LOCUS       NZ_CP040829            26435 bp    DNA     circular CON 23-AUG-2024
DEFINITION  Paenibacillus polymyxa strain ZF129 chromosome, complete genome.
ACCESSION   NZ_CP040829
VERSION     NZ_CP040829.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5703931)
  AUTHORS   Li,L., Li,B., Xie,X., Chai,A., Shi,Y. and Xu,S.
  TITLE     Complete genome sequence of biocontrol strain Paenibacillus polymyxa
            ZF129 and further analysis of its biocontrol mechanism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5703931)
  AUTHORS   Li,L., Li,B., Xie,X., Chai,A., Shi,Y. and Xu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2019) Institute of Vegetables and Flowers, Chinese
            Academy of Agricultural Sciences, No.12 Zhongguancun South St.,
            Haidian District, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1092.65x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_006274405.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:29:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,145
            CDSs (total)                      :: 4,988
            Genes (coding)                    :: 4,933
            CDSs (with protein)               :: 4,933
            Genes (RNA)                       :: 157
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 33 of 55
            Pseudo Genes (incomplete)         :: 26 of 55
            Pseudo Genes (internal stop)      :: 10 of 55
            Pseudo Genes (multiple problems)  :: 13 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:14:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2177101
            Orig. end                         :: 2203536
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040829.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26435
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="9"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26435
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26435
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16435](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16435
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            158..991
                     /locus_tag="FGY93_RS09575"
                     /old_locus_tag="FGY93_09575"
     CDS             158..991
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373634.1"
                     /locus_tag="FGY93_RS09575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09575"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_016822702.1"
                     /transl_table=11
                     /translation="MYKLKRLLANTIKYGALLLGAFIALLPIVVILFASLKTKAEYAAT
                     SPLTPPVNWLNWANYAKAFVDGNMLTGFLNTAFILLISIIGATLTGSMIAYILNRFKFK
                     GKSLMLGAFLLATLIPGVTTQVSTFQIINKLELFNTPWAAILLYLGTDIIAVYIFLQFL
                     DSIAVALDESAMLDGASYLTIYWRIILPLLKPAIVTVIIIKGVNIYNDFYTPFLYMPKT
                     SLQVISTALFKFKGPYGSQWEVISAGIIIAIIPTLVAFLSLQKYIYNGFAQGSVK"
     gene            1034..2083
                     /locus_tag="FGY93_RS09580"
                     /old_locus_tag="FGY93_09580"
     CDS             1034..2083
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822703.1"
                     /locus_tag="FGY93_RS09580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09580"
                     /product="glycoside hydrolase family 130 protein"
                     /protein_id="WP_016822703.1"
                     /transl_table=11
                     /translation="MSKLNVDLDVGNVRIVGDSLSKMPWQDKPEGSEAPVWRHTENPVI
                     GRNPVPGIARIFNSAVAPYEGRFVGIFRAETINGRPHLHLGWSDDGLAWDIETERLHMV
                     DEEGNEYQPNYAYDPRLVRVEDTYYIIWCTDFYGAALGIAQTKDFKSFVRLENPFLPFN
                     RNGVLLPRKLNGNFMLLSRPSDSGHTPFGDIFLSESPDLVYWGKHRHVMSKGGQGWWQS
                     VKIGGGPAPIETTEGWLMFYHGVTGTCNGLVYSMGVAVLDLDDPSKVKYRSSNFVLTPE
                     EWYEERGFVPNVVFPCATLHDADTGRIAIYYGAADTYVGIAYTTVSDIMKYVIATDEVV
                     ADDRESGRM"
     gene            2096..3055
                     /locus_tag="FGY93_RS09585"
                     /old_locus_tag="FGY93_09585"
     CDS             2096..3055
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373632.1"
                     /locus_tag="FGY93_RS09585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09585"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_016822704.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-06, bitscore:
                     27.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.5e-11, bitscore:
                     41.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEDMSLQQLQSYMGSNPKPQDFDMYWERALQELERQPLEYTLEP
                     AEFVSPLVECYHLYFTGVGGARVHGKLARPKHLTEQGPALAMFHGYSCDSGDWFDKVSY
                     AAHGFTVLAMDCRGQGGLSEDNLQVQGTTVRGHIIRGIDDPDLDRLYYRNVFLDTVQTV
                     RILMSMEQVDPERIGAFGCSQGGALTVACAALEPRVRVAVPVYTFLSDYKRAWALDATT
                     SAYEELVYYFRWFDPNHVRESEVFHRLGYIDIQHLADRIRGRVLFVTGLSDVICPPSTQ
                     FAVYNKIVSDKELLVYHEYGHEYLPYLSDRAMSEFLRL"
     regulatory      3111..3210
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            3279..4457
                     /locus_tag="FGY93_RS09590"
                     /old_locus_tag="FGY93_09590"
     CDS             3279..4457
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688926.1"
                     /locus_tag="FGY93_RS09590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09590"
                     /product="MFS transporter"
                     /protein_id="WP_016822705.1"
                     /transl_table=11
                     /translation="MNFKVVILTIATFTVGLVELIIGGVLPQIAQDLNVSVSTAGQLIM
                     IYALVYAIAGPTLLALTAKIERKRLYLWSMFIFILGSLLAFWSPNYAVLFISRIITAAS
                     GSLIVTLSLTIAVKVVSKAYQARVLGVISMGVSSSIVLGIPAGVLIGNAFGWRVLFLII
                     ALLTVVSMIIMHLFMERIPTEHVVPMREQLKSLKNVKVISAHLVTTLTLAGHYTLYAYF
                     TPFLENLMGLNASWVSVAYFVFGLAAVSGGFIGGSLADRFGTAKSILIVVGVFIAVMFL
                     LPFSIHSVYMFAPLLIIWGILSWALSPPMQSYLIENAPESSSIQQSFNFSALQVGIALG
                     SALGGVVIENSESVATNAWVGGAFVIVAFVCGVFSITRAGTSQTVRGHHSVS"
     gene            4538..4681
                     /locus_tag="FGY93_RS25860"
     CDS             4538..4681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432937.1"
                     /locus_tag="FGY93_RS25860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RAxF-45 family protein"
                     /protein_id="WP_016822706.1"
                     /transl_table=11
                     /translation="MNHEMLNNRISQLPIAMAGIVHAFPYNGRSLSNFNHTVVNIARRR
                     LP"
     gene            4785..6869
                     /gene="abc-f"
                     /locus_tag="FGY93_RS09595"
                     /old_locus_tag="FGY93_09595"
     CDS             4785..6869
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="abc-f"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822707.1"
                     /locus_tag="FGY93_RS09595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09595"
                     /product="ribosomal protection-like ABC-F family protein"
                     /protein_id="WP_016822707.1"
                     /transl_table=11
                     /translation="MYIVNGQQLKKYHAANLILDGATFDIHKGEKVGLIGRNGSGKTTL
                     LRLIARLSHPDEGQLVIAKDTRIGYLPQIPAEFESFTVYETLAYAYRELKDCRNQMATL
                     EREMSDPVVAANPELLEKLLQTYASLQERFERNGGYEMDASMDQIADGLGIPKAMYTRN
                     FGSLSGGEKTKIALASQLIGRPDLLLLDEPTNHLDLKGLEWLEQFLQGYAGACVVVSHD
                     RYFLDRVAGKMIELEDGEAFTYYTNYSGYVKEKEERLLLQFEDYKEQQKRIKKMRETIR
