaagaagt aggagtggat aaggttgcaa ttgaagaaat tgaatgataa atcgatcgac
     1261 cagctgtttg aagcgatttt gacgctggag tcgctcgaag agtgctatat tttctttgat
     1321 gatctgtgca cggtgaatga aatccaatcc ttatcccagc ggctggaggt agcccgcatg
     1381 ttgggcaagg gctgcactta taatcagatt gaagcggaga cgggcgcgag tacggcgacg
     1441 atctcccgcg tgaagcgttg cttgaattac ggcaatgacg gttataaaat gacgctggaa
     1501 cgtctggggc gctaagcgat gcgcccgggc ctgttggtga ttagccacgg ttctcccgac
     1561 ggttcctggg ttacactggt agatgaagcg atggcgcagg cggcgtggcc ggaaggggtg
     1621 ccgatcgctt cttctttttt ggactgcgtg ccgggacgta cgattcagga cggcatcgat
     1681 gagctggagg cacaaggggt ggatgccatt ggcgtcatcc ctttgttcat atcgggcgga
     1741 agcacgcatg tcgatgagat agcttatgcg ctcggcgtca cttcggcgcc gctcgccgac
     1801 acgaagctgc cgccgttccg cctgcgggcg caggtgcgct acggccgccc gctggacggg
     1861 gcggccttgt tcgccgcggc ttgcggcggg gacgggccgg gcggtgatgg cccggcaggc
     1921 gagcccgagg cgggcacggt cctcctccac atggtggagg accgcttgcg cggcctcggc
     1981 gccggcgcgg gcgatgcggc gctgctcgtg gcgcacggca gccgccacga gcctttcgcg
     2041 ggccgctggc acgcgagcct gcgccgcctg gcgcggcagc tcgtgcagcg cagcgcctgc
     2101 gcggcggcgt cccacgcgct gctctgctgc gaggacatcg ccgcggcggc gcgcaagctg
     2161 cagcaggcgc tggcggtgat gcccgccgat gcgggcccgg cctgctggcg ggcgaccgca
     2221 cgctggcggc acgcgcggcg cttgccgagg ccgcggcccg gcgggactcg gccgccggga
     2281 gcggcgcgtg gcggtggtgc cggtgttcct gagcaccggc tattttacgg cgcgggttat
     2341 tcccgagcgg ctgggcgatg tgccggcgct ctatgacggg cgcccgctgc tgccgcatcc
     2401 ggccttggtg gagtggctct cccgcgaggg agagcggctg ctggccggga tgaaggccga
     2461 ggacggctga atgcggtggc cgggcgctgg cggctgggtt cggacaagct caggcagctc
     2521 gggcaggatc gggaatgatg ctcgacggcg catttcacag tgatatgttg gattttccat
     2581 agtataatca agtaagtaat caatctgtga aggtgcccgg catcagggag atgcggagca
     2641 ggcatggcgc cggaatggga atagaatgca aacgggtgac ttaaggaatg ataaaaaaag
     2701 caagattaat ctataacccg acttccgggc gggaggaagg gaagaagcgg ctggcggaca
     2761 ttctgcatat gctggatgcc gccgggatcg aggcgacggc gcatgcgacg gatggcgcgg
     2821 gcgatgcgac agccagcgcg gcggatgcga tcgaccgggg ctatgacatg atcatcgccg
     2881 ccggcgggga cggcacgctt aacgaggtta tcaacggcat ggccggcaag ccgtcacggc
     2941 cgccgcttgg cattattccg ctcggcacga cgaatgattt cgcccgtgcg ctgggcatcc
     3001 cccgccattg ggaggacgcc tgctcgatta ttacccggca gaagacgcgc gtcatcgatc
     3061 tggggcaggc gaatgacacg tatttcatca atatcgcggg cggcgggtcg ctgactgagc
     3121 tcacgtatga ggtgccgagc aagctgaaga cgatgatcgg acagctggct tattacatga
     3181 agggcctgga aaagatgacg agcctgcggc cgacggagct gcgcatcgag gtggacggcc
     3241 acggcgtgtt ccatgaggag ttcatgctgt tcctgattgc gaatacgaac tcggtcggcg
     3301 gcttcgagaa gctggcgccg ggggcgcgca tcgatgacgg cctgttcgat gtcatcatgc
     3361 tgaagaaatg caatctggcg gagttcatcc gcgtggcggg gatggcgctg cggggcgatc
     3421 atattctcga tccgctcatt atccacgtcc agtcgaagcg ggtgacggtg acgtcgccgg
     3481 atacggtgca gttgaatctg gacggcgaat acggcgggct gctgccggga acattccagg
     3541 tgctgccgtc gcatttgcgg atttttgccg acgttccgga ggcgcagcca gagcaaggat
     3601 aggcatggca tcccgctcgt ctgcggtggg cgcggcggtg gggggaagca gccaatgttg
     3661 agagtgccaa cgcagccttg cttatggcga tgctgctgcc tcggatccgg gtatggctat
     3721 ggcgccctgc cctggctcgg gcgaatggtg ttgcgccctc tgttgtgccc cggctcgggc
