LOCUS       NZ_CP040829            27010 bp    DNA     circular CON 23-AUG-2024
DEFINITION  Paenibacillus polymyxa strain ZF129 chromosome, complete genome.
ACCESSION   NZ_CP040829
VERSION     NZ_CP040829.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5703931)
  AUTHORS   Li,L., Li,B., Xie,X., Chai,A., Shi,Y. and Xu,S.
  TITLE     Complete genome sequence of biocontrol strain Paenibacillus polymyxa
            ZF129 and further analysis of its biocontrol mechanism
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5703931)
  AUTHORS   Li,L., Li,B., Xie,X., Chai,A., Shi,Y. and Xu,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JUN-2019) Institute of Vegetables and Flowers, Chinese
            Academy of Agricultural Sciences, No.12 Zhongguancun South St.,
            Haidian District, Beijing 100081, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1092.65x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_006274405.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:29:48
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,145
            CDSs (total)                      :: 4,988
            Genes (coding)                    :: 4,933
            CDSs (with protein)               :: 4,933
            Genes (RNA)                       :: 157
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 55
            CDSs (without protein)            :: 55
            Pseudo Genes (ambiguous residues) :: 0 of 55
            Pseudo Genes (frameshifted)       :: 33 of 55
            Pseudo Genes (incomplete)         :: 26 of 55
            Pseudo Genes (internal stop)      :: 10 of 55
            Pseudo Genes (multiple problems)  :: 13 of 55
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 15:14:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 86842
            Orig. end                         :: 113852
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP040829.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27010
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..27010
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27010
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17010]"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17010
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(74..1663)
                     /locus_tag="FGY93_RS00440"
                     /old_locus_tag="FGY93_00440"
     CDS             complement(74..1663)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370180.1"
                     /locus_tag="FGY93_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00440"
                     /product="amidohydrolase"
                     /protein_id="WP_019686793.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.3e-11, bitscore:
                     41.7, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFVLFKHGRLYGDWASKGDSIVVQHGRIQAIGYARELELQLSGK
                     EYETVDWEGANVLPGLTDAHMHLSMHGMKLAMLDFTSATSKDEMLAMLRKRVAVTPPGE
                     WILGLNWNENAFIPVEIPNIAELDAITDQHPVYLTRTCFHTFLANSEAFRRAGIHENTP
                     DPASGAYGRDAEGRLNGLIYEEASFAFTSVQPEPDYSAKKDTIRRACLDALRLGLTAAH
                     TEDLRFLGSVETMQRIYKELREEGLAFRTHQLIYHPFMEEVKVQKLCAGTGNEWFKIGA
                     IKMFADGAIGGRTALLSEPYSDAPHTCGMAIQPQPELNQMVAAARAAGFPVAVHAIGDG
                     AAHMILTAMEAHGLTEESGLPDRLIHGQVLRADLVKRMVKLPLIADIQPRFVASDFPWV
                     LDRVGKERTEYLYAWKKLLQAGIPCAGGSDAPIEPLNPFLGIHAAVTRAKPEEMHEGYL
                     PAEKLDVHEAIHLFTMGSAVAAGEADERGTIAEGKAADFTVIDRDVSESHQALLDVKVR
                     MTVVNGQVAYRS"
     gene            complement(1711..2409)
                     /locus_tag="FGY93_RS00445"
                     /old_locus_tag="FGY93_00445"
     CDS             complement(1711..2409)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (103-161). E-value: 2.4e-12. Score:
                     38.8. Matches aSDomain:
                     nrpspksdomains_FGY93_RS00445_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426685.1"
                     /locus_tag="FGY93_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00445"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_019686792.1"
                     /transl_table=11
                     /translation="MEIYAIDTSKPEAEEHYELLVNQVSLEKQHKLDRFLHREDALRGL
                     YADVLLRWLVCRQLKIPNASLQFTYNAFGKPSLLNAPAFHFNVSHSGKWVVCAIDDHPL
                     GIDIEQLRPIDFEVGRVCFSDTEYDALMQQDAESRLSYFYDLWTLKESFVKAEGQGLTL
                     PLKSFSFELEARPSIGFTTEGFTTEYCHFKQYELDPDYKMAVCAAHDHFAQEVQQVDIN
                     TLRLEVATLA"
     aSDomain        complement(1927..2100)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FGY93_RS00445_ACPS.1"
                     /evalue="2.40E-12"
                     /label="FGY93_RS00445_ACPS.1"
                     /locus_tag="FGY93_RS00445"
                     /protein_end="161"
                     /protein_start="103"
                     /score="38.8"
                     /tool="antismash"
                     /translation="LGIDIEQLRPIDFEVGRVCFSDTEYDALMQQDAESRLSYFYDLWT
                     LKESFVKAEGQGL"
     gene            2636..4102
                     /locus_tag="FGY93_RS26690"
                     /old_locus_tag="FGY93_00450"
                     /pseudo=""
     CDS             2636..4102
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686791.1"
                     /locus_tag="FGY93_RS26690"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00450"
                     /product="RICIN domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKYDFARLLCIMLTILLSLSIFQMFSPKIASAASANVVNGIQFKD
                     TDGNVVHAHGGGMIKVDGYYYWFGENRNPNGTFKAVSAYRSSDLKNWEFRKNVLTSSSA
                     AELNVSNIERPKVIYNEKTRKYVLWMHKENGINYNEARVAVASSDTVDGDYTYQGSFRP
                     LDYDSRDMTVYNDNGTAYLISATRVNADLNVYRLTPDFLQVESLVTTLWPGQYREAPAM
                     FKKGDVYFLITSGATGWNPN"
     gene            complement(4211..4726)
                     /locus_tag="FGY93_RS00455"
                     /old_locus_tag="FGY93_00455"
     CDS             complement(4211..4726)
                     /EC_number="3.1.2.20"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /function="acyl-CoA hydrolase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014599583.1"
                     /locus_tag="FGY93_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00455"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_014599583.1"
                     /transl_table=11
                     /translation="MESKYIRETYCFKTSRVFPNDINNHNTLFGGRLMSYIDDIASIAA
                     AKLCRTNTVTASTDSVDFLLPIHPSDSVTLEAFVTWTGRSSMEVFVKVIREGLMTGDRK
                     IAATAFLTFVALDENNRKVTVPQVIPETEEQIQLHQTAPSRAAIRRQRREESKQLASFL
                     TTDFPWEV"
     gene            complement(4826..5374)
                     /locus_tag="FGY93_RS00460"
                     /old_locus_tag="FGY93_00460"
     CDS             complement(4826..5374)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429618.1"
                     /locus_tag="FGY93_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00460"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_017426682.1"
                     /transl_table=11
                     /translation="MDSMQYIIGSNLAQIRKTRGLSLDKVAELTGVSKGMLAQIEKGKS
                     NPTVTTLWKIANGLHVSFSTFLKEDPPQITKIRRADLHPVIDEDGNYFVYPVFPYHSEK
                     KFEVFTVSLKPGFTHKAEEHLGEETILMIRGEMYFEMQGQQLQLSAGDAVQFQGSDIHT
                     YRNDSDEDADFYVLIYYAD"
     misc_feature    5521..5530
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 17.33"
                     /tool="antismash"
     gene            5608..6846
                     /locus_tag="FGY93_RS00465"
                     /old_locus_tag="FGY93_00465"
