LOCUS       NZ_VFNO01000009        23554 bp    DNA     linear   CON 16-AUG-2024
DEFINITION  Brevibacillus sp. AG162 Ga0222362_109, whole genome shotgun
            sequence.
ACCESSION   NZ_VFNO01000009
VERSION     NZ_VFNO01000009.1
KEYWORDS    WGS; RefSeq.
SOURCE      Brevibacillus sp. AG162
  ORGANISM  Brevibacillus sp. AG162
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Brevibacillus.
REFERENCE   1  (bases 1 to 242699)
  AUTHORS   Venturi,V.
  TITLE     Genome sequencing of rice bacterial endophytes
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 242699)
  AUTHORS   Venturi,V., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2019) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.12.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 236.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_006715575.1-RS_2024_08_16
            Annotation Date                   :: 08/16/2024 02:19:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,054
            CDSs (total)                      :: 5,923
            Genes (coding)                    :: 5,868
            CDSs (with protein)               :: 5,868
            Genes (RNA)                       :: 131
            rRNAs                             :: 1, 6, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 6, 5 (16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 25 of 55
            Pseudo Genes (incomplete)         :: 38 of 55
            Pseudo Genes (internal stop)      :: 3 of 55
            Pseudo Genes (multiple problems)  :: 11 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:50:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 202332
            Orig. end                         :: 225886
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VFNO01000009.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23554
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23554
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23554
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13554](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13554)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    647..662
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.53"
                     /tool="antismash"
     gene            complement(959..2071)
                     /locus_tag="FB479_RS23895"
                     /old_locus_tag="FB479_109233"
     CDS             complement(959..2071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017249975.1"
                     /locus_tag="FB479_RS23895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109233"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_142066937.1"
                     /transl_table=11
                     /translation="MKNWQKGMLATAVTVGLIFSSVGQVPALANSATTSTQKKISKLVV
                     DTKTVKLKKAGTQQLNVRVQYTDKTTEDVTQQAEWTSSDSDIASVEKGLVTAVSSGKTR
                     VKASFGGKSVNVPVEIDVISKLAADQKKLALSVGGTKQVNATATFSDKSTADVTAHAEW
                     ESDDTEIVTVANGLVTAVGSGKAKLKVKYGDRSVSIPVEVDVVSKLDSDKKKLYLRPDT
                     TQSITLLATLSTKEKVDVTSKAKWTSDDEKVATVENGVVKTVGSGKTRIKATYGGKTVS
                     IPVESAVISKLEFDTKKATLKVGESKDLKVSAVYTDKTKVDVTTDADWISTNSSVVTVA
                     DGKITAVKAGGATIAATYNGKVVKIQVTVK"
     gene            complement(2158..3345)
                     /locus_tag="FB479_RS23900"
                     /old_locus_tag="FB479_109234"
     CDS             complement(2158..3345)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017249974.1"
                     /locus_tag="FB479_RS23900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109234"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_106654105.1"
                     /transl_table=11
                     /translation="MKKIMKQDQDVTKQHNKQMILDIIKKQRPISRAEIAKITRMSATS
                     IGRFVSELCEEGLIRETELTSSGVGRKAIMLDIEPGAIYTIGVDMAKKRISFGIMDFSE
                     AIIAQHRMDHKTQDSTPEETAELICNEIEGMLNQTGIPIEKVVGIGIGMPGVINYEQGI
                     VQLSTTLEWKDVAFASLIEKRLKIKTVIDNDLKVKILSEYLYGSAKGSNKTALIGIGTG
                     IGSALIINGEVFRGGSNSAGELGHTTLDPNGNLCECGKRGCLQTYIDENSLIIEARRVK
                     DVSDVRQVFAAARNEERWAKEIVSRTALYLGITINNIVCMYNPDTVIVSGDLVENYREI
                     IDLVEEHSDQVIWEPFKGKFRVIPSELKGEAIVMGAGALAMQHFAPLAGTWAEES"
     gene            complement(3481..4401)
                     /gene="metA"
                     /locus_tag="FB479_RS23905"
                     /old_locus_tag="FB479_109235"
     CDS             complement(3481..4401)
                     /EC_number="2.3.1.46"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008899 - homoserine O-succinyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019281 - L-methionine biosynthetic process
                     from homoserine via O-succinyl-L-homoserine and
                     cystathionine [Evidence IEA]"
                     /codon_start=1
                     /gene="metA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740639.1"
                     /locus_tag="FB479_RS23905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109235"
                     /product="homoserine O-succinyltransferase"
                     /protein_id="WP_142066938.1"
                     /transl_table=11
                     /translation="MPIKLPDELPATEILAQENIFVMKDSRAFTQDIRPLRIVILNLMP
                     VKETTETQLLRLLGNTPLQVEIVLLHMSSHTSKNTSEEHLSMFYKTFEEIRDQRFDGMI
                     ITGAPVEQLEFTDVTYWRELTEILDWKMENVTSTLHICWGAQAGLYHHFGVPKHPLPEK
                     MFGIFPHTLNKQNVKLFRGFDNYFHIPHSRHTENRREDIEQVSELEILSESDEAGVYIV
                     ATRDGRQIFVTGHSEYDPTTLQDEYQRDVNKGLDIAVPRNYYPKDDPSREPIVTWRAHA
                     NLMFSNWLNYYVYQETPYDLNNNKR"
     misc_feature    4514..4530
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 25.46"
                     /tool="antismash"
     gene            complement(4544..5788)
                     /locus_tag="FB479_RS23910"
                     /old_locus_tag="FB479_109236"
     CDS             complement(4544..5788)
                     /EC_number="1.4.1.-"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721951.1"
                     /locus_tag="FB479_RS23910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109236"
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="WP_142066939.1"
                     /transl_table=11
                     /translation="MLHTVEKENLNPYEIVQKQIDAAAALLGLRTDAVEILKRPKRVLA
                     VSFPVKMDDGSVRVFEGYRSQHNDAVGPTKGGIRFHPDVTMDEVKALSMWMSFKCGVVG
                     RKGGVICDPHEFSKSELERVSRGFMEAIADIVGPETDIPAPDVYTTPQIMGWMMDTYSR
                     LRGTYSPGVITGKPLSVGGSKGRNEATARGCVFTILEALKDSGRKPEQTTVAIQGFGNA
                     GRIAARLLTELGFKIVAVSDSRGGIYDAAGLDIEKVGQLKDNATILEYVGGTVISNEQL
                     LKLEVDILIPAALENVITAANAHSIQAKWIAEAANGPTTPDADAILREKGIIVIPDILA
                     NAGGVTVSYFEWVQNLMNYYWSEQEVNEKLQTTMINAYRAVKELSDQYKVDLRTGAYMI
                     SLLRITEAMEARGWI"
     gene            complement(5987..7435)
                     /locus_tag="FB479_RS23915"
                     /old_locus_tag="FB479_109237"
     CDS             complement(5987..7435)
                     /EC_number="6.3.4.21"
                     /GO_function="GO:0004516 - nicotinate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017249971.1"
                     /locus_tag="FB479_RS23915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109237"
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="WP_106654102.1"
                     /transl_table=11
                     /translation="MQSFGVALHTDKYQINMMYAHWVNGTHNQKVVFEAFFRKLPFGNG
                     YAVSAGLERIISYIKNLRFEESDLKYLSEQEENYDPKFLEELRQLRFKGSLYSVKEGTV
                     VFPNEPLIRVEGRVMEAQLVETALLNYMNYQTLIATKASRIKNVAGNDVLMEFGTRRAQ
                     EADAALWGTRAAYLAGFDATSNMLAGKMFGIPTKGTHAHAWVQSFESEAEAFERFAKAL
                     PGQVTLLVDTYDTLKSGVPNAIKLGKQMEKEGKKLAAVRLDSGDLAYLSIKTREMLDKA
                     GLPDVKIVASNDLDEHTIMNLKVQGARVDSWGVGTQLITAADQPTLGGVYKLVAREGAD
                     GKYQPTIKISGNPEKVTTPGIKDMYRLIDPETGKAIADYMCFPHETTVEEGAPLHLFHP
                     SHTYLSKHLENYQAESLLVPVFVDGELVYELPTLQEIRNYHREQLKLFWPEYLRMLNPE
                     HYRLHISEEMWETKTKLMKAYLKK"
     misc_feature    complement(7496..7513)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            7581..8231
                     /locus_tag="FB479_RS23920"
                     /old_locus_tag="FB479_109238"
     CDS             7581..8231
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030151 - molybdenum ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740636.1"
                     /locus_tag="FB479_RS23920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109238"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_142066940.1"
                     /transl_table=11
                     /translation="MNRKIVTISKGLPKSNMYNGKEYLSGIWKEEAGELVVRSEKIDED
                     DIANPEYHGGPDRVVCAYPFEHYAHWEKLFGQPLTNAAFGENLTLVGMTEEQVCIGDVY
                     QFGDTILQVTQGRYPCATINKRNNNNQLLKAVVEMGYTGYFFRVLQEGTIKPDSKITLV
                     TAHPKQVTVASIHHLYFHDKSPSQETIQRMLEVEELAQPWRKKLLEKLEKQQQ"
     gene            8247..8933
                     /gene="rluF"
                     /locus_tag="FB479_RS23925"
                     /old_locus_tag="FB479_109239"
     CDS             8247..8933
