LOCUS       NZ_CP017172            21386 bp    DNA     circular CON 06-MAR-2024
DEFINITION  Myxococcus xanthus strain KF4.3.9c1 chromosome, complete genome.
ACCESSION   NZ_CP017172
VERSION     NZ_CP017172.1
KEYWORDS    RefSeq.
SOURCE      Myxococcus xanthus
  ORGANISM  Myxococcus xanthus
            Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
            Myxococcaceae; Myxococcus.
REFERENCE   1  (bases 1 to 9429999)
  AUTHORS   Wielgoss,S., Wolfensberger,R., Sun,L., Fiegna,F. and Velicer,G.J.
  TITLE     Social genes are selection hotspots in kin groups of a soil microbe
  JOURNAL   Science 363 (6433), 1342-1345 (2019)
   PUBMED   30898932
REFERENCE   2  (bases 1 to 9429999)
  AUTHORS   Wielgoss,S. and Velicer,G.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-SEP-2016) Institute of Integrative Biology, ETH
            Zurich, Universitaetstrasse 16, Zurich 8092, Switzerland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Genome Coverage                   :: 25x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/06/2024 02:13:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,783
            CDSs (total)                      :: 7,699
            Genes (coding)                    :: 7,611
            CDSs (with protein)               :: 7,611
            Genes (RNA)                       :: 84
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 88
            CDSs (without protein)            :: 88
            Pseudo Genes (ambiguous residues) :: 0 of 88
            Pseudo Genes (frameshifted)       :: 29 of 88
            Pseudo Genes (incomplete)         :: 73 of 88
            Pseudo Genes (internal stop)      :: 6 of 88
            Pseudo Genes (multiple problems)  :: 19 of 88
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:23:50
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7777085
            Orig. end                         :: 7798471
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP017172.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source strain/DNA available from Prof. Gregory Velicer, IBZ, ETH
            Zurich, Universitaetstrasse 16, 8092 Zurich, Switzerland.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21386
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21386
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21386
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11386](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11386
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(285..419)
                     /locus_tag="BHS07_RS40785"
     CDS             complement(285..419)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BHS07_RS40785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_257792419.1"
                     /transl_table=11
                     /translation="MTERRRLRDRCQAVLITPRGRHQQQIAKDLGPDAAQYLWPLTAG"
     gene            595..1341
                     /locus_tag="BHS07_RS32075"
                     /old_locus_tag="BHS07_31295"
     CDS             595..1341
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011556105.1"
                     /locus_tag="BHS07_RS32075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31295"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_237077620.1"
                     /transl_table=11
                     /translation="MMGATRESNPLYAKVELTLASEIAAGVLPPRSQLPTEDRLIERFG
                     VSRTTVRKAIENLVARGLVEIRRGIGTFVAQPKIIQELTELTGFVEDMQALGRTPTARL
                     LDSQLVPADADVARQLVVSPGSLVMRIQRVRLADGMAMSFDETYLPREIGEKIVTHDLE
                     TEPIFALLEERYHLPLIEAEYRLEAITATPTVAQALAVEPGNPVFLIERTSYSEGSRPI
                     DYERLHYRGDLIRFITRLSRRPRARS"
     gene            1357..2223
                     /locus_tag="BHS07_RS32080"
                     /old_locus_tag="BHS07_31300"
     CDS             1357..2223
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011556106.1"
                     /locus_tag="BHS07_RS32080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31300"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_140795105.1"
                     /transl_table=11
                     /translation="MNPTMVFWLFAAAFGASALGGVLGMASGIFIVPILTLFFNIDIHV
                     AIGASIISVIACSCGSAAPLLKRRLTNIRLAIVLETATTLGALTGVFLIGIVSNSFLYG
                     LFAFILTLSAKQMLARRREVEVADTSGPNVKSLATVLRLHSSFPDHASGRDVPYQVGHV
                     PISLALMYGAGVISALLGIGSGVLKIPAMDTALRLPIKVSSATSNFMIGVTAAASAGAY
                     FVRGDIDIGIAGPVALGSVVGALVGARLLMRLPAEKIRISFVVILTLLAVQMLLSALGV
                     QFLGGSA"
     gene            2220..2537
                     /locus_tag="BHS07_RS32085"
                     /old_locus_tag="BHS07_31305"
     CDS             2220..2537
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011556107.1"
                     /locus_tag="BHS07_RS32085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31305"
                     /product="DUF1634 domain-containing protein"
                     /protein_id="WP_140795106.1"
                     /transl_table=11
                     /translation="MKPTTNRLGRCEQSIAGLLWNGTWLASALVTAGIALGATHDVWSF
                     LAPSLSGYDVMKTGVALFIILPIARVALMLVMSLRERDYIYTAISVFVLAVIAAGVMVE
                     L"
     gene            3088..4095
                     /locus_tag="BHS07_RS32090"
                     /old_locus_tag="BHS07_31310"
     CDS             3088..4095
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011551807.1"
                     /locus_tag="BHS07_RS32090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31310"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_140877177.1"
                     /transl_table=11
                     /translation="MQNKTWTDAALLEHLQKAVYLELWTIPLYLTAAYSLQVPGTNAQL
                     PPQQVTVRGKKNPNRSREQLAFNNIYSVVVQEMLHLELASNLFNALFAPKGYSPKFTGE
                     WAPRYDRFPSWIAVNKPVKLGPVDPEQMSLLAAIETPEPKSDGVQNGPQDAYDSIGQFY
                     KAIEQGINQRWNELYQPDADHRQKSEFANPQYKSDDYTRFSSTIGGDSRTALKQANEVL
                     QAIVGQGEGNLGPVIDSELRPEDANDLEDQFSHFARFRMVQAMLKFGGPLKTYPTTESS
                     GLAAAQQQLTTGFTSLLTALEKGYAGDDELDLGSMWALPKQIVSVWSAGGVPQF"
     gene            4316..5707
                     /locus_tag="BHS07_RS32095"
                     /old_locus_tag="BHS07_31315"
     CDS             4316..5707
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002616357.1"
                     /locus_tag="BHS07_RS32095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31315"
                     /product="hypothetical protein"
                     /protein_id="WP_335928986.1"
                     /transl_table=11
                     /translation="MSLAHVASTAYSSGPLLLMPPVRQPLLWLNCVALALAIAGCGSTN
                     PPDKPTDYVHPLAEGSPICGRADFDEMFPYSIRSKTLPVIVHYYREVERETAQQVLTYV
                     EKGWDYHVKRLGMRPAITDQGECGPDEAFDVFVWKGHRSCLVNVLSGDPSTPWDDRRGF
                     MVVDPWGPYGGPELEETVVHEMAHASQAADDWYESPITFEMSAVFTDQVYANRYIKTYF
                     DDFQAHPDWALDRDDKYETWYMYGASLYLLYLKDRFFDGDPGFLSRMWLASRNPPGAEN
                     DPTLNEPDFADALDAMLADKGFSYVETVPEFSRWRWYTGDHVDDRHFHHFQGGLDNLKA
                     AKLALAADQEASPGTLRVTEDAPMMLGTSYLSLRTGASTPNALYVSLEAPADARRRFVV
                     QAVPGLTPDSDGETLDLSSGPKPLHFTADSTRTLIVTVLPTGPYDPDLRDEDRYPFSIV
                     LSTHP"
     gene            5744..7060
                     /locus_tag="BHS07_RS32100"
                     /old_locus_tag="BHS07_31320"
     CDS             5744..7060
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018561.4"
                     /locus_tag="BHS07_RS32100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31320"
                     /product="DUF1214 domain-containing protein"
                     /protein_id="WP_140877179.1"
                     /transl_table=11
                     /translation="MTPLPPDEAQKIAYHAFMYGYPLVENYSILWQSTLAIQQQFNTFY
                     GKARLTTPNDTTVITPNNDTAYSQGWLDLGAEPIVLQVPAVPQNPPRYYSFTIIDACTN
                     NVGFVGSLTTGTAAGNYVLAPPGMVPGSVPNATVIPVPSRYIFLLGRTQLLGTNDIPAT
