LOCUS NZ_VFNO01000005 60513 bp DNA linear CON 16-AUG-2024 DEFINITION Brevibacillus sp. AG162 Ga0222362_105, whole genome shotgun sequence. ACCESSION NZ_VFNO01000005 VERSION NZ_VFNO01000005.1 KEYWORDS WGS; RefSeq. SOURCE Brevibacillus sp. AG162 ORGANISM Brevibacillus sp. AG162 Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus. REFERENCE 1 (bases 1 to 518238) AUTHORS Venturi,V. TITLE Genome sequencing of rice bacterial endophytes JOURNAL Unpublished REFERENCE 2 (bases 1 to 518238) AUTHORS Venturi,V., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K., Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C., Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T. TITLE Direct Submission JOURNAL Submitted (14-JUN-2019) Prokaryotic Super Group, DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA COMMENT ##Genome-Assembly-Data-START## Assembly Method :: SPAdes v. 3.12.0 Genome Representation :: Full Expected Final Version :: No Genome Coverage :: 236.0x Sequencing Technology :: Illumina HiSeq ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_006715575.1-RS_2024_08_16 Annotation Date :: 08/16/2024 02:19:50 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.8 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 6,054 CDSs (total) :: 5,923 Genes (coding) :: 5,868 CDSs (with protein) :: 5,868 Genes (RNA) :: 131 rRNAs :: 1, 6, 5 (5S, 16S, 23S) complete rRNAs :: 1 (5S) partial rRNAs :: 6, 5 (16S, 23S) tRNAs :: 111 ncRNAs :: 8 Pseudo Genes (total) :: 55 CDSs (without protein) :: 55 Pseudo Genes (ambiguous residues) :: 0 of 55 Pseudo Genes (frameshifted) :: 25 of 55 Pseudo Genes (incomplete) :: 38 of 55 Pseudo Genes (internal stop) :: 3 of 55 Pseudo Genes (multiple problems) :: 11 of 55 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-12 15:50:39 NOTE :: This is a single region extracted from a larger record! Orig. start :: 321363 Orig. end :: 381876 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to VFNO01000005.1. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ FEATURES Location/Qualifiers region 1..60513 /candidate_cluster_numbers="1" /contig_edge="False" /product="NRP-metallophore" /product="NRPS" /region_number="2" /rules="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /rules="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /tool="antismash" cand_cluster 1..60513 /SMILES="NC(C(C)S)C(=O)NC(C(C)S)C(=O)NC(CS)C(=O)O" /candidate_cluster_number="1" /contig_edge="False" /detection_rules="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /detection_rules="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /kind="chemical_hybrid" /product="NRP-metallophore" /product="NRPS" /protoclusters="1" /protoclusters="2" /tool="antismash" protocluster 1..60513 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="False" /core_location="[20000:40513](-)" /cutoff="30000" /detection_rule="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /neighbourhood="20000" /product="NRP-metallophore" /protocluster_number="1" /tool="antismash" proto_core complement(20001..40513) /aStool="rule-based-clusters" /tool="antismash" /cutoff="30000" /detection_rule="(VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))" /neighbourhood="20000" /product="NRP-metallophore" /protocluster_number="1" protocluster 1..57523 /aStool="rule-based-clusters" /category="NRPS" /contig_edge="False" /core_location="[20000:37523](-)" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS" /protocluster_number="2" /tool="antismash" proto_core complement(20001..37523) /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)" /neighbourhood="20000" /product="NRPS" /protocluster_number="2" misc_feature 12..25 /note="TFBS match to PsrA, Oleic acid responsive regulator, confidence: medium, score: 22.17" /tool="antismash" gene complement(712..1815) /locus_tag="FB479_RS17785" /old_locus_tag="FB479_105310" CDS complement(712..1815) /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_process="GO:0009847 - spore germination [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007725063.1" /locus_tag="FB479_RS17785" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105310" /product="Ger(x)C family spore germination protein" /protein_id="WP_142066179.1" /transl_table=11 /translation="MKRIRLLAYYLLMAALLNGCGEEQVLEKLGLAVAVGYDQIGDGRL LGTTVFYQIDPEARQLVTVIAGTANTSKGLKITHNRESSKKIVGGQIRVAVYQDELARK GILPLVENLSRDASIGSNVYLTVAKGRASDILTHRYPETSNIGIYLYQAIRQNVNGENM ISSKLHEFMKDYYAVGKDPVMPYIERVKNELHIDKIALFRDERLAGEISTREGFFLKIL RERYNKGELEINLTVDNKRFFTVIEHISSKKQIKLLDLDKPRFSVKVKMTAQIQEMAEQ IDLSKPEELHKVQKAIQLAVKKETEGLLEKLRKHQVDPVGFGEIYNIARQKSGKKKLNR DECREVMKRAQFDVDVQVKILRTGVIG" gene complement(1812..2909) /locus_tag="FB479_RS17790" /old_locus_tag="FB479_105311" CDS complement(1812..2909) /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_process="GO:0009847 - spore germination [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007725065.1" /locus_tag="FB479_RS17790" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105311" /product="GerAB/ArcD/ProY family transporter" /protein_id="WP_255438438.1" /transl_table=11 /translation="MSTIRRHSHMFISVSLAMFIVHGNQVGIGIAGVQRFIYDRVQQDA WIAVIIAGLMTHVTAWVMLKILRKYKNLDLYDIHQMVFGKWPAKVLNLIFIIYIMGSAL TILRGYIEIIQSWMFPEVPSWLLNASLLCLAIYGVTGGIRVLAGISFFSVGLTICQLLL MIYPAQYADFNLLQPVFHHDLVELLDGARKMSFSIIGFEIILFIYPFVKEKQLLSRYVH GGLLMTTLLYVVVMLVTLLYFQGEQLKHLIWATLMMMKIVEFPFLERFEFVSISLWMLI MLDNLLLNLWVAMRGVHHIGGFKERKALIGIVIVMFFASNFLETRQSINWITDIFGAVG FYIIFVYPLILYIVILLFRKGTVRT" gene complement(2927..4402) /locus_tag="FB479_RS17795" /old_locus_tag="FB479_105312" CDS complement(2927..4402) /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_process="GO:0009847 - spore germination [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892664.1" /locus_tag="FB479_RS17795" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105312" /product="spore germination protein" /protein_id="WP_142066180.1" /transl_table=11 /translation="MTTNMIPDSIQETQEILWQQMRNPRLSFRSLSCGNNSLLLAYLPY LIDMVILQQVLLPFLERLPDEKIAPDTLLGNLPVAKVRKTIDYRQVSDYLVRGWIYLQI EGEDCGLLLFVANIPSRSLGEAQVEVQIFGPQVAFTEAFETNFGILQSYLTTDMLSNVS ITIGRRSKTNVEVCYMEELADPENVQTVVQRVRELDVDGLIDSGKLVQLIDDNTFSIFP QLIMTERPDYASEALLEGKVIVFVEGSPFAIMGPSTFVDFFKSNEDLYIRWQMASFIRL LRFLALFVSLFFTAIYVAALTFHYEMIPSALLVSLVKSRSKVPFPPLFEALLLEMIIEF LREAGARLPFKVGQTMGIVGGIVIGQAAVAAGFTSNILIMIVALSALASFTFPSYMMST AVRILRFPIILLAGIWGGFGIMLGASFLLIHILRQSSLGRPFFLPFFPFRLRDFKNSLI RVPFYNLGKRPALTRSPDNARLPDEAGKKRPIQ" misc_feature 4393..4407 /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 21.46" /tool="antismash" gene complement(4552..5607) /locus_tag="FB479_RS17800" /old_locus_tag="FB479_105313" CDS complement(4552..5607) /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1143: sugar-binding lipoprotein" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892665.1" /locus_tag="FB479_RS17800" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105313" /product="PotD/PotF family extracellular solute-binding protein" /protein_id="WP_106656966.1" /transl_table=11 /translation="MKRFKSLMIGALTAVLAVTAVGCSSSPEQEQQVLNIYSWADNFDP DVIKDFEQKFNVKVNYDVYGSNEEMLAKIQAGASGYDLIQPSDYMVGTMIQLGLLEELN KANIPNMGNIVSTFKTPPFDKENKYSLVYTWGITGIAYNKKYVKETPTSWNDLWNEAYK GRVIMLNDPREVMGMALIKNGFSNSTTNTEELEKSFADLKKVVPNVVAFDTDNIKQKMI AEEAWIGTVWSGDAAFIHAQNPDVEYVIPKEGATIWADTLAIPKGAKNKEMAEKFINYL MDPQVSVKNYESIGYSNPNEQAYPLHSEEYRSNKMVFVDKADIARAEWLVDVGETLQQY DRYWTEMKSGR" gene complement(5669..6466) /locus_tag="FB479_RS17805" /old_locus_tag="FB479_105314" CDS complement(5669..6466) /EC_number="7.-.-.-" /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_component="GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1069: putative ABC transporter permease protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892666.1" /locus_tag="FB479_RS17805" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105314" /product="ABC transporter permease" /protein_id="WP_142066181.1" /transl_table=11 /translation="MKTLRRNALSGYSWLMLVFLYLPILILVLYSFNDSRINATWTGFT WKWYVSLFENRQVMQALMNSLTIGIISSVIATVFGTAAALAVKHYSLRWSNIFNGLMYL PIVIPEIMMGLALLVLFSQVQMELGKVTLILAHVTFSMPYVMVIISGRLADMGKELEEA SQDLGATPWETLRYVTLPLIMPGIIAGFLMAFTLSLDDFIISFFVAGPNSTTLPLYIYG LVKRGVSPEVNALSTLLIVSTVLLVVVAEIFRRKDSKNNQSIF" gene complement(6463..7266) /locus_tag="FB479_RS17810" /old_locus_tag="FB479_105315" CDS complement(6463..7266) /EC_number="7.-.-.-" /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_component="GO:0055052 - ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1067: putative ABC transporter permease protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005545788.1" /locus_tag="FB479_RS17810" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105315" /product="ABC transporter permease" /protein_id="WP_047072025.1" /transl_table=11 /translation="MGALFVLPMLMIAILSFLKRGTYGQVVYEFTLNNYIRIFDPLYGQ IFGDTLVVAVLTTVFSILCGYPLAYYISRLEKSTQQIWLLLVMIPFWINFLVRSYAWVI ILRSQGVINTFLQSLGIISEPLPLLYNSGSVLLGMVYTLMPFMVLPIYVSLEQMDRRKL EAAYDLGATPWKAFWHVTLPMTKTGVVTGSILVFVSSIGMFVVPDVMGGAKSALIGNVI QNQFLSARDWPFGSALSIVLMLLSMLLILLYFRATKASETKEGSA" gene complement(7311..8297) /locus_tag="FB479_RS17815" /old_locus_tag="FB479_105316" CDS complement(7311..8297) /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1000: ABC transporter ATP-binding protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252041.1" /locus_tag="FB479_RS17815" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105316" /product="ABC transporter ATP-binding protein" /protein_id="WP_142066182.1" /transl_table=11 /translation="MKKIIHLDSIEKRFADTVVVPSFSLSIEEGEFLTLLGPSGCGKTT LLRMIAGFEQPTTGEIFLDEKPLKAVPPYQRDMNMVFQQYALFPHMTVEQNILFGLKMK KVNAAEQQKRLEEVLQYVQLTELRKRTPKQLSGGQQQRVAIARAIINNPRVLLLDEPLG ALDYQLRKSLQLELKNLQKNLGITFIYVTHDQEEAMAMSDRIAVMNKGRIEQIASPAEI YNSPQTLFVATFIGENNIFRENGTNAAVRPEKIKLYPIDSDKDKHKKLGTIADAVFLGN LRKVFIRLEGQDMTVMAHQYAGDGLDWQVGDQVAIGWAQTDEVILPC" misc_feature 8283..8296 /note="TFBS match to PerR, Peroxide regulator, confidence: weak, score: 20.73" /tool="antismash" misc_feature complement(8283..8298) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 21.16" /tool="antismash" gene complement(8489..9439) /locus_tag="FB479_RS17820" /old_locus_tag="FB479_105317" CDS complement(8489..9439) /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1166: transporter, EamA family" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252042.1" /locus_tag="FB479_RS17820" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105317" /product="DMT family transporter" /protein_id="WP_142066183.1" /transl_table=11 /translation="MKDQQKAIVAALLNAGITGLSFLFLKMALAVTNPVDTLAHRFTVA FIAASIPIVFGWIKLSIKPKDMLTIIPLAMLYPILFFTLQAFGLVYTTSSEAGIIQATV PIFTMIMAAFFLGESSTWLQKLSTLLSVGGVVYIFAMKGLGVSSGSGSSIGTILILLSA FSMAGYSVLARKMTKSFHYIDMTYMVALLGFIFFNGWSIIRHSAEGTLSTYFAPFASSA FIISIVFLGILSSLMTSFMTNFALSKMEASKLSVFNNLSTLVTIVAGVIFLQEQLAYYH LIGAVMIIIGVIGTNFLGAKSKNQNRTPQTKSTSV" gene 9577..10926 /locus_tag="FB479_RS17825" /old_locus_tag="FB479_105318" CDS 9577..10926 /GO_function="GO:0030170 - pyridoxal phosphate binding [Evidence IEA]" /NRPS_PKS="Domain: Aminotran_1_2 (97-371). E-value: 2.1e-29. Score: 94.7. Matches aSDomain: nrpspksdomains_FB479_RS17825_Aminotran_1_2.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1019: aminotransferase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252043.1" /locus_tag="FB479_RS17825" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105318" /product="PLP-dependent aminotransferase family protein" /protein_id="WP_142066184.1" /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-28, bitscore: 94.7, seeds: 48, tool: rule-based-clusters)" /transl_table=11 /translation="MHKYLQLQNELETLIESLSYRDGDRLPSIRELASRYQCSKSTVIR TLDELEKRHLIYSVDRSGYYVVKKQRKIQPADTSMIDFATSAPDPDLFPYIDFQHCINK AIETYKNDLFIYGTTQGLPSLIAVVAKLLGNHQVFTDPGNIFITSGVQQALSLLCSLPF PNGKETILIEQPSYHLFIESLQVRRYPVVGIKRTAQGIDLEELESIFRTGEIKFFYTMP RYHSPLGTTYSRKDKQRIVELAQQYDVYIVEDDYMADLEHDSKADPLFAYDRYSRTIYV KSYSKIIFPGLRLGVAVIPDALKDSFNQHKRLMDIDSSMLSQAALEIYLKSGMFERHKQ KIRSSYHRRSNLLMASLNHFTANEDHLFTFQPLAYPGIHTHIVLNDSIPVPAVISQLKK RSILVDSIDKNYLMGFPQENILKLNVSYAKEAVIEQGIHVLMDVLRRMHR" aSDomain 9868..10689 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17825_Aminotran_1_2.1" /evalue="2.10E-29" /label="FB479_RS17825_Aminotran_1_2.1" /locus_tag="FB479_RS17825" /protein_end="371" /protein_start="97" /score="94.7" /tool="antismash" /translation="FQHCINKAIETYKNDLFIYGTTQGLPSLIAVVAKLLGNHQVFTDP GNIFITSGVQQALSLLCSLPFPNGKETILIEQPSYHLFIESLQVRRYPVVGIKRTAQGI DLEELESIFRTGEIKFFYTMPRYHSPLGTTYSRKDKQRIVELAQQYDVYIVEDDYMADL EHDSKADPLFAYDRYSRTIYVKSYSKIIFPGLRLGVAVIPDALKDSFNQHKRLMDIDSS MLSQAALEIYLKSGMFERHKQKIRSSYHRRSNLLMASLNHFTANEDHLFTFQ" misc_feature 11265..11279 /note="TFBS match to CodY, Regulator of stationary phase and virulence in Gram-positive bacteria, confidence: medium, score: 21.29" /tool="antismash" gene 11265..11888 /locus_tag="FB479_RS17830" /old_locus_tag="FB479_105320" CDS 11265..11888 /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /codon_start=1 /gene_functions="other (smcogs) SMCOG1188: hypothetical protein" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892671.1" /locus_tag="FB479_RS17830" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105320" /product="YqaA family protein" /protein_id="WP_106656961.1" /transl_table=11 /translation="MFQNILDFLMEYGYMGMFIHSFADAVIFPVPAFFLQVPLSLVDPS QALWIATVGYIACLLGTPVGYFLGKVLGKSVLYKILKKEWIDSATEMFQKKGEVAIFIG SFTPIPFKVFTIMSGCLNFPLWKLIGYAAIGRAVKFYAVGFLFYFYGKMAENMVHDVSL YIFLTVVPLILVGLWVKKIVTKRRQLKMESTGVSNGINEKVMNK" gene complement(11944..14082) /locus_tag="FB479_RS17835" /old_locus_tag="FB479_105321" CDS complement(11944..14082) /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /codon_start=1 /gene_functions="other (smcogs) SMCOG1223: ATPase" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892672.1" /locus_tag="FB479_RS17835" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105321" /product="ATP-dependent Clp protease ATP-binding subunit" /protein_id="WP_142066185.1" /transl_table=11 /translation="MHCEICKQREATVTVHIRVQNQQQKYDLCQDCKTKLTNKMGVGMG FSPFSSFSGLDEFLQGFAQGRVNPGKSSSQPQPQAPERGGGILDDLGRNLNDAARAGLI DPVIGREQEIERVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALRITEGQVPTKLKNKQ VYILDVASLVAGTGIRGQFEEKMKQVIAELQKRKNVILFVDEIHLLVGAGSAEGSMDAG NILKPALARGELQLIGATTLKEYRVIEKDAALERRLQPVMVKEPTVEQAIEILKGLRPK YEAFHQVAYSDDVIRACVEYSHRYIQDRFLPDKAIDLMDEVGSRLNLRSSAVDTAELHE RLAQINQEKKEATEQEAYERAARLRDEEAGILEKLDQIEGKEQRVQVDVTDIQALIEQK TGIPVTKLQSDEQMKMKNLAAHLEAKVIGQSEAVTQVAKAIRRSRAGLKPKNRPIASFL FVGPTGVGKTELSKALAEELFGTRDSMIRLDMSEYMEKHSVSKLIGSPPGYVGHEEAGQ LTERVRRNPYSIILLDEIEKAHPDVMHMFLQILEDGRLTDSQGRTVNFKETVIIATSNA GVSERKISVGFGAQAPEPATVLDSLGAYFKPEFLNRFDSIISFAHLGKQDLVKIVDLLL QDVMGNLSEQGMEISVTDAAKEKLAELGYNPSFGARPLRRVIQQYVEDGIADLVMEEDN VTAMVIDVEDDVIRVKKG" gene complement(14201..15340) /locus_tag="FB479_RS17840" /old_locus_tag="FB479_105322" CDS complement(14201..15340) /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1184: major facilitator transporter" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892673.1" /locus_tag="FB479_RS17840" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105322" /product="MFS transporter" /protein_id="WP_142066186.1" /transl_table=11 /translation="MPSMIYLLAVAIFAMTTSEFMVAGMMNELADDFGVSIPSIGYFIT AYAGAMVIGGPILTATLLHIRRKQALLSLVAVFFIGQALGAMAWNYESMMLARILTGIA SSAAFGISVSISASLVPPHSRGKAASIVLAGLMIATVIGLPLTTVIAQYFGWRMSFWAV AVVVLLSGILIQWLLPSSAQKDQMNGKDELASFQNPHLWAAYATSMLIIGGTFAAFSYF TPILTDVTAFSAASIPYLLALYGIATVIGNIVIGRFADRFTMRILVTGLSMLVAALVLF AVGAENKWIAVLSIVLIGLTGVAMNPAMIARVMNTAGSGTMVNTVHTSFITLGVAIGSS LGGIGISSGYGLVSPLWVGACLAGIGLLSIVPYLQKSKV" gene complement(15405..16001) /locus_tag="FB479_RS17845" /old_locus_tag="FB479_105323" CDS complement(15405..16001) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1057: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006918184.1" /locus_tag="FB479_RS17845" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105323" /product="TetR/AcrR family transcriptional regulator" /protein_id="WP_142066187.1" /transl_table=11 /translation="MSKRGRPRDFDYTSIVDVAMKTFWSKGYNGCSTHDLCSDTGLGKG SLYNTFGSKQDLYLAVVEHYHETGIREQRALLESPGSVKERLQNFLAWALVEDFESTNP KGCLLINAGLERAKDEPKIEEIVSRHVELLKQAMEKVMEEGLQTGEIPQKRSAVDLASL FLSSYYGFRVLNTSTQNRTLAEQIMSGTMESIFGA" misc_feature 15965..15980 /note="TFBS match to CRP, Cyclic AMP receptor protein, confidence: medium, score: 17.19" /tool="antismash" gene complement(16154..16516) /locus_tag="FB479_RS17850" /old_locus_tag="FB479_105324" CDS complement(16154..16516) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017359114.1" /locus_tag="FB479_RS17850" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105324" /product="cupin domain-containing protein" /protein_id="WP_221629580.1" /transl_table=11 /translation="MMMKVNLAEKFSLFHEHWNPKIAGELNDSYVKLAKLKGEFVWHQH ENEDEMFLVVKGQLLIKFRDKDVWLNEGEFLIVPKGVEHMPVAEEEVHVLLLEPKTTLN TGDQVNEKTVTDLETI" gene complement(16527..17429) /gene="rbsK" /locus_tag="FB479_RS17855" /old_locus_tag="FB479_105325" CDS complement(16527..17429) /EC_number="2.7.1.15" /GO_function="GO:0004747 - ribokinase activity [Evidence IEA]" /GO_process="GO:0006014 - D-ribose metabolic process [Evidence IEA]" /codon_start=1 /gene="rbsK" /gene_functions="biosynthetic-additional (smcogs) SMCOG1276: PfkB domain protein" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007725107.1" /locus_tag="FB479_RS17855" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105325" /product="ribokinase" /protein_id="WP_142066189.1" /transl_table=11 /translation="MKIAVVGSINMDLVTHVHHLPKAGETITSHHFELIPGGKGANQAV AASRLGAHVSMIGMVGEDENGQVMVKGLTDAHVHIEGIKRSGTTGMAFINVSDDGENNI VLVPGANALVSTEHIADNLSILKDSDVVLLQLEIPMNVVEYTAKEAARLGKLVILNPAP ARELSSELLTHVHTLTPNETELSILTGMPVSTIDEVHAAAKKLLSGGPKRVIVTLGEKG ALLVTSDEATHIPAFRVEPVDTTAAGDSFTAAFAVGITQGMTETEAATFASKVAAIVVT RNGAQPSLPTFDEVQAYSF" gene 17598..18284 /gene="nfi" /locus_tag="FB479_RS17860" /old_locus_tag="FB479_105326" CDS 17598..18284 /EC_number="3.1.21.7" /GO_function="GO:0004519 - endonuclease activity [Evidence IEA]" /GO_process="GO:0006281 - DNA repair [Evidence IEA]" /codon_start=1 /gene="nfi" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252049.1" /locus_tag="FB479_RS17860" /note="cleaves DNA at apurinic or apyrimidinic sites; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105326" /product="deoxyribonuclease V" /protein_id="WP_142066190.1" /transl_table=11 /translation="MEPIIQHPWNIDEQEAINLQRQLAQQVKKEDQLADVRFIAGVDVA YHAESDLLVAGVVILDPTSLQVVESVVIQDTVEFPYIPGLFSFRELPPLVRAFQELKTT PQLVVCDGQGIAHPRRFGLASHLGVLFDIPTIGCGKTRLLGEYEEPAQERGVYSPLIDQ GEIIGGVLRTQPNIKPIFVSIGHGISLPTACAWITKLSPKYRLPETTRQADQLVNKVSA DLNSSR" gene complement(18281..18919) /locus_tag="FB479_RS17865" /old_locus_tag="FB479_105327" CDS complement(18281..18919) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007725111.1" /locus_tag="FB479_RS17865" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105327" /product="hypothetical protein" /protein_id="WP_106656954.1" /transl_table=11 /translation="MSAEKESRLCQRSKQIHNRTFVVTCKEFLVKQADFLLDVFADVED EIGPIKNGAKIQVGWTILLVFERDGYMEIVAPDYDSNPFSETTADLSVSLVVQMAQNNC LQTVRAEGESALFQDKMVVAKGAFEQEHVYLQRAEDVQKGDSGWYLGPVEGEVDSDQLA SYYVYELLKLRPSLLQALALPRGYIVVFQGDQIEAVLDEHDENVWPTLH" gene complement(19064..19825) /locus_tag="FB479_RS17870" /old_locus_tag="FB479_105328" CDS complement(19064..19825) /NRPS_PKS="Domain: Abhydrolase_1 (24-128). E-value: 2.4e-18. Score: 58.6. Matches aSDomain: nrpspksdomains_FB479_RS17870_Abhydrolase_1.