                     /EC_number="5.4.99.21"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rluF"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1154: Pseudouridine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721945.1"
                     /locus_tag="FB479_RS23925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109239"
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="WP_142066941.1"
                     /transl_table=11
                     /translation="MRINKFISETGICSRREADKLIEAKRVTINGQLAELGSTAAPGDD
                     VRIDGQPLGAKKKDVYIALNKPVGITCTTELHIKGNIIDFVNHPERIFPIGRLDKDSQG
                     LILLTNDGDIVNKILRAENNHDKEYIVTVDKPITANFLHGMANGVRILGTTTKPCKVTK
                     VSDRVFNIVLTQGLNRQIRRMCQAFGYQVRKLERVRIMNITLGNLKLGQWRNLTAKELT
                     DLNKSL"
     gene            9148..9348
                     /locus_tag="FB479_RS23930"
                     /old_locus_tag="FB479_109241"
     CDS             9148..9348
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721941.1"
                     /locus_tag="FB479_RS23930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109241"
                     /product="cold-shock protein"
                     /protein_id="WP_048031267.1"
                     /transl_table=11
                     /translation="MEQGTVKWFNAEKGFGFIEREGKEDVFVHFSAIQGEGFKSLDEGQ
                     KVTFDVEQGQRGPQATNVQKV"
     gene            complement(9548..9754)
                     /locus_tag="FB479_RS31305"
     CDS             complement(9548..9754)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012257.4"
                     /locus_tag="FB479_RS31305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="WP_370511700.1"
                     /transl_table=11
                     /translation="MDEGEFFENAPLILDGLVRIFKLSSDGREVTLYRLSAGECCPLIA
                     SSILGETVYEASACAANYAYSTF"
     gene            complement(10001..11587)
                     /locus_tag="FB479_RS23940"
                     /old_locus_tag="FB479_109243"
     CDS             complement(10001..11587)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009676357.1"
                     /locus_tag="FB479_RS23940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109243"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_142066942.1"
                     /sec_met_domain="PF00881 (E-value: 1.8e-07, bitscore: 25.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRDVFLHNLLYDIEKIIPADWTVDWEDSPLVYKIYRELPVVPLS
                     LEVPLSLEHGRNKQSSKPTIRDIGHFLWVTFGLTRVSDPGNDWDFFDQRSEELFRRFVP
                     SGGALYPSELYVYVNIDDLPEGVYHYDAAHHRLVLLRKGNCDSYLAMALGGYCDMSECF
                     AAVFVSTMFWKNFFKYHNLSYRLQGLDAGVLIGQLLEAAKRFGFTTGVYYQFLDRAVNH
                     LLGLNQWEESVYAVIPLSIKSDINWFAHKREGMAIVWDKELYQKLPAVQHHSYIRSRRI
                     RKYPMLIKLNEASKFESTDCFHRVRGEKKPVFGGPSLALPNVKPLNWDLMEASRKRFSP
                     GERFILREVSQQQLATLLREATNAFFYRNDLDRIDIPEIQEQPRSRVSLYCCLYSVEGI
                     PAGAYYYDYLSHKLRLIRLGDHRPILKQAMTMSDFDVPICLHVVGDYHYYRHKLGYRGY
                     RIQQMEAGILVQKLLLVASSIGLAGHPLLDYDAKTCDKIYKITNVNQSCLIQVPVGPYR
                     LPNTLTGHLYV"
     gene            complement(11611..13554)
                     /locus_tag="FB479_RS23945"
                     /old_locus_tag="FB479_109244"
     CDS             complement(11611..13554)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003340796.1"
                     /locus_tag="FB479_RS23945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109244"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_142066943.1"
                     /sec_met_domain="YcaO (E-value: 1.4e-80, bitscore: 265.5,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 1.1e-124, bitscore:
                     410.0, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVLMIVGEGLLADFVYRNLSSQYSVVQQPDCKADIPKEVELAL
                     VLHDFWHPSIHLQAEEVFKKAGIPWLRGFVSFGEGVVGPLVGPRMQGCPQCADFRRLMT
                     RKNRRDLREIQLQIKNQKKRQRDAWASNTGMYQLANMITAEAQRVLQGSRPYTEQRTRI
                     HLVNLQTLATSEHFFLPNPICEVCGELPEDTPEAARITLQPRPKANPNSYRICSLDVFK
                     EVLIQEYLDFRTGMINQKTKDHLTPFAVMSVNLPMITSNEGAAGRTLSYEQSELTAILE
                     ALERYAGLHPRGKRTVICDSYEKVKDHALNPLKIGLHSEEQYASPDYPFQRFDPKRPMN
                     WVWGYSFFKEKPILVPESIAYYDLKDDFVYENSNGCALGRCLEEAIFYGILEVVERDAF
                     LLTWYAQLPLPRLDPESAKDKELLLMIERIKAVAGYDLYLYNATMENGIPSVWAITKNR
                     KQKGVNLVCAAGSHPDPLRAVKTAVHELADMLLTLDEKYETHREEFLQMLHDPFRVQSM
                     EDHGMLYSLPEAEERLHFLLHDDRPMRTFDEEFKLQAGHHDLTDDLKGILQIFKQLNLE
                     VIVVNQTTPEMIRNELYSVKVLIPGMLPMTFGYHLTRVTGLDRVLNVPMQLGYTKHPLT
                     YEQLNPHPHPFP"
     gene            complement(13554..15470)
                     /locus_tag="FB479_RS23950"
                     /old_locus_tag="FB479_109245"
     CDS             complement(13554..15470)
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003252874.1"
                     /locus_tag="FB479_RS23950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109245"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_142066944.1"
                     /sec_met_domain="TIGR03693 (E-value: 4.2e-206, bitscore:
                     679.9, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     3.3e-40, bitscore: 130.0, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 8.2e-17,
                     bitscore: 55.0, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSVNPSMRLKVKGDTYYVPDPDGRVYFQNNLGSFQMEGKGIDKW
                     IEKLMPLFNGEHTLEELTTGLSDQRRNHIYHIADMLYQNGFVHDWSSQLSHQLSKEIME
                     KYAPQIEFLNSFTDSAAYRFQLYRQTKVLAVGSGPLLSALVAALLESGLPAIYIATTHS
                     METNRERLWELAAHARKEDSEVKLEEIYLQKNDRDGWQKAVQTFQVVLYVQQEGDLEEL
                     RVLYSICKEQNKIFIPAIYHDQVGIAGPVLRPDADGCFESARRRIHRSSFKNGSCFSAY
                     SPISAAMLANIVVFELLKTITGTSGQENKIFLMNLETMEGEWHPFTPHPLVTGGARVKW
                     VKDTNLLFEQRLPQNGSYDLPAFFGSLTSEQTGIFHTWDEGDLEQLPLAQCRVVVVDPL
                     SEGPVELLADIVCSALTHDGARREAGLAGIETYASRMAKPLFGTEEFIGIGAGETVPEA
                     VTRGLQKSLTAELRKQLENHQTAVYPVELSSIEDKHSLFYLQALTIMNGPPTVCLGEEI
                     SGFPVVWIGTNDRWYYSVCLHLTMGLRTVLQQALWVNHNPSLSQTTTYGINPSSIVVKE
                     KLPHSLVIPTVEEAAHSEMLQAALSSLRRNNKELFVCELELEQVFKEELAGVFGVLLRK
                     DES"
     aSDomain        complement(15174..15470)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FB479_RS23950_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.60E-41"
                     /identifier="RREFam011.1"
                     /label="FB479_RS23950"
                     /locus_tag="FB479_RS23950"
                     /protein_end="99"
                     /protein_start="0"
                     /score="130.0"
                     /tool="antismash"
                     /translation="MTSVNPSMRLKVKGDTYYVPDPDGRVYFQNNLGSFQMEGKGIDKW
                     IEKLMPLFNGEHTLEELTTGLSDQRRNHIYHIADMLYQNGFVHDWSSQLSHQLS"
     aSDomain        complement(15207..15449)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FB479_RS23950_Thiopeptide_F_RRE.1"
                     /evalue="9.00E-18"
                     /identifier="RREFam004.1"
                     /label="FB479_RS23950"
                     /locus_tag="FB479_RS23950"
                     /protein_end="88"
                     /protein_start="7"
                     /score="55.0"
                     /tool="antismash"
                     /translation="MRLKVKGDTYYVPDPDGRVYFQNNLGSFQMEGKGIDKWIEKLMPL
                     FNGEHTLEELTTGLSDQRRNHIYHIADMLYQNGFVH"
     gene            complement(15642..15896)
                     /locus_tag="FB479_RS23955"
                     /old_locus_tag="FB479_109246"
     CDS             complement(15642..15896)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FB479_RS23955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FB479_109246"
                     /product="hypothetical protein"
                     /protein_id="WP_164724529.1"
                     /transl_table=11
                     /translation="MQAACFIIVVILGIYTNIDVEIDAVVETDAVVETDAVAETDAVVE
                     TDADVMTDVDVMTDADVMTDADVMIDADPDVGTDVAIGV"
     gene            16163..16870
                     /locus_tag="FB479_RS23960"
                     /old_locus_tag="FB479_109247"
     CDS             16163..16870
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0031012 - extracellular matrix [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012630.4"
                     /locus_tag="FB479_RS23960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109247"
                     /product="matrixin family metalloprotease"
                     /protein_id="WP_142066945.1"
                     /transl_table=11
                     /translation="MSNSLTRRKTAHFSLNVIVQKGAFEDMEIAKSTVKQNVVYAQRYF
                     DRNAEVNGFPWMNLVFHEENDIFENDRLQHSFNSSHDLRDFFIETARAGGWRKTKQRLP
                     CINIYYLTSIPPDGISAGVHIPGAATFCNQRTVEKLSLLLRKWKRASPSEHLALYGIIK
                     HRPSVFLNANAIAPSTLAHEIGHILGLGHSSEPSNLMYPIANQRIRCELTYEQSICLRD
                     GIWKYSHGYFPFL"
     gene            complement(16950..18377)
                     /locus_tag="FB479_RS23965"
                     /old_locus_tag="FB479_109248"
     CDS             complement(16950..18377)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (144-464). E-value: 7e-38.