                     QALMDQYTLVPLSQFLGQPAPAPAPATPFLPIAPSFITTLAFFQYLNLALTFQTPPAGD
                     APLLESFAQIGVGPGLPFNPSTLDPKLAGALQRGILEASNAIKEMTHHGIVKNGWNLPE
                     VNRPYFGTKWWTDYRFRSRTAQAGIYPVSPSEAIYYRAYQDESSKPLAGTNQYTVTFPA
                     GQLPPAASFWSLTMYGENQLLVPNSINRYSLGTQSNLSIAADGSVTIYIQANAPSAAEM
                     PNWLPSPASGSFYIVLRIYGPENTSYIAPGLVQVGSSGS"
     misc_feature    complement(5789..5800)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            <7311..7961
                     /locus_tag="BHS07_RS32105"
                     /old_locus_tag="BHS07_31325"
                     /pseudo=""
     CDS             <7311..7961
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011985390.1"
                     /locus_tag="BHS07_RS32105"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="BHS07_31325"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="QNVSALVAFGEGKDGHRHLLAIILGSQSVDSWLELLRQPLERDLR
                     GVRLVIADGHAGLASAVWQQLPEAQLQRCTVHSTRNVFAKAPWRLRGRLGKDTTDVVEA
                     PSPLGRQEAPGGAPGRPGATGPRGHGVSREGFAAATRSFSFPWAHWKRLRSTKGLDLLL
                     GKVERRIRAAGAVLDRVSALRLVTSVARQVTRVWDDRRYHDRPLLRSNTDTHS"
     gene            8341..9207
                     /locus_tag="BHS07_RS32110"
                     /old_locus_tag="BHS07_31330"
     CDS             8341..9207
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BHS07_RS32110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BHS07_31330"
                     /product="hypothetical protein"
                     /protein_id="WP_140799864.1"
                     /transl_table=11
                     /translation="MSLDQFLAAPIEQVRRIAPATLIWVVEGTRRSAALAGIDVSSEDY
                     AHWSISQMKACVELFFHHGVRHVITPLLTPSQFAEVTPHYRERLFDWVALFVKEFSLLT
                     TSQHQDWRLRLLGAESLPDELRPLSEKVAAATPRGKHTLWCSVVAQSGAPWNELLQAVI
                     RTGARTREDAIRALYGEDIPLAQLMIAFGKPMVSPEQVPPLLQGPMDCYFTQRPGYRLT
                     ERELRTVLYDHAYLRRTWRADKTGRAEEAISHRRAWEEGPMVGLGIRLGPFWYPAPMTV
                     PPLEDTH"
     misc_feature    complement(9439..9453)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.21"
                     /tool="antismash"
     gene            9530..>9700
                     /locus_tag="BHS07_RS40435"
                     /pseudo=""
     CDS             9530..>9700
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013003.4"
                     /locus_tag="BHS07_RS40435"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="pentapeptide repeat-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWNQWRKDNPDIRPDLTGVRFDGFDLSRFDFSGADFSRASLLDTN
                     LRDARLTGADLT"
     gene            10001..11386
                     /locus_tag="BHS07_RS32115"
                     /old_locus_tag="BHS07_31335"
     CDS             10001..11386
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="BHS07_RS32115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31335"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_237081975.1"
                     /sec_met_domain="T2TS (E-value: 7.5e-34, bitscore: 115.9,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPELRPHLRATRRWVQAAPVQKHHEVPRLIESWLQGWVGSTAPTA
                     TLDVSHPLFSEPVFCDRRNFFLALALAVGAPVRGGPSREELQAQLLERLRARQTVRLKR
                     WSGAELAALFLLLADEAPSADTVEALKALREAQSTSGSFGEQMGATLVALAALRRWDPT
                     SEAFARALDFLLHERTTAGVWCFSPAEVWDTALLCRALEGCEDLEPAMFERAWSFLLRS
                     QNEDGGWSYREGVESDTDTTSMAMLALPRTDAGTSASGLGRAYLERMQTPAGLWLTWQS
                     RDDPPAEDVVAHAIMALRKWGTVPAFWAPAGEWLALRARQEGGCRAHWYNIDSYASHEV
                     GLALGPSHDSTRHLARELVERQNPDGGWPPTQGAASSAAATGMALALLTFYLPNEHLCV
                     TRAIHYLAELQEPGGSWPGPLQMYGPRPFAIDYPMQIHALSVHGLAAVARASRTPPRPL
                     TEL"
     misc_feature    11159..11161
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(11474..11492)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.12"
                     /tool="antismash"
     misc_feature    complement(11623..11632)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     gene            11724..12509
                     /locus_tag="BHS07_RS32120"
     CDS             11724..12509
                     /GO_function="GO:0045152 - antisigma factor binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.4"
                     /locus_tag="BHS07_RS32120"
                     /note="This anti-anti-sigma factor, or anti-sigma factor
                     antagonist, belongs to a family that includes characterized
                     members SpoIIAA, RsbV, RsfA, and RsfB; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="anti-sigma factor antagonist"
                     /protein_id="WP_161607135.1"
                     /transl_table=11
                     /translation="MSLKLSGESRLTFINDVTAATRVFLREAGFPDATAEHVELAVAEA
                     VANAIQHGNQGVESRRVDVMLVSLADRVTVSVRDEGAGFDVAAIPDALAPAHRLKPSGR
                     GVLLMRALMDAVELSPHPEGGTVVRLSKQQPRSAHHTPGERTMSELNIRERQSGDVTLF
                     ELAGRITIGAGDTVLRETVRTAIQDGRKNLVLNLAEVTYLDSSGLGELVSSYTTTSREG
                     GRLKLLSPSRKVQDLLMITKLITVFDVYDTEQEAVNSFK"
     gene            complement(14550..16304)
                     /locus_tag="BHS07_RS32135"
                     /old_locus_tag="BHS07_31350"
     CDS             complement(14550..16304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002621103.1"
                     /locus_tag="BHS07_RS32135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31350"
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_140877185.1"
                     /transl_table=11
                     /translation="MSYLLSRWLAAPVAALRAGLVLGLAASTLAACRDNEPPSIPPVTR
                     NITLETVEDTPLNLRLPATGNEALTFTIVDAPDHGTLSDISASGSVTYTPGADYNGEDA
                     LIFRATNRQGQSAQGTVTITITPVNDTPTLSSLANQTIAEDSSTGDLAFTLGDVETTAD
                     GLTVTATSSNTALVPDAPTNLVFGGSSTSRTLKVVPVANASGTTTVTLSVSDGSATAST
                     TFTVDVTAVNDLPTISPVANQSITAGSSTGDLAFTVGDVETAADSLTVTATSSNTDLVP
                     NDPSHLILGGSGSSRILNVVPVASASGSTTITLSVSDGAATTSTTFTVDVTGLASLYWI
                     TTAGSLWRVDVNGTNAIELKTGISGAGFVATDPVTRTIFYTRDSAIVRAASDGANPVDV
                     VADGGYPSALAVDSTNRRLYWSDFNGERIMRAELDGSNPTQVVGGINSPSAIAFDIPND
                     KMYVITYNNTSLVRFNLDGTNLETLASGLGGLGVGLAVDPSGGKVYYSTRGNSIYVSDL
                     DGSNATTLVTNQTTVHGIAIDATAGRLYWVDWLGGVLRSANLADGSDIQDVNSGSSRNL
                     GLAWMPAP"
     gene            complement(17532..17762)
                     /locus_tag="BHS07_RS39350"
     CDS             complement(17532..17762)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BHS07_RS39350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_161607137.1"
                     /transl_table=11
                     /translation="MERLAGQSHHLEHDTLPEVVSQPDAAVGRGQRLSLSTANALLQKF
                     NSYSHVKSLQPFIDVAGYEKKLAELLNPFGE"
     gene            17982..18887
                     /locus_tag="BHS07_RS32150"
                     /old_locus_tag="BHS07_31355"
     CDS             17982..18887
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020477596.1"
                     /locus_tag="BHS07_RS32150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31355"
                     /product="hypothetical protein"
                     /protein_id="WP_140877191.1"
                     /transl_table=11
                     /translation="MTSSPPPGAVAFVDRWRELFDACDWSGLRAHEHPDFPEAGPPRQN
                     DSFIRGLGKSSFQVTSATLKPFVQPRWSIFRTQRLHPQPTYWCDLVLKNAKGHETEAFI
                     ALAPWEGTEGAFRASYYVEIPPKKKVAPLDLGKERQRVAKFLAKAVKDFARVQDARPLQ
                     RLELQYSTDNGTLNVSFDLDPAAEPGRGDAMTHFGFAELLVPRWADMKEHRPSLVGLDG
                     AKLAAREDGTWGTPEAHAQLEEHLGKMLVATLLEMRDSGQFEALRASATAELGVEEHEG
                     HFGWPDYEERRRENRIASSP"
     gene            complement(19463..20479)
                     /locus_tag="BHS07_RS32155"
                     /old_locus_tag="BHS07_31360"
     CDS             complement(19463..20479)
                     /NRPS_PKS="Domain: PKS_ER (25-211). E-value: 5.5e-12.