                     RLEEWGRNGDNEKFFKKAASIRKALERMELVKRPVLDPQGAEFHLKLEDRSGRRVLQFE
                     DITKAYGERQILNEATGSLEFGEKVALLGNNGAGKTTLLKLLLGQESVDAGTVQWGARV
                     EYGYLAQQERERDSRATVLAYFKEEAGLEEGEARGQLAKYLFYGADVFKPVSMLSGGEW
                     SRLRLALLVMKKPNLLVLDEPTNHLDIDSREALEEALGTYTGTVLAISHDRYFVNKLAG
                     RVWELENGKLSFYLGGFDEYRAKKRELENAHSQRGADAGVRSASAGRAASGGGSGAGLA
                     TPASAASNDAGTAARTGATTGADASRARSGAAGQLGAPDARSGARGAKVAKPSRSPAVS
                     RERLERAIAAKEAELAATDAELELLGTSSDTARMAELWDVRERLQAELDTLLGEWVELE
                     "
     misc_feature    7019..7028
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     misc_feature    7059..7071
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     misc_feature    complement(7073..7089)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 26.05"
                     /tool="antismash"
     gene            7322..7498
                     /locus_tag="FGY93_RS09600"
                     /old_locus_tag="FGY93_09600"
     CDS             7322..7498
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038155.1"
                     /locus_tag="FGY93_RS09600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09600"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_113050054.1"
                     /sec_met_domain="TIGR03731 (E-value: 8.2e-08, bitscore:
                     30.3, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAENLFDLDIQVNKSQGSVEPQVLSIVACSSGCGSGKTAASCVET
                     CGNRCFTNVGSLC"
     CDS_motif       7322..7387
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAENLFDLDIQVNKSQGSVEPQ"
                     /locus_tag="FGY93_RS09600_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7388..7498
                     /prepeptide="core"
                     /locus_tag="FGY93_RS09600_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="11.80"
                     /molecular_weight="3323.8"
                     /monoisotopic_mass="3321.5"
                     /core_sequence="VLSIVACSSGCGSGKTAASCVETCGNRCFTNVGSLC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAENLFDLDIQVNKSQGSVEPQ"
                     /leader_location="[7321:7387](+)"
                     /alternative_weights="3341.8"
                     /alternative_weights="3359.8"
                     /alternative_weights="3377.9"
     gene            7668..8396
                     /locus_tag="FGY93_RS09605"
                     /old_locus_tag="FGY93_09605"
     CDS             7668..8396
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312511.1"
                     /locus_tag="FGY93_RS09605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09605"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_045244713.1"
                     /transl_table=11
                     /translation="MTDFLLEVKQVSKTVGKRSLLNNISFELEKGKIYGFIGPNGAGKT
                     TMMRIMTGLMQPTSGSVKIASYNIQTDREKALSKVGAIIESPVFFDYMTGRQVLRNLSR
                     LHLGVASSDREKHIKELLERVGLENRGDDKVKTYSLGMKQRLGIAQSMLGNPELLLLDE
                     PSNGLDPMGMRELRDIILRLRDSDNYAFFVSSHLLDELQQMCDELIVIKEGTLIWKGAA
                     DQLIKDGQRLEDAFMGLMGL"
     gene            8393..9193
                     /locus_tag="FGY93_RS09610"
                     /old_locus_tag="FGY93_09610"
     CDS             8393..9193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312510.1"
                     /locus_tag="FGY93_RS09610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09610"
                     /product="ABC transporter permease"
                     /protein_id="WP_044786940.1"
                     /transl_table=11
                     /translation="MKTLVYSEFERLWRRKWFWLLVLCTPVLVYSTGIYIQHTLRIPVK
                     DLSKIFIVAGLRENLYLICNFAVATLVAAVFTEEFRSGQLRLLFVRRFTRGQIFWSKLL
                     VVNTSILLLLIVYAVSSQVIVVFWKFSHNINGTDIFGQIWSQVFEYYGWAFASLLAISS
                     LYSFIAMCSKSVTYAIGICMTYNLGVLLFDPLYMKLATLFSSIPLLKNLIPFLLIPYLQ
                     YKGLDQSLIWNWSVNGAIVIAVLFHLILFTGWAYRRFTTDDYLY"
     gene            9206..9973
                     /locus_tag="FGY93_RS09615"
                     /old_locus_tag="FGY93_09615"
     CDS             9206..9973
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312509.1"
                     /locus_tag="FGY93_RS09615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09615"
                     /product="ABC transporter permease"
                     /protein_id="WP_090888938.1"
                     /transl_table=11
                     /translation="MSGIWLSELERIWNRKSTFLLYIAMLLIIFVNIWSLKTNGTMRFR
                     FGEGTVVVNNLNLPWLMMSEISLFLILAMLPILYVDQLGGDLHSGAYRLYVLRPYRRFQ
                     FWLGKLLALSVTTAIFTGTALVIGIVAGWLLFPHTSTFFKYGSGVISPSSDAIPYTLAF
                     YLILTLACVAKLLLVSAVCLFISRPLFAFIAIFVLSVALYQVVRPLVLLMDPFQQIMLA
                     LRVEGSFKFWMCLIAIILVGSVISFVRWQKKII"
     gene            10001..13177
                     /locus_tag="FGY93_RS09620"
                     /old_locus_tag="FGY93_09620"
     CDS             10001..13177
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="FGY93_RS09620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09620"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_045244711.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.3e-176,
                     bitscore: 586.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.8e-12,
                     bitscore: 46.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.5e-35, bitscore:
                     119.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTTGNLYKTLDFFMLRTPVLPIQEFSKCFPSSIKEGGDAREIAL
                     ERLLELSRDPFIREALAASSPTLLESLVHISNHENPRKQGQVIKAFMRYIIRMITRPTP
                     FGLLSGITYGRFGERSQLFLQGTDTFKKRARPDMEWLMKAVELVESRKEIVRQLRVRSN
                     KLIYRQGNRAKIPYTTRHGSMNDGEDQSVSVRITQVFDCVMAASSAFIPFLDLVDHLNK
                     TFESANIEVIERYVWQLFEQEFLISELIPPTTTTEPLSYIRSVLKPVTGIEELKEDLDT
                     IADTSAKYNHLPIGQGEQLLESLRQKMNKMFSAKSSLQIDLSLEDRGIILPQSIRKDIE
                     CVAELLTKLSTRENRPLNEFCVEFLEKYGPYREVPLLDLLDEDTGLGAPAGYKHPMSRR
                     VRLQDMSPSKSRSHQEKLLFQWFVSAMHEGKHEIVLTDNMIDELIKGHDTEKWLAAPSM
                     ELFFQLITSDQEALDQGEYTLLLAPNQGSDAAGKTFGRFMDLFGEPFNDIFSSIQSEEQ
                     RLQPGKLLAGISYLPSSGRSANVVLTKQTRPYEIAIGANHTMPEDRQIHISDLVVGVRN
                     DHFYLKSKSRNREVIASSGHMLNAELTPNIYRFLVEVSDNSYRHWSPMEWGFVAHAPFT
                     PRLRYKHIILYPGTWRIASSSSKKMADFAEEIRLFQEKWNIPRYVYMIESDNRILLDMD
                     HPLHIEQICRDLQSKGKVTLIEHIGGLDNSPVSCGKGHLTAEFVCPLVRNQAEDTQHFV
                     EETAASLELVAKENEQQPTKADYTYLPGESWFYAKLYGINSRQNEFIGGYWEEFVRKHQ
                     DNGTILQAYFIRYADPDKHLRVRFELSKNRTADGFLSTFHKWTEMLLHEGMIARVVIDT
                     YEPEIERYGGSKPMAWAERMFSCDSEVTAKLVHLIRFNQVSLEEDIIATLSVINLLYQF
                     GYHEKDAFNLLNRYFDVKEYLENFRKERKFFLQWFASDQEISQSIQSNLQAIESIFKIR
                     REAVKQYSHVLYEHETGGLSTNTREDIVFSVIHMHLNRLLGIDRDRERKIMIMARHALN
                     SLVQYRGNRQ"
     aSDomain        10475..10756
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FGY93_RS09620_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.00E-14"
                     /identifier="RREFam001.1"
                     /label="FGY93_RS09620"
                     /locus_tag="FGY93_RS09620"
                     /protein_end="252"
                     /protein_start="158"
                     /score="46.0"
                     /tool="antismash"
                     /translation="RVRSNKLIYRQGNRAKIPYTTRHGSMNDGEDQSVSVRITQVFDCV
                     MAASSAFIPFLDLVDHLNKTFESANIEVIERYVWQLFEQEFLISELIPP"