                     Score: 122.6. Matches aSDomain:
                     nrpspksdomains_FB479_RS23965_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007721934.1"
                     /locus_tag="FB479_RS23965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109248"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_142066946.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.6e-37, bitscore:
                     122.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKREALSNSHSDKLFEQVYEYLLDRIRREEWRAHEKLPSVRTLAL
                     ELNVHRLTVFKAFQLLKQNRHVYVKDKSGYYVQPSSLLPVESMDDPIVSAYVHKSHLSE
                     IHQVQATYQFSKALIEPNLLPNHYFSEYVKKVFDLYPKVLGTYSTTQGDQELREALCSY
                     YISRYHFHLSPDELMITSGSQEAIDLVARVLVKPRDVVLLERPTYSPAIDVFRRQGAKI
                     IPVEIHPHGYDLEQVERLLQKEKPRLFYLNPTFHNPTGYTVPAEQRKRLVELAAKYQCL
                     IVEDDPCRDMYFGDEPPLPFFSYDTEGYVIYLRSFSKYIAPGLSIATVACRPSMMNYLI
                     QAKSLSDSGAPLLNQKIFLHYFFSERMQQHLAKLRIALAIRRDIMEDELSVTDWEWSSP
                     PGGFNLWVKLPDSVPMESLLGKCIEQSITFVPGAICDPLRELSSWIRLSYSYLNEQQLR
                     DGLQRLVSTVRQLDIKE"
     aSDomain        complement(16986..17945)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FB479_RS23965_Aminotran_1_2.1"
                     /evalue="7.00E-38"
                     /label="FB479_RS23965_Aminotran_1_2.1"
                     /locus_tag="FB479_RS23965"
                     /protein_end="464"
                     /protein_start="144"
                     /score="122.6"
                     /tool="antismash"
                     /translation="GTYSTTQGDQELREALCSYYISRYHFHLSPDELMITSGSQEAIDL
                     VARVLVKPRDVVLLERPTYSPAIDVFRRQGAKIIPVEIHPHGYDLEQVERLLQKEKPRL
                     FYLNPTFHNPTGYTVPAEQRKRLVELAAKYQCLIVEDDPCRDMYFGDEPPLPFFSYDTE
                     GYVIYLRSFSKYIAPGLSIATVACRPSMMNYLIQAKSLSDSGAPLLNQKIFLHYFFSER
                     MQQHLAKLRIALAIRRDIMEDELSVTDWEWSSPPGGFNLWVKLPDSVPMESLLGKCIEQ
                     SITFVPGAICDPLRELSSWIRLSYSYLNEQQLRDGLQRL"
     gene            18489..19412
                     /locus_tag="FB479_RS23970"
                     /old_locus_tag="FB479_109249"
     CDS             18489..19412
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017249964.1"
                     /locus_tag="FB479_RS23970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109249"
                     /product="DMT family transporter"
                     /protein_id="WP_142066947.1"
                     /transl_table=11
                     /translation="MVLLNYVIMCLIFGTTFLAIKVGIDAGAPPFFSGGLRFFLAGVIL
                     FSFMLWKKQARLSLLLHKEMFLTGIGLTFGTFATLYWAEQHISSGIAAILSATAPLMVM
                     LLQTGISRQKLPSISWAGCLVAFVGVFLLILPGVTISFSLLWLTGCMAVIFGQIFYSAG
                     TVYSRSVIQRFQDTSPIALNAAQMMYGGAMLLVLSLFTEQVHVESMLTANAILSLLYLI
                     VVGSMMGHTIFYWLVAKTNPVFPSTWLYISPLIALSLGVILYNEPLYLLSFVGGITIIV
                     GIILINMDGLKQLMGKKANKLRDISN"
     gene            complement(19477..20469)
                     /locus_tag="FB479_RS23975"
                     /old_locus_tag="FB479_109250"
     CDS             complement(19477..20469)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012684584.1"
                     /locus_tag="FB479_RS23975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109250"
                     /product="hypothetical protein"
                     /protein_id="WP_142066948.1"
                     /transl_table=11
                     /translation="MDKNPFNRMQDMLRAKPVPKVDVKHKVMAAIRAKENKEEKVVKKK
                     IGLLVTVGMLVGASSVWAGVEMIQLKNEKGEVVYEIRQHTDQEQQRLIQQMPPEEQAKM
                     EARGKMYEHRDEVNNEIINGLKPGTSVAIYWKPTKEEEEIQKNITWSIYKQPYITMVSK
                     PMTYKTWKEMEAAVGKMFTLPAELAGGFRFDEGDVHYEENYEYMVDLEALKAKAIKENK
                     EYAFTEIPSSNKYDFTSVAYKSEKGSVRVEVRIAHEGKTGTNAEALEKIMIGNNEAVLT
                     THASKNSDNLNWITWVKNGTKLKYSVRATEKVASKDELIKIAEQINDTK"
     gene            complement(20450..21016)
                     /locus_tag="FB479_RS23980"
                     /old_locus_tag="FB479_109251"
     CDS             complement(20450..21016)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012684583.1"
                     /locus_tag="FB479_RS23980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109251"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_142066949.1"
                     /transl_table=11
                     /translation="MEKKEIEPLLQAIKNGSLEQFEIIIDHYQQPIFTYCYHMLSHHQE
                     AEVAVQEVLLHAYEHLEQYTTAVSFSTWICRIAHNYCVNVLKRRKLSRWFPFLYKQDHG
                     GSVKEHIDLPNREEVVERIWNRLSAEERSLVFWRVLEEKAYEEIAELLDKPPEALHKQF
                     ERILKKCKRYLPTMEGVAANGQKSV"
     gene            complement(21121..22098)
                     /locus_tag="FB479_RS23985"
                     /old_locus_tag="FB479_109252"
     CDS             complement(21121..22098)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018671953.1"
                     /locus_tag="FB479_RS23985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109252"
                     /product="DUF4367 domain-containing protein"
                     /protein_id="WP_142066950.1"
                     /transl_table=11
                     /translation="MMDKNPFKHMRDMLVAKPVPKVDVKHKVMAAIRAKENKEEKVVKK
                     KIGLLVTVGMLVGASSVWAGMEMIQLKNEKGEVVLKLKQMSMQEQQQKMQQLPPDIKDQ
                     IKNRNAEIFKQLDTGEQIVNGLKPGEAVAIYWQLTKLQLESNPNSTPFVDVRSKPFTYT
                     TWKDMEQKVGHLFKVPTEMGTDFKFVAGEAIYLPSDKYDEKAMKEEQERTKKEYVVQTI
                     PLSDKLRDAEIEYKGQKGSAFLQVSILGDKNKSGGTLAENLEKVMIGDNEAVYSTFAPE
                     NGDTVHSLEWVKNGTNVNYSLRAKMSVSTKEELLKMAEQINQAK"
     gene            complement(22076..22648)
                     /locus_tag="FB479_RS23990"
                     /old_locus_tag="FB479_109253"
     CDS             complement(22076..22648)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012684583.1"
                     /locus_tag="FB479_RS23990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109253"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_142066951.1"
                     /transl_table=11