                     Score: 37.4. Matches aSDomain:
                     nrpspksdomains_BHS07_RS32155_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002633067.1"
                     /locus_tag="BHS07_RS32155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BHS07_31360"
                     /product="alcohol dehydrogenase"
                     /protein_id="WP_140795115.1"
                     /sec_met_domain="ADH_N (E-value: 3.8e-30, bitscore: 102.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.4e-20, bitscore:
                     69.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARKMKAVQVKQAKGPLEVVGRDVLEPGSGQVLIAVDACGVCHSD
                     AITKEGWMPVQYPRVPGHEVVGRIDNVGPGVTAWKAGQHVGVGWHGGHCGQCPACRVGD
                     FVTCDFQQICGISYDGGYAEYMLAPQEALARVPDGMKSEDAAPLLCAGVTTFNSLRNMG
                     AKPGSLVAVQGIGGLGHLAIQFARKLGYRTVAISRGADKRKLATELGAHEYIDTEKGEV
                     GKALQALGGARVIMMTASSNSLVADMIGGLGRDGVLLLLGAGAEPIPVTSQQLIMKRQR
                     VQGWPSGIPQDSQDTMDFSALTGVRSQNEVFPLERAGEAFERMMSNHARFRVVLKMR"
     misc_feature    complement(19700..19702)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        complement(19847..20404)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BHS07_RS32155_PKS_ER.1"
                     /evalue="5.50E-12"
                     /label="BHS07_RS32155_PKS_ER.1"
                     /locus_tag="BHS07_RS32155"
                     /protein_end="211"
                     /protein_start="25"
                     /score="37.4"
                     /tool="antismash"
                     /translation="EPGSGQVLIAVDACGVCHSDAITKEGWMPVQYPRVPGHEVVGRID
                     NVGPGVTAWKAGQHVGVGWHGGHCGQCPACRVGDFVTCDFQQICGISYDGGYAEYMLAP
                     QEALARVPDGMKSEDAAPLLCAGVTTFNSLRNMGAKPGSLVAVQGIGGLGHLAIQFARK
                     LGYRTVAISRGADKRKLATELGA"
     misc_feature    complement(20813..20822)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     misc_feature    complement(21122..21137)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.88"
                     /tool="antismash"
     misc_feature    21281..21295
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(21364..21381)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
ORIGIN
        1 tgacgtgtcc gtcgcgtccg ttgacacgtc agccacgtca attgacacac ctgaaatgcg
       61 ggcatggtgg cgttgattcg tgtgcctgtg cctacccaaa cttcaggcgc tgcgtcacgg
      121 gtgcgccgac gtcacattcg gtagggcgtc actgccgtga gcgaggcgcg cgaggcagta
      181 atcgttcgcc gtgtcccgtc tcttccccct ggtgcacagc cttggcttca tcgaaacccg
      241 aacggctccg cgcccttgcc ccttcctctg cgcgcaggcg taagtcaacc ggccgtaagc
      301 ggccagagat attgcgcggc gtccggcccc aggtccttgg caatctgctg ctgatgacgg
      361 cctcggggcg ttatcagcac cgcctggcac cggtcgcgca ggcgccgacg ctccgtcatg
      421 cggaagcacg ccctgagctc gcccctctgg tcctcgctca actccagcca acgcacgcag
      481 ggtaaatccg agaaggactc gccgagtcgt gaatcaggga gtgaccctgc acatcaggga
      541 ttcttctcgc ttgagaggga ccttgacatc acgacatcat gatgtcgtga tgtcatgatg
      601 ggtgccacgc gtgaatccaa cccgctttat gcgaaagtcg aattgacgct tgcttctgaa
      661 atcgcagctg gggtcctccc tcctcgcagc caacttccca cggaggaccg cttgattgag
      721 cggttcggcg ttagccgaac gacagtccga aaagcgatag agaacctcgt ggctcgtggc
      781 ttggtagaga tccggcgcgg catcggtacc ttcgtcgcgc agcccaagat catccaagaa
      841 ctgaccgagc tgactggctt cgtcgaggac atgcaggcac tcggccgcac cccgaccgct
      901 cggctcctgg atagtcagct cgtcccagcc gatgctgacg ttgcccggca actcgtcgtg
      961 tcgcccggca gcctcgtcat gcgtatccaa cgcgtgcggc tcgccgacgg catggccatg
     1021 tccttcgatg aaacctacct gccgcgcgag ataggggaga agatcgtcac ccacgatcta
     1081 gaaaccgagc caatattcgc actgctcgaa gaacgatacc acctgccact gattgaggcc
     1141 gaataccggc tagaagccat cacagccaca ccgaccgttg cgcaggccct cgccgtggag
     1201 cccggtaacc cggtcttcct gatcgagcgc acgtcatata gcgaagggtc tcgccccatc
     1261 gactacgaaa ggctccacta tcgcggcgac ctcatcaggt tcatcactcg cttgtcccgg
     1321 cgtccacgcg cgcggtcatg agccggagac acgtcaatga accccacgat ggtcttctgg
     1381 ctgttcgcgg ccgcctttgg cgcgagtgcc ctcggcggcg tgcttggcat ggccagcggc
     1441 atcttcatcg tgccaatcct cacgctgttc ttcaacatag acattcacgt agcgatcggc
     1501 gcgagcatca tctcggtgat tgcctgttcg tgcggcagcg ctgcgccgct cctgaagagg
     1561 cgcctgacca atatccggct tgcgatcgtc cttgagacag ccaccacact cggcgcgctg
     1621 acaggcgtgt tcctgatcgg catcgtctcg aattcgtttc tgtacggcct gtttgctttt
     1681 attttgacgc tatccgcaaa gcagatgcta gcgcggcggc gcgaagtgga agtggccgat
     1741 accagcgggc caaacgtgaa gagtctggcc acggtgctac gcctgcattc gagctttccc
     1801 gaccatgcat cgggccgcga cgtgccttat caggttggtc acgtgccgat cagcctggct
     1861 ctgatgtacg gggccggcgt gatctcggcg ctgctcggca tcggctccgg cgtgctcaag
     1921 atccctgcca tggataccgc cttgcggctg cccatcaagg tctcgtctgc cacatcgaac
     1981 ttcatgatcg gcgtgacggc cgcagcgagc gctggcgcct acttcgtgcg aggcgatatc
     2041 gacatcggca ttgcggggcc tgtcgcactt ggatcagtcg tcggggcgct cgtcggagcg