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) PF00561" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1036: alpha/beta hydrolase fold protein" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007725114.1" /locus_tag="FB479_RS17870" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105328" /product="alpha/beta fold hydrolase" /protein_id="WP_142066191.1" /sec_met_domain="PF00561 (E-value: 1.7e-15, bitscore: 52.2, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-11, bitscore: 40.3, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MAIKRSKVSTSRGKIQYHWSGNGKPNIVLINGGSGPIEGWMKILP ELSETSSVFSYNRFGVSGSDKPQEPQDGLTIVETLREALKIVGFEPPFLLVGHSLGGLY ANLYARHYPNEVAGIVFLESSHPKDIGLDQYQGKVVKTINKILSMFDSLSPHKPFNEVH FVKRTVEQIHAIDYFPDIPVYVITGGKENRMMPEEVRKKRIEHQLELLSLSSNSKHILA ENSGHFPQFTEPKVVIDTIKDCIEQIQQKTL" aSDomain complement(19442..19753) /aSDomain="Abhydrolase_1" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17870_Abhydrolase_1.1" /evalue="2.40E-18" /label="FB479_RS17870_Abhydrolase_1.1" /locus_tag="FB479_RS17870" /protein_end="128" /protein_start="24" /score="58.6" /tool="antismash" /translation="PNIVLINGGSGPIEGWMKILPELSETSSVFSYNRFGVSGSDKPQE PQDGLTIVETLREALKIVGFEPPFLLVGHSLGGLYANLYARHYPNEVAGIVFLESSHPK " CDS_motif complement(19511..19552) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17870_0001" /evalue="1.20E-04" /label="NRPS-te1" /locus_tag="FB479_RS17870" /protein_end="105" /protein_start="91" /score="14.6" /tool="antismash" /translation="PFLLVGHSLGGLYA" gene complement(20001..24872) /locus_tag="FB479_RS17875" /old_locus_tag="FB479_105329" CDS complement(20001..24872) /NRPS_PKS="Domain: Heterocyclization (76-371). E-value: 3.2e-105. Score: 343.7. Matches aSDomain: nrpspksdomains_FB479_RS17875_Heterocyclization.1" /NRPS_PKS="Domain: AMP-binding (539-933). E-value: 1.3e-96. Score: 315.7. Matches aSDomain: nrpspksdomains_FB479_RS17875_AMP-binding.1" /NRPS_PKS="Domain: PCP (1210-1286). E-value: 2.8e-12. Score: 38.7. Matches aSDomain: nrpspksdomains_FB479_RS17875_PCP.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (rule-based-clusters) Thioesterase" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127: condensation domain-containing protein" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252051.1" /locus_tag="FB479_RS17875" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105329" /product="non-ribosomal peptide synthetase" /protein_id="WP_142066192.1" /sec_met_domain="Condensation (E-value: 5.8e-49, bitscore: 161.6, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 1.2e-106, bitscore: 351.6, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="PP-binding (E-value: 1e-09, bitscore: 33.6, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Thioesterase (E-value: 2.4e-20, bitscore: 68.5, seeds: 16, tool: rule-based-clusters)" /transl_table=11 /translation="MPQNLKTNSVELLMRLRRDGIFLWEENGSLRYRAPRGTLAADDLQ ALKEQKADILAILRAESQPVTVVPDPAARFMPFPLTDVQSAYLLGRYELFGYGGVACHI YIELDYPELDPKRAEDAWNLLIARHDMLRSTIDQNGQQRILEKVPHWTITYTDTSGMNE QEAGRRLDDIREAMGHRVYDTAKWPLFDIGLTKTSDRAVLHVSMEFLIADWASIWLLLG EFEALYKEPGKTLPALPITFRDYVFAERSLRETTTYGRDKAYWEQRIDALPQAPDLPMA KQQTQNGGARFRRRFIRLHNASWDAFKKRAQQRGLTPTAAVMTAFAAVIERWSRNRAFC LNLTLLNRQPLHERVHEIVGDFTSVNLLAVDWGLERSFQGRAKTIQKQLFEDLDHRLFS GVEVMRELARRRGREAALMPIVFTSAIGLVEPAEGGQLQGKIAGHGISQTPQVFIDCQA MDSQAGLQVNWDVREGVFPEHVVDDMFDTFAKLLQSLADSEQVWEGADEIALPDWQREE RQQVNATTAALPEYALHQPIVTQAMSTPDRPAVIDSEGQISYAELVKRAAAVAGKLKDL GCREQDRVAIVMDKGAHQVTAVLGTLFAGAVYVPIDPKQPEMRRQAMMEQADIRYALTV SASQLQWSDSIQTIAVDQVSPQHEPLILPDLNPDLPAYIIYTSGSTGQPKGVVISHRAA ANTIEDMLRRFAITESDRVLGLAQLSFDLSVYDIFATLSVGGAVVYPHPDRQTDPSHWS ELIVDHDITVWNSVPALMQMLVTYLDSTPTVKVDSLRLALLSGDWIPLTLPDRMQKYLP SAQIVSLGGATEASIWSNYHLYNGLEPDWNSIPYGRPLANQGFRVLDSQMRDCPVWVIG DLYITGAGLAEGYVGDQRLTEERFFSHPIDGERLYRTGDLGRYTPGGEIEFIGREDNQV KIRGHRIELGEIESALLKHPAVAAAGVVLDGASDEPVLLGIVESARKMDRDLEAERAEF AMLVDGIGEETGIEVNQGIGELLQRIARQHTPKSLRVLQVGTGNGALTEYVPQALEGYD AEYRSMDIVEGEYRAKGLAPNSFDVVLAAGDIESSDMSKLKELICPGGWLILTEWTEAS WISEWQKEEDALVFLLQKEGENHLLAHQVKLDRVRVSAAELEKFLSLHLPAYMLPAHLQ VVDALPLTGNGKIDRRELAKWRPASSFGQHAARDATEGAESDPLEAQLAHVWAEALGVP RIGRTQSFYEYGADSLIMAQVAGKLRDKLAEDPTHAAIPFDVLLRQMLNFPTVEALAGF LHMRNQEMQQSEEVALPTRRNKSSNAVLIPYGGDASGPLRVVFHAVLGTMDSFRPLIEQ LKAQQTGSIVGIAIDDSERYCALEPSELIETVADDYAACLIDILREGEQRPVQLIGYSL GGLIAIEVARRLGEQGVPILDLVLIDIPPILTEVNDDLLIEALFVPNLNITLEQADFGK VDEHDFARAILQLVEKYGDCIPQGSACTIGGDEGLDQVGEMFRKLSAFDRRERFTAYVH ALGKTSGEQMPVEMAEGLCKVFGQSFKAARYTPLPYMGDIRFLLACEPFQFLPSTSEET IAFWQDICIGELEVTEIAGNHYSCMAGENAVKLAELLAVPLGTK" CDS_motif complement(20631..20699) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0012" /evalue="4.90E-09" /label="NRPS-te1" /locus_tag="FB479_RS17875" /protein_end="1414" /protein_start="1391" /score="28.6" /tool="antismash" /translation="QRPVQLIGYSLGGLIAIEVARRL" aSDomain complement(21015..21242) /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17875_PCP.1" /evalue="2.80E-12" /label="FB479_RS17875_PCP.1" /locus_tag="FB479_RS17875" /protein_end="1286" /protein_start="1210" /score="38.7" /tool="antismash" /translation="EAQLAHVWAEALGVPRIGRTQSFYEYGADSLIMAQVAGKLRDKLA EDPTHAAIPFDVLLRQMLNFPTVEALAGFLH" aSModule complement(21015..24644) /complete /domains="nrpspksdomains_FB479_RS17875_Heterocyclization.1" /domains="nrpspksdomains_FB479_RS17875_AMP-binding.1" /domains="nrpspksdomains_FB479_RS17875_PCP.1" /locus_tags="FB479_RS17875" /monomer_pairings="Cys -> Cys" /tool="antismash" /type="nrps" CDS_motif complement(21426..21473) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0011" /evalue="7.50E-01" /label="NRPS-A_a8" /locus_tag="FB479_RS17875" /protein_end="1149" /protein_start="1133" /score="3.0" /tool="antismash" /translation="HQVKLDRVRVSAAELE" CDS_motif complement(22044..22109) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0010" /evalue="5.80E-12" /label="NRPS-A_a8" /locus_tag="FB479_RS17875" /protein_end="943" /protein_start="921" /score="37.5" /tool="antismash" /translation="FIGREDNQVKIRGHRIELGEIE" aSDomain complement(22074..23255) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17875_AMP-binding.1" /evalue="1.30E-96" /label="FB479_RS17875_AMP-binding.1" /locus_tag="FB479_RS17875" /protein_end="933" /protein_start="539" /score="315.7" /specificity="substrate consensus: Cys" /tool="antismash" /translation="QAMSTPDRPAVIDSEGQISYAELVKRAAAVAGKLKDLGCREQDRV AIVMDKGAHQVTAVLGTLFAGAVYVPIDPKQPEMRRQAMMEQADIRYALTVSASQLQWS DSIQTIAVDQVSPQHEPLILPDLNPDLPAYIIYTSGSTGQPKGVVISHRAAANTIEDML RRFAITESDRVLGLAQLSFDLSVYDIFATLSVGGAVVYPHPDRQTDPSHWSELIVDHDI TVWNSVPALMQMLVTYLDSTPTVKVDSLRLALLSGDWIPLTLPDRMQKYLPSAQIVSLG GATEASIWSNYHLYNGLEPDWNSIPYGRPLANQGFRVLDSQMRDCPVWVIGDLYITGAG LAEGYVGDQRLTEERFFSHPIDGERLYRTGDLGRYTPGGEIEFIGREDNQVKIR" CDS_motif complement(22188..22277) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0009" /evalue="5.30E-12" /label="NRPS-A_a6" /locus_tag="FB479_RS17875" /protein_end="895" /protein_start="865" /score="38.0" /tool="antismash" /translation="PVWVIGDLYITGAGLAEGYVGDQRLTEERF" CDS_motif complement(22800..22859) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0008" /evalue="8.50E-11" /label="NRPS-A_a3" /locus_tag="FB479_RS17875" /protein_end="691" /protein_start="671" /score="33.6" /tool="antismash" /translation="AYIIYTSGSTGQPKGVVISH" CDS_motif complement(23037..23078) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0007" /evalue="2.90E-03" /label="NRPS-A_a2" /locus_tag="FB479_RS17875" /protein_end="612" /protein_start="598" /score="11.3" /tool="antismash" /translation="LGTLFAGAVYVPID" CDS_motif complement(23487..23537) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0006" /evalue="8.40E-06" /label="Cy7" /locus_tag="FB479_RS17875" /protein_end="462" /protein_start="445" /score="18.7" /tool="antismash" /translation="ISQTPQVFIDCQAMDSQ" CDS_motif complement(23652..23699) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0005" /evalue="1.90E-07" /label="afterCy5" /locus_tag="FB479_RS17875" /protein_end="407" /protein_start="391" /score="23.3" /tool="antismash" /translation="DLDHRLFSGVEVMREL" CDS_motif complement(23760..23819) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0004" /evalue="5.40E-07" /label="Cy5" /locus_tag="FB479_RS17875" /protein_end="371" /protein_start="351" /score="21.9" /tool="antismash" /translation="HERVHEIVGDFTSVNLLAVD" aSDomain complement(23760..24644) /aSDomain="Heterocyclization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17875_Heterocyclization. 1" /evalue="3.20E-105" /label="FB479_RS17875_Heterocyclization.1" /locus_tag="FB479_RS17875" /protein_end="371" /protein_start="76" /score="343.7" /specificity="C activity: inactive" /specificity="Active site motif: EFLIADW" /tool="antismash" /translation="PFPLTDVQSAYLLGRYELFGYGGVACHIYIELDYPELDPKRAEDA WNLLIARHDMLRSTIDQNGQQRILEKVPHWTITYTDTSGMNEQEAGRRLDDIREAMGHR VYDTAKWPLFDIGLTKTSDRAVLHVSMEFLIADWASIWLLLGEFEALYKEPGKTLPALP ITFRDYVFAERSLRETTTYGRDKAYWEQRIDALPQAPDLPMAKQQTQNGGARFRRRFIR LHNASWDAFKKRAQQRGLTPTAAVMTAFAAVIERWSRNRAFCLNLTLLNRQPLHERVHE IVGDFTSVNLLAVD" CDS_motif complement(23820..23858) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0003" /evalue="2.50E-04" /label="afterCy4" /locus_tag="FB479_RS17875" /protein_end="351" /protein_start="338" /score="13.6" /tool="antismash" /translation="FCLNLTLLNRQPL" CDS_motif complement(23871..23930) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0002" /evalue="5.20E-08" /label="Cy4" /locus_tag="FB479_RS17875" /protein_end="334" /protein_start="314" /score="25.6" /tool="antismash" /translation="GLTPTAAVMTAFAAVIERWS" CDS_motif complement(24447..24500) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17875_0001" /evalue="3.70E-08" /label="Cy2" /locus_tag="FB479_RS17875" /protein_end="142" /protein_start="124" /score="25.6" /tool="antismash" /translation="LIARHDMLRSTIDQNGQQ" gene complement(24889..27216) /locus_tag="FB479_RS17880" /old_locus_tag="FB479_105330" CDS complement(24889..27216) /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /NRPS_PKS="Domain: cMT (543-654). E-value: 3.6e-39. Score: 125.8. Matches aSDomain: nrpspksdomains_FB479_RS17880_cMT.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) GFO_IDH_MocA" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252052.1" /locus_tag="FB479_RS17880" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105330" /product="bifunctional Gfo/Idh/MocA family oxidoreductase/class I SAM-dependent methyltransferase" /protein_id="WP_142066193.1" /sec_met_domain="GFO_IDH_MocA (E-value: 1.3e-21, bitscore: 72.4, seeds: 39, tool: rule-based-clusters)" /transl_table=11 /translation="MTKNRKLRTVVCGSRFGQFYLEAVKALPEQFELVGLLAKGSERSR QCAERNGIPLYTDVNQLPADIDLACVVLRSTVMGGNGTELAIQLLAKGIHVISEEPIHH KDLALCLKHAKQNGVHFMTGDLYVHLPAVRRFIACARTMLAVQPALYIEAACATQVSFP LMHILQEALPSIRPWKISHVIKDEGPFQVLIGQLGKIPITLRAHNEVDPDDPDNYLHLL HRVTIGVAGGSLSLTDTHGPVVWQPRLHVPDLPDIHGELTVSPPAHMLENSTHILGPQE TPTYRDILTKQWPQAIGRDLLIMRERIMGQVDKAAMETRAQQELLCSRQWQEWTQALGY PVLRSHGSHEPLSLASLEQAAWSIPDDEFHDTASPNDATLAENNDVFACTASAENELKG IDAVQVNTCIERLDAAAVASMLLALQSQGAWTAEQHSYTASDIFTAANVAERHHPVIKR WLHILTDRGFLKYAAGEYQCDIQMTREEVERRWELAKNAWNGKLGSPLVMDYLKDNADR LPQLMDDTQQAALLLFPEGRMHVANALYRDTLVARYLNKSVAEAVARIASTANSLRILE VGAGTGATSDVVVDHLKPSVSKGLNVEYVYTDVSHFFLSSARERYKACPWMKYQVVDID KDLFAQGLSEGSFDIVIAAGMLNNARDTDEVIQGLLKTLAPGGWMIITEPTREFVEMLI SQAFMMTPPVDDRKNTQSTFMTVQQWLDVFQRAGVQELAVLPEESHPLAPLGQKLFLIK NNIDAGVRQQLSQNENEMAKLI" aSDomain complement(25255..25587) /aSDomain="MT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17880_cMT.1" /domain_subtypes="cMT" /evalue="3.60E-39" /label="FB479_RS17880_cMT.1" /locus_tag="FB479_RS17880" /protein_end="654" /protein_start="543" /score="125.8" /tool="antismash" /translation="LYRDTLVARYLNKSVAEAVARIASTANSLRILEVGAGTGATSDVV VDHLKPSVSKGLNVEYVYTDVSHFFLSSARERYKACPWMKYQVVDIDKDLFAQGLSEGS FDIVIAA" gene complement(27226..28335) /locus_tag="FB479_RS17885" /old_locus_tag="FB479_105331" CDS complement(27226..28335) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003339897.1" /locus_tag="FB479_RS17885" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105331" /product="saccharopine dehydrogenase family protein" /protein_id="WP_255438449.1" /transl_table=11 /translation="MKKIGILGATGVVGQAAFQTILSRTNDPILLGGRNPEKLRELFTG TDGRVECQQVDVCNEEELHHFCGRVDLVINCAGPSKQIVDKVAVACLKHEVHYVDVSGD EHLYRQLLTRKQEIEEKGLLFIISAGVYPGLSEVFPAYVAENDLEEIDLLEVFFAGQGG FSLNAAYDIVCSIEEDTGWGMSYFKQGELKKIDGPFHRNYTLPHPAGKRDTYPVVTKEF GLMTKQHKIESAYFYNSYQSNAILNQFVMIKALQQYKTEEQKRASAKLLLEQFEAKKPG AKDFTMFHLHATGKRDGKKVRVFSTLLYPGDWNRISGIIAATVAHLIAEDQNRKTGCFF VAEGVSATGLIDALREQQVELMHSIMEMK" gene complement(28449..37523) /locus_tag="FB479_RS17890" /old_locus_tag="FB479_105332" CDS complement(28449..37523) /NRPS_PKS="Domain: PP-binding (24-80). E-value: 4.4e-10. Score: 31.7. Matches aSDomain: nrpspksdomains_FB479_RS17890_PP-binding.1" /NRPS_PKS="Domain: Heterocyclization (107-403). E-value: 9.3e-112. Score: 365.2. Matches aSDomain: nrpspksdomains_FB479_RS17890_Heterocyclization.1" /NRPS_PKS="Domain: AMP-binding (567-965). E-value: 2.9e-94. Score: 307.9. Matches aSDomain: nrpspksdomains_FB479_RS17890_AMP-binding.1" /NRPS_PKS="Domain: cMT (1219-1404). E-value: 2.3e-56. Score: 182.6. Matches aSDomain: nrpspksdomains_FB479_RS17890_cMT.1" /NRPS_PKS="Domain: PCP (1473-1540). E-value: 4.8e-25. Score: 79.6. Matches aSDomain: nrpspksdomains_FB479_RS17890_PCP.1" /NRPS_PKS="Domain: Heterocyclization (1561-1862). E-value: 2.2e-110. Score: 360.7. Matches aSDomain: nrpspksdomains_FB479_RS17890_Heterocyclization.2" /NRPS_PKS="Domain: AMP-binding (2029-2433). E-value: 4e-103. Score: 337.1. Matches aSDomain: nrpspksdomains_FB479_RS17890_AMP-binding.2" /NRPS_PKS="Domain: cMT (2678-2870). E-value: 6.7e-51. Score: 164.5. Matches aSDomain: nrpspksdomains_FB479_RS17890_cMT.2" /NRPS_PKS="Domain: PCP (2939-3008). E-value: 4.9e-22. Score: 69.9. Matches aSDomain: nrpspksdomains_FB479_RS17890_PCP.2" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: Condensation" /gene_functions="biosynthetic (rule-based-clusters) NRPS: AMP-binding" /gene_functions="biosynthetic (rule-based-clusters) NRPS: Condensation" /gene_functions="biosynthetic-additional (rule-based-clusters) PP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1127: condensation domain-containing protein" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007716334.1" /locus_tag="FB479_RS17890" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105332" /product="non-ribosomal peptide synthetase" /protein_id="WP_142066195.1" /sec_met_domain="PP-binding (E-value: 7.2e-14, bitscore: 46.9, seeds: 164, tool: rule-based-clusters)" /sec_met_domain="Condensation (E-value: 4.8e-54, bitscore: 178.2, seeds: 42, tool: rule-based-clusters)" /sec_met_domain="AMP-binding (E-value: 1.7e-110, bitscore: 364.3, seeds: 400, tool: rule-based-clusters)" /transl_table=11 /translation="MSKMLNDSLTASPAASLSYEEMKRQIQALLPAPVAFSDDQNLIEL GLDSLQMMRMVNKWRKEGAKVTFAELIGAPTLRDWQALLQKSSPSLPHVDERKTDVEVE VNVPFPLTDVQYAYWIGRQDDQPLGGVGCHAYLEIDGAGVEPDRLETAWGKLLMHHPML RARFLADGQQEVMSAPRSTAVPVHDLRSFSEDELVRELDGIRERLSHRRLAVEAGEVAG LELSLLPEGRTRIHFDLDLLVADVQSLHIVLRDLAAAYARDSKPLAPTNWSFAHYLGQE AERRAQDRQEAARYWQERLSTLPGAPGLPLKEKPEMIKSPVFTRRTHFMKPAEWALLQK RSAAQRVTPAMVLLTAYAEVLDRWSTHSQFLINIPLFDRQTGDAGIEDVVADFTNLLLL AVDMREPSSFLARVQSVQSQFHQDVAHAAYSGVQLQRDMARVRQGERDFAPVVFACNLG TPLINDECRDTLGKLSYMISQTPQVWLDFQSYEMDGGLLLAWDAVDQLFPDGMLDQMFG AFCQLMDSLVTEDNDWQAPSVLLPDLEQKRNHQAVDDSQPQSSHCLHSAFFAYAKENPH ELALIDSHASTTFSYGELATYALQIAAYLQKQGVEAGDPVAISLPRGIDQVAAVLGIVA RGACYVPIGMGQPSTRRERIHQKAEIRYVLTDTEQAQTLEWPKDAVVLSVTDALNVSPL AEPVPISFDSLAYIIFTSGSTGEPKGVEINHSGAWNTIAEINRRYGIGQTDRILAVSSL DFDLSVYDLFGLLSVGGSIVLIGEEVRRDAAYWARLVDQHQVTLWNSVPVLLDMLLIAA ESGPYESLPLRLTMLSGDWIGLDLPQRLNQLAPNSQLVAMGGATEASIWSNFFDVTLPL PAHWTSIPYGRPLANQAYRVVDAHGRDCPDWVEGELWIGGAGVAVGYRGDPALTAERFV NWNGSRWYRTGDLGRYWPDGTIEFLGRKDFQVKIRGHRIELGEIESAMKQHPGIRDAVV TAVGDPRENRQLVGYVVPERESESALFDRLEADPKKSEELWADVVDTGRVQTLSEHFAS IRPEDFTSIWAYMEKLAVRFIYRTLEMAGVNFEQNANYSLDDLMQNCGIQERYRGLVRQ WLQTLEDEGFVRKDKSDVYSITQASLTEWLEKPHVSHVLPAWEHQAQALLRYLEKVNDE SVALLRGELDPLAHFFSEESNLTPNDLMQTLPGAKHRDSAALALVERLIHRLGKRSESE PIRVLEIGARSLALTESLLAVLPADATHFTCTDTSTFFTNAAKTRFREYPFVHYQLLDI NQSPRSQGFEAHQFDVVIASDSLHRAKNIGMALSYVQSLLSPGGMLILLEMTRNSRLQQ ISTAFLEDGFTHFEDERRNEQRPLLSVEAWQQALQQQAFAQVAAFPEQNDFGQHVLVAQ APLQAKRFNAAKLSGFLSQKLPDYMVPTAFLLLNELPLSANGKVDRQALPTPDSLMKAK TEKAYTAPTTPIETALAAIWCQLFEVERVGVTDNYFELGGDSLLATRLSAMVRSKLAVE LSLGRIFEKPTIAGLAQHVEMLLEEKGEASGLPAIVLAPQDRHQPFPLTDIQQAYWVGR SGVYALGHVSTHCYFEIEGQYLDLERINRAWQRLIDHHEMMRAVILPDGWRQQILEQVP AYRIEVMDLRNQSAEEAESELQAIREEMSHQVLSTDVWPLFDVRASRFGDERVRLHISF