                     /translation="MEKTEIERLLIEIKAGSLEQYELIIDHYQQPIFTYCYHMLGHRQD
                     AEDAVQEVLFRAYEHLDQYTYSLSFSAWLYRIAYNHCANVLKRRKLSRVLPFLYNRDQD
                     GRNYVEESIDSNYFGEPLERIWKRLSAEERTLMFLRVLEEREYEEIAELLDKKPAALRK
                     QFERILKKCKRYLPTTGGVLNDGQKSV"
     gene            complement(22881..23207)
                     /locus_tag="FB479_RS23995"
                     /old_locus_tag="FB479_109254"
     CDS             complement(22881..23207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016740630.1"
                     /locus_tag="FB479_RS23995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FB479_109254"
                     /product="DUF1904 family protein"
                     /protein_id="WP_047073417.1"
                     /transl_table=11
                     /translation="MPHLIVRGIQAEQMATISEPLAVELAALCQCGTDNFTIECLQTTG
                     VFGGKIVESFPFIEVAWFERGQEVRDQFAQIVTKHVLSLGIPEVEMAFVAYQKESYYAN
                     GEHF"
ORIGIN
        1 cctttgtcgc atgcgataaa tacccttctt ttcgataaat caaggcatac tgccagtcaa
       61 tcaccgggta ggaaatgttg acggtgtgca attgtccgtt attcaagcgt ctcacgatgg
      121 agcgtggaat gagtgatatc cccagttgag tagccaccat ttctccgaca aaatcccata
      181 aagagctcat gtaagcgact ttcggttcaa aaccggacag cttgcacgct tggcgcacca
      241 catcatgcat cgcgtactct tcggtaaaca aaatgaaagc ctcgtccttg agctgttcca
      301 agctcacctc atcgactccc gcgagccaat gctcccgatg aacgatcgcg acgaggtcct
      361 ctgcgagcaa ggggactgct acaaatttct cctgatctgt tggaagaacg gttaatgcca
      421 catcgatgct tccttgctcc atttggattt caagcagctt ggcgctgtat tccttcatct
      481 cgatatcaat gcctggatac tgctttttaa acaaggcaat cacattcggc aagagaaaag
      541 aacccacggt gggcatcatg cccagcttga cccgaccacg ctcgatattt cgcaattctg
      601 caatcgacga cgacatgcct tccatcagct gcaacacttt ggtcgcatag ctgtagacca
      661 tttcccctgc gtctgtcaga tccattttcc gctccgtccg atccagcaga actacctcaa
      721 gctcttcttc caatgccttg atcattttgc tgatagaagg ctgagagacg tgaagggatt
      781 gcgcggcctt cgtaaagttt ttatgtttga ctacttccac aaagtaatgc agctgtcgaa
      841 tatccatgat gccctccgtc ttcgtccaat caaaagagtt agctacagat taccacaggc
      901 gagagtatgc gaaaaagcca ggtgcgcagt cgcgccctgg cttttcctcc agcgtgagtt
      961 acttcacggt tacctgtatt tttacgactt ttccattata cgtagccgca atcgtcgcac
     1021 cacctgcttt tacagccgtg atcttgccat ccgctacagt cacaacggaa ctgttcgtgg
     1081 agatccagtc tgcatcggtt gtgacatcga ccttggtttt gtcggtatag acagcagata
     1141 ccttcaagtc ttttgattcg ccgactttga gtgtagcctt cttcgtgtca aattccagct
     1201 tggagatgac agcagattct acagggattg agaccgtctt tccaccgtac gttgctttga
     1261 ttctcgtttt gccagagcct acagttttca caactccgtt ttcaactgta gcgacctttt
     1321 catcgtcgga tgtccacttg gctttgcttg ttacatctac tttttctttg gtagacaagg
     1381 tagccaacag cgttatcgac tgggtagtgt ctggacgcag atacagcttt ttcttatcac
     1441 tgtccagctt ggagacgaca tccacctcta ctggaatgga tacgcttcta tcaccgtatt
     1501 tcactttgag ctttgctttg cccgagccta ctgccgtaac caaaccattt gctaccgtta
     1561 cgatttccgt atcatcgctt tcccactctg catgagccgt tacatcagcg gtagacttgt
     1621 ctgagaaggt tgctgttgcg tttacctgtt tcgtgcctcc cacgctgaga gccagtttct
     1681 tctggtcagc agcgagcttg gaaatcacat cgatctcaac agggacattc acacttttgc
     1741 ccccgaagct tgctttcact cttgttttac cggaactaac tgctgttacc aagccttttt
     1801 caacgctagc gatgtcactg tctgaggaag tccactctgc ttgctgtgtg acgtcttccg
     1861 ttgttttatc cgtgtattgc acgcggacgt tcaattgctg cgtccccgct tttttcaatt
     1921 ttactgtctt tgtatcaacc acaagcttgg aaatcttctt ctgcgtactt gttgtcgcag
     1981 aatttgccaa tgccggtact tggccgacac tggaaaagat cagcccaaca gtaacagccg
     2041 tagcgagcat acctttttgc caatttttca tgctcacatc cctctcctct ctacttttcc
     2101 accattttct atatcggcta aacagccgta cttgtgaata caaaatggca aagaaagtca
     2161 tgattcttct gcccatgtcc ctgccaaggg agcaaagtgc tgcatcgcca aagctcctgc
     2221 tcccatcacg attgcctccc ccttcaattc ggaaggaatg acgcgaaatt tccccttgaa
     2281 tggctcccag atcacttgat cgctatgctc ctcgaccaag tcaatgattt cgcggtaatt
     2341 ctctaccaaa tcaccgctta caatcaccgt atctggattg tacatgcata caatattgtt
     2401 aatcgtgatt ccgaggtaca acgcagtacg agagacgatt tccttcgccc agcgctcttc
     2461 gtttctcgct gccgcgaaca cctgacggac atcactgaca tccttcactc gacgcgcttc
     2521 tatgatcaaa gaattttcgt ctatgtatgt ttgcaggcat ccgcgctttc cacattcgca
     2581 cagattccca ttcggatcga gcgtcgtatg ccccagctct cctgcgctat tggagccccc
     2641 gcgaaacact tcgccattga taatcaacgc agaaccgata cccgtgccaa tgccgatcaa
     2701 ggctgtcttg ttcgagcctt tagccgagcc gtacaagtac tccgagagaa ttttcacctt
     2761 caaatcgttg tcgataacgg ttttgatttt cagccttttt tcaatcaggc tggcaaacgc
     2821 tacgtccttc cattccagcg tagtggaaag ctgaacaatc ccttgctcat aattgatcac
     2881 ccctggcatc ccaataccga tcccgaccac tttttctatc ggaatgcctg tctggttgag
     2941 catcccttca atctcgttac aaatcagttc agccgtctct tccggtgtag aatcctgcgt
     3001 cttatgatcc atccggtgct gtgcaataat cgcttcgcta aagtccatga ttccaaagct
     3061 gatgcgcttt tttgccatgt ccacgccgat cgtataaatg gctcccggct cgatgtcgag
     3121 catgattgcc ttcctgccca cacctgatga ggtaagctct gtctctcgaa tcagtccttc
     3181 ttcgcacagc tcgctgacaa atctgccaat cgaggtagca ctcatccggg taattttggc
     3241 gatttctgca cgcgatatcg gtctctgctt tttgataatg tcgaggatca tttgcttgtt
     3301 atgctgcttg gtgacgtcct gatcttgctt catgattttt ttcatcctac aaaactccca
     3361 tcttgcttga attcccggta gtattcctgc gcgattattc tcacactacc tgtcgccatt
     3421 tattacgtca actgggccaa acaaaaacca tccgaatcac ctcggatggt tgctacgatg
     3481 ctatcgcttg ttgttgttca aatcatacgg agtctcttgg taaacgtaat agtttaacca
     3541 gttggaaaac atcaaattcg catgtgcacg ccaagtgaca ataggctcgc gacttggatc
     3601 gtcctttgga tagtaattgc gcggaacagc aatgtccaag cctttgttca catcccgctg
     3661 gtactcatct tgcaaggtag tcggatcata ctcggaatgt cctgtcacaa aaatttgtct
     3721 gccatccctc gtcgctacga tgtaaacccc tgcttcatca gactcggaca aaatctccag
     3781 ctctgacact tgctcgatgt cttccctgcg attttcggta tgcctggaat gcggaatgtg
     3841 gaaatagttg tcaaatccgc ggaacagctt cacattttgc ttattgagtg tatgagggaa
     3901 gattccgaac attttttctg gcaaaggatg cttcggaacg ccaaagtggt ggtaaagacc
     3961 cgcttgtgct ccccaacaaa tatgcagggt cgaagtgacg ttctccattt tccaatcgag
     4021 gatttctgtc aactcccgcc agtacgtgac gtctgtgaac tcgagctgtt ccacaggcgc
