LOCUS       NZ_VANP01000016        21068 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold16, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000016
VERSION     NZ_VANP01000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 167868)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 167868)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 59321
            Orig. end                         :: 80389
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(839..2140)
                     /locus_tag="FED44_RS30220"
                     /old_locus_tag="FED44_30220"
     CDS             complement(839..2140)
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630797.1"
                     /locus_tag="FED44_RS30220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30220"
                     /product="dihydroorotase"
                     /protein_id="WP_117408565.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.6e-17, bitscore:
                     55.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTILIRGARILGGAPRDILLRDGVVAEIGDLAGAEAGQTIDAAG
                     LVALPGLVDLHTHLREPGREDAETVETGTQAAARGGYTAVHAMANTSPVADTAGVVEQV
                     WRLGQESGHCDVQPVGAVTSGLEGRQLAELGAMADSAARVRVFSDDGKCVSDAVLMRRA
                     LEYVKAFDGVVAQHAQEPRLTEGAQLNEGEVSARLGLTGWPAVAEEAIIARDCLLAAHV
                     GSRLHVCHVSTAGSVEIIRWAKSKGWDVTAEVTPHHLLLTDSCAETSPLGPYNPIYKVN
                     PPLRTAEDVRALREALADGTIDCVATDHAPHPVEDKETEWAAAAMGMIGLETALPVVQE
                     AMVETGLLDWAGVADRMSARPARIGRLSGHGRPIEPGAPANVTLYDPSVRRPVDPTAMA
                     SKSRNTPYEGMTLPGRVVATFLRGRPTVLEGKLV"
     gene            complement(2167..3102)
                     /locus_tag="FED44_RS30225"
                     /old_locus_tag="FED44_30225"
     CDS             complement(2167..3102)
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131603.1"
                     /locus_tag="FED44_RS30225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30225"
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_117408564.1"
                     /transl_table=11
                     /translation="MKPHLLSTGDLTRDDALLILDTAEELARVSQRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADAVVI
                     RHSASGAPHRLANWVRGSVVNAGDGTHEHPTQALLDAFSIRRRLGRLDGLKISIVGDVL
                     HSRVARSNVLLLHTLGADVTLVAPPTLLPVAVESWPCQVSYDLDAVLPKSDVVMMLRVQ
                     LERMNAAYFPSAREYSRRYGLDRDRFARLHDDAIVMHPGPMNRGMEISAEVADSPRSTI
                     VEQVGNGVTVRMAVLYLLLGGSEPAIGGAE"
     gene            complement(3099..3656)
                     /gene="pyrR"
                     /locus_tag="FED44_RS30230"
                     /old_locus_tag="FED44_30230"
     CDS             complement(3099..3656)
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131602.1"
                     /locus_tag="FED44_RS30230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30230"
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_117408563.1"
                     /transl_table=11
                     /translation="MSDVQNQARAVLEGPDIHRALTRIAHEILERTRGAESVVLLGIPT
                     RGATLAQRIAGRIAQFEGIKVPVGAIDITMYRDDLRLRPARPLGRTELPPDGVDGRTVV
                     LVDDVLFSGRTVRAALDALNDVGRPRAVQLATLVDRGHRELPIRADYVGKNLPTSKSEK
                     VKVFLEETDGRDAVVLIKGDDR"
     misc_feature    3637..3646
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     gene            4060..4554
                     /locus_tag="FED44_RS30235"
                     /old_locus_tag="FED44_30235"
     CDS             4060..4554
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="FED44_RS30235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30235"
                     /product="transcriptional regulator"
                     /protein_id="WP_117408562.1"
                     /transl_table=11
                     /translation="MPSDYAKSLGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLAPAPKLVIDLERLSQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPVELTEEFINWGVLDAEARRAVES
                     F"
     gene            4672..5916
                     /locus_tag="FED44_RS30240"
                     /old_locus_tag="FED44_30240"
     CDS             4672..5916
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889503.1"
                     /locus_tag="FED44_RS30240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30240"
                     /product="arginine deiminase"
                     /protein_id="WP_117408561.1"
                     /transl_table=11
                     /translation="MTFFVGSEVGRLRQVLVDIPELALKRLTPGNKDGLLFDDVLWVHR
                     ALEEHREWCEVLTARGVTVHHLGDLLREAIEVPDARKHILDGSVDEHWFGPLTADAIRN
                     TLDALDGAALAPYLTGGITKREIMELGCDPGSVVFHALGMDDFVLPPLPNHLFARDTSC
                     WVYGGVSINAMRKKARRRETLNFEAVYRWHPMFAPGYGDPSGGGFDVWYDGTRMAPATI
                     EGGDVLVLGDGVVLVGMSERTQPQAVEMLATKLFRAGAATRIVALDLPKTRAFMHLDTV
                     MTNVDVGVFTKYAGLGMLPSYTVEPGDTDKELKVTDHPPEDMHRAIARALGLDDIKVLT
                     PTQDVHAAEREQWDDGCNVLALEPGVVVAYERNTTTNNHLRRHGIEVIPIRGSELGRGR
                     GGPRCMSCPLERDPV"
     gene            complement(5963..6400)
                     /locus_tag="FED44_RS30245"
                     /old_locus_tag="FED44_30245"
     CDS             complement(5963..6400)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131600.1"
