LOCUS       NZ_CP041405            23891 bp    DNA     circular CON 07-APR-2024
DEFINITION  Paenibacillus thiaminolyticus strain NRRL B-4156 chromosome.
ACCESSION   NZ_CP041405
VERSION     NZ_CP041405.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus thiaminolyticus
  ORGANISM  Paenibacillus thiaminolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Paenibacillus thiaminolyticus NRRL B-4156
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2019) Institute of Personalized Medicine, Penn
            State College of Medicine, 500 University Dr, Hershey, PA 17033, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2018
            Assembly Method :: Canu v. 08/2018; Pilon v. 08/2018
            Assembly Name                     :: PSU_Pthia_1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007066085.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 14:58:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,886
            CDSs (total)                      :: 5,776
            Genes (coding)                    :: 5,673
            CDSs (with protein)               :: 5,673
            Genes (RNA)                       :: 110
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 52 of 103
            Pseudo Genes (incomplete)         :: 68 of 103
            Pseudo Genes (internal stop)      :: 17 of 103
            Pseudo Genes (multiple problems)  :: 28 of 103
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:43:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4223299
            Orig. end                         :: 4247190
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041405.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Schiff/Broach Lab 500
            University Drive Hershey, PA 17033
            Chromosome not circularized.
FEATURES             Location/Qualifiers
     region          1..23891
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="11"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23891
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23891
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13891](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13891)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            29..1213
                     /db_xref="GeneID:76998026"
                     /locus_tag="FLT43_RS18870"
                     /old_locus_tag="FLT43_18870"
     CDS             29..1213
                     /codon_start=1
                     /db_xref="GeneID:76998026"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678408.1"
                     /locus_tag="FLT43_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18870"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_087444116.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.8e-63, bitscore:
                     212.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKSLILDTDMLTNEMKLILEIITSDRPEDLRKDKAGLFKDCKWD
                     AFLRLAMHHRVYSVLYMQMKDMGDDMVPPAVIQRLYRQYCANTLRMLHLSSEIEHIGKE
                     LTGRGLRCLFLKGPVLGQDLYGSVSLRTCSDLDLLVPLAELVRAETILITLGYEKDDYI
                     ESVLGDWKWRHHHLTFFHPVKGIKVELHWRLNPFPSKEPKFNELWLRKRRSTLFGSPIY
                     YLGREDLFVFLVTHGARHGWSRLRWLLDIKQLLNQQPDHGQIMNRLRRRRCVRAGGQSV
                     VLASSLLQAPLAPELQQLASRRRSVRLAQGAMFYLSQMVHLHKEPIPEEVGAYHKRHLF
                     ALMPLRHKCLFILSFMMPYPEDVKVIRLPRMLHYIYIPLRPFLWAWRKSVGVQK"
     gene            1210..2412
                     /db_xref="GeneID:76998027"
                     /locus_tag="FLT43_RS18875"
                     /old_locus_tag="FLT43_18875"
     CDS             1210..2412
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998027"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678407.1"
                     /locus_tag="FLT43_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18875"
                     /product="glycosyltransferase"
                     /protein_id="WP_087444115.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.5e-24,
                     bitscore: 85.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVLFASFDMEVGGVERSLAGLLEHFDYERYQAELMLYRHQGDF
                     MPLLPEQVRLLEEQRAYATFRKSIGDIIKSRQLLIGLGRLTAKVHADMAGKARGCAETG
                     YHQMQLMWRYTLPFLPRNKQLYDAAVSFLWPHYYVAEKVDARTKIAWIHTDYSTVATNV
                     HSDLKLWSKFDHIIAVSPSCREAFLAKYGTLRDKVTVIENIISPDYIKMMSEVSVDSPM
                     AADPRFKLVTVARLSHAKGIDQAVMALKKLREKGLEDIAWYVVGYGGDEEMIRGLIAKN
                     RLQEDFILLGKQYNPYPFIKQADLYVQPSRYEGKAVTVTEAQILSKPVLITRYPTAQSQ
                     VADGKDGYITDLSVEGLAEGIEHLYRDRQLRGRLADMCSRTQYGNAGELNKLYALLDDN
                     G"
     gene            2424..3395
                     /db_xref="GeneID:76998028"
                     /locus_tag="FLT43_RS18880"
                     /old_locus_tag="FLT43_18880"
     CDS             2424..3395
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678406.1"
                     /locus_tag="FLT43_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18880"
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="WP_087444114.1"
                     /transl_table=11
                     /translation="MDNILLLDTSVGSLNKGDEIIMKCVRRQLSGITSQANVFTVPTHL
                     SPFGWFQVMRDSLRVQFYTRAKYKFVGGTNLLTMDMFTHFPQWNINVFNYRPLQGSILL
                     GVGAGKGEKIKRYTKMLYRKVLSHEYVHSVRDERTWRFVTDLGLKALNTGCPTMWALTP
                     EHCQDIPKGKSDAVVFTLTDYARAPRQDQLLIDLLIRSYRKVYFWVQGADDYAYFHTLS
                     NTASIHVIPPSLEEYEAVLSTDVDFVGTRLHAGIYAMRHKKRSIIIAVDERARGMSETY
                     ALNTVDRTDLAGLEAMIHSEFATNVRMNLEAIQAWLDQFKQR"
     gene            3420..4685
                     /db_xref="GeneID:76998029"
                     /locus_tag="FLT43_RS18885"
                     /old_locus_tag="FLT43_18885"
     CDS             3420..4685
                     /codon_start=1
                     /db_xref="GeneID:76998029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678405.1"
                     /locus_tag="FLT43_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18885"
                     /product="peptidase"
                     /protein_id="WP_087444113.1"
                     /transl_table=11
                     /translation="MIQLTREQIKVNHNRVDYFFQVDPRLQKYFRASNHLFMKYNYDIS
                     GLPASILSIPFAANMMPLAWLTDATLYVDELDRSFYDCLAELKQAYQEMFPHFPLKGQI
                     KVGQVSSYHYQPEHEAAVLFSGGLDALTTYIRHRDKKPLLITEYGWHEGDCTDSEVWTA
                     DREHAEAFARKEGLSNILVESNYGTFVYPQRIDRDFRRPLGDTWWHGLHHGLAIISAAV
                     PAACLLQVKTVYIASSHTIGNTYSCASDPSTDNLIRYGAGDVFHDGYELSRQDKVKVVV
                     DHYAAANDKTAVRVCYRNTENCCQCEKCVRTIMGIAAEGHDPNDYGFPVPDELSGFLKR
                     FLKREVKFFTNIQIERLWKPIQERMRENPDNVKDQDLLSWFPEYDFVAQRRKERFRYRV
                     TQFFPIIRRKVRTGLQQIRETR"
     gene            4672..6264
                     /db_xref="GeneID:76998030"
                     /locus_tag="FLT43_RS18890"
                     /old_locus_tag="FLT43_18890"
     CDS             4672..6264
                     /codon_start=1
                     /db_xref="GeneID:76998030"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222557.1"
                     /locus_tag="FLT43_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18890"
                     /product="sugar translocase"
                     /protein_id="WP_244194320.1"
                     /sec_met_domain="Polysacc_synt (E-value: 3.7e-11, bitscore:
                     41.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKPGKRAGTGMRIRNSLYNIFFGLLGQAISTIMGFVVRTVFIWTL
                     GVEYLGVSGLFSDVLMLLSLANLGFETAIIYSLYQPLADRDEARIKAFMHLFRKAYLFI
                     GMLVLVLGLSLIPFLDVFIQGETTVSHIEVIYVLFLLNSVSTYFFAYKQAIIVADQQQH
                     VISRIHSVYVIAMNTIQIIVLLCSKNYILFLVIQIGMSVLRNKYISRVADRKYEFLREP
                     VSTPLDKGEKKTFFQNLRSLLMYKVSGVVINGTDNLIIANLFGVIWVGLYSNYYLILTT
                     LTTFVSYFFYSLTASVGNLNATEDKEKKFFFYRVLRLANFWVFGLSAVCLWNLLDPVII
                     LWLGGSFVLGKETLLAILLNFYTTGMQNASTMFRDTTGMFRRGRYSPLIAAAMNIGLSI
                     TLARFIGMPGVFLGTVISRLLTYFWVDPYLLHKHVFLQPLRPYFTRYALHAVLVLLAAS
                     LCGWLAGLLTLPLLWDIAVRVLLCLSVTNLIFYVCFRKSSEFIYLTNIAKANMGKLPIL
                     TKFNPVIRREETR"
     gene            6264..7292
                     /db_xref="GeneID:76998031"
                     /gene="galE"
                     /locus_tag="FLT43_RS18895"
                     /old_locus_tag="FLT43_18895"
     CDS             6264..7292
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-199). E-value: 1.9e-08.