     4081 tccggtgatg atcatgccat caaatcgctg gtcacggatc tcctcaaacg ttttataaaa
     4141 catcgataaa tgttcttccg acgtattttt ggacgtatgg ctggacatgt gcaaaagcac
     4201 gatttccacc tgtagcggcg tattccccag gaggcggagt aactgtgttt ccgttgtttc
     4261 cttcactggc atgaggttga gaatgacgat cctgagcggt cgtatgtcct gtgtgaaggc
     4321 acggctatcc ttcatcacaa aaatattttc ttgggcgagt atttccgttg caggcaattc
     4381 gtcgggcaat ttgattggca taaagatccc cctttccatc ctttgaacac aggtagaaaa
     4441 acattaatcc gacaaattcg acaaaaatac tagccttcct gctaatcaca caggggaaaa
     4501 cgaaaaaatc cccttgcaag caagttgcaa gaggtctctt cccttaaatc cagccgcgcg
     4561 cttccatcgc ctcggtaatt cgcaaaagcg agatcatata ggctcccgtg cgcaagtcca
     4621 ccttgtattg atcagagagt tctttcacgg cgcgataggc gttaatcatt gtcgtttgca
     4681 gcttttcgtt tacctcctgc tcggaccaat agtaattcat caggttttgc acccattcaa
     4741 aataagaaac cgtcacgccg cctgcattgg cgagaatatc gggaataacg ataattcctt
     4801 tttctcgcaa aatggcgtca gcatccggtg tagtaggtcc gtttgctgct tctgcaatcc
     4861 acttggcttg aatactgtgg gcattcgctg ctgtgatgac attttccaac gcggccggga
     4921 ttagaatatc cacttcgagc ttcaacagct gttcattaga gatgaccgta ccacctacat
     4981 actccaaaat ggtagcattg tcttttaact gtcctacctt ttctatgtcc aagccagcag
     5041 catcataaat gcctccgcgt gagtcactga ccgccacgat tttgaagccc agctccgtca
     5101 aaagtctggc agcaattctt cccgcgttgc caaagccttg aatcgcaacg gttgtttgtt
     5161 ccggctttcg tccagaatct tttaatgcct cgagtatggt aaagacacat ccgcgggcag
     5221 ttgcttcgtt tcttcctttg gaaccgccga cactcagcgg ttttcccgtg atgactcccg
     5281 gagaataggt gcctcttaat cgactgtacg tatccatcat ccagcccatg atctgcgggg
     5341 tcgtatacac atcgggtgca ggtatgtctg tctcaggtcc gacaatatca gcgatggctt
     5401 ccatgaagcc gcggctgact cgttccagct cgcttttgct gaattcgtgg ggatcacata
     5461 tgacgccgcc ttttcgacca accacgccac atttgaatga catccacatg gagagcgcct
     5521 tgacttcatc catcgttaca tccggatgaa agcgaatccc tcccttggtc ggtcctaccg
     5581 catcattatg ctgagatcgg tagccttcaa agacacgcac gctgccatcg tccatcttga
     5641 caggaaagct gacagccaat actcgtttgg gtcgctttaa aatttctaca gcatcggtcc
     5701 gcaatcccaa caatgccgct gcagcgtcaa tctgtttctg cacaatttcg tatggattca
     5761 ggttttcttt ctctacagta tgtagcatct ctcttcctcc ccaatacttt tcacatgcgt
     5821 tttctacatc accttggcgc agagctaaag gatgaatgga gtaattatat acgattcaag
     5881 taaattcaga caatttattt tcgttgtttt cacattattg tgttattttt ggtaaacaaa
     5941 taaaaaacgc ccgatgcatc ctcacgacac atcagacgtt tttctcttat tttttcaaat
     6001 acgccttcat cagcttcgtt tttgtctccc acatctcttc gctgatgtgc agacggtaat
     6061 gctccggatt cagcatgcgc aagtattcag gccagaacag cttgagttgc tcacgatggt
     6121 agttgcgaat ctcttggaga gtcggcaatt cataaaccag ttccccatcc acaaaaaccg
     6181 gaacgagcag cgactctgcc tggtagttct ccaaatgctt gctcaaatac gtatggctcg
     6241 gatggaacaa atggagaggt gctccctctt cgactgttgt ctcatgcggg aagcacatgt
     6301 agtcagcaat cgctttgcct gtttccggat caatcaatcg gtacatgtct ttgatgcccg
     6361 gcgtcgtgac tttttcggga ttcccggaga ttttgatggt cggctgatat tttccgtcgg
     6421 cgccttcgcg cgctaccagc ttgtatacgc caccgagcgt cggctgatcc gctgccgtga
     6481 tgagctgcgt tcctactccc cagctgtcca cgcgtgctcc ctgtactttc aggttcataa
     6541 tcgtgtgctc atcgagatcg ttggaagcaa caattttcac atcgggcagc ccggccttat
     6601 caagcatttc acgcgttttg atggacaaat aggccaagtc gccactgtcc agtctgacgg
     6661 cagccagctt cttgccttcc ttctccattt gctttcctag cttaatcgca ttcggcacgc
     6721 cgcttttcag cgtatcgtag gtgtctacca acagagtgac ctgccctggg agtgcttttg
     6781 caaaccgctc aaaagcctcc gcttcgctct cgaagctctg tacccaagcg tgggcgtgcg
     6841 tgcctttggt cggaatacca aacattttcc ctgccagcat gttcgaggtc gcatcgaagc
     6901 ctgccaaata agctgcccgc gtcccccaca gcgcagcatc tgcctcctgc gcccttcttg
     6961 ttccgaattc catgagaaca tcattgcctg ctacgttttt aatccgcgaa gctttggtcg
     7021 caatcagcgt ctggtagttc atgtagttca acagggccgt ctcaaccagc tgtgcctcca
     7081 tgacacgccc ctctacgcga atcagcggct cgttcgggaa aaccacggtt ccttccttca
     7141 cagagtagag cgagccctta aaacgaagct ggcgcagctc ttccaaaaac tttggatcgt
     7201 agttctcctc ttgctcactc aaatacttga gatcgctttc ttcaaagcgc aaatttttta
     7261 tataggaaat aattcgttcc aatccggcag atacagcgta tccgtttcca aaaggcagct
     7321 tgcggaaaaa tgcttcaaaa acgaccttct gattgtgtgt tccgttcacc caatgggcgt
     7381 acatcatgtt tatttgatat ttatctgtgt gtagtgccac accaaatgat tgcatgtcac
     7441 tgaggcctcc tgtgttttcc tttccatcat cataccagaa gctacggctg gtgcccatcc
     7501 gctgtggagg atattaggga atgtggtata gtatggggat aaaaagagaa gcaatcgtac
     7561 aggctgggag tgagcattag ttgaacagaa aaatcgttac gattagtaaa ggattgccta
     7621 aaagtaatat gtacaacggc aaagaatatc tctccggcat ttggaaggag gaagcaggcg
     7681 agctcgttgt ccgttccgag aaaattgatg aagacgatat tgcgaatcca gagtaccacg
     7741 gcggcccaga ccgcgtcgtc tgtgcgtatc cttttgaaca ttatgcccat tgggagaagt
     7801 tattcggcca acctctgacc aatgcagcat tcggagaaaa tctcacgctc gttggcatga
     7861 ctgaagagca ggtctgcatc ggggatgtgt atcaattcgg tgataccatc ctgcaagtga
     7921 cccagggcag atatccttgc gcgaccatca acaagcgcaa caacaataac cagctgctca
     7981 aagcggtggt ggaaatgggc tatacgggct atttcttccg tgtcttgcag gaagggacga
     8041 ttaagccaga ctcgaagatt accctcgtca ctgcgcatcc aaaacaagta acggtagcgt
     8101 caattcacca cttatacttc cacgacaagt caccatccca agagacgata cagcgtatgc
     8161 tcgaggtaga ggaattggcc cagccttggc gaaaaaaact actggaaaaa ctggaaaagc
     8221 agcagcaata gcgaaaggaa cgtctcatga gaattaataa gttcatcagt gaaaccggca
     8281 tttgctcgcg aagagaagcc gataaattaa tcgaggccaa gcgcgtgacg atcaatggtc
     8341 aactcgcgga attgggaagt acggctgcgc caggagatga tgtgcgcatc gatggacagc
     8401 cgctcggcgc caaaaagaaa gatgtctaca tcgccttgaa caagcctgtc ggaattacgt
     8461 gtacaactga actgcacatc aaaggcaaca tcatcgattt cgtgaatcac ccggagcgga
     8521 tttttcctat cgggcgtctg gataaggatt cgcaaggcct catcctgttg acaaatgacg
     8581 gggatatcgt aaacaaaatt ttgcgtgccg agaacaatca tgacaaagag tacatcgtca
     8641 ccgtagataa gcccatcacg gcgaatttct tgcacggaat ggcaaacggc gtacgtattc
     8701 tcggaacgac cacaaagcct tgcaaagtaa ccaaagtcag cgaccgtgtc ttcaatatcg
     8761 tgctgacgca aggactgaat cggcaaatca gacggatgtg tcaggctttt ggttatcagg
     8821 tgcgaaagct tgaacgggta cgcatcatga acatcacact agggaatttg aaattagggc
     8881 aatggcgcaa tctgacggcc aaggaattga ctgatctgaa taaaagcttg tgaaataagg