     CDS             5608..6846
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426681.1"
                     /locus_tag="FGY93_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00465"
                     /product="sugar MFS transporter"
                     /protein_id="WP_126666746.1"
                     /transl_table=11
                     /translation="MNPQTRKSRHMYMMQLATIFIGFIVFGISENIKGPAIPRIQFDFN
                     LDEQQLGTLLSLNALGYLIACSFTAVLVRKWGIKAVSIISFASMIISGVFIYLSHTYPF
                     FASSYFLMYIGNGMLEIALAILGARIFVKNTGTMMNLSHFFYGLSSTVAPLLATGVMSL
                     TVFGHTLDWRGMYLAMLSLCLLPIVAALLSAFPGDDLQHEERTSLKTLTRDPALWMMVM
                     ILSFGVVSELAVGGWLVNFLEKAYSWSTVKASSMLSAFFLTFSLGRLLLGPLTDRMGFV
                     LSTILFSAFSAICTFAAIAGGERLAFLFAASGAGIAMIYPTVMAFIARRYPKDSDTAIT
                     FVVTLMGIGSVIGNYVIGWVIEGVKIVYGATTELGILRGLQAGYGVIGLCAAICAVSGM
                     ILYGYLKKRQELI"
     misc_feature    complement(6913..6928)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.02"
                     /tool="antismash"
     misc_feature    complement(6990..7003)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.91"
                     /tool="antismash"
     gene            7023..7748
                     /locus_tag="FGY93_RS00470"
                     /old_locus_tag="FGY93_00470"
     CDS             7023..7748
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820470.1"
                     /locus_tag="FGY93_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00470"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_016820470.1"
                     /transl_table=11
                     /translation="MSIASELSGTKPDSLSVLQGVKDCIPTLLGYVCIGFAAGIVGASS
                     GVSTMEIGLMSALVYAGASQFIMCSMLAAASPPSVIILTTFIVNARHLLLSASLAPYFS
                     KYSLWKNIGIGILLTDESFGVASDKLAKGGQVSDRWMNGLNITAYLAWIASCVAGGVLG
                     NWISQPEAFGLDFALPAMFLALLISQLQSVQTSKLKHRLLLVLCMAVLMYLLSWWVPSH
                     IAVIVATMITATIGVLTDK"
     gene            7745..8074
                     /locus_tag="FGY93_RS00475"
                     /old_locus_tag="FGY93_00475"
     CDS             7745..8074
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820471.1"
                     /locus_tag="FGY93_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00475"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_017426680.1"
                     /transl_table=11
                     /translation="MSISPNVLYIIIGGMIVTAIPRIIPFVVLQKLTLPKPVLQWLSYI
                     PICIFTALVMENLLVRTETSVTLNGQVLIAVLPTLVTALWSKNLLATVVVGIVSMAVVR
                     VLWLG"
     gene            complement(8113..9846)
                     /locus_tag="FGY93_RS00480"
                     /old_locus_tag="FGY93_00480"
     CDS             complement(8113..9846)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309469.1"
                     /locus_tag="FGY93_RS00480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00480"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_231124963.1"
                     /transl_table=11
                     /translation="MILLATRELINSVVAGASGGSFQPVFIAFGVLIGVNLLYDLINIG
                     ESFFRKMFQSRLSNQVNIRIIEKAQKMSLQSFEDADVQNMLQRAQGEADYRPFEIFTQI
                     LAIMSSVVTLFSTGAILIAWRWWAFLFIFLIPCLSFYSFLRIGQREFNVHFQRAGRQRE
                     SWYLSFLVTRDNSFKEVKIFQLGDYLRKRYKTILEGFYREDKVLAVRRSYTSLAFQIVN
                     QGACAFIIFMAIQATYVGQILVGNLVSLIQGITLTQSTSQSIVQGILSLCQNNLYIKQL
                     FDFLDMPEETKMQKSVQHLPLSAIHSIEFRNVSFRYPNTEENAISNVSFTLHQGEKLAI
                     VGRNGSGKSTIVKLLTHLYSDFEGEILINGHSIHELDKDSFRGKIGVVFQDFVHYEMSV
                     RDNIGFGHVAARENDEAIWTAIDKAGIVDLIAGLPEKLNTLLGKWFEDGQQLSGGQWQR
                     IAIARAFMRNADIYVLDEPSSFLDPHAEKEVFQKFDQLVHERIGVFISHRLSSARMADT
                     IILMKEGRIVEAGSHKHLMDMDGVYAEMFRLQASSYLSQGESELEQEMLSPPLVKATGG
                     S"
     misc_feature    complement(9873..9886)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.91"
                     /tool="antismash"
     gene            complement(10001..13255)
                     /locus_tag="FGY93_RS00485"
                     /old_locus_tag="FGY93_00485"
     CDS             complement(10001..13255)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820473.1"
                     /locus_tag="FGY93_RS00485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00485"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_017426678.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.9e-196,
                     bitscore: 650.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.4e-17,
                     bitscore: 60.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.8e-56, bitscore:
                     189.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRQLHYTDAHNLHREPRDKNERWFSACDYFLIRAPLLPLEQYFE
                     VFSDQDVDSHLSLEEITRRLKLVSREAVIREAISLASPSLMQFLHYLNDDDALEDKGEL
                     QKYEKTLNSFYRYFIRMTTRTTPFGLFSGVGQGICKDTTHLDIGTYHQHLKRARPDMEW
                     IYKIIRKMESDPVIFDQLKVFLNRTVMIKGDRAKLPFRPKHGAAETDDSAEMFSSIRLT
                     DVVRLTFEAAEHPIQVMELKELLLKAFPDATTEIIAHFLQQLVEQEFILSELRPPLMDH
                     SPFHYIFEKIKKMDMSDYWTDILHEIDILLRQYNQCMIGEGEKAYRELCGKMLDIIAVK
                     TPVQVDVKLAQEVTLPRHVLDDVALGAEVMCRLFSSPKMDELDEYLNRFLEKYGVYQEV
                     PINELFDEDWGLGIPKTYRTNEKKSMGMEAFKRNAVLFQWLSNAIANHDIEIVLSDEQL
                     EQLTISDNDDTSPESMEVYYSIFAESPEKVDSGDYKLLLGPSAGSNRAGKTFGRFLDMF
                     SEEYVQKFSDIYDHHRCFHPDALLAEMVFMPDQGKISNISLSKNFMEYEIVSGTTSSKD
                     EEQTLHMDDLLIGATHDRFYVKSRRLGKEIIPLQTHMLNYKLSPHVFRFLTDITNKELG
                     TWSYFDWGPLEQSPFLPRLVYGKIVISAAQWRLGKAALNISDLTEPQAREELFHTWREQ
                     WNVPRYVYLTMGDNRLLLDLCNLFHIKELLREMSKMREGQELLLTECLGDPFHTPLHGT
                     AGRYMGEFVFPLKKKKIKGKPSIPSLPHKMDSQKFMAYTPSGIHRGFLPGGEWLYLKLY
                     GVKERETDLISLSLDQLRNNPEFEDWSKKSYFLRYVDPEHHIRLRFQGEPGQLWSAGLA
                     QLNQWAGELREEGLITHMVLDTYLPELERYGGQTLMDLAEQVFDVDSRWVIAYMAGIRS
                     KAFNLDIEIAAVINIIHYLSSFGLTIQEQVDWLEGRIDSKPYMKAFRDIKKALITAVES
                     EYEWIRQADTATQVALLALVEKRQAMIQQYAQAITLAENNHELTNHANDILGSIIHMHL
                     NRLLGVNREREMKCMALAKHTAANLLHRKGVRHVTV"
     aSDomain        complement(12425..12709)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FGY93_RS00485_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.50E-19"
                     /identifier="RREFam001.1"
                     /label="FGY93_RS00485"
                     /locus_tag="FGY93_RS00485"
                     /protein_end="277"
                     /protein_start="182"
                     /score="60.7"
                     /tool="antismash"
                     /translation="VFLNRTVMIKGDRAKLPFRPKHGAAETDDSAEMFSSIRLTDVVRL
                     TFEAAEHPIQVMELKELLLKAFPDATTEIIAHFLQQLVEQEFILSELRPP"
     gene            complement(13230..13907)
                     /locus_tag="FGY93_RS00490"
                     /old_locus_tag="FGY93_00490"
     CDS             complement(13230..13907)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820474.1"
                     /locus_tag="FGY93_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00490"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_016820474.1"
                     /transl_table=11
                     /translation="MKQKFMVISSFKKIKHFFETLSTPENIQIMFYDSLYQALPDIDEQ
                     CIGVALNQDHVTLEDLSHWHTIKEKFTVPFIFLSYHCDDKRQLDLLKQLLSMASSEYGL
                     ERDQEAISLSPNVIFDPAGKVIWKQGHEHMLTMMEFRLLMYLLTAKECASTIDHIIDRV
                     WGVDAFTTSNTVYVHIRKLREKIEDDPSHPKILVTCHGIGYRLNIFPKNLEVASCEETT