     gene            13174..15051
                     /locus_tag="FGY93_RS09625"
                     /old_locus_tag="FGY93_09625"
     CDS             13174..15051
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="FGY93_RS09625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09625"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_126666356.1"
                     /transl_table=11
                     /translation="MTDIQAKMNLESSTIWRSVRQGVKLFSLVFGMNKTYMVSSIFLHI
                     LQGLMPVLTLIIMQNLLNSIVSFGTQGISLIMLQFGIFIVIHVLKSVVTMSQTFVEGTL
                     ESVLSKSLNLMIGKKSSSLGLADYENSEINDQLKRASQEASYRPYQLYTQMAGILSSMV
                     TMVSSATLILLWKWWVVIILFGISLVSVYSIFKLNKEQFEIYMNRTPLYRESWYMTYLL
                     TNDRAVKEVKIFNMSSYLLKRYEDLLQRFFVEDRRILGKRVTITFMYSLLELAVLLGVV
                     WVAIRETFEKKILVGSLYGYIQAIMLTQSQMQALIQGIVQFSQNNLYMEQLFLFLQLPT
                     SDPVRQQKEQALPINRKKNEDFCIEQICIEGVSFTYSGKTVPSIRDIHLTVNRGQTIAI
                     VGKNGSGKSTLMKVLMQLYSNYEGVFKINGLPVQDYDLHQVQDKIGVVFQDFMHYEMSA
                     RHNIGFGSLERLEKDEELIQAARYAAIDQIITELPRGLDTQLGKWFEDGFQLSGGQWQR
                     IAIARAFLRQADIYILDEPSSFLDPVAERDLLKLFLELMKDSIGIFITHRISSARLADK
                     IVVMDNGGIVEQGTHRELMLLDGLYAEMYNIQASSFNDEEALAETGGRV"
     gene            15053..16435
                     /locus_tag="FGY93_RS09630"
                     /old_locus_tag="FGY93_09630"
     CDS             15053..16435
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="FGY93_RS09630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09630"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_180361608.1"
                     /sec_met_domain="LANC_like (E-value: 1.3e-55, bitscore:
                     186.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTISYTCDNWIPVKGEMKNKISTLLREITERYRNPDQVRLWMKK
                     IPPIEADGVIMERWADESLGSGFTGICLLMGQLDYLYPKNGWDIVGHQYLERIRMVVEQ
                     KGVHDLSLYSGLAGIMLAIYSLSRKGTRYQGMLDALASWFEEAALQSLALHRIEWEKGE
                     LRMSQYDTISGFAGVGRIAMLFLNRPGMQMVWEQTMDLFHVMCGEKNLNGHTVPAWHIS
                     SEHQFQEDEKLQYPQGNFNLGISHGIAGPLCFLSLSALHGVDASPLMNDIHRLGKFIHH
                     WRVQDVEGIIWPGRISFGEWLDGQLLSGSTRNYRDSWCYGVPGIARSIWLAGQAVHNEE
                     WLETGLSAYLDIEKRLHRKGGLSSATLCHGIGGLLHLVQRMYSDTSHEQLGRIRDRLLE
                     DVLDMFDANSLFGFYDHSLLDGRLAEVDEAGFLNGSAGVALVLASLIGDQNPEWDAAFL
                     IR"
     gene            16630..17862
                     /locus_tag="FGY93_RS09635"
                     /old_locus_tag="FGY93_09635"
     CDS             16630..17862
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822710.1"
                     /locus_tag="FGY93_RS09635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09635"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_126666370.1"
                     /transl_table=11
                     /translation="MWNGVKRLSALASILLLAIIVSACSKGDASGKVQIEFFQNKPEAK
                     DSFDKLIAQFNQEHPGIEVTQVNPPEAETVLLTRVVKNDVPDIVGLGATDTYSILAQSG
                     IFTDLANTELPRTVDPIYLKMLKDVTGVDPVYGIPYAANANGVMYNKTLFKEMGLQVPK
                     TWDELIATAQKIKAAGKIPFYFTYKDDWQTNLPFNALGPNLVGIDFFLQRRENQVTFQD
                     KYREVAEKQLELLKYGHSDNFGKNYADGNRAFANGQGLMYIQGSWAISEIRKANPKVEL
                     GFFPLPTGNDAKAVKLVSGIDTLLAVSESTPHKKEAEEFIAFLLKPENSKQYITEQTLF
                     SAVKGVTQDDPSVAELLPYFKSGRVIDFADHYIPKAVQLNSIVQAFLQNGDIDAYLAKL
                     DREWNKVANRR"
     gene            17879..18745
                     /locus_tag="FGY93_RS09640"
                     /old_locus_tag="FGY93_09640"
     CDS             17879..18745
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373624.1"
                     /locus_tag="FGY93_RS09640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09640"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_102997464.1"
                     /transl_table=11
                     /translation="MNKRLTTFYWMTVPAVLLFFIFLTLPALQGFYYSLTNWNGFGHQY
                     HFVGFKNYINLFQDDNVGNAYWFTFKFAIVVTIAINILSLLIAMGLNAKIRFRNFFRGI
                     YFLPNILSVLIVGYIFNYLFSNVFTIWGQNLGISSLSTNILGSEQLAWVGVVIVAVWQG
                     IAFNTILYLAGLQTIPTSLYEASNLDGAGKWREFWSITFPLIAPFFTINMVLAMKNSLM
                     VFDQIVALTNGGPGRATQSISHLIYTGGFRGGEFAYQSANSVIYFIVIAIISILQLRFL
                     QRREMDN"
     gene            18745..19569
                     /locus_tag="FGY93_RS09645"
                     /old_locus_tag="FGY93_09645"
     CDS             18745..19569
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426161.1"
                     /locus_tag="FGY93_RS09645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09645"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_058711061.1"
                     /transl_table=11
                     /translation="MKTSRRTNWPVLILVALGTIFILFPLYMTVTIALKNPEQMAHSAF
                     AFPTELHWENFSRAVEMTNFFSAFQNSVMVTTSTVILTLLTNSMVAYAIARNMQRRFFK
                     GLYFYFVSAMFIPFPIIMLPIVKLASGLHMTNLLGLIVLHTVYGLAFNVFVYVGYIRSI
                     PVALEEAATVDGATTWGTFWRIIFPLMAPISATVGILTCLSTYNDFLLPLIIISDAEQY
                     TLPLVQYVFQGQFNTDFNLAFASYLMALLPMIIVYLIAQKWIINGVTQGSVK"
     gene            complement(19680..21365)
                     /locus_tag="FGY93_RS09650"
                     /old_locus_tag="FGY93_09650"
     CDS             complement(19680..21365)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688920.1"
                     /locus_tag="FGY93_RS09650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09650"
                     /product="DUF4179 domain-containing protein"
                     /protein_id="WP_126666357.1"
                     /transl_table=11
                     /translation="MNNVEKALKRKLNEDSEIAYPDFNEMWNRMEQAGYTAPTLTDASD
                     SFTPHRHSNWRKIAIAASLSALLVAVPVYAAIHYNWDNLLHGRSGIETALAQNLGQPLE
                     QSVTRDGIKLTLHTAIVDENRTVILYSLEVGKRTDNEFWNVKGVSLKNAAGKSSEGEYS
                     FQQWDEKNQRYNGYFESDWTPQQETENVRLTVDHVELTSVQELDLPLDIKSPQTQTFKL
                     DRNGLQDMKVQVFEQGKDKLMLSSAITFDSSIPKEWDNPQIIAYKDGKPVNPQSGGTFG
                     TPGENGEYTAQQYFTKEDIPEGQTTFKLQYAQTEKSIHEPLKFDLQLSKKKMESGTIKS
                     VLNTPLENGNPNFMLEQMIVTPTQIRVTIRSKEKFAMLPYQKYFLSVNGTTLEGSRWSS
                     PDQEHDLNTIRFERPANLVITKDTPITFTGKYKVTTHSDDKTPQRLADISEQKQTLTTQ
                     IGGYPVKWTYYKQGADLFVETESEDTHFGGINQTHIGLGKERIIGKPITANFAGDGNNK
                     AVDVYKNFKGKEASIYMFYYTTDDPEAETTVPLQPLTSNSKVSK"
     gene            complement(21325..21885)
                     /locus_tag="FGY93_RS09655"
                     /old_locus_tag="FGY93_09655"
     CDS             complement(21325..21885)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373621.1"
                     /locus_tag="FGY93_RS09655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09655"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_126666358.1"
                     /transl_table=11
                     /translation="MQSNRELFDLYQRDVYRTCYYMVHNASDAEDLTQEVFITLFRSNR
                     EHIKQLKAWIMKVTVNHCLNHLKRRKSLHLKVSANLHLFTGTESKSVDRQVEERESAEE
                     WAVYMNRLPAKIRAVLTLRYMHDFTLVEISKLLEIPLGTVKSRTHKGLKLMEQILREAG
                     TQFPEMEGENYEQRRKGIEAQVK"
     misc_feature    21850..21863
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: strong, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(21981..21997)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 24.15"
                     /tool="antismash"
     gene            complement(22142..23149)
                     /locus_tag="FGY93_RS09660"