     8941 acagattgga gttaggatag tggctcctct gtattttctt tcgtcaacat acgtgaatca
     9001 tttgctatcc gttcaatatc ctgttatgct agtaaagaat tatttttgtt cgaagcaacg
     9061 gatagcgtag ataacaaatt atcgtcttga tgatcctgag agcaaggata gtaatatatg
     9121 tgtgctacac actaggaggc aacaacaatg gaacaaggta cagtaaaatg gtttaacgca
     9181 gaaaaaggtt ttggttttat tgagcgcgaa ggtaaagaag acgtatttgt tcacttctct
     9241 gctatccaag gcgaaggttt caaatccctt gacgaaggtc aaaaagttac ttttgacgta
     9301 gaacaaggcc aacgcggacc acaagctact aacgttcaaa aagtttaata tagccataca
     9361 caaaaaacag actcctgtaa ggggtctgtt ttttggtttt ctgaaacaca aataaaaaac
     9421 cctactcgcg taaatggagt agggaatgct acaggaacag taaatggtag actcagtata
     9481 acacagtact tatctcttcc tacaaatttt tgtattttca aatacggatt attcaaccgt
     9541 aggtagttta gaacgttgaa tatgcgtaat ttgccgcaca agcagaggct tcatacaccg
     9601 tttctcccaa aatgctagac gcgatgagtg ggcagcactc gccagccgat agcctgtaca
     9661 atgtaacctc tctcccatcg ctgctcagtt tgaaaatgcg aaccagccca tccaagatca
     9721 atggcgcatt ctcaaaaaac tcgccttcat caatcgtaaa gttggctgga accgtagagc
     9781 tggtgaatca tctcgatcaa gtaagcaaat cgaaataagt tcgtggtaat atccccttac
     9841 agtagacaac gtaaaaaaga catcggctga agatggattt acacgttgtg atcggagggg
     9901 gattttttca tggggaaaac gaaacgaccg ctccccagtg aaatatcggg aaatggtcgc
     9961 tgcgtaattg atgtctgttt acgtgtgctt cagctccttc ctatacgtac aaatgtccgg
    10021 ttaacgtatt gggtaaacga tagggcccaa caggtacttg tattaaacag ctttggttta
    10081 cattcgtgat tttgtagatt ttatcgcatg tttttgcatc ataatcgaga agcggatggc
    10141 ctgccaatcc gatcgaagaa gctaccaaca gtaatttttg tacaagtata cccgcttcca
    10201 tttgttgaat acgatatcct ctgtatccga gtttatgtct gtagtaatga tagtccccta
    10261 ccacatgcag gcagatcgga acatcgaagt cgctcatagt cattgcctgt tttaatatgg
    10321 ggcgatggtc tccaagacga atgagcctta atttatgaga aagataatca taataatagg
    10381 cgccagcggg aataccctcc acagaataga gacagcagta caacgaaact cgagacctcg
    10441 gttgttcttg gatttcgggg atatctattc gatccagatc atttcggtag aagaaagcat
    10501 ttgtcgcctc acgcaaaaga gtggctaatt gctgttgact cacttcgcgt aaaatgaagc
    10561 gctcaccagg tgaaaacctc tttcggctcg cctccataag atcccagttt aaaggtttta
    10621 cgtttggtaa tgccagagaa ggacctccaa agacaggctt tttttctccc cgtacccgat
    10681 gaaagcagtc cgttgattcg aactttgatg cctcattcaa ctttatcagc atgggatatt
    10741 ttctaatcct tcgagaacgg atataggaat gatgctgaac agcgggtaac ttctgataca
    10801 attctttatc ccagacaatt gccattcctt cacgcttatg ggcaaaccaa ttgatatctg
    10861 attttatcga gagaggaatc actgcatata cgctttcttc ccattggttc agccccagca
    10921 gatgattgac ggctcgatcg agaaattgat agtaaacacc tgttgtaaaa ccaaaccttt
    10981 tcgctgcttc aagcagctgg ccaatcagta cccctgcatc caaaccttgg aggcggtacg
    11041 ataaattatg atacttaaag aaatttttcc aaaacattgt cgatacaaat acggcagcaa
    11101 aacactctga catgtcgcaa tagccaccca gagccattgc cagatatgaa tcgcaatttc
    11161 ctttgcgcag caacaccaaa cgatgatggg cagcgtcgta atggtacact ccctcgggca
    11221 agtcatctat gtttacatac acgtataatt cgcttggata caaagcccct ccagacggaa
    11281 caaatcttcg gaataactcc tctgatcttt ggtcgaagaa atcccagtca ttacctggat
    11341 cagacactcg ggtaagacca aatgtgaccc agagaaaatg gccaatatca cgaatggttg
    11401 gcttcgatga ttgtttattt ctgccgtgtt caagagacag cggaacttct aacgaaagcg
    11461 gcacgacagg cagttcgcga tagatcttat aaaccagagg ggaatcttcc caatctactg
    11521 tccagtcggc ggggataatt ttttcgatgt catacagcag attgtgcaaa aatacatccc
    11581 tgcgcatact ttttcctcct acttcaagac ctatggaaat ggatgcggat gcggattcag
    11641 ttgttcatat gtcaggggat gtttggtata gccaagctgc atgggtacgt tcaagacacg
    11701 atccagtcct gttacgcggg ttaagtgata gccaaacgtc atcggcagca tcccagggat
    11761 cagaactttc acgctgtaca gttcattcct gatcatttct ggtgtcgtct ggttaacgac
    11821 tatcacttcg aggtttaatt gcttaaaaat ctgcagaatg cctttcaaat catccgtcag
    11881 gtcatgatga cctgcctgca gcttaaactc ctcgtcaaat gttcgcatgg gccgatcatc
    11941 atgaagcaaa aagtgcagtc gctcttccgc ttcaggcaga ctgtacagca taccatggtc
    12001 ttccatgctt tgcacccgga agggatcgtg cagcatttgc agaaactctt cccgatgcgt
    12061 ttcatatttt tcatccagtg ttaacagcat gtcggccagt tcatgcaccg cagtttttac
    12121 agctcgcaac ggatccggat gagacccggc ggcacagacg agattgactc ccttctgttt
    12181 cctgtttttc gtaatggccc aaacacttgg tatcccattc tccattgtcg cgttatacaa
    12241 atacaaatcg taacctgcca ctgcttttat tcgctctatc atcaagagca attctttgtc
    12301 tttcgcagat tcaggatcaa gccgcggtaa aggcagttgt gcataccatg tcaaaagaaa
    12361 tgcgtctcgt tccaccactt ccaatatacc gtagaaaatg gcctcctcta gacacctgcc
    12421 taacgcgcag ccattggagt tttcatagac gaagtcatct ttcaggtcgt agtaggcaat
    12481 cgattctggt accaagattg gcttctcctt aaaaaatgaa taaccccata cccaattcat
    12541 gggccgtttt ggatcaaatc tttggaaagg ataatcagga cttgcatatt gctcctccga
    12601 atgcagcccg atcttcagcg ggttgagcgc gtggtctttc accttctcat aactgtcgca
    12661 gatgaccgtt cttttgcctc gtggatgcag acctgcgtat cgctccaatg cctccaggat
    12721 ggctgtcagt tcactctgct cataagaaag agttcgcccg gctgctcctt cattagacgt
    12781 tatcatcggt agattcacgc tcatgacggc aaatggggtc aggtggtctt tggttttttg
    12841 gttgatcatg ccagttcgaa aatcgagata ctcctgaatg aggacttcct taaaaacatc
    12901 tagcgaacag attcgataac tgttgggatt tgcctttggt cttggttgaa gagtaatacg
    12961 tgcggcctca ggtgtatcct caggcaattc cccacatacc tcacatattg gatttggcaa
    13021 aaagaagtgc tctgaggtcg ccagagtttg caagtttacc aaatggattc ttgttctttg
    13081 ttctgtatat gggcgactgc cctgtaacac tctttgcgct tccgctgtga tcatgttcgc
    13141 caattggtac attcccgtat ttgatgccca tgcatcacgc tgtcgtttct tttgattttt
    13201 tatctggagt tgaatttctc tcagatctct ccggtttttg cgggtcatca gtcttcggaa
    13261 gtcggcacac tgcggacatc cttgcatacg tggtcccacg agtggtccta ctacgccctc
    13321 tccaaatgaa acaaagcccc ttaaccaagg aatgccagcc ttcttgaaca cctcttcagc
    13381 ctgcagatga atggaaggat gccagaaatc atgcagtact aaagccaatt ccacctcttt
    13441 gggtatatca gccttacaat caggctgctg cacgacactg tattgactgg acaggtttcg
    13501 atatacgaaa tccgctaaca atccctctcc gacaatcatc aggactgtgc tcatcaggat
    13561 tcatcctttc gcaacagcac accaaatacc cctgccaatt cctctttaaa gacttgctcc
    13621 aattccaatt cacaaacgaa cagctcttta ttgtttcgtc gcaaagagga caaggcggct
    13681 tgcaacattt cggagtgtgc tgcctcttca actgtgggga tgaccaaact gtgtggaagc
    13741 ttttctttta ctacaatgga ggacggatta atcccatatg tcgttgtttg gctaagagat