DNLIFDGWSMFHLLSEWTRLYHEPDAPLPPLDLSFRDYVLAQEALKSTELYQRDLDYWM DRLPDLPPAPQLPLAKNPDTITEQRFHRLEARINRQAWQRLKKRTAEVGLTPSGILLTA YAETLGAWSKSSRFTINLTQFNRLPLHAQVGEIVGDFTTLTLLAVELSAGETILERGRN LQQQLWRDLDHPYVGGVQVQRELAKQTGEHSGVAMPIVFTSALGVEQWSGSDSDGKWLG KLVYNITQTPQVWLDHQVVEQDGELLLIWDAVEGLFPEGLLADMFTAYCELLHRLTEED AVWQEAAPSLIAVPRLEERIAANDTAAPLSTETLVGLFDKQAACQTDQPAVISTQRTLT YGELADTADQIARWLRLKGVEPNTLVAVVMEKGWEQVAATLGIMKSGTAYLPIDPQHPE ERRSQLLHDGQVQFVLTQSWLDERLGWPADVERLIVDQMTARDEGSTVNAVTPVAGQPE DLAYVIYTSGSTGLPKGVMIDHRGAVNTIEDINQRFAVGPQDRVLALSNLNFDLSVYDI FGMLAAGGTIVMPDADKAKDPAHWLEWLEAEQVTVWNTVPALMQMLIEYAVGRNLHLPQ SLRLVLLSGDWIPLDLPDKIKSFFPHVQVIGLGGATEASIWSNLFAIEEIDPSWKSIPY GRPMVNQRYHVLNESMGDCPVWVPGQLFISGIGLAKGYWRDENKTNEKFITHPRTGERL YRTGDLGRYLPDGKLEFLGREDFQVKIRGHRIELGEIETALKRHDGIKDVVVAVPDDGA DEKRLVGYVVLDREKDSALFETELADPAASAARWQTINSIGHTQADTIPASVDVEAVTQ FLMEADRVSTAYLCRTLEHMGMFAQVGESTTIAELMHRFQIHPRYQTLLAHWLEVLVEE GLLEKRAAGKYVSLRSLREGVPDDVLSASSLRTEAARELEAVFRRDYPLFIGLLTGELD PLELFLADDAFLTPAGLSRFDLTREFYSSLAGAVFGSIVSHHPSDKTLRVLELGTRAGS LTQTLVSTLPAERSRYLYVDESSFFTDRAKKEWGEQAPLEYGQLDMNVSPLAQGYDPHS FDVIVADNTLHRSRDIGKTLAYLKGLLAPGGLLFLVESTRNSRLLLTTVGFFEDGFSHL EDERKANHLPLLAVEQWRTGLEAQGFTNVLAIPDKAQVAEAFERHLIVAQAPEAVRLFQ PEKLSEALRNSLPDYMVPSEYVLLDELPLSANGKVDRKAITKLGKRKASMPKKTHVAPS NELEVKLAKVWEEVLGVAEIGIHDSFFSRGGDSLRAIQCLNLLRERYQIDLSLQSLFEA STICTLAELIKTSTQATEDLAADFDEGTI" aSDomain complement(28500..28706) /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_PCP.2" /evalue="4.90E-22" /label="FB479_RS17890_PCP.2" /locus_tag="FB479_RS17890" /protein_end="3008" /protein_start="2939" /score="69.9" /tool="antismash" /translation="EVKLAKVWEEVLGVAEIGIHDSFFSRGGDSLRAIQCLNLLRERYQ IDLSLQSLFEASTICTLAELIKTS" aSModule complement(28500..32840) /complete /domains="nrpspksdomains_FB479_RS17890_Heterocyclization.2" /domains="nrpspksdomains_FB479_RS17890_AMP-binding.2" /domains="nrpspksdomains_FB479_RS17890_cMT.2" /domains="nrpspksdomains_FB479_RS17890_PCP.2" /locus_tags="FB479_RS17890" /monomer_pairings="Cys -> Me-Cys" /tool="antismash" /type="nrps" aSDomain complement(28914..29489) /aSDomain="MT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_cMT.2" /domain_subtypes="cMT" /evalue="6.70E-51" /label="FB479_RS17890_cMT.2" /locus_tag="FB479_RS17890" /protein_end="2870" /protein_start="2678" /score="164.5" /tool="antismash" /translation="IVSHHPSDKTLRVLELGTRAGSLTQTLVSTLPAERSRYLYVDESS FFTDRAKKEWGEQAPLEYGQLDMNVSPLAQGYDPHSFDVIVADNTLHRSRDIGKTLAYL KGLLAPGGLLFLVESTRNSRLLLTTVGFFEDGFSHLEDERKANHLPLLAVEQWRTGLEA QGFTNVLAIPDKAQVAEAFERHLIVAQAP" CDS_motif complement(29226..29249) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0029" /evalue="4.60E+01" /label="Cy3" /locus_tag="FB479_RS17890" /protein_end="2766" /protein_start="2758" /score="-1.8" /tool="antismash" /translation="SFDVIVAD" CDS_motif complement(30195..30260) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0028" /evalue="7.60E-12" /label="NRPS-A_a8" /locus_tag="FB479_RS17890" /protein_end="2443" /protein_start="2421" /score="37.1" /tool="antismash" /translation="FLGREDFQVKIRGHRIELGEIE" aSDomain complement(30225..31436) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_AMP-binding.2" /evalue="4.00E-103" /label="FB479_RS17890_AMP-binding.2" /locus_tag="FB479_RS17890" /protein_end="2433" /protein_start="2029" /score="337.1" /specificity="substrate consensus: Cys" /tool="antismash" /translation="FDKQAACQTDQPAVISTQRTLTYGELADTADQIARWLRLKGVEPN TLVAVVMEKGWEQVAATLGIMKSGTAYLPIDPQHPEERRSQLLHDGQVQFVLTQSWLDE RLGWPADVERLIVDQMTARDEGSTVNAVTPVAGQPEDLAYVIYTSGSTGLPKGVMIDHR GAVNTIEDINQRFAVGPQDRVLALSNLNFDLSVYDIFGMLAAGGTIVMPDADKAKDPAH WLEWLEAEQVTVWNTVPALMQMLIEYAVGRNLHLPQSLRLVLLSGDWIPLDLPDKIKSF FPHVQVIGLGGATEASIWSNLFAIEEIDPSWKSIPYGRPMVNQRYHVLNESMGDCPVWV PGQLFISGIGLAKGYWRDENKTNEKFITHPRTGERLYRTGDLGRYLPDGKLEFLGREDF QVKIR" CDS_motif complement(30339..30428) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0027" /evalue="2.60E-10" /label="NRPS-A_a6" /locus_tag="FB479_RS17890" /protein_end="2395" /protein_start="2365" /score="32.6" /tool="antismash" /translation="PVWVPGQLFISGIGLAKGYWRDENKTNEKF" CDS_motif complement(30951..31010) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0026" /evalue="4.30E-10" /label="NRPS-A_a3" /locus_tag="FB479_RS17890" /protein_end="2191" /protein_start="2171" /score="31.5" /tool="antismash" /translation="AYVIYTSGSTGLPKGVMIDH" CDS_motif complement(31209..31250) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0025" /evalue="2.20E-03" /label="NRPS-A_a2" /locus_tag="FB479_RS17890" /protein_end="2105" /protein_start="2091" /score="11.6" /tool="antismash" /translation="LGIMKSGTAYLPID" CDS_motif complement(31590..31619) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0024" /evalue="4.80E-01" /label="afterCy7" /locus_tag="FB479_RS17890" /protein_end="1978" /protein_start="1968" /score="4.4" /tool="antismash" /translation="FPEGLLADMF" CDS_motif complement(31635..31709) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0023" /evalue="4.20E-07" /label="Cy7" /locus_tag="FB479_RS17890" /protein_end="1963" /protein_start="1938" /score="22.7" /tool="antismash" /translation="ITQTPQVWLDHQVVEQDGELLLIWD" CDS_motif complement(31770..31799) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0022" /evalue="1.30E-02" /label="Cy6" /locus_tag="FB479_RS17890" /protein_end="1918" /protein_start="1908" /score="8.5" /tool="antismash" /translation="MPIVFTSALG" CDS_motif complement(31833..31880) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0021" /evalue="1.50E-04" /label="afterCy5" /locus_tag="FB479_RS17890" /protein_end="1897" /protein_start="1881" /score="14.6" /tool="antismash" /translation="DLDHPYVGGVQVQREL" aSDomain complement(31938..32840) /aSDomain="Heterocyclization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_Heterocyclization. 2" /evalue="2.20E-110" /label="FB479_RS17890_Heterocyclization.2" /locus_tag="FB479_RS17890" /protein_end="1862" /protein_start="1561" /score="360.7" /specificity="C activity: active" /specificity="Active site motif: DNLIFDG" /tool="antismash" /translation="RHQPFPLTDIQQAYWVGRSGVYALGHVSTHCYFEIEGQYLDLERI NRAWQRLIDHHEMMRAVILPDGWRQQILEQVPAYRIEVMDLRNQSAEEAESELQAIREE MSHQVLSTDVWPLFDVRASRFGDERVRLHISFDNLIFDGWSMFHLLSEWTRLYHEPDAP LPPLDLSFRDYVLAQEALKSTELYQRDLDYWMDRLPDLPPAPQLPLAKNPDTITEQRFH RLEARINRQAWQRLKKRTAEVGLTPSGILLTAYAETLGAWSKSSRFTINLTQFNRLPLH AQVGEIVGDFTTLTLLAVEL" CDS_motif complement(31941..32000) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0020" /evalue="1.90E-07" /label="Cy5" /locus_tag="FB479_RS17890" /protein_end="1861" /protein_start="1841" /score="23.3" /tool="antismash" /translation="HAQVGEIVGDFTTLTLLAVE" CDS_motif complement(32001..32039) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0019" /evalue="2.20E-03" /label="afterCy4" /locus_tag="FB479_RS17890" /protein_end="1841" /protein_start="1828" /score="10.9" /tool="antismash" /translation="FTINLTQFNRLPL" CDS_motif complement(32052..32111) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0018" /evalue="4.70E-09" /label="Cy4" /locus_tag="FB479_RS17890" /protein_end="1824" /protein_start="1804" /score="28.9" /tool="antismash" /translation="GLTPSGILLTAYAETLGAWS" CDS_motif complement(32406..32450) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0017" /evalue="8.30E-06" /label="Cy3" /locus_tag="FB479_RS17890" /protein_end="1706" /protein_start="1691" /score="18.9" /tool="antismash" /translation="RLHISFDNLIFDGWS" CDS_motif complement(32637..32687) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0016" /evalue="8.50E-07" /label="Cy2" /locus_tag="FB479_RS17890" /protein_end="1629" /protein_start="1612" /score="21.4" /tool="antismash" /translation="LIDHHEMMRAVILPDGW" CDS_motif complement(32787..32816) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0015" /evalue="4.60E-03" /label="Cy1" /locus_tag="FB479_RS17890" /protein_end="1579" /protein_start="1569" /score="9.8" /tool="antismash" /translation="DIQQAYWVGR" aSDomain complement(32904..33104) /aSDomain="PCP" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_PCP.1" /evalue="4.80E-25" /label="FB479_RS17890_PCP.1" /locus_tag="FB479_RS17890" /protein_end="1540" /protein_start="1473" /score="79.6" /tool="antismash" /translation="ETALAAIWCQLFEVERVGVTDNYFELGGDSLLATRLSAMVRSKLA VELSLGRIFEKPTIAGLAQHVE" aSModule complement(32904..37202) /complete /domains="nrpspksdomains_FB479_RS17890_Heterocyclization.1" /domains="nrpspksdomains_FB479_RS17890_AMP-binding.1" /domains="nrpspksdomains_FB479_RS17890_cMT.1" /domains="nrpspksdomains_FB479_RS17890_PCP.1" /locus_tags="FB479_RS17890" /monomer_pairings="Cys -> Me-Cys" /tool="antismash" /type="nrps" aSDomain complement(33312..33866) /aSDomain="MT" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_cMT.1" /domain_subtypes="cMT" /evalue="2.30E-56" /label="FB479_RS17890_cMT.1" /locus_tag="FB479_RS17890" /protein_end="1404" /protein_start="1219" /score="182.6" /tool="antismash" /translation="KRSESEPIRVLEIGARSLALTESLLAVLPADATHFTCTDTSTFFT NAAKTRFREYPFVHYQLLDINQSPRSQGFEAHQFDVVIASDSLHRAKNIGMALSYVQSL LSPGGMLILLEMTRNSRLQQISTAFLEDGFTHFEDERRNEQRPLLSVEAWQQALQQQAF AQVAAFPEQNDFGQHVLVAQAP" CDS_motif complement(34599..34664) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0014" /evalue="1.50E-12" /label="NRPS-A_a8" /locus_tag="FB479_RS17890" /protein_end="975" /protein_start="953" /score="39.4" /tool="antismash" /translation="FLGRKDFQVKIRGHRIELGEIE" aSDomain complement(34629..35822) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_AMP-binding.1" /evalue="2.90E-94" /label="FB479_RS17890_AMP-binding.1" /locus_tag="FB479_RS17890" /protein_end="965" /protein_start="567" /score="307.9" /specificity="substrate consensus: Cys" /tool="antismash" /translation="FAYAKENPHELALIDSHASTTFSYGELATYALQIAAYLQKQGVEA GDPVAISLPRGIDQVAAVLGIVARGACYVPIGMGQPSTRRERIHQKAEIRYVLTDTEQA QTLEWPKDAVVLSVTDALNVSPLAEPVPISFDSLAYIIFTSGSTGEPKGVEINHSGAWN TIAEINRRYGIGQTDRILAVSSLDFDLSVYDLFGLLSVGGSIVLIGEEVRRDAAYWARL VDQHQVTLWNSVPVLLDMLLIAAESGPYESLPLRLTMLSGDWIGLDLPQRLNQLAPNSQ LVAMGGATEASIWSNFFDVTLPLPAHWTSIPYGRPLANQAYRVVDAHGRDCPDWVEGEL WIGGAGVAVGYRGDPALTAERFVNWNGSRWYRTGDLGRYWPDGTIEFLGRKDFQVKIR" CDS_motif complement(34737..34826) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0013" /evalue="3.20E-14" /label="NRPS-A_a6" /locus_tag="FB479_RS17890" /protein_end="929" /protein_start="899" /score="45.0" /tool="antismash" /translation="PDWVEGELWIGGAGVAVGYRGDPALTAERF" CDS_motif complement(35349..35408) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0012" /evalue="4.80E-09" /label="NRPS-A_a3" /locus_tag="FB479_RS17890" /protein_end="725" /protein_start="705" /score="28.3" /tool="antismash" /translation="AYIIFTSGSTGEPKGVEINH" CDS_motif complement(35595..35633) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0011" /evalue="4.30E-01" /label="NRPS-A_a2" /locus_tag="FB479_RS17890" /protein_end="643" /protein_start="630" /score="4.7" /tool="antismash" /translation="LGIVARGACYVPI" CDS_motif complement(35976..36005) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0010" /evalue="4.90E-02" /label="afterCy7" /locus_tag="FB479_RS17890" /protein_end="516" /protein_start="506" /score="7.3" /tool="antismash" /translation="FPDGMLDQMF" CDS_motif complement(36021..36095) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0009" /evalue="1.70E-07" /label="Cy7" /locus_tag="FB479_RS17890" /protein_end="501" /protein_start="476" /score="23.9" /tool="antismash" /translation="ISQTPQVWLDFQSYEMDGGLLLAWD" CDS_motif complement(36150..36179) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0008" /evalue="1.10E+00" /label="Cy6" /locus_tag="FB479_RS17890" /protein_end="458" /protein_start="448" /score="3.1" /tool="antismash" /translation="APVVFACNLG" CDS_motif complement(36210..36257) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0007" /evalue="1.20E-03" /label="afterCy5" /locus_tag="FB479_RS17890" /protein_end="438" /protein_start="422" /score="11.8" /tool="antismash" /translation="DVAHAAYSGVQLQRDM" aSDomain complement(36315..37202) /aSDomain="Heterocyclization" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_Heterocyclization. 1" /evalue="9.30E-112" /label="FB479_RS17890_Heterocyclization.1" /locus_tag="FB479_RS17890" /protein_end="403" /protein_start="107" /score="365.2" /specificity="C activity: active" /specificity="Active site motif: DLLVADV" /tool="antismash" /translation="PFPLTDVQYAYWIGRQDDQPLGGVGCHAYLEIDGAGVEPDRLETA WGKLLMHHPMLRARFLADGQQEVMSAPRSTAVPVHDLRSFSEDELVRELDGIRERLSHR RLAVEAGEVAGLELSLLPEGRTRIHFDLDLLVADVQSLHIVLRDLAAAYARDSKPLAPT NWSFAHYLGQEAERRAQDRQEAARYWQERLSTLPGAPGLPLKEKPEMIKSPVFTRRTHF MKPAEWALLQKRSAAQRVTPAMVLLTAYAEVLDRWSTHSQFLINIPLFDRQTGDAGIED VVADFTNLLLLAVDM" CDS_motif complement(36318..36371) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0006" /evalue="3.20E-06" /label="Cy5" /locus_tag="FB479_RS17890" /protein_end="402" /protein_start="384" /score="19.5" /tool="antismash" /translation="GIEDVVADFTNLLLLAVD" CDS_motif complement(36384..36416) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0005" /evalue="4.50E-02" /label="afterCy4" /locus_tag="FB479_RS17890" /protein_end="380" /protein_start="369" /score="6.9" /tool="antismash" /translation="FLINIPLFDRQ" CDS_motif complement(36429..36488) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0004" /evalue="4.00E-10" /label="Cy4" /locus_tag="FB479_RS17890" /protein_end="365" /protein_start="345" /score="32.2" /tool="antismash" /translation="RVTPAMVLLTAYAEVLDRWS" CDS_motif complement(36780..36824) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0003" /evalue="1.20E-04" /label="Cy3" /locus_tag="FB479_RS17890" /protein_end="248" /protein_start="233" /score="15.3" /tool="antismash" /translation="RIHFDLDLLVADVQS" CDS_motif complement(37005..37052) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0002" /evalue="9.10E-07" /label="Cy2" /locus_tag="FB479_RS17890" /protein_end="173" /protein_start="157" /score="21.3" /tool="antismash" /translation="MHHPMLRARFLADGQQ" CDS_motif complement(37158..37187) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17890_0001" /evalue="2.80E-02" /label="Cy1" /locus_tag="FB479_RS17890" /protein_end="122" /protein_start="112" /score="7.6" /tool="antismash" /translation="DVQYAYWIGR" aSDomain complement(37284..37451) /aSDomain="PP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17890_PP-binding.1" /evalue="4.40E-10" /label="FB479_RS17890_PP-binding.1" /locus_tag="FB479_RS17890" /protein_end="80" /protein_start="24" /score="31.7" /tool="antismash" /translation="QIQALLPAPVAFSDDQNLIELGLDSLQMMRMVNKWRKEGAKVTFA ELIGAPTLRDW" gene complement(37553..40513) /locus_tag="FB479_RS17895" /old_locus_tag="FB479_105333" CDS complement(37553..40513) /EC_number="4.2.99.21" /GO_function="GO:0008909 - isochorismate synthase activity [Evidence IEA]" /GO_function="GO:0016833 - oxo-acid-lyase activity [Evidence IEA]" /NRPS_PKS="Domain: AMP-binding (30-435). E-value: 4e-85. Score: 277.8. Matches aSDomain: nrpspksdomains_FB479_RS17895_AMP-binding.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) NRP-metallophore: SalSyn" /gene_functions="biosynthetic-additional (rule-based-clusters) AMP-binding" /gene_functions="biosynthetic-additional (smcogs) SMCOG1002: AMP-dependent synthetase and ligase" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252055.1" /locus_tag="FB479_RS17895" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105333" /product="salicylate synthase" /protein_id="WP_142066196.1" /sec_met_domain="AMP-binding (E-value: 1.1e-90, bitscore: 298.9, seeds: 400, tool: rule-based-clusters)" /sec_met_domain="SalSyn (E-value: 5.3e-154, bitscore: 508.7, seeds: 14, tool: rule-based-clusters)" /transl_table=11 /translation="MRVSTEWYEQAAIAYEQRGFWEPLTIGQQLRKWAEQYQNKEALVE DEERLTYSELDSKVDALASGFYHMGIQKGDNVAVQLPNRISFVLTCFALFRIGAVPILV LPAHREAELDGIFALARPVAYILPTTFLGFDYTKMAEDLVKRHTSVKFVMTDGDSSIGR NLAEISGPPIELEAPSYKDTALLLLSGGTTGIPKLIPRTHTDYVYNAKATAARCQLTER SVYLAVLPIAHNFPLCCPGILGTLSVGGKIVLCKTTSCDEAFPLIEKERVTITGLVPSI VQVWQEVLEWDTESDLSSLEVLQVGGSMLDDNLASRITREWKCKLQQVFGMAEGLICCT SLDDPESIITSCQGRPISEGDEVRIVDEHGNDVAPGEYGELIVRGPYTIRGYYRAEEQN RESFTPDGFYRSGDKARITPEGNIQIGGRIKEQINRAGEKIMPAEVETYLRMHPAIKDA ALITLPDPVLGEKSCAFLITDDETISLADVHAFFQEKGVARYKMPDQIERIDYWPLTSV GKVNKAKLKELALAPKSETKPAEIAYLEETFAFAGDAHMAAALIAERSGYENYLLYENG DELSLGMGIHALLYVDGAQTTLTYRNETLRFDNNELSETLEKAMAQVPIQNWRAYGTVH FGMARYYQGLPLMPEEGCLLKLFVPEVELRFNKGTVLLRALREEKRSEFSQLLRELSMN THAEQQLTQRVDKPKLSVPQTDTYDAEAYMQNVAEAVREIQEHKYHKVILSRKIPLDHE LDLVASYIAGRRVNTPARSFLVSLDGLGAAGFSPETVVEVDSDGWVSTFPLAGTRAKGS SEEEASRLKEELLNDPKEIAEHAVSVKLAFEELKSVCDSTSIVLNDFMSVASRGTVQHI ASRLKGKLKQECNSWDAFRALFPAVTASGIPKRESIEAIGRLENVPRGLYSGCVMTFDS DGAMDAALVLRTIYQKDNQAWLHAGAGVVEMSLPSRELEETREKLSSFSRQLIGKE" aSDomain complement(39209..40423) /aSDomain="AMP-binding" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17895_AMP-binding.1" /evalue="4.00E-85" /label="FB479_RS17895_AMP-binding.1" /locus_tag="FB479_RS17895" /protein_end="435" /protein_start="30" /score="277.8" /specificity="substrate consensus: diOH-Bz" /tool="antismash" /translation="RKWAEQYQNKEALVEDEERLTYSELDSKVDALASGFYHMGIQKGD NVAVQLPNRISFVLTCFALFRIGAVPILVLPAHREAELDGIFALARPVAYILPTTFLGF DYTKMAEDLVKRHTSVKFVMTDGDSSIGRNLAEISGPPIELEAPSYKDTALLLLSGGTT GIPKLIPRTHTDYVYNAKATAARCQLTERSVYLAVLPIAHNFPLCCPGILGTLSVGGKI VLCKTTSCDEAFPLIEKERVTITGLVPSIVQVWQEVLEWDTESDLSSLEVLQVGGSMLD DNLASRITREWKCKLQQVFGMAEGLICCTSLDDPESIITSCQGRPISEGDEVRIVDEHG NDVAPGEYGELIVRGPYTIRGYYRAEEQNRESFTPDGFYRSGDKARITPEGNIQIGGRI KEQINR" CDS_motif complement(39305..39391) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17895_0001" /evalue="4.00E-04" /label="NRPS-A_a6" /locus_tag="FB479_RS17895" /protein_end="403" /protein_start="374" /score="12.8" /tool="antismash" /translation="PGEYGELIVRGPYTIRGYYRAEEQNRESF" misc_feature 40623..40638 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 22.12" /tool="antismash" misc_feature complement(40623..40641) /note="TFBS match to FuR_variant_2, Ferric Uptake Regulator, confidence: weak, score: 25.85" /tool="antismash" misc_feature complement(40626..40641) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: medium, score: 25.83" /tool="antismash" misc_feature 40631..40645 /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 21.06" /tool="antismash" gene complement(40827..41495) /locus_tag="FB479_RS17900" /old_locus_tag="FB479_105334" CDS complement(40827..41495) /NRPS_PKS="Domain: ACPS (113-174). E-value: 9.3e-11. Score: 33.6. Matches aSDomain: nrpspksdomains_FB479_RS17900_ACPS.1" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1012: 4'-phosphopantetheinyl transferase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252056.1" /locus_tag="FB479_RS17900" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105334" /product="4'-phosphopantetheinyl transferase superfamily protein" /protein_id="WP_255438439.1" /transl_table=11 /translation="MLLAKGEVHIWLTFVQAWEHRMQELEGDLSAEELDKRARFHFHAD RERYVVAHGLLRKMTGLYQGISPRAVQWECNSNGKPLLCGADSDSEALFFNLSHSHELV AVAFSRDRLLGVDVEHLRHIPEMEQLMSYFHPVERERILRLPFDERQQAFFDCWTRKEA FVKATGEGLIRPLDSFFMEKQDGSFTVNGDGIRSGEWKVYGFTPARGYAGAVAIGIGRP " aSDomain complement(40974..41156) /aSDomain="ACPS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17900_ACPS.1" /evalue="9.30E-11" /label="FB479_RS17900_ACPS.1" /locus_tag="FB479_RS17900" /protein_end="174" /protein_start="113" /score="33.6" /tool="antismash" /translation="LGVDVEHLRHIPEMEQLMSYFHPVERERILRLPFDERQQAFFDCW TRKEAFVKATGEGLIR" gene complement(41575..42348) /locus_tag="FB479_RS17905" /old_locus_tag="FB479_105335" CDS complement(41575..42348) /NRPS_PKS="Domain: Thioesterase (19-240). E-value: 9.6e-55. Score: 178.4. Matches aSDomain: nrpspksdomains_FB479_RS17905_Thioesterase.