                     /old_locus_tag="FGY93_09660"
     CDS             complement(22142..23149)
                     /EC_number="1.3.1.95"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (22-198). E-value: 3.5e-26.
                     Score: 84.0. Matches aSDomain:
                     nrpspksdomains_FGY93_RS09660_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312503.1"
                     /locus_tag="FGY93_RS09660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09660"
                     /product="acryloyl-CoA reductase"
                     /protein_id="WP_126666359.1"
                     /sec_met_domain="ADH_N (E-value: 3.6e-05, bitscore: 21.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.8e-13, bitscore:
                     46.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQSFQALVVDQTHDGEVQAEVRSLKTDNLPAGEVLIRVAYSSIN
                     YKDGLAARKDGNIVKSYPFVPGIDCSGTVVSSEDSRFSEGQAVLVTGYGLGVSQFGGFS
                     QYARVPADWVVPLPDGLTLREAMIFGTAGFTAALSLYRLEQNDVAPEKGKVLVTGATGG
                     VGGAAIALLHKRGYHVVASSGKVESHDYLKALGAADVISREEVYDGAESIRPLAKQLWQ
                     AAVDPVGGKPLASLLSQIAYNGSVAVSGLTAGTKLPTTVLPFILRGVNLLGIDSVFCPY
                     DTRVAIWKHLGSDWKPEQLEQLVEREIGLADLPSALEDILAARSQGRTIVRLAD"
     aSDomain        complement(22556..23083)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGY93_RS09660_PKS_ER.1"
                     /evalue="3.50E-26"
                     /label="FGY93_RS09660_PKS_ER.1"
                     /locus_tag="FGY93_RS09660"
                     /protein_end="198"
                     /protein_start="22"
                     /score="84.0"
                     /tool="antismash"
                     /translation="RSLKTDNLPAGEVLIRVAYSSINYKDGLAARKDGNIVKSYPFVPG
                     IDCSGTVVSSEDSRFSEGQAVLVTGYGLGVSQFGGFSQYARVPADWVVPLPDGLTLREA
                     MIFGTAGFTAALSLYRLEQNDVAPEKGKVLVTGATGGVGGAAIALLHKRGYHVVASSGK
                     VESHDYLKALGAA"
     CDS_motif       complement(22637..22690)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FGY93_RS09660_0001"
                     /evalue="3.70E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="FGY93_RS09660"
                     /protein_end="171"
                     /protein_start="153"
                     /score="16.3"
                     /tool="antismash"
                     /translation="KVLVTGATGGVGGAAIAL"
     gene            23505..24914
                     /locus_tag="FGY93_RS09665"
                     /old_locus_tag="FGY93_09665"
     CDS             23505..24914
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312502.1"
                     /locus_tag="FGY93_RS09665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09665"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_064961582.1"
                     /transl_table=11
                     /translation="MTTRALKNGSVLSEAKELNLFRLTWPIFLELFLFMLMGSVDTFML
                     SSVSDNAVSGVGASNQIISIAILVLEVIGNGAAIVVAQYIGSKKLVEAAQVTGTAITLN
                     LMVGLLLSVIFLVFGTHMLQWLNVQGDILTYAESYMSIVGGAIFLQALINSLAATIRTH
                     GFTKETMYVSVFMNVIHVVGNYVLILGHWGMPALGVEGAAISTVGSRFICLLIFFWLMY
                     RVTEVRVEWKYYVHLSRKFITKILRIGVPSALESIMYQSCQLIFTLYVTYLGAEAMATR
                     QYANNISSYIYLFSMAVGMGTAIVVGRLVGAREKDTAYKRVLSSVKWALLVTVIIDAVV
                     IFFRVPLLGLFTENPEIIRLGAQVILLSILLETGRTTNIVIINSLRAAGDAKFPVFMGL
                     ISMVCMSLPLGYLLVFKLDMGLAGVWLAIAADEWTRAVIMYARWRSRLWEKHSLVEHDT
                     PDQPATPVPAH"
     misc_feature    complement(24999..25015)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.82"
                     /tool="antismash"
     misc_feature    25132..25148
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            25204..26217
                     /locus_tag="FGY93_RS09670"
                     /old_locus_tag="FGY93_09670"
     CDS             25204..26217
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312501.1"
                     /locus_tag="FGY93_RS09670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_09670"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_126666360.1"
                     /transl_table=11
                     /translation="MKKPTIEDVAQKAGVSKSTVSQFLNKRYKYMSDQTKDRIAEVIQE
                     LNYQPNGLARSLKQNRTFMVGVIVANIDYTLSIQSIRAIEEELQRFGIQVIICNADENP
                     DKESQYIEMLKARQVDGLIIFPTGKHADIYNQLIREKYPLVFLDRLVDGVNTRSLLLDN
                     EMAIKLAIQELVAHKHERIALITLPLGLNRITPRVERLSGYKKALEEHGLPFREEYMHS
                     VPREEIQQTLKELFQLTEPPTALLAGNDIVLAEVLKYVNARRIRIPAELSIIGIDDAEF
                     AHIYNPPITTITQPIADMGKQAAKTLLSSIEEGGESVPIIYRFVPDIHRGESVKTL"
ORIGIN
        1 ccaacggcag taagacgttc gtcattcaga cgattgatgt ggcatttaaa tacagcaagg
       61 ttggtttagc ctcagcgatg gcggttgttc tgctactgat cgtagttgct gttacactgc
      121 ttcagcggtt gctgattcgg ggggaggagg actaatcatg tataagctaa aaagattact
      181 ggcaaacacc atcaagtatg gtgcgctatt gctaggtgcg ttcattgctc tactgccaat
      241 tgttgtgatt ttgtttgcat ctttgaagac gaaggctgaa tatgcggcaa ccagtcctct
      301 gactcccccg gtgaactggc tgaactgggc gaactacgcc aaggcctttg tggatggaaa
      361 tatgctaacc ggatttttga acacagcctt tattttgctg atctctatca tcggggctac
      421 gttgaccggt tccatgatcg cgtatatttt gaatcgcttt aaatttaaag gtaaaagtct
      481 catgctgggt gcgttcttac tcgccacgct cattccgggg gtgacgacac aggtatcgac
      541 attccagatc attaacaagc tggaactgtt taacacacct tgggcagcca ttttactgta
      601 tttgggaacc gatattatcg cggtgtatat tttccttcag tttctggatt ccatcgcggt
      661 ggcgctggat gagtctgcca tgctggatgg ggcatcctat ctaaccatct actggcgcat
      721 tattttgccg ctgctgaagc ctgccattgt gacggtaatc atcatcaagg gtgttaatat
      781 ttacaacgat ttttacactc cgttcctgta tatgcccaaa acaagccttc aggtgatatc
      841 gacggcactg tttaagttta aagggccata cggttcgcaa tgggaagtca ttagcgcagg
      901 catcatcatt gcgattattc cgacgctggt tgcattttta tcattacaaa aatatatcta
      961 taacggattt gcacagggtt cagtgaaata gaaaaaaata aaatgaagtg tctaggtgag
     1021 aggagagtta agtatgagta aattgaatgt agatttggat gtaggtaacg tacgaattgt
     1081 aggagacagc ttgtcgaaaa tgccttggca ggataagccg gaaggcagtg aggctccagt
     1141 atggaggcat actgagaatc cggtcattgg acgaaatccg gtgcctggca ttgcccgtat
     1201 tttcaacagt gccgtagctc cgtatgaagg acggtttgta gggatattcc gtgctgaaac
     1261 gattaatgga cgcccgcatt tgcatctcgg ctggagtgac gacgggctgg cttgggacat
     1321 tgagacagag cgtctgcata tggtcgatga ggaaggaaat gaatatcagc ctaattatgc
     1381 ttacgatccg cgtctggttc gagtggaaga cacgtattat atcatctggt gtacagattt
     1441 ctatggtgca gcgctgggaa tcgcacaaac gaaggatttc aaaagctttg tgcgcttgga
     1501 aaatccgttc ttgccgttta atcgcaatgg agtgcttttg cctcgcaagc taaatggaaa
     1561 ctttatgttg ctatcccgtc cgagcgacag tggtcatact ccgtttggtg atattttcct
     1621 gagcgaaagt cctgacttgg tgtattgggg caagcatcgt catgtaatga gcaagggtgg
     1681 tcagggctgg tggcaatcgg tgaagattgg tggcggacca gcaccgattg agacgacaga
     1741 gggctggctg atgttctatc atggggtgac aggcacgtgc aatggactgg tatacagcat
     1801 gggagtagct gttcttgatc tggatgatcc gtccaaagtc aaatatcgtt cctccaactt
     1861 cgtgttgacc ccagaggaat ggtatgaaga gcgtggcttt gtgccaaatg tggtgttccc
     1921 gtgtgctaca ctgcatgatg cagacaccgg aagaattgcg atttattatg gagccgctga
     1981 tacgtatgta ggtatcgcat acacgacagt atctgacatt atgaagtatg tcatcgcaac
     2041 ggatgaagta gtcgcagatg atcgtgagtc aggccggatg taggaggaat tttacatgcc
     2101 ggaggatatg tctttacagc agctacagtc ctatatgggg agtaatccaa agccgcagga
     2161 ttttgatatg tactgggaac gggcgctaca ggagctggaa cgacagccat tggaatatac
     2221 actggagcct gccgaatttg tctctccact ggtggagtgt taccatctgt attttactgg
     2281 agtgggcgga gcgagggttc atgggaagct ggctcgtccc aagcatctta cggaacaagg
