LOCUS       NZ_CP041405            20249 bp    DNA     circular CON 07-APR-2024
DEFINITION  Paenibacillus thiaminolyticus strain NRRL B-4156 chromosome.
ACCESSION   NZ_CP041405
VERSION     NZ_CP041405.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus thiaminolyticus
  ORGANISM  Paenibacillus thiaminolyticus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Paenibacillus thiaminolyticus NRRL B-4156
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6612542)
  AUTHORS   Hehnly,C. and Zhang,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2019) Institute of Personalized Medicine, Penn
            State College of Medicine, 500 University Dr, Hershey, PA 17033, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2018
            Assembly Method :: Canu v. 08/2018; Pilon v. 08/2018
            Assembly Name                     :: PSU_Pthia_1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 60.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007066085.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 14:58:54
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,886
            CDSs (total)                      :: 5,776
            Genes (coding)                    :: 5,673
            CDSs (with protein)               :: 5,673
            Genes (RNA)                       :: 110
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 103
            CDSs (without protein)            :: 103
            Pseudo Genes (ambiguous residues) :: 0 of 103
            Pseudo Genes (frameshifted)       :: 52 of 103
            Pseudo Genes (incomplete)         :: 68 of 103
            Pseudo Genes (internal stop)      :: 17 of 103
            Pseudo Genes (multiple problems)  :: 28 of 103
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:43:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2384019
            Orig. end                         :: 2404268
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP041405.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Schiff/Broach Lab 500
            University Drive Hershey, PA 17033
            Chromosome not circularized.
FEATURES             Location/Qualifiers
     region          1..20249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="7"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..20249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20249
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10249](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10249)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(188..553)
                     /db_xref="GeneID:76996438"
                     /gene="csaA"
                     /locus_tag="FLT43_RS10705"
                     /old_locus_tag="FLT43_10705"
     CDS             complement(188..553)
                     /codon_start=1
                     /db_xref="GeneID:76996438"
                     /gene="csaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005548744.1"
                     /locus_tag="FLT43_RS10705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10705"
                     /product="chaperone CsaA"
                     /protein_id="WP_255321637.1"
                     /transl_table=11
                     /translation="MNAAEEAQPQVAQATIEDFMKLDIRIGTIVEAAPLEKARKPAIQL
                     LIDFGPLGLKRSSAQITVRYTPETLIGRQVAAVVNFPPRKIAGFSSEVLVLGGVPEEGD
                     VVLLRTDEAVPNGTPIA"
     gene            complement(598..2427)
                     /db_xref="GeneID:76996439"
                     /gene="recQ"
                     /locus_tag="FLT43_RS10710"
                     /old_locus_tag="FLT43_10710"
     CDS             complement(598..2427)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996439"
                     /gene="recQ"
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019421568.1"
                     /locus_tag="FLT43_RS10710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10710"
                     /product="DNA helicase RecQ"
                     /protein_id="WP_087444902.1"
                     /transl_table=11
                     /translation="MISMDQARSTLKRVFGYDDFREGQKRIIEYILEGKNTVGIMPTGG
                     GKSICYQIPALMLQGVTLVVSPLISLMKDQVDALHSLGVEAAFINSTQEMGEAGRIVRR
                     AEEGRLKLLYVAPERLESEWFRERAKSLPIAFIAVDEAHCVSQWGHDFRPSYRAIAPFL
                     KELEEAGRPRPLMAAFTATATPEVTEDLIRLLELGEPELVVTGFKRDNLAFAVLRGEER
                     RAFTLNYVRERTHQPGIIYASTRKEVEDLCEMLRKAGLAAGRYHAGMSDEERAHMQEAF
                     LYDDLRVIVATNAFGMGIDKSNVRYVLHYNMPKHMEAYVQEAGRAGRDGEPSECVLLFH
                     PQDILTQKFFIEQSEAAPERKTHEYKKLQAMIDYCYTTGCLQTYMLRYFGEMSDETCGM
                     CGNCKDERESIDITTEAQKIFSCIFRMRERFGVSMVASVLKGSRNKKVVQYGFEKLPTH
                     GEMRHLTEKAIADLIYVLIAEGYLQLSEGQYPVVRLLPPAAEVLKGQRQVTQRVATSLK
                     PKAAGAVDQTIFEQLRLIRRELASKAGVPPYIVFNDSTLREMAERMPTTEAEMMLVKGI
                     GEAKLKQFGEPFMAFFRQREEESARLDAQEEWA"
     misc_feature    2459..2475
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.99"
                     /tool="antismash"
     gene            2803..4311
                     /db_xref="GeneID:76996440"
                     /gene="rlmD"
                     /locus_tag="FLT43_RS10715"
                     /old_locus_tag="FLT43_10715"
     CDS             2803..4311
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008649 - rRNA methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996440"
                     /gene="rlmD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009226105.1"
                     /locus_tag="FLT43_RS10715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10715"
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="WP_244194382.1"
                     /transl_table=11
                     /translation="MNERRTGTDRSHRGSNPKERAGWKKGPRPGASGARPRVTDASAEQ
                     VKSGDRIVVTIKRIGINGEGVGYYRKKAVFLDGALPGEVVRAKVSAVHDKHIVAAVTAY
                     EKESPDRRQPPCPVYDRCGGCQLQHLAYESQLRAKEELVREAFRRYAGIEGQALPLKPM
                     LGMDDPWHYRNKAQLQLGAGRDGRIVAGLYEAQSHQLVDITGCTIQHDCINQTVEEVKA
                     ILERLHIAPYDVKRRSGVVRTIIVRTGFQSDDLQLTLVTGTETLPKSDQLVSELLRKVP
                     GLTTIAHNINTRKTSLVFGDKTRILWGKPTMEDSLGDLKFSLSPRAFFQLNPQQTLKLY
                     EAVRVAAALSGRERVVDAYCGTGTIALWLAPYAAEVRGIEIIPEAVDNARQNADRSGRT
                     NAAFYAGEAEALLPRWVKDGYRPDVIVVDPPRTGCDERLLRAILAAKPKRLVYVSCNPS
                     TLAKDCKALLAGGYELASVQPVDMFPQTAHVEVTVRLERIDTAK"