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Thioesterase" /gene_functions="biosynthetic-additional (rule-based-clusters) Abhydrolase_6" /gene_functions="biosynthetic-additional (smcogs) SMCOG1004: thioesterase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018671916.1" /locus_tag="FB479_RS17905" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105335" /product="thioesterase II family protein" /protein_id="WP_244937511.1" /sec_met_domain="Thioesterase (E-value: 1.8e-53, bitscore: 176.8, seeds: 16, tool: rule-based-clusters)" /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-10, bitscore: 36.8, seeds: 455, tool: rule-based-clusters)" /transl_table=11 /translation="MDTIAKSWLLTQPQAKDSVRLFCFPYAGGGASIYRGWAQAFPSDV GVYPVQLPGRENRIAERAYSDMGELVEELAQVIHPYLDRPFLFFGHSMGTRIAFELARA VQSKWGRLPLGLIVSGGRAPHFPEPKPIYHLPDDEFVAALRRFSGTPEAILQSKELMQL FMPLLRGDFTLDETYVYAEEPPLDCPIAAYCGTEDQEATQEEMEAWASHTSAGFTFEMV DGGHFFLTTNKEVLLQSVTKMIGQYRSAVAGKGER" aSDomain complement(41629..42291) /ASF="active site serine inconclusive" /aSDomain="Thioesterase" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_FB479_RS17905_Thioesterase.1" /evalue="9.60E-55" /label="FB479_RS17905_Thioesterase.1" /locus_tag="FB479_RS17905" /protein_end="240" /protein_start="19" /score="178.4" /tool="antismash" /translation="RLFCFPYAGGGASIYRGWAQAFPSDVGVYPVQLPGRENRIAERAY SDMGELVEELAQVIHPYLDRPFLFFGHSMGTRIAFELARAVQSKWGRLPLGLIVSGGRA PHFPEPKPIYHLPDDEFVAALRRFSGTPEAILQSKELMQLFMPLLRGDFTLDETYVYAE EPPLDCPIAAYCGTEDQEATQEEMEAWASHTSAGFTFEMVDGGHFFLTTNKEVLLQSV" CDS_motif complement(42040..42102) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17905_0002" /evalue="7.40E-06" /label="NRPS-te1" /locus_tag="FB479_RS17905" /protein_end="103" /protein_start="82" /score="18.5" /tool="antismash" /translation="DRPFLFFGHSMGTRIAFELAR" CDS_motif complement(42262..42288) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_FB479_RS17905_0001" /evalue="5.30E-03" /label="NRPS-beforete1" /locus_tag="FB479_RS17905" /protein_end="29" /protein_start="20" /score="9.9" /tool="antismash" /translation="LFCFPYAGG" misc_feature 42403..42418 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 23.42" /tool="antismash" misc_feature complement(42405..42419) /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 21.7" /tool="antismash" misc_feature complement(42406..42421) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: medium, score: 25.81" /tool="antismash" misc_feature complement(42644..42662) /note="TFBS match to FuR_variant_2, Ferric Uptake Regulator, confidence: weak, score: 23.47" /tool="antismash" misc_feature complement(42646..42660) /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 20.63" /tool="antismash" misc_feature complement(42647..42662) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 23.02" /tool="antismash" misc_feature 42650..42665 /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 20.96" /tool="antismash" gene 42800..43408 /locus_tag="FB479_RS17910" /old_locus_tag="FB479_105337" CDS 42800..43408 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003339904.1" /locus_tag="FB479_RS17910" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105337" /product="MptD family putative ECF transporter S component" /protein_id="WP_142066198.1" /transl_table=11 /translation="MQAQTSLAAQSGRWTMRDMITLAIFNVVMLILMTIAPIITVVSHL LVGGFTALLNGPIYMVMSNKIAKPGTLFFTAVLTGLYFVGFGYANYLLTLAVIGLICEL ILWGKGSYLNPVRNAISYSVFYVGYSLCGVVPLIFFRESYLATLEKSYTPEQLSAMLYY FETPSMILIMCSISFVGGLLGCYFGNLLMKKHVKKAKLV" gene complement(43488..43763) /locus_tag="FB479_RS17915" /old_locus_tag="FB479_105338" CDS complement(43488..43763) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007728054.1" /locus_tag="FB479_RS17915" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105338" /product="hypothetical protein" /protein_id="WP_142066199.1" /transl_table=11 /translation="MDHQTYVEGSIAENEKVMTMKDWILVSLFMMIPIANIVLLFMWAF GSDGNLNRKNWSKATLLLMAILLGLYFVFGTIIAIITFILLAMEGQ" gene complement(43803..44084) /locus_tag="FB479_RS17920" /old_locus_tag="FB479_105339" CDS complement(43803..44084) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007728057.1" /locus_tag="FB479_RS17920" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105339" /product="hypothetical protein" /protein_id="WP_232030311.1" /transl_table=11 /translation="MEQQQHQEQWQVNVPENERVMSVKEWLITFLIMMVPVVNLVMYFV WAFGSEGNLNRKNWAKANLLIIGVCIGLYLSVFFLILMLAFIGAAVEQ" gene 44380..44634 /locus_tag="FB479_RS17925" /old_locus_tag="FB479_105340" CDS 44380..44634 /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) triceptide_precursor" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252063.1" /locus_tag="FB479_RS17925" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105340" /product="hypothetical protein" /protein_id="WP_142066200.1" /sec_met_domain="triceptide_precursor (E-value: 1.0, bitscore: 10.0, seeds: 0, tool: rule-based-clusters)" /transl_table=11 /translation="MNIKKNQVFVELEVANWDNTDLSSSLIEICYSQKEYENDLIEVHQ VVDLGKHKGNSKYLIIINITRDLDNLGDDLDNPYIVKGP" gene complement(44661..44900) /locus_tag="FB479_RS17930" /old_locus_tag="FB479_105341" CDS complement(44661..44900) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015892686.1" /locus_tag="FB479_RS17930" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105341" /product="hypothetical protein" /protein_id="WP_106656944.1" /transl_table=11 /translation="MDILERAGTVESREDMVQFISHLVKDYQQNKKEWANISLEEFLSG MESWIEDCDNMLADLEGVDWNLFATILIAGSRYE" gene complement(45088..45783) /locus_tag="FB479_RS17935" /old_locus_tag="FB479_105342" CDS complement(45088..45783) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252064.1" /locus_tag="FB479_RS17935" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105342" /product="hypothetical protein" /protein_id="WP_142066201.1" /transl_table=11 /translation="MKKMLSVSVVAASLLVTSAVGAFAAEKEGKVAGWKSLPEVQALKT LQMEQKALQDKLKAQSQINQQAWDVLWGDVTREVREQVKSALEETKPLREANKSLSAEL KEAKKAKDKEKVASIKAEIAANHTAIEEKLAHIQTELAQVKEKKASFKEMNQELKPIRT EKKANKEQAKELKTNEQNTVKEAKEAFQAGDKEQAAASLQEAADLLKELIQVQSEILEQ KQAISEIIQ" gene complement(45976..46443) /locus_tag="FB479_RS17940" /old_locus_tag="FB479_105343" CDS complement(45976..46443) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="FB479_RS17940" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="FB479_105343" /product="hypothetical protein" /protein_id="WP_106656942.1" /transl_table=11 /translation="MSYVTFDCTQFISFDSDNEADVAASLKEFEVTNHFKVLPKDEILP NKLEHLRHFLHSSVFEIVNQEFIGEFDEWLVREEVPVDILSFSRNIQLFMQNKHVQNAT VILVRYANDQKNEDRIFVGEFHKEHILEGLYHASCFGNAGNIVVLKMKSND" gene complement(46466..46648) /locus_tag="FB479_RS31280" CDS complement(46466..46648) /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF020904.4" /locus_tag="FB479_RS31280" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="hypothetical protein" /protein_id="WP_370511691.1" /transl_table=11 /translation="MPIALSVRNGYTYYAIDLGNEFGSIVCGSEPEFEEVEHIASSFDQ FLDKIMKNSVNFSLF" gene complement(46797..47216) /locus_tag="FB479_RS17950" /old_locus_tag="FB479_105344" CDS complement(46797..47216) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016743174.1" /locus_tag="FB479_RS17950" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105344" /product="hypothetical protein" /protein_id="WP_142066202.1" /transl_table=11 /translation="MFNINIDTNKLNSHLENISSWEDWYKIEKDIFHTDEWPRTSFDRL EEDLDRPVQIIEGCEWEPTTDSYDISPEVSHLYEKTRQKVFAILEPEADEDNKQHPELY GKRCIYCRIWTRDFSKQECPKCSNELLKFPLNEWD" misc_feature complement(47210..47224) /note="TFBS match to ZuR_variant_1, Zinc-responsive repressor, confidence: medium, score: 21.95" /tool="antismash" gene complement(47578..48174) /locus_tag="FB479_RS17955" /old_locus_tag="FB479_105345" CDS complement(47578..48174) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019636614.1" /locus_tag="FB479_RS17955" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105345" /product="hypothetical protein" /protein_id="WP_255438440.1" /transl_table=11 /translation="MTKTWTGLEINQMYYWQVRKYPPLLESEKDKPKISTWTSIIDIGK IYEDGPLTMSEYLRVEDKYVAAVLAYMNVLQVKDLEVYIINKLKEELFLDNINLYPDCY PPSIIEFYYSLNDGDILTGNHIDHIVRLGMREDIVCQLRNNDKFFVNFAYDFYMDIGSA IICEEAINEIKKIGLFIDLWKWPYPDNVWEKSEDL" gene complement(48143..48361) /locus_tag="FB479_RS17960" CDS complement(48143..48361) /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF026864.4" /locus_tag="FB479_RS17960" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="toxin C-terminal domain-containing protein" /protein_id="WP_142066203.1" /transl_table=11 /translation="MLGFEKVNAGRAKAAVFYSKERRVYITRDIPRESTGRTDNGGVWK MGESIESLMSRKTRMGTYDKNLDRIGD" misc_feature complement(48338..48349) /note="TFBS match to CcpA, Catabolite control protein A, confidence: medium, score: 18.48" /tool="antismash" misc_feature 48412..48428 /note="TFBS match to HexR, Glucose-responsive regulator, confidence: weak, score: 21.83" /tool="antismash" gene complement(48647..49153) /locus_tag="FB479_RS17965" /old_locus_tag="FB479_105346" CDS complement(48647..49153) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="FB479_RS17965" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="FB479_105346" /product="hypothetical protein" /protein_id="WP_142066204.1" /transl_table=11 /translation="MNQELRILIKKLIGGGITDLEFLDLFKGNIEITSYFDKLLEDICR EKNKDDLGLLFYIGFTFDLFDERHLEMLNQLITEAWHKTHEDIAGLLQYFQSNSSVESL YKAAITKFEYLHYTNALAVKCIWALGDINTPESKVKLELLSKSKEKEIKKNALHQLKRI TIKKL" gene complement(49156..55056) /locus_tag="FB479_RS17970" /old_locus_tag="FB479_105347" CDS complement(49156..55056) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016743179.1" /locus_tag="FB479_RS17970" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105347" /product="RHS repeat-associated core domain-containing protein" /protein_id="WP_255438441.1" /transl_table=11 /translation="MNTTEKLAGYENIQLVSPFEIQSLQDVRIVKKVNEHARLFVTGII PEEKSDRYIEMATSEDTVALNLVENGSLTKTLFKGLVDSVSVNFVHGVYHLELEAVSHT QRMDGQRKMRSFQHKQMTYASLLDEITKDYPGSDYLDHASNGAPLGTIAIQYQETDWQF LKRLASRFGSILVAEAVADTPKFWFGLPEGRTAQLTDASYTISKRLSPYMETTENGYAA GMSENDFLTYEVESGQVLQLGDRVNYQGKELVVAGSTTRIDHALLIHTYQLMPEAGIRQ NPIRNDDICGAALEGKIIDIQKDTVKIHLDIDPKQPKAEASWFPYATVYSAEGNSGFHC MPQMGDSVKLYFSTPDEEGAMAVSSVRKGGGSTAKTGNPGIKYWGTNFGKELMMGGKEL VLTAKESEEGNIFIKLHEEDGIEIHSMHPIVFSSEKDMEITSDTKVEIKAKEAIYLMCS TSSMILDGEVDLQAPKIEMVGLTKAPVVVEDLPQEEEEEEVVEEEQEEEKSGWGFLDSL QLGLDIVGMIPVIGEVADVVNAGISVARGDYAGAAMSLAAAIPGAGTAVTAAKLTTKAV KATKAMSKATKAVKAADKALGVSKAVKATANAASAVKGKVVTAARNIQESMDKLAAVQK LKKSMVGKFMQKPVVKEVFKEAGSEALDYATDGVFSTVTGMAWARKRIKGKHKKPGKVR KMNVKKVKPKSCIKDPIHGGTGAQFIVHPALKLYGAETWTFELHYNSLLLQEGALGKAW THNYEMRLEFLDETREEITVWWNTGRANTFTRVQDGLYRSSDADVFFDELRERQDGYTL WVKETRETYDFARNGQALRHTVAAGMSLLFSYDQHGRLNRLTEERSRRAFSLEYGVDGL VSALSDGTRSLRFSYDADRRMIRYTNPNGVVTDLSYTGNDQLESLASDGVIVYTNTFDE EGRIICQTDAAGIPGYIHYDTESRPGMMVTTFTDGNGHVEIMIHDDNGQLLEKTEKDGT VTKYSYNEWGQTTSETNGAGETTTYTYDHRGNLVKETDPLGNTTTYTYNENDLLTAEED AEGGVTTYAYDEHERLVSITRPDGCISSIGYNEHGQRSTYIDFTGAKTTYHYDGQGMLV SAQDPEGRIFRVGFDPTGRMTTFTDAFGGSLRQVFDANDNLVGVIDPLGRMHSFTYDTQ DCRVEETTASGASTKIGYTITEKVESITNAYGETTRYEYDKEWQIVGVVDPTGAKTSLE RDAMGRVTSVTDPLGNTQRYEYDAAGRLLAVYDATGQKVSGLTYDGAGNILAHIDGLGR STQYQFNKLHQVIATTNAAGQKTKFSYDAAARLTEVLENEAAVYKQQYDGEGRLTSYTD ANGNATTLSYDASGLLLAERNATGEGTTYRYDKRGWLTDKTNARGQETHYRYDAAGQLI EQQDEAGTVRRTFDAEGRVVSVKEDGKDTKRRTYDLLGRIASSTDQYGNTLQYTYDAGG RLETLIYPDGKTVRYTYDLAGQLTTVTDWAGRVTRYTYDENYRLIRTERPNGTVEQRHY DAAGQLLRLWDQNAQGVMLQQYRFVYNELGQIIQEEEKQYTYDALRRLTSGAMAGRKIL YTYDQGGNITAIGDSGSSLATAMTYAKDNRLDTVDGQQVQYDEDGNLLLLPGKQQPETY AYDARNRLVRAGQARYTYDAEYVRTSMTWNGKTTRYVVDQNADLTQVLMELEENGAAKA YYVYGLGLIGREDAQGDYLSYHADTRGSTTLLTDEHGRVTDRYTYGLYGELEAHEGRTK QPFCYNGRDGVMTDPNGLYYMRARYYHPGLKRFLNRDVLQGDMTDGQTFNRFAYVNGDP IGFIDPLGLMKCKEETGEVESEVYYRTMSEKHYKRLEKTKRMPGTGETFISPTKEYAAQ YEGVLVRFELKPGTTAKLEEIGLKNDSPITNARYPEMKDISSVSKWNEKYAHFKGEGLS GKKGIGKPQVNIGLGKGTALDIFNDNITSFERI" gene complement(55067..55492) /locus_tag="FB479_RS17975" /old_locus_tag="FB479_105348" CDS complement(55067..55492) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252071.1" /locus_tag="FB479_RS17975" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105348" /product="DUF4280 domain-containing protein" /protein_id="WP_142066205.1" /transl_table=11 /translation="MPMVEDVDVVPSSAPKKSYVVAGAILTCDYGSQKNKLKTPFSHGV YIRNQAQMNVNDYVPQVNIMPFGKCKCEKNPTVAAATAANNGVLKPMPCVPVVTMPWID GKADVLVENHPALLNTSTNMCIYGGCIRIEDDGQEQS" gene complement(55479..55955) /locus_tag="FB479_RS17980" /old_locus_tag="FB479_105349" CDS complement(55479..55955) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_017252072.1" /locus_tag="FB479_RS17980" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105349" /product="imm11 family protein" /protein_id="WP_255438442.1" /transl_table=11 /translation="MSDCSPPALSGRLDEAVIQFDIKQKKENDYLDFLDRPIPLYSNRL KTIIHKFAPKLFVKSVVLVDMERIKQDLYWLMILPRVNCLSEQSEFHRDGSLKRLVLDP EKIGRRTIFQIEGIREPYIIIDLRLAEALLRRDFFGIRLKKAEQAGRRMSHAHG" gene complement(56134..56586) /locus_tag="FB479_RS17985" /old_locus_tag="FB479_105350" CDS complement(56134..56586) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003202854.1" /locus_tag="FB479_RS17985" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105350" /product="DUF2004 domain-containing protein" /protein_id="WP_106657741.1" /transl_table=11 /translation="MTINDAVFGELEYNYAWFKDTTIEFCGEEVEIALMISGEQDGKFS EKQYAAYHSLIQSWEQLQQSILQPILDYYEQNYDAGLNENYPLIETAEQLLDYISLVGI SIPFAKGLEGRYIGLTFDCTWDEENGLGLLLINEEVARVGYQDVAM" gene complement(56950..57405) /locus_tag="FB479_RS17990" /old_locus_tag="FB479_105351" CDS complement(56950..57405) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_000657443.1" /locus_tag="FB479_RS17990" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105351" /product="immunity protein YezG family protein" /protein_id="WP_106657742.1" /transl_table=11 /translation="MKGFEERFSELQADMISICMEYVGDRANKVYVYASCEEDMISSSF FYLINNKYVECHKLNDVLEDGDESYDVSTERQFMVLNIINDNIEKIEELCKEFEKDMPT EMKLIYDATSGKFQAEYKYDLVHTNDDIKTADDFADEWFEEIKSKSL" gene complement(57424..>57783) /locus_tag="FB479_RS17995" /old_locus_tag="FB479_105352" /pseudo="" CDS complement(57424..