     2101 cgtttgctga tgaggctgcc cgctgagaaa attcgcatct ccttcgtggt gatcctcacc
     2161 ctgcttgcgg ttcaaatgct cctgagcgcc cttggtgttc agttcctcgg agggtcggca
     2221 tgaagcctac gaccaatcgc cttggtcggt gcgagcagag catcgccgga ctgctttgga
     2281 acggcacttg gcttgcgtca gcgctcgtta ccgccgggat agccttgggc gcgacacatg
     2341 acgtctggag ttttctcgcc cccagcctca gcggctacga cgtgatgaaa accggtgtgg
     2401 ccttgttcat cattttgccc atcgcgcgtg tggcgctgat gctggtcatg tccctgcgcg
     2461 agcgcgacta catctatacc gcgatttcgg tgttcgtcct ggctgtcatc gcggccgggg
     2521 tcatggtcga gctgtgagcc tgtgacatgc tcccgaaaac tggaccggat ttcgcgtggg
     2581 ccctccactg ggggaacgta cgggacgcaa gcaggtaaac ggaagagcag cgcatgtgga
     2641 tgctgtagaa ggtcgatgcc ggagccgagg cgaaggcggt ctgccggcgg catggggtga
     2701 ccgagcagag cttctacctg tgccgccccc aagacgggtt gctgcgtcat ggatgcttca
     2761 acgcgacact cggcagtgcg tcactgccgg tgagcgaggc gcgcacgaag gcgagggacg
     2821 aacacttccg cctggttgtg agcgcggcgg gcgagcacgg cttggccgcc cgcaggcttc
     2881 tcaccacgcc caacgcaaag ttggcggaca cgtcagcctc cgtcactgac gtgtcagtga
     2941 cacgggattc ccctggcacc cggagcctgg catcaccgca aggagttgaa atgactggag
     3001 ccgttcttcc gcaagccctg gcgcgaacat tgctcttgtc gccggcacat ccatccacgg
     3061 cgcctcgcat caacctcaga gttctccatg caaaacaaaa cctggaccga cgcggccctc
     3121 ctcgagcatc tccagaaagc cgtctacttg gagctgtgga ccatccccct ctatctgacg
     3181 gccgcctatt ccttgcaggt tcccggcacg aacgctcagc tcccacccca gcaggtgacc
     3241 gttcgcggaa agaagaaccc caatcgaagc cgggagcagc tcgccttcaa caacatctac
     3301 tcggtcgtcg tgcaggagat gctacacctc gagctggcca gcaacctctt caatgcgctg
     3361 ttcgccccca agggatactc gccgaagttc acgggcgaat gggcgccgcg gtacgacagg
     3421 ttcccgtcct ggatcgcggt caacaagccc gtgaagctcg ggccggtgga ccctgagcaa
     3481 atgtccctcc tggccgccat cgagaccccc gagcccaaga gcgatggcgt gcagaacggg
     3541 ccgcaagatg cctacgattc catcggtcag ttctacaagg ccatcgagca gggcatcaat
     3601 cagcgctgga acgaactcta ccagcccgac gcggaccacc ggcagaagag cgaattcgcc
     3661 aacccgcaat ataaaagcga cgactacacc aggttcagca gcaccatcgg cggtgacagc
     3721 cgcaccgcgc tgaaacaggc gaatgaggtg ctccaggcca tcgtcgggca gggcgagggc
     3781 aacctgggac ccgtcatcga ctcagagctc cgccccgagg atgccaacga cctagaggat
     3841 cagttcagcc atttcgcgcg attccggatg gtgcaggcaa tgctgaagtt cggcggcccg
     3901 ctgaagacct atcccaccac ggagagcagt gggctcgcgg ccgcgcagca gcagctcacc
     3961 accggattca cgagcctctt gaccgcgttg gagaagggct atgccgggga cgacgaactc
     4021 gacctcggta gcatgtgggc tcttcccaag caaatcgtgt ccgtgtggtc tgcgggcgga
     4081 gtgccgcagt tctaagagtc cctgacaaag tcagggctgg gcgggtcgtt ggaaagggcc
     4141 gtggcggagt cagcctgtcc acgcagttgg ggactcggcg cccgccaatg cctgaggagg
     4201 tgctcgcgct gggcgcgctg cccggactcc tcccgaacac ggccttgagt gcgaatcact
     4261 caaggtcgtc accgccgacg cctcatcaga tgcttcacct ctcaaggacc aggccatgtc
     4321 gctcgctcac gtcgcgtcca ccgcctactc atctggcccc ctcctcctga tgcctcctgt
     4381 tcgacagccc ctgctctggc tgaattgcgt cgcgctggcg ctcgccatcg ccggctgcgg
     4441 ctcaaccaac ccgcctgaca agccaacgga ctacgtccat ccgttggccg agggctcgcc
     4501 catctgcggg cgggcggact tcgacgagat gttcccctat tccatccgct cgaagacgct
     4561 gccagtcatt gtccactact acagggaggt ggagcgagag acggcacagc aggtcctaac
     4621 gtacgtcgag aagggctggg actaccatgt caagcgactc ggcatgcgtc ccgccatcac
     4681 ggatcagggc gagtgcggcc ctgatgaagc gttcgacgtc ttcgtgtgga agggccaccg
     4741 aagctgtctg gtcaacgtcc tctcgggtga cccctccacc ccatgggacg accggcgcgg
     4801 cttcatggtc gtcgacccgt ggggccccta cggcggcccg gagctcgaag agaccgtcgt
     4861 ccatgaaatg gcgcatgcct cgcaggccgc ggatgactgg tacgaatccc ccatcacctt
     4921 cgaaatgtcc gccgtgttca cggaccaggt gtatgcgaac cgctacatca agacctattt
     4981 cgatgacttc caggcccatc cggattgggc ccttgaccgc gatgacaagt atgagacctg
     5041 gtacatgtac ggggcctccc tgtacctgct ctacttgaag gaccgcttct tcgacggcga
     5101 ccccgggttc ttgtcgcgca tgtggctcgc gtcccgcaat ccaccagggg cagagaacga
     5161 tccaacgctc aacgagccag atttcgccga tgcgctcgac gcaatgcttg cggacaaggg
     5221 cttcagctat gtcgagaccg tccctgaatt ctcacgctgg cgctggtaca cgggagacca
     5281 cgtcgatgac cgccacttcc accacttcca ggggggcttg gacaacctga aggccgcgaa
     5341 gctcgcgctg gctgcggacc aggaggcatc ccctggcacc cttcgtgtca cggaggatgc
     5401 gccaatgatg ctgggcacca gctacttgtc gctgcggacc ggagccagca ctccgaacgc
     5461 cctctacgtg tctctggagg ccccagccga cgcacgccgt cgctttgtcg ttcaagcagt
     5521 gcctggattg acgcccgact ctgatggcga gacgctggac ctctcgtcgg gtccgaagcc
     5581 cctgcacttc actgcggact cgacgcggac gctcatcgtc accgtcctgc ccacgggccc
     5641 ctatgacccg gacctccgag acgaggaccg gtatccgttc tcgattgtcc tctcgactca
     5701 tccctaacag caccccaccc caccactgca agtccaagat accatgacac ctctgccccc
     5761 cgacgaagca cagaagatcg cgtaccacgc cttcatgtac ggttacccgc tggtcgagaa
     5821 ctactccatc ctgtggcaga gcactctcgc catccaacag caattcaata cattctacgg
     5881 caaggcgcgg ctcaccacgc ctaacgatac caccgtcatc actcccaaca acgacacggc