     gene            complement(4723..5247)
                     /db_xref="GeneID:76996441"
                     /locus_tag="FLT43_RS10725"
                     /old_locus_tag="FLT43_10725"
     CDS             complement(4723..5247)
                     /codon_start=1
                     /db_xref="GeneID:76996441"
                     /inference="COORDINATES: protein motif:HMM:NF024800.4"
                     /locus_tag="FLT43_RS10725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10725"
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
                     /protein_id="WP_087444901.1"
                     /transl_table=11
                     /translation="MQRSLMQVPNTYQELIRLYANLHEWNGNRVIGVDPLLEMLQDYRE
                     ETTGTLAKAELYKERRKIESDKHIVIENAHPPIISEDDYKTVQELMQRKGKHKSNGKES
                     LFSYIVKCPDCGSGMHFKPDRRNGAYVCGGYVKFTSSYCSSHIIEEQALLQTVKNDLGA
                     LIQDRVKIEDL"
     misc_feature    complement(5244..5257)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            complement(5718..6437)
                     /db_xref="GeneID:76996442"
                     /locus_tag="FLT43_RS10730"
                     /old_locus_tag="FLT43_10730"
     CDS             complement(5718..6437)
                     /codon_start=1
                     /db_xref="GeneID:76996442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637689.1"
                     /locus_tag="FLT43_RS10730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10730"
                     /product="ABC transporter permease"
                     /protein_id="WP_087444900.1"
                     /transl_table=11
                     /translation="MHAALRSEKTKFFSYGWCVLGAVGAIIIPLLYLLTSDTPKTGREQ
                     EVLSLCLQALYLGQHGVIVASAGYFGQEYSHSALRTTLLTQPSRLKLLCAKFVNMSIII
                     LVTGIVSSVIGLIVLMFQHDIEWTGSFMIRLLGSISLGILSWIQLAWITSALSIMTKSF
                     IAPVAIMLPLVLGLSHMLFSFSQLAKFLPTLATMNLFSLPAVNVYLDKWPGLAVQFSWV
                     VLLLTISAWLFSYRSVR"
     gene            complement(6437..7222)
                     /db_xref="GeneID:76996443"
                     /locus_tag="FLT43_RS10735"
                     /old_locus_tag="FLT43_10735"
     CDS             complement(6437..7222)
                     /codon_start=1
                     /db_xref="GeneID:76996443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637690.1"
                     /locus_tag="FLT43_RS10735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10735"
                     /product="ABC transporter permease"
                     /protein_id="WP_087444899.1"
                     /transl_table=11
                     /translation="MKTFSRTIRIEQIKIGSSRVWWVICALVIVIQPLMALIAAKSFVK
                     IGLDATPETHPELAQALPPLDYLGFSSLTGNLPMVIFGGMIGASEYKNHQLRTTLLCQS
                     SRIKVFWAKVLALLICSVFISLLTIYATISITHVGLGELGLHPFYLSTIAWQFIGFSAL
                     NWILLTILSFGIGMLFKNALVPLAFLVPQLYNLGGYLAQRWEWAEYLPVAAGNFLIARP
                     TDPFEHDPLQGGIVLLVWVILTLIISYYAFTRNDVGGKY"
     gene            complement(7224..7940)
                     /db_xref="GeneID:76996444"
                     /locus_tag="FLT43_RS10740"
                     /old_locus_tag="FLT43_10740"
     CDS             complement(7224..7940)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996444"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637691.1"
                     /locus_tag="FLT43_RS10740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10740"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_087444898.1"
                     /transl_table=11
                     /translation="MTNTTNNIVISQLCKRHGEKNILKDVSFEAKQGRITAFLGPNGAG
                     KSSTLRILLGLDRSTGTATFGGSNYVTFDTPLKVVGAAFDGIGGAPSRRVKTHLKIIAQ
                     SNNISFRRVSEVLEIVGLSEKSKARLGTLSLGEGQRLGLAAALLGDPQYLVLDEPTNGL
                     DPTGIRWFRKFIRQQSDMGKTILLSSHLLSEVEAVADDVVIINHGKIIAAGELRHVMKN
                     LESLEDVFFSLTEGGA"
     gene            complement(7982..8668)
                     /db_xref="GeneID:77000121"
                     /locus_tag="FLT43_RS29685"
     CDS             complement(7982..8668)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:77000121"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FLT43_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_208620101.1"
                     /transl_table=11
                     /translation="MILKEVTLSAEYGKRTAIVGPSGAGKSTILQLIERFYDPISGQIY
                     VDGKDYRSYSREELRKLITYVEQNAPVVAGTLRDNLLLGNSNVSDQECYDVLKEVNLSY
                     LIERSPDKLDMKIGESGTTLSGGERQRLAMARSLLSKAKIVLLDELTSNLDSLNEIGLK
                     KAVDKMRESKTVIVVAHRLSTIVDSDIIYVLEHGRIVGSGNHNELLDKVPLYRKLAKEQ
                     FLVRAI"
     gene            complement(8732..9589)
                     /db_xref="GeneID:77000122"
                     /locus_tag="FLT43_RS29690"
     CDS             complement(8732..9589)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:77000122"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FLT43_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter transmembrane domain-containing
                     protein"
                     /protein_id="WP_208620100.1"
                     /transl_table=11
                     /translation="MLRKKTENNNPKPKELEQDERYEPIPRASLRQLFALTKGHNLEFI
                     LVVILGILSAILTLIQPNLVADLVKQSSSGFTVNITLVLLILVLSVSMILTTIQYYLLQ
                     KIGEGVVFEARSNLISHLIQKASFRVQQELGKLSGLVERDLQAIRTIRSTNATSIEENK
                     AKLQAEHLRKLGIRLAKIQSFMTPISNLSLQVCGLIVLGFGGYRVSMGYMTIADLIAFA
                     LLLFIMIGPVGQIFGAFSGIGESLGAFARIKELLDLALETDYDTNSTVTFSPNSSAQKG
                     MVLF"
     gene            complement(10001..10249)
                     /db_xref="GeneID:76996445"
                     /locus_tag="FLT43_RS10750"
                     /old_locus_tag="FLT43_10750"
     CDS             complement(10001..10249)
                     /codon_start=1
                     /db_xref="GeneID:76996445"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.4"
                     /locus_tag="FLT43_RS10750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10750"
                     /product="PqqD family protein"
                     /protein_id="WP_087444897.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.7e-20,
                     bitscore: 69.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-11, bitscore: 41.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIKRELKIIEQDNGAMIFDKRRGIYFQVNHVGRLLIQGLGEGK