                     ALH"
     gene            complement(13958..15223)
                     /locus_tag="FGY93_RS00495"
                     /old_locus_tag="FGY93_00495"
     CDS             complement(13958..15223)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820475.1"
                     /locus_tag="FGY93_RS00495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00495"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_016820475.1"
                     /sec_met_domain="LANC_like (E-value: 5.5e-55, bitscore:
                     184.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGDLQERSVEISKNITQKLIDLSYTEKIVHHRNNLSPSRGTAPW
                     NPGWLADGVPGVFVLLAEWGYLKPDQNWAEHVHTQLLYLHRNSLILLPDISLYYGSTGV
                     AYGILLASNNRANYQQLLNQINDYIRTQWVKSPVINTITEFSKQMDVIHGLLGVGRYTL
                     EIPEDDEKMCNLTHQLLDTITHFIPEYIHSVSRGSSTSIHLGMAHGITGILALLVTALQ
                     KKIRVKGLHEAIEYIADFLLIQIQEDQYGLYWPVSSQATSMNKTDNKEGMREIEGWCHG
                     TCGIAWTLFRAGMECSNEEWTKIAEQAMKSVFCLDDELLNALSPTFCHGLAGLLHMAHR
                     FYYFTGNQAALGFADQIALKLMNLYDEELPFGYQDLEGTTHVHNIGILQGATGIALSLL
                     DYGVGKEQPKYSGRWSELFLIS"
     gene            complement(15299..15451)
                     /locus_tag="FGY93_RS00500"
                     /old_locus_tag="FGY93_00500"
     CDS             complement(15299..15451)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820476.1"
                     /locus_tag="FGY93_RS00500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00500"
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_016820476.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.2e-06, bitscore:
                     24.3, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNQFDLDLQVAKNEVAPKEVQPASGLICTPSCATGTLNCQVSLS
                     FCKTC"
     CDS_motif       complement(15380..15451)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNQFDLDLQVAKNEVAPKEVQPA"
                     /locus_tag="FGY93_RS00500_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15299..15379)
                     /prepeptide="core"
                     /locus_tag="FGY93_RS00500_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="5.70"
                     /molecular_weight="2493.9"
                     /monoisotopic_mass="2492.2"
                     /core_sequence="SGLICTPSCATGTLNCQVSLSFCKTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNQFDLDLQVAKNEVAPKEVQPA"
                     /leader_location="[15379:15451](-)"
                     /alternative_weights="2511.9"
                     /alternative_weights="2530.0"
                     /alternative_weights="2548.0"
     gene            15649..17010
                     /locus_tag="FGY93_RS00505"
                     /old_locus_tag="FGY93_00505"
     CDS             15649..17010
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370167.1"
                     /locus_tag="FGY93_RS00505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00505"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_044788202.1"
                     /sec_met_domain="LANC_like (E-value: 7.9e-55, bitscore:
                     184.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDHFVMEACDQLQAKDFSTTIALRLSNPESVYKAVHAEQNISP
                     ETKYHPWGDTSLSHGYPGNIFLLSQCRASDSTYDWNQAIYLNMKHIQASLAKKGLNDVS
                     LYSGWTGIASSVREASNHGEYYSHFLQQIHEWMIPLTEQWLQLNTAQLALHEGMPMQSF
                     DTISGASGIGRYIVMNSTDPSCAPLVEPILQFLTDLTYPIKIHNRYVPGWYSPQKFQFL
                     DRDKSNYAMGNFNCGMAHGIPGPLALLSVAYSSGIEVKGQYQAIETITEWLLKYKNEDT
                     YGYYWPHIVPFEAETASLQLDLKRAREAWCYGTPGVACSLYLAGKALHDEELQKMAVKA
                     CIGAITYEVTKQEMDSSALCHGLAGLLTISWRMWCHSKEPAFIPLIQHLTSQLIDRFQA
                     DSPLGYLDPEPRADSSLAWLTKAGLLEGVAGIASALLSVSENKEMPWDYMLMLS"
     gene            complement(17011..17745)
                     /locus_tag="FGY93_RS00510"
                     /old_locus_tag="FGY93_00510"
     CDS             complement(17011..17745)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370165.1"
                     /locus_tag="FGY93_RS00510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00510"
                     /product="ABC transporter permease"
                     /protein_id="WP_044788203.1"
                     /transl_table=11
                     /translation="MGSILRVEAMKLQWFMVWILIILDAVINSLMGVLELNDLKQFYEP
                     SWLMLYTYAAQFHSMFFYPLYCGIIASLLCAYEHRDGGWKILLSSPYPRQRIYYAKYIL
                     LILILFLDQLTFIVGYFVGGYIAGAPGKIPWLLVLSTGWGGWFGILPLAALQLMLSVKI
                     RNFGASLGMAICCVVPNIVMTGFHSSIGAWFPFTIPYYIMLPQTASYAPRVEPYSLGLI
                     VLFTFLAYLFAGRKMFVNRDWL"
     gene            complement(17759..18466)
                     /locus_tag="FGY93_RS00515"
                     /old_locus_tag="FGY93_00515"
     CDS             complement(17759..18466)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370164.1"
                     /locus_tag="FGY93_RS00515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00515"
                     /product="ABC transporter permease"
                     /protein_id="WP_044788204.1"
                     /transl_table=11
                     /translation="MILQVIKAEGYKLKKICWWLPLIQGCVLTGMTVMEWYLYFRQGPG
                     GVYAGFAVMFMFISFVMLLGGTLLASIMAGTEHDTQTWKQLMAMPVPRSYIYLSKMFWI
                     VILQFGTALITIAGMSLIWVLYTNEPIPWRVMLLQPINASLATLPVLAIQLWLSTLFTN
                     QAFPLAFGIFGSIASLFLARTSILWIKLLPWSYPALSSPLIKGYVIWVIIALCAGVIFT
                     GLGTLQFRKHEFK"
     gene            complement(18463..19386)
                     /locus_tag="FGY93_RS00520"
                     /old_locus_tag="FGY93_00520"
     CDS             complement(18463..19386)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426675.1"
                     /locus_tag="FGY93_RS00520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00520"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_044788205.1"
                     /transl_table=11
                     /translation="MSEYVIHTQQLTRRFGKREFVKQINLQVPEKQIYGFLGPNGAGKT
                     TTIRMLLGLIKSTSGEIEIFGKKLKDHRMEILKDVGSLVESPAYYAHLSAYRNLEIVTT
                     MRGLPTRKIHKVLDLVRLSKDAYRPVKGYSLGMRQRLGIAMALIADPKLLILDEPTNGL
                     DPSGIQEIRELIMSLPDAYGMTVLVSSHLLSEIEQIATYVGIINQGEMIFQGTMKELTD
                     KSKPQLFIETQNPVQAAGALMQHGWIAGAESLEQKEVITPIVDRQQSSEMIKVLVEHNH
                     PVYRVREKKKTLEEIFLELTGKERSL"
     gene            complement(19532..20467)
                     /locus_tag="FGY93_RS00525"
                     /old_locus_tag="FGY93_00525"
     CDS             complement(19532..20467)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686784.1"
                     /locus_tag="FGY93_RS00525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00525"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_228552495.1"
                     /transl_table=11
                     /translation="MNIDLFWIGLGIVQSLVFIVVYGWYIGKPLVYVIKWIGNIATGEF
                     QAPLSELELPDRKKNQRNNYKPPYQLYKEVFEQMNILSAQLRSNEEERIEIEKRKQQWV
                     AGVSHDLKTPLSYIEGYAAMLTTQEYDWSDEEKRSFSMAISEKVTEMKQLIQDLNASMQ
                     IKEGALPIQLKKKDIVEFLRNTVIDIANHPSAEQYEFSFMSLEAVCTMPFDSKLLGRAL
                     KNFLMNAIIHNPSGTHISMDVNKESDKLHISIEDDGKGMNPTECIQVSHSKEHGISIAK
                     SFIEAHNGTLHILPGSKKGTRVEITLPLNM"
     gene            complement(20599..21318)
                     /locus_tag="FGY93_RS00530"
                     /old_locus_tag="FGY93_00530"
     CDS             complement(20599..21318)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686783.1"