     5941 gtactcgcaa ggatggctcg acctgggcgc cgagccgatc gtcctgcaag tgccggcggt
     6001 gccccaaaat ccaccgcggt actatagttt cacgatcatc gatgcgtgca ccaacaacgt
     6061 tggcttcgtt ggctcgttga caaccggcac ggcggcgggc aactacgtgc ttgcgccccc
     6121 cggtatggtg ccaggcagcg tcccgaacgc gacggtgatc cctgtcccga gtcgctacat
     6181 cttcctgctc ggacgcaccc agctcctggg taccaacgac atcccggcga cccaggcgct
     6241 catggaccaa tacacgctgg tcccgctgtc ccagttcctc ggccagcccg cgcccgcgcc
     6301 cgcgcccgcg actcccttcc tgccgattgc cccctcgttc atcacgacgc tggcgttctt
     6361 ccagtacctc aacctggcgc tgaccttcca gaccccgccg gccggggatg cgccgctcct
     6421 cgagagcttc gcacagatcg gcgtggggcc cggcctgccc ttcaatccgt ccacactcga
     6481 tccgaaactg gccggtgcac tccagcgcgg aatcctcgag gccagcaatg ccatcaagga
     6541 aatgacccac catggcatcg tcaagaacgg ctggaacctc ccggaggtga accgtcccta
     6601 cttcggcacg aagtggtgga ccgactaccg cttccggtcg agaaccgcac aggcggggat
     6661 ctacccggtc tcgccctcgg aggcgatcta ctaccgcgcc taccaggacg agagctcgaa
     6721 gcccctcgcc ggcaccaacc agtacacggt gactttcccc gccggccagc ttccccctgc
     6781 tgcatccttc tggtcgttga ccatgtacgg ggagaatcaa ctcctggtcc ccaacagcat
     6841 taatcgttac tcgctcggga cccagtcgaa cctgagcatc gccgccgacg gctccgtgac
     6901 gatctacatc caggccaacg ccccatcggc cgctgagatg ccgaattggt tgccctcgcc
     6961 cgcgagtggc tcgttctaca tcgtgcttcg catctacggc ccggagaaca cttcctacat
     7021 cgcgccggga ctggtgcagg tcggcagttc cggttcgtga cggtcggcct cccgagcgcc
     7081 catcgagggc gctcgggctg gaccaccaag ggcatcgctt gcagtgagcc ctgcgctact
     7141 caagctccac cagttggcgc tccccgtccc ggaggacgcg caccggtcgc tgcatcccgg
     7201 cctggaagag cgacgcctcc atgggccgca cgaggcggtc cgcagtggcc tggaactcag
     7261 gaccctcgga ttggatagag cgtcacagcg agtgagagag gtgcgcagcg cagaacgtct
     7321 cggccctggt cgcctttggc gagggcaagg atgggcaccg acacctgctg gcaatcatat
     7381 tgggcagcca gtcggtggac tcgtggctgg agctgcttcg ccaaccgctt gagcgagact
     7441 tgaggggcgt gcgcctcgtc atcgccgacg ggcatgcggg cttggcttcc gcggtctggc
     7501 agcaactgcc cgaggcccag ctccagcgtt gcacggtgca ctctacccgg aacgtcttcg
     7561 ccaaggcgcc ctggaggctg cgtggccggc ttggcaagga caccacggac gtcgtcgaag
     7621 ccccctctcc cctgggacgc caggaagcac ctggaggcgc tccaggccgg cctggagcga
     7681 caggtccccg aggccatgga gtgtcacgcg aaggcttcgc cgcggccacc cgctccttct
     7741 ccttcccctg ggcccactgg aagcgcctgc gcagcaccaa gggccttgat ctcctcctcg
     7801 gaaaggtgga acgccgcatc cgcgctgccg gcgccgtcct ggaccgcgtg agtgcgctgc
     7861 gcctcgtcac ctccgtcgcc cgccaagtca cccgagtttg ggacgaccgc cgctaccacg
     7921 acaggcccct gctgaggtca aacacagaca cccattcatg ataccgccaa agagccttcc
     7981 tccccgcccc tcctgagcaa ttatacaaga ttcgggactt gaccctcgtg ggctgggccg
     8041 tgagggctcc cttttttgac tcccgcacga acgaggagtc gacaaagtca cgggaaaagc
     8101 ctacccctcg acccacatga caatggccat gcctcccccg tgcgcagcct ccgggagatg
     8161 atgcgggtag aaaaacctct ctcctggact caggacccgg cttgcgcccg gagccccttc
     8221 cgagataggc gctatcccta ctgccgcgcg ttcgacggtt ccgaacacat gaggtccgtt
     8281 gcactcgatt gaaggagccc gatgcctgac aagacacccg atatctcagc agcagaaccc
     8341 atgtccttgg accagtttct cgcggcgcca atcgagcaag tgcgtcggat agcgcccgcc
     8401 acgctcatct gggtagtgga aggcactcgc cgcagtgccg ccctggccgg catcgacgtg
     8461 agttccgagg actatgccca ctggtccatc tcccagatga aagcctgcgt ggagctgttc
     8521 ttccaccacg gggtgcgcca cgtcatcacc cccttgctca caccgagtca gttcgctgag
     8581 gtcaccccgc actaccgcga gcgcctgttc gactgggtgg cactgttcgt gaaagaattc
     8641 tcgctgctca ccacctccca gcaccaggac tggcgcctgc ggttgctggg cgccgagagt
     8701 ctgccggatg agctacggcc tctttccgag aaggtcgcgg cagccacccc tcggggcaag
     8761 cacacactgt ggtgctcggt ggtggcgcag tcgggggccc cctggaacga gttgctccag
     8821 gctgtgattc gcaccggagc ccgcacccgc gaggatgcca tccgtgcact ctacggcgag
     8881 gacatccctc tcgcccagtt gatgattgct tttggcaagc ccatggtgtc cccggagcag
     8941 gtccctcccc tgctgcaagg cccaatggac tgttacttca cccagcggcc cggctaccgg
     9001 cttaccgagc gggaactgcg cacggtgctc tacgaccatg cctacctgcg gcgcacctgg
     9061 cgcgccgaca agacggggcg ggcggaagag gccatcagcc accgccgcgc gtgggaggaa
     9121 ggacccatgg tggggctggg tatccgcctg ggcccattct ggtaccccgc ccccatgacg
     9181 gtccctcccc tggaggacac acattgaagt gacgtgctct tggactgcgc ccgctcattc
     9241 ccgcggtcca acacctcttg tcaccccacc cgtcgacaag gccggtggcc tcgtagaaag
     9301 acgacatgag ggaagttggg gcgacggccg gcgcacgccc catcaagtcg tacggacctc
     9361 gcttccaagg aagtgctggc gctcccaacg actccaactc gtggtgtgta ccgattgggt
     9421 atggccagtt tcatcagatg aacgcgatgt tcacttcgag gaagaaacgt ccatggcaga
     9481 ccgctctcac gttgagcaga ttggtgacgg gggccccacc gcccgcagca tgtggaacca
     9541 atggagaaag gacaacccag acataaggcc tgacctcacc ggagtcagat tcgacggatt
     9601 cgacctctcg cgattcgact tcagcggcgc tgatttcagc agagcctcgc tcctcgacac
     9661 caatctccgt gacgccagac tcaccggcgc cgacctcacc ggcgccgacc tcaccggcgc
     9721 cgacctcacc ggcgccgacc tcaccgacgt caccggaaac atcaaggctc aagggaagag