                     TRNELVAELEKTFGLESANAENDVNEFLSMLREVGLA"
     aSDomain        complement(10004..10246)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FLT43_RS10750_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.70E-22"
                     /identifier="RREFam002.1"
                     /label="FLT43_RS10750"
                     /locus_tag="FLT43_RS10750"
                     /protein_end="82"
                     /protein_start="1"
                     /score="69.1"
                     /tool="antismash"
                     /translation="KKIKRELKIIEQDNGAMIFDKRRGIYFQVNHVGRLLIQGLGEGKT
                     RNELVAELEKTFGLESANAENDVNEFLSMLREVGLA"
     misc_feature    10241..10255
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.54"
                     /tool="antismash"
     gene            complement(10284..11852)
                     /db_xref="GeneID:76996446"
                     /locus_tag="FLT43_RS10755"
                     /old_locus_tag="FLT43_10755"
     CDS             complement(10284..11852)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996446"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="FLT43_RS10755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10755"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_087444896.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-12, bitscore:
                     46.0, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLAVIFQKILSKGIFVLVDNHEVIVGGALFDVSLSWKMLNDIL
                     IISDSASDIARYCDLNISKAAVALNLISSLPYYPFQDIPLWEGVNKIHPFCVLKYGKKQ
                     QFEEFKVWMPPELSNDVELTLHNIRERFFGLLRNHTKSYANISADLSGGVDSAAIAYVL
                     KAYYADIKLYHAKTDSKWNSDSKWAAMIANDMNVSLNLLPSIGVSGRRFETDMPYSGLT
                     LPDSPVFWADTEGYVEKIVNFNENYGDSVHFIGVGGDELFTPTPAYAWSVVRQNRMRSL
                     SFGFQYCLLTRTSFLQGVSNLMNNTSFKEALKTEIDIGFGYAKSRRKESVLDWFGKITI
                     PAWLAKDYHVPCYQIAMKTLNEISGGLDSDRSKHQALESLLFQRRLLSQLNVIYGSRLT
                     WLAPFLDSKIIESALSIPMRYHLKSGMTKPMLYQATKGIVPREVFTRGFKGDYSTFLYK
                     GYKESVKKNIHFVRDFKVVELGIVDPDILVSELSMPTALHNRIEAFERLSAVERWLHNA
                     MSYPS"
     misc_feature    complement(11820..11834)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.68"
                     /tool="antismash"
     misc_feature    11901..11919
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.61"
                     /tool="antismash"
     misc_feature    11947..11961
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.73"
                     /tool="antismash"
     misc_feature    complement(11966..11979)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.16"
                     /tool="antismash"
     misc_feature    12130..12143
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.21"
                     /tool="antismash"
     gene            complement(12218..12346)
                     /db_xref="GeneID:80426733"
                     /locus_tag="FLT43_RS30500"
                     /old_locus_tag="FLT43_10760"
     CDS             complement(12218..12346)
                     /codon_start=1
                     /db_xref="GeneID:80426733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370910.1"
                     /locus_tag="FLT43_RS30500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10760"
                     /product="putative RiPP precursor"
                     /protein_id="WP_115057833.1"
                     /transl_table=11
                     /translation="MTNVVYSKPTIEKVAIFKESTKGQRFGYYRDLFGGRSQSFWL"
     gene            12657..13148
                     /db_xref="GeneID:76996447"
                     /locus_tag="FLT43_RS10765"
                     /old_locus_tag="FLT43_10765"
     CDS             12657..13148
                     /codon_start=1
                     /db_xref="GeneID:76996447"
                     /inference="COORDINATES: protein motif:HMM:NF024932.4"
                     /locus_tag="FLT43_RS10765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10765"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_244194381.1"
                     /transl_table=11
                     /translation="MDVYVKFRKRALFPCAKWCNSITRVNVPWALDKPKHYFPLLFDAL
                     IIKLAKDMPMNAVSRLLGEHETRLWRMLHHYVDNAFVAQDLSYVTKISTDETSAKRGHN
                     YIAIFMDPEQKNIIYVTQWGLRCRLDPMVEVAKMLQKHDDGVIRRFYIQAEQRFTGRCE
                     "
     gene            13084..13254
                     /db_xref="GeneID:77000197"
                     /locus_tag="FLT43_RS30105"
     CDS             13084..13254
                     /codon_start=1
                     /db_xref="GeneID:77000197"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /locus_tag="FLT43_RS30105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_244951382.1"
                     /transl_table=11
                     /translation="MTVSFDGFTSKLNNGLLEGVNSLFQAATRKARGYHSEKNIIAMVY
                     VLAGKLNFALK"
     gene            complement(13456..13665)
                     /db_xref="GeneID:76996448"
                     /locus_tag="FLT43_RS10770"
                     /old_locus_tag="FLT43_10770"
     CDS             complement(13456..13665)
                     /codon_start=1
                     /db_xref="GeneID:76996448"
                     /inference="COORDINATES: protein motif:HMM:NF013753.4"
                     /locus_tag="FLT43_RS10770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10770"
                     /product="transposase"
                     /protein_id="WP_315974104.1"
                     /transl_table=11
                     /translation="MDWVGYSSQLPPMVSLARTIKQHEEGSLRWFHSKMTNGLLEGING
                     LVQAAKRRARGHRNVENLIAMVYT"
     misc_feature    complement(13855..13871)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.27"
                     /tool="antismash"
     misc_feature    complement(13947..13965)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 24.37"
                     /tool="antismash"
     gene            14367..15080
                     /db_xref="GeneID:76996449"
                     /locus_tag="FLT43_RS10775"
                     /old_locus_tag="FLT43_10775"
     CDS             14367..15080
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996449"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005544413.1"
                     /locus_tag="FLT43_RS10775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10775"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_087444895.1"