                     /locus_tag="FED44_RS30245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30245"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_117408560.1"
                     /transl_table=11
                     /translation="MTEENGDQRTGPRLPQAVLARLADARACLADATVGPTPADRYVSA
                     HLAALRAAAGILAARPRPMDGRRRRLRSAWELLPEVEPKLADWAAYFAMSATKRAAVEA
                     GMVRAVTQNDADEIIAEADRFVGEVESILGLPGRPTLPMAG"
     misc_feature    complement(6666..6681)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    6667..6680
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     misc_feature    6707..6720
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.27"
                     /tool="antismash"
     gene            complement(6792..7676)
                     /locus_tag="FED44_RS30250"
                     /old_locus_tag="FED44_30250"
     CDS             complement(6792..7676)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889495.1"
                     /locus_tag="FED44_RS30250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30250"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_244302386.1"
                     /transl_table=11
                     /translation="MMRGRRRPAAAMLVAMGAVAFATAGVAGPARAGAAVPAGAVTYAT
                     TGLAGAAPVSGARTVAARVAGARGALPGRAGYPPFEAPGKTLRLGAKGAAVKALQARLK
                     ELGYVPGSADGRYGGATLTAVWAFQKVQGIKPTSTVAARTWRALENPRAPRVLVPRGKA
                     TRVEVDLTKQVMVLYRSGVPVLISHISSGSGVPYTEYAVWNGKRQVFSGSARTPTGDYK
                     TTWRARGWHRSYLGQLYNPIFFNGGIALHGALSVPLYPASHGCVRLPMNVAGILPGMLG
                     KGVPVHVRGAFRR"
     misc_feature    7744..7758
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            7801..8277
                     /locus_tag="FED44_RS30255"
                     /old_locus_tag="FED44_30255"
     CDS             7801..8277
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="FED44_RS30255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30255"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_138462823.1"
                     /transl_table=11
                     /translation="MPEKLHPNVARVEQALRERQVTGEVVVLDDAAPTAATAAAQLGCE
                     IGAIANSLIFDADGAPLLVLTSGAHRVNTDLIARLVGAAKVRRATPEFVREHTGQPIGG
                     VAPVGHPAPVRTLVDTWLGKHEVVWAAAGHPHSVFPTSFDELVRITGGTPAEVE"
     gene            8320..8892
                     /locus_tag="FED44_RS30260"
                     /old_locus_tag="FED44_30260"
     CDS             8320..8892
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131597.1"
                     /locus_tag="FED44_RS30260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30260"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_138462824.1"
                     /transl_table=11
                     /translation="MIRLRRVGPDTFRAVLDTVLEIYTDAMRPPSDQLAGRMAIMRNHA
                     GYPDFACVLAEDPQGPGIAGFAYGFHGGPGQWWHDVVRGGLQDRAGPVVADEWFGDALE
                     IAEIHVRPEYQGKGVGRRMIHALCEGRPERTAVLSTHDAPTVARHLYRDVGFADLMTRF
                     VFPGGYEEYVIAGVRLPLPGPAPLPKD"
     gene            complement(8909..9835)
                     /gene="metF"
                     /locus_tag="FED44_RS30265"
                     /old_locus_tag="FED44_30265"
     CDS             complement(8909..9835)
                     /EC_number="1.5.1.20"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889491.1"
                     /locus_tag="FED44_RS30265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30265"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_138462825.1"
                     /transl_table=11
                     /translation="MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWR
                     AIRELEALRPTFVSVTYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHL
                     VGRFADAGVRNILAVRGDPRGGDPMDEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFP
                     YKHPRSATVESDTRYFVQKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGVM
                     PVTQMSTIARSEQLSGAPFPPEVAERFAAVADDPVAVRRLGIEHAAEMCRTLLDEGAPG
                     IHFITFNRSSATREVFQALHGVPAVAG"
     misc_feature    complement(9902..9922)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.51"
                     /tool="antismash"
     gene            10001..11068
                     /locus_tag="FED44_RS30270"
                     /old_locus_tag="FED44_30270"
     CDS             10001..11068
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131595.1"
                     /locus_tag="FED44_RS30270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30270"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_111700303.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 5.5e-51, bitscore:
                     166.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSAASLDHIRTEVDRVLREFLDRQRPHFEDPQLAVLLSAAEDF
                     LAGGKRLRPAFCHWGWRAAGGGDEPGLHFAAASLELLQASALIHDDVMDASDVRRGMPS
                     AHRRFERLHADAGWHGSARQFGEGSAVLLGNLLLVWSGEMWRGSGLDPRAIAAAQPLHD
                     YMLTELMCGQYLDLLEQAQGESTFDSALRVALYKSGKYSVEQPLRLGLVLAAQARHSWI
                     DRLCVQYGQRVGIAFQLRDDILGVFGDPAETGKPAGDDLREGKRTVLIARALAGATPAQ
                     QDVVRTLLGDPGLDADGVARLRTVIEETGALTDCEDMIKRYLDEALHALEQAPIEEDAR
                     AALAALAVAATSRRT"
     gene            complement(11229..11879)
                     /gene="thiE"