                     Score: 25.7. Matches aSDomain:
                     nrpspksdomains_FLT43_RS18895_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GeneID:76998031"
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678403.1"
                     /locus_tag="FLT43_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18895"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_087444112.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5e-13, bitscore:
                     47.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.4e-14,
                     bitscore: 52.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAILITGGAGYIGSHTCVEMLEAGYDIVVLDNFSNSHPEAIRRIS
                     DITGKGFAFYEADLLDEQRLNRIFEGHRIDAVIHFAGLKAVGESVQVPLEYYHTNLTST
                     LVLCRAMAKHGVYSLVFSSSASVYGVPECVPISEEASLGAVSPYGRTKQMIEQVLQDLA
                     SSDPRWGISILRYFNPVGAHKSGKIGESPNGTPNNLMPFITQVAVGRLPSLKVYGSDYP
                     TKDGTGIRDYIHVVDLAQGHLKALEHLDHINGVEFYNLGTGRGFTVLEMIHSFEKVSGI
                     QIPYEIVGRRPGDIGICYADPTKSHISLGWFPKYGITDMCEDSWNWQVHNPQGYCERIT
                     AG"
     CDS_motif       6270..6335
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLT43_RS18895_0001"
                     /evalue="8.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="FLT43_RS18895"
                     /protein_end="24"
                     /protein_start="2"
                     /score="15.2"
                     /tool="antismash"
                     /translation="ILITGGAGYIGSHTCVEMLEAG"
     aSDomain        6276..6860
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLT43_RS18895_NAD_binding_4.1"
                     /evalue="1.90E-08"
                     /label="FLT43_RS18895_NAD_binding_4.1"
                     /locus_tag="FLT43_RS18895"
                     /protein_end="199"
                     /protein_start="4"
                     /score="25.7"
                     /tool="antismash"
                     /translation="ITGGAGYIGSHTCVEMLEAGYDIVVLDNFSNSHPEAIRRISDITG
                     KGFAFYEADLLDEQRLNRIFEGHRIDAVIHFAGLKAVGESVQVPLEYYHTNLTSTLVLC
                     RAMAKHGVYSLVFSSSASVYGVPECVPISEEASLGAVSPYGRTKQMIEQVLQDLASSDP
                     RWGISILRYFNPVGAHKSGKIGESPNGTPNNL"
     CDS_motif       6576..6632
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FLT43_RS18895_0002"
                     /evalue="6.10E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="FLT43_RS18895"
                     /protein_end="123"
                     /protein_start="104"
                     /score="6.1"
                     /tool="antismash"
                     /translation="LVLCRAMAKHGVYSLVFSS"
     regulatory      7382..7467
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            7485..7655
                     /db_xref="GeneID:76998032"
                     /locus_tag="FLT43_RS18900"
                     /old_locus_tag="FLT43_18900"
     CDS             7485..7655
                     /codon_start=1
                     /db_xref="GeneID:76998032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639518.1"
                     /locus_tag="FLT43_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18900"
                     /product="anti-repressor SinI family protein"
                     /protein_id="WP_115057747.1"
                     /transl_table=11
                     /translation="MVEAVTGNNEQLDKDWVAIILTARQMGLSIADIRKLLRDFQAQSD
                     PEWPLHVNSEA"
     gene            complement(7778..8113)
                     /db_xref="GeneID:76998033"
                     /gene="sinI"
                     /locus_tag="FLT43_RS18905"
                     /old_locus_tag="FLT43_18905"
     CDS             complement(7778..8113)
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998033"
                     /gene="sinI"
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678401.1"
                     /locus_tag="FLT43_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18905"
                     /product="DNA-binding anti-repressor SinI"
                     /protein_id="WP_087444111.1"
                     /transl_table=11
                     /translation="MIGERIQILRRKKNYSLSELSERAGVAKSYLSSIERGIQQNPSIQ
                     FLEKISVILGVSVEELLQDKEASNEAEVLDEEWTNLVKEAMASGVSKEQFKEFLEYNKW
                     KLTREES"
     gene            complement(8181..10004)
                     /db_xref="GeneID:76998034"
                     /locus_tag="FLT43_RS18910"
                     /old_locus_tag="FLT43_18910"
     CDS             complement(8181..10004)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998034"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678400.1"
                     /locus_tag="FLT43_RS18910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18910"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_087444110.1"
                     /transl_table=11
                     /translation="MNSIILYMKRLHQTAGLQLSINIIGMVISSLLEGMTFLLLIPMLT
                     VGGVLLSEPAWENRLRFLNILHSLPQASSLAIILTVYLLIVVTQNLIHRAVTVRNAEIE
                     QHFSRQLRYENYSALLRAQWPFFINRRTSDLVNALTIETARVLGGISLLLQFITSALFT
                     LLQIIFAFWISPKITLFVIACGAMLAFLSRGFIRKSKQLGSQTSKLAQAYLAGITDQLQ
                     GMKDIKSNNLEPSRLEWHQQLTEGTMQEQLDYVRLRLNSQLLYKIASSLLIAGFIFTSF
                     RFFPSEGPSLLIVILLFARLWPRFTSLQSKLEQLASTIPAFKALQQLQRDCKLAADQAI
                     TLTESPAPGPGHWFVMQGIEVRNLSFRYQPQLPVYALQNISVHIPAQGMTAIVGKSGAG
                     KSTFIDILMGLMQPESGQILVDGIAITNDNLLAYRRSIGYVAQDPFLYNATIRENLLMV
                     KPSATENELWEALDFSSAAEFVRKLPHQLETLIGDRGIRLSGGERQRLVLARAIIRQPS
                     ILVLDEATSALDTENEKKILTALHRLKDRITVIVVAHRLSTIQNAEQILVIHDGKLAEQ
                     GTFLSLSSEKKSIFANLLQNQEAQPVNVYTL"
     gene            complement(10001..10462)
                     /db_xref="GeneID:76998035"
                     /locus_tag="FLT43_RS18915"
                     /old_locus_tag="FLT43_18915"
     CDS             complement(10001..10462)
                     /codon_start=1
                     /db_xref="GeneID:76998035"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160861.1"
                     /locus_tag="FLT43_RS18915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18915"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_087444109.1"
                     /sec_met_domain="PF13471 (E-value: 4.9e-24, bitscore: 83.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLRRWIWLCLSDRKTFLLFAEAFLYLGWARILLYFPFAKISPL
                     LGRRSMETPEVHDPSHTKTMKHIRSAIQIVSRHTFWESKCLVRAMAGMKMLEKRNLHST
                     LYLGTGKNKNGELIAHAWLRSGSIYITGAEMMKQFVVVEKFAKSAGTDP"
     gene            complement(10459..10758)
                     /db_xref="GeneID:76998036"
                     /locus_tag="FLT43_RS18920"
                     /old_locus_tag="FLT43_18920"
     CDS             complement(10459..10758)
                     /codon_start=1
                     /db_xref="GeneID:76998036"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678398.1"
                     /locus_tag="FLT43_RS18920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18920"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_087444108.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.3e-22,