                     /transl_table=11
                     /translation="MVIKVAICDDVPVIAKAIEDLMLEYDSSLFEIDIFYNPFRLIELL
                     KGNTYDLFILDIEFPNLSGIEIAEIIRKNNYTCPIIFITSFREYMEEAFKVNTFDYILK
                     PVTKDKLYPALNRAIKYLDLDDSKFMFTFNKVFYSLSFSEIIYFEKNKRKVLIHTPSDI
                     YETILQTRALLSKVNDNFVQVHTSFIVNVRYVKQIGNNIIIANLSDKQTVEIPISRKFI
                     DSARKQILMKLRDLI"
     gene            15080..16369
                     /db_xref="GeneID:76996450"
                     /locus_tag="FLT43_RS10780"
                     /old_locus_tag="FLT43_10780"
     CDS             15080..16369
                     /codon_start=1
                     /db_xref="GeneID:76996450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019637693.1"
                     /locus_tag="FLT43_RS10780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10780"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_087444894.1"
                     /transl_table=11
                     /translation="MNDTIVALFNFVVNLVLANHYFPNNSIHKLFSKENVIITFLTFFL
                     TAFYLFSNQQSYILMNIIFTALLFLVIAKRNQIDMRKEFFWLIFLLLMFLICDSVSFFI
                     TKAVSLSEGYDSNLLFMAGGGGIAIILKLMAVAVLKIIVLQKRKLKRPINVFLLMTLLS
                     IPMISVFVLSTAEINFINPPNSIFILIATCIIYMNICILYLYITLGSYFEKLEKTTTQK
                     IVFESELNFFKQLKHSQSKLYSMKHDLKNQYVVLMGMLSQGDTAGAEKYLQNSIQKIEH
                     IDYFFTNNYVLNYLLNEKKSIAESNGITLNVKSFLPEKINLDTDIFAVVLGNLIDNSLN
                     AVLRLSNSKEKEISLLIKQFDNNLLIEISNLFDTVELKIRKNRRFEGIGIKNVKRIVEE
                     NGGIYNQWVQDNQYIVSILLLNVYDKEDEE"
     gene            16580..16648
                     /db_xref="GeneID:77000198"
                     /locus_tag="FLT43_RS30110"
                     /old_locus_tag="FLT43_10785"
     CDS             16580..16648
                     /codon_start=1
                     /db_xref="GeneID:77000198"
                     /inference="COORDINATES: protein motif:HMM:NF017355.4"
                     /locus_tag="FLT43_RS30110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10785"
                     /product="hypothetical protein"
                     /protein_id="WP_244194423.1"
                     /transl_table=11
                     /translation="MAEQAEREGGSLNQYVLYKLSR"
     misc_feature    complement(16629..16643)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.92"
                     /tool="antismash"
     gene            16787..17125
                     /db_xref="GeneID:76996451"
                     /locus_tag="FLT43_RS10790"
                     /old_locus_tag="FLT43_10790"
     CDS             16787..17125
                     /codon_start=1
                     /db_xref="GeneID:76996451"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FLT43_RS10790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FLT43_10790"
                     /product="hypothetical protein"
                     /protein_id="WP_115057831.1"
                     /transl_table=11
                     /translation="MKKGLIVLSAAATLLAGVLVPTTGFAAERSSTQPETKNVKANAGY
                     DYVPSFISVGGFFYFPSRYKHPNVWFDNGVVSIDVFGRVTGLKKGSATIRVWDEEEKET
                     KTFWISVY"
     gene            complement(<17332..>17529)
                     /db_xref="GeneID:77000199"
                     /locus_tag="FLT43_RS30115"
                     /pseudo=""
     CDS             complement(<17332..17529)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:77000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017152340.1"
                     /locus_tag="FLT43_RS30115"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVNLFLKIDEGQTLGGLAGEICWNWMEIHYLVIDEQVRKLGYGKK
                     LLLEAEKLAKEKECDIIKLDT"
     misc_feature    17507..17520
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    complement(17817..17826)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            17916..18425
                     /db_xref="GeneID:76996452"
                     /locus_tag="FLT43_RS10805"
                     /old_locus_tag="FLT43_10805"
     CDS             17916..18425
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:76996452"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017434850.1"
                     /locus_tag="FLT43_RS10805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10805"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_087444892.1"
                     /transl_table=11
                     /translation="MTIMETPRLYLRPFDDEDAASLHPIFSDPETMAYYPAPFSYKQTQ
                     AWIMRNQDRYANDGYGLWAVCLKDSGQVIGDCGLINQNVDGKTEVEIGYHINKNYWCKG
                     YASEAAAACKEYGFHRLRLSRLISIIAPQNAASIRVAEKIGFSKEKEAYIFGKNHYIFS
                     GTRATD"
     gene            18554..19144
                     /db_xref="GeneID:76996453"
                     /locus_tag="FLT43_RS10810"
                     /old_locus_tag="FLT43_10810"
     CDS             18554..19144
                     /codon_start=1
                     /db_xref="GeneID:76996453"
                     /inference="COORDINATES: protein motif:HMM:NF023011.4"
                     /locus_tag="FLT43_RS10810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10810"
                     /product="DUF3238 domain-containing protein"
                     /protein_id="WP_164776623.1"
                     /transl_table=11
                     /translation="MAHIVEIRFAAFIPEAWIEHKRTASALIQFNGNNRSFTYFTEDQP
                     ELSKMAQHIVVDFEKTKIKHFRSTGPTIERTVELSSGNVLREVFGHASDSGLTISNESI
                     SSTSASFFIQGSAANPLNADASPLDWEYDVTVDTTGKVTVKGRHDGFPAHEIYKRVDKG
                     EPVTIYTHDPRVTGDTPLSLLPPMERIVDRIAP"
     misc_feature    complement(19159..19168)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.78"
                     /tool="antismash"
     gene            19307..19831
                     /db_xref="GeneID:76996454"
                     /locus_tag="FLT43_RS10815"
                     /old_locus_tag="FLT43_10815"
     CDS             19307..19831
                     /codon_start=1
                     /db_xref="GeneID:76996454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015892934.1"
                     /locus_tag="FLT43_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FLT43_10815"
                     /product="DinB family protein"
                     /protein_id="WP_087444890.1"
                     /transl_table=11
                     /translation="MNFKMTEAIEVLERTPQTLECFLSGLSEGWLQGNEGEGTWNASEV