     9781 tgccgaggca cgaacaggcg cggtcctgcc agacggggcc cgtcacgcag aggagagccc
     9841 ctgtccgaag aatgaagacc ttcaacacca cgtgcggcgt gcgctgcgcc gcgcctgtgc
     9901 acatctggcc caagcccagt cagcggatgg tgcgtggcgg gtccccccct cgccaaggtt
     9961 ccttgagaat gccctggcgt gcttgatcgc ggatgcattc gtgcccgaat tgcgaccgca
    10021 cctgcgcgcg acacgtcgct gggtccaggc cgcaccggtc cagaaacacc acgaagtgcc
    10081 tcgtctgata gagagctggc tccaagggtg ggtgggcagc acggccccca cggccaccct
    10141 tgacgtgtcc catccgctct tctccgagcc ggtcttctgc gaccgccgga acttcttcct
    10201 cgcgctcgcg ctcgcggtgg gcgcacccgt gcgtggaggg ccgtctcgcg aggaactcca
    10261 ggcccagctg ctggagcggc tccgcgcccg tcagaccgtg cgactcaagc gttggtcagg
    10321 agcggagctg gccgcgctgt tcctcttgct ggctgatgaa gcgccgtcag cggacaccgt
    10381 agaggcgctg aaggcgctgc gcgaggccca atcgacctcg ggctccttcg gtgagcagat
    10441 gggggcaacc ctcgtggcgc tcgcggcgct gcgccggtgg gaccccacct cggaggcctt
    10501 cgcccgcgcg ctcgacttcc ttcttcacga gcgcacgaca gcgggggtgt ggtgcttcag
    10561 ccccgcggag gtatgggata cggctctgtt gtgccgagcg ctggaggggt gtgaagacct
    10621 ggagcccgcg atgttcgagc gtgcctggtc cttcctcctt cgctctcaga atgaggacgg
    10681 tggctggtcc taccgggaag gggtcgagtc ggataccgac accacctcga tggcgatgct
    10741 tgccctacct cgcacggacg ccgggacgtc cgcgtcgggc ctggggcgag cgtacctgga
    10801 gcggatgcag accccagcgg ggctgtggct gacgtggcag tcccgggacg acccacccgc
    10861 cgaggacgtg gtcgcacatg ccatcatggc gttgcgaaaa tggggcacgg tccctgcgtt
    10921 ctgggccccc gcaggggagt ggcttgcact gcgcgcgcgg caggaaggcg gctgtcgtgc
    10981 gcactggtac aacatcgact cttatgcctc tcacgaggtg gggctggcgc ttggcccctc
    11041 ccatgactcg acacggcatc ttgcacggga gctcgttgag cggcagaacc cggatggggg
    11101 ttggcctccc acccaagggg cggcgagttc ggcagctgcc acgggtatgg cgctagcgtt
    11161 actgaccttc tacctgccca atgagcacct gtgcgtgact cgcgccatcc actacctggc
    11221 agaactccaa gagccggggg gctcttggcc tgggccgctg cagatgtacg gtccaaggcc
    11281 cttcgctatt gactacccca tgcagatcca cgccctctcc gttcatggac tggccgctgt
    11341 ggcaagggcc tcccgtactc cgccgcggcc cctcacggaa ctctgagctt gcccgacgga
    11401 agcgggtgaa ggtcacagcg cctccggcag tcgtgggccg ggccctgcgc gccaccaact
    11461 tcggagtgca atgaaggctg agcctaccca aaccccggtc gctgcatcat cggagcaaca
    11521 agaccacctt ggacagtgcg tcgaggcgag tgcggcgctg cttcccgtcc atccttcttc
    11581 ctggggcgaa aggtcataac ccccagtcag tttcccaata tctaaaaaac caacatactt
    11641 gcaaaagcag attttcgagt ttactccata taaagcgatg gcttggcttt cttgaggccg
    11701 cgcgtccacg gccctggatg cccatgtccc tgaagctgtc tggcgaaagc cgcctcacct
    11761 tcatcaatga cgtcaccgcg gccacgcgag tcttcttgag ggaagcagga ttcccggacg
    11821 cgaccgccga gcacgtggag ttggccgtgg cggaggccgt ggccaatgcc atccaacacg
    11881 ggaaccaagg cgtcgagagc cgacgcgtgg acgtgatgct cgtctcgctg gcggaccggg
    11941 tgacagtctc cgtccgagac gaaggagccg gcttcgacgt cgccgcgatt ccagacgcgc
    12001 tcgcgccagc ccaccgcctc aaaccctcgg gccggggcgt gctgctcatg cgcgcactca
    12061 tggatgcggt cgagctctcg ccccatcccg agggaggcac cgtcgttcgc ctgtcgaagc
    12121 agcagccccg cagtgcccac cacaccccag gagaaagaac catgtctgag ttgaacatca
    12181 gggagcggca gtccggcgac gtgaccctct tcgaactcgc cgggaggatc accatcggag
    12241 ccggagacac cgtcctgcgc gagaccgttc gcaccgcgat acaagacggc aggaagaacc
    12301 tggtgctcaa cctcgccgag gtgacctatc tggacagctc tggactgggt gagttggtca
    12361 gctcctatac gaccacgagc cgtgagggcg gcaggctcaa gctgctgagc ccctctcgga
    12421 aggtccagga tctactaatg atcaccaagc tcatcaccgt ctttgatgtc tacgacaccg
    12481 agcaggaggc ggtgaacagc ttcaagtagc cctggttcga ccgtcagcag gggagccctg
    12541 gcgtccaggg cccctgtgcc tacccaaaat tcggtcgctg cggcatgcgt gcgtcaaagc
    12601 tgcgtcaaaa cgcgcgtcat gacgtgagcg atgcgcatga cgagccgctg gatcctctct
    12661 tccatttgat tgaggtcgaa attacgcccg cctcagacgc ctcaacacct ttctgcctgc
    12721 gtgtggacac tcccctcccg tcctgcgaac gcaggtaggc tggtgcagca cgcgcgcgtc
    12781 tacgagggtg ttgttggaag gagcgagact ctacgcagcg cggcgcgcgt accggtggtg
    12841 gagcccgaag acttcacgta gctctatcac ctcgactccg tgctccgggc cctccacctc
    12901 acgcgtctcg ggcgcatcct tcccgagcga caggtgcgtc cggctcgcgt tgtagtagcg
    12961 ctggtactcg cgcagcaggc gccgagcgcg gcttcgttca ggacgacgac atggtcctgc
    13021 agttccctac gtatcgagcc gatgactctc tccgcatagg agttctgcca cggacaccgc
    13081 gcagcactcg gcacctcgcg aatccccaaa tgggcaagcg tggctcgaac gccctcggaa
    13141 tagagattgt ccccatctcg gtgcaagtac ctcggagcgc tggcccaggg aaaggcctct
    13201 cgcaactgct gcttcgtcca ttcctccgtc gggtgcgctg tcacattgag gtggaggatt
    13261 cgcctgtccg gtgactcaca accacaaatc ccaacagcac tccaaacgtc gcagtgggca
    13321 tgacaaagaa gtccatcccc gcagactccg ccagatgtaa gcgcaagaag ctctgccatg
    13381 agggcgctgg cttcggcgct ccccttcccg gactgggcat gtaccgagcg accgtttctg
    13441 gcctacctcc atccccagct tcagcaactc tccgtgaatg cgtggggcac cccatgtcgg
    13501 gttggcttcg gccatgcgcc gaatcaacac gcgcagttcc ggagttgccc gaggccaccc
    13561 tgtccgacgc cgggacttcc agcgccagaa gagccgaaag cccatccgat gccacttcac
    13621 caccgtcgct ggctgcacca agcacagtgg ccttcaccac ccctgccaga ggcgatggag