                     bitscore: 77.2, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-12, bitscore: 46.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLHSITPVDTLVQCEGHIVSDMAGEKVMLSVQKGKYYNLGTLG
                     GEIWDMLITPVKAEHIIRSILSAYEVESSECEEDILLFLSDLEHEGLIRHVKRL"
     aSDomain        complement(10477..10710)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FLT43_RS18920_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.10E-24"
                     /identifier="RREFam002.1"
                     /label="FLT43_RS18920"
                     /locus_tag="FLT43_RS18920"
                     /protein_end="94"
                     /protein_start="16"
                     /score="77.2"
                     /tool="antismash"
                     /translation="EGHIVSDMAGEKVMLSVQKGKYYNLGTLGGEIWDMLITPVKAEHI
                     IRSILSAYEVESSECEEDILLFLSDLEHEGLIR"
     gene            complement(10755..11789)
                     /db_xref="GeneID:76998037"
                     /locus_tag="FLT43_RS18925"
                     /old_locus_tag="FLT43_18925"
     CDS             complement(10755..11789)
                     /codon_start=1
                     /db_xref="GeneID:76998037"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FLT43_RS18925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FLT43_18925"
                     /product="aldolase"
                     /protein_id="WP_181823464.1"
                     /transl_table=11
                     /translation="MNAVTGAVPLYFSTGIRVPLFSNLQTLGEMSMTERAAVRTDHYKA
                     FGFRIESDFVLPELPLAGEREPLDNITVRRTDLQPLWNSSIHFYGNFAILDHGRTVMFR
                     VPGAAIYAVQDASSILVSPFDQAEENWVRLFILGTCMGILLLQRKIMPLHGSAVAIDGK
                     AYAIIGESGAGKSTLALHLMSEGYPLLSDDVIPVVMTRGSPWVVPSYPQQKLWVDTLKH
                     MGMDNANYTPLYERNTKFAVPAGSNFHEKPLPLASIFELVPWDAATHIAPIQGMERFRV
                     LFHHTYRNLLVQPLGLMEWHFKTLSSFIRQVGMYRLHRPMVGFSTLDLTSHILNIIRQG
                     ENDQ"
     gene            complement(11802..11939)
                     /db_xref="GeneID:76998038"
                     /locus_tag="FLT43_RS18930"
                     /old_locus_tag="FLT43_18930"
     CDS             complement(11802..11939)
                     /codon_start=1
                     /db_xref="GeneID:76998038"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172970.1"
                     /locus_tag="FLT43_RS18930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18930"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_115057746.1"
                     /transl_table=11
                     /translation="MKKQYSKPSLEVLDVHQTMAGPGLSTPDAFQPDPDEDVHYDPMDS
                     "
     CDS_motif       complement(11880..11939)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKQYSKPSLEVLDVHQTMA"
                     /locus_tag="FLT43_RS18930_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(11802..11879)
                     /prepeptide="core"
                     /locus_tag="FLT43_RS18930_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-9.90"
                     /molecular_weight="2684.7"
                     /monoisotopic_mass="2683.1"
                     /core_sequence="GPGLSTPDAFQPDPDEDVHYDPMDS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKQYSKPSLEVLDVHQTMA"
                     /leader_location="[11879:11939](-)"
     gene            complement(11954..13891)
                     /db_xref="GeneID:76998039"
                     /locus_tag="FLT43_RS18935"
                     /old_locus_tag="FLT43_18935"
     CDS             complement(11954..13891)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998039"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019913511.1"
                     /locus_tag="FLT43_RS18935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18935"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_087444106.1"
                     /sec_met_domain="GATase_7 (E-value: 2.8e-18, bitscore:
                     64.4, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 2.7e-25, bitscore:
                     88.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAVAGIYHLQHDKLEPGLGRQMIDALRRFPADYVSSWSNGSLFL
                     GSLQQCITPQSINEVLPCYDPVTSLAITSDAIIDNRDELADQLQLSKQARQTITDSQLI
                     LQAYMKWGHDMPKHLVGDFAFIIWDGRDRTMFGARDFSGTRTLYFHQSPELFSFCTIME
                     PLLTLPHVKRDLNEHWISQFLAIPITTDAVDSFSTVYQSIKQIPPSHSIFVANGKVIFQ
                     QYCRLQHTEKLVLTSNEEYEEALRDVFQTAVQARLRTFRQVGAHLSGGLDSGSVVSFAA
                     PMLKANNKSLYTFSYYPIEGFSDFTSCSRFADEREYIRSTAEHVGNIEMNVSSYPSSNP
                     YSVIDEWLDTLEMPYKFFENSFWLKGIYEQASARDIGVMLTGQRGNWTISWGPAMDYQA
                     SLLRKGRLVSFFWEHRRYCQSLGANPWKVLQIVGKKSFPWLAPLIAPGDDPALPVLINP
                     DFASKTNVTDHMKACGMDVWGSSTQNAYDIRKDHFNQLYFWNINGTIGTKLSLKHKIWD
                     RDPTNDLRVVRFCLSVPDEQFVQQGVDRSLIRRATARYLPDKVRLNRKRRGVQGADGVF
                     RLMPDWSGLIRELEQMIGDPRTCYYLNAPLLRELLNEIRHRPRPELAFDLKFRVLMRGF
                     IFHKFLSRIS"
     misc_feature    14185..14198
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            complement(14296..>14755)
                     /db_xref="GeneID:76998040"
                     /locus_tag="FLT43_RS18940"
                     /old_locus_tag="FLT43_18940"
                     /pseudo=""
     CDS             complement(14296..>14755)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005550349.1"
                     /locus_tag="FLT43_RS18940"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="FLT43_18940"
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="KAHHVIVLCHTGLKYDREMAKQVPGIDIIVGGHTHTRVDEPELVN
                     GTYIVQDWEYAKSLGRVDLYYHGEDLVHFSGGLLKRRDRCQGRRQGAGKRHNVSCRDER
                     LPDRGR"
     gene            complement(14828..15859)
                     /db_xref="GeneID:76998041"
                     /locus_tag="FLT43_RS18945"
                     /old_locus_tag="FLT43_18945"
     CDS             complement(14828..15859)
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308516.1"
                     /locus_tag="FLT43_RS18945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18945"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_174818158.1"
                     /transl_table=11
                     /translation="MKLQKIFNTEAPNQSTRIILGECSGILNWDDIRMPHMYKLYKVLL
                     LNHWIADEIPMSKDAQQFPNLTPDEQRAFKINISLLAVLDSMQTMFVGDVKRFFTDSSL
                     EAIAAIIAQQEVVHNQSYSYVLSSLVSEQEQKDIFEYWKHDAVLLERNRFIADIYQTFR
                     DNPTPQTFFEALVADLILEGVFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYF
                     FGEVFKQLLRDFPELNTDANRRFVYDTIDRAVQLETNWAHYTLSNIRGIDLRELSDYIK
                     YIANRRLAMMGLEKAYEGVDVNCMPWIKPFSDEALNSTKTDFFEAKSRNYGKVGDDNGF
                     DEL"
     misc_feature    complement(15902..15915)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.08"
                     /tool="antismash"
     gene            complement(15960..18305)
                     /db_xref="GeneID:76998042"
                     /locus_tag="FLT43_RS18950"
                     /old_locus_tag="FLT43_18950"
     CDS             complement(15960..18305)
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678391.1"
                     /locus_tag="FLT43_RS18950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18950"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_087444105.1"
                     /transl_table=11