     2341 tccagccttg gctatgtttc atgggtattc ctgcgacagt ggcgactggt tcgacaaggt
     2401 gagctatgcg gcacacggat tcactgtgct ggccatggac tgccgagggc aaggcgggct
     2461 gtctgaggac aatttgcagg ttcagggaac gacggttcgc ggtcatatta ttcgcggaat
     2521 tgacgaccct gacctggatc ggttgtatta ccgcaacgta tttttggata cggtacagac
     2581 ggtgcgcatt ctaatgtcta tggagcaggt tgaccctgaa cggatcggtg catttggctg
     2641 ctcccaaggc ggggcactaa cggttgcttg cgctgcattg gagccgcgtg tccgtgtggc
     2701 ggtaccggta tatacgttcc tgtcggatta taaaagagcc tgggcgttgg atgcaacgac
     2761 atcggcctat gaggaactgg tttattattt tcgctggttt gatcccaatc atgtacggga
     2821 gagcgaagta tttcaccgtc taggctacat tgacattcaa catttagcag accgtattcg
     2881 aggacgggtg ctattcgtga cagggctatc ggatgtgatc tgtccacctt ccacacagtt
     2941 tgcggtgtac aataaaatcg tatcagacaa ggaattgctt gtgtatcacg aatacggtca
     3001 tgagtattta ccctatctgt cagatcgtgc catgagcgaa tttttgcggc tgtaggggtt
     3061 gaacttaaac agaggctcct ttatagtaat agctataacc ttcgtgaagc gtaataaatg
     3121 aatgccccat ttgtataacc tcaataatat ggtttgaggg tctctaccag gaaccgataa
     3181 atcctgatta caaaaagtgt acgtcttgta catttcttgt ggtcaggatt tttttgcgtg
     3241 atgcgaggga tttacatgac agcaaaggag ctaatgtaat gaacttcaaa gtagttattt
     3301 taaccattgc gacctttacg gtaggtctgg tggagttgat tatcggtggc gtgctgcccc
     3361 agattgcaca ggatttgaat gtctctgtaa gcacggcagg acagcttatc atgatctatg
     3421 cgctcgtgta cgctattgct gggccgactt tgttggcgtt gaccgccaaa atcgaacgaa
     3481 aacgactgta tttgtggtcg atgtttatct ttattctggg aagtctgctg gctttctgga
     3541 gtccgaacta tgctgtgttg tttatatctc gtatcattac tgctgccagt gggtcgttga
     3601 tcgtgacatt gtcactaacc attgcagtca aagtagtgtc caaagcttat caagcccgcg
     3661 ttctcggcgt tatctccatg ggggtaagtt cttccatcgt gctaggcatt ccagctgggg
     3721 tgctgattgg aaatgcgttt ggctggcggg tgctattcct gattattgcc ttgttgaccg
     3781 tagtttctat gatcattatg cacttgttta tggagcggat tccaacggag catgttgtgc
     3841 ctatgcgtga gcagttgaag tccttgaaaa atgttaaggt aatcagcgcc catctggtaa
     3901 caacgctgac actggcggga cactacacgt tgtatgctta tttcacaccg tttttggaaa
     3961 acctgatggg cttgaacgcc tcgtgggtga gtgtagccta ttttgtcttt gggctggcgg
     4021 cagtgagtgg aggttttatt ggcggttctt tggcagaccg attcggcacg gcgaaaagca
     4081 tcctcatcgt cgtgggtgtg tttattgccg tgatgttcct gctgccgttc tcgattcact
     4141 cggtgtatat gtttgcgccg cttctgatca tctgggggat tctgagttgg gccttgtcgc
     4201 ccccgatgca aagttatctt attgaaaatg cacccgaatc gagtagtatt cagcaaagct
     4261 ttaatttctc cgcactccag gtcgggatcg ctctcggttc tgccttggga ggggtagtga
     4321 ttgagaatag cgaatctgtt gccacgaatg cttgggtagg cggggcattt gtgattgttg
     4381 cttttgtctg cggcgttttt tcgattacca gagcgggcac atcgcagaca gtcagaggac
     4441 accactccgt gtcatagccc agtaggatat ttttcccttt tgttattcga aaaaacatgt
     4501 tatactactt ccaattatga agaagggggt gaggtaggtg aatcacgaga tgctgaacaa
     4561 ccgtattagc cagctgccga ttgctatggc tggcattgtt catgcttttc catacaacgg
     4621 gagaagtctg tccaatttta atcatacggt tgtaaacatc gcgagaagac gcctacctta
     4681 actcgaacgg attgctgtac cttccgaaga gtcgcggggt tgctcctgcg gctctttttg
     4741 tgttacctgg gtaagggtct tcctatataa aggagagcct gaacatgtat attgtaaacg
     4801 gtcaacaatt gaaaaaatac cacgctgcca atctgattct agatggagca acgtttgata
     4861 tccataaggg agaaaaggtg gggcttatcg gtcgcaacgg aagcggcaaa accaccctat
     4921 tacgcctaat tgcacgtttg tcccacccgg atgaaggaca gctcgttatc gccaaagata
     4981 cgagaatcgg ctacttgccg caaatcccgg cagagtttga aagcttcacc gtatacgaaa
     5041 cgctggctta cgcctatcgt gaactgaagg attgccgcaa tcagatggcc acactggaac
     5101 gggaaatgtc agatccggtt gtggcagcga atcccgagct gttagagaag ctgttgcaaa
     5161 cgtatgcttc tctacaggag cggtttgagc gtaacggcgg ctatgaaatg gatgccagta
     5221 tggatcagat agcggatggg ctaggtattc ccaaagctat gtatacgcgt aacttcgggt
     5281 cactttcagg cggagaaaaa accaaaatag cgctggcatc acagctcatt ggacgaccag
     5341 atctgctgtt gctggatgag ccgaccaacc atttggattt gaaaggattg gaatggctgg
     5401 agcaattttt gcagggctac gcaggtgcgt gtgtggttgt atcccatgat cgctattttc
     5461 tggatcgagt tgccggcaag atgatcgaac tggaggatgg cgaggccttt acgtactata
     5521 cgaattacag cggctacgtt aaggagaagg aagaacgtct gctgctgcaa tttgaggatt
     5581 ataaggagca gcaaaagcgg atcaaaaaga tgagagagac cattcgccgt ttggaagagt
     5641 ggggacgcaa tggcgataat gaaaagtttt tcaaaaaggc agcctcaatc cgcaaggcgc
     5701 tggaacgaat ggagctggtg aagcgacctg tactggaccc tcaaggtgcg gagtttcacc
     5761 taaagttgga ggatcgttcc ggtcgcaggg tgcttcaatt cgaggacatc accaaagcct
     5821 atggagaacg tcaaatatta aacgaggcaa caggcagcct ggaatttggt gaaaaggtag
     5881 ctttgctagg caataacggc gcgggcaaaa cgacgctgct caagctgttg cttggtcagg
     5941 aaagcgtaga tgcaggcacg gtccaatggg gcgcgcgcgt cgagtacgga tatttggcgc
     6001 agcaagagag agaacgggat agccgggcga cggtgcttgc ttacttcaag gaggaagcag
     6061 ggctggaaga aggcgaagca cgcgggcagc tggcgaagta tttattttat ggtgcggatg
     6121 tgtttaaacc tgtgagtatg ctgtccggtg gggagtggtc tcgcctgcgg ctggcgttgc
     6181 tggttatgaa aaagccgaat ttactggtgc tggatgagcc gaccaaccat ctggacatcg
     6241 attcccgcga ggccttggag gaagcgctgg gcacctacac gggaacggtg ctagccattt
     6301 cccatgaccg ctactttgtg aataagctgg ctggacgcgt gtgggagctg gaaaacggaa
     6361 agctgtcctt ttatctgggt ggctttgatg aataccgcgc gaagaagcgg gagctggaaa
     6421 acgcccactc gcaacgtgga gcggatgcag gagtacgctc ggcatctgca ggtagagccg
     6481 catctggtgg cggctcgggc gcgggcctag ctacgcccgc cagtgcagcg agcaatgatg
     6541 cgggaacggc tgcgcggaca ggggcgacca ccggagccga tgcgagccgt gctcgctccg
     6601 gggcggcagg tcaattgggg gcgcccgatg cccggagtgg ggcacgcgga gcgaaggtcg
     6661 cgaagccatc ccgctcaccc gctgtgtccc gcgagcggtt ggagcgggcg attgccgcca
     6721 aggaagcaga attggcggcg acagatgccg agctggaact gctcggcaca agcagcgaca
     6781 cagcgcgcat ggcggagctg tgggacgtgc gtgagcgact gcaagcggag ctggacacgt
     6841 tgctcggcga gtgggttgaa ctggagtagg cgacaggctg gttgttgaag taggcaacgt
     6901 atatttgcat aaagaatagc cctgaggtag cgcgtctgcc gaggggctat ttttgtatgg
     6961 taaagagaat gagagagtgg gaaaagaata accatatatt taaattaatg aattataatg
     7021 tttttttatt atgtatgttt acatataaag taatagattt acattttgca acatgtgata
     7081 ttatttcact tgtaagggcg aggctaatcg ctgttaaatg aattttatat tgtcatctag
     7141 aattatacat agggttttcc acatgttcat atatgacaat atttcgtatg gatgacgatc
     7201 tgggcgggat gttgttcata taaatccttc ttttctacta aagagggaag acatttcggc
     7261 gggatagata tgagtctcgt tgaaagctga gggtatatct aaatgaaagg gggggaatgc
     7321 aatggctgaa aacttatttg atctggacat tcaagtaaac aaatctcaag gttctgtaga
     7381 gcctcaggtt ctgagcattg tggcatgttc tagcggatgt ggtagcggta aaacagctgc
     7441 cagttgtgtt gaaacttgtg gcaaccggtg ctttactaac gttggttcac tctgctaatc
     7501 tcgattgttg ctttttttag ataatggatt ttattgtact ccataaaaga aaaacaagaa
     7561 ggagggacct taaagtccct tcttcttgtt tgataaatat ttatttttta actatataat
     7621 atttagagat atttttgata tcgtgtttgg tgatggaggg aaaaggtatg accgatttct
     7681 tattggaagt aaagcaggta agcaaaactg taggtaaacg aagtttgtta aataacattt
     7741 catttgagct cgaaaaaggg aaaatatatg gattcattgg cccgaatgga gctggaaaaa
     7801 cgacgatgat gcgaatcatg acgggactga tgcagcctac tagtggttct gtaaagatag
     7861 cttcatataa tatacagaca gatcgggaaa aagcgttatc caaagtaggc gctatcattg
     7921 agtctccggt cttttttgat tatatgacag gcagacaggt gctgcgtaat ttgtcccgat
     7981 tgcacttagg tgttgcatct tcggatcgag aaaaacatat taaagaattg ttggaacggg
     8041 ttggtctgga aaatcgcggg gatgataagg tcaaaaccta ctcgctaggg atgaagcaac
     8101 ggcttggtat agcccaatct atgttgggta accccgagct attgttgctt gatgagcctt
     8161 ccaatggtct cgatcccatg gggatgcgtg agttgaggga tataattctt cgtttgcgtg
     8221 attcagataa ttatgctttt tttgtctcca gccatctgtt ggatgaatta cagcaaatgt
     8281 gtgatgagtt gattgtcatt aaggaaggaa cgcttatttg gaagggggcc gctgatcaac
     8341 ttatcaaaga tggccaacgg ttagaggatg cctttatggg gctgatgggg ctatgaaaac