                     /locus_tag="FED44_RS30275"
                     /old_locus_tag="FED44_30275"
     CDS             complement(11229..11879)
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131594.1"
                     /locus_tag="FED44_RS30275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30275"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_244302388.1"
                     /transl_table=11
                     /translation="MNDTRRRLAQARLYLCTDGRRDRGDLEDFLDAVLAGGVDIVQLRE
                     KGLEAREELDLLEVFRAACDRHGALLAVNDRADVAYAARPDILHLGQDDLPVSVAREIL
                     GPGVLVGRSTHSAAEASAAATEPGVDYFCCGPVWPTPTKPGRPAPGPALLEHAAGLGSD
                     RPWFGIGGIGPENLDEVMAHGVRRVVVVRAVTEAEDPGAAASALKARLSAVPL"
     gene            complement(11908..12285)
                     /locus_tag="FED44_RS30280"
                     /old_locus_tag="FED44_30280"
     CDS             complement(11908..12285)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131593.1"
                     /locus_tag="FED44_RS30280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30280"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_111700302.1"
                     /transl_table=11
                     /translation="MTLTVAQIDRETDQLVGEWLPLSQAAEKLGLSIGRTKQLLKDKKL
                     VGARRSGGGQPQIPSVFVAHGEVLKGLPGTLTVLADAGYDEVESIRWLFTPDDSLPGAP
                     IDAIVKGRHTEVKRRAQALGF"
     misc_feature    complement(12317..12334)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.43"
                     /tool="antismash"
     gene            complement(12329..13507)
                     /locus_tag="FED44_RS30285"
                     /old_locus_tag="FED44_30285"
     CDS             complement(12329..13507)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853358.1"
                     /locus_tag="FED44_RS30285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30285"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_138462826.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.5e-53, bitscore:
                     172.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHVVVVGAGLAGVRSIEALRSRGFTGRITLIGEEHHRPYDRPPL
                     SKAVLLGDADSTVVDSDLDAMDVRLCLGTAAKGLRNGVLETTEGELEYDGLVIATGAAP
                     IRLRGEGHQHVLRTIDDALALRELLVPGARVAVIGAGWIGAEVATAAARAGCAVTVVEA
                     GESPLAAAVGPAVGCHTIGWYARAGVELRLGAMVGTVDADGLTLMSGARVPADVVVTGV
                     GVRPSVEWLKGSAVRLDDGVVVDEHLRTSLPNVVAVGDCANWWSRRFGTRLRVEHWDTA
                     LQAPDTAAATLLGEEAVYDPVPYFWSEQFDHMLQFAGHPTPDDRVLLRGDPRADGKWAV
                     CWLTPEDRLAAVFTVDLPRDVVQGRRLVEGGRRLDPRRVADPAVPLRDCIMT"
     misc_feature    13600..13615
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     regulatory      13679..13790
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     gene            13779..14915
                     /gene="thiO"
                     /locus_tag="FED44_RS30290"
                     /old_locus_tag="FED44_30290"
     CDS             13779..14915
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573834.1"
                     /locus_tag="FED44_RS30290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30290"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_244302390.1"
                     /sec_met_domain="DAO (E-value: 3.2e-72, bitscore: 237.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTRPSGIEPGHDVVIVGGGVAGLAVAWRTARRGLSVAVVDPVP
                     GGGATHAAAGMLAPVSEVTYTEEPLLRLGLASLAAWPAFRAELEDESGAELDYRTEGTL
                     EVARGADDMAFLDDLAAFERTLGLRVERLTGRECRSFEPMLSPSVRGGLLARDDAWVNP
                     RRVVRALLTAFEKAGGTLVAERAAGIVLPGRGSPSVRLESGGTVPAGRVVVAAGSWSAS
                     LLPGLPVRPVKGQILRLRGPRGFLTRCVRGLVHGSPAYLVPRGDGEITLGATSEELGYD
                     ARVTAGGVYELLRDARELVPGLTELELAETAVGFRPGTPDNLPLIGPAGHPGVLAATGH
                     GRNGVLLAPITAEAVAALLTGGAVPEAALSCDPGRFRE"
     gene            14912..15112
                     /gene="thiS"
                     /locus_tag="FED44_RS30295"
                     /old_locus_tag="FED44_30295"
     CDS             14912..15112
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131590.1"
                     /locus_tag="FED44_RS30295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30295"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_138462827.1"
                     /transl_table=11
                     /translation="MKVTINGDPAELPEGATVGDAVRILTALTSGVAVAVNGEVVSRSA
                     WESTRVEDGDGVEVLTAVQGG"
     gene            15118..15897
                     /locus_tag="FED44_RS30300"
                     /old_locus_tag="FED44_30300"
     CDS             15118..15897
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017617057.1"
                     /locus_tag="FED44_RS30300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30300"
                     /product="thiazole synthase"
                     /protein_id="WP_167521632.1"
                     /transl_table=11
                     /translation="MTEQDASGDVFVLGGEKFASRLIMGTGGAPSLEVLDQALEASGTE
                     LTTVAMRRLDPAARGSVLDLLRARNIKVLPNTAGCFTAGEAVLTARLAREALETNWVKL
                     EVIADERTLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLEDAGCAAVMPLGAPI
                     GSGLGIRNPHSIELIAEAATVPVILDAGIGTASDAALAMELGCDAVLLASAVTRAHRPG
                     LMAAAMRQAVTAGRLARLAGRIPRRRYAEASSPSRPA"