                     /locus_tag="FGY93_RS00530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00530"
                     /product="response regulator transcription factor"
                     /protein_id="WP_044788207.1"
                     /transl_table=11
                     /translation="MEEIAVLIVDDEQGLRDMLTTVLKKEGFLHVKHAATGQEALQIVM
                     ESRIDVIVLDVMLPDRDGFEVCRQMRIYTEAPILFLTARDTDLDKLMGFGIGGDDYITK
                     PFNPLEVVARMKARMKYRKVTTADMKPALRTLDFGYFCLELESGVLYVQDQEVDCPARE
                     WLLLVFLCKHPNRIFSVRQLYEAIWSETFLGDEKTVVIHISRLRKKIEPDPKHPQFLVN
                     VRGLGYKMISVKRGEQE"
     gene            21482..22648
                     /gene="yhbH"
                     /locus_tag="FGY93_RS00535"
                     /old_locus_tag="FGY93_00535"
     CDS             21482..22648
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yhbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370159.1"
                     /locus_tag="FGY93_RS00535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00535"
                     /product="sporulation protein YhbH"
                     /protein_id="WP_044788208.1"
                     /transl_table=11
                     /translation="MTEPRQPYSFVVSREDWSLHRKGYQDQQRHQQKVKDVIKQNLPDL
                     ITEENIIMSDGQQIIKVPIRSLDEYRFIYNYQKQKHVGQGDGDSQVGDVIGRNPASQKP
                     GKGEKAGDQPGHDIMETEVSIEELEDMLFEEMELPHLQQKDKDQIEVESIVFNDIRKKG
                     MQANIDKKRTILENLRRNAREGNPGIHHISPDDLRYKTWEEKTVPQSNAVIIAMMDTSG
                     SMGSFEKYCARSFFFWMTRFLRRQYEKVEIVFLAHHTEAKEVTEEEFFTRGESGGTICS
                     SAYLKALEIIDKRYPPSTYNIYPFHFSDGDNLSSDNERCVKLIEELMKRSNMFGYGEVN
                     QYNRSSTLMSAYKNIKADQFMYYVIKEKGEVYQALRTFFRKREGGTVG"
     gene            22645..24090
                     /locus_tag="FGY93_RS00540"
                     /old_locus_tag="FGY93_00540"
     CDS             22645..24090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686782.1"
                     /locus_tag="FGY93_RS00540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00540"
                     /product="SpoVR family protein"
                     /protein_id="WP_126666747.1"
                     /transl_table=11
                     /translation="MSTDQKELEYAISEIMEIANGFGLDYYPMRYEICPADIVYTFGAY
                     GMPTRFSHWSFGKTFHKMKMQYDFGLSKIYELVINSNPCYAFLLDGNSLVQNKLIVAHV
                     LAHCDFFKHNARFSASNRNMVESMSATAERISSYEMEYGSKAVESFIDSVLAIQEHVDP
                     QLIKPRHLDKQRYMELKIKEQKEPKKHQHPIGPYDDLWSLDTVKQHDSAETEGIKVRQF
                     PPEPEKDIVWFIQEFSEVLEDWQRDIMTMLRDEMLYFWPQMETKIMNEGWASYWHQRIV
                     RELDLTGDETVEFAMLNASVVQPSKQSLNPYYLGLKIFEDIEKRWDNPTREEQERQGRK
                     PGEGRAKMFEVREFDSDTSFIRNYMTKQLTEDLDLYVFEKRGPDWKITDKSWENIRDQL
                     VFSRVNGGSPYIVVEDGDYLHTGELKLKHQYEGIELDLKYMERTLPYVYQLWGRTVHLE
                     TMIEGKLALFSYDGKKHHRKFVQ"
     gene            complement(24159..25340)
                     /locus_tag="FGY93_RS00545"
                     /old_locus_tag="FGY93_00545"
     CDS             complement(24159..25340)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820485.1"
                     /locus_tag="FGY93_RS00545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FGY93_00545"
                     /product="WD40 repeat domain-containing protein"
                     /protein_id="WP_117290188.1"
                     /transl_table=11
                     /translation="MMKQNLDNYGQKNGFPRLKYPYARFFRHKVTGLLMTGLIAGGLLS
                     GCGIKSAGETIPTSGMKPGQKLTVIDMGAARQQVSDELVVQSIDRLGDVYARSWLSDEE
                     LIVERQNQLWIHNVKTNKERVLTPGRNALQLLAVVSPDQRHVFFTEGSASSKYDIQGYI
                     LELSSGKVTSVGQLDMTNEVSWGDKDHLITGTPDGKIHLIGLNGKAEELSFQDPNHSEL
                     IAHVEKVGNDIFYTGNDKQGYPVLNRFSLNHPQAVTIAEGAMSFAVSLDGKSIAIEKRK
                     WNTSEPARMIILDEQGKEKGIVGQGTLMSRGSWSSDGTKLAFSIYDEDQQGMRGLYVFD
                     QSTGKTTPVTTDIQSYDSPTVWSPSARFLSMYQNISEGGKQLNQSYIVEFKKK"
     misc_feature    26529..26543
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 20.57"
                     /tool="antismash"
     misc_feature    26594..26611
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.88"
                     /tool="antismash"
ORIGIN
        1 aaaaattcaa aagccttcaa cctcacgtaa aaagtgaagt tgaaggcttt tgccatacat
       61 acgtattacc agcctacgac cggtatgcaa cttgcccgtt cacaacggtc attcgtacct
      121 taacatcaag caaagcttgg tgactttccg atacatcgcg gtcaataacg gtaaagtcag
      181 cggctttgcc ttcagcgatt gtccctcttt catcagcttc cccagccgct actgcgcttc
      241 ccatagtaaa cagatgaatg gcttcgtgaa catccagctt ctcagcggga agatagccct
      301 catgcatttc ttccggcttg gcgcgagtca ctgccgcatg tatacccaga aatgggttta
      361 ggggctcgat cggtgcatca ctgcctccag cacacggaat gcctgcttgc agcagctttt
      421 tccaggcata taaatactcg gtccgttctt tcccaacccg atccagcacc cagggaaaat
      481 cgcttgcgac aaaacgaggc tggatgtctg caatcagcgg cagcttcacc attcttttga
      541 ccaaatcagc ccgtagcacc tgcccatgaa tcagacgatc cggcaacccg ctttcttccg
      601 ttagtccatg ggcctccatc gctgtcaaaa tcatgtgcgc cgccccatct ccgatggcat
      661 gtacagccac tggaaagcct gcggctctgg ctgctgccac catctgattc agctctggct
      721 gcggttggat ggccattcca cacgtatgtg gagcatcact gtaaggttcg gataataaag
      781 ccgttcttcc accaatagcg ccgtcagcaa acattttaat cgcaccgatt ttgaaccact
      841 catttccggt acctgcacag agcttctgta ctttcacttc ttccataaat ggatgataga
      901 tgagctggtg tgtacgaaaa gcaagacctt cttctcgcag ctccttgtaa attcgctgca
      961 tcgtctctac gctgcccaaa aaacgtaaat cctccgtgtg cgcagcagtc agacccagcc
     1021 gtagcgcatc cagacaagcc cgccggatcg tatccttctt cgccgaataa tccggctctg
     1081 gctgcacgct tgtaaaggca aaggatgctt cctcataaat caatccattt aaccgtccct
     1141 ctgcgtctcg tccataggct cctgaagccg gatcaggggt gttctcgtga atacctgcac
     1201 gccgaaatgc ctctgaattg gccaaaaacg tatgaaagca cgtacgagtc agatataccg
     1261 ggtgctgatc tgtaatggca tccagctcag ctatatttgg aatttcaaca ggaataaacg
     1321 cgttttcgtt ccaattaagt cctaaaatcc actctcccgg cggtgttaca gcgacccgct
     1381 tgcgcagcat agccagcatc tcgtccttgg aagtagctga tgtgaaatcc agcatagcca
     1441 gcttcatacc atgcatagac aaatgcatat gggcatcggt taagcccggc agtacattgg
     1501 caccctccca atccaccgtc tcgtactcct taccggacaa ctgcaattca agctcccggg
     1561 catatccaat ggcctgtatg cggccatgct gtacaacgat ggagtctcct ttggaagccc
     1621 agtccccata taacctgccg tgcttgaaca aaacgaatgt caacgccact catctccttt
     1681 tctccaacta tatgcttgat ctgctgcata ttacgccaag gttgccactt ccaaacgtag
     1741 tgtatttata tctacctgct gtacctcctg cgcaaagtga tcatgagctg cacagacagc
     1801 cattttataa tctgggtcta gctcatactg cttaaaatga caatactcag tagtaaagcc
     1861 ctctgtcgtg aaacctatag acggtcgtgc ttccaactcg aatgaaaaag actttaacgg
     1921 cagcgtcagc ccctgccctt cggccttcac aaaactttcc ttgagcgtcc aaagatcgta
     1981 aaaataggat aaacgactct ctgcatcctg ctgcattaat gcatcgtact ctgtgtctga
     2041 aaagcatacc ctgcctacct caaaatcaat aggacggagc tgttcaatgt caataccaag
     2101 cgggtgatca tcaatggcgc atactaccca ttttcccgaa tgggaaacat taaaatggaa
     2161 tgccggcgca ttcaacaagg agggcttgcc aaaagcattg tatgtaaact gaaggctggc
     2221 atttggtatt tttaattgcc gacaaaccaa ccaccttaac agcacatcgg cgtataaccc
     2281 cctcaaagcg tcttctcgat gtaaaaaacg atccaacttg tgctgttttt ccagtgaaac
     2341 ctgatttacc agtaattcat aatgttcctc agcctccggc ttgcttgtat caatcgcgta
     2401 tatttccatg gtcgcctcct gtatacctaa tggatattag ccagtttgta acactcacca
     2461 gtcgattgaa gtctgttaaa ttaggatgac acttgccata tacatggtca atatactact
     2521 ctagcacttt caattcaata tggatacaat tgggataagc agctctatca aaactacttc
     2581 atagacccta ttaatgaaag cgctttaaaa taaccataca gaggaggacg aaacaatgaa
     2641 atatgatttt gcccgcttgc tgtgtattat gctcactatt ttgctttcgt taagcatttt