    13681 aacaccccag aaaaggcgtt cgcctcgggg acgggcgcgt ctcacggaag actgcgagtt
    13741 gctggcgaag agccaggttc cccagcgcca gctccgaacg gctccgcagg gccgagagca
    13801 tcgtctcgac cagcgccttc acgaagcccc gcatcgtgcc attcttgccg accgtagcag
    13861 gcaggccaga agtctggcgc gctctgtcat gagccgcctg acgccccaga gacagtcgcg
    13921 cacactcgcc gccccttctg gccccagcat gcagtggggt ccctgcgcta ttcagaaccc
    13981 cattcgcagt tccgtgcatg caatgacgcg ttcgctgacg cacgcgggca ctggacccga
    14041 atttctggca gccacaggct ttacgccggg aagaaccctt cggcccccac tgccgtatct
    14101 gtgagcgact tcgttcttcc cgcgtggaag acgaaaaaag aggaccggat tatcgacgaa
    14161 ggcgtcatca cgccgcactg ccgagggtgc cgcatgacga gcacgtcgac cgcctacgac
    14221 ttcgatagtc cagccgacct ggccccctcc tacctccaca cagtcccctg ccagacaggc
    14281 caccggatgc cacacgcaga gcagacgctc cgaaacttcc ggaatagcgg cgcgcgcgca
    14341 ttcctggcgc agcgctacga cctcgcgaac ctctgctcgc cgtgagctga cgagcgcgat
    14401 ttcgactccg tgcagttcgg gtcgcagagg actgaggaag gtacatgaag agggcgggac
    14461 caccctcttg cctccagccg gacgctcacg tcgtcaatgg gcctgacttc tgttggagcc
    14521 cctggatgcg aagtgccgcc tgctcctggc tacggcgcag gcatccaggc cagacccaag
    14581 ttcctgctgc tgcccgagtt tacgtcctgg atatcgctgc cgtcggccag attggcgctc
    14641 cggagcactc cacccagcca atccacccaa tacagccgcc cggccgtggc atcgatggca
    14701 atcccgtgca ctgtggtctg gttggtcacc agggtggtgg cgttggagcc gtccagatcg
    14761 gagacataga tactgttgcc gcgggtcgag tagtacacct tcccgccgct cgggtcgacc
    14821 gccaggccca cccccaggcc gcccaggcct gaagcgaggg tctccaggtt ggtaccatcg
    14881 agattgaatc gcacgagact ggtgttgtta taggtaatta catacatctt gtcattcggg
    14941 atatcgaacg cgatggcaga cgggctattg atgcccccga cgacctgcgt tggattgctg
    15001 ccgtccagtt cggcgcgcat gatccgttct ccgttgaaat cggaccagta cagcctgcgg
    15061 ttcgtcgaat cgactgccag cgcgctgggg tagcctccgt ccgccacgac atcgaccgga
    15121 ttcgccccat cactggccgc tcggacgatg gcgctgtcgc gcgtgtagaa gatggtacgg
    15181 gtgaccgggt cggtggcgac gaaaccggcc ccgctgatgc cagtcttgag ctcaatggca
    15241 ttcgtgccgt tcacgtcaac cctccacagc gagccggcgg tcgtgatcca gtagagactc
    15301 gcaagaccgg tgacgtcgac cgtgaaggtg gtggaggtgg tagcggcgcc gtcactcacg
    15361 gagagggtga tggtggtgga gccgctggcg ctggcgacag ggacgacgtt gaggatgcgg
    15421 ctggagccgg agccgccaag gatgagatgg ctggggtcat tgggcaccag gtctgtattg
    15481 gaggacgtgg cggtgaccgt gaggctgtcg gcggcggtct ccacgtcgcc cacggtgaag
    15541 gccaggtcgc cggtcgagct gccagcagtg atgctctggt tggccacggg ggaaatggta
    15601 gggaggtcat tcaccgcggt gacgtcgacc gtgaaggtgg tggaggcggt ggcggagccg
    15661 tcgctcaccg agagggtgac ggtggtggta ccgctggcgt tggcgacggg aaccaccttg
    15721 agggtgcgac tggtgctgga gcctccgaag accaggtttg tgggggcgtc gggcaccagg
    15781 gcggtgttgg aggacgtcgc ggtgaccgtg aggccgtcgg cggtggtctc cacgtcgccc
    15841 agggtgaagg ccaggtcacc agtcgagctg tcctcggcga tggtctggtt ggccaacgag
    15901 gatagcgtgg gcgtgtcgtt cactggggtg atggtgatgg tcaccgtgcc ctgggcgctt
    15961 tggccctggc ggttggtggc acgaaagatg agcgcatctt cgccattgta atcggcgccg
    16021 ggggtgtagg tgacggagcc actggcgctg atatcactca atgtgccgtg gtccggtgcg
    16081 tcgacgatgg tgaaagtgag tgcctcgttg ccggtggccg gcaggcgcag attgaggggc
    16141 gtgtcttcca ccgtctcaag cgtgatgttg cgggtcaccg gcgggatgct gggcggctcg
    16201 ttgtcccgac aagcggcgag ggtgctggcc gccagtccaa gcaccaatcc agcgcgcaat
    16261 gcggcgactg gcgctgcgag ccatctcgaa agcaaatatg acatgacgtt tcctcgtggg
    16321 ggtgcccgat atgggcagcg taaacgcgga gcgccgggtt ctccgctgac gctggccgcg
    16381 ctgtcaatcc tcatttgtcg acttgttcgc gctcatatta gtgcgaatag tggaccccaa
    16441 accgcagcac ctgtgcctat ccaaatccgg tcgctgcgtc atgagtgcgt caaggccaca
    16501 ttcggcagtg cgtcaaggcg agtgagcgag acgcgcacgg tgccgaatgt ctctgccctg
    16561 gtggcttacg gcgaggacga ggacaggcac cgacacctgc tggacatcca ctggggcagc
    16621 gagtcggtgg agttcctgtc tgggactgct gcacctgctg ctcaagcggg actgacgggc
    16681 atccgactcg tcatcgccga tgagcgcgcg gggctggccg ctgtggcacg acggatgtta
    16741 atcagaagct cagttgctgc gcttcacggc gcacctcacc ggaacgccct cgccaaagcc
    16801 ccctggcggc tgcgaggccg gctcggtacg gagacgtcag ccgcccttcg gactcccagc
    16861 ctccaggagg ctccaaagca ccaggaggcg ttccaaaccg gcctgggccg ccaggtgtcg
    16921 aggccatgga gtgtctgcgt gagggcttcg ccgccgtcac ttacttcttt gccttcccca
    16981 gccccctgga agcgccttca caaatccatg gcctggagca actccacggc gaggtgaagc
    17041 gtcgcatccg cgctgtcggc gccgtactgg accgcgccag tgcgctgcgc ctcatcaccg
    17101 ccatcgtcat tgaagtcacc agcgtctgga atgaccgccg ctaccgcgac atgtccctga
    17161 tgagctcagc cccagatacc actgctgctg gatacctccg cggtgctttc cgccctgggc
    17221 ccctccgaac caactacaca ggattcggaa ttgccccggc ctctatccga gtgacgcagc
    17281 gccggcgcag ggcgccccaa cagcgccatg ttctgagcga ctcccaaacg cgtgatgccc
    17341 taccttcgtg ctggctggaa tctggaggtg tgcgccgaag gcactggagc acggtgcacg
    17401 tcgtgtcata cccccacagc caggttcacg ggaggaggag cttgtcgccc ccctcggctt
    17461 cgagttgcag tacgcgcgca agagccggcg acgcctcatc cggtctcctg ggtactggct