     misc_feature    complement(15945..15959)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.78"
                     /tool="antismash"
     gene            16053..18059
                     /gene="pknB"
                     /locus_tag="FED44_RS30305"
                     /old_locus_tag="FED44_30305"
     CDS             16053..18059
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131588.1"
                     /locus_tag="FED44_RS30305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30305"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_138462829.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-54, bitscore:
                     178.2, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.2e-08, bitscore: 28.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLTDPLVGQLLDGRYRVESRIARGGMASVYLALDVRLDRTVA
                     VKVMHRSLAEDPQFVQRFIGEAKSVASLSHPNIVQVFDQGTDGANVYLSMEYVPGRTLR
                     DILRRRGRLPAREALEMVIPVLAALGAAHQAGLIHRDVKPENVLLADDGRVKVVDFGLA
                     RAIEATNQTKTGMMIGTIGYMSPEQVTTGLADARSDVYAAGIMLFELLTGRQPYAGETP
                     MSIAYRHVHETVPAPSSVVPGIPPQIDALVTAATDKDPARRPADATAMLVAAVEIHRTL
                     PKTGHTGGHARPGVAGDSATGSTTGAHSMAGTGAHRAPAAPAGATPASGTAGHAQLGHT
                     MIQPRTDLLTGVMTGPAEAGGRRGTRRVRPVWFLAALALVMLAGVAFTGWWFSEGRYTK
                     VPDLVNKPLTVARQEAQNHGFEVQVLKPVFDDKIPKDVVLNTEPGPGAEVVKGAVLKLV
                     PSAGPETIPVPKVEGLSLADARAKIAEAGLTPGRVSRSASETIPRDQVIRTNPLVGKRV
                     RKGGSVNFVVSAGLLMPDVTQMMRDQAEKFLRDKGFNVQIDETADDAPPGTVIAQDPSG
                     GAEVVAGATVHLTVSRGPDQGFHWPWETDPSQAAPDFVNVPDVRFKAVRDAVSELKAAG
                     FKVRVRELVGTQRVVGENPLGQQPQGSTITIWH"
     gene            complement(18205..18792)
                     /locus_tag="FED44_RS30310"
                     /old_locus_tag="FED44_30310"
     CDS             complement(18205..18792)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014045.4"
                     /locus_tag="FED44_RS30310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30310"
                     /product="NYN domain-containing protein"
                     /protein_id="WP_165900627.1"
                     /transl_table=11
                     /translation="MAERVAVFLDFQNVHLSGHGLFESYGLPLYRCVPDPAGVADLIGQ
                     RRSRASEVTAVRVYRGRPDPNFQPLPAAANDAQTARWTHDRRVQVIRRQLNYRGWTDGM
                     PPQEKGIDVALAVDLIHLALRGQYDALVLFSSDTDLLPAVETIKGLRLGHIEVACWSGF
                     KPLRIKGTNLPYCHFLNKDDWAAVIEDWTDRI"
     misc_feature    complement(18583..18585)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18960..19949)
                     /gene="alc"
                     /locus_tag="FED44_RS30315"
                     /old_locus_tag="FED44_30315"
     CDS             complement(18960..19949)
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541667.1"
                     /locus_tag="FED44_RS30315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_30315"
                     /product="allantoicase"
                     /protein_id="WP_138462830.1"
                     /transl_table=11
                     /translation="MNAFTRLPDLALRTYGGSVVAANDESFAEREALIRPGPAEFRPHT
                     FGAKGQVYDGWETRRRREAGHDWAIVRLGMPGVVRGVVVDTAWFRGNYPPYASVEACAA
                     EGHPAPEELDGWVEIVPKSPLRGDATHEFAVTDPRRFTHVRLNIFPDGGVARLRVHGRV
                     VPDPAFLHGLTVDLAALENGGFVTACSDEFYSSPNNVLAPGLARNQAEGWETARRRDGG
                     NDWLVVALAGPGRIAVAEIDTANLKFNAPGWASLTGIDTGRAPQPDDGQAPPPDDDAWF
                     PLLPKTRLQPDTRHRFRLDDDRRVTHVRLDIFPDGGLARLRLPGTLIA"
ORIGIN
        1 tgcaccggct ggttcacgcc gcggtggccg taccgcagct tgtaggtgcc gaggccgagc
       61 gcccggccga ggatctggtt gccgaagcag atgccgaaga acggcacgct cgcgtccagc
      121 acctcacgca gcgactcgac cgcgtacccg gccgcggcgg ggtcgccggg gccgttggag
      181 aagaagacgc cgtcggggcc gagggcgagg atgtcggcgg cgccggcggt ggcgggaagc
      241 acgtgcacct cgcagccccg ctcggccatc cgctccgggg tcatcgcctt gatgccgagg
      301 tcgaccgcgg cgacggtgaa gcgcttgcgc ccgcgcgccg gcacgacgta cggctcgggc
      361 gtgcttacct cgcgggcgag gtcggcgccc tccatgccgg gcgagcgccg cacgcgctcg
      421 accagctcgg cgacgtcgcc gccctcgctg aagacaccgg cgcgcatcgc gccgcgctcg
      481 cgcaggtggc gggtgagggc ccgggtgccg gacatggcga tgccgacgac gccctgctcg
      541 cgcaggtact cgtcgagcgt ccggcgggag cgccagttcg acgggatccg cgacggctcg
      601 cgcaccacgt agcccgcgac ccagacgcgg cgggactcgg ggtcctcatc gttcacgccg
      661 gtgttgccga tgtggggggc ggtcatcgcc acgatctggc ggtggtagga ggggtcggtg
      721 agggtctcct ggtagccggt catgccggtg ttgaagacca tctcgccgaa cgtctcgccc
      781 acggcgccgt acggcgttcc ctcgaagacg cgtccgtcct cgagaaccag cagggctgtc
      841 atacgagctt cccttcgaga acggtggggc ggccgcgcag gaacgtggcg accacgcggc
      901 cgggcagggt catcccctcg tacggggtgt tccggctctt cgacgccatc gcggtggggt
      961 cgacgggccg ccggaccgac gggtcgtaca gggtgacgtt ggcgggcgcg ccgggctcga
     1021 tgggccggcc gtgcccggac aggcggccga tcctggccgg ccgcgcggac atgcggtcgg
     1081 cgacgccggc ccagtcgagc agcccggtct cgaccatggc ctcctggacc accggcaggg
     1141 ccgtctccag gccgatcatg cccatcgccg ccgcggccca ctcggtctcc ttgtcctcga
     1201 ccgggtgggg ggcgtggtcg gtggccacgc agtcgatcgt gccgtcggcg agggcctcgc
     1261 gcagcgcgcg cacgtcctcg gcggtgcgca gcggcgggtt caccttgtag atcgggttgt
     1321 acggcccgag cggcgaggtc tccgcgcagg agtcggtcag cagcaggtgg tgcggggtga