                     /translation="MLTTNHTVQTVHKPNNRSLAFDAERIMRYGERIMGAYPELDRERW
                     HRGVLAKLRHSHVQASDITQACIMTALELVSVEEPKWKFVAARALLTKLYKEAALHRSY
                     KAYADRPYGDFYKLIKQLADIGIYRQELLEAYTPDQIRELGQAIDPACDELFDYIGLLT
                     LAERYLAVDFEGRTMELPQERYMIIAMYLMHQEPEERRVELAKEAYWAMSNLYMTAATP
                     TMANAGKKVAGQLSSCFIDTVDDSLEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDI
                     RGHKNTSSGVIPWIRQLNNTAVSVDQLGTRKGAIAVYLDVFHKDILSFLDLKLNNGDER
                     MRAHDIFHGVCIPDLFMEAVEKREDWHLFCPHEVKKTLGWTDGNGRPLGLEDFYDEQAG
                     QGQFREKYAEAVATPHLSRITLPAIDIMKRILKSQLETGTPYMFYKDTANRANPNKAHG
                     MIFCSNLCTEIMQNMSPTTIEQEELVLEDGGARIIISKLPGDFVVCNLNSIHLARAVRV
                     LERLVPIQVRMLDNVIDINNIEVLQAQHTNRRYRAIGLGTFGLHHLLALEGIAWESDEA
                     VEYNDYLYEQIHYLAVRASMELAKEKGAYPLFAQSEWENGRYFEQREYTTGTRPGRFVT
                     TEQWNELAAEVKANGMRNAWLMAVAPNGSTSIIAGSTASIDPVYELLSYEEKTTYKIAN
                     PAPDLSDKTMWYYKTAFRLDQNWSIRMTGARQRHIDQGQSFNLYVRPDIRAVDFLNLHL
                     HAWKAGLKSTYYVRSQALTVEECEACSS"
     regulatory      complement(18534..18808)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(18593..18612)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.66"
                     /tool="antismash"
     misc_feature    18807..18824
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    18907..18921
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 22.38"
                     /tool="antismash"
     misc_feature    19050..19063
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.42"
                     /tool="antismash"
     gene            complement(19069..20079)
                     /db_xref="GeneID:76998043"
                     /gene="namA"
                     /locus_tag="FLT43_RS18955"
                     /old_locus_tag="FLT43_18955"
     CDS             complement(19069..20079)
                     /EC_number="1.6.99.1"
                     /GO_function="GO:0003959 - NADPH dehydrogenase activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998043"
                     /gene="namA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019419299.1"
                     /locus_tag="FLT43_RS18955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18955"
                     /product="NADPH dehydrogenase NamA"
                     /protein_id="WP_087444104.1"
                     /transl_table=11
                     /translation="MPQLFEPLTLRGVTIPNRIVMSPMCMYSCHNEDGMVNDWHLVHYT
                     SRAVGQVGLIMIEATAVTPGGRISAQDLGIWSDEHVDGLRRLTDMVHAHGGKIGIQLAH
                     AGRKATVPGIIAPSALRFSEAYETPEEMTLEDIRKTIKAFADAARRAEEAGFDVIEIHG
                     AHGYLINQFLSPLTNQRTDSYGGSADARYRFLSEVIEAVRITWSKPLFVRISANEYAEG
                     GNVIEAYIDYARRMKDQGVDLIDCSSGGVVPHRVEAYPGYQVQYAHAIRQSAGIATGAV
                     GLITEPSLAEEIVRNGRADLIFLGRELLRDPYWPRQAAKQLRQELAPPKQYDRGW"
     gene            complement(20199..21128)
                     /db_xref="GeneID:76998044"
                     /locus_tag="FLT43_RS18960"
                     /old_locus_tag="FLT43_18960"
     CDS             complement(20199..21128)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (34-288). E-value:
                     5.4e-16. Score: 50.9. Matches aSDomain:
                     nrpspksdomains_FLT43_RS18960_Abhydrolase_1.1"
                     /codon_start=1
                     /db_xref="GeneID:76998044"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678387.1"
                     /locus_tag="FLT43_RS18960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18960"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_087444103.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-11, bitscore: 43.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.7e-12, bitscore:
                     46.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSNTFTFTDPEGVRVHVYRWDPEEGQPVRGVIQIAHGMTETARR
                     YSRFAEALTEAGYVVYANDHRGHGRTAERPEDLGYVGEDGFTWMVRNMAQLTEIIQSEQ
                     AGLPVFLFAHSMGSFLAQKYIAEHGDKINGVILCGTNGPRGRELYAGVALTKLIASARG
                     SRHRSKMIDNMAFGGFNRTFRPSRTSFDWLSRDEQEVDKYVADPECGFLSTIGFYRDLF
                     RLLQDIHRPETMQAIPKELPVMLIAGDRDPVGQYGKGIRRLAEMYRELGIREVECILYP
                     EARHELLNEKNRDEVTSDCLSWLRNHTP"
     aSDomain        complement(20265..21026)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FLT43_RS18960_Abhydrolase_1.1"
                     /evalue="5.40E-16"
                     /label="FLT43_RS18960_Abhydrolase_1.1"
                     /locus_tag="FLT43_RS18960"
                     /protein_end="288"
                     /protein_start="34"
                     /score="50.9"
                     /tool="antismash"
                     /translation="IAHGMTETARRYSRFAEALTEAGYVVYANDHRGHGRTAERPEDLG
                     YVGEDGFTWMVRNMAQLTEIIQSEQAGLPVFLFAHSMGSFLAQKYIAEHGDKINGVILC
                     GTNGPRGRELYAGVALTKLIASARGSRHRSKMIDNMAFGGFNRTFRPSRTSFDWLSRDE
                     QEVDKYVADPECGFLSTIGFYRDLFRLLQDIHRPETMQAIPKELPVMLIAGDRDPVGQY
                     GKGIRRLAEMYRELGIREVECILYPEARHELL"
     misc_feature    21080..21091
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     gene            21974..22465
                     /db_xref="GeneID:76998045"
                     /locus_tag="FLT43_RS18965"
                     /old_locus_tag="FLT43_18965"
     CDS             21974..22465
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0033745 - L-methionine-(R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76998045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006678386.1"
                     /locus_tag="FLT43_RS18965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_18965"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_087444102.1"
                     /transl_table=11
                     /translation="MFTPSQYSGQPDQDYPLLHKQLLALIEGEPNLIANLANASALLWQ
                     GLKDINWAGFYLMDESKEELVLGPFQGLPACIRIPLGRGVCGTAAQERRTLVVPDVHAF
                     PGHIACDAASRSEIVVPMMKDGRLVGVLDIDSPLTDRFQEPDREALEKMVEALMKEAVL
                     "
     misc_feature    complement(22740..22758)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.44"
                     /tool="antismash"
     misc_feature    23039..23053
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.23"
                     /tool="antismash"
     misc_feature    23590..23604
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
ORIGIN
        1 agcgatatct gactgaagga gtaagttcat ggagaagtcc cttatcttgg acacagacat
       61 gctgacgaac gaaatgaagt tgattctgga gattattaca agtgatcgtc ccgaggattt
      121 gcgcaaggac aaagccgggc tcttcaagga ctgcaagtgg gatgcatttt tacgccttgc
      181 gatgcatcac cgagtctatt ccgtgctgta tatgcagatg aaggatatgg gcgatgatat
      241 ggtgcctccg gcggtcattc aacgtctgta ccgccaatat tgcgccaata cgctccgaat
      301 gcttcatctg agcagcgaga tcgaacatat cggcaaggaa ttgaccggaa gaggtctgcg
      361 ttgtttattt ttgaagggac ctgtgcttgg ccaggattta tatggaagtg tctcgcttcg
      421 cacctgctcg gatctggatc tcctcgttcc cttggccgaa ttagttcggg cggaaacgat
      481 acttatcacg ctagggtacg agaaagatga ctacattgag tccgtactgg gggactggaa
      541 atggcggcac caccatctga ccttttttca cccggtcaag ggcatcaagg ttgagcttca
      601 ttggcggctg aacccgttcc cgtccaagga accgaaattt aacgagttgt ggctcaggaa