                     IEHLIEGEKQNWMPRLEFILQEGKDKPFPPFDRYSHLHDKHDRSMEHKLLEFKTIRTQN
                     IARLKELMETEAQLELSGFHPAFGVVKIRELIATWAVHDLTHMAQIVRVMAKRYTTDVG
                     PWIEYLGILKK"
ORIGIN
        1 tgatcgtata ctccgccagc tcgacgtcga actcgtcgcc gcagtgtgcc ttcaggcagc
       61 ggatggcaag cgaagtatga atatatttcg cgttcaatgt ggatagtacg actttcatgt
      121 tgactccctt ctatcgtcac gcaagggcgc cagacagcat tctgtccggc tcgccttgcg
      181 ccatggccta tgcaatcggc gttccgttcg gcaccgcctc gtctgtccgc agcagcacga
      241 catccccttc ttccggcacg ccgccgagca cgagcacctc cgaggagaag cccgcaatct
      301 tccgcggcgg gaaattgacc accgcggcaa cctgacgtcc gatcagcgtt tccggcgtat
      361 agcggaccgt aatctgcgcg ctcgagcgct tcaggccgag cggaccgaaa tcgatcagca
      421 gctggatcgc gggcttgcgc gccttctcta acggggccgc ctccacgatc gtgccgatcc
      481 ggatgtccag cttcatgaaa tcttcgatgg tcgcctgggc aacttgcggc tgcgcttctt
      541 ccgccgcatt cacgctgccc gtatcggcgc cattgctatg cttgttgtta gcatccatca
      601 tgcccattcc tcctgtgcgt caagccgggc cgactcttct tcccgttgac ggaagaaggc
      661 catgaacggc tcgccgaatt gttttagctt cgcttccccg atgcctttga cgagcatcat
      721 ctcggcttcc gtcgtcggca tccgctccgc catctcccgc agcgtgctgt cgttgaacac
      781 gatataaggc ggcacgcccg ccttgctcgc cagctcgcgc cggatcaggc ggagctgctc
      841 gaatatcgtc tggtcgaccg cgccggcggc cttcggcttc agcgaggtcg cgacccgctg
      901 cgtcacctgg cgctgcccct tcagcacctc ggccgcgggc ggcagcaggc ggacaaccgg
      961 atactgtcct tcgcttaact gcaaatagcc ttccgcgatc agcacataaa tcaggtcggc
     1021 gatcgccttc tcggtcaaat gccgcatctc tccgtgcgtc ggcaactttt cgaagccgta
     1081 ttggaccacc tttttgttgc gcgatccctt cagcacagag gctaccatcg agacgccgaa
     1141 ccgttcccgc atccggaaga tgcaggagaa aattttctgc gcttccgtcg taatgtcgat
     1201 cgattcgcgc tcatccttgc agttcccgca catgccgcag gtctcgtccg acatttcgcc
     1261 gaagtagcgc agcatgtacg tctgcaggca gccagtcgtg tagcagtaat cgatcatcgc
     1321 ctgcagcttc ttatattcat gtgtcttccg ctctggcgcg gcttcactct gttcaataaa
     1381 aaacttctgc gtcaaaatat cctgcggatg gaacagcagc acgcattcgc tcggctcgcc
     1441 gtcccggccc gcgcgcccgg cctcctgcac atacgcctcc atatgcttcg gcatattgta
     1501 gtgcagcaca tagcgcacgt tcgatttgtc gatgcccatg ccgaaggcgt tcgtcgccac
     1561 gatgacgcgc aagtcgtcat acaggaacgc ctcctgcata tgcgcgcgct cctcgtccga
     1621 catgccggca tgataccggc cggcggcaag acccgccttc cgcagcatct cgcacagatc
     1681 ctcgacttcc ttccgcgtcg aggcatagat gatgccgggc tgatgcgtgc gctcccgcac
     1741 ataattgagt gtaaatgccc ggcgctcctc gccgcgcagc acggcgaacg ccaggttgtc
     1801 ccgcttgaag ccggtgacca ccagctccgg ctccccaagc tcgagcagcc ggattaagtc
     1861 ctccgtcacc tccggcgtcg cggtagccgt aaaggccgcc atgagcgggc gcggacgtcc
     1921 cgcctcctcc agctccttca ggaaaggcgc gatcgcgcgg tagctcgggc ggaaatcatg
     1981 cccccactgc gacacgcagt gggcctcgtc caccgcaatg aacgcgatcg gcagcgactt
     2041 cgcccgctca cggaaccatt cgctctccag ccgctccggc gcgacataga gcagcttcag
     2101 ccgcccttcc tccgcccggc gcacaattcg tcccgcctcc cccatctcct gggtgctgtt
     2161 gatgaacgcc gcctccacgc ccaagctgtg cagcgcatcg acctgatcct tcatcagcga
     2221 gatgagcggc gagacgacca gcgtcacgcc ctgcagcatc agcgccggaa tctggtaaca
     2281 gatcgacttc ccgccgccgg tcggcataat gcctaccgta tttttacctt ccaatatata
     2341 ttcaattatt cgcttctgtc cctcgcggaa gtcatcgtag ccgaacaccc gcttcaatgt
     2401 gctccgtgct tggtccattg atatcatatc ctcgaactcc ttctcgctct ccctgctatt
     2461 gttctagtat aacctaacgc gaagccggtt gggagggcca ggccggattc tctcggggca
     2521 aggttgaatt cgtgccccgc tctttggtct tgatattggc tgctgcatta aggccgcatt
     2581 caacaaacac gaagcctagg gcattcatat ccccggtcca taagcatcaa tcattgggca
     2641 ttagaatcac gccatatgca acatcgaccc tatcggcccg tcctagcttg cctgcgtgct
     2701 tcgtcctcgc tgttcagacc ccgttgctgg cggttggcgc ccacccgttc tttttgctat
     2761 agtgagagca gttgaatctg aaggcaggag cgaagaccag acatgaacga acgaagaacc
     2821 ggtacggacc ggagtcatag aggaagcaat cctaaggagc gggcaggttg gaaaaaggga
     2881 ccccgtcccg gcgcgtccgg agcgcggccg cgggtgaccg atgcctctgc ggagcaggtg
     2941 aagagtggtg atcgcatcgt cgtcacgatc aagcggatcg gcattaacgg agaaggcgtc
     3001 ggctattatc ggaaaaaagc cgtcttcctc gacggcgctc ttccgggcga ggtcgtgcgg
     3061 gcgaaggtaa gcgccgtgca cgataagcat atcgtcgccg ctgtgacggc gtacgagaag
     3121 gaatcgccgg accggcgcca gccgccttgt ccggtgtatg atcgctgcgg cggctgccag
     3181 ctgcagcatc tcgcttacga gagccagctc cgggcgaagg aggagctagt gcgggaggcg
     3241 ttccgccgct atgccggcat cgaagggcag gcactgccgc tcaagccgat gctaggcatg
     3301 gacgatccgt ggcattaccg gaacaaagcc caactgcagc tcggcgccgg acgggacggc
     3361 cgcatcgtcg ccggactata tgaggcccag tcccatcagc tcgtcgatat tacgggctgc
     3421 acgatccagc atgactgcat caatcagacg gtcgaggagg tcaaggcgat tctggagcgg
     3481 ctgcacattg cgccgtatga cgtgaagcgc cgcagcggcg tcgtccgcac gatcatcgtg
     3541 cggacgggct tccagtccga cgacctgcaa ttgacgctcg tcacgggcac agagacgctg
     3601 ccgaagagcg accagctcgt cagcgagctg ctgcgcaagg tccccggtct gaccacaatc
     3661 gcgcacaata tcaacacacg caagacatcg ctcgtgttcg gcgacaagac gcgcattctc
     3721 tggggcaagc cgacgatgga ggactcgctc ggcgacttga aattctcgct gtcgccgcgc
     3781 gccttcttcc agctcaaccc gcagcagacg ctgaagctgt acgaggcggt gcgcgtggcc
     3841 gcggccttga gcgggcggga acgggtcgtc gacgcctact gcgggacggg cacgatcgcc
     3901 ctctggctgg ccccgtatgc agccgaggtg cgcgggatcg agattatccc ggaggccgtc
     3961 gacaacgccc gccagaacgc cgatcgcagc ggccgcacga acgccgcctt ctatgccgga
     4021 gaagccgaag cgctgcttcc ccgctgggtg aaggacggct accgccccga cgtcatcgtc
     4081 gtcgacccgc cgcgcaccgg ctgcgacgag cgtctgctgc gggccatcct cgccgccaag
     4141 ccgaagcggc tcgtctacgt ttcctgcaat ccgtccacct tggcgaagga ttgcaaagca
     4201 ctgctggccg gcggctacga actggcctcc gtccagccgg tggacatgtt cccgcagacg
     4261 gcgcatgtgg aggtgacagt gagacttgaa agaatagata cagccaagta aactgtacct
     4321 aatttgaggg gagagggtgg gaaagtttgt agtgaatttt aatctttccg ccctcgaata
     4381 cttcaatttt gtggattagc ctttggagga tttgcttcaa cacctgttca ccttcaatgt
     4441 ctaggttaac gaaggtccta cttcttttct aaaggcttgt agctgttcgt tgaggtattt
     4501 ctttgcttct acaattcagc tttcttgttc gctaggtctt actgttgttg agtgatacgc
     4561 tcattctgtt gcttgaattg ctccgttgag atagccctct caacgtgaag ccttaacaac
     4621 cagtcaaagc gtttgtcaag ttgggctaac tctctatcaa ctcgttttag ttctttttat
     4681 ggtagaggac tgtaaagcgt tcgctttttc ctccgctatt ccctaaagat cctctatctt
     4741 taccctgtcc tgtatcaatg ctcctaggtc attcttgacg gtctgcaaca gggcttgctc
     4801 ctcaatgata tgggaggaac agtaggagga tgtaaacttc acataaccgc cacacacata
     4861 cgccccatta cgtctatctg gcttgaagtg cataccgctt ccgcaatcgg ggcatttcac