     1381 cctcggcggt cacgtcccag cccttcgact tggcccaccg gatgatctcg acggagcccg
     1441 cggtggagac gtgacagacg tgcagccggg agccgacgtg cgcggcgagc aggcagtcgc
     1501 gggcgatgat cgcctcctcg gcgacggccg gccagccggt caggccgagc ctggccgaca
     1561 cctccccctc gttgagctgg gcgccctcgg tcagccgggg ctcctgggcg tgctgggcga
     1621 ccacgccgtc gaacgccttg acgtactcca gcgcccggcg catcagcacc gcgtccgaga
     1681 cgcacttccc gtcgtcggag aagacccgga cgcgggccgc ggagtcggcc atcgcgccga
     1741 gttcggcgag ctggcggccc tccaggccgg aggtcaccgc gccgacgggc tggacgtcgc
     1801 agtggccgga ctcctggccg agccgccaga cctgctcgac caccccggcg gtgtcggcca
     1861 ccggggaggt gttggccatc gcgtggacgg cggtgtatcc gccgcgcgcc gcggcctggg
     1921 tgccggtctc gacggtctcg gcgtcctccc ggcccggctc gcgcagatgg gtgtgcaggt
     1981 cgacgaggcc gggcagggcg accagcccgg cggcgtcgat cgtctggcct gcctcggcgc
     2041 ccgcgaggtc gccgatctcg gccacgacgc cgtcgcgcag caggatgtcg cgcggggcgc
     2101 cgcccaggat gcgggcgccc ctgatgagga tggtggtcac agctccctcg tgaaggtcgt
     2161 acgcgttcat tcggcgcctc cgatggcggg ctcggaaccg ccgagcagca ggtagaggac
     2221 ggccatccgg acggtgacgc cgttgccgac ctgctcgacg atcgtcgagc gcggcgagtc
     2281 ggcgacctcc gcggagatct ccatgccgcg gttcatcggc ccggggtgca tgacgatcgc
     2341 gtcgtcgtgc aggcgggcga agcggtcgcg gtcgaggccg tagcggcggc tgtactcccg
     2401 cgccgagggg aagtaggccg cgttcatgcg ttcgagctgg acccgcagca tcatcacgac
     2461 gtccgacttc ggcagcacgg cgtcgaggtc gtacgagacc tggcagggcc agctctccac
     2521 cgccaccggc agcagggtgg gcggcgcgac gagcgtgacg tccgcgccga gcgtgtgcag
     2581 cagcagcacg ttcgaccggg cgacccggct gtgcagcacg tcgccgacga tcgagatctt
     2641 cagtccgtcg agccggccga gcctgcggcg gatgctgaac gcgtcgagca gcgcctgcgt
     2701 cgggtgctcg tgggtgccgt cgccggcgtt caccacgctg ccgcgcaccc agttggccag
     2761 gcggtgcggc gcgcccgagg cgctgtgccg gatcaccacg gcgtcggcgc ccatggcctc
     2821 cagggtgagc gcggtgtcct tcagcgactc gcccttggac acgctcgacc ccttggccga
     2881 gaaattgatc acatcggccg acaggcgctt ggccgcggcc tcgaaggaga tgcgggtccg
     2941 ggtggagtcc tcgaagaaga ggttcaccac cgtccggccg cgcagcgtcg gcagtttctt
     3001 gatcgaccgc tgcgagaccc gggcgagctc ctccgccgtg tcgaggatga ggagggcgtc
     3061 gtcgcgggtg aggtcgccgg tcgagagcag gtgcggcttc atcggtcgtc ccccttgatg
     3121 agcacgaccg cgtcgcgccc gtccgtctcc tccaggaaga ccttgacctt ctcgcttttg
     3181 gaggtcggca ggttcttgcc gacgtagtcg gcgcggatcg gcagctcccg gtggccgcgg
     3241 tccaccagcg tggcgagctg gaccgcccgg ggcctgccca cgtcgttcag cgcgtcgagc
     3301 gcggcgcgca ccgtacgccc ggagaagagc acgtcgtcca cgaggacgac ggtcctgccg
     3361 tccacgccgt ccgggggaag ctcggtgcgg ccgagcgggc gcgccggacg caggcgtagg
     3421 tcgtcgcggt acatcgtgat gtcgatcgcg ccgacgggga ccttgatccc ctcgaactgc
     3481 gcgatccggc cggcgatccg ctgggccagg gtggcaccgc gggtggggat gccgagcagg
     3541 acgacgctct cggcgcctct cgtccgttcc aggatctcgt gcgcgatccg cgtgagcgcc
     3601 cggtggatgt cgggcccctc caggacggca cgggcctgat tttggacatc ggacatgaaa
     3661 aagtcaccac ctttcccgcc tcacgggacg ggtcttaaaa gggtgtcagg tctgcttaga
     3721 gtatcagggc cctccgccat cccccctccc gccaggggtg atacgccggg gaggcggcgt
     3781 ccgccccgga tccccggagg atcggaagcc gcatcacatc gggtgtcggg gatttcggtg
     3841 agagcactgt ttggcgctct tttttccaat cagcttgacc tttgggagtg tcggctttac
     3901 cgtcactgtc cgtaaccaca acacgcgacc ttcctgggta aaacccgacg cagcggtcac
     3961 cgaaggtgcc ggggccggtg ccagccccgg tgttcggaac gcttgggaca aggacgcaca
     4021 atcaagtgag aagagacata gaaagccggg ggccacacga tgccgtctga ctacgccaag
     4081 tcgctgggcg cgcgcctgcg cgccatccgg acccagcagg ggctgtccct gcacggtgtc
     4141 gaggagaagt cccgtggccg gtggaaggcc gtcgtcgtgg gctcctacga gcggggcgac
     4201 cgcgcggtga ccgtgcagaa gctcgccgag ctcgcggact tctacggggt gccggtctcc
     4261 gagttgctgc cgggcggggc cgctcccagt ccgctcgccc cggctcccaa gctggtcatc
     4321 gacctggagc ggctgtcgca gctgccgaag gacaaggccg gtccgctggc ccgctacgcg
     4381 gccacgatcc agagccagcg tggtgactac aacggcaagg tgctgtccat ccggcaggag
     4441 gacctgcgct cgctggcggt catctacgac aagtcacccg tcgagctgac cgaggagttc
     4501 atcaactggg gcgtgctcga cgccgaggcc cgccgcgccg tcgagtcctt ctgaccactc
     4561 ctcccggccg ttccctccga ccaccgggcc gccgcggcgg ccccccatcg gcctccgcac
     4621 gccggggagc cgcgtcacga gtgattcctg tcataggggg ataggcagga catgactttt
     4681 ttcgtgggct cggaggtggg caggctccgc caggtcctgg tcgacatccc cgaactggcg
     4741 ctcaagcggc tcacccccgg caacaaggac ggcctgctct tcgacgacgt gctctgggtg
     4801 caccgcgcgc tggaggagca ccgggagtgg tgcgaggtgc tcacggcgcg cggcgtcacg
     4861 gtgcaccacc tcggcgacct cctgcgggag gcgatcgagg tgcccgacgc gcgcaagcac
     4921 atcctggacg gcagcgtcga cgagcactgg ttcggcccgc tgaccgccga cgcgatccgc
     4981 aacacgctgg acgccctcga cggagccgcg ctcgcgccgt acctgaccgg cgggatcacc
     5041 aagcgcgaga tcatggaact gggctgcgac ccggggtccg tcgtcttcca cgcgctcggc
     5101 atggacgact tcgtcctccc gccgctgccc aaccacctgt tcgcccgcga cacctcctgc
     5161 tgggtgtacg gcggggtgtc catcaacgcg atgcgcaaga aggcgcgcag gcgcgagacc
     5221 ctcaacttcg aggcggtcta ccggtggcac ccgatgttcg ccccgggcta cggcgacccg
     5281 tccggcgggg ggttcgacgt ctggtacgac ggcacccgca tggcccccgc caccatcgag
     5341 ggcggtgacg tgctggtgct cggcgacggc gtcgtgctcg tcgggatgag cgagcgcacc
     5401 cagccgcagg cggtcgagat gctggcgacc aagctcttcc gggcgggcgc ggcgacccgc
     5461 atcgtggcgc tcgacctccc caagacccgc gcgttcatgc acctcgacac cgtgatgacc
     5521 aacgtcgacg tgggggtgtt caccaagtac gccgggctcg gcatgctgcc gtcgtacacg
     5581 gtggagccgg gcgacaccga caaggaactg aaggtcaccg accatccgcc cgaggacatg