>57783) /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF025298.4" /locus_tag="FB479_RS17995" /note="incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105352" /product="DNA/RNA non-specific endonuclease" /pseudo="" /transl_table=11 /translation="TDSLGRIGKFEMDNLQLTKRTERLSHSKNTPGKNVGHLAGDRFGG SPKIDNLVSQLSEVNQKKYKKIENKWAAALKEEPPKKVTVDVEIVYSGNNMRPDKFIVN YTIDGKAASAKFKNF" gene complement(58211..58678) /locus_tag="FB479_RS18000" /old_locus_tag="FB479_105353" CDS complement(58211..58678) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003202854.1" /locus_tag="FB479_RS18000" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="FB479_105353" /product="DUF2004 domain-containing protein" /protein_id="WP_106657743.1" /transl_table=11 /translation="MTKNDPIFGELEYKYSWSKDTHIHFLGKETEIALMIDGEEDGEFD EEQYTAYQSLMQDWEQLQQSFLQPILDYYQQKRHELGYDIAFNENYPLVETTDQLLEMI TLDGIVVPYGDIREGRDIGILFNCTWDQENGLGLRLLNEEVIEVGYQDVAI" misc_feature 58672..58688 /note="TFBS match to HexR, Glucose-responsive regulator, confidence: weak, score: 22.0" /tool="antismash" misc_feature 59038..59054 /note="TFBS match to GnfM, Regulator of nitrogen-fixation genes, confidence: weak, score: 20.69" /tool="antismash" misc_feature complement(59062..59080) /note="TFBS match to HgtR, Hydrogen-dependent regulator, confidence: weak, score: 23.56" /tool="antismash" ORIGIN 1 ttgatgtttt ccaaacgctc gattggcgag ggggataaag tttccaatcc agcgccaaac 61 tccggcagcg aaaaggcgtg tctgttcatt tctttaaagc ggtttcgtgc ttcgcgagct 121 tgctcattta ccggctgacc aggaccatca aaccacattt gtgttgtcat ttccaacgct 181 tcctctgtcg tgccacgctg acatacttga ttgaatcgtt ccacatcgtt cagcctttgc 241 tcacttcttg ggtgaccaaa caagccggaa gcgactagaa tcaagctgct caccatctgc 301 ggataagcaa gggcgaactc ctgcgcgacc attcccccaa acgaaagccc agccacatgc 361 gttttttcga taccaagcca aagcagaacc gctttcacgt cgtcgtacaa ggtaaaagga 421 acgtcagtcg ccagcgtttt accaaacccg cggatatcaa agcgaacgac cttatacatc 481 tgtgcaaatg cttgcagctg ggcatcccat agccttgtat ccagattgaa gccatggatc 541 aataggagcg gctcgccttc ccctgctact tcatagtaaa tccgtgcgcc attggcttcg 601 agaatgcccg tttgtacagc ctgcctgttt tccatttttt ctcacctcac acctcactat 661 ctcacccccg tttcttgctt gtccagatat ttcttcacgt tcatggtcca tttacccaat 721 gacgcctgtc cgtaaaatct tgacctggac atcaacatca aattgcgccc ttttcatgac 781 ttcacggcat tcgtctctat tcaatttctt ttttccactc ttttgacggg ctatgttgta 841 gatttccccg aatcctacgg gatctacctg gtgttttctt aacttttcca gtaaaccttc 901 cgtctctttt ttaactgcca gctggattgc tttttgtacc ttatgcaact cctccggctt 961 tgataaatct atttgttcag ccatttcctg aatctgtgct gtcattttga ccttcaccga 1021 aaaccttggt ttatccaaat ccagcagttt gatttgcttt ttgcttgaga tatgttcaat 1081 tacagtaaaa aaacgcttat tatcaacagt caagtttatt tccaattctc ccttattgta 1141 acgctcacgc aatatcttaa ggaaaaaccc ctcccttgtg gaaatctccc ccgccaatcg 1201 ttcatctcga aacagagcaa ttttgtcaat atgcagttcg ttttttactc tttcgatata 1261 aggcatcacg ggatctttcc cgaccgcata ataatctttc ataaactcat ggagtttaga 1321 ggaaatcata ttctcaccat tgacgttctg ccgtatagct tggtagaggt aaattccgat 1381 gttgctcgtt tcggggtagc gatgcgtcaa gatgtcagaa gcccttcctt tcgccaccgt 1441 caaatagaca ttgctgccaa tggaggcatc tcggctcaag ttttccacaa gcggcaatat 1501 tcctttgcgt gccagctcat cctgatagac agcgacacga atttgccccc ctactatttt 1561 tttggaagac tccctgttat gagtaatttt gagtcctttg cttgtattgg ctgttcccgc 1621 aatcacagtg acgagttgac gcgcctccgg atcaatttga taaaacaccg tggtacccaa 1681 caaccttccg tctccgattt gatcgtaacc cacggcaacc gctagtccca atttttctag 1741 tacctgttcc tccccacagc cattcaacaa agcggccatt agcaaataat aagctagcag 1801 acgtatcctt ttcatgtccg gaccgttcct ttccgaaaca gcagaataac gatataaagt 1861 atcaacggat aaacaaatat gatatagaag ccaaccgctc cgaaaatatc cgtgatccag 1921 ttaatcgact ggcgcgtctc caaaaagttg ctggcgaaaa acatgacaat gacaatcccg 1981 ataagtgctt ttctttcctt gaaaccacca atatggtgta ccccccgcat ggctacccac 2041 aagttcaaaa gcaaattatc cagcatgatc agcatccata atgagatgga aacgaattca 2101 aaccgctcca aaaacggaaa ctctactatt ttcatcatca tcagagttgc ccagatcaga 2161 tgtttaagct gttccccttg aaaatacagg agtgtaacca gcatgacgac aacatacaaa 2221 agagtggtca tcaacaatcc accatgtaca tagcgagaga gtaattgctt ttcctttaca 2281 aaagggtaga tgaacaaaat aatctcgaat ccaataatgc taaaagacat cttcctggca 2341 ccgtccaaca gctctacaag gtcatgatga aagacaggct gcagtaaatt aaaatcggcg 2401 tattgcgcgg gataaatcat caacaagagc tgacaaatcg tcagtccaac cgaaaaaaaa 2461 ctaatcccag ccaacactcg aattccacct gtcactccat aaatggccag acaaagcaag 2521 gaagcattca ataaccagga tggcacctct ggaaacatcc atgactgaat gatctcgata 2581 tatccccgca ggatcgttaa tgcagaaccc ataatataga tgataaatat caaattaagc 2641 actttggctg gccattttcc aaacaccatt tggtggatgt catacaaatc caagttttta 2701 tatttcctca agatttttag catgacccac gcggtcacat gcgtcatcaa acctgctatt 2761 atgaccgcaa tccaagcgtc ttgctgcact cgatcataaa taaagcgctg tacgcccgct 2821 ataccaattc caacctggtt gccatgcaca ataaacatgg caagggagac gctgataaac 2881 atatggctat gacgacgaat cgttgacatt cccactcaac acctaactac tgaattggtc 2941 ttttcttccc ggcttcatca ggcaaacggg cgttgtcagg agaacgcgtc aaagcgggac 3001 gcttgccgag attataaaaa ggaacccgga ttagactgtt tttaaaatcc cgcaagcgaa 3061 atggaaaaaa ggggagaaaa aacggacgtc ctaaactgga ctggcgtagg atgtgaatca 3121 atagaaaaga tgcgccaagc ataataccga agcctcccca aattccagcc agcaagatga 3181 ttggaaaacg gaggatgcgt actgccgtac tcatcatgta ggaaggaaag gtaaacgacg 3241 ctaatgcact tagtgccaca atcataatca gaatgttact ggtaaagccc gctgctacgg 3301 cggcctgtcc aataacgata ccacccacga tccccatcgt ttgcccgact ttgaaaggaa 3361 gtcttgcccc agcctcccgc aagaattcaa tgatcatctc cagcagcaaa gcttcaaaca 3421 atggtggaaa tggcaccttg gaacgagact ttaccaacga tacgagcaaa gcagagggaa 3481 tcatttcata gtgaaacgtc agggcagcca catagatagc cgtaaaaaac aaggagacaa 3541 atagagcaag gaaccgcaac aatcgaataa aggaagccat ttgccagcga atataaagat 3601 cttcattgga cttgaaaaag tcaacgaagg tactgggacc catgatagca aaagggctgc 3661 cttccacaaa cacgataacc tttccttcca acagagcttc acttgcataa tcaggacgtt 3721 ctgtcatgat caactgcgga aaaatagaaa aggtattatc atcaatcagt tgaaccagtt 3781 ttccactgtc aatcaatcca tctacatcga gttctctcac acgctgaacc acggtttgaa 3841 cattttcagg atcagccagc tcttccatgt aacatacttc cacattcgtc ttgctgcgtc 3901 tccctattgt aatagagacg ttagagagca tatccgttgt tagatagctt tgcaggatcc 3961 cgaagttggt ttcaaatgct tcggtaaaag caacctgggg accgaatatt tgtacttcga 4021 cctgagcctc tcccaaagaa cgactcggta tattagccac gaagagaaga agtccgcagt 4081 cttctccttc tatttgaagg taaatccatc ccctcacgag ataatcactg acttgtctgt 4141 aatcaatcgt cttgcgaact ttagcaacag ggaggttccc caaaagagta tcaggcgcta 4201 tcttttcgtc gggcaacctt tctaaaaagg gaagcaaaac ttgctggaga ataaccatat 4261 caatgagata cgggaggtac gctaacaaca agctattgtt tccacaggat agactgcgaa 4321 acgacaatcg cggatttcgc atttgttgcc ataatatttc ttgcgtctct tgaatggaat 4381 caggaatcat gttggttgtc attttctatt accccaataa atggtgtacc cttattattt 4441 tccaaatctc tagctctatt cccctttcca gccgaagagt aggtttccac ccatatgaag 4501 aaacaaaaaa accgagacgg aagtactcca tctcggttcg tatacaacta tttatctgcc 4561 gctcttcatt tcagtccagt agcggtcgta ttgctgcaag gtttctccta catccaccag 4621 ccactcggca cgggcaatgt ctgctttatc cacgaagacc atcttgttgg aacgatattc 4681 ttcactgtgc agtgggtatg cttgttcgtt cgggttgctg tagccgatag actcgtagtt 4741 tttcacactg acttgtgggt ccatcagata gttgatgaac ttctcagcca tttccttgtt 4801 cttagcgcct tttggaatgg ccagcgtgtc tgcccagatc gttgcgccct cttttggaat 4861 gacgtactct acatctggat tttgtgcgtg aatgaaagcg gcgtcaccgg accaaaccgt 4921 tccgatccat gcttcctccg caatcatctt ttgcttgatg ttgtctgtat caaaggcaac 4981 aacattcggt actacctttt tcaaatcagc aaaggacttt tccagttcct ctgtgttcgt 5041 cgtgctgttg gagaagccat tcttgatcag tgccattccc ataacctcac gcgggtcgtt 5101 tagcatgatg acacggccct tgtaggcttc attccacaga tcgttccagc ttgtcggggt 5161 ttcttttaca tatttcttgt tgtaagcgat cccggtaatt ccccatgtat atacgagtga 5221 atacttgttt tctttgtcaa aaggaggtgt cttgaacgta gacacgatat tgcccatgtt 5281 cgggatgttg gctttgttca gctcttccag gaggcccagc tgaatcatgg tgcctaccat 5341 gtagtcggaa ggttgaatca agtcgtagcc ggatgcaccc gcttgaattt ttgccagcat 5401 ttcttcgttg ctgccgtata catcatagtt aaccttgacg ttgaattttt gctcaaaatc 5461 tttgatgacg tctgggtcga agttgtctgc ccagctataa atattcaata cttgttgctc 5521 ttgctcaggt gacgatgagc agcctacagc agtcaccgca agtacggcgg tcaaagcgcc 5581 gatcatcaag gacttgaaac gtttcatttt ttcctctcaa cctccaaatc agttatggga 5641 ttgcttttat gaaaacacca tgatgtatct aaaagatgga ttgattattt ttcgaatctt 5701 tgcggcggaa aatctctgcc accacaacca acagcactgt actcacgatc aaaagtgtcg 5761 agagtgcatt cacttctggc gagacgcctc gttttaccaa cccataaatg tagagcggca 5821 atgtggtcga attcggacca gccacgaaga acgaaatgat gaaatcgtcc agcgacaagg 5881 taaacgccat caggaagcct gcgatgatcc ctggcatgat cagaggcagc gtcacatagc 5941 gcaatgtctc ccatggagtt gctcccaaat cttgagacgc ttcttccaat tctttgccca 6001 tatcagccaa acgtccagag ataatgacca tcacatacgg catgctaaac gtaacatgcg 6061 ccaggatcag ggtcactttc cccagctcca tctgtacctg gctaaacagc acgagcaaag 6121 ccaaccccat catgatctcc gggatgacga tcggcaagta catcagcccg ttgaagatgt 6181 tgctccaacg cagcgaataa tgcttgaccg ccagagcggc agccgtacca aaaaccgttg 6241 caatgacgct gctgataatc ccaatcgtca aactattcat taacgcttgc atgacctgtc 6301 tgttttcaaa caaagaaacg taccacttcc acgtaaagcc agtccacgta gcattgatcc 6361 gtgaatcatt gaacgaataa aggacaagga tcaagattgg cagatacaaa aagaccagca 6421 tcagccacga gtatccagat agtgcgtttc gacgtaatgt tttcatgccg atccctcctt 6481 tgtctcactc gctttggtag cgcggaaata aagaagaatc aacagcatgg acaatagcat 6541 cagcacgatg gacaaggcag aaccgaacgg ccagtcacgc gcagacaaaa attgattttg 6601 aatgacgttt ccgatcagtg ccgatttcgc tcctcccatg acatccggaa cgacgaacat 6661 cccaatggaa gaaacaaata cgaggatcga cccagtgaca acacccgtct tggtcatcgg 6721 caaagttacg tgccaaaaag ctttccaagg tgttgcgccc aggtcatacg ctgcttccag 6781 cttgcgacga tccatctgct ccagtgacac ataaatcggc agtaccatga acggcatgag 6841 tgtgtacacc atcccgagca gtacagaacc ggaattgtac aacagcggca gcggctccga 6901 tataatgccc agcgattgca ggaacgtatt gattacgcct tgcgaacgca ggatgattac 6961 ccacgcatag gaacggacca ggaagttgat ccaaaacgga atcatcacga gcaaaagcca 7021 tatctgctga gtcgattttt ccagccgtga tatgtaatac gctaacgggt agccgcacaa 7081 gatcgaaaat acagttgtta aaaccgctac gaccagcgta tccccaaaaa tttggccata 7141 cagcggatcg aaaatacgga tgtaattgtt cagcgtaaac tcatagacaa cttgcccgta 7201 cgtgcctctt ttgaggaaag acaggatagc gatcataagc ataggcagga cgaaaagcgc 7261 acccatccac aaaagggcgg gaagcgcgag cagttttacc ggcttcttgt ttaacaagga 7321 agaatcacct cgtccgtctg tgcccagcca atggccactt gatctcccac ctgccagtcc 7381 agaccgtcac ctgcgtactg gtgtgccatt acggtcatat cctgcccctc gaggcggata 7441 aataccttgc gcaaattgcc gaggaacacc gcgtcagcaa tggtgcccag cttcttgtgc 7501 ttgtccttat cggagtcaat cgggtacaac ttgatctttt ctggacgtac ggctgcattc 7561 gttccgtttt cccggaaaat gttgttttcc ccaataaagg tagccacaaa caaggtttgc 7621 ggggagttgt aaatctctgc tggagaagca atttgttcaa ttcgtccctt gttcataacc 7681 gcgattcgat cggacatcgc catcgcttct tcctggtcat gtgtgacgta aatgaacgtt 7741 atccctaagt tcttctgcaa gtttttcagt tcgagctgca agctttttcg caattgatag 7801 tccaaagcac ctagaggctc gtccagaagc agaacgcgtg ggttgttaat aatcgcccgt 7861 gcgattgcta cgcgttgctg ttgtccgcca gacagctgct ttggcgtgcg cttccgcaat 7921 tctgtcagtt ggacgtactg aagtacttcc tctaaacgct tttgttgttc agctgcgttc 7981 acttttttca ttttcaaacc aaacaggatg ttttgctcca cggtcatgtg tggaaacaaa 8041 gcatattgct ggaacaccat gttcatatcg cgctgatacg gcggcacagc cttaagtggc 8101 ttttcgtcca ggaaaatttc ccctgtcgtt ggctgctcaa agccagcaat cattcgcagc 8161 agtgtcgttt tcccacagcc actagggccg agtaacgtca aaaactcccc ttcttcaatg 8221 gagagagaaa aagaggggac gacgacagta tctgcaaatc tcttttcaat cgaatccaga 8281 tgtataattt ttttcattcc gtcatctcac catatgtcat tatactcata caatctaggt 8341 aactatatcg tgtatgctac gatttgtaaa cagtttcacc aagtctggaa cgattttttt 8401 gcgaccagca aagcagagcg attcctccac aaaaacaaac agagcggatg aataaacatt 8461 cgctctgttg cgtatccttt ttattttctc acacagaggt tgatttcgtt tgaggcgtgc 8521 gattttggtt tttcgatttt gcccctagga aattcgtccc aatcaccccg ataataatca 8581 tcactgcgcc aatgagatgg tagtatgcca attgttcctg caaaaagata acgcctgcca 8641 cgatggtaac caatgtagac agattgttaa acacgctgag tttggatgcc tccatcttgg 8701 acaaggcaaa gttggtcata aaagacgtca tgagcgagga cagtatcccc aaaaatacaa 8761 tcgagatgat aaaggccgag ctggcgaaag gggcaaaata cgtggacaag gtcccctctg 8821 cactatggcg aatgattgac cagccgttaa aaaatataaa tccgagtaac gccaccatat 8881 acgtcatgtc tatataatga aaggactttg tcattttcct cgccagtaca ctataccccg 8941 ccatagaaaa cgcggataac aggatgagaa tggtaccgat actgctccct gagcctgagc 9001 ttacacccag ccccttcatg gcaaaaatgt acacgacacc tcctacggat aacagcgtgg 9061 acagcttttg cagccaggta gaagactctc ccaaaaagaa tgccgccatg atcatggtaa 9121 aaatcggaac ggttgcttga ataatccctg cttcagatga agtggtatac accagtccaa 9181 acgcctgaag ggtaaagaac agaatgggat acagcatggc gagcggtata attgtgagca 9241 tgtcttttgg tttgatggac agcttgatcc atccaaacac gatcggaatg gaagcagcga 9301 taaaggccac ggtaaaacgg tgtgccaaag tatcaaccgg attggttaca gcgagtgcca 9361 ttttcagaaa caaaaacgac aagccggtaa tccctgcatt cagtaatgcc gcaacaatcg 9421 ctttttgttg gtctttcatc gtatgtatct ctcctactgg ggacttttta cagacggccg 9481 tcttaggtta atagtaatgg gggatcaatc gtgctacaat gcaaaaaagg agtaactgta 9541 ccgatacaaa ttcagcggta agggaatgtt ttttggatgc acaaatattt gcagcttcaa 9601 aatgaactcg aaacgttgat tgaaagcctc tcctatcgag acggcgaccg gcttccctcc 9661 atacgggagc tcgcctctcg ctaccaatgc agcaagagta ccgttatccg caccttggat 9721 gagctcgaaa agcgtcatct catctactcg gtcgaccgaa gcggctacta cgtcgtgaaa 9781 aaacaaagga agatacaacc cgcagatacg tcgatgatcg attttgcgac ctctgctccc 9841 gatcctgacc tctttcctta tatcgacttt caacactgca tcaataaagc aattgaaacc 9901 tataaaaacg atcttttcat atacggaacc acacaaggct tgccatcgct cattgccgtc 9961 gtcgccaagc tgcttgggaa ccatcaagtt tttacagacc cgggcaatat tttcattacc 10021 tccggtgtcc aacaagcact atccttgctg tgcagtcttc cttttccaaa tggcaaagaa 10081 acgattctga ttgagcagcc cagctaccac cttttcattg aaagtttgca agtacgcagg 10141 tatcctgtcg tcgggatcaa gcgcactgcc caaggaatcg atttagaaga gctagagtct 10201 attttccgaa cgggagagat caagtttttc tatacgatgc ctcgctatca tagcccgctc 10261 ggtacgacgt acagccgaaa ggataaacag cgcattgtgg agcttgccca acagtacgac 10321 gtctatatcg tggaagacga ttacatggca gatcttgagc atgacagcaa agcggatccc 10381 ctctttgcct atgaccgcta ttctcgcacc atctatgtaa aaagctattc caaaattatt 10441 tttcccggtc tgcgtttggg tgtagccgtt atacctgacg cgctaaagga ttccttcaac 10501 cagcacaaac gactcatgga tatcgacagc tccatgctat cgcaagctgc gttggaaatt 10561 tacctaaaaa gcggaatgtt cgagcgtcac aagcaaaaaa tacgcagttc ctatcatcgg 10621 cgatccaacc tgctgatggc gtccttgaac catttcacgg cgaatgaaga tcatctgttc 10681 acctttcagc cccttgctta tccggggatt catacgcaca ttgttttgaa cgattccatc 10741 ccagttcccg ctgttatcag ccagttaaaa aaacgctcga tcctcgtgga ttctattgat 10801 aaaaattact tgatgggatt tccgcaagaa aatattttga agctgaatgt gtcctatgcc 10861 aaggaagcag tgattgagca agggattcat gtgctgatgg atgtgttacg ccgcatgcac 10921 cgataaccta tccgccttaa gtcgcagata aaatccggcg agggtgcgtt tttggacaac 10981 caataaaagt gtgattgttg agtaacccga gaaccgtcta catcgtatta tcagatacag 11041 gaacatagtt gtggtaaatc gttgtatagt aagtgaatcc caattcaaaa aaattcgttc 11101 catagtcggc cagtttgaag tagaatcgca tctatacaca tataatttgt tgggcttact 11161 cggtgtgaag ctgaatattc cgacaaatcg cgcagacctg gtacgatccg actcgattga 11221 gttgatgact ggcagttaac gatagaatga caaaggagaa atagatgttt cagaacattt 11281 tagatttctt aatggaatac ggctatatgg gaatgttcat ccattctttt gcagacgcag 11341 tcatctttcc cgttcctgcc ttctttcttc aagtgccact cagcctcgtt gatccttcgc 11401 aggcattgtg gattgcaacg gtaggctaca tcgcttgtct gttagggaca cccgtcggtt 11461 attttctcgg taaagtacta ggcaaatccg ttctttacaa aatcctcaaa aaggaatgga 11521 ttgattctgc cacagagatg tttcaaaaga agggcgaagt cgcgatcttc attggttcgt 11581 ttacaccgat tccgtttaaa gtatttacta tcatgtcggg ttgcttgaac ttcccgttgt 11641 ggaaattgat cgggtatgcg gcaattggac gggcagtcaa attttacgca gtcggatttt 11701 tgttttattt ttacggcaaa atggcggaaa atatggtcca tgacgtttct ctctatatct 11761 ttctcaccgt ggtgccgctc atcttggttg gattatgggt gaagaaaatc gtcaccaagc 11821 gccgccagct gaaaatggaa agtactggcg tcagcaatgg catcaatgag aaagtcatga 11881 ataaataaag tcgataacaa aaagcaaaga aaccccacat tggggtttct ttttttacga 11941 ctgttatcct tttttcacac gaatcacatc atcttctaca tcaatgacca tggctgttac 12001 attgtcttct tccatcacca aatccgcaat gccatcctcg acgtattgct gaatcacgcg 12061 acgcaatgga cgtgccccga aggaagggtt gtagcccagc tcagccagct tttcttttgc 12121 ggcatctgtc acgctgatct ccattccttg ctcagacaga ttgcccatga catcttgcag 12181 cagcagatcg acgattttga ccaaatcctg ttttcccaga tgggcaaagg aaatgatcga 12241 gtcgaagcgg ttcaggaact ccggcttgaa gtacgctccc aaagaatcca gcacggttgc 12301 aggttcgggt gcttgtgctc caaagccaac ggagatttta cgctcgctca caccggcatt 12361 gctagtcgca atgatgaccg tctccttaaa attcactgta cgaccctgac tgtctgtcag 12421 acgaccatcc tccagaattt gcaggaacat gtgcatcacg tccgggtgtg ctttttcgat 12481 ctcatccagc aggataatgc tgtacgggtt gcggcgtacg cgctctgtca gctgacctgc 12541 ttcttcatgc ccgacgtagc caggaggaga accaatcaat ttggataccg agtgcttctc 12601 catgtactcg ctcatatcga ggcggatcat ggaatcgcgg gtaccaaaca gctcctctgc 12661 cagcgctttg gacagctctg ttttccctac gccagtcgga ccgacgaaca ggaaggaagc 12721 aatcggtctg tttttcggtt tcagacctgc acgactgcgt cgaatcgcct tcgctacttg 12781 tgtgaccgcc tcggattgac caatgacttt tgcttccaaa tgagctgcca ggtttttcat 12841 tttcatctgc tcatcacttt gcagcttcgt aacaggaatc ccagtctttt gctcgatcaa 12901 ggcttgaatg tccgtgacgt caacctgaac gcgttgctcc ttgccctcga tctgatccag 12961 cttctctaga atacccgctt cctcgtctct cagacgggca gctcgttcgt aggcctcttg 13021 ctccgttgct tcctttttct cctgattgat ttgcgccagc cgctcatgca gctctgccgt 13081 atcaactgcg gaggatcgca ggttcaaacg cgagcccact tcatccatga ggtcaatcgc 13141 cttgtcaggc aagaagcgat cctgaatata acgatgggag tattccacgc aggcacgaat 13201 gacatcatcc gagtaagcga cttggtggaa tgcttcgtat ttcggacgca atcctttcaa 13261 aatctcgatg gcttgttcta cggttggttc cttgaccatg actggctgca ggcggcgctc 13321 cagagcagcg tctttttcaa tcacgcgata ctcttttaac gtagttgccc caatcagctg 13381 caactcaccg cgagccagtg caggcttcag gatgttccca gcatccattg atccttccgc 13441 tgagcctgct cccaccagaa gatgaatctc atcaacaaac aggatgacgt ttttgcgttt 13501 ttgcagctcg gcaatcactt gcttcatttt ttcctcgaac tgtccacgaa ttcccgttcc 13561 tgcaaccaga gaggcgacat ctaaaatgta cacctgcttg tttttcagct tggtcggtac 13621 ttgcccttcc gtaatacgca gggcgagccc ctccgcaatc gctgtcttcc cgacccctgg 13681 ctccccgatc agaaccggat tgttcttgtt gcgtcggttc aaaatctcaa tgacacgctc 13741 aatttcctgt tcgcgtccaa tcacaggatc aatcagtccg gcacgcgccg catcgtttag 13801 attacggccc aggtcatcga ggatgcctcc gccacgctct ggtgcttgtg gctgcggttg 13861 gctggacgat ttgcccggat tcacccggcc ttgggcaaag ccttgcagga actcatccag 13921 tccagagaag gaggagaaag gactaaagcc catccctact cccattttgt tggtcagctt 13981 tgttttgcaa tcctggcaca gatcgtattt ttgttgctga ttttgtacac gtatatgaac 14041 agtcacagtt gcttctcgtt gtttgcagat ttcacaatgc atattcaatc cccccaaaag 14101 cgttgttttg gaattcagaa gatctttgac cttccctgac cttcgttgac tttattatag 14161 tttgaccttt tttgactttc aagagggatt gtatggtttt ttacactttg ctcttttgca 14221 gatagggaac gattgaaagt aacccaatac cagctaaaca agcacctacc cacaatggtg 14281 aaacaagccc atagccactg ctgatcccga tcccccctaa ggaagatcca atcgcaacac 14341 ccaatgtaat aaaggaagta tgcacagtgt ttaccatcgt cccactgcct gctgtattca 14401 tgacgcgtgc gatcatggcc ggattcatcg ctacgcccgt caacccaatc agaacaatgg 14461 acagcacagc gatccattta ttttcggcgc ctacggcaaa cagaaccaat gccgctacga 14521 gcatgcttaa tcccgttaca aggattcgca tggtgaaacg atcagcaaat ctgccaatca 14581 cgatatttcc gatcacggtc gcgatcccat aaagcgcaag caaatacggg atgctcgcag 14641 ccgaaaatgc cgttacatcc gtaagaatcg gagtaaaata actaaacgct gcgaaggtac 14701 cgccaatgat cagcatactc gttgcatacg cggcccaaag gtgcggattt tgaaaactgg 14761 caagctcatc ctttccattc atctggtcct tttgtgcgga ggaagggagc aaccattgaa 14821 tcaagatccc tgatagcaat acgactactg caacagccca aaagctcatt ctccagccga 14881 aatattgtgc aatcacggtt gtcagaggga gtccgatgac agtagcaatc attaagcctg 14941 ccaaaacaat cgaagctgcc tttccccgtg aatgaggggg aaccaagctg gctgaaatac 15001 tgacggagat gccaaacgct gcggatgaag cgatacccgt taggatacgc gcaagcatca 15061 tcgactcgta attccaagcc attgctccta acgcttgacc aataaagaag acggcaacca 15121 atgaaagcag cgcttgtttt cggcgaatgt gcaggagagt tgctgttagg atcgggcctc 15181 ctatcaccat tgcacccgca tacgccgtaa tgaaataccc gatggaggga atcgatacac 15241 cgaaatcatc ggcaagctca ttcatcatcc cggccaccat aaattcagaa gtcgtcatcg 15301 caaaaattgc taccgctaac aaataaatca tcgacggcat gaaggaacac ccctcgctca 15361 ttattgtaac aatcggtaca aaaatcactc aaaaaaagag cgcattacgc gccgaagata 15421 gattccatgg tgccactcat gatttgttca gccaatgtcc gattttgtgt agatgtattc 15481 aacacacgga agccgtagta gctgcttaaa aataggcttg ccaaatccac agcagatcgt 15541 ttttggggga tttcgcccgt ttgcaagcct tcctccatca ctttttccat ggcttgcttt 15601 agaagttcaa catgtctgga gacgatttct tcaatcttgg gttcgtcttt tgcccgttcc 15661 aatcccgcat tgatcaacaa acatcccttt ggattcgttg attcaaagtc ttccaccaat 15721 gcccaagcta aaaaattttg caaccgttct ttcacggaac ccggactttc caataatgcc 15781 cgctgttcac gaatacccgt ttcgtgatag tgttccacca ctgctagata caggtcctgc 