      661 gcgaagaagc acgctgttcg gcagcccgat ctattatttg ggaagagagg atttgttcgt
      721 ctttctcgtg acccacggag cccgccacgg ctggtcgcga ctgcgctggc tgctcgatat
      781 caagcagctt cttaaccaac agccggatca cggccagatc atgaatagat tgaggcgtcg
      841 ccggtgtgtg cgtgccgggg gacaatctgt cgtcctggca tcgtcgctgc ttcaagcgcc
      901 gttagcgccg gaactgcagc agcttgcaag caggcgtaga tcggtgcggc tggcccaggg
      961 cgccatgttc tatctgtcgc agatggttca tctccataag gagccgatac ctgaagaagt
     1021 cggagcctac cataagcgcc atctgttcgc gttaatgccg ctgcggcata aatgcttgtt
     1081 cattctaagc ttcatgatgc cttatcccga ggatgtcaag gtcattcgat tgccgagaat
     1141 gcttcattat atctatattc ccttaaggcc cttcttgtgg gcgtggagga aaagcgtggg
     1201 tgtacagaaa tgaaaagagt actgttcgca tccttcgata tggaggttgg aggagttgag
     1261 agaagcctgg ctggtttgct ggagcatttt gattatgaac gctatcaggc ggagctgatg
     1321 ctgtatcgcc atcaaggcga ttttatgcct ttgctccccg aacaagtccg gttgctggag
     1381 gagcaacgag cctatgccac cttccgcaag tccatcggcg acattatcaa gagccggcag
     1441 ctgctgatcg gcctcggaag gctgaccgca aaagtgcatg ccgatatggc cgggaaagcg
     1501 agagggtgtg cagaaacggg atatcatcag atgcagctga tgtggagata tacccttccc
     1561 ttcctgcccc ggaacaaaca gctctacgat gcggctgtaa gcttcttatg gccccattac
     1621 tacgttgccg agaaagtcga tgcccgcacg aaaatagcct ggattcatac ggattattcg
     1681 accgtggcta cgaatgtgca ctcggatttg aagctgtgga gcaagttcga tcatatcatc
     1741 gccgtatctc cttcatgcag ggaagccttc ttggcaaagt acggaaccct gagagacaag
     1801 gtgacggtca tcgaaaacat tatctctccg gactacatca agatgatgtc cgaggtgtct
     1861 gttgattcac cgatggcagc ggatccgcgc ttcaaattgg tcaccgtcgc ccgtttgtcg
     1921 cacgccaagg gaatcgacca ggctgtcatg gccttgaaga agctgagaga gaaggggctt
     1981 gaggacattg cctggtatgt tgtgggttat ggcggggacg aggagatgat tcgcggtctc
     2041 attgcgaaga atcggctgca ggaggatttc attttgctgg gcaagcagta caatccctat
     2101 cctttcatca agcaagccga tctctatgta cagccttccc gttacgaggg gaaagccgtg
     2161 accgtaaccg aagcccagat tttgagcaag cctgttctga ttacccgcta tcctacggca
     2221 cagagtcagg ttgccgacgg caaggacgga tatattacgg acttatcggt cgagggctta
     2281 gcggaaggga ttgagcattt atatcgagat cggcagctaa gaggccggct cgcggacatg
     2341 tgcagcagga ctcagtatgg caatgcgggc gaactcaata aactatacgc attgttggat
     2401 gacaatggat aggaggcgag gctatggata acatcctgct gctcgacacc tcagtcggtt
     2461 ccttgaataa aggggatgaa atcatcatga aatgcgtgag gcgccaattg tctggtatta
     2521 cgagccaggc caatgtgttt accgtgccca cacatctttc ccccttcggc tggttccagg
     2581 tgatgcgaga ttcattacgt gttcaattct atacaagagc caaatacaag tttgtcggcg
     2641 gaacgaatct attgaccatg gacatgttca cccatttccc gcaatggaat attaatgtgt
     2701 ttaattatcg tccgttacaa ggcagcattc tcctgggggt gggggcgggc aaaggagaaa
     2761 aaataaaacg gtacacgaaa atgctgtacc gcaaggtgtt gtcccatgaa tatgtgcata
     2821 gcgttcgaga tgaacgaacc tggagattcg tcacggattt ggggctcaag gcgttaaata
     2881 cgggatgtcc gacgatgtgg gcgttaacgc ccgagcattg ccaggatatt cccaagggga
     2941 aatcggatgc cgtcgtgttt acgttgacag attacgcaag agcgccccgt caagatcagc
     3001 tactgatcga tcttctgatt agaagctaca ggaaagtata tttctgggtt cagggagccg
     3061 atgattatgc gtattttcat acgttatcga ataccgcaag cattcacgtc attcctcctt
     3121 cgctggaaga atatgaagct gtgctcagca cggatgtcga ctttgtaggc acgcgcctgc
     3181 acgccggaat ttatgcgatg cgtcacaaga aacgttccat cattattgcg gttgacgaac
     3241 gggccagagg aatgagtgag acatacgccc tgaataccgt tgaccgtacg gatctcgccg
     3301 gccttgaagc catgatccat tcggaattcg cgacgaatgt ccggatgaac ctggaggcca
     3361 tccaagcgtg gttggatcag ttcaagcagc ggtaatatcg gtcttgaagg aggaagccca
     3421 tgatacaact gacgcgggaa caaatcaaag taaatcataa ccgtgtggac tatttttttc
     3481 aggtggaccc caggcttcaa aaatacttca gagcaagcaa tcatttattc atgaaatata
     3541 actatgatat ctcgggtctt ccagcaagca tattgtcgat tccgtttgcg gcgaacatga
     3601 tgccgctcgc gtggcttacg gatgcgacgc tgtacgtcga cgaactggat cgttccttct
     3661 atgactgtct tgcggaactg aagcaggcat atcaggagat gttcccccat ttcccgctca
     3721 aggggcaaat caaggtcggg caggtttctt cctatcatta tcaaccggag catgaagctg
     3781 ccgtgctatt tagcggggga ttggacgcat tgacgaccta tatccgtcac cgggataaga
     3841 agcctttgct cattacggag tacggatggc atgaagggga ctgtacagac agcgaggtat
     3901 ggacggcaga ccgtgagcat gcggaagctt ttgcccgcaa ggaagggctc tccaatatcc
     3961 tggtggagtc caactacggc accttcgtct atcctcagcg aatcgaccgg gatttccggc
     4021 gcccgctggg ggacacctgg tggcatggac tgcatcacgg tctggcgatt atatcggctg
     4081 cggttcctgc agcctgcttg ttacaggtga aaacggttta cattgcgagc tcgcatacga
     4141 tcggcaacac gtattcatgt gcttccgacc catcgacgga caatctgatt cgttacggag
     4201 cgggcgatgt gttccatgac ggatacgagc tgtcccggca ggataaagtc aaagtggttg
     4261 tggatcacta tgccgctgcc aatgacaaga ccgccgtccg ggtatgctat cgcaacacag
     4321 aaaactgctg ccaatgcgag aagtgcgtaa gaacgatcat ggggattgcg gcagagggcc
     4381 atgacccgaa tgactacggt tttccggtgc ctgatgagct ctccggtttt ctgaagcggt
     4441 ttttgaagcg ggaggtcaag tttttcacga atatccaaat cgaacggtta tggaagccga
     4501 tccaggagcg catgcgggag aaccctgaca acgtgaagga tcaggatctg ctgtcttggt
     4561 ttccggagta cgattttgtg gcccagcgaa gaaaagaacg gttccgctac cgtgtaacgc
     4621 aatttttccc aatcattaga aggaaagtga gaacgggttt gcagcaaatc cgtgaaacca
     4681 ggtaaaagag caggtacagg gatgagaatt cgaaattcgc tttataacat tttttttggt
     4741 ctgctggggc aagccattag caccataatg ggttttgtcg ttagaacggt ttttatatgg
     4801 acacttggcg ttgagtatct gggagtgagc ggcttgtttt ccgatgtgct catgctcctg
     4861 tctctagcca atctcggttt tgagacggcc atcatttaca gcttgtatca acctcttgcc
     4921 gatcgggacg aggccaggat aaaagctttt atgcatttat ttcgaaaagc ctatctgttc
     4981 ataggtatgc ttgtgctcgt gctggggctt tccctgattc cttttcttga tgttttcatt
     5041 cagggggaaa cgacggtttc tcatatcgaa gtcatctatg tgttatttct gctcaattcc
     5101 gtgtctacct acttcttcgc ttacaaacag gccatcattg tggccgacca gcagcagcat
     5161 gtgatatcgc gaatccatag tgtgtatgtg attgccatga acacgatcca gatcatcgtg
     5221 cttctctgtt cgaaaaacta cattctattc cttgtgatcc aaattggaat gagcgttctt
     5281 agaaacaagt atatttcccg tgtggcagac cgaaagtacg aattcctgag ggagccggtc
     5341 agcactcctt tggacaaagg agagaagaag accttttttc agaacctgcg ctccctgctt
     5401 atgtacaaag tgagcggcgt tgtcatcaat gggacggata atctgattat tgccaaccta
     5461 tttggcgtca tatgggtcgg attgtattcc aattattatt tgattctgac aaccttaact
     5521 acatttgtga gctatttctt ctattctcta acggccagcg tggggaattt gaacgctacg
     5581 gaggataagg agaagaagtt tttcttctat cgtgtgttac gcttggccaa tttttgggtg
     5641 ttcgggctta gtgccgtatg tttgtggaat ttgcttgatc ccgtgattat tttatggctc
     5701 ggaggttctt ttgtcctcgg caaggagacc ttgcttgcga tcctgctcaa tttttatacg
     5761 acggggatgc aaaatgcttc gaccatgttc cgggatacga cgggcatgtt ccgaagggga
     5821 aggtacagcc cgttgatcgc agcggcaatg aacatcggat tatcgattac gcttgcacgc
     5881 ttcatcggga tgccgggagt attcctcgga acagtcatta gccgattgct aacctatttt
     5941 tgggttgatc cttatttgct tcataagcac gtattcttgc aaccgctgcg cccttatttt
     6001 acccgttacg cactgcatgc cgtgttagtt cttctggcgg catccttatg cggctggctt
     6061 gcaggattac tcacgctgcc gctgttatgg gatatcgccg tcagggtcct gctgtgcctg
     6121 tccgtaacga acctgatctt ctatgtgtgc tttcgcaaat cgagcgagtt tatctactta
     6181 acgaacatag ccaaggcgaa tatgggaaag ctgccgatcc ttactaaatt caatccggtc
     6241 atacggagag aggagacaag gtaatggcca ttttgatcac gggtggcgcc ggttatatcg
     6301 gaagccatac ttgcgtagaa atgctggagg cgggatatga tatcgtcgtt cttgataatt
     6361 tctccaacag ccatccggaa gcgattcgtc ggatttcgga tattacgggc aaaggatttg
     6421 ctttttatga agcggatctt ctcgacgagc aacgcttgaa tcggatattc gagggacatc