     4921 gatataagaa aacaggcttt ctttgccgtt gctcttatgc ttccctttcc tttgcatgag
     4981 ttcctgtaca gttttatagt catcctctga gatgatagga gggtgggcgt tctcaatgac
     5041 aatatgctta tcactttcaa tctttcgtct ttccttgtaa agttcagctt ttgctagtgt
     5101 tcctgtagtc tcttcccgat agtcttgtaa catttctagt aacggatcaa cgccaattac
     5161 tcgattacca ttccattcgt gcaaatttgc atatagtcga attaattctt gatacgtgtt
     5221 gggtacctgc attaatgacc tttgcaaata ggctgcctca tcaagtagcc tctgttttag
     5281 ttacttcccg ataaaagcaa tagttaaata ataaggatat aggaagtaac actagtagca
     5341 cggttttaag gattttactg tgtcttaaca tgcatttcac cctttaccga aaaaacaggt
     5401 attggcggcc ttaggccgcc aattataaat ataaaactat tttttcactt gatattggaa
     5461 tgtaatttcc ttgcttttaa aatatgtatt ctgattggct ttattccgtt gtacaccaac
     5521 tttggcgtcg ggatctgaaa atgttttttc gcaattgcaa gtttctttat cttcacagct
     5581 acagcgtttc tttatttcgc taaaggtgca tttttatttt agaagaaaaa taggagcttt
     5641 ttgaacacac tctgctagat aaaaaattat gctaataaaa taagttttac attagcataa
     5701 gccactcgct tactatatta acgaacacta cgatatgaaa acaaccaagc agaaatagtt
     5761 aataataata ctacccaaga aaattgaacc gctagtccgg gccatttatc taaatagaca
     5821 tttaccgcag gtagagaaaa aagattcatt gtagccagag taggtaaaaa cttagctaac
     5881 tgagaaaatg aaaacaacat gtggctaagt cccaaaacaa gcgggagcat gatagcgaca
     5941 ggtgctataa acgattttgt cataatagat aaggcagagg taatccaagc taattgaatc
     6001 caactaagta tcccaagaga aatacttcca agtaaccgga tcatgaaaga accagtccat
     6061 tcgatatcat gttgaaacat aagaacgatt aaaccaatta cacttgatac tattcccgta
     6121 actaatataa ttatggacat gttaacaaat ttcgcacata aaagttttaa tctagatggt
     6181 tgtgtgagaa gtgttgttct tagagcagag tgcgaatatt cttgaccaaa ataacctgca
     6241 ctggcaacaa taactccatg ttggcctaaa tagagagctt gcaagcaaag agaaagaact
     6301 tcctgctctc tccctgtctt tggtgtatct gatgttaata agtagagtaa gggaatgata
     6361 atagctccaa ctgcacctag aacacaccaa ccataagaaa aaaatttagt tttctcacta
     6421 cggagcgcag catgcatcaa tatttccctc ctacatcatt acgagtaaaa gcataatatg
     6481 agatgattaa tgttaatatc acccatacca gaagtacgat gccaccttgt aatggatcat
     6541 gttcaaaagg gtctgttggt cttgcaatga gaaaattacc tgctgccaca gggagatact
     6601 ccgcccattc ccacctttgt gctaaataac ctccaagatt gtatagctga ggaactaaaa
     6661 aagctaaagg gacgagggca tttttgaaga gcatccctat cccgaaagaa agtatggtta
     6721 gtaaaatcca atttagcgct gaaaatccaa taaactgcca tgctattgta cttaaataaa
     6781 atggatgtaa gcctagttca cccaagccaa catgtgtgat agaaatcgta gcataaattg
     6841 ttaatagtga tatgaataca ctacatatta aaagtgcgag tactttcgcc caaaacacct
     6901 taattcgact actttgacat agtaaagttg tacgtaattg atgattttta tattcacttg
     6961 cccctatcat tcctccaaag ataaccattg gtaaattccc agtcagagag gaaaaaccca
     7021 aataatccaa tgggggtaat gcttgcgcta attccgggtg agtttctggt gtcgcgtcta
     7081 aaccaatctt aacaaagctt tttgctgcga taagtgccat taatggttga ataacgataa
     7141 ctaaagcaca aattacccac cacactctac ttgaaccaat ctttatctgt tcaattctta
     7201 tggttctaga aaaagtcttc atcttatgct ccaccttctg taagagaaaa gaacacatcc
     7261 tccaatgatt ctaggttctt cataacatgc cgaagttcac cagctgctat tatttttcca
     7321 tgattaataa taactacatc gtccgccaca gcttccactt cagaaagaag atgtgatgac
     7381 aacaaaatag tctttcccat gtctgattgc tgacgaataa attttctaaa ccagcgaatt
     7441 cctgttggat caagtccatt agttggttca tcaagaacaa gatattgagg gtctcccaaa
     7501 agagccgctg caagtccaag acgttgtcct tcacccaatg ataaagttcc cagcctcgct
     7561 ttgctttttt ctgataaacc gactatttcc aatacctcgg acacacgccg gaaagagatg
     7621 ttgttgcttt gtgctatgat cttcagatgg gtttttaccc ttctagaagg agcacctcct
     7681 ataccatcaa atgctgctcc taccactttc aatggagtat caaatgttac atagttactt
     7741 ccgccaaaag ttgccgttcc tgttgaacga tcaagtccta acaaaatacg aagtgttgag
     7801 ctttttcctg caccatttgg tccaagaaaa gctgtgattc tcccttgttt tgcttcaaat
     7861 gacacatctt ttaatatatt tttttctcca tgtcgcttac ataattgtga tataacaata
     7921 ttgtttgtag tattcgtcaa tataaatatc tcctccgaaa taaattagtc ttgatattta
     7981 tttaaatggc cctgacaaga aattgttctt tagctaattt tctatataat ggtactttat
     8041 ccagtaactc attgtgatta cctgaaccaa caattcttcc atgttcaaga acatagatta
     8101 tatctgaatc aactattgtc gagagacgat gtgctacaac aatgacagtt ttagactctc
     8161 tcatcttgtc aacagctttt ttcaatccaa tttcatttaa actatctaaa ttggatgtca
     8221 attcatcaag aagaacaatc tttgcctttg ataaaagaga acgagccata gctaaacgct
     8281 ggcgttctcc accagataaa gtagtacccg attctccaat tttcatgtcg agtttgtcag
     8341 gagaacgttc tatcaaatag ctaaggttta cctcttttaa aacatcgtaa cattcttgat
     8401 cagatacatt agaatttcct aaaaggagat tatctcgtaa agtccctgct acaacagggg
     8461 cattttgttc aacataagta ataagtttac gaagttcttc acgagaatag cttcgataat
     8521 cctttccgtc tacataaatt tgcccgctga taggatcata aaatctttct attaattgta
     8581 aaatagtact ttttcctgca ccagaaggcc cgacaatagc tgtgcgcttc ccatattctg
     8641 cacttaaagt aacttcttta agtatcattt ccccttcttt ttgagcaata tctgctccaa
     8701 actctaattt gttatatcca aaactaactt tttaaaaaag taccatccct ttttgtgcag
     8761 aagaattggg tgaaaatgtt actgtagaat ttgtatcata atcagtttct aaagcaagat
     8821 ctaataattc tttaattctt gcaaaagctc caagtgattc gcctattcca gaaaaagcac
     8881 caaaaatttg ccccactggt ccaatcatta taaatagtag taaagcaaaa gcaattaaat
     8941 ctgcaatcgt catatatccc atagaaacac gatacccgcc aaaaccaagg acaatcagac
     9001 cacatacttg taaactcaaa tttgaaattg gcgtcataaa tgactgtatt tttgctaaac
     9061 gtattcctaa ctttcgtaaa tgctctgcct gtagcttagc tttattctcc tctattgaag
     9121 tagcatttgt agaacgaata gttctaatcg cctgtaaatc acgttcaaca agtccactaa
     9181 gttttccgag ttcttgttgg accctaaaac ttgccttttg tatcaaatgg ctaatcagat
     9241 tgcttcgtgc ttcaaaaaca acaccttcgc ctattttctg taacaaataa tattgtatag
     9301 tagttaaaat catagaaact gataaaacca aaataagaag cactaaagta atattgactg
     9361 taaatcctga gcttgattgc tttactaaat ctgccactaa gtttggttga ataagtgtta
     9421 aaatcgcact taaaatacca agtattacta ccaagatgaa ttctaaatta tgtcccttag
     9481 ttaaagcgaa caattgtcgt aaactagctc ttggaatcgg ttcatatcgc tcatcttgtt
     9541 caagttcttt aggtttggga ttattatttt ccgttttttt cctcaacata attagataca
     9601 cttataactt tagaatataa acttacttca tccggctctc caactggagt actgtttaat
     9661 tcaacccatg catgtgccct aaaaggttct agggcgtatc cagtacacca actaacagat
     9721 cttcgtatta accacgttgc tactacaact gcaagtgaac gtctcagaca accctcttga
     9781 cttcgacatc tcttacttac tgtacatact gcatcacgaa taacctgaac ttgttccttt
     9841 gaagccgatg gatatcttct cgttaaacga gataatatct tttctaccat acttggagag
     9901 agccaattca gaggtgctga tagaagtata gctagtctag caagccatct tgctccattt
     9961 gatacttgtt ctggctgctc tggaaaaagt ggtatgtcca ttatgctagt cccacctctc