     3781 cgatggcgct gcggtcgtgt tatggactcg gctgcgtggt gtacggcgtt gcggcctgtt
     3841 agggcctcgg ccggggcgtg cgtatgcgtt gcggaagctg gagggcttgg cctgctgccg
     3901 gtgaggcggg gccaggtctt tttttgataa gatggatgtg ctggggaagg ttgcggtttt
     3961 ttgatacctg gtgcgattac ggttggctgc tgcacctgtc tgaaggaaag tagtccagtt
     4021 aattgcggga atcctgcaaa tatacagtaa ttttttgctt gtgcgtatct attttgtaga
     4081 attgctgcta ggatgcagta ttttgaacga aaagtccgaa tataggcggt tatgaggcga
     4141 aattgatgta tatttgcagg cttccttttt ccaaaaagag agcttggtgg aaatactgca
     4201 cttttgcagt ttttttgcag ctgttgaagg gaaagtaaag ggaaattgaa ggggaattga
     4261 ctgggattgg tgtatcgttt gcgcgagagc tctggttgtc ttttgaagca tggctcctga
     4321 agcggcggta cgcacgaact ttggggaaga agcgcatgtc tcggaaagta cctgaataca
     4381 tgatgtggcc atagaggatt ccggcatagg atgtgtattg tatatataga aggcaggctc
     4441 atagcaggct tatcatactt acatactctt aatcaagtta gcaagattcg gtcttggatg
     4501 tcgaacgggt ttggtggaag gcaactagag catcatattg acatgtagga acagcaagcg
     4561 atagagcgga ggatgttgtt gtgacaggga aaaagctagg caacggggcg gagcgccgga
     4621 aacgccgggg aacggcggca gcggtcaggg ctagagcggt cggggcgaaa tccgccgagg
     4681 cgaattcggc cgaggcgcga acggcggagg gctccacggc aaagaagcgc ggccaggcgg
     4741 gacagaagtc cgcttcggct ccggtaagca agaatgacga ggtcgtgctg gatattattg
     4801 ggctaaccca tgacggggaa ggcgtcggcc gggcggacgg cttcacgctg ttcgtcagcg
     4861 gcgcgctgcc gggggagcag gtgcgggcgc tcgtgctgaa ggtgaagaag cagtacggct
     4921 atgccaaagt attggagcgg ctcatcgaca gcgcgcatcg ggtggaactg gagcatccag
     4981 tgaatgcgta cggcggctgc cagctgcagc atctggaata tggcgagcag cttcgctgga
     5041 agcggcagca tgtcgtcgat gtgctggagc ggataggcaa gttccaggtg gagcatggag
     5101 ccgagactgg agacgcagac gggcagccgc cgattaaggt gctgccggtc attggaatgg
     5161 agcatccttg gcgctaccgt aacaagagcc agatgcctat cggggccgat ccgcggacgg
     5221 gcgagctgat tggggggtat ttcgccaagg cgagccaccg gattatcgat acggatgtaa
     5281 gcctgctcca gcatgagcgg aacgatgagg caatgcgcgc cgtgaagcgg attgcccgca
     5341 agtacggcat cgcgccgtac aacgaagaga cgcacacggg ccttcttcgt catgcgatta
     5401 tgcgtgtcgg cttccgtacg gacgagcaga tgattacgct cgtgacgaat ggggagaagt
     5461 tgccgcatga ggcggaaatt gtcgccgatc tggttgaagc gttgccgcag ttgacaagca
     5521 tctgccagaa catcaacacg aagcgcacga atgtcatcat gggagagaag acccgcgtat
     5581 tgtggggctc ggaatatatt acggattata tcggggacat cgcgttcaaa atatccgcac
     5641 gctcgttcta tcaggttaat ccggtgcaaa cggaagtgct gtatgacaag gcggtggagt
     5701 atgctggcct gacagggaac gagacggtca ttgacgcgta ctgcggcatc gggacgatct
     5761 cgctgttcct ggcgcagcgc gcgaagcgag tgcttggcgt cgagatcgtc gaggaagcga
     5821 tcgccgatgc acgccgcaat gccgaactga acggcgtgac gaatgcggag ttcgccgttg
     5881 gcgcggctga ggacgtaatc ccgcgctgga aggagcaggg cgtaacgcct gacgtcatcg
     5941 tcgtcgaccc gccgcgtaag ggctgcgata cggcgctgct cgacacgatg ctggccatgc
     6001 gccctgagcg cattgtgtac gtgtcctgca atccgtctac gttggcaagg gatgtgcggg
     6061 tgctggcgga tggcggttac cgtgttcttg aagtacagcc agtggatatg ttcccgcaga
     6121 cgacacatgt ggagtgttgc tcactgttgg tcaggaacga ctaatagttg aggtgtattg
     6181 gcggaaatag taaagagggg ctttcgccct ctcttttttt ctagccgatg gactatcgtt
     6241 ttccgtaaca acaagtgctt gatctgctaa tagtcgttct atataagagg agaaaatatc