     8401 acttgtttat agtgaatttg agagattatg gagaaggaaa tggttttggt tattggtttt
     8461 atgcacccct gtacttgtat attcgacggg gatatacata cagcatacgt taaggattcc
     8521 tgtgaaggac ttatccaaaa tttttattgt tgcaggcttg cgtgaaaatc tatatttaat
     8581 atgtaatttt gctgtggcta ccctggtggc tgctgttttt acggaggagt ttaggagcgg
     8641 acagctgagg ttgttatttg tgcgtcgttt tacccgtggt cagatctttt ggagtaaatt
     8701 attggtagtt aatacttcta ttttacttct tctgattgta tacgccgtat cctcgcaagt
     8761 aattgttgtt ttttggaagt tctcgcataa tataaacggt acagatattt tcgggcaaat
     8821 atggtcccaa gtgtttgaat attatgggtg ggcatttgct tctttattag ctatcagttc
     8881 actctattct tttattgcta tgtgcagtaa aagtgtaaca tatgcaattg gtatttgtat
     8941 gacctataat ctgggtgttt tgttatttga tccgttgtac atgaaattgg ctactttatt
     9001 ctcttctatt ccactcttaa agaatctgat tccattttta ttaattccat atttacaata
     9061 caagggacta gatcaatcac tgatatggaa ttggtccgtc aatggggcaa ttgtgattgc
     9121 cgtcttgttc catctgattc tttttacagg gtgggcatac cgccgcttta caacggatga
     9181 ttatttgtat taggaggatc tatttatgtc tggaatttgg ttgagcgaat tagagagaat
     9241 ttggaatcgg aaatctactt ttttattata tatagcaatg ctccttatca tttttgtgaa
     9301 tatatggagt cttaaaacaa atggtacaat gcgatttcga tttggtgagg gaactgtagt
     9361 tgttaataat ttaaatctgc catggcttat gatgagcgaa atttctcttt ttttaatctt
     9421 agccatgttg cctatactgt atgtcgatca attaggcggc gatcttcata gcggagcata
     9481 tcggctatat gtattgcgac catatcgtcg ttttcaattc tggcttggca agctgctcgc
     9541 tttatctgtt acaaccgcca tatttacagg tacggctttg gtgataggca tagtggctgg
     9601 atggttactg tttccccata cctctacctt ttttaaatat ggttcaggag taatatctcc
     9661 ctcatcggat gcaatcccat atacgcttgc attctatttg attttaacac tggcctgcgt
     9721 ggcaaagttg ctgttagtta gtgctgtctg cttgtttatt tcaagacctt tgtttgcttt
     9781 tatcgcaatt tttgttttat ctgtcgctct ttatcaggtg gttagaccgc ttgtcttact
     9841 tatggatccc tttcaacaaa ttatgcttgc tttaagggtg gaaggttcct ttaagttttg
     9901 gatgtgctta atcgcaatta ttttggtcgg ctcagttatc agctttgtac gttggcaaaa
     9961 gaaaataatt taaaagtttg ttttagaacg gaggttcctt atgaagacaa caggaaatct
    10021 gtacaaaacg ttagattttt tcatgcttcg tactcctgta ttacccattc aagagttttc
    10081 taaatgcttt ccgagcagta ttaaagaggg gggggacgct agagagattg cattagagcg
    10141 tttattggaa ttgtcccgtg atccgttcat tcgtgaagct ctagccgcct ccagtcccac
    10201 tttgcttgaa tctttggtac atatcagtaa tcatgagaat ccgcgcaaac aaggacaagt
    10261 aatcaaagct tttatgcgtt atatcattag aatgattaca cggccaacgc cgtttggctt
    10321 actatctggt atcacatatg ggcgatttgg ggaacgatcg cagctatttt tgcaaggaac
    10381 agacacgttt aaaaagcgtg cgagacctga tatggaatgg ctaatgaaag cggttgagct
    10441 ggttgaaagt cgaaaggaga ttgtgcgcca actgcgggtt cggagtaata aattaattta
    10501 tcgccagggt aaccgtgcca aaattcctta tacgacaaga catggcagta tgaacgatgg
    10561 cgaagatcag agtgtgtctg ttcgtataac tcaagtattt gactgtgtaa tggctgcgag
    10621 ttcagccttc ataccatttt tggatttggt cgatcatctt aataaaactt ttgagagtgc
    10681 taatattgag gtaattgaac gttacgtgtg gcaacttttc gaacaagagt ttctgatttc
    10741 tgaacttatc ccacctacga cgactactga accgttaagt tatatacggt ctgttctgaa
    10801 accagtaaca ggtatcgaag agttaaaaga agatcttgat acaatcgcag atacttctgc
    10861 taaatataat catcttccta taggtcaagg agaacaactg ttagagagct taagacaaaa
    10921 aatgaacaaa atgtttagtg caaaatcaag tttgcaaatc gatctctccc tggaagatag
    10981 aggtatcatc cttccacaat ccattcgtaa ggatattgag tgtgttgccg aattattgac
    11041 caaactttca acgcgtgaaa acagaccttt gaatgagttt tgtgtggaat ttttggagaa
    11101 atacggacca tatcgggagg tacctttgct ggatctgctt gatgaggaca cagggctagg
    11161 ggccccggca ggctataaac accctatgag tcgtcgagta cggttacagg acatgtctcc
    11221 atccaagtcg aggtcacatc aagaaaagct tttgtttcaa tggtttgtat ctgctatgca
    11281 tgaaggaaag catgaaattg tattgacaga taacatgatc gatgaattga taaagggtca
    11341 cgatacggag aaatggctag ctgcaccctc catggaatta ttttttcagc taattacttc
    11401 tgatcaggag gctttggatc aaggtgaata tacgttgctc ttagcaccta atcaggggtc
    11461 tgatgcagca ggaaagacat tcggtaggtt tatggacctg ttcggggagc cttttaacga
    11521 tatattttct agtatccagt cggaagagca gcgtttgcaa cctggaaagc tgcttgctgg
    11581 gatatcttac ttgcctagct cgggaagatc agctaatgtc gtgttgacga aacaaactcg
    11641 accttatgag atcgcaatag gggctaatca tacaatgccg gaagatcgac aaattcatat
    11701 ttccgatcta gtcgttggtg tgcggaacga tcacttttat ttgaaatcaa aaagccgcaa
    11761 tcgagaggtt attgctagtt cgggacacat gcttaatgca gagttgacgc ctaatatata
    11821 ccgttttctc gtggaggtta gcgataatag ttaccgccat tggtcgccta tggagtgggg
    11881 atttgtggct cacgcccctt ttaccccacg tctcaggtac aagcatatca ttctctaccc
    11941 gggaacatgg agaattgcaa gtagctcatc gaagaagatg gcagacttcg ccgaagagat
    12001 acgtttattt caagagaagt ggaacatacc acgttatgtt tatatgattg aatcggataa
    12061 tcgtatttta ctagatatgg atcatccgtt gcatatcgaa caaatatgca gggaccttca
    12121 gtctaaaggt aaggttacct tgatagagca cattggcggc cttgacaatt caccagtctc
    12181 ctgtggaaaa ggacatttaa ctgctgaatt tgtatgtcct ctcgttcgaa atcaagctga
    12241 agatacgcaa cattttgtgg aagagactgc agcttctctt gaattggttg caaaagaaaa
    12301 tgagcaacaa ccaacaaagg cagactatac ttacctgccg ggagaatctt ggttctacgc
    12361 gaagctttac ggtataaata gccgacaaaa tgagtttata ggtggatatt gggaagaatt
    12421 tgtgcggaag catcaagaca acggtactat ccttcaggca tattttatcc gatatgccga
    12481 tccggacaag catctacgtg tccgatttga gctttcaaaa aataggacag cagatggatt
    12541 tctctctacg tttcataaat ggacagaaat gctgctgcat gaagggatga tagccagggt
    12601 ggtcatcgat acatatgagc ctgagataga gcgatatggt ggaagtaaac ccatggcctg
    12661 ggcggagaga atgttttcgt gcgatagtga ggtaacagct aagcttgtac acctcatccg
    12721 gtttaaccaa gtttccttag aagaagatat tatagccacc ttaagtgtta tcaatcttct
    12781 ctatcaattt ggttaccatg agaaagatgc gttcaactta ctgaatcgat attttgatgt
    12841 taaggaatat ctggagaatt tccgcaaaga acggaagttt tttttacaat ggtttgcatc
    12901 cgatcaggaa atttcacaat ccattcaatc caatctccaa gctatagaga gtattttcaa
    12961 gataagaaga gaagccgtaa agcagtatag ccatgtactc tatgagcatg aaacgggggg
    13021 attatccact aacacaagag aagatatcgt atttagtgta attcatatgc atctgaatcg
    13081 actgctaggg atagacaggg atcgagaacg gaagatcatg attatggcca gacatgctct
    13141 gaacagttta gttcaatatc gggggaatcg acaatgaccg atattcaagc gaaaatgaat
    13201 ctagagtctt ccactatctg gaggtcggtg cgacaggggg taaagttgtt ttcgttggta
    13261 tttggtatga ataagacgta catggtatca agcattttct tgcatattct tcagggctta
    13321 atgccagtcc tgacactaat aattatgcaa aaccttttaa acagcattgt ttccttcggc
    13381 actcaaggca tctccttgat tatgttacag tttggcatat ttatagtgat tcacgtactg
    13441 aaaagtgtag ttacaatgag ccaaacgttt gttgaaggta cgctggaatc agtgctgtct
    13501 aagtctctga acttaatgat cgggaaaaaa tcaagctctt tgggattagc tgattatgag
    13561 aattcagaaa taaatgacca attaaagcgg gcctctcagg aggcctctta tcgaccgtat
    13621 caactgtata cacaaatggc aggaatttta tccagtatgg ttaccatggt ctcttccgca
    13681 actttgattc ttctgtggaa atggtgggta gttatcattc tgtttgggat ctctctggta
    13741 tctgtatact ctatttttaa gctaaacaaa gaacaatttg aaatctatat gaatcgaact
    13801 ccattatatc gagagtcttg gtatatgacc tacttgttga ccaatgatcg tgcagtcaag
    13861 gaggtcaaaa tttttaatat gagttcttat ttgcttaaga gatacgagga tttgctacaa
    13921 agattttttg tagaggaccg acgaattctg gggaaaaggg tcacaatcac ttttatgtac
    13981 agtctgctgg agcttgctgt gttgttagga gtagtatggg tggctattag ggagaccttt
    14041 gagaaaaaaa tactagtagg tagcttatat ggctatattc aagcaattat gctgacgcaa
    14101 agccagatgc aggcattgat tcagggaatt gttcaattct cgcaaaataa tttgtatatg
    14161 gaacagttgt ttttattttt acagcttccc acatcagatc cggtccgaca gcaaaaggaa
    14221 caagcgctac cgattaaccg aaaaaaaaat gaagattttt gtattgagca aatatgtata
    14281 gaaggtgttt cttttactta ttcgggtaaa acagtcccct ctatacgtga tattcactta
    14341 accgtgaata gaggccaaac tatagctatt gtaggaaaga acggttcagg taaatcaacg