     2701 tcagatgttt tcacctaaga tcgcttcagc tgcttcagcg aatgtagtaa atggcattca
     2761 gtttaaagat acagatggaa acgtggtcca tgcccatggg ggcgggatga ttaaagtgga
     2821 cggttattat tattggtttg gtgaaaatcg taatccgaat ggaacattca aggcggtctc
     2881 cgcctatcgt tcctctgatt taaaaaattg ggagtttcgt aaaaacgtgc tgaccagcag
     2941 ttcggccgca gagctgaatg tatcgaatat tgaacgtccg aaagtgattt acaacgaaaa
     3001 aacacgcaaa tacgtattat ggatgcacaa ggaaaacggg attaattaca acgaagcccg
     3061 agtggcagtt gcctcatccg ataccgtaga cggcgattat acgtatcagg gcagcttccg
     3121 tccgctggat tatgattcgc gcgatatgac cgtatacaac gataacggta ctgcatacct
     3181 gatttcggct acccgtgtaa acgcggatct gaacgtttat cgtctgacac cggatttcct
     3241 tcaagttgaa tcgctggtga ctacactttg gccaggacaa tatcgtgaag ctccagcgat
     3301 gttcaaaaaa ggagacgtct acttcctgat tacatccggg gcaaccggct ggaatcccaa
     3361 ttaggccaag tatgctaccg catccagcat tgaaggaact tggagcaata cgatgaactt
     3421 cggggatagt acaacctatg gttcacagtc ggcctacgtc attcctgttg aaggtacgca
     3481 gacgacctcg tatctgtatt tgggcgaccg ttgggctggg gcgtggagtg gtcctgtgca
     3541 ggattctcaa tatgtatggc tgccgctgcg ttttccaacc gcgacctcat tagctatgga
     3601 ttggttcgac agcattaata ttgataccgc cagtggtgtg gtggagggcg taactacgcc
     3661 gatggtcatc gacccggata gttattatca gctggtaagc cgcaagagca acaagtcgct
     3721 aggcatcatt ggcaatgcga cgacagacgg agcagattta gagcagcgtg cgaattccgg
     3781 agcgccaagc cagcaatggc agcttaagga tgcaggcggc ggatattata aaattgtgaa
     3841 tcggaacagc gggaagctga ttggtgttga aagcggtgct acagcagacg gcgcagttat
     3901 tgaacagtgg aatgatggag gctggtccag ccagcattgg cagctcgtat ccgtaaccgg
     3961 aggctattac aagctgaaaa atcgggcaac gggcaagcta atcgacattt ccgaaggtgc
     4021 cactgccgat ggagccaaag ccattcaatg gggcgataat ggcgggacga accagcattt
     4081 ccgtgtagtc aaagtggaat agctcagatc cttatcaaaa ggagccgtca tccgaacaga
     4141 tcgtagtgat ctctaacgga aaacggctcc tttttatgct aaaacggtaa aatgggtgat
     4201 gtctagtaca ctacacttcc cacggaaaat ctgtcgtcag aaaactagcc agctgcttgc
     4261 tttcttccct ccgctgacgc cgtatggctg cgcgcgatgg agccgtctgg tgtaattgta
     4321 tttgctcctc tgtttccgga atcacctgtg ggacggtcac tttacgattg ttctcgtcca
     4381 atgccacaaa ggtcaggaag gcggtagctg caattttgcg atcaccagtc atcaatccct
     4441 cgcgaatcac ttttacgaac acctccattg agctgcggcc tgtccaagtt acgaacgctt
     4501 ccagcgtgac agaatcgctc gggtggatag gcagcaaaaa atctaccgaa tccgtcgagg
     4561 ctgtaactgt gttcgtacgg cacagcttgg cggcagcaat agatgcgata tcgtcgatat
     4621 acgacatcaa tcggcctcca aagagcgtgt tatgattgtt gatatcgttg ggaaatactc
     4681 gggacgtctt aaagcagtag gtttctcgga tgtacttgct ttccatgggt tctttcctct
     4741 cttttcctcg ttgctctctt tttatatctc aggattttgc agaatcctgt gtggaagtct
     4801 gttgtagact atgttaatca tcccactaat ccgcataata aatcaataca taaaaatcgg
     4861 catcctcatc cgaatcatta cgataggtat ggatatcaga tccttgaaat tgtacggcgt
     4921 cccctgcact caattggagc tgttgcccct gcatttcaaa gtacatttcc ccacggatca
     4981 tgagaatcgt ttcctctccc agatgctctt ctgccttgtg tgtaaagcct ggcttcagac
     5041 ttaccgtgaa tacctcgaac ttcttttccg agtgatacgg gaagacaggg taaacaaaat
     5101 agttaccgtc ctcatcaata actggatgca gatctgctct acgaattttg gtgatttgcg
     5161 gcgggtcttc cttaagaaag gtggagaagg atacgtgcaa gccgttcgca atcttccaaa
     5221 gtgtggttac cgtaggatta gatttcccct tctcaatttg agccagcatc cctttgctaa
     5281 cccctgtcag ttcagccacc ttatccaaac taagtcctct agttttccta atttgagcca
     5341 aattagaacc aataatatat tgcattgaat ccaccgaatt atacctcctc gtatcccaaa
     5401 gtctatatat gaagaataca caaaagtgtc cgctgtagct ataatttact gttgacatta
     5461 actataaatg tccttaaact tcacttacta aaacgttttt caaaactatt gtaatatcct
     5521 gaagggggcc gctatcctgt gacttttcca tccctgaaca cccaacaggc gagaaaatca
     5581 acgttgacta tctaggaggg actaaatttg aatccgcaaa cccgcaagtc ccgccacatg
     5641 tacatgatgc agctggcgac aatttttatt ggctttattg tatttggtat ctcggagaat
     5701 ataaaaggtc ctgccattcc acgcattcaa ttcgacttca atctggatga acagcagctc
     5761 ggaacattgt tgtctctaaa cgcacttggt tatttgattg cctgctcgtt caccgctgtc
     5821 cttgtccgta agtggggaat caaggcggtc agcatcattt cttttgcttc catgatcatc
     5881 tcgggagtgt tcatctacct gtcgcacacg tatccgttct tcgcttcgtc ctacttcttg
     5941 atgtatatcg ggaacggcat gctggagatt gcactcgcaa ttttgggggc gaggattttt
     6001 gtgaaaaata ccggcacgat gatgaatttg tctcactttt tctatgggct tagctcaaca
     6061 gtcgcccctt tgctggcgac gggagtcatg tcactgacgg tatttgggca tacgctagac
     6121 tggcggggaa tgtatctggc tatgttgtcg ctctgcctgc tgccgattgt ggccgcgctg
     6181 ctcagcgcct tcccgggaga cgatctgcag catgaggaac ggacctcact caagacccta
     6241 acccgcgatc cggcactctg gatgatggta atgatcctgt cgtttggggt agtctctgag
     6301 ctcgcagttg ggggctggct agtcaacttt ttagagaaag cgtattcatg gagcacggtg
     6361 aaggcgtcca gcatgctctc agcgtttttt cttaccttct cgttggggcg cctgttgctt
     6421 ggtccactca cagaccggat ggggtttgta ctttcgacga ttctattctc cgccttctca
     6481 gcgatatgca cgtttgcagc aatcgcgggt ggggagagac tggcgtttct ctttgccgca
     6541 tcgggtgccg gcattgcaat gatctatccg accgtgatgg cgttcatagc acggagatat
     6601 ccgaaagaca gtgatacagc tattacgttc gtcgtcacac tgatgggcat aggtagtgtc
     6661 attggcaact atgtgatcgg ctgggtaatc gaaggggtca agatagtcta cggagcaacc
     6721 actgagcttg gcatactgcg cgggcttcag gcgggatatg gagttattgg tctatgtgca
     6781 gccatctgcg cggtctcggg aatgattctc tacggatatc tgaaaaaacg gcaagagctt
     6841 atataagcca ccaccttagg gttgtcccat aagtcatgaa ctgactgggg cgcccttttt
     6901 ttacgaacta cttgttcgct atagggatta ttcaatataa catacaattg tataatatat
     6961 tgatacttcg caatttccgt tatatactat tataaaattt atacactggg ggtaaggtta
     7021 acatgtccat agcttcggaa ttgagcggaa cgaagcccga ttcactgagc gttttacaag
     7081 gggttaaaga ttgtattcct acactgcttg gttatgtatg tattggattc gcagctggca
     7141 ttgtgggcgc ttcatcaggg gttagcacca tggaaattgg tctgatgtca gcgcttgtat
     7201 acgcaggcgc ctcccagttt attatgtgct cgatgctggc ggcagccagt cctccgtctg
     7261 tcattatttt aacgacattt attgtgaatg ctcgccatct gcttttaagt gcgtcattgg
     7321 ctccttactt ttctaaatac tcactgtgga aaaacatagg catcggtatc cttttgacgg
     7381 atgaatcctt tggggtagcg tcggataaat tggctaaagg cgggcaggtc agtgaccgct
     7441 ggatgaacgg acttaatatt acagcttatc tcgcttggat tgcttcctgt gtggctggtg
     7501 gagtgctagg gaattggatt tcccagccgg aagcttttgg tctagacttt gccttacctg
     7561 caatgtttct ggccctactc atttcccagc tccaaagtgt ccagacctcc aaactcaagc
     7621 atcgcctgct gcttgtgcta tgtatggccg ttctaatgta ccttttgtcc tggtgggtgc
     7681 catcacatat cgcagtcatt gtagcgacca tgatcaccgc aacgattgga gtgttaactg
     7741 acaaatgagt attagtccca atgtcctgta tatcattatc ggcggtatga ttgtcacggc
     7801 aattccgaga atcatcccct tcgtcgtgct gcaaaaactg acgttgccca aacctgtgtt
     7861 acagtggctg tcctacatcc ccatttgcat cttcacggca ctggtcatgg aaaatctgct
     7921 cgtacgaact gaaacctcgg tcactcttaa tgggcaagtg cttatagcgg tccttcctac
     7981 gctggtgacc gctttgtgga gcaaaaattt gctggctact gtggttgtgg gtattgtgag
     8041 tatggctgta gttcgagttt tgtggttggg atagaaaatc ccctcctaaa ataggagggg
     8101 atttgtcctt tcttacgatc cgcctgtcgc ctttaccaac ggaggtgaca gcatctcttg
     8161 ctcaagttca ctttctcctt gtgaaagata cgaagatgct tgtagcctga acatttcagc
     8221 gtatactccg tccatatcca ttaagtgttt atgactgccc gcttccacaa ttctgccctc
     8281 cttcattaaa ataatggtat ccgccatacg tgcggaggac aatctgtgtg aaataaatac
     8341 tcctattctc tcgtgaacaa gttgatcaaa tttttgaaaa acttccttct ctgcgtgtgg
     8401 gtctaaaaaa gaactcggct catccaacac atagatatca gcatttctca taaaagccct
     8461 agctattgct atgcgctgcc actgccctcc agatagctgt tgtccatctt caaaccattt
     8521 tccaagcaga gtgttcagtt tttctggcag accagctatc aaatctacaa tgcctgcctt
     8581 atcaatagct gtccaaatgg cctcatcatt ttctctggca gccacatgac caaagcctat
     8641 attatcccta acagacatct cataatgtac aaagtcctga aaaacgacgc ctatctttcc
     8701 cctaaagctg tctttatcca attcgtgtat tgagtgtcca ttaattaaga tttctccttc
     8761 aaaatcagaa tacagatgag tgagtaactt cacaattgtt gatttacccg atccatttct