     5641 caccgagcga tcgcgcgggc cctcggcctg gacgacatca aggtcctcac gccgacgcag
     5701 gacgtgcacg cggccgagcg cgagcagtgg gacgacggct gcaacgtgct ggccctggag
     5761 ccgggagtcg tcgtcgccta cgagcgcaac accacgacca acaaccacct gcgcaggcac
     5821 ggcatcgagg tcatcccgat ccggggcagc gagctcggcc gcgggcgcgg cgggccccgc
     5881 tgcatgagct gccctctgga gcgcgatccc gtctgaggcc gcacccggcc gccggcggac
     5941 cctgggcgcc cttgcagcgc cgtcagccgg ccatggggag ggtggggcgg ccgggcaggc
     6001 cgaggatcga ctcgacctcg ccgacgaacc tgtccgcttc cgctatgatc tcgtctgcgt
     6061 cgttctgagt gacggcccgg accattccgg cctcgaccgc cgctcgcttg gtcgcgctca
     6121 tcgcgaagta ggccgcccag tccgcgagct tcggctcgac ctcggggagc agttcccagg
     6181 cgctgcgcag ccgccgcctg cgtccgtcca tcggacgggg acgcgcggcg aggatcccgg
     6241 cggccgcgcg cagcgccgcg agatgggccg acacgtagcg gtccgcgggc gtgggcccga
     6301 cggttgcgtc ggcgaggcac gccctggcgt ccgcgagacg cgccaggacc gcctgcggaa
     6361 gccggggccc ggtccgctga tcgccgttct cttcagtcat gcccgcctcc ttgagtcgtg
     6421 gcatccggcg aaggccgccg gtgacttcac agtcgcagac agcaccgaca atttcgatcg
     6481 gccgcgtaat cccgggcacc accgggatca cgcggctttc tcacgctccc gtgggcggcc
     6541 ggacgaggag cttcccctct ccccgtccgg cccacgccgc gggccgtgcc gcatccgtct
     6601 ccgccgacga cgtaggcacg gatccgacgg tgtgggcgca ggccgcgagt cccgcgccca
     6661 caccatcgaa catagattcg accattcccc ctgtcaagga tgtcaacgaa caagggttcg
     6721 aggactggca gggacccgta cgacgaaggg ccccgcgcga acacgtcgcg cggggccctc
     6781 gggtccgcgg gttatcgccg gaaagcacct ctgacgtgca cgggaactcc cttgccgagc
     6841 atgcccggaa ggatcccggc gacgttcatc ggcagccgta cacagccgtg cgacgccgga
     6901 tagagcggca ccgacagcgc gccgtggagg gcgatcccgc cgttgaagaa gatcgggttg
     6961 tagagctgcc ccaggtagga ccggtgccag cccctggccc gccatgtggt cttgtagtcg
     7021 ccggtcggcg tgcgggcgct gccggagaag acctgcctct tgccgttcca cacggcgtac
     7081 tcggtgtagg gaacgccgct gccgctggag atgtgactga tcagcaccgg gacgccggaa
     7141 cgatacagaa ccatcacctg tttggtcagg tccacctcga cccgggtggc ctttccgcgg
     7201 ggcacgagga cccggggcgc gcgggggttc tccagcgccc tccaggtgcg ggcggcgacc
     7261 gtgctggtcg gcttgatccc ctgcaccttc tggaacgccc agaccgccgt cagcgtggcc
     7321 ccgccgtacc ggccgtcggc gctgccgggc acgtagccga gctccttgag ccgggcctgc
     7381 agcgccttca cggcggcgcc cttcgccccg agcctgagcg tcttgcccgg cgcctcgaac
     7441 ggcgggtatc cggcccgtcc cggcagggct ccccgcgctc cggccacccg cgccgcgacc
     7501 gtccgcgcgc cggacaccgg cgccgcgccg gcgaggccgg tcgtcgcgta cgtcacggct
     7561 cccgccggaa cggcggcgcc ggcccgcgcc gggccggcga ccccggccgt cgcgaacgcc
     7621 acggccccca tcgcgacgag catggccgcg gccggtcgcc gtcgacctct catcatgacc
     7681 aacccctcat aagcctgatt cctaacaaag gactcacctt acggtccgat tgcgagccgt
     7741 gtgatcacaa gtggcgataa tcggccgcgt ctgtcctggc aatccgttta gagtggccgg
     7801 gtgccggaaa agttgcatcc gaacgtcgcc cgagtcgagc aggccctgcg ggagcggcag
     7861 gtgaccggtg aggtcgtcgt gctcgacgac gccgcgccga cggccgccac ggcggcggcc
     7921 cagctcggct gcgagatcgg cgcgatcgcc aacagcctga tcttcgacgc ggacggcgcg
     7981 ccgctgctgg tgctgaccag cggcgcccat cgcgtgaaca ccgacctgat cgcgcggctc
     8041 gtcggagcgg cgaaggtgcg cagggcgacg ccggagttcg tccgggagca caccgggcag
     8101 cccatcggcg gcgtggcccc ggtcgggcac ccggcgcccg tgcggacgct cgtggacacc
     8161 tggctgggca agcacgaggt cgtgtgggcc gccgccgggc atccgcactc ggtcttcccc
     8221 acctccttcg acgagctcgt acggatcacc gggggcaccc ccgccgaggt cgaatgacgt
     8281 ccgcggccgg cctggcggcg ctttgctagt gtgcgacgcg tgatccgact gcgccgggtg
     8341 gggcccgaca cgttcagggc ggtgctggac accgtgctgg agatctacac ggacgccatg
     8401 cggccgccgt cggaccagct cgcgggccgc atggcgatca tgcgcaacca cgccggttat
     8461 cccgacttcg cctgcgtcct cgccgaggac ccacagggcc ccggcatcgc cggcttcgcg
     8521 tacggcttcc acggcggccc cggccagtgg tggcacgacg tcgtccgcgg cggcctgcag
     8581 gaccgggcgg ggccggtggt ggccgacgag tggttcggcg acgccctgga gatcgccgag
     8641 atccacgtac gccccgagta ccagggcaag ggcgtcgggc ggcgcatgat ccacgcgctg
     8701 tgcgagggcc gcccggagcg aaccgccgtg ctgtccacgc acgacgcccc cacggtggcc
     8761 cgccatctct accgcgacgt gggcttcgcc gacctgatga cccggttcgt cttcccgggc
     8821 ggctacgagg agtacgtcat cgcgggggtg cggctgccgt tgcccggccc cgcgccgctc
     8881 ccgaaggact gatacgcggg cgggcgggtc agccggcgac ggcgggcacg ccgtgcagcg
     8941 cctggaacac ctcgcgggtc gcgctcgacc ggttgaaggt gatgaagtgg atgccggggg
     9001 cgccctcgtc gaggagcgtc cggcacatct cggcggcgtg ctcgatgccc aggcggcgga
     9061 ccgccaccgg atcgtcggcg acggccgcga accgctcggc cacctccggc gggaacggcg
     9121 cgccggacag ctgctcggac cgggcgatcg tgctcatctg cgtcacgggc atgacgcccg
     9181 ggatgatcgg cgtgtcgcac ccctgggccg ccacgcggtc gcgcagccgc aggtagtcct
     9241 ccgcgcggaa gaacatctgg gtgatcgcgt agtcggcgcc ggcccggcac ttctgcacga
     9301 agtatctcgt gtccgactcg accgtggccg acctcgggtg cttgtacggg aaggccgcca
     9361 cgcccacgca gaagtcgccc gcctggcgga tcagccgcac caggtcctcg gcgtacagga
     9421 cgccctcggg gtgcctgacc cattcgtcca tcgggtcgcc gccgcgcggg tcgccgcgta
     9481 cggcgaggat gttgcgcacc ccggcgtcgg cgaaccggcc gacgaggtgg cgcagctcac
     9541 ggatcgagtg gtcgacggcg gtgaagtggg cgacgggcgt cagcgtcgtc tcgtgggcca
     9601 gccgctcgac gatgtccacg gtgcggtcgc gggtcgagcc gccggcgccg taggtgacgg
     9661 agacgaacgt cggccgcagc gcctccagtt cgcggatcgc gcgccacagc tggcgctccc
     9721 cctcgtcggt cttcggcggg aagaactcga acgagaacga gcgctcgccc gcggccagca
     9781 gttcacggac cgtcgggacg cgatcgggaa gccgcgaggg cagaccgaga gccatacggg
     9841 aaagattaca gcgcgggccg gtccccggcc tcgcggtctt gccatgtgga ccggccgcat