    14401 ctaatgaaag tactgatgca gctttactcc aattatgaag gtgtgtttaa gattaacggt
    14461 cttcccgttc aggattatga tctgcatcaa gttcaggaca aaatcggagt tgtgttccag
    14521 gactttatgc attatgaaat gtcagcacgt cataatatcg gctttgggtc gctagaacgt
    14581 ttggaaaagg atgaagagct catccaagcg gctcgatatg cagctataga tcagattata
    14641 accgagcttc cgcgaggatt agacacgcaa ctcggaaaat ggttcgagga tggcttccag
    14701 ctctcgggag gacaatggca gagaatcgca attgctcggg cttttttgcg ccaggcagat
    14761 atatatattt tagatgagcc gagttccttc ttggatccag tagcagaaag ggatttgctg
    14821 aagttatttc tagagttaat gaaggatagc atcggaatct ttataacaca tcgaatttct
    14881 tcggcacgcc tggcggataa aattgtggtc atggataatg ggggaattgt cgagcaggga
    14941 acccatcggg aactgatgct actggatgga ttatatgcag agatgtacaa cattcaagct
    15001 agttcattca atgacgagga agctttggcc gaaaccggag ggagagtata ggatgacgac
    15061 gatttcatat acatgcgata actggatacc cgtcaagggg gaaatgaaga acaagatatc
    15121 tacattattg cgggagatta ccgaacgtta tagaaacccg gatcaggtgc gtttatggat
    15181 gaaaaagata cctccaatag aagccgacgg ggtgataatg gaacgttggg cagatgaaag
    15241 cttgggtagt gggtttacgg gaatatgttt gctcatgggt cagctggatt atctttatcc
    15301 caaaaatggt tgggatattg taggacatca atatttagag cgaatccgta tggtggtaga
    15361 gcaaaaaggt gttcacgatt tatccttgta tagtggattg gcaggtatta tgctggccat
    15421 ttactcttta tctaggaagg gtacacgtta tcaaggtatg ctagatgcac ttgcttcatg
    15481 gtttgaagaa gctgctttac aaagtctggc tctacatcgg attgagtggg aaaagggaga
    15541 gctgcggatg agtcaatatg acaccatctc tggctttgcg ggagttgggc gtatagctat
    15601 gctgttcctg aaccgcccgg gcatgcagat ggtatgggaa cagacaatgg atttgttcca
    15661 cgtcatgtgc ggtgagaaaa atctaaatgg tcacactgta cccgcttggc acatttcctc
    15721 ggaacatcag tttcaggagg atgaaaagct acagtatcct caggggaatt ttaatttagg
    15781 tatttcgcat ggtattgcag gtcccttatg ttttctgagc ttgtctgccc ttcatggagt
    15841 ggacgcctcc cctttaatga acgatataca tagactggga aagtttatac atcattggcg
    15901 tgttcaggac gtagagggca taatttggcc tggtcgaatt tcctttgggg agtggctgga
    15961 tggccagctt ttatcaggaa gcactcgaaa ctatcgtgat tcttggtgct atggtgtacc
    16021 aggtatcgca cgttctatct ggctagcagg acaagctgtt cacaatgaag aatggctcga
    16081 aacggggctt tccgcttatt tagatataga gaaacgcctc catcgaaaag ggggattatc
    16141 ttctgctaca ttatgtcatg ggattggggg attgttgcat ctagtccaac gtatgtactc
    16201 agatacttcc catgagcagt tagggaggat ccgggacaga ctacttgaag atgtattaga
    16261 tatgttcgat gctaattcgt tgtttggctt ctatgatcat agcttactgg atggaaggtt
    16321 agcggaagtt gatgaggctg gttttttgaa tggaagtgct ggagttgctt tggtgttagc
    16381 ctccttaatt ggagatcaga atccggaatg ggatgctgct tttctaattc gctaagatat
    16441 agaaattttt ttgcctaacc tgacactata caaatagaaa agatccaagc gaccattcga
    16501 ggttagctgg gtcttttttt atacggacgt ttagggtaga aatacggtgt atcgtttctt
    16561 ttctgcgagg gacgggtatt aattgtctag taccgcatag attgacatag gggaaaagga
    16621 ggtatgagca tgtggaatgg ggtcaaaaga ctgtctgcac tagcgtcgat tctgctgcta
    16681 gcgatcattg taagcgcatg cagtaagggc gatgcttcag gcaaggtgca aattgagttt
    16741 ttccaaaaca agccggaggc caaggattcg ttcgataagc tgatcgctca attcaatcag
    16801 gaacatcccg gtattgaagt gacacaggtc aatccgccag aggcagaaac ggtgttattg
    16861 acccgggttg tcaaaaacga tgtacctgac attgtgggac ttggggccac ggatacctac
    16921 tccattttgg cacagagcgg tatttttacg gatctcgcga atacagaatt gccacgtacg
    16981 gtggacccga tttacctcaa aatgcttaag gatgtgactg gggtcgatcc cgtgtatgga
    17041 attccttatg ctgcgaatgc gaatggtgtg atgtataaca agacactttt taaggaaatg
    17101 ggattacagg tgcccaaaac gtgggatgaa ctgattgcaa cggcgcaaaa gatcaaggct
    17161 gctggtaaaa tcccatttta ttttacatat aaagatgatt ggcaaacgaa ccttcctttt
    17221 aatgcattgg gtccgaattt ggtgggcatt gatttttttt tgcaacggcg tgagaatcag
    17281 gtcacctttc aggacaagta ccgggaggtt gcggaaaagc agctggagct gctgaaatac
    17341 ggacatagtg ataattttgg caaaaactat gctgacggta accgtgcttt cgctaacggg
    17401 cagggactga tgtacatcca gggctcgtgg gctatatctg aaattcgcaa agctaacccg
    17461 aaagtggaac tcggattttt cccgttaccc acagggaatg acgcaaaggc ggtcaagctg
    17521 gtgtctggta tagatacgct tttagctgtt tcggaaagca cgccgcataa aaaggaggcg
    17581 gaggagttca ttgccttctt attaaaaccg gagaacagca agcaatacat tacggaacaa
    17641 acgttgtttt cagcggtgaa gggagtcacg caggatgatc cgagtgtggc agagctgctg
    17701 ccgtatttta aatcaggccg tgtcattgat tttgccgatc attatattcc caaagcggtc
    17761 caattgaatt caattgtaca ggcgttcctg caaaacggag acatcgatgc ctatctagcc
    17821 aagctcgacc gggagtggaa taaggtagct aaccgccgat aggggaggag gacgagacat
    17881 gaataagcga ctaacgactt tttactggat gacggtgccg gcggtactat tattttttat
    17941 atttttgacc ttacctgcct tgcagggatt ttattactcg ctcaccaatt ggaacggatt
    18001 cggccatcag taccactttg tcgggtttaa gaactatatt aatttgtttc aagacgacaa
    18061 tgtgggcaat gcttactggt ttactttcaa atttgcgatt gtggttacca ttgcgattaa
    18121 tattctcagc ttgctgattg ccatggggct gaacgctaaa atacgtttcc gtaatttctt
    18181 tcgcgggatt tatttcttac ctaatatttt gagcgtgttg atcgtaggtt acatattcaa
    18241 ttacctgttc tcgaatgtat ttacgatctg gggacagaac ttaggcatca gttcattatc
    18301 gacaaacatc ttaggcagtg agcagttggc ttgggtagga gtggtcatcg tagccgtatg
    18361 gcagggcatt gcctttaata cgattctcta tctggcaggg ctgcaaacga ttccgaccag
    18421 tctgtatgag gcatccaatc tggacggtgc aggtaaatgg cgtgaattct ggagcattac
    18481 ctttccgttg attgctccgt tttttacgat caatatggta ttggcgatga aaaattccct
    18541 gatggtattc gatcagatcg tggccttgac gaacggcgga ccgggacggg ccacacagtc
    18601 gatttcccat ctgatataca ccgggggttt tagaggtggg gaatttgcat atcagtcggc
    18661 taactctgtg atttacttta ttgtgatcgc gatcatttcc atcttacagc tgcgattcct
    18721 ccagagaagg gagatggaca actgatgaaa acaagcagac gtaccaactg gcctgtgctg
    18781 attctggtag cgttggggac aatatttatc ctgtttcccc tctatatgac ggtgacgatt
    18841 gcccttaaaa atcccgagca gatggcgcat tccgcctttg cctttccgac cgagctgcat
    18901 tgggaaaatt ttagtcgtgc agtggaaatg accaactttt tcagtgcttt tcagaacagt
    18961 gtgatggtca cgacatcgac ggtcatactc actttgctaa ccaattcgat ggtcgcttat
    19021 gcgattgctc gtaatatgca gcggcgtttc ttcaaggggt tatattttta ttttgtgagc
    19081 gccatgttta ttccgttccc gatcatcatg ctgccgattg tgaagctggc ctcgggcctc
    19141 catatgacca atctgttggg ccttatcgtg ctgcatacgg tatatggctt ggcgtttaat
    19201 gtcttcgtgt atgtcggtta tattcgctcc ataccggtgg cattggaaga ggcagctacg
    19261 gtagatggcg cgacgacatg ggggacattt tggcgtatta tatttccgct gatggcgccg
    19321 attagtgcta cggtagggat cctcacttgt ctgtccacat ataatgactt tttgctgccg
    19381 ctcattatta ttagcgatgc ggagcaatat acactgccgc tcgttcagta tgtatttcag
    19441 gggcagttca ataccgactt taatctggcc tttgcttcgt acctgatggc cttactgccg
    19501 atgattattg tctacctgat tgcacaaaaa tggattatca atggtgttac gcaaggttct
    19561 gtgaagtaaa gcggagctac aacagcttca cgcagactgt gccttgttag acaaataaaa
    19621 aagggggttc ctatactgtg aatcacacag gtatagagaa ccctcttttt atagcattgt
    19681 tatttagata ctttgctgtt gcttgtcagt ggctgcaagg gtacggtcgt ctctgcttcc
    19741 gggtcgtctg ttgtatagta gaacatataa atagaagctt cctttccctt gaagttcttg
    19801 tagacatcca ctgccttatt attgccatct ccggcgaagt tggccgtgat cggcttgcca
    19861 ataatccttt ctttccccag gccaatatgc gtctggttga tccctccaaa gtgagtatcc
    19921 tcactttcgg tttctacgaa taaatctgct ccttgtttgt agtaggtcca cttcacagga
    19981 tagccaccga tttgcgtcgt tagcgtctgt ttttgctcag aaatatcagc taaacgctgt
    20041 ggcgttttgt catccgaatg ggtcgtaacc ttgtatttgc ctgtaaatgt aatgggagtg
    20101 tccttggtaa tcacaagatt ggccggtctt tcaaaacgga tcgtgttcag atcgtgttcc
    20161 tgatcaggtg aagaccaacg gctaccctct aacgttgtac cgttcacaga aagaaaatat
    20221 ttttgataag gtaacatggc gaatttctcc ttgcttctga tcgtgacacg gatttgtgtc
    20281 ggtgtgacaa tcatttgttc cagcataaaa ttcggattgc cgttctctaa tggggtattc
    20341 agcacgcttt ttattgtacc gctctccatt ttcttcttgc ttaactgcag gtcaaatttt