     8821 ccctacaatg gctagcttct ctccttgatg aagagtaaag ctaacattag agatggcatt
     8881 ctcctccgtg ttaggatatc taaacgatac atttcgaaat tcaatactgt gtatagcgga
     8941 caaaggcaag tgttgaactg acttttgcat tttcgtttcc tccggcatat ccagaaagtc
     9001 aaaaagctgc ttaatataca agttattttg acacagactt aaaatacctt gtacaatgct
     9061 ctgcgacgtt gactgggtta acgtgatacc ttgaattaag ctcaccaggt tccccactaa
     9121 aatttgacca acataagtgg cttgtatggc catgaaaata ataaatgcgc atgcaccctg
     9181 attcacaatc tgaaatgcaa gagaagtata ggatctacga accgccagca ctttatcctc
     9241 acgataaaac ccttcgagta ttgttttata cctttttcgc agataatctc ccagttgaaa
     9301 tattttcact tctttaaaac tattatctct cgtcaccaaa aaagacaagt accaggattc
     9361 gcgttgtctt cctgctcttt gaaagtgaac attaaattct ctttgcccaa tgcgtaaaaa
     9421 ggaatagaat gacaaacatg gaatgagaaa aatgaataaa aacgcccacc atctccacgc
     9481 aataagaata gcacccgtcg aaaataaggt taccacactg ctcataatgg cgaggatctg
     9541 agtaaatatt tcaaatggtc tgtaatctgc ttctccctga gcacgttgaa gcatattttg
     9601 cacatctgca tcctcaaacg actgcaaaga catcttttgt gctttttcaa taattctgat
     9661 atttacctgg tttgatagcc ggctttgaaa cattttacga aaaaagcttt ccccaatatt
     9721 gatcagatcg tacagcaaat tgacacctat tagaacacca aaagctataa aaacaggctg
     9781 aaagcttcct cctgacgctc ctgccacaac actattaatt aattccctcg ttgctaaaag
     9841 gatcacagca ggaacggcac ccttcaacaa atttgtaata agtatagcga tcaaaaaagt
     9901 agggtgtgtg tcccaaagca gcctgaatat acgaggccaa aataaaaagg tacgaaatat
     9961 attttggtag gacaaggaaa ccaggtcatt ggtttgtcct ttagactgtg acatggcgca
    10021 ctcctttccg atgcaacagg ttggccgctg tatgctttgc caaagccata catttcattt
    10081 cccgttcccg atttacaccc agcagacgat tcaggtgcat atgaatgata ctgcctaaaa
    10141 tatcattagc atggttcgta agctcatgat tgttttcagc cagggttatc gcttgagcat
    10201 actgttgaat catggcctgt cttttttcta caagtgccaa caaagcgacc tgtgtagccg
    10261 tatccgcttg tctaatccat tcatattccg attctacagc ggtaatcaat gcttttttaa
    10321 tatccctgaa cgccttcata taaggcttgc tgtcaattct accttctagc cagtccactt
    10381 gctcctgaat cgttaaacca aagctgctta aatagtgaat aatgttaatc acagctgcaa
    10441 tctctatgtc cagattgaaa gctttggaac gaattcctgc catataggcg ataacccatc
    10501 ggctatccac gtcaaaaacc tgttctgcca ggtccataag tgtctgccct ccatacctct
    10561 ccaactcagg aaggtatgta tccagtacca tatgtgtgat aagtccctct tcacgcagct
    10621 cacctgccca ctgatttaat tgcgccaagc cagcactcca tagttgacct ggctctcctt
    10681 gaaaccgcag acgaatatga tgctcaggat caacgtaccg caaaaaataa gattttttac
    10741 tccaatcctc aaattccggg ttatttcgga gttgatccaa gcttaaggaa ataagatccg
    10801 tttccctttc cttgactcca tacaatttaa ggtacagcca ttcacctcct ggaaggaacc
    10861 ctctatgaat gcccgaaggg gtataagcca tgaatttttg agaatccatc ttgtggggta
    10921 aacttggaat actcggcttc ccctttattt ttttcttctt gagcggaaac acaaattccc
    10981 ccatatatct tccagcggtc ccatgtagcg gggtatggaa tggatcgccc aaacactcgg
    11041 taagaagcag ttcctgtcct tccctcatct tgctcatctc acgaagcaat tctttgatat
    11101 ggaagagatt gcacaggtcc aataacagtc ggttatctcc catcgttaaa taaacatagc
    11161 gtggcacatt ccactgttct ctccaagtat gaaaaagctc ctcccttgct tgaggctcag
    11221 ttaaatctga aatattcaat gcagccttgc caagcctcca ctgcgcagca ctaataacaa
    11281 tttttccata tacaagtctt ggcaaaaaag gagactgctc tagtggcccc cagtcaaagt
    11341 atgaccatgt gccaagctct ttgttggtga tatcggtcaa gaatctgaat acatgcggtg
    11401 aaagcttgta attaagcata tgggtttgca gggggatgat ttctttaccc aaacgcctgg
    11461 acttgacata gaaacggtcg tgagttgcac ctatcaataa atcatccatg tgtagtgtct
    11521 gctcctcatc tttagaagag gtcgttccgg acacgatttc atattccata aaatttttgc
    11581 tcagtgatat attcgatatt tttccctggt caggcataaa aaccatctct gccaacaagg
    11641 cgtcgggatg aaagcatcgg tgatgatcat aaatatcaga gaatttctga acatactctt
    11701 cactaaacat atccagaaaa cgtccaaaag ttttacctgc ccgattagaa ccggcgctgg
    11761 gcccaagtaa aagcttatag tctcctgaat caactttttc aggtgattcg gcaaatatac
    11821 tgtagtatac ctccatagat tccggggaag tgtcatcatt atcggatatc gtcagctgct
    11881 ccaactgctc atctgaaaga acgatttcta tgtcatggtt ggcaatggca ttcgaaagcc
    11941 attgaaagag aactgcgttg cgtttaaatg cttccatgcc cattgatttt ttctcattgg
    12001 tacgatacgt ctttggtata ccaagtcccc aatcctcatc aaacagttca ttgataggga
    12061 cctcctggta cactccgtac ttttccaaaa aacgatttaa atattcgtcc agttcatcca
    12121 tttttgggga tgaaaacaac ctgcacatga cttcagctcc taatgcaaca tcatcgagca
    12181 catgtctcgg cagcgttact tcttgagcta atttgacatc gacctgtaca ggcgttttta
    12241 cagcaatgat atctagcatt tttccacata gttcccggta ggccttctct ccttctccaa
    12301 tcatgcactg attgtattgt cgtaataaaa tatcaatttc gtgtaaaatg tcagtccaat
    12361 aatcagacat gtccattttt ttaatttttt caaatatgta atgaaaaggt gagtgatcca
    12421 tcagtggagg tctaagctcg ctcaaaataa actcttgctc tacaagctgc tgcaaaaaat
    12481 gagcgatgat ttccgtagta gcgtcaggaa atgccttcaa tagtaattct ttaagctcca
    12541 tcacctgaat cggatgctca gcagcttcaa acgtcaggcg aacgacgtcc gtaagccgaa
    12601 tggaactaaa catttcggcc gaatcatcgg tttctgccgc tccatgctta ggccgaaatg
    12661 gtaatttggc gcgatcgccc ttgatcataa ccgttcggtt taaaaaaacc tttaattgat
    12721 caaatatgac tgggtcagac tccatttttc ggataatctt atatatccat tccatgtcag
    12781 gtctagctct cttcagatgt tgatgatagg tacctatgtc caaatgggta gtatccttac
    12841 aaatcccttg ccccacccct gaaaataatc caaatggagt cgttcgagta gtcatccgaa
    12901 taaaataacg ataaaaacta tttagcgtct tctcatactt ttgtaactct cctttatctt
    12961 ccaaagcatc gtcatcgttc aagtagtgta gaaactgcat aagggacgga gaggccaatg
    13021 aaatagcttc tcgaataaca gcttcacggg acacaagctt tagtcgacga gtgatttcct
    13081 ccaaagaaag atggctatct acatcttgat ccgaaaacac ctcaaaatat tgctctaacg
    13141 gtagtaatgg ggctctgatt agaaaataat cacatgcgct gaaccatcgt tcattcttat
    13201 ctctcggttc tctatgtagg ttatgagcat cagtgtaatg cagttgtctc ttcacaactg
    13261 gccacctcca agtttttagg aaatatattc aacctgtaac cgattccatg gcatgttacc
    13321 agtattttcg gatgacttgg atcatcttct attttctctc tcaattttcg gatatgcaca
    13381 tacaccgtat tagatgtagt aaaagcatca actccccata ctctgtctat aatgtgatca
    13441 atcgtggatg cacactcttt cgctgtaagg agatacatca ataatcgaaa ttccatcatc
    13501 gtcagcatat gctcatgtcc ttgcttccaa ataaccttac cagcaggatc aaaaatgaca
    13561 ttgggtgata aactaattgc ctcctgatct ctttccagcc catattcaga tgaagccatg
    13621 gaaagcagtt gtttgaggag atccaattgc cgtttgtcat cacaatgata ggataggaag
    13681 ataaatggga ctgtaaattt ttctttaatg gtgtgccagt gagataaatc ctctagcgtt
    13741 acgtgatcct gattcaaagc tacaccgatg cactgctcat caatatccgg tagagcctgg
    13801 taaagcgaat cataaaacat aatttgaatg ttttctggag tgcttaaagt ctcaaaaaaa
    13861 tgcttaatct tcttaaagga tgatataacc ataaattttt gtttcatcta atcctcccca
    13921 aaaacacggc ttcagataag cagttaagac agagctttta cgaaattaga aacaattcac
    13981 tccatctccc tgaatattta ggttgttcct tccctactcc atagtccaac aagcttaatg
    14041 caattcctgt tgccccttgc agtattccta tattatgaac atgagttgtc ccctccaagt
    14101 cctgataacc aaatgggagc tcttcatcgt atagattcat caactttaat gctatttggt
    14161 cggcaaagcc taatgcagct tgattaccag tgaagtaata gaatctatga gccatatgaa
    14221 gcaaacccgc caatccatga cagaaagtgg gggatagcgc gtttaaaagc tcatcatcca
    14281 agcaaaatac ggatttcata gcttgttcag ctatctttgt ccattcttca ttgctacact
    14341 ccattcctgc tctgaataaa gtccatgcta tcccacaggt tccatggcac cagccttcaa
    14401 tttctctcat tccttctttg ttatctgtct tgttcattga agtcgcttga gagcttacag
    14461 gccaatacaa accatattga tcctcctgaa tttgaataag caaaaaatcg gctatatatt
    14521 ctatagcctc atgtaatcct ttaactctaa tctttttttg tagggcagtg acaagtagtg
    14581 caaggattcc ggtgatgcca tgcgccattc ctagatgaat cgaagtcgaa cttccccttg
    14641 ataccgaatg tatatattca ggtataaagt gcgttatagt atctaatagt tgatgggtca
    14701 gattacacat cttctcgtcg tcttcaggaa tctctaatgt gtatctgccc actccgagca
    14761 ggccgtggat aacgtccatc tgcttgctga actctgtaat tgtatttata acgggtgact
    14821 ttacccattg agtacgaata taatcattta tttgatttaa cagttgctga taattagctc