     6481 gcatcgatgc cgtgatccat tttgccggcc tgaaagcggt tggggagtcg gttcaggtgc
     6541 cgcttgaata ctaccatacg aatcttacca gcacgctggt tctgtgcagg gcgatggcca
     6601 agcatggcgt gtacagcctg gtattcagct catccgcctc ggtgtatggg gtaccggaat
     6661 gtgttcccat ttcggaggaa gccagccttg gggcggtgag tccctatgga agaaccaaac
     6721 aaatgattga gcaagtactg caggatctgg cttcttctga cccgagatgg ggaatttcca
     6781 ttctcagata tttcaatccc gtcggtgcac ataaaagcgg aaagatcgga gagagcccta
     6841 atgggacgcc taacaattta atgccgttta ttacgcaagt agctgtgggg agattgccgt
     6901 cgcttaaagt atacggctcc gattacccta caaaagacgg tacgggaatc cgagattata
     6961 ttcatgtcgt ggatttggcg caaggccatc tgaaagcatt ggagcatttg gatcatataa
     7021 atggggtcga attttacaat ctgggtacag gccgggggtt tacggtgctg gagatgatcc
     7081 attccttcga gaaggtgtcg gggattcaga ttccctatga aatcgtgggg cgaagaccag
     7141 gggatatcgg gatatgctat gctgatccga caaagtccca tataagcctg gggtggttcc
     7201 cgaaatacgg cattaccgac atgtgtgaag atagctggaa ttggcaggtt cataatccgc
     7261 aaggttattg cgagaggatc acggccgggt aatcatcgaa ttcgacaaaa ctagtgctcc
     7321 agagacgaca tactatgaca ccatggaacg tcaaatgtcg tgtataatac tacttaataa
     7381 gtatatatta ggaaacgatg aaatgcgcct tttttgtctg ggcactttag gcgtgtggag
     7441 ttagtggtgc aaccggccga gtaaattcgg gaggcaatgc aatcatggtt gaagcggtta
     7501 caggtaacaa tgaacaattg gacaaggatt gggtagctat tattttaact gcacgacaaa
     7561 tgggcctttc cattgcggac attcgtaaac ttcttcgcga ttttcaggca cagtctgatc
     7621 ctgaatggcc gctccatgtc aattcagaag cataactcac gattgttgac attatcgaaa
     7681 agaaatctcc ttcgttgagg catgtttaca gataacgcgc ggtgaactca acaatcggag
     7741 atttctttat tttgggctgc gtcaacgcta gggagcatca tgactcttcg cgtgttagct
     7801 tccacttatt atattccaga aattctttga attgctcttt acttacgcca gaagccatcg
     7861 cttcttttac gagattagtc cattcttcgt ccaacacctc agcttcattc gaagcttcct
     7921 tgtcttgcag cagctcctca actgagaccc cgagaataac actaatcttc tccagaaatt
     7981 gaatggaagg attctgctga attcctcttt caattgagct taaataggat tttgcgacac
     8041 ctgctctttc ggagagttct gacagtgagt aatttttctt ccttcgaagg atttgaatcc
     8101 gttctccgat catgatttaa cctccgtgta tacatctgct tgtccctatt atatccgatt
     8161 tcccccacct ccgaaagcgg ctacagcgta tagacgttaa caggctgcgc ctcctgattt
     8221 tgtaaaagat ttgcaaatat gctctttttt tctgaggata atgacaaaaa ggttccctgt
     8281 tcagccaatt tcccgtcatg tatgactaaa atttgttccg cgttttggat ggtggacagc
     8341 ctatgggcaa ccacaatgac cgtaatgcga tccttcaacc gatgtaaagc ggtcagaatc
     8401 tttttttcat tctccgtatc cagtgcgctt gtcgcctcat ccagaacaag gatagaaggc
     8461 tgccggatga tggctcttgc caggaccagg cgctgccgtt ctcctcctga caaacgaatg
     8521 cctcgatctc caatgagcgt ctccaattgg tgaggaagct tgcgtacaaa ttcagctgcc
     8581 gaggaaaaat cgagggcttc ccacagttcg ttctccgtgg cactcggttt caccatcaac
     8641 aggttttctc ttatggtcgc attataaaga aacggatcct gcgccacata cccgatggag
     8701 cgtctgtacg cgagcaggtt gtcattcgtg atcgctatgc catccacgag gatttgaccg
     8761 gattcaggct gcatcaggcc cataaggata tcgataaacg tgctcttgcc ggcccctgat
     8821 ttgccaacga tagcggtcat cccttgggct ggaatatgaa cgctgatatt ttgcaaagca
     8881 tacacaggca gttgcggctg atagcgaaac gaaagatttc tgacttcgat tccttgcata
     8941 acgaaccaat ggccaggtcc cggagcgggc gattcggtaa gcgtaatcgc ctgatctgcg
     9001 gccaatttgc agtcacgctg caattgctga agagccttga aggccgggat ggtcgaggct
     9061 aattgttcca gcttggactg gaggctggta aatctcggcc acaacctggc aaagagcagg
     9121 ataacgatca ataaagacgg cccctcactc ggaaaaaaac gaaatgacgt aaagataaat
     9181 ccggcaataa gcagtgagga cgctatttta tacaacagct gggaattcag ccgtagccgc
     9241 acataatcca gctgctcttg catggttcct tcggtaagct gctggtgcca ctccaagcgg
     9301 gagggttcca ggttattgct ctttatatct ttcattcctt gaagctggtc cgtgattcct
     9361 gccaaataag cttgggcgag cttggacgtc tggctgccga gctgcttgga tttgcgaata
     9421 aatccgcggg aaagaaaagc aagcatggct ccgcaggcaa taacgaacag cgttatcttc
     9481 ggtgagatcc agaaggcgaa aataatctga aggagggtaa acaaggcaga tgtaatgaat
     9541 tggagaagca gactgattcc ccccaagact ctggcggttt cgatcgtaag ggcattcacc
     9601 agatcggaag ttctgcgatt tataaaaaaa ggccattgcg ctcttagaag agcactgtaa
     9661 ttctcgtaac gcagttgtcg gctgaaatgt tgctctatct cggcattgcg gaccgtaacg
     9721 gctcgatgaa tgaggttctg agtgacgaca atcagcaggt atacggttag aatgatggcc
     9781 agggaagagg cctgcggcaa gctgtgcagg atgttcaaaa accgcagcct gttctcccaa
     9841 gccggctctg acaacagaac accgccaacc gtaagcatgg ggatgagcag aagaaatgtc
     9901 atgccctcca ggagactgct gatcaccatg ccgataatgt tgatgcttaa ttgtaaccct
     9961 gccgtttgat gaagccgctt catgtacaga ataatcgaat tcatgggtct gtccctgcgc
    10021 tcttcgcgaa tttctccacc acgacgaact gcttcatcat ctcggcgccg gtaatgtata
    10081 tcgagccgct gcggagccag gcgtgtgcga tcagttcacc gtttttattt ttcccggtcc
    10141 ccaaatataa cgtgctgtgc aggtttcttt tttcaagcat cttcatacct gccatcgccc
    10201 ttaccaagca tttgctctcc cagaaagtat gccggctcac gatctggatc gcgctccgaa
    10261 tatgcttcat ggttttcgtg tgcgacggat catggacttc tggcgtttcc atggatcgtc
    10321 tccccagcag aggcgagatc ttcgcgaacg ggaaatacaa aagaatgcgc gcccacccca
    10381 aataaagaaa agcttccgcg aataaaagga atgtcttccg atctgatagg cataaccata
    10441 tccatcttcg caaccggttc atagccgctt cacatgccgt attaagccct catgctccaa
    10501 atccgagagg aacaggagaa tgtcttcctc gcattccgac gactctacct catatgcgga
    10561 taaaatggat cggataatat gttccgcctt cacgggcgtg ataagcatgt cccagatctc
    10621 gcctccaagc gtaccgagat tatagtattt tcccttctgg acgcttaaca tcactttctc
    10681 gccggccata tcgctaacga tatggccctc gcattgaaca agcgtatcga caggggtgat
    10741 cgaatgaagt ttgctcattg gtcattctct ccttgccgga taatgtttaa gatatgcgat
    10801 gtcagatcaa gcgtgctgaa tccaaccatg ggacggtgca gacggtacat cccgacctgg
    10861 cgaatgaagg atgacagggt cttgaagtgc cattccatca atcccagcgg ctgtaccaac
    10921 aaattacggt acgtatggtg aaagaggacg cgaaagcgct ccatcccctg gatcggcgca
    10981 atatgagtgg ctgcatccca gggaaccagc tcaaagatac ttgccaacgg aagtggtttt
    11041 tcatgaaagt tggaccccgc gggcacggca aatttcgtat tacgctcata aagcggggtg
    11101 taattggcat tgtccattcc catgtgcttc aatgtgtcca cccataattt ttgctgcggg
    11161 taagatggaa caacccaagg agagcctcga gtcatcacga cgggaataac atcatcgcta
    11221 agcagcggat atccctcgga catcaggtgc aaggccaagg tggatttgcc cgccccggat
    11281 tcgccgataa tggcataggc tttcccgtca atagctacgg cgctgccgtg caaaggcata
    11341 attttgcgct gcagcaatag aatgcccata caagtcccca gaataaaaag ccgaacccaa
    11401 ttctcttccg cctgatcgaa cggagagacc aggatggagg aggcatcctg taccgcatat
    11461 atggcagccc caggtacccg aaacataacc gtacggccgt gatccagaat agcgaagttt
    11521 ccatagaaat gaatggagct gttccagaga ggctgcaagt ctgtccgccg taccgtaatg
    11581 ttgtccagag gctcgcgctc gccagccaga ggcagttccg gtaatacaaa gtcgctctca
    11641 atacggaagc caaaagcttt ataatggtca gtccttaccg ctgctcgttc ggtcatgctc
    11701 atctctccaa gagtttgtaa atttgagaac aggggaaccc ttatacccgt tgagaagtat
    11761 aagggtaccg caccagtaac cgcattcatt aagccaattg tctagctatc catcggatcg
    11821 taatgcacat cttcatccgg gtccggctgg aaagcatccg gcgtagagag acccggtcca
    11881 gccatggtct gatgaacatc caacacttca agggatggct tgctgtactg ctttttcatg
    11941 gttacacctc ctttcaagag attcttgaca ggaatttatg aaagatgaac ccgcgcatca
    12001 gcacgcggaa cttgagatcg aacgcaagct ccggccgcgg gcgatggcgg atctcgttca
    12061 gcagttcacg aagcaggggg gcattcagat aataacaagt tcgcggatcg ccaatcatct
    12121 gttcaagctc acggatcaat ccactccagt caggcatgag cctgaacacg ccgtcagcgc
    12181 cctggacgcc gcgtcttttg cgattcaatc tcaccttgtc ggggaggtag cgggcggttg
    12241 ccctgcgtat gagtgaacgg tcgacgcctt gctgaacgaa ctgttcatca ggcaccgaca