    20401 aggggctcat gtatactttt ctcggtttgt gcatattgca gtttaaaagt agtttgccct
    20461 tctggtatat cctctttagt aaaatactgc tgggctgtgt attctccgtt ctcaccgggt
    20521 gtaccaaatg tccctccaga ttgaggattc acaggcttcc catctttgta ggcaataatt
    20581 tgtggattgt cccattcctt tggtatggac gaatcgaagg taattgctga ggacagcatc
    20641 agcttgtcct taccttgttc aaatacttgt accttcatat cttgtaagcc gttacgatcc
    20701 agtttgaaag tctgcgtctg aggtgatttg atatcgagcg gcaaatccaa ttcctgaacg
    20761 ctggtgagct caacatgatc tacagtcagc cgcacgttct ctgtttcttg ctgcggtgtc
    20821 caatcacttt caaagtaacc gttatagcgt tgatttttct cgtcccattg ctggaagctg
    20881 tactcccctt cgctgctttt ccccgcagca tttttaagtg atacgccttt gacattccaa
    20941 aactcgttgt ctgtacgttt tccgacttcc aggctgtaca gaatcacagt ccgattctca
    21001 tcgacaatag cggtatgcaa cgtcagcttt atcccgtctc tggtgacaga ctgttctaaa
    21061 ggctgtccaa ggttttgagc taaagccgtc tcaattccac ttcttccgtg cagcagattg
    21121 tcccagttat aatggatggc ggcatagacg ggaacggcaa cgagaagtgc gctcagggaa
    21181 gcagcgatgg ctattttgcg ccaattacta tgtcggtgtg gagtgaatga atcggaagca
    21241 tcggttagcg taggggcagt atatcctgcc tgttccatcc ggttccacat ttcattgaag
    21301 tcaggatagg ctatttccga atcttcattt aacttgcgct tcaatgcctt ttctacgttg
    21361 ttcatagttc tctccttcca tctcgggaaa ctgtgtgcca gcctcccgca gtatttgctc
    21421 cattaacttt agccctttgt gtgttctgga tttgacggtt cccagcggaa tttccagcag
    21481 cttggatatt tccaccagcg tgaaatcgtg catatagcga agtgtcagca cagcgcggat
    21541 tttggccgga aggcgattca tataaacggc ccattcctca gccgactcgc gttcctccac
    21601 ctgcctgtct actgacttgc tttcggttcc ggtaaaaaga tggagattgg ccgatacttt
    21661 cagatgcagg ctttttcggc gtttaagatg gttcagacaa tgattgaccg taactttcat
    21721 aatccaggct tttagttgct tgatgtgctc acgattgctg cgaaacaagg ttataaacac
    21781 ttcttgtgtt aaatcctctg catctgaggc gttatggacc atgtagtagc aggttcgata
    21841 tacatcccgt tgatacagat caaacaactc tcgattactt tgcaatgatg gctctccttt
    21901 ctcgtgcagt ttatctatac aacaactgga gttcacaaaa ggttcatttg gttgtgaaaa
    21961 ataaattgtc cgcttcgatg tgcccacttt ttctccaatg taccacacaa aaaaagaagc
    22021 ctgtaaatct caaaactgca gatttacagg cttcttatat gtttcattgc tacgacccta
    22081 cgggatgaac acaccttcgc gcaaaaaccc gtcaacggat agcttgtgga caaccttccg
    22141 cttaatcagc cagccgtaca atcgttctac cctgtgagcg ggctgctagg atgtcttcga
    22201 gcgcgcttgg caggtcagcc aagccaattt cgcgctcaac gagctgttct agctgttccg
    22261 gcttccaatc actgccgagg tgcttccaga tcgctacgcg ggtgtcatag gggcagaaga
    22321 cagagtctat gcccagcaga tttacgccgc gcaaaataaa tggcagcacc gtcgtaggca
    22381 gcttggtgcc tgccgtcagg ccgctcacgg caacagagcc gttgtaggcg atctggctga
    22441 gcagcgaagc gagcggcttt ccgcctacag ggtctacagc cgcttgccaa agctgcttgg
    22501 ctagcggtcg gatgctctcg gcaccgtcgt aaacctcctc acgcgaaata acatcggctg
    22561 ctccgagcgc cttgaggtaa tcatgggatt cgactttgcc actgctggct acgacatggt
    22621 agcccctctt gtgcagcaag gcaatggctg caccgcctac cccacccgtc gctccggtga
    22681 cgagcacctt acccttctcc ggcgcaacgt cgttttgctc cagccgatat aacgacaggg
    22741 ctgcggtgaa tccggctgtc ccaaaaatca tcgcctctct cagcgtgagt ccgtcgggaa
    22801 gcggaaccac ccagtccgca ggcacgcgcg catattggct gaatcctccg aattgagaca
    22861 cacccagccc gtacccggta acgagtaccg cttgtccttc gctaaaacgg ctatcctccg
    22921 aagagacgac ggttcccgag caatctatgc cgggtacgaa cggataggat ttgacaatat
    22981 tgccatcctt gcgggcggca agcccgtctt tataattgat gctggaataa gcgacacgaa
    23041 tcaatacttc tccagcaggt aaattgtcag ttttcaaaga acgtacttct gcttgaacct
    23101 ctccgtcatg cgtctgatcg acgacaaggg cttgaaatga ttgagtcatc tgtaaaagcc
    23161 tcctttatta ccgtttaagt ctatgaatga cctatataat ccatttctaa cttacaaatt
    23221 atgcttagga agcatacaac aatctgcaca tcctgtcagc ggcaatgctc acaagctctt
    23281 aatctattat accctttagc tcataacgac gtcgaaaagt ccagattatg gatgtatcct
    23341 tgcaacatcc tgtttcaata aagttcgata atcaattata agaaggtgat aaatgaattc
    23401 ttacgtattt ttcaaatcat tttacgtaaa cgggatgtat tttcagaatg actgtgctaa
    23461 catacccttt gatcattaaa tattctatga agaaaggtga atgaatgaca accagagcac
    23521 taaaaaatgg ttcggtattg tccgaagcca aggaactgaa tttgttccgt ttgacatggc
    23581 ctattttcct tgaattgttc ctgtttatgc taatgggaag cgtcgataca ttcatgctca
    23641 gttctgtatc tgataatgca gtgtcgggtg tgggcgcgtc caatcaaatt atttcaatcg
    23701 ctatccttgt actggaggtt atcggcaacg gcgctgctat cgtcgtagct caatatatcg
    23761 gttctaagaa acttgtcgaa gcggcccagg tgacgggtac ggccattact ctgaatttaa
    23821 tggtaggtct tttgctaagc gtgatttttc ttgtgtttgg tactcatatg ttgcaatggc
    23881 tgaatgtcca gggggatatt ctgacttacg cagaatccta tatgagtatt gtcggggggg
    23941 ccattttcct tcaggcattg attaactcgc tggcggcgac cattcgtacg cacggtttta
    24001 ccaaagaaac gatgtatgta tcggttttta tgaacgtgat ccacgtggtc ggcaactatg
    24061 ttttgatttt ggggcattgg ggaatgcctg cactcggtgt agaaggtgct gctatttcta
    24121 cagtaggtag ccgctttatt tgtctcttga tcttcttctg gctgatgtac cgggtaactg
    24181 aggtccgtgt cgagtggaaa tattacgtcc atttatccag aaaatttatc acaaaaatat
    24241 tgcgtattgg tgtaccatcc gcgctggagt ccatcatgta tcagtcgtgt cagctcatat
    24301 ttacactgta tgtgacttat ctgggcgctg aagcgatggc gacacgtcaa tatgccaata
    24361 atatttcgag ctatatttat ttgttcagta tggcagttgg tatgggaacg gctattgtag
    24421 tggggaggct cgtgggagcc agggagaagg atacggctta taaacgtgta ttgagcagtg
    24481 tgaaatgggc gctgctcgtg actgtgatca ttgatgcagt ggttatcttt ttccgtgtac
    24541 ccttactcgg tttgtttacg gaaaaccctg aaattattcg tttgggtgcg caggttattt
    24601 tacttagcat tctgctagaa actggacgga cgacgaatat cgtcatcatt aactcattgc
    24661 gtgctgctgg agatgccaag ttcccggtct ttatggggtt gatctccatg gtctgcatga
    24721 gcttgccgct gggctatctg ctggtgttca agctggatat gggactcgct ggtgtgtggc
    24781 tggcgattgc tgctgatgaa tggactcgtg ctgtcatcat gtatgcccgc tggagaagcc
    24841 ggttatggga aaagcattcg ctggtcgagc atgatacacc ggatcaacct gcaacgcctg
    24901 ttccggcaca ctaatccaag tagttattcg ggttaactgg aacctagctt tttgatagag
    24961 ttgtatacgt ggaggtagtt caagagaaca tcttgaacta cctctttttc ctgcatagag
    25021 tggaaatagc agtgagccaa aagttgtata tgaaaatgga gttggcgaag tggcaccaca
    25081 ggtaagtttt aagctcaaaa tatatcataa tggcattcat aaatagaagt atggtaaatt
    25141 tactaaaaga aagatatact tttgttgcac taacgcagta catgaaagac aaggagtgta
    25201 ccgatgaaga agccaacgat tgaagatgtt gcccagaagg cgggagtgtc taaaagcacg
    25261 gtctcgcaat ttctgaacaa acgatataaa tatatgagcg accaaaccaa ggaccggatc
    25321 gccgaggtta ttcaagagct gaactatcag cctaacgggc tggcccgcag cttgaagcaa
    25381 aaccggacgt ttatggtggg agttattgtg gccaacattg attatacgct gtcgattcag
    25441 tctatccgtg cgattgagga ggaattgcag cgctttggca ttcaggtgat catttgcaac
    25501 gccgatgaaa accctgacaa ggaaagtcag tatattgaga tgctcaaggc ccgccaagtg
    25561 gacggcttaa tcatcttccc gacaggaaag catgcggaca tttacaacca gctcattcgg
    25621 gaaaaatatc cattggtgtt tttggaccgc ctggtggacg gtgtcaatac acgcagcctg
    25681 ctgctggata acgaaatggc gattaagctg gcgattcagg aacttgtggc tcacaagcat
    25741 gaacgaattg cgttgattac cttgcccctt ggcttgaatc ggattactcc acgagtggag
    25801 cggctcagcg gatataagaa ggcgctggag gagcatggct tgccatttcg tgaagagtat
    25861 atgcacagtg tgccgagaga agaaatccag cagacactga aggaactgtt ccaactgacg
    25921 gagccgccga ctgcactgtt ggccgggaat gatattgtgt tggctgaggt gttgaagtat
    25981 gtgaatgccc gccgtatacg tattccggca gaattgtcca ttatcggaat tgacgatgcg
    26041 gagtttgccc atatttacaa tccgcccatt acgaccatta cacaaccgat tgcggatatg
    26101 gggaagcagg cggcaaaaac gctgctgtcc agcattgagg aaggcggcga gtcggttccg
    26161 attatttacc gatttgtgcc ggatatccat cgaggagaat ccgtcaaaac gctgtaaacg
    26221 agtatatgtc atatatataa aaatagcccg tattcctttg tacgacctga gtatgcgtat
    26281 gctgctcagg tcgtacaaat gcgaatacgg gctattggaa gttaaggctg acttaggatt
    26341 cggccttgtt gagcttgcgc tcatagcggt gaaggttatg cggggaatga acccaaacta
    26401 attggtgctg gcgctgagca aaaaagattc caatt
//