     6301 cttctcacct tttcataatc agttggattt taaaactgga cttcgctcga gcgaaccatt
     6361 gtagcaaatt gggcaagaat gctattatga tggtttatga tttgttctgc cgttaatcca
     6421 tctgaatcgt aagtgctgtg gcaatcctct gccaattcta ctttgtagcc gcgcgaataa
     6481 ccactcttca ccgttgtgtc cacgcaatat tcggtttgta cgccgcatat cactagagta
     6541 tcaatacctt gatcccgtaa ccggggatgg agctcggaat ctagaaacga atccgcgtaa
     6601 tgtttaataa tgatatgatc atgtgcaagg ggaacgatct gttcatgcac ttgccatagc
     6661 ggttgattct ccgatcttag agaaccatgc ggctcagtaa acatgatata gaatacgggt
     6721 gaatttccct ttcgagcttt atcaattaat cgccttgtat tttctagcag gttctcttcc
     6781 tgataaagag attttccacc ataatctttc catacaaagg gcataacctg catgtcaata
     6841 attagtagcg cctttctcat ttcaggtgac cctccttgat cccaatttct ttttctcata
     6901 tttccataat ccatgtcggt tgcaatacgt atacaacgtt ccgccgtaca ttttggggaa
     6961 gcgtacttct gcgagttgtt ccgggtacaa tttgatgagc atcaccctgt catacgaaat
     7021 ataggctaca aaagatatgt aatggtctct gctcatctcg tgcttaatgg taacaaagta
     7081 atcctcttca atttcgtgaa cggttatttc gtgctcatcg ttctccgctt tggaaagcag
     7141 cggctccagt aacctgccgc aacatgaaat gcttgttgcc cccgtactgg tcataatatt
     7201 gccacagctt tgacacgcgt aaaattttac gttcttcata tttcctccgt cctgttcatt
     7261 cggatttaaa tctccggata aaatcttctc gatatttact cctaatatgt tggatagctc
     7321 cccaagcaag gatacatccg gacaccccaa tccgcgttcc cattttgaaa tcgtcttatc
     7381 actaatattc ataagaaggg ctaattcttt ttgagtcatt cttttctctt tacgaagact
     7441 ctgaattagc cttcccacct tgatgcaatc gatattgtcc gcctcctgta attttagagt
     7501 atcaagtata ttttcccctt tcaataaacg ctccgtagag tttactaacc tcccgattgc
     7561 tagatgatct tggaagggtt gtacgtacaa tgtctattcg gaaaaatttg gtccgaggca
     7621 gaccgttact caagtcatgt ggagtcggtg gctttgttgg tgaagaagga caattaaatc
     7681 gaagaagtat tgacggaact tagtaggaag aagcagggaa acctgcttct tttctgtata
     7741 tactcaagag ggatagatct atccgaaaat acttatatgc ataaatgatc gcgtataata
     7801 gctcgattgc aaaagaggag gaatcagaaa attgaaattc tatcgctatg tgttaagtat
     7861 cccacctttg gattgggagt gttgctttct tagcattgag gagtataagc agaactttgc
     7921 gaacaagtat aatcaaaata tagagtatta catgcaagtt attggggatt gtcaacagca
     7981 tctcgttgat gtcgacaacc ttgctgttgt aacatataaa gatctgtgtg caagcgttca
     8041 ttctgctgag ctgcgctgtc cagccatgat tttctctata ccgagtggcg atcagcgagg
     8101 ttcagctttg ttttgtatca tgtataagct tgaaaacgac ggggatacgt ttatttactc
     8161 tcctattcca cttgttcatc tagagcaaga tcaagcaggt gaaatagagc tttaattgtt
     8221 tgaattcaga ggtggcttga atgctaatca actgtgtgcc gataattgtt ttgaccatcg
     8281 tcgttttcgc ggagaaggaa taggagatac agggttacac aataatatgt gttcgaggac
     8341 acatctcaaa taaagaggcc tgcctttggg cgggcttttg acgtttttaa acagggccaa
     8401 tccccttttt ggtaggattt aactcgatta atgtcgaagt atggtgaaag atgaacagga
     8461 tggtaacact cgaaatgtaa atagagaagg gagattacaa tgaaagattt aaaaattctc
     8521 aaagaacgaa aagagtgcat ctttttcaaa cgagtgaaaa tgatagccgt aatggatgga
     8581 tcggagggaa tgcaccggct tccttttgat gataatgaga ggatctccat ttttgctcct
     8641 aaacattttg aagatcgtct ttctaaagat agatatccag attgttcgat attaacaatg
     8701 aaacacctaa aacagaagag agtaaatttg atgcctttac cgatcatgat ttagtaaaat
     8761 ggaaaatcat tccttaaaat acggagtgtt taataagcta taaagaaata gactgagagg
     8821 tataaatatg aaaaaattct taaaaatttt ctctattact attcttgtta ttgtaatcgt