    13801 gggttatggt ttacccataa cgcctgctgc aatacggtgc gcaatcccat agtcagatgt
    13861 aagcatacgc tgtaatacca gcgatcattt gtgcctatcc agactaccgg gaatcctgat
    13921 atttcctccc ccaggcatac cgtcggtggg ccgttcatga ttgtcagagc ctgcaagtaa
    13981 aaaagagaat gtttatcttc tattgagctc agctcaactg gataaacagc agtttggtgg
    14041 ttttcgagct gtttacgcag ctctgctgtc aaactctttt gcaatcctcg ggtaacggct
    14101 tccggaactg tctcacccgc gcctattcca ataaattcct cagtcccaaa tagcggttta
    14161 gccattctcg atgcatacgt ttcaattccc gccaatcccg cttcacgcct agctccatca
    14221 tgcgtcaaag ctgaacaaac gatgtctgca agtaactcta ccggaccttc ggataaggga
    14281 tcaactacta ccactcggca ttgcgccaat gggagttgtt ccaaatcccc ctcgtcccaa
    14341 gtatgaaaaa ttcctgtttg ctccgatgtt aacgaaccaa agaatgctgg caaatcatat
    14401 gagccatttt gaggaagacg ttgttcaaaa agtagattcg tgtccttcac ccatttcaca
    14461 cgtgcaccac cagtcaccag agggtgaggg gtaaacggat gccactctcc ttccatcgtc
    14521 tccaaattca tgagaaagat tttattttcc tgcccagatg tccctgtaat ggtcttcagc
    14581 aattcaaaca caacgatgtt tgctaacatg gcagcggaaa tgggggaata agcactgaaa
    14641 caagagccgt tcttgaatga agatcggtgg attcggcgcc tggccgattc aaaacatcca
    14701 tctgcatctg gacgtaaaac tggccccgca attcccactt ggtcgtggta aatagctgga
    14761 ataaagattt tgttttgttc cttgcaaatc gaataaagca cccgcaattc ctcaaggtcg
    14821 ccttcttgtt gtacatataa gacaacttga aaagtctgca cagccttctg ccaaccatcc
    14881 cgatcatttt tttgcaggta aatttcctcc agctttacct cggagtcctc ttttcgagca
    14941 tgtgctgcca attcccacaa acgttcccga ttggtctcca tggaatgggt agtggctatg
    15001 tatatggcag gcaatcctga ttccaacaat gctgcaacca aagcagaaag taggggacca
    15061 gagcctacgg ccagcacttt ggtttgacgg tacaactgaa aacgataagc agcggaatca
    15121 gtgaagctgt tcaaaaattc tatctgagga gcgtatttct ccataatttc cttagataac
    15181 tggtgtgaaa gctgactgct ccaatcgtgg acaaagccgt tttggtacag catgtctgca
    15241 atgtgatata tgtgatttct acgctggtca gacagcccag ttgtcaattc ttccaatgta
    15301 tgttccccgt taaacaaggg catcagtttt tcaatccact tgtcaattcc cttcccttcc
    15361 atctgaaatg atcctagatt gttttgaaaa tacacacggc cgtctggatc tggaacgtaa
    15421 tacgtatccc cttttacttt tagtcgcatg gatgggttga cagacgtcat tttatgcctc
    15481 ctcccgtgcc ctgatttcgg aaatatgtct ttcacaacta ttttgatctt atgctctgca
    15541 atttgtcctt cttgtcaaaa aatgatgggg aagaaaaaaa gccataaccc acgataatca
    15601 tggattatgg cccttctatc agcatttcta tatcttaccc tttagacgcc tatcgcaaca
    15661 tcagtcccaa catctggatc tgcatctatc ataacatctg catctgtcat aacatctgca
    15721 tctgtcataa catctacatc tgtcataaca tctgcatctg tctctacaac cgcatctgtc
    15781 tctgcaaccg catctgtctc tacaaccgca tctgtctcta caaccgcatc tatctccaca
    15841 tcgatattgg tataaatccc cagaatcact actattataa aacatgctgc ttgcatcgat
    15901 cctgcttact tccatacttt caaaatctct cctgaaatca ctgctcactt gttttcctcc
    15961 ctttttcatg tcctaggaca tgacttaata accctaactc tcccaacgta tgatcaacaa
    16021 aacctactac caggggagtt agagtacttc aattcgtctt gctgcaagat attctcgaca
    16081 caacttgttc gtcacttcat ttcctcaatt tgggtatttg ccaagcgcac aaaaaagtcc
    16141 aggaagaaaa gagtgatcaa caatgtctaa ctctctaacg aggagaaaaa ccgcacattt
    16201 ctcattaaat gttattgtac agaaaggtgc atttgaggat atggaaatag ccaagtctac
    16261 ggtgaaacaa aacgttgtct atgcgcaacg ttattttgat aggaacgctg aagtgaatgg
    16321 ttttccatgg atgaatctcg tgttccatga agaaaatgat atcttcgaaa atgacaggct
    16381 tcagcatagc ttcaactcat cccacgactt gcgggatttt tttattgaaa ccgctcgtgc
    16441 aggaggttgg agaaaaacaa aacaacgact accttgtatt aacatctact accttacttc
    16501 aatccctcct gatggtatat ctgctggcgt tcatataccc ggtgctgcaa cattctgcaa
    16561 tcaacggaca gtcgaaaaac tatctttgct gctgcggaaa tggaagaggg ccagcccttc
    16621 agaacacctt gccttgtacg ggattattaa gcatcgccct tccgtttttc ttaatgcaaa
    16681 tgctattgcg ccatctacat tggcccatga gataggtcac atcttggggt taggccacag
    16741 ttcagaaccg agtaacctta tgtaccccat agctaatcaa cgaattcgat gtgaactaac
    16801 ctatgaacag agcatttgtt tgagagatgg aatatggaag tacagccacg ggtattttcc
    16861 gttcctatga caatcacaaa acaagaaaaa agcccacccg ttatacgagt gggctacagg
    16921 ctgtcgacca tcatgtcagc agcctttctt cattccttta tatccaactg gcgaaccgta
    16981 ctaacgagcc tttgcaaacc atcccgcagc tgttgttcat tcaaataaga ataactgagg
    17041 cgtatccaag agctcagctc tcgcagcggg tcacagatcg caccgggaac aaacgtaatg
    17101 gattgctcta tgcatttgcc cagaagactt tccattggga cggaatcagg cagctttacc
    17161 cataaattaa agcctcctgg tgggctggac cactcccagt cggtcactga cagctcatcc
    17221 tccatgatat cccggcgaat agccaatgca atccgcaact ttgccaaatg ctgctgcatc
    17281 cgttcggaga agaaataatg caaaaaaatc ttttgattca acaggggtgc tccgctgtct
    17341 gacagtgatt tcgcttgaat caaatagttc atcatagatg gacgacatgc cacagtggca
    17401 atactgagcc ccggcgcgat gtacttgcta aagctgcgca aataaatgac atacccctcc
    17461 gtatcgtaag aaaaaaacgg cagtggaggt tcatcgccaa agtacatatc gcggcacgga
    17521 tcatcctcta cgatcagaca ctgatatttc gcagccagct ctaccagtct cttccgttgt
    17581 tcggcgggaa cggtatagcc cgttggatta tgaaaggtcg gattgagata aaacaggcgc
    17641 ggtttttctt tttgcagcaa ccgttcaacc tgctccaaat cataaccatg cggatgaatc
    17701 tcaaccggaa ttattttggc gccctgtctt ctgaatacat cgatggcagg actgtaagtg
    17761 ggtctctcca gcaacacgac atcacgtggc tttacgagga ctctggcaac caaatcaatc
    17821 gcttcctgcg aaccggatgt gatcatcagc tcatcgggtg acaggtggaa atgataacgg
    17881 ctgatataat agctgcacag tgcttcccgc agctcctgat ctccttgtgt ggttgaatag
    17941 gtacctagca cttttggata cagatcaaac actttcttca cgtactcgga aaagtaatga
    18001 tttggcaata aattcggctc gatcaatgct ttggaaaatt gataggtcgc ctgcacctga
    18061 tgaatttcag aaaggtgact cttatgcaca taggcagaaa cgattggatc atccatcgac
    18121 tctactggca gcaggctgct cggttgtaca taataccccg acttatcctt cacatacaca
    18181 tggcggtttt gttttaataa ttgaaatgct ttaaaaaccg tcaggcgatg cacattcaat
    18241 tccaacgcca acgttcgaac agaaggaagc ttctcgtgtg ccctccactc ttcgcgtctg
    18301 atccggtcca gaagatattc atacacttgc tcgaacagct tatcagaatg actatttgaa
    18361 agagcctccc ttttcatgca agctcccccc tttcccccat gataaatcac tgaccttcac
    18421 atctgttcta ttccatatta tctgttctat tcccttccct ttatgatgag gaaaagggag
    18481 gaatcataat ggtactgctt aattatgtga tcatgtgctt gatattcgga acgacttttc
    18541 tggcaatcaa agtcgggatt gatgcggggg cgccgccgtt tttctcagga ggacttcggt
    18601 tctttctggc aggtgtcatt ttgttttcgt ttatgctctg gaaaaaacag gcgcgactat