    10021 taagcatgga aagaaattca ttaacatcat tctctgcatt agcactctct aaaccaaaag
    10081 tcttttctaa ttcagccact aattcattcc tagtttttcc ttcacctaat ccttgaatta
    10141 aaagtcttcc aacgtgattt acttgaaaat aaattcctct tcttttgtca aaaatcattg
    10201 ccccattatc ttgttcaatt attttaagtt ctctttttat ctttttcata aaattgcccc
    10261 ctttctaatt aatattgtca catttatgac ggataactca ttgcattatg aagccatcgc
    10321 tcaacagcag atagtctttc aaaggcttca attcgattat gtaaagcagt tggcatagat
    10381 aattcagaga ctagtatgtc ggggtcaaca attcctagct caacaacttt gaaatctcta
    10441 acgaaatgaa tatttttttt tacagattcc ttatatcctt tgtataaaaa tgttgaataa
    10501 tctcctttaa agcctcgagt aaatacttca cggggaacaa ttccttttgt agcttgatac
    10561 aacatgggtt tcgtcatccc agattttaag tgataccgca ttggtataga taatgcagat
    10621 tcaataatct ttgaatctaa aaatggagct agccaagtta atctacttcc ataaataaca
    10681 ttaagttggc ttagtaaacg cctttgaaaa agcaatgact ctagtgcttg atgtttagaa
    10741 cggtcagaat caagacctcc agaaatttca tttagagttt tcatagcaat ctgataacat
    10801 ggaacatgat aatcttttgc aagccatgct ggaatcgtaa tttttccgaa ccaatccaaa
    10861 acagactctt tcctccgtga tttagcatag ccaaatccaa tatctatttc cgtttttagt
    10921 gcttctttaa atgatgtatt gttcataaga ttagatacac cttgtaggaa tgatgttctc
    10981 gtaagtaaac aatattggaa gccaaacgat aaactacgca ttctgttctg ccttacaacg
    11041 gaccacgcat atgctggcgt aggtgtaaac aattcatcac caccaacacc tatgaaatga
    11101 actgaatctc cataattctc attgaaatta actatttttt caacatagcc ctctgtatct
    11161 gcccaaaata ctggggaatc cggaagagtt aatcctgagt atggcatgtc tgtttcaaat
    11221 ctacgaccag acacaccgat tgatggcaat aaatttagcg atacattcat atcatttgca
    11281 atcatagcgg cccacttcga atcactgttc catttactat ctgtttttgc atgatatagc
    11341 ttaatgtctg cataatatgc ttttaaaaca tatgcaattg cggctgaatc aacacctcca
    11401 gagaggtcag cagatatatt agcatagctc ttagtatgat tccttagtaa tccaaaaaac
    11461 cgctctctta tattgtgcag cgtcaattct acatcattac ttagttctgg cggcatccaa
    11521 actttgaatt cttcaaattg ttgttttttc ccatatttca aaacgcaaaa tgggtggatt
    11581 ttattcacac cttcccataa aggtatgtct tgaaaaggat aatatggtag actacttatc
    11641 aagttcaatg caactgctgc ttttgatata tttaaatcac aatatcgcgc aatatcacta
    11701 gccgaatcac taataattaa aatatcattt aacattttcc atgataaaga aacatcaaat
    11761 aatgctcctc ctacaataac ttcgtgatta tcaactagaa caaagatccc tttagaaaga
    11821 atcttttgaa aaattaccgc taattttgac atctcaaatt ccttagttcc ctgtatctgg
    11881 tctgcaactt ttggatattc acatcgtata cagtatatct ctaggtcgcc tttagaatgc
    11941 ttaacatact catgttgaga aataagcaaa atgcttgccg aaactgtttt tatatgtact
    12001 tgaaatggta ctttatcaga acttgatttt gttaactttt cttttaactg agtgcgaata
    12061 atagtctccc ctctcgctta attttaaata ttttcaacaa aatttacata cgagtctcta
    12121 aaacaatcga tttttcacaa aaagtggtca ctggacatct caaaattatc caatgaccac
    12181 ttttctctca gttgtttaca atccataata ttgagctcta caaccaaaaa gattgagatc
    12241 taccaccaaa aagatctctg tagtaaccaa acctttgccc tttagtagac tctttaaaaa
    12301 tagcaacttt ctcaattgtt ggtttagagt aaacaacgtt tgtcattgaa ttccacctcc
    12361 tttactatat gctcacacca cacacattag attcaaaata gaaattaata ttctatttgt
    12421 tttaataata atctattttt aactcttttt ttctttcatg taacaaactg caacttaaat
    12481 gtaatcattg gcttattcgc cgttaaaaat acaaatacct attaagactg gaaatcaaga
    12541 gacaagtaga agatgaggtt tcatatgttt gtcaatctaa aggaagggca actagaggag
    12601 cttcttcata ccgtggtaca ttcgtgaggt ggagttcagc ctggaagcca aagcaattgg
    12661 acgtatacgt caagtttcga aagcgggcgt tattcccatg tgcaaagtgg tgcaattcca
    12721 tcacccgagt caatgttccg tgggcactgg ataaaccgaa gcattacttt cccctgctct
    12781 tcgatgcgct catcatcaag ctggccaagg atatgccgat gaatgccgtc agtcgattgc
    12841 tcggagaaca tgaaactcgg ctgtggcgta tgcttcatca ttacgtggac aatgcgttcg
    12901 tggcgcagga cttgtcctac gtcactaaaa taagtacgga tgaaacgtcg gctaagcgcg
    12961 gtcacaacta catagccatc ttcatggatc ctgagcaaaa aaacattatt tacgtaactc
    13021 agtgggggct gcgctgccgt ttagatccga tggttgaagt cgcaaaaatg ctgcagaagc
    13081 atgatgacgg tgtcattcga cggttttaca tccaagctga acaacggttt actggaaggt
    13141 gtgaatagtc tcttccaagc cgccacacga aaggcaagag gttaccactc tgagaaaaac
    13201 atcatcgcca tggtctatgt actggcaggg aagctcaatt tcgccttgaa atgaaaaaag
    13261 aattggcaac agcatggagc cacgcatcgc tagcggcgaa gattccatta ttgacatcat
    13321 tttctattct agtataataa ttggatatag agaacaggat ctttggctct tcgctctact
    13381 gggtgggtac agttttgaat attagtttaa gagccccttc cgcctttaag agattttcag
    13441 atgtagaaat atctgtcaag tatacaccat cgcgatcaag ttctctacgt tcctgtggcc
    13501 tctggcccga cgtttagctg cttgaaccag accattaatg ccttccaaca agccgttcgt
    13561 catcttacta tggaaccatc gaaggctccc ttcttcatgc tgcttaatcg ttctagccaa
    13621 acttaccatg ggtggaagtt gggacgaata gcccacccaa tccactccta ttatcgtaat
    13681 attgagcagt attgaccatt tttctatgat tcagacttta cgccattcag tatagcgagg
    13741 aagcataatt ttttagcaac ataaatatga tttactgtca ataaagtaga caaaataaga
    13801 cggctatgca gttttgcttc tgtaatattg ggactcaaat cgatcgggtg aaagataccc
    13861 caacgagcta tggattctct ttcgattgta gaagaattca atgtaccaat ggactcgacg
    13921 agttattctt tgatgtcgct tagatctttc cgattctttc gcattcagcc acttgtaaaa
    13981 tccgctccgt gatacgctaa gaattgagca catcttctcg ctccgaaaca cagagcggtg
    14041 ttccttgata aagctaaact ttatttcgga tctttggtga agtagtgcat ggcttttttt
    14101 aggatggcat tttcctcctc aagatctttt atcctttttt ccaattcttt ttgtgcttga
    14161 tcctgaggtc gtaaattacc gctaccaaca aaagcctcat ctctaaattg ccggttatta
    14221 tctactcaat ccattcgttg tgtctactta ttagtctaat tgcaatatat actaattgta
    14281 aaataatatt ctttacacat aaattgttgt ttataccacg atcgtgcatc atagctacaa
    14341 ttcaccatta ttaaaggagt aaaacgatgg taataaaagt tgctatttgt gatgatgttc
    14401 ctgttattgc aaaagctatc gaagatttaa tgttagaata tgactcctcg ttatttgaaa
    14461 ttgatatatt ctacaatcca tttcgtttaa ttgaattact taaaggaaat acatatgatt
    14521 tgtttatttt agatattgag tttcctaatc tatcgggaat agagattgcc gagatcatta
    14581 gaaagaataa ttatacttgt ccaattatct ttattacaag tttcagagaa tatatggaag
    14641 aggcttttaa ggttaacact tttgattaca ttttaaaacc agtaacaaaa gacaaactat
    14701 atcctgcctt gaatcgcgct attaaatatt tagatttaga tgattcaaaa tttatgttta
    14761 catttaacaa agttttttac agtctttctt ttagtgaaat tatttacttt gaaaaaaata
    14821 aaaggaaagt acttattcac acaccctctg atatatatga aacgattctt caaacaagag
    14881 cccttttatc caaagttaat gataattttg tgcaggtaca cacctcgttt attgttaatg
    14941 ttagatatgt aaaacaaatt ggcaataata taattattgc caatttaagt gataagcaaa
    15001 ctgttgaaat accaataagt cgtaaattta tagatagtgc cagaaaacaa attttgatga
    15061 aattaagaga cttaatataa tgaatgatac tatcgttgca ttattcaact ttgttgttaa