     8881 gtctatagta gctttgctat tatttggacg taacaaccat agtaatttat ctggaagcgt
     8941 ttctgataaa atcgatcaat atttgacaaa tgaaaaattt cagggaaccg tcctaattgc
     9001 aaaggaaggt gaagttttat ttacaaaagg ttatggattg gcagccactg atttacctaa
     9061 tagcccaagc acgctctatc agattgcttc attatctaaa acattcactg cagtagcagt
     9121 catgcaacta gtagaaaagg aacttctaaa cttagataat ccaatttcgc aatactttcc
     9181 agactttccg aatggagagt ctattacaat aggtcatcta ctaagtcata gctcgggaat
     9241 tccggattat ctaaaggcga atttcgaatt tgactacagc aaagaatgga atccaaatga
     9301 tattgtaaaa accgttagcg attctgaatt agagtttacc ccaggtaaaa gctttagtta
     9361 tagtaatact ggttatgtga tgttaggact tattgttgaa aaagtcagcg gacagtcata
     9421 tgcaaattat atagaagagc atatttttga gccaagtaac atgtttaatt ctatgtttac
     9481 ggtttcggcc ggtataccaa aagcggaagg acatgtaggg gggaaagccg gacccttaat
     9541 gcataattct gcagcgtatg cagctgggga tatcatttct acagttgaag atttagaacg
     9601 gtttgacaga gccctgcgta ataatttatt gataagcaaa gaaacatcag aactgatgag
     9661 tatgacccat gctaaaaagt ttccgtatca atatggatat ggatggtata ctcaagatgt
     9721 catggggaaa aaagcagttg ggcattcagg aggatatcca agtggtttcc gtcattatgt
     9781 tacacggcta catgacgagg aattaacagt gatcgttctt agcaacgaga tgacggtgaa
     9841 ttcaaaaaga atcaaccgta atcttacatc catcgttctt caggagccaa tttggatatg
     9901 ggaagagaaa ctttaattat aaaagacttt tctcaagttt gataaaagat aatttagtaa
     9961 acttattgca aagaggggcc gatgcccctc tttcatctat ctacatttga ttctcttcca
    10021 tcgctcgaat cgactcggca accttcgcca tcatggaaca ttcaattcgt ttacggaaaa
    10081 catcacaact aaattcgtag gttccgttga tggagcccgt cgcatgcagg gcattggcag
    10141 gacagccccc gctgcagtag agcttagccc agcaatcctt gcactccggc ttcgtgtagc
    10201 agttgctctc tgtaaattgg cactgcagct ccggctgcgt gatgccatcc cagatgttcc
    10261 ccatgctgta cgcttcatcc cctacgaact ggtggcaagg gaacagctcg ccccatggcg
    10321 tgacagcgag gtattccgtg cctgatccgc agcccgtgat tcgcttctgg atgcaaggac
    10381 cttccgagag atctagcatg taatgataga atgtgaaccc tctgccttgt tcactgcgcg
    10441 caatcatttc tttggcgaga atttcgtact gattgtaaat ctccgggaga tccttctcgg
    10501 taagcgcata gggttcccgt ggatcacaga tgacaggttc catcgagatt ttgtcaaaac
    10561 caagatctgc gatatggaag atatcattgg tgaagtcgac attgttccgt gtatatgttc
    10621 cccgtacata gtattcctgg tctccacgct tttggatgaa ttcctggaac ttcggcacga
    10681 tagaatcata actgcctttg ccggtaacgg ttgtgcgcag ccgatcatga acctcttttc
    10741 ttccatccag gcttaagacg acattataca tttcctgatt taaaaactcg gtgatctcat
    10801 cgttcagcag catgccgttc gttgtgaagg tgaagcggaa ttttttcttc cattcctttt
    10861 ccttgcttcg tgcatacgct acaatctgtt tgacgacttt ccaagccata agcggttctc
    10921 cgccgaaaaa gtcaatgtca aggttgcggt gatggcccga atgctccagc aaataatcga
    10981 tagctctttg tccaacttct aagctcataa ttgctcgatc gccattgtac tttccttggc
    11041 tggcgaagca atattcgcat gacagattgc aggtatgcgc gacattgaga cagagcgcct
    11101 tcacatacgt ttttcgtttt tgtaaatcaa tagacagttc ctcatacgca tcctctgtaa
    11161 agagctgtcc attgcttatg agttcctcga cctctgagat cgtctctcgg atgctttcct
    11221 ctgaataatg tttttccttc attctcatta ggatttgttc gggtgctgca tgctcataca
    11281 gcgcaatgat ctcatacgcc aggtcatcaa caacatgcac tgagccacta taggtatcga
    11341 tcacgatgtt gtatccgttc agttgataat gatgaatcat actgccaatc aagctccttt