     9901 gtactggtca tccggacgtt ttgccctaac agcgcgagct gaccaattta gaggggatct
     9961 gcgctgtgat gtcgggatct ggcccggtta ctctctgagc atgaccactt ccgccgcctc
    10021 gctcgaccac atccgtacgg aggtggaccg cgttctccgg gagttcctcg accggcaacg
    10081 cccacacttc gaggatccgc aactcgccgt cctgctgtcc gccgcggagg acttcctcgc
    10141 cgggggcaag cggctgcgtc ccgccttctg ccactggggg tggcgcgccg ccgggggcgg
    10201 cgacgagccg ggactgcact tcgccgccgc gtcactggag ctgctccagg ccagcgcgct
    10261 gatccacgac gacgtcatgg acgcgagcga cgtacgccgc ggcatgccct cggcgcaccg
    10321 gcgcttcgaa cgcctgcacg cggacgcggg ctggcacggg tcggcgcggc agttcggcga
    10381 gggctcggcc gtgctgctgg gcaacctgct gctggtgtgg tccggcgaga tgtggcgcgg
    10441 cagcggcctg gacccccggg cgatcgccgc cgcccagccc ctgcacgact acatgctcac
    10501 cgagctgatg tgcgggcagt acctcgacct gctggagcag gcgcagggcg agagcacctt
    10561 cgacagcgcg ctgcgggtgg ccctttacaa gagcggtaaa tattccgtcg agcagccgct
    10621 gcggctcggg ctggtcctcg ccgcccaggc ccggcactcc tggatcgacc gcctgtgcgt
    10681 gcagtacggc cagcgggtgg gcatcgcctt ccagctccgc gacgacatcc tcggcgtgtt
    10741 cggcgacccg gcagagaccg gcaagcccgc tggggacgac ctgcgcgagg gcaagcggac
    10801 cgtgctcatc gcgcgggcgc tcgccggggc cacccccgcc cagcaggacg tcgtacggac
    10861 cctgctgggc gaccccgggc tcgacgccga cggggtcgcg cggctgcgca cggtgatcga
    10921 ggagaccggt gcgctgacgg actgcgaaga catgatcaag cgttatctgg acgaggcgct
    10981 gcacgccctc gaacaggcgc cgatcgagga ggacgcccgc gccgcgctgg ccgccctggc
    11041 cgtcgccgcc acctcccgcc gcacctgacg acgcccctgc ccgggatcgc cggcacccga
    11101 gtcgccgtgc cgggcgattc cagatcggcg cgggcaaggc gaccgtggcc gggaccgcga
    11161 cgatcggccg cgtgcccggg cccggctccg ggcccgggcc gccgtggccg ttcaggcggc
    11221 gggccggctc acagcgggac ggccgacagg cgcgccttga gagccgaggc ggcggcgccg
    11281 gggtcctcgg cctcggtgac ggccctgacg accaccacac ggcgcacgcc gtgcgccatc
    11341 acctcgtcga ggttctccgg gccgatgccg ccgatgccga accacggccg gtcggagccc
    11401 aggcccgccg cgtgctccag caacgcgggg ccgggcgccg ggcggcccgg cttggtcggc
    11461 gtgggccaca ccggcccgca gcagaagtag tccacgcccg gttccgtcgc ggcggccgac
    11521 gcctcggccg ccgagtgggt cgacctgccg acgagcacgc cgggacccag gatctcccgg
    11581 gccacggaga ccgggaggtc gtcctggccg aggtgcagga tgtccggccg ggcggcgtac
    11641 gcgacgtccg cccggtcgtt caccgccagc agcgcgccgt gccggtcgca ggccgcgcgg
    11701 aacacctcca gcaggtccag ctcctcgcgg gcctccaggc ccttctcccg caactggacg
    11761 atgtccacgc cgccggccag gaccgcgtcg aggaagtcct ccaggtcgcc gcggtccctc
    11821 ctgccgtcgg tgcagaggta gagcctggcc tgcgcgagcc gtcgccgggt gtcgttcacc
    11881 cgaccaacaa tgccatgcgg cggacggtca gaagcccagc gcctgggccc tgcgcttgac
    11941 ctcggtgtgc cggcccttga cgatcgcgtc gatcggcgca cccggcaacg agtcgtccgg
    12001 ggtgaacagc cagcggatcg actccacctc gtcgtacccg gcgtcggcca ggacggtcag
    12061 cgtgccgggc aggcccttga gcacctcgcc gtgggcgacg aacaccgacg ggatctgcgg
    12121 ctggccgcct ccgctccgcc gggcgccgac gagcttcttg tccttcagga gttgcttggt
    12181 gcggccgatg ctgagcccca gcttctcggc cgcctgcgag agggggagcc actcccctac
    12241 gagctggtcg gtctcccggt cgatctgcgc aacagtaagc gtcacggaac caccattacc
    12301 acatgcgagc cgccgggaaa cacctcgatt acgtcataat gcagtcgcgg agcggcacgg
    12361 ccggatcggc cacccgccgg gggtcgagcc tccggccgcc ctccaccagg cggcggccct
    12421 gcaccacgtc gcgcggcagg tccacggtga acaccgcggc gagccggtcc tcgggggtca
    12481 gccagcacac cgcccacttc ccgtccgcgc gcgggtcgcc gcgcagcagc acccggtcgt
    12541 ccggggtcgg gtggccggcg aactgcagca tgtggtcgaa ctgctccgac cagaagtacg
    12601 gcacggggtc gtagaccgcc tcctcgccca gcagcgtggc ggcggccgtg tcgggggcct
    12661 ggagcgcggt gtcccagtgc tcgacccgca gccgcgtgcc gaacctgcgc gaccaccagt
    12721 tggcgcagtc gcccaccgcg accacgttcg gcagcgacgt gcgcaggtgc tcgtcgacga
    12781 ccacaccgtc gtcgagccgt acggccgagc ccttgagcca ttcgacggag gggcgcaccc
    12841 cgacgccggt gaccaccacg tcggcgggca cccgcgcgcc ggacatgagc gtgagcccgt
    12901 cggcgtccac cgtgccgacc atcgcgccga ggcgcagctc gacaccggcc cgggcgtacc
    12961 agccgatcgt gtggcagccg accgcgggac cgaccgcggc ggcgagcggg ctctcccccg
    13021 cctccaccac cgtcaccgcg caccccgccc gggccgccgc ggtcgcgacc tcggcgccga
    13081 tccagccggc gccgatgacg gccacgcggg cgccgggcac cagcagctcg cgcagcgcga
    13141 gcgcgtcgtc gatcgtgcgc agcacgtgct ggtggccctc tccccgcagc cggatcgggg
    13201 ccgcgccggt ggcgatgacc aggccgtcgt actccagctc gccctcggtc gtctccagca
    13261 cgccgttccg caggcccttg gcggccgtgc cgaggcacag ccgcacgtcc atggcgtcga
    13321 ggtcggagtc gaccacggtg gagtcggcgt cgccgagcag caccgccttc gacagcggcg
    13381 ggcggtcata ggggcgatgg tgttcctcgc cgatgagcgt gatgcgcccg gtgaaccccc
    13441 gggacctcag cgcctcgatg cttcgcacgc cggccaggcc ggcacccacc accacgacgt
    13501 gatccacgcc ttgaccatag attgtcaacg ggggaactgg ccaaccggct ccccataacg
    13561 agttgggcaa ggagcgcgca catctccggc agccccggtt gtgagccacg tcacgcccgc
    13621 ccgggtgagc gccgaaccgg gcgatccgcc ggtatcggcc acgtactacg ctgttgggcg
    13681 taagacgcgc gggagcccgg cggaccgggc tgagaggaga gcgtacggct ctcgaccgcc
    13741 caccacctga tccgggtaat gccggcgaag ggagcgcggt gtcctccaca cggccctccg
    13801 gaatcgagcc cggccacgac gtcgtgatcg tgggaggcgg cgtggcgggc ctcgccgtcg
    13861 cctggcgcac ggcgcggcgc ggactgtcgg tggcggtggt ggaccccgtg ccgggaggcg
    13921 gcgccaccca cgccgccgcc gggatgctcg cgccggtcag cgaggtgacc tacacggagg
    13981 agccgctgct gcggctcggg ctggcgtcgc tggccgcctg gccggcgttc cgggcggagc
    14041 tggaggacga gtccggcgcc gagctcgact accgcaccga gggcacgctg gaggtcgccc