15841 ttgctgccaa acgtattgta caagctgcct tttcctagtc cagtatcact gcataaatca 15901 tgcgtagaac aaccattgta gccttttgac caaaatgttt tcatggccac atctacgata 15961 gaagtgtaat caaaatcacg aggtctgccg cgtttgctca acggaatcct cccttcgttt 16021 ccaactgtta tggaaatttt acacattatg taccgatcgg tcaacaaatg agatgtctgc 16081 aactgtaatc catccatgca tatagaaaaa gcccattttg aaaatcatct ctcaaaatag 16141 gcttgatcat ggattatatc gtctctaaat ctgttactgt tttttcgttt acttgatcgc 16201 cagtattcag cgtcgtcttt ggttcaagca acaatacatg aacctcttcc tctgcaaccg 16261 gcatatgctc tacacctttt ggaacaatga gaaattcccc ttcgtttaac caaacatctt 16321 tatcacgaaa cttaataagc agttgccctt tcacaactaa gaacatctca tcctcatttt 16381 catgctgatg ccagacaaac tctcctttta atttcgctag ctttacatag gaatcattaa 16441 gttctcctgc aattttggga ttccaatgct catggaataa cgaaaacttt tcagctaaat 16501 tgaccttcat cattattctc cccccattaa aaagagtatg cttgtacttc atcgaacgta 16561 ggcagggatg gttgcgcacc attccttgta acgacaatcg ctgctacttt gctggcaaaa 16621 gtggccgctt ccgtttctgt cattccttgt gtgatcccaa ccgcaaatgc tgccgtaaag 16681 gaatcgcctg ccgcagttgt atccactggc tctacgcgga aagccgggat gtgggtcgcc 16741 tcatcggagg ttactaagag agcgcccttt tcccccaacg tcacgatgac gcgctttggt 16801 ccgccagaca aaagcttttt ggctgcggca tgcacttcgt caatcgtgga tacgggcatt 16861 cccgtgagaa tagaaagctc tgtttcattt ggggttaggg tatgtacatg ggttaatagt 16921 tcactggata gctcgcgtgc aggtgccgga tttaaaatga ccagcttgcc gagtcgagca 16981 gcctctttgg ctgtatattc cacgacattc atcgggattt ccagttggag caatacgacg 17041 tcgctgtcct ttaaaataga cagattgtct gcaatatgct ccgtactgac gagcgcattc 17101 gcacccggaa cgagcacgat gttgttttcc ccatcatcac tgacattgat aaaagccatg 17161 cctgtcgtac ccgagcgttt aatcccttct atgtgaacgt gcgcatccgt tagccctttg 17221 accatgacct ggccgttctc atcttctcct accattccaa tcatggagac atgcgcacct 17281 aggcgagatg ccgctactgc ctgattcgct ccctttccac ccgggatcag ctcgaagtga 17341 tggcttgtga tcgtttctcc tgctttgggc aaatgatgta catgggttac gagatccata 17401 ttgatgcttc ctactactgc gattttcaca acgagccctc ctcgttccat ctcgaacatg 17461 atgattcggt cggttacaaa atagtgcttt tcatccgaga agtcaacgta ttttctaaag 17521 gattgttccc aagacttgga gcacagcgcc tcctttggat ataatgaaca aatcttctat 17581 catccggagg taaccagatg gagccgatta tccaacatcc ttggaacatt gatgagcaag 17641 aggctatcaa cttacagcga caactagccc agcaagtgaa aaaagaagat caactagcgg 17701 acgtacgctt tatcgctgga gtagatgtcg cctatcatgc cgagtctgat ttgttagttg 17761 ctggtgtcgt aatcctcgac cccacttccc tgcaagtcgt cgaatctgtc gttattcaag 17821 acaccgttga gttcccctat attcccggct tgttctcttt tcgagagctg cctccactgg 17881 tacgtgcatt ccaggagcta aaaacaacac cgcagctcgt cgtctgcgat gggcaaggaa 17941 tcgctcaccc gcgaagattc ggactagcca gtcatttggg cgtcctgttt gacattccta 18001 ccattggctg tgggaaaacg agactgttag gtgaatacga agaaccagca caggaaagag 18061 gcgtgtattc ccctttgatt gatcaaggtg agatcatcgg tggagtcttg cgcacacaac 18121 cgaatatcaa accgatcttc gtctcgatcg gacacggaat ctctttgcca actgcatgcg 18181 catggatcac caagctctct cccaaatatc gtttgcccga aacgacgcgg caagcggatc 18241 agctcgtgaa taaagtatcg gcggatttaa acagcagccg ctaatggagt gtcggccata 18301 cattttcatc gtgctcatcc aagactgctt caatctgatc tccttggaaa acgacaatgt 18361 agcctcgtgg cagagccaat gcttgcaaaa gagacggacg tagctttagc agttcgtaaa 18421 cgtagtagga cgctagctgg tcactgtcta cttcgccttc tactggcccg agataccatc 18481 cggagtcacc tttttgaaca tcttcagcac gctgcaaata gacgtgttct tgttcaaatg 18541 caccttttgc caccaccatt ttatcttgga acaaagcaga ttccccttcg gctcgcacgg 18601 tttgcagaca gttgttttgc gccatttgca caaccaagga cactgacagg tcagcagtag 18661 tttcggaaaa aggattcgaa tcgtagtcgg gtgccacgat ctccatatac ccatcccgtt 18721 cgaaaaccag cagaatggtc caacctacct gaattttcgc accgttcttg ataggaccaa 18781 tctcgtcttc tacatcggcg aatacgtcca acagaaagtc tgcttgcttc accaaaaact 18841 ctttgcaggt cacgacaaac gtacggttat gaatctgttt ggagcgttgg cagagtcggg 18901 actctttctc agctgacatg gacctcttcc tttctgcgtg atcggtattg ctgctatctt 18961 caggatatca cgaataggcg aaaagctccg ttacactttt gctacaaagg atatgtacta 19021 actggctgac gaatgaactg caaagcgcgg cttggcaggt gggctacagc gttttttgtt 19081 gtatttgttc gatacagtct ttgatcgtat caatgacgac tttgggctcg gtaaattgag 19141 gaaaatgtcc actgttttca gcgaggatat gtttgctgtt gcttgataac gaaagcagtt 19201 ccaactgatg ctcgattcgt tttttgcgca cttcctctgg catcatacga ttttctttcc 19261 cccctgtaat cacataaaca gggatgtcgg gaaaataatc gattgcatgg atttgttcta 19321 ctgttctttt gacaaaatga acttcattga atggtttatg gggagacaag gaatcaaaca 19381 tggagagtat tttgttaatg gttttaacta ctttaccttg atattgatca aggccgatat 19441 cttttggatg gctggattct aaaaagacga tgccagctac ttcgttgggg taatgtcggg 19501 catataaatt tgcatacaat ccccctaatg aatgtccgac tagcaagaat gggggttcaa 19561 atcctactat ctttagtgcc tcccgtaatg tttctacaat cgtgagtccg tcttggggct 19621 cttgcggctt atcactaccc gaaacaccaa agcgattata ggaaaagaca gatgacgtct 19681 ctgaaagttc aggtagaatt ttcatccagc cttctatagg tcctgaacca ccgttgatga 19741 gaacgatatt gggtttgccg ttcccgctcc aatgatattg gatcttccct cttgaagtac 19801 ttactttcga tctctttatt gccaatgtac gacacctcac tttgttaggg ctggatttca 19861 ctgtagtaat acgcgatgaa caaatgaggg tttctatttt ttaggaataa ttcttgcagg 19921 gaggaaaagg agcagcggcg gacaaaggac attatttttt cgtccttgtc taccgctgtt 19981 ttgattgcta aacgatgaag ttatttggtg ccgagtggta ctgccaacag ctccgccagc 20041 ttgaccgcat tctctcctgc catgcagctg taatggttgc cggcgatttc tgtcacttcc 20101 aattctccaa tgcatatatc ttgccaaaaa gcgatggtct cttcgctcgt gcttggcaaa 20161 aattgaaacg gctcgcaagc cagcaggaag cgaatgtctc ccatataagg caaaggagta 20221 tagcgagctg ctttaaaact ctgcccaaac actttgcaca agccctctgc catttccacg 20281 ggcatctgtt cccccgatgt tttgcctagc gcatggacat aagcagtaaa gcgttctctt 20341 ctgtcaaacg cggataattt gcggaacatc tctcccacct gatctagccc ctcgtctcca 20401 ccgatggtgc acgctgagcc ttgcgggatg caatctccgt atttttctac aagctgcaaa 20461 atcgcccgtg cgaaatcgtg ctcatccact tttccaaaat cagcctgttc cagcgtgatg 20521 ttcaggttcg gaacgaaaag tgcctcaatc aagagatcgt cattcacttc tgtcaggatc 20581 ggaggaatgt cgatcaaaac caggtccaga atcgggacgc cctgctcccc gagtcttctc 20641 gccacttcaa tggcaatcaa tccgcccaag gaatagccga tgagctgtac aggtctttgc 20701 tctccttcac gcaagatgtc gatcaagcat gcggcataat catcggccac ggtttctatc 20761 agctcagacg gctctagtgc gcaataacgc tcactatcgt caatggcgat cccgacgatg 20821 cttcctgtct gctgggcttt gagctgttca atcaatggac gaaaactgtc catcgtcccc 20881 aaaacggcat ggaacacaac ccgcagcgga ccagatgcgt caccgccata tggaatcagc 20941 acggcattgc tggacttgtt gcgtcttgtc ggcaatgcga cttcctcact ctgctgcatc 21001 tcctgattgc gcatgtgtag gaagccagcc agtgcttcca cggtcgggaa gttgagcatt 21061 tgccgcagca agacatcaaa cgggatggca gcgtgcgtcg ggtcctccgc tagcttgtcg 21121 cgcagctttc cggctacctg tgccatgatg agagaatctg caccgtactc ataaaagctt 21181 tgtgttctgc cgattctcgg gactcccaat gcttctgccc agacgtgagc aagctgcgct 21241 tccaacggat ctgattccgc cccttctgta gcgtccctag cagcatgttg tccgaacgat 21301 gatgcagggc gccattttgc cagctcgcgg cgatctattt ttccatttcc ggtaagcggc 21361 agtgcgtcta cgacttgcaa gtgggcaggc agcatataag caggcaggtg tagggaaagg 21421 aatttttcca gctctgcggc actgaccctt accctgtcca gcttcacctg atgagcgagc 21481 agatgattct ctccctcctt ttgcaacaag aacacaagag cgtcctcttc cttctgccac 21541 tcacttatcc atgacgcttc tgtccactcg gtaagaatca gccacccgcc cgggcaaatc 21601 agctctttca gcttgctcat gtcggagctt tctatatctc ccgcagctaa taccacgtcg 21661 aacgagttcg gtgccagtcc ttttgcccga tactctcctt ctacaatatc catacttcta 21721 tactctgcat catagccttc caacgcttgc gggacatact ctgtcaacgc cccgttccct 21781 gtgccgactt gcaatacccg aagagatttg ggcgtatgct gtcgcgcaat gcgctgcaag 21841 agctcgccaa tgccctgatt gacctcgatg cccgtttctt cgccgatccc atctactagc 21901 atcgcgaatt ctgctcgttc cgcttcaagg tcccgatcca tcttgcgggc gctttccaca 21961 atccccagca aaacaggctc gtcactcgct ccatccagca cgacaccagc tgcggcgaca 22021 gcagggtgtt tgagcagggc cgattcaatt tcacctagct cgatccgatg ccctctgatt 22081 ttgacctgat tgtcttcgcg gccgataaac tcaatttcgc cccccggtgt gtagcggccc 22141 aagtcacccg ttcggtagag tctctctcca tcgatagggt gggagaagaa cctttcctcc 22201 gtgagccgtt gatctcccac atagccctcc gccaagccag ctccggtaat atacagatcc 22261 ccgatcaccc acaccgggca atcgcgcatc tgtgaatcga ggacgcggaa gccttgattg 22321 gcgagcggtc ggccatacgg aatactgttc cagtctggtt ccagtccgtt atacagatgg 22381 tagttcgacc agatcgatgc ttcggtggca ccgccgagac tgacaatctg tgcagaaggc 22441 agatattttt gcatccgatc aggcagggtc aacggaatcc agtcaccgga aagcaaggct 22501 agtcgcaggc tgtctacttt gacagttggc gtggaatcca aatacgtgac cagcatctgc 22561 atcagggccg gcacggaatt ccacacggta atgtcatggt cgactatcag ctcactccaa 22621 tgagacggat ctgtttgacg atcgggatga ggatacacga ccgcaccacc aacagagagc 22681 gtggcaaaaa tatcgtagac agataaatca aagctcagct gggcaagtcc aagcacgcgg 22741 tcactttccg tgatggcaaa acgtcgaagc atgtcctcga tcgtatttgc tgctgcacgg 22801 tggctgatga cgaccccttt gggctgtccc gtggagccag acgtatagat gatgtacgca 22861 ggcaaatccg ggtttaggtc aggcagtatc aatggttcat gctgcgggct cacttgatcc 22921 actgcaatcg tttgaatgga gtctgaccat tgcagctggc tggcagatac cgtcaaggca 22981 taacggatgt ccgcctgttc catcatggcc tgtcggcgca tctcgggttg tttcggatca 23041 atgggtacat agacggctcc ggcaaacaat gtaccgagta cggctgtgac ttgatgcgcg 23101 cctttatcca tcacgatggc aacgcggtct tgttcgcggc agcccagatc cttcagcttc 23161 cctgctactg ctgcagctcg tttcaccagt tctgcatagg aaatctgtcc ttcactgtca 23221 atcacggctg gacgatctgg cgtcgacatt gcttgcgtga cgattggctg atgcaaggcg 23281 tactctggta aagctgcggt ggttgcattc acctgctgac gctcttctcg ctgccagtct 23341 ggcaacgcaa tttcgtcagc tccctcccac acttgctcgc tgtccgccaa agattgcagt 23401 aattttgcaa aagtatcaaa catgtcgtca acgacatgct ccgggaaaac accctcccgc 23461 acatcccagt tcacctgcaa gccagcctgg ctgtccatgg cttggcaatc gatgaaaacc 23521 tgcggcgttt gactgattcc gtgcccagca attttgccct gtagctgacc gccctccgct 23581 ggttccacta acccaatcgc gctcgtaaat acgattggca tcagagcggc ttcacgaccg 23641 cgcctgcgcg ctagctcgcg catgacctcc acgccggaaa acaaacggtg atccaaatct 23701 tcaaacaact gcttttgaat cgttttcgcc cgtccctgaa aagaacgctc taatccccaa 23761 tcaaccgcaa gcaaattgac ggatgtgaaa tccccgacaa tctcatggac tcgctcatgc 23821 agcggctgtc tgttcagcaa cgtcaaattc aggcaaaacg cacgatttcg actccagcgc 23881 tcgatcacag cggcaaaggc tgtcatcacg gcggcggttg gcgtcaatcc tcgctgctgg 23941 gcacgctttt tgaaagcatc ccacgaagcg ttatgtaagc gaatgaagcg acggcgaaag 24001 cgtgcgcctc cattctgggt ctgctgtttc gccattggca ggtctggagc ctgtggcaat 24061 gcatcgatcc gttgctccca gtacgcttta tctctgccat acgtggtagt ctctcttagg 24121 cttcgttcgg caaatacgta atcgcgaaac gtaatcggca acgcaggcaa tgtttttccc 24181 ggttctttgt aaagggcctc aaactcaccc agcaagagcc aaatactcgc ccaatccgcg 24241 atgagaaatt ccatcgatac atggagtaca gccctgtcgc tcgttttcgt caagccgata 24301 tcaaacaacg gccatttggc tgtatcatac acgcgatgtc ccatcgcttc gcgtatgtca 24361 tcgagccttc ttcctgcctc ctgctcattc atgccactcg tatccgtata ggtaatcgtc 24421 caatgcggaa ccttctccag aatacgctgc tgaccattct gatcaatggt tgagcgcagc 24481 atgtcatgtc ttgcaatgag caggttccac gcatcctccg cccgtttcgg atcaagctcg 24541 ggatagtcca gctctatgta gatatggcac gccacgccac catagccaaa cagctcatac 24601 cgtcccagca aataagcaga ctgcacatcg gtcaggggaa aaggcataaa tcgcgctgct 24661 ggatctggaa ccaccgtcac cggttgggat tcggctcgca aaatggcgag aatgtctgct 24721 ttctgttctt tcaacgcctg taaatcgtcg gctgccagtg ttcctcttgg ggctctgtaa 24781 cgcaggctcc cgttttcctc ccataaaaaa attccatctc tgcgcaggcg catcaagagc 24841 tcaacgctat tcgtcttgag gttttggggc atatgcacac tctcctattt aaatgagctt 24901 ggccatttcg ttttcgtttt gggaaagctg ctgacgtacg ccagcatcga tgttgttctt 24961 gatgaggaac agcttttgtc caagtggtgc caatgggtga gactcctcag gcaagaccgc 25021 aagctcctgg actcctgccc gctgaaacac atcgagccac tgctggacag tcatgaaggt 25081 cgattgcgta tttttcctgt catctactgg cggagtcatc atgaaagctt gggagatgag 25141 catttcaacg aactctcgag ttggctcggt aataatcatc cagcctcctg gagcaagggt 25201 cttcaacagc ccttggatga cttcatccgt gtcccgcgcg ttgttcaaca tgcctgccgc 25261 aatcacgata tcgaagctgc cttctgagag accttgggca aacaaatctt tgtcgatatc 25321 aaccacctgg tatttcatcc acgggcaagc tttgtaccgt tcacgtgcag aggataagaa 25381 aaagtgggac acatccgtgt acacatactc cacattcagt cctttggaaa cagacggctt 25441 caggtggtcc actaccacat cactagtcgc tccagtcccg gcgcctacct ccaggatacg 25501 aagcgagttg gccgtagacg cgatccgcgc tactgcttct gcgaccgact tgttcaaata 25561 acgcgccaca agggtgtccc gataaagcgc attggcaaca tgcatgcgac cctcaggaaa 25621 tagcagcaaa gcagcttgct gggtatcatc catcagctgt ggcagccgat ccgcattgtc 25681 cttgagatag tccatgacaa gcggtgagcc cagcttgcca ttccaagcgt ttttggctaa 25741 ctcccaccgt cgttctactt cctctcgcgt catctgaatg tcgcattgat actcgccagc 25801 ggcatatttc aggaagccac gatccgtcaa gatgtgcagc cagcgcttga tgaccggatg 25861 atgacgttct gctacgtttg cagcagtgaa aatgtctgac gccgtatagg aatgttgttc 25921 tgctgtccat gctccttggg attgcagcgc aagcagcata gaggccaccg ctgctgcatc 25981 caggcgctca atgcacgtat ttacctgtac ggcatcgatc cctttcagct cgttctcggc 26041 agacgccgtg catgcaaaaa catcgttgtt ttccgccaaa gtcgcgtcat tgggtgatgc 26101 agtgtcgtgg aattcgtcgt ctggaatgct ccaggctgct tgttcgagag acgctaacga 26161 taacggctca tggctgccat gcgagcgcag cacgggatat cccaatgcct gcgtccattc 26221 ttgccactgt cgtgagcaca atagctcctg ctgcgcgcgc gtttccatcg cagccttatc 26281 gacttgcccc atgatcctct ctcgcataat gagtaaatcg cgtccaatag cttgcggcca 26341 ctgcttcgta agaatgtccc gataggtcgg cgtctcctgc ggtcccagta tgtgtgtact 26401 gttttccagc atgtgtgcgg gtggagacac tgtcagctca ccatgaatgt cgggaagatc 26461 cggtacatgc agacgcggct gccacacgac cggaccatgc gtgtctgtga gcgacaagct 26521 cccgccagct acgccaatcg tcacgcgatg cagcaaatgc agatagttgt ctggatcatc 26581 cggatcgact tcattgtggg cgcgcagcgt aatcgggatt ttgccaagct gtccgatcaa 26641 cacttgaaac ggcccctcat ccttgatgac atgactgatt ttccacggac gaatagaagg 26701 gagagcttcc tgcaaaatgt gcatgagcgg gaaggacacc tgtgtagcgc aagcagcctc 26761 gatgtacaag gcaggctgca cagccagcat cgttcgagcg caagcaataa agcggcgaac 26821 agcaggcaaa tgcacgtaga gatcgcccgt cataaaatga accccattct gcttggcatg 26881 ctttaggcac aatgccaaat ctttgtgatg gatcggctct tccgaaatga cgtgtatgcc 26941 cttggcaagc agctggatcg ccagctctgt tccattgccg cccatcacgg tggaacgcaa 27001 tacaacgcaa gccagatcaa tgtcagcagg taattgattc acatcggtgt acagcggaat 27061 gccatttcgc tcggcgcatt gacgcgagcg ttcacttcct tttgccaaga gccctaccaa 27121 ttcaaactgc tcaggcaatg cctttaccgc ttccaagtag aactgtccaa agcgggaacc 27181 gcataccacg gtacgcaact tacgattctt tgtcatacgt cacccctact tcatttccat 27241 gatggaatgc atgagttcga cctgctgctc gcgaagcgca tcaatcagac ctgtcgccga 27301 tacgccctct gccacgaaaa agcagcctgt ttttctgttc tgatcttccg cgatcaagtg 27361 agccactgtg gccgcgatga tgccagatat ccgattccag tcgcccgggt acagaagagt 27421 ggagaagacc cgcacttttt tgccgtcgcg ctttccggtc gcatgcaggt ggaacatcgt 27481 aaaatctttc gcacctggct tcttcgcctc aaactgttcc agcagcagct tggctgacgc 27541 ccttttttgt tcctcggtct tgtattgctg caaagccttg atcatcacaa attgattcag 27601 gatggcattg ctttggtagc tgttgtaaaa ataagcggat tcgattttat gctgcttggt 27661 catgaggccg aattccttgg tcactaccgg atacgtgtcg cgcttgcccg cgggatgtgg 27721 cagcgtgtag ttgcgatgga acggcccgtc tatttttttg agctcgcctt gcttgaagta 27781 agacattccc catccggtat cttcttcaat gctgcaaacg atgtcatagg ccgcattgag 27841 tgagaacccg ccctgtcctg caaaaaagac ttcgagcaaa tcgatttcct ctaaatcatt 27901 ctcagcgacg taagcgggga agacttccga cagccccggg taaacgccag cagagatgat 27961 aaacagcagt cccttttcct cgatttcctg ctttcgcgta agcaattgtc gatacaaatg 28021 ctcatctccg gacacatcta cgtaatgaac ctcatgtttg aggcatgcga cagcaacttt 28081 atcaacgatt tgcttggagg gccctgcaca attgatgacg agatcgactc ggccgcaaaa 28141 gtgatgcaac tcctcttcgt tgcatacatc cacctgctgg cattccaccc tgccgtccgt 28201 ccccgtaaaa agctcacgta gcttctcggg atttctgcct cccagcaaaa tcggatcgtt 28261 cgtcctagac aaaatcgttt gaaaggcagc ttggcctaca accccggtcg ctcccaaaat 28321 accaatcttt ttcatcccca acgttctctc cctcctggcc tgctccccgc ataattcttc 28381 caagaaaagg cggggctgcg cctgccactg agtcgcagcc cacctactca tctgcggttt 28441 ttctttattt aaatggtccc ctcgtcaaaa tcggctgcga gatcttccgt tgcctgtgtg 28501 ctcgtcttga tcagctcggc aagggtgcaa atcgtggaag cttcaaacaa gctttgcaga 28561 gacaaatcaa tctggtatct ctctcttaaa agattgaggc attggatcgc gcgcaatgag 28621 tctccacccc gcgaaaaaaa gctgtcgtgg atgccgattt ccgctacacc aagcacctct 28681 tcccagacct tggcgagctt gacctcgagc tcgttggaag gcgctacatg cgtctttttc 28741 ggcatgcttg cctttctttt gccaagcttt gtgattgcct ttcgatctac ttttccattg 28801 gcggatagcg gcagttcatc cagcagcacg tactcgcttg gcaccatgta gtcaggcaag 28861 ctatttcgca aggcttcgga caatttttcc ggctggaaca aacgaaccgc ctccggtgct 28921 tgcgccacaa tcagatggcg ctcgaacgcc tctgcgacct gagctttatc cggaatggca 28981 aggacgttgg tgaagccttg tgcttccagg cccgttcgcc attgctctac cgcaagcaga 29041 ggaagatgat tggctttgcg ctcatcctcc agatggctaa acccatcctc gaagaagccg 29101 acagtggtca gcagcagacg actgttgcgc gtcgactcga ccaggaacag aagcccccca 29161 ggtgcgagca gccctttcaa gtacgccagc gttttcccta tatcacgaga gcgatgcagc 29221 gtattgtccg caacaatgac gtcaaacgaa tgcggatcat agccttgtgc aagcggggaa 29281 acgttcatgt caagctgacc gtattccagc ggagcctgtt ctccccactc tttctttgcc 29341 ctgtcggtaa aaaaggagga ttcgtcgacg tataaataac gactgcgttc tgcaggcaag 29401 gtggacacca gcgtttgcgt caagctaccg gctctcgtgc caagctctag cacacgcaat 29461 gtcttgtctg acggatggtg acttacgata ctgccgaaca ccgccccggc aagactgctg 29521 taaaactccc gcgtcaggtc aaagcggctc aagcccgcag gtgtcaagaa ggcgtcgtct 29581 gctagaaaga gctccaacgg atcgagctca ccggttaaca gaccaataaa caacggatag 29641 tcgcggcgga aaacggcttc gagctcacgt gctgcttccg tccgtagcga ggaagctgac 29701 agaacatcat ccggcacccc ttcacgcaag gaacgcagac tgacgtactt acccgctgcg 29761 cgtttttcca gcaagccttc ttctaccagc acttccagcc aatgcgcaag caaggtctga 29821 taacgaggat gaatctgaaa acgatgcatg agctccgcaa ttgtagtgct ttctcctact 29881 tgcgcgaaca tccccatatg ctccagcgtg cggcataggt aggcggtgct tacacgatca 29941 gcttccatca ggaattgcgt gacggcttcc acatcgacac ttgcaggaat ggtatcggcc 30001 tgcgtatgac ctatgctgtt gatcgtctgc catcgagcag cacttgcagc gggatcggcc 30061 aactctgttt cgaataacgc ggaatccttt tcgcgatcca gcaccacata cccgaccaag 30121 cgcttttcat ccgcaccgtc atctggtacg gccacgacga cgtctttgat cccgtcatgg 30181 cgcttcagtg ccgtctcgat ctcgcccagc tcaatccgat gccctctgat tttcacctgg 30241 aaatcttccc gaccgagaaa ctccagcttg ccatctggca agtaacggcc caaatccccc 30301 gtgcggtaca gtcgttcacc tgtccgcgga tgcgtgataa atttttcatt cgtcttgttt 30361 tcatctcgcc agtagccttt ggcaagccca atgccactga taaacagctg gcccggcacc 30421 caaacagggc aatcccccat cgattcgttc agcacatggt aacgctgatt gaccattgga 30481 cgaccgtacg gaatactttt ccagctaggg tcaatctctt cgattgcgaa aaggtttgac 30541 cagatcgagg cttctgttgc cccgcccaaa ccgatcacct gaacgtgagg gaaaaacgac 30601 ttgatcttgt ctggcaaatc cagcggaatc caatcaccgc tcaacaagac gagacgcaac 30661 gattgcggca agtgaaggtt tctccccacg gcgtattcga tcagcatctg catcagcgcc 30721 ggaactgtgt