    11401 ttgactacaa attgcaggcg gctatccagt ataaacaact tcgccgtcct tgtaaggacg
    11461 gcggtgagtt tcaattccta tttgttcatt gcgttttcac aacgctggtt ggcaacgcca
    11521 caggaagtct tgcaagcaga ctggcaagat gtctggcaag cgccgcatcc gccgtgtttt
    11581 gcagtgtcca tcagtttgcg tgtactcagt gttacaattc ttttcatgat gaataactcc
    11641 tctaccattt cattagttat taacttgctg cgttgaacta tcgtagcagc aactttggct
    11701 gcacatcaat caaaaaggtc acacataaac ataccgtcag catttcattt cacatatgtg
    11761 gagtgctgtg cgttgatagt gagaaataaa gttgctgttc cctatgttca taacaaacct
    11821 ggcaaattac cgaatgggtt ttcagagaca agtccttgtt cacagatgga ttttattttt
    11881 ttattttttt tgtttacttt tccaaaaaaa tgatgataaa ataaagtcag ttgggaaaaa
    11941 gagtaattta tttaccgaaa atcccaatta attaatggcg ttaagaaggg ggggatccag
    12001 gaaatcaggg agaaagaacc gaaaaaagga ggttggtaaa tctaaaactt gaatgcgctt
    12061 tctcagcatc gtgacgaact ctatttcatc atgctgaaca ctggaaagca gcacaaatta
    12121 tttattccgt gaaggagggt taataatgaa gaagtttcta agctctgttt tagccgccat
    12181 tttgttaatg gcaactttag taacaggggt ggcgtttggc agccccgatc agggttactc
    12241 gggtgattat attgaaggtc aactcgtggt gtcggtcgag gaaccgttca tggattcgat
    12301 ccaaagcgtg gatgaattat tgatggaagc ggaatcgctc acggagagcg gttttacgat
    12361 tgccgattca ctgttcgggc aggatgccgg cagcttctcg gtgcaatcgc tggatagcga
    12421 tgtaagggct acggcgatag aaaaaatggg tttggtctat ttggtcgagt actctgtaga
    12481 ggactacaat tcaatcgatt ccgccaaaat aacgttggag gaaacattag acaacctcgg
    12541 cttcaatgtt cggtacgtca cggaaaaccg caaaatgtac gcgcttgaaa ctgcaaccgt
    12601 gcaggatgtt tcacctcaag atattcacaa taaccaacgt tggcattatg acatgattaa
    12661 ggttccgcaa gcctgggaga ttacgaccgg gtcaagctca gtgcggatcg gcgtgcttga
    12721 cacgggaatt gacagcaacc atccgaacct gaaaaatctg gtgaacacta gcttgggcag
    12781 cagctttgtg ggcggaacca caaacgatgg caatgggcac ggcactcatg tcgctggaac
    12841 gatcgccagt tatggatcgg tgtcaggcgt catgcagaac gcgaccctga ttcctattaa
    12901 agtgcttaac gacagcggtt caggttcgct gtatggcgtt caacaaggta ttgtttacgc
    12961 cgctaatgtt agagccgatg tcatcaatat gtcgctgggt ggcggcggtt acgatcaagg
    13021 gatggatgag gccattcaaa cggctgtcgg cttgggcacc atcgtggtgg ctgccgctgg
    13081 caatgacgga ctccccaaaa tttcttatcc ggcggcttac agcggttcga tcgcggttgg
    13141 ctccgtgacc tcgagcagaa cgcgttcaag cttctccaat tatggaccgg gtcttgatgt
    13201 gatggctcct gggtcgaaca tatacagcac atataagaac ggtcaatatg caaccctgtc
    13261 aggcacctcg atgtcaaccc ctcatgtaac gggcgtacta ggactgatga gatcggtcaa
    13321 tccgaatctt acctctgctg aagccgaaga gattctcaaa aatacagcgc agcctgccgg
    13381 aagttctgat cagtatgggc atggcattgt tgatgcgcac gctgctgtgt tagcggcaag
    13441 tcagcggtga cgatacgcaa gccccgagcg aacctggcat aatatccaca ggcataacca
    13501 acacaagcgt atcgctatac tggagtgctt ctactgacaa cgcgggcgta agtcgtccgc
    13561 aacaagcaaa tgccgtaacg gtaacgacgg attccggttc gtcacagccg tctccgacta
    13621 cgccttgagc tccaggtata tcgtataaga tcggggacga agcgacttac ggcggagcga
    13681 cataccagtg tcttcaagaa catatttcga tggcgggctg ggaaccgctt aacgtaccgg
    13741 cattatggtt agagaaataa ttgatccggg gtaaccgctc cccgaacaaa gcgccttcgc
    13801 agactgtctg caaggcgctt tttttgtggt tttaagtctg aacgacatct gatgtgatcg
    13861 gatacggcat gaccacgtgc ataatgaaca tattctgtca tgcaccctgc cgtttgatgc
    13921 tccggatgca atgctgaatt tataatttgt gataatgatg taagcggcgc tctaccctat