    17521 ggttcgctca cctactcccc gaaaggattg agcagttcgg ccagcttctt ctcgtacccg
    17581 gccacatcga taaatggctg gagggacttg acgtgcgagt agctgttgaa cttctggagt
    17641 agcgcattcg cggtggagag agagagtcgt tgtccacgcc cgacagcagc atcaggctgg
    17701 gatacaactt ctggaagcgt gtcgtgttcc aggtgatggc tttgtccagc gagtcgttcc
    17761 acgcattgta gtcggcactc gtccccgcct ttcctccaat ctggaggatg accgtgctcc
    17821 cctgtgccta ccccaaattc ggtcgctgcg tcatgagcgc gtcgaggatc cggagcccca
    17881 gcccgagggc atgtattcgg atgacgagac gacccggaag acatgtaccc ggacgacgag
    17941 gaggagccca agccgcgcgg ccgttgaggt atagctgccg catgacgtcc tctcctcccc
    18001 cgggcgcggt cgcattcgtg gaccgctggc gcgagctgtt cgatgcctgt gactggtccg
    18061 gcctgcgggc gcacgagcat cccgactttc ccgaggccgg ccctccccgc cagaacgaca
    18121 gcttcatccg cggactcggc aagagcagct ttcaagtcac gagcgcgacg ctgaagccct
    18181 tcgtgcagcc ccggtggtcc atcttccgca cgcagcgcct gcacccgcaa ccgacgtatt
    18241 ggtgtgacct ggtgttgaag aacgcgaagg gccacgagac cgaggccttc atcgccctgg
    18301 ctccatggga gggcaccgag ggcgccttcc gcgcctcgta ttacgtcgag attcccccga
    18361 agaagaaggt cgccccgttg gacttgggca aggagcgcca gcgcgtcgcg aagttcctcg
    18421 ccaaggcagt aaaggacttc gcccgggtcc aggacgcacg gccgctccaa cgactggagc
    18481 tccagtactc caccgacaac gggacgctga acgtgagctt cgacctcgac ccggcggccg
    18541 agccgggacg tggcgacgcg atgacccatt tcggcttcgc ggagctcctc gtcccgcgct
    18601 gggccgacat gaaggagcac aggccgtccc tggtgggcct cgatggcgcg aaactcgcgg
    18661 cccgcgagga tgggacctgg ggcacgcccg aggcgcacgc gcaactcgag gagcacttgg
    18721 ggaagatgct cgtcgcgacg ctgctcgaga tgcgggacag cggccagttc gaggccctgc
    18781 gcgcctcggc caccgcggag ctgggtgtcg aggagcacga aggccacttc ggctggcccg
    18841 actacgagga gcgcaggcgc gagaacagga ttgcgtcgtc cccgtagcgc cgcgcgtgga
    18901 ggcacggctc ggatgccccc gccctctggg cgatgaaggg ggactccacg ccgccggtcc
    18961 gtggcccgag ttcgctgggc cacgcaacat gcagccgcga gttggggcag cggcaacctg
    19021 gcgcggccgg ctcgacaccg cccggggagg ccgtggacgc tggccggacc ggccgcgatg
    19081 ggccacgggg ccacctggac gtggttaaca gctttgttaa ccatcaaggg catccgattc
    19141 tgacaatccc gggctttcga tgtcacacct tccagggttg cgtcgtttcc ctctttcaga
    19201 atgacgaatc gggcgacctg ttaaccgaga gagcgaagcg cggttagcct ttactgggta
    19261 ctcacgattt cgttgcgcgg cacagactct cagagacggc tctcagactg tctcggccgc
    19321 gcttctcgac cggcacagcg ctacccccgc cgcgctgctc ttctccacgc ggggccagtg
    19381 ccctcgaatt ggattccgga ccgagaagac agtccgagga cacgcccgcg ctgacagcca
    19441 acatgaggag cgagtgcact gctcatcgca tcttgagcac cactcggaag cgggcgtggt
    19501 tgctcatcat tcgctcgaag gcctcgccag cgcgctccag gggaaacacc tcattctggg
    19561 agcgcacacc cgtgagcgcg ctgaagtcca tggtgtcctg cgagtcctgg ggaatgccgc
    19621 tgggccagcc ctggacgcgc tggcgcttca tgatgagttg ctggctggtg acgggaatag
    19681 gctccgcgcc cgcgcccagt aagagcagga cgccgtcgcg gcccaggccg ccaatcatgt
    19741 ccgccaccag gctgttgctc gacgcggtca tcatgatgac gcgcgcgccg cccagggcct
    19801 ggagcgcctt gcccacctcg cccttctccg tgtcgatgta ttcatgggcg cccagttccg
    19861 tcgccagctt ccgcttgtcc gccccgcgcg agatggccac ggtgcggtag cccaacttgc
    19921 gcgcgaactg gatggccagg tgccccaggc cgccaatgcc ttgcaccgcc accagggagc
    19981 ccggcttcgc gcccatgttc cgcagggagt tgaacgtcgt cacgcccgcg cacaagagcg
    20041 gcgcggcgtc ctcggacttc ataccgtccg ggactcgggc cagggcctcc tggggcgcga
    20101 gcatgtattc ggcgtagccg ccgtcgtagc tgatgccgca gatctgctgg aagtcacagg
    20161 tgacgaagtc gcccacgcgg cacgcggggc actggccgca gtggcccccg tgccagccca
    20221 cgcccacgtg ctggcccgcc ttccacgccg tcaccccggg ccccacatta tcgatacggc
    20281 ccaccacttc atggccgggc acccgcgggt actgaacggg catccacccc tccttggtaa
    20341 tcgcatcgct gtggcagacg ccacacgcgt ccacggcgat gagcacctgt ccggagccag
    20401 gctcgaggac atcccgcccc acgacttcga gcgggccctt cgcctgcttc acctgcaccg
    20461 ccttcatctt cctggccatc gcgccctccc ccatgggtgt gaagaacgca ggtgaatatg
    20521 ggcaggcccc gaagtgaaga cgacaggcca gatggagttg aggcggcggc cgtgcgggcg
    20581 gccgcctcca tgccggtgtt gctccgtggc gggtgagggt ggcagggacc ggccacggcg
    20641 aatgggccgt cgcccctcag acggcagaga gtcgagcgct cccgcgacct ccgtgccctg
    20701 tgcctaccca gaattcggtc gctgcggcat acgtgcgtca aagccctatt cggcagcgcg
    20761 tcaatgcgag tgagcgacat cctggcgcga ctatcgccag tcgccttgtc aatcacaaat
    20821 caagacatga gagacgagga aaacagagaa cctattgcac atcccgccga gcgatctcca
    20881 agaagttatg aacaagggcc gaacggctgg attttgggta aacaagagca agtcgtgcaa
    20941 ccggccgtgc gtcgctgata tctcggtagc tgacgccctc cagggcaagt tgacgcattg
    21001 acgccgggac gattgaaacc ccctggccag ttgcgacgag cgaaaggacc gatgcgattt
    21061 gcggtgcgga ttgtcccacg cgcagctcga agccagccgc agcgcaagcc ctcactgcgg
    21121 cgtcaaacaa atctgggccg ttcattctcg gcgtgaggat gaatagctcc tcacgcaagc
    21181 ttgcgagggc cacagggccc gaggccgcca tgggcaacgc ggggtgtcca gccggaagcg
    21241 caacaaccat cggctcatcg ggccatgaaa ctacgttcat ctcaaccgtg tcgattccag
    21301 aggggcgcat aaacgcgagt tcgagactcc cctcgtgtag tgaggcccca agagacgcgc
    21361 tgttattctc attaagggtc agctcg
//