tccacactgt cacctgctca gcttccagcc actccagcca gtgtgcaggg 30781 tctttggctt tatccgcatc cggcatgaca atcgttccac ccgcggcaag catgccgaaa 30841 atgtcataga ccgacaaatc gaaattcaaa ttggacaaag cgagcacccg atcttgtggc 30901 cccactgcaa agcgttgatt gatatcttca atcgtattga ctgcgcctcg atggtcgatc 30961 atgactcctt ttggcaagcc cgttgacccg gatgtataga tgacataggc caaatcctcc 31021 ggctgcccgg caactggtgt cactgcattc accgtgcttc cctcgtccct tgccgtcatc 31081 tggtccacaa tcagccgctc cacatccgca ggccagccca atcgctcatc cagccaagac 31141 tgtgtcagca cgaactgcac ttgcccatca tgcaaaagct gagagcgtcg ttcctctggg 31201 tgctgcggat cgatcggcaa ataagcggtc ccggatttca taatcccaag cgtggctgcg 31261 acctgctccc agcctttttc catcacgaca gcgaccaacg tattcggttc gactcctttt 31321 aaacgcagcc acctcgctat ttggtcagct gtgtcggcaa gctccccata ggtcaacgtc 31381 cgctgagtag agatcacggc aggctgatcc gtttggcatg cagcttgttt gtcaaataac 31441 ccgacgagtg tttctgtgga tagaggcgca gccgtatcgt ttgccgcgat tctttcttcc 31501 agtcgaggga cagcgatcag gctcggtgcc gcctcttgcc ataccgcatc ctcttctgtc 31561 agtcgatgca gcagctcgca ataggccgta aacatgtcag caaggagtcc ttctggaaac 31621 agtccttcta cggcatccca gatcaacagc agttctccgt cttgctcaac cacttgatgg 31681 tccagccata cctgcggcgt ctgcgtgatg ttgtaaacga gcttgcccag ccatttgcca 31741 tcggaatcag acccactcca ctgctccact cccaaggcgc tcgtaaagac aatcggcatg 31801 gcaacaccgc tatgctctcc tgtttgcttc gccaattcgc gctggacttg aaccccgccc 31861 acataaggat ggtccaaatc gcgccatagc tgctgctgca aattcctgcc tcgttccaaa 31921 atcgtctcgc cagcggacaa ttcgactgcc agcaaggtta acgtagtgaa gtcccccacg 31981 atttcgccta cctgcgcgtg caagggcagg cgattgaatt gcgtcaggtt gatcgtaaaa 32041 cgcgagctct tgctccatgc accgagggtt tccgcatacg cggtcagcag tatcccggaa 32101 ggcgtcaaac cgacctctgc tgtccgcttt ttcagccgct gccatgcttg gcgattgatt 32161 ctggcttcca aacgatggaa gcgctgctcg gtaatcgtgt caggattttt cgccaaaggc 32221 agctgtggtg ctggcggcaa atccggcagt cgatccatcc aatagtccag atcgcgttgg 32281 tacagctctg tagatttgag cgcttcttgg gccaggacat aatcgcggaa gcttagatcc 32341 agtggtggca aaggcgcatc cggctcatga tacagcctcg tccactcgct caagaggtgg 32401 aacatgctcc atccgtcaaa aatcaggttg tcaaagctga tatgcaagcg aacccgttcg 32461 tctccaaagc gggaagcgcg cacatcaaac agcggccaca catccgtaga cagcacctga 32521 tgggacatct cttcccgaat cgcttgcagc tcggactcag cttcttcagc cgattggttc 32581 cgcaaatcca tgacctcgat ccggtaagca ggaacctgct ccaaaatctg ctgacgccag 32641 ccatccggca aaatcacggc ccgcatcatt tcatggtggt caattaatcg ttgccaagct 32701 cgattgatcc gctccaggtc caagtactgt ccttcaattt cgaaatagca atgcgtggag 32761 acatgaccca aggcgtaaac accactgcgc ccgacccagt aggcttgctg gatatccgtt 32821 agcgggaaag gctgatgcct gtcttgtgga gccagtacaa tggctggcaa gcctgacgct 32881 tctccttttt cctccagaag catctccaca tgctgggcaa gtccggcaat cgtcggcttt 32941 tcaaaaatgc gccctaacga cagctctacc gcaagcttgc tgcgaaccat cgcactgagt 33001 ctggttgcca atagcgaatc cccgccgagc tcgaagtagt tgtctgtaac gcctacccgt 33061 tccacttcaa atagctggca ccaaatagcc gcaagtgctg tttcgattgg tgtcgttgga 33121 gctgtatacg ctttttctgt tttggccttc atcaggctgt caggagtcgg cagggcttgc 33181 cgatctacct tgccgtttgc agaaagcggc agttcattca acaatagaaa agcagtcgga 33241 accatgtaat caggcagctt ttgactcagg aagccagata gttttgctgc gttgaagcgc 33301 ttggcctgaa gtggcgcctg cgcaaccagt acatgctgac caaaatcgtt ctgttccggg 33361 aaagctgcca cttgtgcgaa ggcttgctgc tgcaaggcct gctgccatgc ttccaccgat 33421 aacaaggggc gttgttcatt acgccgctca tcttcaaaat gcgtaaagcc atcttcgaga 33481 aatgccgtgc tgatttgctg caatcggctg ttgcgggtca tctccagcaa aatcagcatg 33541 cctcccggag acaaaaggct ttgcacatac gagagagcca tcccgatgtt tttcgcacga 33601 tgcagggaat cagaggcgat aacaacgtcg aactgatggg cttcaaagcc ttgagatcgt 33661 ggactttgat tgatatcgag cagttgatag tgcacaaacg ggtactcccg aaaccgcgtt 33721 tttgctgcat tcgtaaagaa agtcgaggtg tctgtgcatg taaaatgtgt cgcatctgcc 33781 ggaagcacag ccagcaatga ttccgtcagt gctaggctcc tcgccccgat ttccagcaca 33841 cgtatcggtt ctgattcaga cctttttcca agacgatgga tcagcctttc gaccaacgcc 33901 agtgccgcgc tgtctcgatg ctttgcgcca gggagtgtct gcatcagatc attcggagtc 33961 agattggatt cctccgagaa gaaatgggcc aacgggtcaa gctcgccacg caaaagcgca 34021 acactctcgt cattgacttt ttccaagtaa cgcaaaaggg cttgtgcttg atgttcccat 34081 gcaggcaata cgtgagagac gtgcggcttt tccagccatt cagtcaggct cgcctgcgtg 34141 atgctgtaca catccgattt gtctttacgg acaaagcctt cgtcctccaa tgtttgaagc 34201 cactgtctga ccagcccgcg ataacgctct tgaatcccgc agttctgcat caaatcatcg 34261 agggagtagt tggcattttg ttcaaagttc actcccgcca tctccaatgt gcggtaaatg 34321 aatcgaacag caagtttctc catatacgcc caaatcgagg tgaaatcttc cggtctaatg 34381 cttgcaaaat gctctgacaa ggtctgcaca cgacctgtat cgacgacatc tgcccacagt 34441 tcttcgctct ttttcggatc agcctctaga cgatcgaaca gcgctgattc gctttcccgt 34501 tctggcacca catacccaac cagctgcctg ttctcgcgcg gatcacctac tgccgtcact 34561 accgcatcac gaatccccgg atgctgcttc atggccgatt cgatttcacc cagctcgatg 34621 cgatgccccc tgattttcac ctgaaagtcc ttgcgcccga gaaattcaat ggtcccatcc 34681 ggccaataac gcccgagatc accagtccga taccagcgcg aaccgttcca gttgacaaag 34741 cgttctgcgg ttagggcagg atcaccccga tagcctactg ccacacctgc tccgccgatc 34801 cacaattctc cctctaccca gtcagggcaa tcacgtccat gcgcatcgac aacccgataa 34861 gcctgattcg cgagcggtcg accatacgga atcgatgtcc agtgagcggg caacggcagc 34921 gtcacatcaa aaaagttgga ccagatcgac gcttctgtcg ctccccccat cgccacaagc 34981 tggctgttcg gtgcgagctg gttcaatcgt tgcggcaaat cgaggccgat ccagtccccg 35041 gaaagcatgg tcaagcgaag cggcaagctc tcgtacggcc cgctctccgc agcaattaag 35101 agcatatcga gcagcacggg cacagagttc cacagcgtca cttggtgctg gtccaccagt 35161 ctcgcccaat aagccgcatc ccgtcgcact tcttccccta taagtacaat cgagccgcct 35221 acactgagca atccgaacag gtcgtagaca gacaggtcaa aatcaagcga ggaaaccgcc 35281 aaaatccgat ccgtttgccc gattccgtag cgtctgttta tttctgcaat ggtgttccat 35341 gccccggaat gattgatttc tacccctttt ggttcacctg tggagccaga agtaaagatg 35401 atgtaggcaa gactgtcaaa agaaatcggc acgggttcag caagcggcga gacattcaac 35461 gcatctgtaa cagacagaac aacagcgtct tttggccact ccagtgtttg cgcctgctcc 35521 gtatccgtaa gcacatagcg aatctccgct ttttgatgaa tgcgctcacg ccttgtagat 35581 ggctgcccca ttccaatcgg gacgtagcaa gctcctcttg ccacgatacc gagaaccgca 35641 gcgacctgat cgattccacg cggcaggctg atcgccacag ggtctcctgc ttcaacgcct 35701 tgcttttgga gatacgccgc aatctgcaac gcgtacgtcg ctaactcgcc atatgaaaaa 35761 gtagtggacg catgactatc gattaatgcc agctcgtgcg gattctcttt tgcataggca 35821 aaaaaggcac tgtgcaagca atgactcgat tgcggttgtg aatcgtctac agcctgatgg 35881 ttcctcttct gttccaaatc gggaagcagc acggatggtg cttgccagtc attgtcctcc 35941 gtcaccaagg agtccatcag ctggcaaaaa gcgccgaaca tttggtcaag catcccgtca 36001 ggaaacagct gatcaaccgc atcccacgcc agcagaagcc cgccgtccat ttcatacgac 36061 tggaaatcga gccatacttg cggcgtttgt gaaatcatgt aagagagctt gcccaatgtg 36121 tcccggcatt cgtcattgat cagcggcgta cccaaattgc acgcgaacac cacaggggca 36181 aaatcccgct ctccttgacg gacacgagcc atatcccgct gcagctgaac cccggaataa 36241 gccgcatgtg ctacatcctg atgaaactgt gattggacag attgcacccg cgccaggaag 36301 gaagatggct cccgcatgtc aaccgcaagc agcagcaggt tggtaaaatc ggcaacgacg 36361 tcttcgatgc cagcgtctcc ggtttggcga tcaaatagcg gaatattgat gagaaactgc 36421 gaatgggtgc tccaacgatc cagtacttct gcataagccg tcaacagtac cattgctggt 36481 gtgacccgct gagctgcgga tcgtttttgc aaaagagccc attcggccgg cttcatgaaa 36541 tgcgtccgtc gcgtaaaaac aggcgacttg atcatttccg gcttttcctt cagtggcaag 36601 cctggcgctc ccggcaatgt ggataggcgt tcctgccaat aacgggcagc ttcctgtctg 36661 tcctgtgccc gacgctctgc ctcttgcccg agataatggg caaagctcca attggtcggg 36721 gcaagaggct tgctgtctcg tgcataggct gccgccaagt cgcgcaatac gatgtgcaga 36781 ctctgtacgt cagcgaccag caaatccaga tcaaaatgga tgcgggtgcg tccttctggc 36841 aacaagctca gctctaaacc ggctacttct ccggcttcca ccgccaaacg acgatgagac 36901 agccgctccc gtataccgtc tagctcccgc accaattcgt cctcagaaaa agaccgcaga 36961 tcatggacag gtacggcagt ggacctcggg gcactcatca cctcttgctg tccatccgcc 37021 aaaaatctgg cccgcagcat cgggtgatgc atcagcagtt tgccccacgc tgtttccaat 37081 cgatccggct ccacgcccgc cccatcaatt tccaagtacg catggcaccc gactcctccg 37141 agaggctgat catcctggcg tccaatccag taagcgtatt gcacatcggt gagtggaaag 37201 ggcacattca cctctacttc cacatcagtt ttcctttcgt ccacatgtgg aagcgacggg 37261 ctgctttttt gcagcaacgc ctgccaatca cgcaaggtag gagcaccgat cagctcggca 37321 aatgtaacct ttgcgccttc cttgcgccat ttgttgacca tcctcatcat ttgcaaggaa 37381 tccagcccca gctcgatcag gttttgatca tctgaaaatg cgacaggcgc gggcaacaac 37441 gcctgaattt gcctcttcat ttcctcatag ctcaaggaag cggcgggact tgcggtcaga 37501 ctgtcattga gcattttgga catccttgtt ccctcctctc tcgtgcaagc ccctattctt 37561 ttccaatcag ctgcctggag aagctgctca gcttttcacg cgtttcttcc agttctctgg 37621 acggcaaaga catttcgacg acaccagctc cggcatgcag ccaagcctgg ttgtcctttt 37681 gataaatcgt tcgtagcacg agagccgcat ccatggcacc gtcgctgtca aaagtcatga 37741 cgcacccgct gtacagacct cgtggcacat tctccaatct gccaatcgcc tcgatcgatt 37801 ctcttttcgg gattcccgaa gcggtaacag ccgggaacaa cgcgcggaag gcatcccatg 37861 aattgcattc ttgtttcagc ttccctttca agcgagaagc gatatgctga accgttcctc 37921 ggctagctac tgacataaaa tcgttcaaga cgatacttgt tgaatcgcaa acgcttttca 37981 gctcttcgaa tgccagcttg acggaaacag cgtgctcggc aatttccttc gggtcattca 38041 gcagctcttc cttgagcctg ctggcctctt cttcactgct gccttttgcc cgtgttcccg 38101 cgagtgggaa ggtactcacc catccgtcgc tatcaacttc tacaactgtc tccggactaa 38161 aaccagctgc accgagaccg tccaaactaa caaggaaaga gcgtgctggc gtattcactc 38221 gtctgccagc aatatagctc gcaaccagat ccagctcgtg atcaagcgga atttttctcg 38281 acaagatgac cttgtggtat ttgtgttcct gaatctcgcg taccgcttcg gccacgtttt 38341 gcatgtaggc ttccgcgtcg tatgtatcgg tttgcgggac ggacagcttt ggcttgtcca 38401 ctctttgggt cagctgttgc tcggcgtgcg tattcatcga cagctcccga agcagttggc 38461 taaattcgct ccgcttctct tcacgcaagg ctctcaatag gaccgtgcct ttgttgaagc 38521 gcagctcgac ctcaggaaca aacagcttga gcaagcaacc ctcttctggc atgagcggca 38581 agccttgata ataacgcgcc atgccaaaat ggacggttcc ataagcgcgc cagttttgaa 38641 tcggcacctg tgccatcgct ttttcgagcg tctcactcag ctcgttgttg tcgaaacgga 38701 gagtctcgtt gcgataagtc aaagtagtct gcgcaccatc cacgtagaga agcgcatgaa 38761 tccccattcc tagtgacagc tcatctccgt tttcatagag caggtagttt tcatacccgc 38821 tgcgctctgc aatcagtgcc gctgccatat gcgcatcacc cgcaaaagca aacgtctctt 38881 ccaaataagc gatttccgct ggcttcgtct ctgatttcgg cgctaacgcc agttctttca 38941 gcttggcttt attgactttt ccgacgctgg ttagcggcca gtaatcgatg cgttcgattt 39001 ggtctggcat tttgtagcgt gccactcctt tttcctggaa gaaggcatgg acgtccgcca 39061 agctgatcgt ctcgtcgtcg gtgatcaaaa atgcgcagct tttctcgccc agcactggat 39121 cgggaagtgt aatcagcgcc gcgtctttaa tggctgggtg catgcgcagg tacgtctcta 39181 cttcagccgg catgattttt tcgcccgctc ggttgatttg ctctttgatc cgtccaccga 39241 tttgaatatt tccttctggc gtgattctcg ccttgtcccc agagcgatag aatccatcgg 39301 gcgtaaagct ctcgcggttt tgttcctccg ctctgtagta gccgcgaatc gtatacggtc 39361 cccgcacaat tagctctccg tattcgcctg gcgcgacatc gtttccatgc tcatccacga 39421 ttcgcacttc atcgccctcg gaaatcggac gcccctggca gctggtaatg atcgactcag 39481 gatcatccag tgatgtgcag cagatgagcc cctcggccat accgaaaact tgctggagct 39541 tgcatttcca ttctcgcgtg atgcggctgg cgagattatc atccagcatg gagcctccca 39601 cctgaagaac ctcgagactc gacaggtcgc tttctgtatc ccattccagc acttcctgcc 39661 atacttgcac gatcgaaggc acgaggccgg taatggtcac gcgttctttc tcaatcagcg 39721 gaaaagcttc gtcgcagctg gtagttttac atagtacgat cttgccgcca acggacagtg 39781 tgcctaagat gcctgggcag cacagaggga aattatgcgc aatcggcaaa actgcgagat 39841 agacgcttcg ctctgtcagt tggcaacggg ctgcggttgc ttttgcattg tagacgtaat 39901 ctgtgtgtgt tctcggaatc aacttgggta tccctgtcgt accgccagac aacagcaata 39961 acgcagtgtc tttgtacgaa ggggcttcca gctcgattgg cggtccgctt atctcagcca 40021 agttcctccc gatcgaactg tccccatccg tcatgacgaa tttaaccgac gtatgccttt 40081 tgactaaatc ttctgccatc ttcgtgtaat caaaaccgag aaacgtcgtt ggaaggatgt 40141 aggcaacagg cctcgcaagt gcaaaaatcc cgtccaattc agcctctctg tgggcaggca 40201 atacgagaat cggcacagcc ccgatgcgaa acagggcaaa gcaagtcagt acgaaagaaa 40261 ttcgattcgg aagctggacg gctacattgt cgcctttttg aattcccatg tgataaaaac 40321 cggaagcaag cgcatccacc ttgctgtcga gctcgctata agtgagcctc tcctcgtcct 40381 ccaccagcgc ttctttgttc tggtactgtt ccgcccattt gcgcaattgc tgcccaattg 40441 tcagcggctc ccaaaaacca cgctgttcat aagctattgc agcttgctca taccactccg 40501 tacttactct cattccgtcc tcctcctgtg taactgcggg tcactctttg cgcccgaagc 40561 cggatcatgc agagactgcc ttgtcgttgt acgcatcatg ttggtttgtc taacaacaag 40621 atattgatag tgattctcat tgtcaatttc atcttcaagc tgttttttct acatttggga 40681 aaaacagggt agattatctt ccgttttctc acgatttctt cgtttctcac gatgagattt 40741 ccatattctt acacacttat atactctcat taaacccgat aaagtttatc agtataatag 40801 aagattctcg tttcaagtac tccgatttac ggtcttccta tcccgattgc aactgctcct 40861 gcatagcctc tggcaggcgt aaacccgtaa actttccact ccccgctcct gatcccatct 40921 ccgtttaccg tgaagctgcc atcttgtttt tccatgaaaa atgaatcgag agggcgaatt 40981 aggccctccc ctgtcgcttt gacaaaagcc tccttgcgtg tccagcaatc aaaaaaagcc 41041 tgctgtcgct catcaaaggg taaacgcaag atcctctctc gctccacagg atgaaagtag 41101 ctcatgagct gttccatttc cgggatgtga cgcaaatgct ccacgtcaac gccgagaagg 41161 cgatcgcgtg aaaaagcgac cgccacaagc tcatgcgaat gcgacagatt gaaaaaaagt 41221 gcttcggaat cactgtctgc tccacataaa agcggtttcc cgttcgaatt gcactcccat 41281 tgaaccgcgc gaggagaaat cccttggtac agtccagtca tctttctcag cagtccatgt 41341 gcgacaacat agcgttccct gtctgcgtgg aaatgaaatc gtgcccgttt atcgagttct 41401 tcggcagaca gatcgccttc cagctcctgc atacggtgtt cccatgcttg cacaaacgtc 41461 agccaaatat gcacttcccc tttagccaac aacatagagg acgattcctc cagagctgat 41521 tttgtcctct cagacaaatg ggttattcgc acctgctgca tatgctgcat cccattagcg 41581 ctcccctttt cctgctaccg cactccggta ttgtccgatc attttggtta cagattgcag 41641 gagaacctct ttgttcgtcg tcaggaaaaa atgtccgccg tctaccattt caaacgtaaa 41701 tccggcactt gtatgactag cccaagcctc catttcttcc tgcgtggctt cctgatcctc 41761 tgtcccgcaa tacgcagcaa ttgggcaatc caacggaggc tcctcggcat acacataggt 41821 ttcgtcgagg gtaaagtccc cacgcaacaa cggcatgaac aactgcatga gctccttgct 41881 ttgcaggatc gcctctgggg tcccggaaaa gcgtcgcagt gctgcgacaa attcatcatc 41941 aggcaaatgg taaataggct tcggttccgg gaagtgtgga gctcgtcctc ctgaaacgat 42001 gaggccaagc ggaagacgtc cccatttgct ctgtacggca cgtgccagct caaaggcaat 42061 tcgcgttccc atactgtgac cgaaaaatag aaacgggcga tccaaatacg gatgaatcac 42121 ttgggccagc tcttccacca gctctcccat atctgagtac gctcgctcgg caattctatt 42181 ttccctccct ggcagctgaa ccgggtaaac accgacatca ctgggaaaag cctgtgccca 42241 tcccctgtaa atcgaggccc ctccccctgc gtaaggaaaa caaaacaggc ggacgctgtc 42301 tttagcttgc ggctgagtaa gcagccatga tttcgctatc gtatccatgc tcatatgtac 42361 tcctccattt cgtctcttgc tgaaacgctt tgatacaacg tacatgataa tgattctcat 42421 gtaccattgc caaatacata caatcccctc cttttccgtt ttctggtaca tttccgcgat 42481 tatccctgat tatctcgtcc tacgttcacc agaatgatta ttttgcaaat cctccaacct 42541 gtaatatttt ggcgattgtt caagaaaaac gggaaaacac ggagataata ggcgaaaaag 42601 ctcgaaaaat atcccaaaat attgaaattt gggctttttt tattttgaca acgattctca 42661 ttatcaatat tgtgttctta tactgacaac cgtgtgtaca actagcaacc tgttttccag 42721 cattcctgca aaagggggat cgcaagtaga gagtgtgagt caagcagatc ggctacttat 42781 gtctgaggga ggatgttaca tgcaagccca aacatcatta gctgcccaaa gcggcagatg 42841 gaccatgcgg gatatgatta cgctcgcgat ctttaacgtc gtcatgctga tactgatgac 42901 gattgccccg attattaccg ttgtttctca tttactggtt ggcggcttta ccgcgctact 42961 caacggtccg atttatatgg tcatgtccaa taaaatcgcc aagcccggga ccctattttt 43021 tacagctgtc ttgactggat tgtattttgt cggttttggc tacgcgaatt acttacttac 43081 cttagcggtt atcggactca tctgcgaact gatcctatgg ggaaaaggct cttatctgaa 43141 tcctgtgcgc aatgcgatca gctattctgt tttttatgtc ggctattcgc tttgcggggt 43201 tgtcccgctt attttcttcc gcgaatcgta tcttgcgacc ttggaaaaaa gctatacacc 43261 cgagcagctt tctgcgatgc tctattactt tgaaaccccc agcatgattc tcatcatgtg 43321 ctcgatttca tttgtcggtg gattgctcgg ctgctatttc ggcaatctgt tgatgaaaaa 43381 gcacgtcaaa aaggcaaagc tggtgtaatg ctctgcgtaa aaaaaggcat attcctcctc 43441 gatgattcga gttggaatat gcctgatcga tgtcttagca tcgtccctta ttgcccttcc 43501 atggcgagta aaataaacgt gataattgcg atgatcgtac caaagacgaa gtataaaccc 43561 aaaagaatgg ccattaacaa caaggtagct tttgaccagt ttttacgatt cagattccca 43621 tctgaaccaa aagcccacat aaataacaat acaatattcg cgatcggaat catcatgaac 43681 aacgagacga gtatccaatc tttcattgtc atgacctttt cgttttccgc tatgcttcct 43741 tccacatacg tttggtgatc cattctacac cctccacgtt ttttgcctat atcaccgttt 43801 ccctattgtt caaccgctgc tccaatgaat gccaacatca gaattaaaaa gaagacgctc 43861 aagtacaacc cgatgcaaac acctatgatc agcaagttcg cttttgccca gttctttctg 43921 tttagattgc cttcactgcc aaatgcccaa acaaaataca tcacgagatt gaccacgggc 43981 accatcataa ttaaaaaagt aatcaaccat tctttgaccg acatgacccg ctcattttca 44041 ggcacgttca cttgccattg ctcttgatgt tgctgctgtt ccaattcgaa acctccctgt 44101 tctgtcatga tcatttttat tatattgtgt acttttaaaa taatccttac ggcaacaact 44161 tattgctatg tcccccgttc atctcttaat tttttccagt atatcatttt ttcttttgcg 44221 ctacgtcgca attctcccat gtaagagtaa aaatcggtcc aggactgcca aatcccccaa 44281 ttaaacaatc aaccaacgag tttatcttaa aaccatatat gctaccattt ataggaacat 44341 agaggaatga attgagatca agcaagggag agaagccaga tgaacataaa gaaaaatcaa 44401 gtatttgtag aactggaagt agcgaattgg gacaacacag acctttcatc ctcgttaatt 44461 gaaatctgct actctcagaa ggagtatgaa aacgatctaa tcgaggttca tcaagttgtg 44521 gacttgggaa agcataaagg caattcaaaa tacttaatta tcattaatat tacgcgtgac 44581 ctggataatc tcggagatga tctggataac ccttatatcg tcaaaggccc ttgaaatttt 44641 gttttcaagg gcttttccat ttactcatat cggcttcctg caattaaaat ggtagcaaac 44701 aaattccagt ctacaccttc aagatcagct aacatattat cacaatcctc aatccatgac 44761 tccatcccac taaggaactc ttcaagtgat atattcgccc actctttttt attttgctga 44821 taatccttaa ccaaatgaga aatgaattga accatatcct ctctactctc aaccgtaccc 44881 gctctctcta gaatatccat gcgaaactcc tcctccccct atgtctttat cttccatttt 44941 agtatagatg gttcaaagga gtttgacgaa ttggggaatg aaaaaagccc gctgacgtgc 45001 aacgggcttt tctgtctctt atgtgagggg gaacatctgt ctagttaata acaggattcg 45061 ggctgtcact attctcgtag acgttcctta ttgaataatc tcggaaatcg cttgcttttg 45121 ctccaaaatc tcgctttgta cctggattag ttctttcaac agatcagcag cctcttgcaa 45181 ggatgcagct gcttgctcct tatctccggc ctggaatgct tccttcgctt ctttcactgt 45241 gttctgctca tttgttttca gctctttcgc ctgctctttg ttcgctttct tttctgtgcg 45301 aattggcttc aattcttggt tcatctcttt gaaggacgct tttttctctt tgacttgggc 45361 caattctgtt tggatatgcg ccagtttttc ttcgatggcg gtatggtttg cggcgatttc 45421 agctttaatg ctcgctacct tttccttatc cttagctttc ttcgcttctt tcagttcagc 45481 agacagcgat ttgtttgctt cgcgcagtgg cttcgtttct tccagtgcac tttttacctg 45541 ttcgcgcact tctctcgtca catcgcccca aagaacatcc catgcctgtt ggttgatttg 45601 cgattgtgct ttcagtttat