    13981 cttggataat ttgttttaag gaatcaggct tcacggatac cacataatca ccgtatttca
    14041 taaaataaga gctatcgatt tcaatgacct cgaagaggcg gagaggctgt ttgatatcct
    14101 tgaaaaccaa gccgaacctg acctgcaaac cttatatcat agagcaaaaa aattgaagaa
    14161 atatgaaaag gccatttttt ataaacagaa ggaagtcgag tcggctgcgg acgctcggga
    14221 taaggcatca accatcttag atataactgc tttgcatatt ttgaataatg gctatatcca
    14281 agcttttgaa tccgcacaat cgtgggaacg gcttctgacg cagtttgata gttggcaata
    14341 caccggactt ggcagaatga tgagtgaatg ctggtttgat tttataaaaa attagttcat
    14401 cgttggagta ggcgataatc cgggtcactc ctgttcctgt actcataccc taaatgaaga
    14461 caggggagga aaagaagtat gcccaatagc ggttcgcttt gtgcgaagtt ctcaaggatt
    14521 atcgggggcc agcccggctt tgccggcgga aaatgcgtct cgaccataaa tcgaaagcga
    14581 ataagagcaa cgattttggg gaaaagattt agcgtaacgt cttctttttc gttcgaatca
    14641 ttagatgaaa gaacgggcaa agcgctttgt gtaggcaggg cggccttctt agagaaagaa
    14701 gtcaatccat tcattacggc gattcgtaaa caaggaatca aagtgacgtc tgtccgtaac
    14761 gaatggctat tcgagcggcc cctcttgatg tatgtcaata ttgaagccgt ggaaaaaccg
    14821 cttgttttcg ccagaaaggt caggcgagcg ttagatgcga ttcatgaagg tttcaagctt
    14881 taatgcttga agcctttttg tctggaaatg gatgactgga gcgtctgcac ttgtctggac
    14941 aataaaaaaa ggctcacgta aactgaacta agcctaaggt ttttcaagaa atgctggcac
    15001 caaatgctgt catcgtccat caagcctaaa ccaagccaag gaggcgttca ccatgccgaa
    15061 tgcagcaacg aacaacaact atgagatcag catggaaaat attcgatcga tgccgccaac
    15121 gagttatttt ggaacgaaga ttctgttcgt gatcagcggg agcctgaccg tgaactgtac
    15181 ggctcgcgat tataagctgc aggctcatga tatcttgatc ctgaaccgca atgacaggca
    15241 tgagatcgca agccaggagg ataatatcgt cattgtgttg agcctgacgg cacagttctt
    15301 tgcccagcat gataaatcgt acttctccta tcacttcgac tgcttctcgc gggagatgga
    15361 ccccgggcgc gagcagatgg tcgcccttct gcggcgttat gttgccgaga ttatgattgc
    15421 ctactcgcga acaggcgcgc ttccgaacct ggagctgcag agcagcttat tccaaatgat
    15481 gctgctgctg actcgtttct tcaagactga ggctcctgtg cgtgaaggga gttctcacga
    15541 tgatgaacgg attatgcgca tcatccagga gattgagcag cgctacgacg agccgattac
    15601 cttaaatgag atcgcacaga aggagtattt atcggtttct tacctctctc gatatttcaa
    15661 gaaaatgacc gggtttggat tcgtgcagta cgtcaatctg gttcggctga agcatagtct
    15721 ggatgatctg ctgcattcca cagattcgtt atctcatatt gcgttgaagc atggatttgc
    15781 cagctcgaaa cacttcaatg ccgtctttaa agcggcatac gggatgtccc ccgctcaata
    15841 ccggaaggag cattcggagc accaggatga tgtacagcca gcggctaacc atgcttccga
    15901 gcccagaacg gtgctgcaat ccccggatat tctggcgaag cttgcccagt acattgagac
    15961 aggggagcag atctcggata ttagcgaggc tgtattcgag aaccggcaga tcgagcttga
    16021 cccaacccgg caggaagaag tagcggcttc cacgcatgtt cttttcatcg gccagctgaa
    16081 ggaactcctt aatgagaatg tcaaagagca ggttctcatg gctcagcagg agctgcgcat
    16141 ccgttatatc ggaattcgca acctgatctt tggcaagacg ctgcttcccg aagtggaaac
    16201 ggacgagctg gtggctacct ctacgccgtt catgaattcc gatctggccc tccagttcct
    16261 gcaagatcat catctccacc tcctgatccg catcgaatac caggagattt cctcggacga
    16321 gaacaagtat ttcgagctgc tggacaagtt tatccgtcac tcgattcaga tttttggacg
    16381 cgataccgta gcgaagtggc gcttcctgta ttatgagcct catgccacga ttgcctcccc
    16441 cgaagagctg cggcgaatat atcttcgcct tcaggcttta gtgaagagca gggaagagcg