    18661 cgctgctgct tcataaagaa atgttcctta ctggtatcgg tttgacattt gggacatttg
    18721 ccaccttgta ttgggcggag cagcatataa gctcaggaat cgccgcgatt ttatcggcaa
    18781 cagcaccgct tatggtcatg ctgcttcaaa caggcatttc tcggcaaaag ctccccagta
    18841 tttcgtgggc gggttgcttg gttgcctttg ttggtgtctt tttgctgatt ttacccggtg
    18901 tgaccatctc attcagtctg ctttggctta cagggtgcat ggcagtcata ttcgggcaaa
    18961 tcttttattc tgctggtacc gtttactccc gtagcgtcat ccaacggttt caagatactt
    19021 cacccatcgc tttgaatgca gcacagatga tgtatggagg agccatgctg cttgtattat
    19081 ctctgttcac cgaacaagtg catgtcgaat cgatgctcac ggcaaatgcg atcctctcgc
    19141 tcctgtactt gatcgtcgtg ggttccatga tggggcacac catattctat tggctcgttg
    19201 ccaaaaccaa ccctgtgttt ccatccacgt ggctctatat ctctccgttg attgccttaa
    19261 gcttgggcgt catcctgtac aatgagccgc tttatctcct gtcgttcgta gggggaatca
    19321 cgattattgt cgggattatc ctgattaata tggatgggtt gaagcagttg atgggaaaaa
    19381 aggcaaacaa gctacgtgac ataagcaatt agagatagaa aaggagtacc acaagccaaa
    19441 ctggcgcttt gtggtactcc tcttttggga atatggttat ttcgtatcgt tgatctgctc
    19501 ggcgattttg atcaactcgt ctttggatgc cactttctcg gtagcacgca cagagtactt
    19561 cagttttgtt ccatttttca cccaggtgat ccaattcaga ttatcgctat tttttgaagc
    19621 gtgcgtcgtg agaaccgctt cattgttgcc aatcatgatt ttttccagtg cctctgcgtt
    19681 tgttcctgtt ttgccttcat gagctattcg tacctctacc cttacactac ctttctcaga
    19741 cttataggcg acactggtaa aatcgtactt gttgcttgac ggaatttctg tgaaggcgta
    19801 ttctttgttt tctttgatgg cttttgcctt aagtgcttcg aggtccacca tgtactcgta
    19861 gttttcttca tagtgtacgt caccttcatc gaaacggaag cctccagcaa gctcggctgg
    19921 aagcgtgaac atcttcccta cagccgcctc catttccttc caagttttat aagtcatcgg
    19981 cttagatacc attgtgatat acggttgttt atatattgac caggttatgt tcttttggat
    20041 ttcttcctct tcttttgtcg gcttccagta tatagcgact gaggttccag gcttcaagcc
    20101 attaataatt tcattattga cctcatcccg atgctcatac attttccccc tcgcctccat
    20161 tttcgcctgt tcctctggag gcatttgctg aatcaatcgc tgttgttctt gatcggtatg
    20221 ctgccttatc tcgtaaacta cttcgccctt ctcatttttc aactggatca tttctactcc
    20281 cgcccatacg gaagacgctc ctaccagcat acctacagtg actagcaagc caattttctt
    20341 tttcacgact ttttcctcct tgttttcctt ggcacgaatc gctgccatga ctttatgttt
    20401 gacatcgact ttcgggactg gcttcgctct cagcatgtct tgcatgcgat taaacggatt
    20461 tttgtccatt agcggccacc ccttccatcg ttggcaaata acgtttgcac ttttttaaga
    20521 tacgttcgaa ttgtttgtgc agggcctcag gtggtttatc cagcagctct gcgatttcct
    20581 cgtacgcttt ttcctccagc accctccaaa aaacgagtga ccgttcctca gcagacagcc
    20641 gattccagat acgctccaca acctcttctc tattagggag atcgatatgc tcttttacac
    20701 ttccaccgtg atcctgtttg tacagaaagg ggaaccaacg gcttagcttt ctgcgcttta
    20761 acacattcac acaatagttg tgagcaattc gacagatcca tgtcgagaag gatacggcgg
    20821 tcgtatattg ttccagatgc tcgtaagcgt gaagcagaac ttcctgtaca gccacttccg
    20881 cttcttggtg atgggagagc atatggtagc agtatgtaaa gatcggttgc tgatagtgat
    20941 caatgatgat ttcgaactgt tcgagagagc cgttttttat tgcttgcagc aagggctcta
    21001 tctctttttt ttccacgttt tgccctcctt tcactgtgaa taacaatcgg gattccctga
    21061 atgtgacata tatttcaaaa cccccatcat ggcatagcac ccacgatgag ggaatttcca
    21121 ttatttcgct tgattgattt gttccgccat tttcagcagc tcttctttcg tgcttacact
    21181 catcttggct ctcaggctat agtttacatt tgtcccattt ttcacccatt ccaaagagtg
    21241 aacggtgtcc ccattttcag gtgcgaaagt ggagtacacg gcttcattgt cgccaatcat
    21301 gactttctcc aaattctccg caagtgtacc tccactttta ttcttgtcac ccaggatgga
    21361 aacttgtaag aaagcactcc ctttttggcc cttgtactca atctctgcat cacgaagctt
    21421 gtctgataat ggaattgttt gtaccacgta ttcttttttc gttctttctt gttcctcttt
    21481 catcgctttc tcatcatact tgtcacttgg aagatagatc gcttcacctg ctacaaactt
    21541 gaaatcggtc cccatctctg tcggcacctt gaacagatgg ccaacctttt gttccatgtc
    21601 cttccacgtt gtataggtaa aaggcttgga tcgtacatct acgaacggag tactgtttgg
    21661 atttgattcc aactgaagtt ttgtcagctg ccaataaatg gcaaccgctt cgccaggttt
    21721 taatccattg acgatttgtt cccccgtatc caactgttta aaaatctctg catttcgatt
    21781 tttgatctga tcctttatgt cagggggtag ctgttgcatc ttttgttgct gttcttgcat
    21841 actcatttgt ttaagcttta gcactacttc gcccttctca tttttcaact gaatcatttc
    21901 catccccgcc catacggaag acgctcctac cagcatacct acggtgacta gcaagccaat
    21961 tttctttttc acgacttttt cctccttgtt ttccttggca cgaattgctg ccatgacttt
    22021 atgtttgaca tcgaccttcg ggactggctt cgctaccagc atatctcgca tgtgcttaaa
    22081 cggatttttg tccatcattc agcacccctc ccgtcgttgg cagataacgt ttgcactttt
    22141 ttaagatgcg ttcgaattgc ttacgcagcg ccgcaggctt tttgtccagc agctccgcga
    22201 tttcctcgta ctctctttcc tctagcacac gtaggaacat gagtgttcgt tcctcggcag
    22261 acagccgttt ccaaatacgc tcgagcggct ccccgaaata attgctgtcg atgctctcct
    22321 cgacataatt gcgtccatcc tgatcacggt tgtacaaaaa gggcaatacg cggcttaatt
    22381 tcctgcgctt tagcacattc gcacaatggt tgtaagcgat ccggtacagc catgcagaaa
    22441 atgacagtga gtacgtatac tggtcaagat gctcgtaggc acgaaacagg acttcctgga
    22501 cagcgtcttc cgcatcttgg cgatgaccga gcatgtgata gcagtatgta aagatcggtt
    22561 gttgatagtg atcgataatg agttcgtatt gctcaagaga acctgctttt atctcaatca
    22621 gcaggcgctc tatctctgtt ttttccactg tttgccctcc tctcactatg aataacaact
    22681 ggcatctttt gtttgtgaca cctattttag aaatttttgg ctatacaaat aaaaagggtg
    22741 ttccacccgt ttcgtacgaa aaatctcgta cttctggaag gaacaccctt attccatgct
    22801 tgcattcatt tgtttgttcg tactcttgtc gaatgtcttg attctttccc gggaaatcga
    22861 cagcacctgt cggcttcgct ttagaaatgc tctccgttgg cataatagct ttctttttga
    22921 taagcgacaa atgccatctc tacttctgga atgccaagag ataggacatg cttcgttaca
    22981 atctgggcaa actggtcacg aacttcttgc ccacgctcga accacgctac ttcgataaaa
    23041 ggaaacgact ccacgatttt cccgccaaaa acgcctgtcg tctgtaagca ttcgatcgtg
    23101 aaattgtccg tgccgcattg gcatagtgca gcaagctcca ctgcaagcgg ttcgctaatc
    23161 gttgccattt gttcggcttg aatgcctcga acgataagat gtggcatgat gatccctcct
    23221 gaaaagtcca tatgctctat cttaccgttc agcaggcaaa aagagtagaa aaaactaggt
    23281 cagagctggg gcgtttccgt gctttcctac tgcctcttgc acccgcgctt ctttgttccc
    23341 ttgctgcaat tgatacatct gatagtacct gccttgcttc tccatcaagt cctcatgctt
    23401 tccacgctct acaattctgc ctcgatccag tacgagaatt tgatctgcat ttttgatcgt
    23461 agacaggcga tgagcaatga tgaaggtcgt tctccctttt ttcaacacct caagtgcatt
    23521 ttgaataatg ccctctgttt ccgtgtcgat gctg
//