    14881 tgttatttga ggcaagcaat attccatatg ctacacctgt agaaccatag tacagagata
    14941 tatcgggtag taatattaaa gaattgcgat gtaaatacaa caactgtgta tgcacatgtt
    15001 ctgcccaatt ctgatcaggt ttcagataac cccactcggc caacagcacg aatacacctg
    15061 gaactccatc agcaagccag ccgggattcc aaggggccgt cccacgcgaa ggtgaaaggt
    15121 tgtttctatg atgaactatt ttttctgtat atgataggtc tatcagtttt tgtgtaatat
    15181 ttttgctgat ctcaactgac ctttcctgca aatctccaac cataattcct ccccctattt
    15241 tataaccggg aaaagacacg gttataaaac cgtgcctttt gtaccttgtt tctcgttatt
    15301 aacacgtttt gcagaaagaa agactaactt ggcaattcaa agtacctgtt gcacatgaag
    15361 gagtacagat aagaccgcta gctggttgaa cctctttagg agcaacctca tttttggcaa
    15421 cttgcaagtc cagatcaaat tgatttttca ttttgctacc tccttttatt ttttacaatt
    15481 ttattataat ttatataatc ttaactagac tttataaaac tcttacatcc atcttaaatt
    15541 tagtgaatgc aattaagata atccctcgtt actttttaga atttttaagg acaactcgcc
    15601 agctttgagc aacaatataa tgaaggaaaa aatgaaaggg gcattcgtat gaaaacggac
    15661 cattttgtta tggaagcatg cgatcaatta caggcaaaag acttcagtac aacaatcgcc
    15721 ttgcgcctga gtaaccctga atcggtctac aaagcagtcc acgcagagca aaatatttca
    15781 cccgaaacaa aatatcaccc atggggagat acttcgcttt cacacggtta tccgggtaat
    15841 atttttttac tatctcaatg tcgtgcttca gactccacgt atgattggaa tcaggcaatc
    15901 tacttgaata tgaagcacat tcaagcttca cttgctaaaa aaggtctgaa tgatgtctca
    15961 ctttacagcg gctggaccgg catcgcttct tctgtgagag aagcctccaa tcatggcgaa
    16021 tactacagcc attttttaca gcaaatacat gaatggatga ttcctctgac agaacaatgg
    16081 ctgcaattga atacagcaca attagctctg cacgaaggga tgcccatgca atcctttgat
    16141 acgatttcag gagcctcagg gattgggaga tatattgtga tgaactcaac cgatcctagt
    16201 tgtgctcctc ttgtcgagcc tattcttcaa tttttaaccg atctcacata tcctataaaa
    16261 attcacaacc gctatgttcc aggctggtac tctccgcaaa agttccaatt tttggatcgt
    16321 gataaaagca attatgctat gggtaatttc aattgcggaa tggcacacgg cattcccgga
    16381 ccactggcct tactatctgt agcttacagt tctggaattg aagtaaaagg ccaatatcaa
    16441 gcgattgaaa cgattacgga atggctgctt aagtataaaa atgaggatac atacggctac
    16501 tactggcctc atattgttcc ttttgaagct gaaacagcct ctttacagtt agatttaaaa
    16561 cgagcaagag aagcctggtg ttacggtact cccggcgttg cctgttcctt atatcttgcc
    16621 gggaaggctc ttcatgatga agaactgcaa aaaatggctg tgaaggcctg tatcggtgcc
    16681 attacctatg aggttactaa gcaggaaatg gactcctctg cattgtgtca tggtcttgcc
    16741 gggttactta cgatctcctg gcgaatgtgg tgtcacagta aggaaccagc gtttatcccg
    16801 cttattcaac acttaaccag tcagctgata gatcgctttc aagccgatag cccacttgga
    16861 tatctggacc ccgagccaag ggcagacagc tctttggcct ggctgacaaa agcaggcctg
    16921 cttgaaggcg tcgccgggat tgcttctgct ttattaagtg tttctgagaa caaagagatg
    16981 ccctgggatt acatgctcat gctatcctag ctacagccaa tccctattca caaacatctt
    17041 tcttccagca aatagatagg ctaaaaacgt aaaaagtaca atcaaaccaa gactataagg
    17101 ctcaactcta ggagcatagc tcgctgtttg cggcaacatg atataataag gaatcgtaaa
    17161 aggaaaccat gcgcctatgg aagagtgaaa gcctgtcata acaatattag gcaccacaca
    17221 gcaaatagcc attcctagtg aagctccaaa attgcgaatt ttcaccgaga gcataagctg
    17281 gagggctgcc aatggtagaa tcccgaacca ccctccccat ccggtagaaa ggacgagcaa
    17341 ccaagggatt tttcctggag cacctgctat atacccacct acaaaatatc ctactatgaa
    17401 tgtaagctga tcaagaaaca ggatgagaat gagcaatata tattttgcat aatagattcg
    17461 ctgacgggga tatggactgc tcaataaaat cttccatccc ccgtctcgat gttcgtatgc
    17521 gcacaaaaga gaagcgataa ttccacaata aagcggataa aaaaacatcg agtgaaattg
    17581 cgccgcatag gtgtatagca ttaaccagct aggctcataa aactgcttca aatcgttcag
    17641 ttccaggact cccattaaag aattgataac cgcatctaat ataatgagaa tccataccat
    17701 gaaccattga agcttcatcg cttccacgcg taaaatggat cccatactac tcctcctcct
    17761 atttgaattc atgctttcta aactgtagag taccgagtcc tgtgaagatg acccctgcac
    17821 ataaagcaat gatcacccat attacgtatc ccttaattag aggacttgat agagccggat
    17881 acgaccaagg taataattta atccaaagaa tactggttcg tgccaaaaac aagctggcaa
    17941 tagaaccaaa tatgccaaat gctaacggga atgcctgatt agtaaaaagc gtagacaacc
    18001 aaagttgaat tgcaagtaca ggcagagtag ccaagctggc gttaatcggc tgcagcagca
    18061 taactcgcca aggaatgggc tcgtttgtat acagcaccca gatgagactc atccctgcta
    18121 tcgtaatcaa ggcagtacca aactgcagaa tcacaatcca aaacattttg gataagtaga
    18181 tgtagcttct aggaaccggc atggccataa gctgcttcca tgtttgggta tcatgctctg
    18241 tacccgccat aatgcttgct agaagtgtac cgccaagcag catcacaaac gagatgaaca
    18301 taaacataac cgcaaaacca gcatagactc ctcccggccc ctgacgaaag tagagatacc
    18361 attccatgac agtcatccct gtaaggacac agccctgtat tagaggaagc caccagcata
    18421 tttttttcag cttatatcct tccgccttga taacttggag tatcataaac ttcgctcctt
    18481 acccgtcagc tccaggaata tttcctccaa tgtttttttc ttctccctta cccgatagac
    18541 ggggtgattg tgctctacta acactttgat catctccgat gattgttgcc gatccacaat
    18601 aggagttatg acctcttttt gctccaagga ttcagctccg gcaatccatc catgctgcat
    18661 cagggctcca gcagcctgaa caggattttg ggtttcaatg aataattgag gcttgctttt
    18721 gtctgtaagt tctttcatcg ttccctggaa tatcatttcc ccttgattaa taatccctac
    18781 ataggttgcg atctgttcga tttcacttag tagatggctc gaaaccaata ccgtcattcc
    18841 gtaagcatca ggcaggctca taattaactc ccgaatttcc tggataccag acgggtccaa
    18901 accattcgtc ggttcatcaa gaatcaacaa tttgggatca gcaatcaacg ccatggcaat
    18961 tcctagcctt tgcctcatcc ccaaggagta tccttttacc ggtcgatacg catctttgct
    19021 taatctcacc aaatccagca ctttatgaat ttttcgggtc ggcagcccac gcattgttgt
    19081 aacgatttct aaatttcgat atgcagacaa atgggcataa taggcaggtg attcaaccag
    19141 agaacctaca tcctttaata tttccatgcg atgatccttg agctttttcc caaaaatctc
    19201 aatctccccg gatgtggatt taatcagccc gagtagcata cgaatcgtgg tcgtttttcc
    19261 cgccccgttt ggtcccaaaa atccgtaaat ttgcttctca ggtacctgga gatttatttg
    19321 tttgacaaat tctcgttttc caaaacgcct ggttagctgc tgtgtatgta ttacatattc
    19381 agacatttcc tgatctcctc tcgactttta atgctgaagt tttagttaca tacagtttac
    19441 agaaggaaag ttaacatcag gtaaacagtt cctaaacaac aggcaaaaaa acgagcggac
    19501 tccaaaatgt gagggcaaag atgttaaaga gttacatatt tagcggcaaa gtaatttcca
    19561 ccctggtacc ctttttactt cccggaagaa tatgaagcgt tccgttatga gcttcaataa
    19621 agcttttggc aatagatatg ccatgctctt tggaatgaga cacctgtata cattcagttg
    19681 gattcattcc ttttccatca tcttcgatcg aaatatgaag cttatcgctc tctttattta
    19741 catccattga aatatgtgta cctgaaggat tatgaatgat tgcgttcatc agaaaatttt
    19801 tcagcgctct acctaataat ttactatcga agggcatggt acatactgcc tccaatgaca
    19861 taaaagaaaa ttcgtactgc tcggccgaag gatggttagc gatatctatg actgtattgc
    19921 ggagaaactc cacaatgtcc ttcttcttca gctggatcgg caaggcaccc tccttgatct
    19981 gcatagaagc attcaaatcc tgaattaact gcttcatttc cgttactttc tcactgatag
    20041 ccatactaaa gcttcttttt tcttcatcgg accaatcata ctcttgagta gtcagcatgg
    20101 ctgcatatcc ttcaatatag gataatggcg ttttgagatc atggcttacg cctgctaccc
    20161 actgctgttt tcgcttttct atttctattc tctcttcctc attactgcgc aattgagcag
    20221 ataagatgtt catttgttca aaaacttctt tatacaattg atacggaggc ttataattat
    20281 ttctctgatt ttttttgcga tctggcagtt ctagctcact tagcggtgcc tggaattccc
    20341 ctgttgctat atttccaatc catttaatta catacaccaa gggtttgcct atataccatc
    20401 catagacaac tataaacaca aggctctgca cgattccaag tccgatccag aagagatcaa
    20461 tattcatatt atgagatgta ccaaatgtac tttttataaa aatatatata acagtacaga
    20521 taagaaaaca aagaacatag gctagagcaa aacataatgt tacttttata aaacgaaagg
    20581 acatcttgac gagagagttc attcttgctc ccccctcttg actgatatca ttttataacc
    20641 tagccctctt acattaacta aaaattgcgg gtgcttggga tcaggttcta ttttttttcg
    20701 caaacgagag atatgaatga ctactgtctt ttcatcacca aggaaggtct cgctccatat
    20761 tgcttcgtat agctgacgca cactgaatat acggttagga tgcttgcaca aaaataccag
    20821 cagcagccat tcacgtgcag gacaatcgac ctcttggtct tgcacataca acacacctga
    20881 ttccaattcc agacaaaaat atccaaaatc taaggttcgt aaggcaggct tcatgtccgc