cttgcagagc tttttgctcc atttgcaatg tttttagcgc 45661 ttgaacttca ggcaggcttt tccaccctgc tactttccct tctttctcag ccgcaaaagc 45721 tcctacggca ctcgttacca gcaagctcgc tgcgactaca gatacggaaa gcattttttt 45781 catgtgtgaa cactccctgt ctcctattgt ttcttacaaa caaatcgtac cgtacgagcg 45841 tcgggaatgt tcgggataac ctcgtgaaaa gtaaggggaa agtgtgggat ttgggaaaaa 45901 cacaaaaaac caggaaaagc ctgggtcgat ctgattgcca ctcattgaaa actatttggt 45961 ggggcagtta ggactctaat cgttcgattt cattttcaaa acaacaatat ttccagcgtt 46021 tccaaaacaa gaagcatggt acaatccttc caaaatatgc tctttatgaa attccccaac 46081 aaatatgcga tcttcattct tttgatcatt agcgtatcga acaaggatta ctgtggcatt 46141 ctgcacatgc ttgttttgca tgaacaattg aatattgcgg ctgaaactta gaatatcaac 46201 tggtacttcc tctcttacca accactcgtc aaactcccca atgaattctt gattcactat 46261 ttcaaaaacg cttgaatgaa gaaaatgtct caaatgctct aacttattgg gcaaaatttc 46321 atctttcggt aacactttaa aatgattggt aacttcaaat tctttcaaag atgcagcaac 46381 atcagcttca ttatcggaat caaatgaaat gaactgtgta caatcaaagg ttacgtatga 46441 catagcctca cctcatactg ctcgattaaa ataatgaaaa gtttacgcta ttcttcatga 46501 ttttatctaa aaactgatca aacgaagatg caatatgttc aacttcttca aattcaggtt 46561 cagaaccgca tacgattgaa ccaaattcat tcccgagatc tattgcataa taggtataac 46621 catttcttac agataaagct atgggcaaat aattctttat tggttagatg gttaatactt 46681 tcgtcaacag ccgttcaaaa aatgaaacct tgaaaggcaa gcagccaatc aaggttctgg 46741 atatttccac tcaaaactat agagtacccc ttcattttgg acaagaatat ctaatcctaa 46801 tcccattcat taagtggaaa ttttagtaac tcattgctgc attttgggca ttcttgtttc 46861 gaaaaatccc ttgtccaaat cctacaataa atacaccttt tgccgtataa ttccgggtgt 46921 tgtttattgt cctcatccgc ttctggttcc agtatagcaa atactttttg tctggttttt 46981 tcatataaat gactaacttc aggagaaata tcatacgaat cagttgttgg ttcccattca 47041 cacccctcta ttatttgtac cggtctatcc aaatcttctt ctaatctatc aaaggatgtt 47101 ctaggccatt catcagtatg aaaaatatct ttctcaattt tgtaccaatc ttcccaactg 47161 gatatatttt ctaaatgact atttaatttg tttgtatcaa tattaatatt gaacattata 47221 ttcacctacc ttggtgttgg tggtttctta gttttttcaa atacatacta cgcttcggtc 47281 gctacaattt cctctagttc cacaagaacc taggtcaggt tagcgttttg gtcgaccaca 47341 taccgtgtcc gtcttccgcc ccaagtcatc gaagtgtgca cgtatttggc atcataggtg 47401 tctcactttc ctatcaattg cccaattgcc tatcagttgt aacacaaacc tatggctgga 47461 aggtgcaaaa aaaggctcat tcctcctcat tgttcaagtg gaataagcct tataaagatg 47521 gtctaaggat gtaaccttat tagtgttaac atagaatatt aataagataa ttctgcctta 47581 caaatcctct gatttttccc acacattatc aggatacggc catttccata agtcgataaa 47641 caaccctatt ttttttattt catttattgc ttcctcacaa atgatcgcac taccaatatc 47701 catataaaaa tcgtatgcga agttcacaaa aaacttatcg ttattcctta attgacaaac 47761 gatatcttcc ctcattccta atctaacgat atggtcaata tggtttccag ttaaaatatc 47821 gccatcattt agagagtaat aaaactcgat gatactgggg ggataacagt caggataaag 47881 gttaatgtta tctaaaaata gttcttcctt tagtttatta attatatata cctctaagtc 47941 tttaacttga agaacattca tatacgccaa gacggcagca acatatttat cttctactct 48001 taaatattct gacattgtga gtgggccgtc ttcataaatt ttgccaatat caattattga 48061 agtccaagta gatatcttcg gcttatcttt ttcgctttct aatagtggag gatattttct 48121 aacttgccag taatacattt gattaatctc caatcctgtc caagtttttg tcatatgttc 48181 ccatcctcgt ttttctactc attaaggatt cgattgattc tcccattttc catacgccac 48241 cattatctgt tctacctgta ctttctcttg gaatatctct agtaatataa actctacgtt 48301 cttttgagta gaaaactgct gctttggctc ttcccgcgtt aactttttcg aagcctaaca 48361 tcttcgccgc ttcttctgct tgtttatctg ttctgtatgg cgcttctggt attttagttt 48421 tcttagaagg tgcccatttt ccagtcttat tcttataatc attgattctt tgttgctttc 48481 ttccgtagta tccgccatgc gcaatttcgt catgcctttg tgaaatattc gggagttttg 48541 aagtctctct ccttaaattg gattataaaa aatatcaaaa agcgacaagt aactaaatca 48601 cctgtcgctt tttcgactat ttcaaaaacg tgttcacttt ggttaattat aactttttta 48661 tagtaattct ttttaattgg tgtaaagcat tctttttaat ttctttttcc tttgatttac 48721 ttaagagttc taatttcact ttagactctg gcgtatttat atcacctaga gcccaaatac 48781 attttacggc aagggcattt gtgtaatgaa gatactcaaa ttttgttatt gctgctttat 48841 aaagactttc taccgatgaa tttgattgaa agtattgaag caagccagca atatcctcat 48901 gtgtcttatg ccaagcttca gtaattaact ggtttaacat ttccaaatgt ctttcatcaa 48961 acaaatcaaa tgtaaatcct atataaaata gtaatcctaa gtcatcttta tttttttctc 49021 tacaaatatc ttctaatagt ttgtcaaagt agctcgttat ttctatattt cccttgaaca 49081 aatccaaaaa ttctaaatct gttattccac cgccaataag ttttttgatt agaattctta 49141 gttcttgatt catttttata tcctttcaaa actagtaata ttatcattaa aaatatccaa 49201 tgcagttcct tttcctaggc ctatatttac ttggggtttt cctattcctt ttttaccaga 49261 gagaccctcc cctttaaagt gcgcatattt ctcattccat ttagagacac tactgatatc 49321 tttcatttct ggatacctag catttgtaat tggagaatcg tttttcaaac ctatttcctc 49381 taattttgct gtagtgccag gtttaagttc aaaccttact agtactcctt cgtactgtgc 49441 tgcatattcc ttggtaggtg aaataaaagt ttcacctgta ccaggcattc tttttgtttt 49501 ttccaatctt ttataatgtt tttcggacat tgttctataa tatacttctg attcaacttc 49561 acctgtctcc tctttacact tcatcaaccc caacggatca atgaacccaa tcggatcccc 49621 attcacataa gcaaaacggt taaacgtctg cccgtccgtc atatcccctt ggagcacatc 49681 tcggttcagg aaccgcttca atcccggatg gtaataccgc gcccgcatgt agtacaaccc 49741 attcggatcg gtcatgactc catctcggcc gttatagcaa aacggctgtt tcgtcctgcc 49801 ttcatgtgct tccagttccc catacaatcc gtaggtataa cggtcagtga ctcgaccatg 49861 ctcgtcggtc aacagggtcg tgctgcctcg cgtatccgcg tgataggaca aataatcgcc 49921 ttgggcatcc tcgcgaccaa taagccccaa tccatataca taatacgctt tggccgctcc 49981 attttcctcc agctccataa gaacctgagt caggtcagcg ttttgatcaa ccacataccg 50041 tgtcgtcttt ccattccaag tcatcgaggt acggacgtat tcggcatcat aggtgtagcg 50101 agcttgtccg gcacgaacaa gacgattgcg ggcatcatac gcatacgttt ctggctgttg 50161 cttgcccggg agcagcagaa gattaccgtc ctcgtcatac tgaacctgtt gaccatctac 50221 ggtgtccagt cggttgtcct tggcgtacgt catcgccgta gcaagactcg aacctgaatc 50281 cccaatagcg gtaatattcc cgccctggtc ataggtgtag agaatctttc gtcctgccat 50341 ggctccgctc gtcaggcgcc gcagagcatc ataggtgtac tgcttttctt cctcttggat 50401 gatctgcccg agctcgttgt acacaaaccg atattgctgg agcatgacgc cttgcgcatt 50461 ctgatcccaa agacgcagaa gctgaccagc tgcgtcatag tgacgctgct ctaccgtgcc 50521 gttcggtcgc tctgtacgaa tgaggcggta attttcatcg tacgtgtacc ttgtgacacg 50581 acctgcccag tctgtgaccg tggtcaattg acctgcgaga tcgtaggtat agcgaaccgt 50641 cttgccatct ggatagatga gcgtttccag tctgcctccc gcatcgtagg tgtactggag 50701 cgtattccca tactgatcgg tgctggaggc gattcgcccc aaaagatcgt aggtacggcg 50761 cttggtgtct tttccatctt ctttgacact taccacgcga ccctcggcgt cgaaagtcct 50821 gcgaacagtc cccgcttcgt cttgctgctc aatgagctgt ccggctgcat cgtagcggta 50881 gtgcgtttcc tgaccgcgtg catttgtctt gtcggtcagc catccgcgct tgtcatagcg 50941 gtaggtcgtt ccttctccgg tagcattgcg ttcagctaaa agcaaaccac tggcatcgta 51001 ggagagggtg gtggcattgc cattggcatc cgtatagctc gttagacggc cttctccgtc 51061 gtattgctgc ttgtagacgg ctgcttcatt ttccaatacc tctgtcagac gtgcggctgc 51121 atcataggag aacttggttt tctgtccagc cgcattcgtt gtggcaataa cttgatggag 51181 cttgttaaat tggtattggg ttgatcgtcc gagtccgtct atatgagcaa gaatgtttcc 51241 tgcgccatca taggtgagcc cgctcacctt ctgtccggtt gcatcataga cggctagtaa 51301 acgtcccgcc gcatcgtatt catagcgctg ggtattcccc aaaggatcgg tgacagacgt 51361 cactctgccc atggcatcgc gttcgagact ggtcttcgcc ccggttgggt ctacgacacc 51421 aacgatctgc cattccttgt catactcata acgagttgtt tcaccatatg cattcgttat 51481 ggattctact ttttctgtaa tcgtgtaccc gatcttcgtc gatgctccgc tagccgtagt 51541 ctcctctact cgacaatcct gtgtatcgta ggtgaaggaa tgcatccttc cgagaggatc 51601 tatgacacct acaagattat cgttggcatc gaatacctga cgcagcgaac ccccaaaagc 51661 atctgtaaag gttgtcatcc tgcctgtagg gtcgaagcca acacggaaga tacgcccttc 51721 tgggtcttga gcggaaacaa gcattccctg tccatcgtaa tgataagtgg tttttgctcc 51781 tgtaaaatca atataagtgc ttctttgccc gtgctcgtta tacccgatgg aagagatgca 51841 gccgtctggt cgtgtaatgc tgaccagccg ctcgtgttca tcataggcgt aagtcgtgac 51901 tccgccttcc gcgtcttctt cagctgtcag taggtcattt tcgttgtacg tatacgtcgt 51961 tgtattgcca agaggatctg tctcttttac cagattcccg cgatggtcgt acgtataagt 52021 ggttgtctca cccgctccgt ttgtttcaga agtcgtttgg ccccactcat tgtaggagta 52081 tttggtgacc gttccatcct tctcagtctt ctccagcaac tggccattgt cgtcatggat 52141 catgatctcg acatgcccat tgccgtctgt aaaggtcgtg accatcatgc cagggcggct 52201 ctcggtatcg tagtgaatat aaccagggat gcctgccgcg tctgtctggc agatgatgcg 52261 cccttcttcg tcaaacgtat tcgtgtagac gatgacgcca tctgatgcca gagattccag 52321 ttggtcattt cctgtataag acaggtcagt gacaacacca ttcggattgg tatagcgaat 52381 catcctgcgg tcggcatcat acgaaaagcg aagggaacga gtcccatcag acaatgccga 52441 aaccaagcca tccaccccat actccagtga aaacgctcga cgactccgct cttctgtcaa 52501 gcgattcagc ctgccatgct ggtcatagct gaagagcagc gacattccgg cagccaccgt 52561 atggcgaagt gcttgtccat ttctggcaaa atcgtacgtc tctctcgttt ccttgaccca 52621 cagcgtatag ccgtcttgtc tttctcgcag ttcgtcaaaa aagacgtccg catcactgga 52681 ccggtataag ccgtcctgaa cgcgagtaaa ggtattggcg cggccagtat tccaccacac 52741 tgtaatttct tcgcgtgtct catccaggaa ttccaggcgc atttcataat tgtgtgtcca 52801 tgctttgccc agtgctccct cttgcaaaag cagggagttg taatgcagtt caaacgtcca 52861 cgtctcggcg ccatacagct tgagggcagg atgaacgata aactgcgctc cggtgccgcc 52921 atggatcggg tctttgatgc agcttttcgg ttttactttt ttgacgttca tctttcttac 52981 cttgcctggt ttcttgtgct tccctttgat tcttttccga gcccaggcca ttcccgttac 53041 ggtcgagaag acaccgtccg tcgcataatc taatgcctca gatccggctt ccttgaacac 53101 ttctttcaca acaggcttct gcatgaactt gccgaccatg ctcttcttca gcttctgcac 53161 agcggcaagc ttgtccatac tctcctgaat gttccgcgca gcagtaacga ccttgccttt 53221 cactgcgctt gctgcattgg ccgtcgcctt gacagctttc gatacaccca gtgctttgtc 53281 cgctgccttg accgctttcg ttgccttgga cattgctttg gttgccttca ctgctttcgt 53341 cgtcagcttt gccgcagtca ctgccgtacc cgcacctgga atcgcggctg caagggacat 53401 agcggcacca gcataatcgc cacgtgcgac agatatcccc gcattgacga cgtctgccac 53461 ttccccgatg acagggatca tccctacgat atcgagtcca agctgtaagc tatcgaggaa 53521 gccccatcca gacttctctt cttcctgctc ctcctcaacg acttcttcct cttcttcctc 53581 ctgcggcaaa tcctccacaa ccacaggcgc cttcgtcagc ccgaccatct caatctttgg 53641 cgcttgaaga tcgacttccc cgtccaaaat catgctgctg gtgctgcaca tgaggtagat 53701 cgcttccttg gccttgatct cgaccttcgt atctgacgta atttccatat ccttttccga 53761 ggaaaatacg atcggatgca tactgtgaat ctcgatgccg tcctcttcgt gcagcttgat 53821 aaaaatattg ccttcttcgc tctcttttgc cgtaagaacg agctccttgc cgcccatcat 53881 cagctctttg ccaaagttgg ttccccagta cttgatgccg ggattgcccg ttttcgccgt 53941 gctgcctccc ccttttcgca cggagctgac tgccatggct ccttcttcat ctggcgtaga 54001 gaagtagagc ttcacggagt cgcccatttg cggcatgcag tgaaagccgc tgttgccctc 54061 tgccgagtag accgtggcat aagggaacca gctcgcctct gccttgggct gcttcggatc 54121 gatgtcgagg tggattttga cggtatcctt ttggatgtcg atgatcttgc cttccagggc 54181 agcgccgcat atgtcgtcgt tgcggatagg gttttgacga atgcctgctt cgggcatgag 54241 ctgataggtg tgaatcagca gggcatggtc gatcctcgtt gttgacccgg cgacgaccag 54301 ctctttgcct tggtagttca cacggtctcc gagctggagg acctgtccgc tttctacttc 54361 ataggtgaga aaatcgtttt ccgacatacc tgccgcgtag ccgttttctg tcgtttccat 54421 atagggagaa agccttttgc tgatggtgta gctagcgtct gtcaattggg cagtgcgtcc 54481 ctcgggcaag ccgaaccaaa acttgggcgt atctgccact gcctcagcga cgagaatgga 54541 accaaagcgg gaggctagtc gctttaaaaa ctgccaatct gtttcctgat actgaatggc 54601 aatggtcccg agcggcgctc cgttcgaagc atggtccaaa taatccgagc cgggatagtc 54661 cttcgtgatt tcatccagca gactggcata cgtcatttgt ttatgctgaa aagagcgcat 54721 cttgcgctgt ccgtccattc gctgcgtgtg cgagaccgct tccagctcca aatgatacac 54781 gccgtgaaca aaattcacac tgacggaatc cacgagtcct ttgaacagtg tcttcgtaag 54841 cgaaccgttt tccactaaat tcagcgcgac tgtatcctca ctcgtcgcca tctcgatgta 54901 acggtcgctt ttctcctccg ggatgattcc ggtgacgaac aatctggcgt gctcattgac 54961 tttcttcacg attctgacat cctgcaggct ttggatttca aagggtgaga ccaactgaat 55021 attctcgtat ccagccagct tctctgtcgt attcatacaa tccccctcac gattgctcct 55081 gtccgtcgtc ttcgatgcga atgcagcctc catagatgca catgttcgtg ctggtgttta 55141 acagggcggg atgattttcc acgagtacat ctgccttgcc atcgatccag ggcatggtga 55201 ccacaggaac gcatggcatc ggcttgagca cgccgttgtt ggcagcagta gcagctgcga 55261 cggttggatt tttctcgcat ttacatttgc caaacggcat gatatttact tgcggcacat 55321 agtcattcac gttcatctgt gcctggttgc gaatgtacac accatgacta aacggcgttt 55381 tcagcttgtt cttctggctc ccgtagtcgc acgtgagaat tgctcctgcc acaacgtagc 55441 ttttcttcgg agcggacgaa ggcactacat cgacatcttc aaccatgggc atgactcatt 55501 ctcctccctg cttgctctgc ttttttcaag cggataccga aaaagtccct gcgcagcaaa 55561 gcctctgcca gccgcaaatc gatgatgata tacggttcac gaatgccttc aatttgaaaa 55621 atcgtacggc gcccaatctt ttctggatcg agaaccagcc ttttgagtga gccgtcccgg 55681 tgaaattcac tttgctcgga caagcagttc acacgcggca ggatcatcag ccagtacaag 55741 tcctgcttga tcctttccat gtccaccagt acgacagatt tgacgaacag cttcggtgcg 55801 aacttgtgga tgattgtctt taagcggttg gaataaagcg ggatgggtct gtcgagaaaa 55861 tccaggtagt cgttctcttt cttttgcttg atgtcgaact ggatgacggc ctcgtccagc 55921 cttcctgata atgcgggggg tgagcaatcg ctcatttgat tttgaacatg taaaaaaggc 55981 tgattccatc attgttgaaa gatggaatca gcctttgaaa gttaactaat catggtgttt 56041 cttatttgta aattgattgt attgtacatt catgtttttt ggggattaca cgggtttaca 56101 cttaattcac gacgaacctc tatcctaaat tacttacatc gcaacatcct ggtatcctac 56161 tctggctact tcttcattta ttagtagtaa acctaaccca ttttcttcgt cccatgtgca 56221 gtcgaaagtt aaaccgatgt atctgccttc caaacctttc gcaaagggaa tagatattcc 56281 tactaaactt atataatcaa gtagctgctc ggctgtttca attaaagggt aattctcgtt 56341 aagtcctgca tcataattct gctcgtaata atctagaatt ggttgtaaaa tactttgttg 56401 aagttgctcc caactttgaa tcaatgagtg atacgctgca tattgttttt cggaaaattt 56461 accatcttgt tcaccactta tcattaatgc aatctcaact tcttctccac aaaattcaat 56521 agtagtatcc ttaaaccatg cataattgta ttcgagttcg ccaaaaactg catcatttat 56581 tgtcatttta aaatctcctt tttaaatttc gttttattta tttcttttta tttacgaatc 56641 ctcaaggtac agacgactta ttggcaaatc ccccggctta aacgctgcta cgtttatcta 56701 cccaatccac caaaggtgtc gattagaact gtttatcttt tgtgaaagga caaaattgac 56761 atgaacaaaa aagcttactc ctcctcgtat ggcaagttgg aatacgcctt tcaaagttta 56821 taaacgtgtt tttcatgttt tttagtgttt ggtttgtcgg ttttgtacga tcttgttgtt 56881 aggcttgtaa gccatttata ctcaaaattt ttgacagact gggagaccca agccttctaa 56941 gttgagccat taaagagatt tactttttat ctcttcaaac cattcatcag caaagtcatc 57001 agccgttttt atatcatcat ttgtgtgcac taaatcatac ttgtattcag cttgaaactt 57061 gccactcgta gcatcatata ttaatttcat ctcagttggc atgtcttttt caaattcttt 57121 gcacaattct tcgatttttt ctatattatc attgataata tttaatacca taaactgtct 57181 ttctgtagaa acatcataac tttcgtcccc atcctccaat acatcattca acttatgaca 57241 ctctacatat ttattattaa ttaaataaaa gaaactactc gatatcatat cttcttcaca 57301 tgaagcataa acatatactt tattggccct atctcccaca tattccatac atatagatat 57361 catatctgct tgcaattcac taaacctttc ttcaaatcct ttcataacta cattcctctc 57421 cttttaaaaa tttttaaatt ttgcactagc tgctttacca tcaatagtgt agttaacaat 57481 aaatttgtcc ggacgcatat tattaccaga gtaaactatt tcaacatcaa ctgttacttt 57541 tttgggaggt tcttctttca aagccgcagc ccatttattt tcgattttct tatatttctt 57601 ctgattaacc tctgataatt gtgaaaccaa attgtcaatt ttaggtgagc ctccaaatct 57661 atcacctgcc aaatgtccta catttttacc cggtgtattt ttgctgtgtg acaatctttc 57721 tgttctcttt gttaattgta aattatccat ttcaaactta ccaatcctac ctaggctatc 57781 tgtttcataa aaataatcct attctccagt tttataccta atattaggct tcaatttatt 57841 ttttcgtcca tttgtaaact gttccccttc gcctactaat ggttttggtt taacttcact 57901 tacatccgca tcacttttac ccgtcccctc agtatccctc tgctcttgtt ctcttctctc 57961 tcccgttctt ccttcccatc cctaggacga tgatgccctc catcccatac aaaacaggct 58021 cattcctctc atcgttcgag ttggaataag cctttgaaag tttatcaagt gtttgtcaaa 58081 ttgtttggtt tgctggttat attgtattct ccctgctgtc agaatatttt tctgtatttt 58141 atgtagtagc tatatgtctc ggttaaataa tgggtttatt cggcattagg tagcccgtat 58201 acccaagcat tcaaatcgca acatcctgat accctacttc aatcacctct tcattcaaca 58261 aacggagtcc caggccattt tcctgatccc atgtacaatt aaaaagtatt ccaatatctc 58321 ggccttctct aatatctcca tatggaacaa caattccatc caaagtaatc atctcaagaa 58381 gttggtcggt tgtttcaact aagggataat tctcattaaa tgcaatatca taaccgagtt 58441 catgtcgctt ttgttggtaa tagtctaaaa ttggttgtaa gaagctttgt tgcaattgct 58501 cccaatcttg cattaaagat tgatatgccg tatattgttc ttcatcaaac tcgccatctt 58561 cttcaccatc aatcatcaat gcaatctcag tttcttttcc caaaaaatga atatgggtat 58621 ccttagacca actatattta tactcaagtt caccaaaaat cggatcgttt tttgtcattt 58681 tattatctcc tatttttgtt tattggcaaa tcctccaggt tcaaatgccc ctgcattaat 58741 ctcccccaca ccaccaagat gcccaaatgt actgtttata tttgttggta caagttgcat 58801 tgttttgacg tcatttagtt catgccatgt taatttgttt ttttctcgat aaacctttac 58861 atctttagca ctaattctac cagactccat cccgaattga cgtgctaatt caggagaatt 58921 atttagttgt tcggctaatt tttggtctga ttgaataaaa ttttctcgtc tagctttccc 58981 tccataagtc ccctttccac cgagcatata ctcaatttct acttgtgctt ttgccactgg 59041 tgaaaaatcg ggaacagcat ttttatattg tataccatca ataccggctt catctaatat 59101 tcttttcaat tgagggtctg gcggcggctt aagagtacat agagattcac cccttgttcc 59161 ttcaaaacca acttttagat aatcaggtga aggtgtttga ttatatctag cttcatatga 59221 actggcaaat ttagtttgct tgaaggcagg tggaatatta gtaccattac ccatcccctc 59281 agtctctggt ggtttctcac cctcaggcgg cttcaccggc ggcttttgat tcggcttctg 59341 tccattcggt cccccatatg tttcgcgcca cttcagttgg ttctccgtag gggcaagctc 59401 taccacatct tttttattcg agaattttat tggaaaccct tccgccgatt gtaactgagg 59461 gcctaaacta tccgctaaat tctgcaagcc ttcttgcata tcatcgcgca gcttcctagc 59521 cttttgcttg agctgttctt tcatctgtgt tgccttgttg atgactgcat cttttgcggc 59581 catgacgcta gcgtacaact gctccttgat tcgctggacg gcttgcacca catccatctc 59641 atctagtgtt ttgcgggctg ccgtccagac cttcccgacg gtgctttcga cggtatttgc 59701 taccgtcttc actacatccg ccgctgagtc tgctacctcg agcactttct gtcccgcttt 59761 cgttcccttt agtgctttat gcgcctttgc tcccagcttg gctcccgttg ccgcccagcc 59821 tgcaaaaggg atacacgccg ccagagatag cgctgctcct gcatagtctc ctcgtgcgag 59881 cgagattccc gcattcgcca ggtcagctac ttctcccaga cccggaatga gtcccacaac 59941 atccagcgct aactgtacac catccagaaa tccaccccag ccagactctt cctcttcctg 60001 ttgctcctct tcctcttctt cttcctcctg cggcaaatcc tccacaacca caggagcctt 60061 cgtcagcccg accatctcaa tctttggtgc ttgaagatcg acttccccgt ccaaaatcat 60121 gctgctggtg ctgcacatga ggtagatcgc ttccttggcc ttgatctcaa ctttcgtgtc 60181 tgacgtaatc tccatatcct tttccgaagt aaaaacaatg ggatgcatac tatgaatctc 60241 gatgccgtcc tcttcatgca gcttgataaa aatattgcct tccttgctct ccttggcagt 60301 aagaacgagt tccttgccgc ccatcatcag ctctttgcca aagttggttc cccagtactt 60361 gatgccggga ttgcctgtct tcggggtgct gcctcctcct ttgcgcacgg agctgaccgc 60421 catggcgcct tcttcgtctg gcgtggagaa gtacagcttc acggagtcgc ccatttgcgg 60481 catgcagtga aagccgctgt tgccctctgc cga //