    16501 agtgcaagtg gggacctatc ttcctttttc cgaacgaaca gggacaacga cgacacagca
    16561 tgactggcaa ttaagccacg gcgacgtgat tgacttcatt gcatacgaag cgaatccgaa
    16621 cgaagtcgtt gatttcgata aatcggctga cgatgatttc accgagaccc aggactatat
    16681 cctctccgcg acctccaagc tgaaagctta tttaaggaag catcgcatgg aaaaatcgct
    16741 gtttctcatg tcttggaata cgttgacggg gaatacgagg tatacgaacg gaacgttttt
    16801 ccgcggtgcc ttagtgatga gggcggtgct ggatataagc cgcgaggccg atgcgatcgg
    16861 cttctggatc aatacggagc agcatgaggg ggagcgccgc gcgcggaata taagcattga
    16921 cgggctggag ctgtttcact ttttcaatgg gaagagacct gcttattacg ctgtcatgtt
    16981 caaggaacga ttaagaggac gaattgtggc gcaagggaaa gattatgtga tgacggaaca
    17041 cgccgatgga taccagctcg cgctattgaa ctgcaataac ttcaatcctc gcttctcggt
    17101 ggaagagctg ttcctaagac agcggaagaa ggagatgcat attcgcctgc tcggcatgaa
    17161 gccaggtgcg tatcagattc gcaaattcca attcgaccgc gatcacgggg cattgtattc
    17221 ggagtggggg aagttcaaca gcaagcatgg cgtcgatcag gagattatga attatgtcat
    17281 caacagatca accccttcct tgaaagtcat agacgagcag atgagcgctg attggtcctt
    17341 ttatgtgtac ttggacatga acgcgattca cttttatgag ttccgtagaa tgttcgatga
    17401 tatgaactaa atcacatttg acgaaagtgg gtgaaaatct cccctcctgt tttgtccaag
    17461 cttgaagctc taacaagaag acggcaaaaa cgaaggacat gggagtgcaa aaacagggcc
    17521 gaatgtaacc gcttaccctc ctataataaa ggcatgaaaa catgtttctt cactggccgg
    17581 tgataagcat catgttatag gagggcagag gtcatgaaga cggaactatt tagacgactg
    17641 gacgagaaaa aagaacgcat catcgagatt agacgctatc tgcatgcgca tccggagctt
    17701 tccttccagg aggagaacac cgcgaagtat atcgctgaat tctatacaga taagccctgt
    17761 gtcgttcgcg agcatgtcgg cggcaacggg gttgttgtca cgattgatag cggcaagccg
    17821 ggcaagacct tggcgatccg cgcggatttc gacgcgcttc cgatcacgga gcagacggga
    17881 cttccctttg cctcgcagaa tccgggcgtc atgcacgctt gcggacatga tggacatacg
    17941 gcttatatgc ttgtccttgc cgagacgtta atggagatga aggatcagtt agagggcaag
    18001 gtcgttattt tgcatcaaca tgcggaagaa acaccgcctg gcggagcgat tcatatgatc
    18061 caggacggct gcctggatgg ggtagaccat gtgctcggca tccacgtcat gtctactatg
    18121 gagacgggaa gaatctttta ccgtgaagga ccgatccaga cgggacgcgc ctacttcaag
    18181 gtgaagattc ttggcaaagg cggccatgga tcctccccgc atatggctaa tgacgccatt
    18241 gttgccgcaa gcgaattcgt atgcgccgtg caaacgatcg taagccgccg cttgaatccg
    18301 tttgatgtcg gctccattac gattggctct tttgacggta aaggaagctt caatgtcatt
    18361 aaagacgcgg tcgagctgga aggcgatgtt cgagcgatga cggaagagac ccgcagcttg
    18421 attgaacagg aaattcgccg catcttatcc ggacttcaag aaatgttcgg gatcacgtat
    18481 gagcttgact ataacaatga ctatcctgtt ctcgtcaatg atccggcatt cacggaattc
    18541 gtggtgaagt cgctgactca gagcggcatt cccgaggtca cctcgatcga gcgctgcgaa
    18601 ccgcagccgc cttccgagga cttcgcttat tacgcgcaac agcgtccaag cgtattcttc
    18661 tatgtaggcg cgatgcctga ccatggagcg tattaccctc atcatcaccc taaattcgat
    18721 atcaatgaag actccttgca gattgctgcg aaagctatgg gtgcactcgt tatagactac
    18781 atgaaagagg gcggaagaga tgaagacacc aacagttccg tataaaggca gcgataaact
    18841 tatcgtaggg atcgtgttcg gggtcatcac cttctggctc ttcgcgcaat ccatggtcaa
    18901 tattgttcct gacgttcagg ctgatctcgg aatatctctc gatacgctga acatcgccat
    18961 cagcttgacg gcattattct cggggatttt tatcgtcgtt gccggcggca tggcggacag
    19021 gttcggacga atgaagctga cgtacattgg gcttattctt agtattattg gttccttatt