    12301 gacagaagcg gacgacccgc agatcattag tgggatccct gtcccagatt ttatgcttaa
    12361 gggaaagctt tgtgccgatc gttccgttaa tattccaaaa gtacagctga ttaaaatgat
    12421 ccttgcggat gtcatacgcg ttctgagtcg atgatcccca gacgtccatg ccgcaggcct
    12481 tcatgtggtc ggttacattg gttttgctgg cgaagtccgg gttaatcaag accggcagcg
    12541 caggatcgtc tcccggagca atcagcgggg cgagccaagg aaagctcttt ttgccgacga
    12601 tttgaagcac tttccaggga ttcgccccaa gcgattggca ataacgtctg tgctcccaga
    12661 agaacgacac gagacgcccc ttccttagca gactggcttg gtaatccatg gcgggccccc
    12721 aggaaatggt ccagttcccc ctctgtccgg tcagcataac cccgatgtcc cgggcagagg
    12781 cttgttcata gattccttta agccaaaaag agttctcgaa aaatttatat ggcatctcca
    12841 gcgtatcaag ccattcgtct atgacggagt aagggttgct tgacggataa ctggatacat
    12901 tcatctcgat attgcctaca tgctccgccg tggaccgtat gtattctctt tcatccgcaa
    12961 aacggctgca tgaagtgaaa tcggaaaagc cttcgatcgg ataatagctg aaggtataga
    13021 gagacttgtt gttggctttc aacatcggtg cggcaaagct tacaaccgaa ccggaatcaa
    13081 gtccgccgct tagatgtgct ccaacctggc ggaacgttct taaccgagcc tgaaccgcag
    13141 tctggaaaac atcccggagc gcttcctcgt attcctcgtt gcttgtaagc acaagcttct
    13201 cagtatgctg cagacggcaa tattgttgaa agattacttt cccattggca acgaaaatgg
    13261 aatgcgaagg ggggatctgc ttgatggatt gatacacggt agaaaaagaa tctacggcgt
    13321 ctgtcgtgat ggggatagca aggaattggg aaatccagtg ttcgttcaag tctcttttca
    13381 catgtggcag cgtaagcagt ggttccatga ttgtacagaa tgagaacagt tccggggatt
    13441 gatgaaagta aagggtccgt gttccggaaa aatcccttgc gccaaacatc gtgcgatccc
    13501 tgccatccca aatgatgaaa gcgaaatccc cgacgagatg tttgggcata tcatggcccc
    13561 atttcatata cgcttggaga ataagctggc tgtccgttat ggtctgtcga gcctgcttgg
    13621 atagttgcag ctggtctgct aattcgtccc ggttatcaat aatcgcatcc gaagtaatgg
    13681 cgagcgatgt aaccggatca tagcagggca ggacctcgtt gatggattgc ggggtaatgc
    13741 actgctggag gctccccaga aataaggaac cgttactcca gctgcttaca taatcagcgg
    13801 gaaagcgccg caacgcatcg atcatttgtc tgccaagtcc gggttccagc ttatcgtgtt
    13861 gaaggtgata aatgcctgct actgcaccca tcatcgttct cctccgaata cacgtttttt
    13921 gttcttatta aagaacgaga taaacttaat atgttcccaa taaagaacac aaataaagag
    13981 taacatccct ctttaaggat tgtcaaccat ggttgaaaga atgagaaggg acgggaactg
    14041 cacatgtaga aatagatgtg aacatcagcc tcgtctcggc cagtgcatcc cgtgtgagtc
    14101 ttcccattcg aggtggcgca atatgtcgcc ttaacccctc ttaggatgcg gatgccctct
    14161 atcttctctg ggaagatggg ggcttttttt catcaaaaaa agagccgcgc aggcacgggg
    14221 aaatacgtgc ggcgtacgcg gccctttgaa gaggggcttg attataatag cttctatacg
    14281 gaatgggcaa gacagttact ggcgaatgcg ctgctcggtc ctgcttgtaa tctctttctt
    14341 cgccttcatg tactgttcga ctacttcata gagcgtgacg cccgtatcaa gcgatttttt
    14401 gttcatgaac atggagtatc cgtcaccgcc cgcgatcagg aagtcgttcg tcgcgacacg
    14461 atacgttgtg tctttttcca gcgccttgcc gcctgccttg acatcggtca cgccgcttta
    14521 gcaagccgcc ggagaaatga accagatctt cgccatgata gtacaggtct acccggccca
    14581 gcgacttggc gtattcccaa tcctgcacaa tgtatgtgcc attgaccagc tccggctcat
    14641 cgacccgagt atgggtgtgg ccgccaacga tgatatcgat gcccggcacc tgcttcgcca
    14701 tctcgcgatc atacttcagg ccggtatggc agagcacgat gacatgatgg gccttgcctc
    14761 ataccgttca tattatgcgc tggcaatagg gatacatgcg cgggcgggtg cccggcaaca
    14821 tgcctgctta cagctcgtcg aagccgttgt catcgccgac tttgccgtag ttgcgcgatt
    14881 tggcttcgaa gaagtcggtc ttcgtcgaat tgagcgcctc gtcggagaag ggcttaatcc
    14941 aaggcatgca gttcacgtcg acgccttcat aggccttctc caggcccatc atagcgaggc
    15001 ggcggttcgc gatatattta atgtaatcac tcaactcgcg cagatcgatg ccgcgaatat
    15061 tgctgagcgt ataatgcgcc cagttcgtct ccaactgcac ggcccggtca attgtatcgt
    15121 agacgaaccg gcggttcgcg tcggtattca attccgggaa atcgcgcagc aactgcttga
    15181 acacttcgcc gaagaagtag cagtgctggt tctcgtcgcg ctggatgtac gagatcatct
    15241 ggctcgtcgc catcatcttc tggtcgcgcg ccagattgta gaagaaggcg aacgtgctgt
    15301 agaaaaatac gccttcgaga atcagatcgg cgacgagcgc ttcgaagaac gtctgcggcg
    15361 tcggattgtc ccggaatgtc tggtaaatgt ccgcgatgaa gcggttgcgc tcgagcagca
    15421 cggcatcatg cttccaatat tcgaaaatat ccttctgctc ctgctccgac acgagcgagg
    15481 acagcacata agaataagat tgattgtgaa cgacttcctg ctgggcgata atggccgcga
    15541 tggcctccag ggaggaatca gtgaaaaacc gcttcacatc gcctacgaac atcgtctgca
    15601 tcgaatcgag caccgccagc agcgagatat tgatcttaaa ggcgcgctgc tcatctggcg
    15661 tcaggttcgg aaattgctgg gcgtctttgg acatcggaat ctcatcggca atccaatggt
    15721 tcagcagaag caccttgtac agcttgtaca tgtgcggcat ccggatatcg tcccagttca
    15781 agatgccgga gcattcgccc aaaataatgc gggtcgattg gttcggcgcc tcggtattga
    15841 atattttttg cagtttcagc tcgcgatcga gtaaagtcat cattttcttc ctttcctcac
    15901 attatcatca ttctatctgc cgcccggcga gagctccatg cggcgctgct tcacttcatt
    15961 taagagctgc acgcttcgca ttcctctacg gtcagcgcct ggctgcgcac gtagtaggtc
    16021 gatttcaagc cggccttcca tgcatgcaga tgcaggttaa ggaaatcgac ggcccggata
    16081 tccggacgga cgtacaggtt gaagctctgg ccttggtcga tatggcgctg gcgggctccc
    16141 gtcatacgga tcgaccagtt ctgatcgagg cggaatgccg tcttgtaata ccacatcgtc
    16201 ttgtcggaca agtccggcgc cggattggcg attttgtacg tggtcttctc ctcatagctg
    16261 agcagctcgt ataccggatc gatgctcgcc gtcgagccgg caatgatcga ggtggagccg
    16321 ttcggcgcga ccgccattag ccaggcgttg cgcatcccgt tcgccttgac ctcggcagcg
    16381 agctcgttcc actgctcggt cgtcacgaag cggccggggc gcgttccggt cgtatattcg
    16441 cgctgttcga agtagcggcc gttctcccat tcggactgag cgaacagcgg gtaagcgcct
    16501 ttttccttcg ccagttccat gcttgcccgc accgccaaat aatgaatctg ctcatagagg
    16561 tagtcgttgt attccacggc ctcatccgat tcccaggcga tgccttccag cgcaagcaga
    16621 tgatgcagcc cgaaggtgcc gagcccgatc gcgcgatagc gccggttcgt atgctgggct
    16681 tgcagcactt cgatattgtt aatgtcgatg acgttgtcga gcatccgcac ttggatcggc
    16741 acgaggcgtt cgagcacccg cacggcgcgt gccagatgaa tggagttcag gttgcagacg
    16801 acgaagtcgc ctggaagctt gctgatgatg atgcgggccc cgccgtcctc cagcaccagc
    16861 tcttcctgct cgatcgtcgt cggcgacata ttctgcatta tctcggtgca cagattggag
    16921 cagaagatca tgccatgcgc cttgttcgga ttggcccggt tggcggtatc cttgtagaac
    16981 atataaggcg ttccggtctc gagctgggat ttgagaatac gcttcatgat gtcgatggcc
    17041 ggcagcgtaa tgcgcgagag atggggggtc gccaccgcct ctgcatactt ctcgcggaac
    17101 tgcccctggc ctgcctgctc gtcatagaaa tcttccagtc ctagcggacg gccgttcccg
    17161 tcggtccagc ccagtgtctt cttcacttca tgcggacaga atagatgcca gtcttcgcgc
    17221 ttttcgaccg cttccatgaa cagatccgga atacagacgc catggaaaat atcatgggcg
    17281 cgcatgcgct cgtcgccgtt atttaatttg agatcgagga aggacagaat gtccttgtgg
    17341 aacacgtcca gatagacggc aatggcgccc ttgcgcgtgc cgagctggtc gacgctcacc
    17401 gcggtgttgt tcagctggcg gatccaagga atgacgccgg agctcgtatt tttgtggccg
    17461 cgaatatcgg agccgcgcgc ccgcactttc ccgagataga cgccgatgcc gccgcccatc
    17521 ttgctcagcc gggccacgtc ggtattcgaa tcgaagatac cttccagcga gtcatccacc
    17581 gtgtcgatga agcagctcga caattggccg gcgaccttct tgcccgcgtt cgccattgtc
    17641 ggcgtcgcgg cagtcatata gagattgctc atcgcccaat atgcttcctt ggccagctca
    17701 acccggcgct cctccggttc ctgatgcatc aggtacatgg cgatgatcat atagcgctcc
    17761 tgcggcagct ccatcgtgcg cccttcgaaa tcaacggcca aataccgctc cgcgagagta
    17821 agcagcccga tatagtcgaa cagctcgtcg caggccggat cgatcgcctg gcccagctcg
    17881 cgaatctgat cgggcgtata ggcctccagc agctcctgac ggtagatgcc gatatcggcc
    17941 agctgcttaa tcagcttgta gaagtcgcca tacgggcgat cggcgtacgc cttgtagctg
    18001 cggtgcaaag ccgcttcctt atacagcttc gtcaacaggg cgcgcgccgc gacaaacttc
    18061 cacttcggct cctcgacgga gaccagctcc aatgcggtca tgatgcaagc ctgcgtgatg