    20941 tgttgtcact tttcgatatt tcattcgagc tttcatacgt gcaacgactt ctaacggatt
    21001 aaacggtttg gtaatataat cgtccccacc aataccaaat cccattaatt tgtccaaatc
    21061 tgtatctctt gccgtcaaaa aaagaatagg agcttccgtg tatatacgca tctgacgaca
    21121 cacctcaaat ccatcacgat caggaagcat aacatcaagc acaatcacat caatacgaga
    21181 ttccatcacg atttgcaacg cttcttgacc cgtggctgca tgcttaacat gtagaaaccc
    21241 ttcttttttt aaaactgttg tcagcatatc tcgcagtccc tgttcatcgt ctacgataag
    21301 cactgcaatt tcttccataa ccaaggttct ccattctttt tttacatttt ttactttcat
    21361 tataaaagca aacgggcaga atttaaatcg agttccatca catatcgtac atccccgtga
    21421 atatacttaa taaccaacaa ggccaaactg tgccgtgtat ccacttgggg ggtgcctaac
    21481 aatgacggaa ccacgccagc catattcatt cgtcgtatcc cgcgaagatt ggtcgctgca
    21541 tcgcaaaggg taccaggacc agcaacgcca tcagcagaag gtcaaagatg tcattaagca
    21601 aaatctaccc gatctgataa cggaagaaaa tattataatg tcggacggtc aacagattat
    21661 caaagtgccc attcgcagtc tggatgaata tcgcttcatt tataactacc aaaagcaaaa
    21721 gcatgtaggt caaggggatg gcgacagtca ggtgggggat gtcatcggac gtaatcctgc
    21781 ttcccagaag ccaggtaaag gtgagaaagc aggcgaccag ccaggacatg atattatgga
    21841 aactgaagtc agcatagaag aactcgaaga tatgctgttt gaggaaatgg aattgccgca
    21901 tttgcagcaa aaagataagg atcaaattga ggttgaatct atcgtattca atgatatacg
    21961 taaaaaaggc atgcaagcga acattgacaa gaagcgaacg atactcgaaa atctgcgccg
    22021 caacgctcgt gaggggaatc cgggcatcca tcatattagt ccggacgatc ttcgttacaa
    22081 aacatgggaa gagaaaaccg ttccccaatc caatgctgta attatcgcta tgatggacac
    22141 ctcaggcagt atgggatctt ttgaaaaata ttgcgcccgc agcttctttt tctggatgac
    22201 tcgctttttg cgtcgccaat atgaaaaggt ggaaattgtc tttcttgcgc atcataccga
    22261 agccaaagag gttacggagg aagaattttt tactcgcggt gaaagtggcg gcacaatctg
    22321 ctcttctgct tatttgaaag cattggagat tatcgacaag cgctatcctc cttccactta
    22381 taatatttat cccttccatt tctccgatgg cgataaccta agctcagaca atgaacggtg
    22441 tgtgaaacta attgaggagc ttatgaagcg cagcaatatg ttcggctatg gagaggtgaa
    22501 ccaatataat cgcagcagta cgctgatgtc agcctacaag aatattaagg cagatcagtt
    22561 tatgtactat gtcatcaagg aaaaaggtga ggtataccaa gccctacgca ccttttttcg
    22621 caaacgggaa gggggaacgg tgggatgagt accgaccaga aagagctgga atacgcgata
    22681 tcagaaatta tggagattgc aaatggattc ggtctcgact attacccaat gcggtatgaa
    22741 atttgtccgg cggatattgt atacacattc ggtgcgtatg gtatgcccac gcgcttcagc
    22801 cactggagtt tcggaaaaac atttcacaag atgaaaatgc agtacgattt tggattgagt
    22861 aaaatctatg agctggtcat caactccaat ccctgctacg ctttcctgct ggatggaaat
    22921 tcgttggtgc aaaataaact gattgtcgct catgtgttgg cgcactgcga ctttttcaaa
    22981 cacaacgccc gcttctcggc ctccaaccgc aatatggtcg agagcatgtc tgccaccgca
    23041 gaacggatca gcagctatga aatggagtac ggctcaaagg ccgtagaatc cttcattgac
    23101 tctgtactgg cgatacaaga gcatgtagac ccacagctca tcaaacctag gcatctagat
    23161 aaacaacgat acatggaact caaaatcaag gagcaaaaag aacctaaaaa acaccagcat
    23221 cccatcggac cttacgatga tctgtggtca ctggacacag taaagcagca tgattcggcg
    23281 gagaccgagg ggatcaaggt acgccagttc ccaccggaac ctgaaaagga tattgtctgg
    23341 tttattcagg aattctccga ggtactggag gattggcagc gggacatcat gacgatgctg
    23401 cgggatgaaa tgctgtattt ctggccccaa atggagacca aaatcatgaa tgaaggctgg
    23461 gcctcttatt ggcatcaacg gattgtcagg gaactggatc tgactgggga tgaaactgtt
    23521 gaatttgcca tgctaaatgc ttccgttgtg cagccttcca agcaaagctt gaatccatat
    23581 tatttgggac tgaaaatatt tgaagatatt gaaaagcgat gggataaccc gacccgtgag
    23641 gagcaagagc gtcaaggacg caaaccgggc gagggccgag ctaaaatgtt cgaggtgcga
    23701 gaatttgatt cggacacctc ttttatacgc aattacatga ccaagcagct aacagaggat
    23761 ttagatttgt acgtgtttga gaaacggggg ccggattgga aaattaccga taaatcctgg
    23821 gaaaacatac gggatcagct tgtgttctca cgcgtaaatg gaggctcccc ttacatcgtc
    23881 gttgaggacg gagactacct gcatacgggc gagttaaagc tcaagcatca gtatgaaggc
    23941 attgagctgg atttaaaata tatggagcgc acgcttccat atgtatatca actgtggggg
    24001 cgtactgttc atttggaaac gatgattgag gggaagctcg ccttattttc atatgatggg
    24061 aagaaacatc atcgcaagtt tgtgcagtga cccacaatcg aatagccagc ctaatttaaa
    24121 aaaggtgcat tccgaagaag gaaatgcgcc tttttttact actttttctt aaattcgacg
    24181 atgtagctct gattcagttg ttttccacct tccgaaatgt tctggtacat ggataaaaac
    24241 cgggcggaag ggctccacac tgttggactg tcataggatt gaatatcagt cgtgacggga
    24301 gtggttttac ccgtggactg gtcaaataca tatagtcctc tcattccttg ctgatcctca
    24361 tcataaatgg aaaaagcaag cttggtcccg tcgctggacc agcttccacg actcattaaa
    24421 gtcccttgac ccacgatccc tttctctttg ccttgttcat ccaaaatgat catacgggct
    24481 ggttcggatg tattccattt ccgcttttca atggcaatag atttaccatc aagcgacaca
    24541 gcaaaagaca tggccccctc tgcaatggtc acagcttgag gatgattgag agagaaccga
    24601 ttcagtaccg gatatccttg tttatcattg cctgtataaa atatgtcgtt acccaccttc
    24661 tcgacatgag caattaattc tgagtgattc ggatcttgaa agcttagttc ttctgctttg
    24721 ccgttcagac caatcagatg tatcttaccg tctggtgtac ctgtaatgag atgatcctta
    24781 tcaccccagc tcacttcgtt agtcatgtcc agctgaccaa ccgatgtaac cttaccactg
    24841 ctgagttcta aaatatagcc ctggatatca tacttgctgc tggcactgcc ctccgtaaaa
    24901 aacacatgac gttgatccgg tgataccaca gcaagtaact gtagagcgtt acgacctggt
    24961 gttaaaactc gctccttgtt ggtctttaca ttatgaatcc ataactgatt ctgacgttcc
    25021 acaatcagct cttcatcact cagccatgac ctcgcgtaga catctcccag cctgtcgatg
    25081 gattgtacca ccagttcgtc cgatacttgc tgccgagctg cacccatgtc aatcacagta
    25141 agcttttgcc ccggtttcat accggatgtt ggaattgtct ctcctgcgct ttttatgccg
    25201 cagccgctga gcaatcctcc agcgatcaag ccagtcatga gcaagcctgt gactttgtgt
    25261 ctgaaaaagc gtgcataggg atatttgaga cgaggaaagc cgttcttttg cccgtagttg
    25321 tctaggtttt gcttcatcat gtataccggc ctccttgtta acgttacccc cagcttaatg
    25381 cctgaacatc tcgtgaatac atcgaattgt ttccaaattg taaataagac aacattttca
    25441 gttctatagc tatctactga gagccatcgt gaaccaacag ggggagcctg agcgaaaatt
    25501 cattgccact tgcaactgaa tgaccattgc tattttccaa cccagtaccg cccgaagctg
    25561 taagctgcaa ctctccaccc atgcgctccg ccagtctgcg tgccagaggc aggccaagtc
    25621 ccgtaccact gtcctggcga gaacgatcac ggcttaaggt aacaaacggc tcaaaaatca
    25681 tgtcccattc ttccctagga atccatggac cggaattgca tatatacact atcacggtgt
    25741 ccttttccac tcgattggat aacgtgatcc agcctttgtc ctgattatat tttactgcat
    25801 tatccagcaa attcagtaca atatgcatta gatgcttagg atctccacac accttggctg
    25861 gaatggtatc catcgaaaaa tttagtccac gcgccgcagc tttcccccgg attcggctac
    25921 ctgcatcttc gagcagcaaa tgcagctcca cttcctccgt atgtaattca aaatcgtatt
    25981 tgtccagcac agatagtctc agtgaatcct cgacaagctc atacaaccgt tttgtttcct
    26041 taccgatact ttctctggct tcacgcacca attcgggatc atccccatac atatccagca
    26101 aatcagcgta agcctgaata gaggtcaacg gagtcttcag ttcatgactg atattgccaa
    26161 taaaagtctt ctgctgctgc tccagctctc gcaaacgctg aactgcttct tccagccgaa
    26221 gcttttcatt ctcgagcgcg gtaatactag cccggatcac atgactcatc tggagcatcc
    26281 cttcatccag ccttcctagc tcgtcctgac gtcgcagcaa tcgagcttct ggatagtgcc
    26341 ctgccgagat ctgctcagaa acgcgagtca gtcgtccgat gtccctcgtc tggcggctga
    26401 catagcctaa gcccagaaca aagcttaaaa ccaacaccgc ccctcctgtc cataaaaaca
    26461 agcgggcaat cgcctggtat aactgctgct gcgcttctgt tgagctatga agctgtacca
    26521 ctcccagcaa gccgtccgga ccttgcagcg gagccaaata agtaactgag ctaccttccg
    26581 taatatacgc aattttccct tggagcgcat aagaaagcgc ctggccgacg tttgttctat
    26641 aagccagtgg tagagaattt ccgacctcat ctccccggcc atcatataaa ataacgcgca
    26701 tattactgga tacgccaaac tccacggcaa gctgcggcgc ttgctttttc atgaagtctt
    26761 cgggcgattg gtgaactccc aacaggtaag actgttttac gcgcatctcc acgatttccg
    26821 cctgacgctt taagccgcgt tccatttggt ctgtctgatt agcacgaata ccggtaagta
    26881 cgagccagct cagcacaccg acagtaaaca gcagtaaagc cgccaggacc agcggaaatt
    26941 tccagcgcag gctcaagcct gtacgcttac gtttgcgctt tggctggtca gtggactgca
    27001 agcttccttc
//