    15121 tttagtgttg gctaatcatt attttccaaa taactccatc cataaactgt tttctaaaga
    15181 aaacgtaatt attacattct tgactttttt tcttaccgca ttttatctgt tttctaatca
    15241 acaatcatat attcttatga atatcatctt cactgcttta ttgtttttag ttatcgcaaa
    15301 gaggaatcag atagatatga gaaaagagtt cttttggtta attttcttac ttttaatgtt
    15361 tttaatttgt gattccgttt cgttttttat tacgaaagcg gtatcgctat cagaaggtta
    15421 tgattcaaat ttactcttta tggctggagg aggaggtatt gctataattt taaaactaat
    15481 ggctgtagct gttcttaaaa ttatcgttct ccaaaagcgt aaattaaaga gaccaataaa
    15541 tgtttttctc ctaatgacac tactttctat accaatgata tcggtatttg tattaagtac
    15601 tgctgaaatt aattttatta atcctcctaa ttctatattt atattgattg ctacttgtat
    15661 tatttatatg aatatatgca tactatatct ttatataacc ctcggaagtt attttgaaaa
    15721 gcttgaaaaa actacaacgc aaaaaatagt atttgaatca gaattgaatt tttttaaaca
    15781 actaaagcat tcacaatcca aactatattc aatgaagcat gacttaaaaa accaatacgt
    15841 agttctaatg gggatgttaa gtcagggaga tactgctgga gctgaaaaat atcttcaaaa
    15901 ttcgatacag aaaatcgaac acattgatta tttttttaca aataactatg tgctaaatta
    15961 tcttctgaat gaaaaaaaat ctattgctga aagcaatgga ataactttaa acgttaaatc
    16021 tttccttcct gaaaagatta atttagatac tgatattttt gcagttgtgc taggaaattt
    16081 aatagataat tccttaaacg cagtcttacg tttatctaat tctaaagaaa aagagatttc
    16141 acttcttatc aaacaatttg ataataacct acttatagaa atttcaaatt tatttgatac
    16201 tgtggagctt aaaattcgaa agaatagacg attcgaggga ataggaatta aaaatgtgaa
    16261 aagaattgta gaagagaatg gtggaattta taatcaatgg gttcaagata atcagtatat
    16321 cgtaagtata cttttactca atgtatatga taaagaagat gaagaataga aaagactggt
    16381 agggtcgctc ctggatcggc tacacttaat tggacagtag cagcaggaag acaacatcac
    16441 gaagcccatc attgaaatct tcgagaagaa tcgaaaagca tatggcacaa gcttcatgaa
    16501 cgtggactcc ggagccgacc gagcttgatg cgtacagcgg caaattcaag tacgttcccc
    16561 gaagattctt caccggcagc tggcggagca ggcagaacgg gaaggcggat ccttaaacca
    16621 atacgtgctt tacaaattga gtcgctgaat aagcggtttt ttcttttgca gaaacccaat
    16681 aaccttacaa taaccttaca atagctctaa atatattgtg aaatgttaaa ttatagatta
    16741 cgatgacctt gctacaaaaa ataacaaaat tgtggaggtt gttacagtga aaaaaggtct
    16801 tatcgtatta agtgcggcgg caacactgct ggcaggtgtc ttggttccaa caacaggttt
    16861 tgcagctgaa agaagtagca cacaaccaga aactaaaaat gtaaaagcca atgctggcta
    16921 tgactatgtg ccttctttta tttcggtagg cggttttttc tattttccaa gcagatataa
    16981 acaccctaat gtctggtttg ataatggtgt ggtatcaatt gatgtctttg gtagagtaac
    17041 aggtctgaaa aagggttcgg caacaattcg ggtatgggat gaagaagaaa aggagacaaa
    17101 gacgttctgg atttcagtat attaattttg ttttaggtcg ctgattattc agcggctatt
    17161 tattttatcg aggggagatg atgtacatgg cattgacgga caagcagaag gcgtttgtct
    17221 aggagtacct gatagacccc aataccacgg attcggcaga cggcgcatgt ggagagttgt
    17281 tcgctgctga tacgaattgg aggtgtagcg gcgttctcca tataacggga acgtatcgag
    17341 tttaatgata tcgcactctt tctccttagc gagcttttcg gcctctaata aaagcttctt
    17401 cccatagcct aatttacgaa cctgttcatc aataacaaga tagtgaatct ccatccagtt
    17461 ccaacatatt tcgccggcga gtcccccaag agtttgacct tcatcaattt ttaaaaacaa
    17521 atttacctct tacaacccca tacttcgaca tattcaacga tgattccatc cggatgctgt
    17581 acgcatgttt ttccggttgg aacttccttc actctcgaac gaaccttgtc cctatttcct
    17641 tacgcctgtc ccatatctcc tatggtaaaa taagtatact cttctgaata ggtgacaaca
    17701 aaagagaaca accaacgaca aggattatcg acctcactcg tgaaattatt attacataag
    17761 ttcaatgaaa aacagattat tgcctggtgg gagtgcatgg agagcaatat cgcttctcaa
    17821 aaaacagccg agaaggcagg cttatgtaaa acgcatcgtt acaaaataaa ttggttttct
    17881 ttttaattta actaaatgaa aatgagtgat aaaacatgac tatcatggaa actccaaggt
    17941 tatacctaag gccattcgat gatgaggatg ccgcctccct ccatcctatt ttttcagacc
    18001 cggagacgat ggcgtattat ccggctcctt tcagctacaa gcaaacccaa gcctggatca
    18061 tgagaaatca agaccgatat gcgaatgacg gttatggatt atgggccgtt tgtctgaagg
    18121 attcggggca ggttattggg gactgcggac ttattaatca aaatgtagac ggcaaaacgg
    18181 aggttgaaat cggctaccat attaacaaaa actattggtg caaaggctat gcttcggaag
    18241 cagccgcagc ttgcaaggaa tatggatttc accgtttaag attaagcaga ttgattagca
    18301 tcatcgctcc ccaaaacgca gcatcgatac gtgtagctga aaagatcgga ttttccaagg
    18361 aaaaagaggc ttatattttc ggcaaaaatc attatatttt ctcgggtact agggctactg
    18421 attaatcttt tttccattga tggtgatgat tcgttgtaaa gcatcacgac tttctctttt
    18481 caattcgaca tatatatcga taatgaccct atacagcatg ggtgttcatc aatcaataaa
    18541 ggaggttgtt cctatggcac acattgttga gatacgcttc gctgcattta ttcctgaagc
    18601 atggatagag cataagcgaa ccgcgagtgc gctcattcaa ttcaatggca acaacagaag
    18661 ctttacttat ttcaccgaag atcaacccga gctttcgaaa atggcacagc atattgtcgt
    18721 ggatttcgag aaaacgaaaa taaaacattt tcggtcgaca ggcccgacaa tcgaaagaac
    18781 cgttgaacta agcagcggta acgttttgcg ggaagtattc ggccatgcct ctgattcagg
    18841 actgaccatc tcgaatgaga gtatctcaag cacgtcagcg tcgtttttca tacaaggcag
    18901 tgcggcaaat cctttgaacg ccgatgcttc tccacttgac tgggagtatg acgtaacggt
    18961 tgacactaca ggaaaggtaa ccgttaaggg gcgccatgac ggctttccgg cgcatgaaat
    19021 ttataaacgt gtagataagg gcgagccggt tactatctat actcacgatc cgcgcgttac
    19081 aggcgatacg cccctgtctc tgctccctcc aatggaacgt attgtagaca gaatcgctcc
    19141 ttaaaccctc atactgtgct tcgccttctc cttcacccaa acccatttcg atgtagcaga
    19201 gatccgtgaa aattcggtaa actgcaaata tagaccaaaa gctggcatat cttattgatg
    19261 gattgagaag aggagcttgg catgaatcac gggaaggagc tggcccatga attttaagat
    19321 gacggaagcc atcgaggttc tggaacgcac accgcagaca ttggagtgtt ttttgtctgg
    19381 tttatcggag gggtggctgc aaggcaatga aggcgaagga acttggaatg cctctgaagt
    19441 gattgagcac cttattgagg gagagaagca gaattggatg ccacggcttg agtttatttt
    19501 gcaggaaggg aaagacaaac cctttccccc gttcgatcgc tattctcacc tgcatgacaa
    19561 gcatgaccga tccatggaac acaagctgct cgaatttaaa acgataagaa cgcaaaatat
    19621 agccagactg aaggagctta tggaaacgga agcgcagctt gaattgtcgg gctttcaccc
    19681 tgcgtttggt gtcgtgaaga taagggaatt gattgcgacg tgggcggttc atgatttaac
    19741 gcatatggct cagatcgttc gcgtcatggc taagagatac actaccgatg tcgggccttg
    19801 gatagagtat ttgggaatct tgaaaaagta ggcatgaggg gcggcgaacc cctctttttt
    19861 gttgttaagc cggctatcgt tcggtgccag tgactagttg gcggatgtca aaatagatag
    19921 ttgaagcatt ccaataattg ggctatcata attagtatct gatactaata gcaattacta
    19981 agtccgttta ttcgtctgca gggtatcgaa tggaggaatg attttggagg acctgtctgc
    20041 tccacaacgt cgcactgata atcatcaacc cgatcatcaa ccgccaactc catggacaga
    20101 agttgacaca caggtcaccg gggccggcga ttatgttatc gatgtaaccc cgattcgcca
    20161 tactatcgct tcgcgtacga ggctgagcag aacggaaatc cctcatgccg ggatgatgat
    20221 agaagcggat gttactaatt tagtattgc
//