    18121 tcggatgcct gaacatggct gtgacgaagc ttggccagga cgccccggtg ccagcgttcc
    18181 cggtccagct ccgggtaagc gcccatgatg cgctcgccat aacgcatgat gcgctccgcg
    18241 tcgaacgcga gcgagcgatt attcggtttg tgtacggtct gaacagtatg attggtggtt
    18301 agcatccgta ttcctcctcg aaaaagagca ataaaaatag ccgtcccttc gcgagaacag
    18361 ctcaggacgg catggcaaag ccgtatgtat ccgggggctt cttatcatgg cggctgtgca
    18421 tcactaggac aaggcgcagc tcccccctct aaccacgcag ctgcaatcgc ccgccgaagg
    18481 cggtaacagc gcagcgcgcg gcctgaacac gttccctatt ccgcgtaggg taatgaatgt
    18541 gcggcgatac aggcaggtct cctggctcga agccgaatac ctcggcagcc ttcccgggac
    18601 attcgtccca gtggacatag aaaaggccgc tctctacaga gcgcctgttc tgtcgggtac
    18661 ttgctgccgg aacggagagg accgatgttc cggcagcgct tcttacagtg gcgggaccgc
    18721 gacggattcg caccgtcttc cctattaagc cggggcccga cgcgcatcgc ttttgtcgaa
    18781 ccgcagcacc tgtatcgttc aatatgttgt tatactcatg ataatatact acaacatatt
    18841 gggtaagtaa ataggtttca ggtgatattc ctcataagaa aatgacagga tttgagacaa
    18901 ttccgagggc tgtccggacc ttaaaaatgt tcgggatcgg agaggtccgc tcccgcactt
    18961 gaacggcagc ggcggattgg ggcgaagata atgcaagcag gcgaggccgc tggtgcggcc
    19021 ccgcctggaa taagtgagat tcaagatgca atgattatta taaatggatt accagccgcg
    19081 atcgtattgc ttcggcggag cgagttcctg gcgcaattgc ttcgcagcct ggcgcggcca
    19141 gtacggatcc cgcagcagct cgcggccgag gaagatgaga tcggcccggc cattgcggac
    19201 aatctcttcc gccaaggacg gttcggtaat cagcccgacg gcaccggtcg cgatgccggc
    19261 tgattggcgg atcgcatgcg catattggac ctgataaccc gggtacgctt cgacccgatg
    19321 agggacgacc ccgcccgagc tgcagtcgat caggtcgacg ccctggtcct tcattcgccg
    19381 cgcatagtca atgtatgcct cgatcacgtt gccgccttcg gcatattcat tggccgagat
    19441 gcgtacgaac agcggcttcg accacgtgat gcgcaccgct tcaatcactt cgctcaagaa
    19501 gcggtagcgg gcgtcggcgc tgccgccgta gctgtcggtc cgctggttcg tgagcgggga
    19561 caggaactgg ttgatcaaat acccgtgcgc gccgtgaatc tcgatgacgt cgaatccggc
    19621 ttcctccgcc cgccgcgcgg cgtcggcgaa tgctttgatc gtcttgcgga tgtcctccag
    19681 cgtcatctcc tccggcgtct cataggcttc gctgaagcga agcgccgaag gggcgatgat
    19741 cccggggacg gttgctttgc gcccggcgtg ggcgagctga atcccgatct tgccgccgtg
    19801 cgcgtggacc atgtcggtca ggcggcggag tccgtctaca tgctcgtcgc tccaaatgcc
    19861 cagatcctgc gcgctgatgc gtccgccagg ggtgacggcg gtggcctcga tcatgatcag
    19921 gccgacttgt ccgacggcac gggacgtata gtggaccaga tgccaatcgt tgaccatccc
    19981 gtcctcattg tggcaagagt acatgcacat cggcgacatc acgatacgat tcggtatcgt
    20041 caccccgcgt aacgttagcg gttcaaataa ttggggcatg gctatccctc caaagaatca
    20101 tgttcgagat tgtatttccc aattccatta tacccctcca agtatgcagg aacaaatcga
    20161 ccgttcacgt cgaaggatat tccttgatgc agcaatgatt acggcgtgtg attccgcagc
    20221 caagagaggc agtcagatgt aacctcatcc cggttcttct cattcaggag ctcatgccgc
    20281 gcctccgggt acaaaatgca ctcaacctcg cggatcccga gctcgcgata catctcagcc
    20341 agccgccgta tgcccttgcc gtattggccg accggatcgc gatcgccagc aatgagcatc
    20401 accggcagct ccttcggtat ggcctgcatc gtctcggggc gatgaatgtc ctgcagcagc
    20461 ctgaataagt cccggtaaaa gccaattgtg ctcaaaaatc cgcattccgg gtcggccacg
    20521 tacttatcga cttcctgttc atcccggctc aaccagtcga aggaggttcg gctcggccgg
    20581 aacgtacggt tgaagccgcc gaatgccatg ttgtcaatca ttttgctgcg gtggcgggag
    20641 ccgcgagcgg aggcaatcag cttcgtcagc gcgactccgg cgtacaattc gcgtccccgc
    20701 ggcccgttgg tgccgcacag aatgacgccg tttattttat cgccgtgctc cgcaatatat
    20761 ttctgggcca gaaaggagcc catgctgtgc gcgaacagaa ataccggcag cccggcctgc
    20821 tcagactgaa tgatctcggt caattgcgcc atattgcgga ccatccatgt aaagccgtct
    20881 tcgccgacat agccgaggtc ttcgggccgt tccgcggtcc ggccatgccc gcggtggtcg
    20941 ttggcgtaga caacgtagcc cgcctccgtc agcgcttcag cgaagcggct gtagcgtcgg
    21001 gccgtctcgg tcatgccgtg ggcaatctga atgaccccgc gcacgggctg cccttcttcc
    21061 ggatcccagc ggtacacatg gacgcgaacg ccctccgggt cggtgaacgt gaacgtattg
    21121 gataacatat agaacgcctc ccgtaatgga tcggcgataa gctgcggcgg caggggagca
    21181 gccagcagcc tattgccggt tcgtcaggtc cgcttctctc gttgcgctca agggacctta
    21241 tatcattatc ttccattata tcttcggaca gggaaggaaa tccatgattc tgattcgtgc
    21301 gcattctctg attgcggttt tttggagcac ttctgatact tgtcggatgt ctttctcact
    21361 ccttttgccc aatatcccat ccgctcagtc ttgttttcat ttgttgtagc attacgtatt
    21421 cttttgtgta gtctcccagt cgttcaggta acatatattc ctcgaaacaa taccctacgc
    21481 tcaatctccc actcggtcag gatgaaacta tccgctcggt ctgagcccgt ctggttcgga
    21541 accgcttggt ctgaacctgc ttggtctgaa cctgcatagc ctgaacctgc ttattctgaa
    21601 actgcttagt ctaaaatcat tcgtttctga gctatgggga tatccgttat aagagggcta
    21661 gagaggggtg ctgagtttcc tgatcaccgt gaatatattt tgataagaga tatgtgcggg
    21721 atcgagaggg tttcgggcct ttctgaataa cagtaggatc gttcatagag gcctgtatgg
    21781 tctataaaag gttactggct ctcctgagcg acgggaatat tggtcataag aagcaaatga
    21841 agatggagag gtaatggaaa agagtggtga tacaggcgtt gcggcgctga gcgcctcttc
    21901 gcggcagccc ccagatgtga tacgatggta cataatcgta acaagaaata ctgtgcaatc
    21961 aggaggcctg ccgatgttca caccgagcca atattccggt cagccggatc aggattatcc
    22021 gctgcttcat aagcagcttc tcgccttaat cgagggcgag ccgaatctta tcgccaacct
    22081 ggccaatgca tcggccttgc tctggcaagg cttgaaggat attaactggg ccggattcta
    22141 cttaatggac gagtccaagg aagaactggt gctcggcccg ttccagggct tgccggcctg
    22201 catccgcatt ccgttgggac ggggcgtgtg cggaaccgcc gcccaggagc ggcgaacgct
    22261 cgtcgtcccg gacgttcacg ccttcccggg ccatatcgcc tgcgacgcgg catcccgttc
    22321 cgagatcgtc gtccctatga tgaaggacgg acggcttgtc ggcgtgctgg atatcgacag
    22381 tccgcttacg gaccggttcc aggagccgga tcgggaggca ttggagaaga tggtcgaagc
    22441 cttgatgaag gaagcggttc tgtaatctca tattgtaatc gcatatgggc agcgtgatcc
    22501 ggaatggacg cgctgttttt ttgtgacatg aggcgagatt gtgaagtcga tgcgatattc
    22561 atgattttga aatatttgtt gtgatcgtac gcactcggcg gcgctttccc atttagtatg
    22621 ttggaaatag aaatccattt tgacaggggg aagcgcgaat gttctgtcat caatgcgagc
    22681 agacgccgac gggcggctgc caggttgtcg gagtgtgcgg caaggacgag acgattgcca
    22741 gtctacagga tacaatcgtg tttgcgttga aaggcatcgc agcgtatgcg acgcatgcgc
    22801 ggcagttggg ctatgtcgat gaagaagttg acgcgattac gcatgaagcg ctctatatga
    22861 cgttgactaa ctccaatttc aacttacagg agcatctgga catggcgatg aaggtcgggg
    22921 gcgcggcgat ccgcattatg gatgtgctgg atcgggccca tacggagcat ttcggcgttc
    22981 ctgtgccggt taccgtcccg cagaacaaga tagagggcaa gtctatcgtc gtgacagggc
    23041 acaacttgta tgcgctggag gaattgctga agcagacgga gggcaagggc atcaatattt
    23101 acacccattc cgagatgctt ccggcgcacg gctacccggc attgaagaaa tatccgcatt
    23161 tgaaaggcaa tatcggcaaa gcctggtatg accagcgccg tctgttcgag caatatcctg
    23221 gcgccatcct tgcgacgacg aactgtgtca tgccgattaa ggggacctat gccgatcggt
    23281 tcttctccta tgacgtggcc ggactcgagg gcgtgaccaa gatcgtgaac gacgatttct
    23341 cgccgttgat cgagcgtgcg ctggcgctgc ctgcggcgga tgtggagagc gagcagacat
    23401 tgacgacggg ataccaccac gagacggtgc tcgggctggc gccggaaatt attcaggccg
    23461 ttaaggatgg caagatcaag cggttcttcg tcatcgcggg ctgcgatgcg ccaggcaagg
    23521 gcggcgagta ttaccgcgag ctcgcgacat cgctgccgaa cgataccgtt attttgacga
    23581 cctcttgcgg gaagttccgg ttcaatgacg tcgattacgg tacggtggcg gatacgggca
    23641 ttcctcgtta tatcgatctg gggcagtgca ataattccgg ctccacggtc aagatcgcgg
    23701 ctgcgcttgc ggacgccttc ggttgcagtg tcaacgaact gccggtgtcg atcgtgctat
    23761 cgtggttcga gcagaaggcg gttgcgattt tgcttggctt gttcaagctg ggcatccgtg
    23821 atattcgcat cgggccgaag ccgccggaat tcatctcgga aggcgtgatg aacgtgctga
    23881 ccgatctgtt c
//