    19081 gctcattctt gcgcatggtt ccgggatgct gatcgcaggc cggattatcc aaggtctgtc
    19141 tgcagcctgc atcatgccgg caacgctggc tctgatgaag acgtacttcg agggaccaga
    19201 gagacagcgg gcgttaagct tctggtccat cggatcttgg ggcggttccg gggtatgctc
    19261 cttcgccggc ggcgccatcg ccacgtacat gggctggcgc tggatcttcg tcttctccat
    19321 cgtgttcgct gtgctcgcga tgctgcttat caagggtacg ccggagagca aggtcgaaca
    19381 atcgggcagc aaggcacgct tcgacttcgg cggcttggtt atgttcgtga ttacgctcgt
    19441 taccttgaac ctgatcatta cccgaggctc ctccttcggc tggacaagcc cgattacctt
    19501 gtctttggct gccgtgttcc ttgtgtcgat ggtcattttc ttcaaaattg agttccgtca
    19561 tgcgaatgga ttcattgact tttctctgtt caaaaataaa gcttataccg gggcaaccgt
    19621 gtcgaacttc ttattgaatg ccgcagcagg caccttggtg gtcgcgaata cgtacgttca
    19681 gattgggcgc ggctttaccg ctttcgaatc cgggctcttg tccctcggct acttggtgtg
    19741 tgttctcgtc atgattcgtg tcggcgagaa gctgctgcag aagcacggct cgcgcaagcc
    19801 aatgattacg ggctcactca ttacggcgat tggaattgcc ttgatgtcat tcacctttgt
    19861 cccaggcttt ctctatacgc tgcttgtgtt tgtcggcttc atgctcttcg gcatcggact
    19921 tggcatgtac gcgacgccat cgacggatac ggcggtctcc aatgcgccgg agagcaaggt
    19981 cggtattgcg tccgggatct ataaaatggc gagctcgctt ggcggttcgt tcggtgtcgc
    20041 catctccgca agtgtgtatg gggttatcgc tgccgccgga agtatcgaac tggccgccat
    20101 ggtcggactg ttaacgaatg ttgcattctg tgtcgtatcc ttactgtcag tcgttatcac
    20161 ggcaccaaag ggcagcaaac aagagaatgc agttctcgct ccggctgcaa aataagaatg
    20221 ccgattagag cgcttggaag cttggaggtt tgggattaga ttagagttat atagagattc
    20281 acaggaggat atgaacatgc gtgaccaatt attagcgatg ctcgatgcac gtaaggatga
    20341 gatcattgcg attcgcaggc atctgcatgc ccatccggag ctatctttcc aagaggaaca
    20401 gaccgcgaag tatattcaag acttctatca aggcaaagag gtgaagctgg atacggaagt
    20461 cggaaacggg cacggcctta tcgtcacgat tcagggcggc aagccgggca agacgatcgc
    20521 gctgcgggcg gatttcgatg cgcttccgat tcaggaagag acgggtcttc cctttgcttc
    20581 tgaaaatccc ggcgttatgc acgcttgcgg ccatgacggg cataccgctt acttgctcgt
    20641 gctggcggac tgcttgattc agctcaagga tgagcttcct ggcacgatca agatcattca
    20701 tcagcatgcg gaggaaacgc ctcccggggg ggccaagagc atcgtggagt ccggccttct
    20761 ggatgacgtg gagcatatct tcggcgttca cgtcttccct acggggaatg tcggcgaagt
    20821 gatgtaccgg agcggctttg cgatggcagg ccgaagctac ttcaagctcg gcattcaggg
    20881 caaaggcggc cacggctcct cgccgcatat ggccaatgac gcgatcgtcg ccgccgcgca
    20941 cttcgtcacg acggcgcaga cgattattag ccgccgcctg aatccattcg ataccggcgt
    21001 cgtgacgatc ggctccttcg acggcaaagg cagctttaac gtcatcaagg actatgtcga
    21061 gcttgaaggc gacgtgcgtt acatgacgac agagacccaa gcgttgatcg ataaagaaat
    21121 tcatcgcatc gtcaaaggga ttgaagagac gttcggcgtc caagcgaccc taacctatac
    21181 ggccgattat ccgccgctct acaatcatcc ggaagtgacc gcgaacgtcg ttcggtatct
    21241 ggagcaggga gtaggcgatt atttgacagc tatccatgaa ggcgatatgc tatccgggtc
    21301 tgaggacttt gcgtactatt tggaaaaaat cccgggctgc ttcttctaca ttggctgcaa
    21361 gccgaagaac gccgatgaag tctacttcaa tcaccatccg aagttcgata tcgacgagga
    21421 cggactgctc gtggccgcga agtcggttgc cgaagtggtg tgcgggtatt atgggttgaa
    21481 gtgatgggcg cagttgatgg atggaaggtt ataggaagca tttgagagtg gattagggta
    21541 ctgaacgttg aaagtaagct gagttttgta aaaatcgaat cgtgttgaag gtatcccctt
    21601 gtggttaaca tcttgagatt gttggta
//