    14101 gcggcgcgga cgacatggcc ttcctcgacg acctcgcggc cttcgagcgc acgctcggcc
    14161 tgcgggtgga acgcctgacc ggacgcgagt gccgctcctt cgagccgatg ctgtccccct
    14221 cggtgcgcgg cgggctgctg gcccgcgacg acgcctgggt caacccccgc agggtcgtgc
    14281 gcgcgctgct gaccgcgttc gagaaggcgg gcggcacgct ggtggccgag cgcgccgccg
    14341 ggatcgtcct tcccggccgg ggctccccgt cggtgcggct ggagtccggc gggaccgtcc
    14401 cggccggccg ggtcgtggtg gccgccggct cgtggtcggc ctccctgctc cccggcctgc
    14461 ccgtgcggcc ggtcaagggg cagatcctcc ggctccgggg cccccggggg ttcctcaccc
    14521 ggtgcgtacg ggggctggtg cacggttctc ccgcctacct cgtcccccgg ggcgacgggg
    14581 agatcacact gggcgccacc tccgaggagc tgggatacga cgcgcgggtc accgccggcg
    14641 gggtgtacga gctgctgcgc gacgcccgcg aactggtgcc cggcctcacc gagctcgaac
    14701 tggccgagac ggccgtcggg ttccgcccgg ggaccccgga caaccttccg ctcatcggcc
    14761 ccgccggcca ccccggcgtc ctcgcggcga ccgggcacgg ccggaacggc gtgctgctgg
    14821 ccccgatcac cgccgaggcc gtcgccgccc tcctcaccgg cggcgcggtg ccggaggccg
    14881 ccctgtcctg cgacccaggg agattccgcg aatgaaggtc acgatcaacg gagacccggc
    14941 cgagctgccg gagggggcga cggtgggcga cgccgtacgg atcctcacgg cgctcacgtc
    15001 cggcgtcgcg gtggcggtca acggcgaggt ggtgagccgc agcgcctggg aatccacccg
    15061 ggtggaggac ggcgacggcg tcgaggtgct cacggcggtg cagggaggat gacaggcatg
    15121 acggaacagg acgcgtccgg cgacgtcttc gtgctcggcg gggagaagtt cgcctcgcgc
    15181 ctgatcatgg ggaccggcgg cgcgccgtcg cttgaggtgc tcgaccaggc gctggaggcg
    15241 tccggcaccg agctgacgac cgtcgcgatg cgcaggctgg acccggccgc ccgcggctcg
    15301 gtgctcgacc tgctgcgggc gaggaacatc aaggtgctgc cgaacacggc cggctgcttc
    15361 acggccggcg aggccgtgct gaccgcccgg ctggcccgcg aggcgctgga gacgaactgg
    15421 gtcaagctgg aggtcatcgc cgacgagcgg accctgctgc ccgatccgat cgagaccttc
    15481 gacgcggcgg aacggctggt cgccgacggc ttcgtcgtgc tgccgtacat cggcgacgac
    15541 cccgcgctgg ctcggcggct ggaggacgcc gggtgcgcgg cggtgatgcc gctcggcgcc
    15601 ccgatcggct cgggcctcgg catccgcaac ccgcacagca tcgagctgat cgccgaggcg
    15661 gcgacggtgc cggtgatcct cgacgcgggg atcggcacgg ccagcgacgc ggcgctcgct
    15721 atggagctgg gctgcgacgc cgtgctgctc gccagcgccg tgacgcgggc gcaccggccc
    15781 ggcctcatgg ccgccgccat gcggcaggcg gtcacggccg gacggctcgc ccgcctggcc
    15841 gggcgcatcc cccgccgccg ttacgccgag gcgtcctccc cctctcgccc cgcctgaccg
    15901 caccggcccg gcgtccctcc ggttcggacg ccgggtaagg cgggttttag gatggagaac
    15961 ggctttccgg gtggcgcgga aagggccgcg tcaggtctcg gtttggggtt cgggaacacg
    16021 cccggcggca aatcacccgt aaactcgggc gggtggacac gacgctaacc gatccgctcg
    16081 tggggcagct gctcgacggg cgctaccgcg tcgagtcccg gatcgcccgg ggcggcatgg
    16141 cctccgtcta cctggctctg gacgtccggc tcgaccgcac ggtcgccgtc aaggtgatgc
    16201 accgttcact ggccgaggac ccgcagttcg tccagcggtt catcggcgag gccaagtcgg
    16261 tggcgagcct ctcgcacccg aacatcgtgc aggtcttcga ccagggcacc gacggggcga
    16321 acgtctacct gtcgatggag tacgtccccg gcaggacgct gcgcgacatc ctgcgccggc
    16381 gtggccgcct cccggcgcgc gaggccctgg agatggtcat cccggtgctc gccgccctcg
    16441 gcgcggccca ccaggcgggg ctgatccacc gggacgtcaa gcccgagaac gtgctgctcg
    16501 ccgacgacgg ccgggtgaag gtcgtggact tcggcctggc ccgggcgatc gaggccacca
    16561 accagaccaa gaccggcatg atgatcggca cgatcggcta catgtcgccg gagcaggtca
    16621 cgaccggcct cgccgacgcg cgcagcgacg tgtacgccgc cgggatcatg ctgttcgaac
    16681 tgctcaccgg gcgccagccg tacgccggtg agacgccgat gtcgatcgcc taccggcacg
    16741 tgcacgagac cgtgcccgcg ccgtcctcgg tcgtgcccgg catcccgccg cagatcgacg
    16801 cgctcgtcac cgcggccacc gacaaggatc ccgcccggcg cccggccgac gcgaccgcca
    16861 tgctggtcgc cgcggtcgag atccaccgca cgctgccgaa gaccgggcac accggcgggc
    16921 acgcccgccc cggcgtcgcg ggcgactccg cgacgggctc cacgacgggt gcgcacagca
    16981 tggccggcac gggggcgcac cgcgcgcccg ccgccccggc cggcgcgacc cccgcgtccg
    17041 gcacggccgg gcacgcgcag ctcggccaca cgatgatcca gccgcgcacg gacctgctga
    17101 ccggcgtcat gaccggcccg gcggaggcgg gagggcgccg cggcacccgc agggtcaggc
    17161 cggtctggtt cctcgccgcg ctggccctcg tcatgctcgc gggcgtcgcc ttcacgggct
    17221 ggtggttctc cgaggggcgc tacacgaagg tgcccgacct ggtgaacaag cccctcacgg
    17281 tcgcgcggca ggaggcgcag aaccacggtt tcgaggtcca ggtcctcaag ccggtgttcg
    17341 acgacaagat ccccaaggac gtcgtcctga acaccgagcc cgggccgggc gccgaggtgg
    17401 tcaagggagc ggtgctcaag ctggtcccgt cggccgggcc ggagaccatc ccggtgccga
    17461 aggtcgaggg cctcagcctc gcggacgccc gggccaagat cgccgaggcc gggctgacgc
    17521 ccgggcgggt cagccggagc gcgagcgaga ccatcccgcg cgaccaggtc atccgtacca
    17581 acccgctggt gggcaagcgc gtcaggaagg gcggctcggt caacttcgtg gtcagcgccg
    17641 ggctgctgat gccggacgtc acacagatga tgcgcgacca ggcggagaag ttcctgcggg
    17701 acaagggctt caacgtccag atcgacgaga cggccgacga cgccccgccg ggcaccgtga
    17761 tcgcgcagga cccctccggc ggcgcggagg tggtggccgg ggcgaccgtc cacctgaccg
    17821 tgtcacgcgg cccggaccag ggcttccact ggccgtggga gaccgacccc tcgcaggcgg
    17881 cgcccgactt cgtgaacgtg cccgacgtgc gcttcaaggc ggtgcgggac gcggtgtccg
    17941 agctgaaggc ggccgggttc aaggtcaggg tgcgcgaact cgtcggcacc cagcgcgtcg
    18001 tcggcgagaa ccccctcggc cagcaacccc agggcagcac catcacgatc tggcactgac
    18061 ccgccccgcc gcattcgtcg accatgtccg cacggatgcc atgcccctgg gaaaaatcgt
    18121 cacaggcggt tctcgttcag agaactgccg gtgagcccaa ggcatgaggc gcgaaagcgg
    18181 taccgccttg gacgtctcct ctgctcagat gcggtcggtc cagtcctcga tgaccgccgc
    18241 ccagtcgtcc ttgttcagga agtggcagta gggaagattg gtgcctttga tccggagagg
    18301 cttgaacccc gaccagcagg ccacctcgat gtgcccgagt cgcaacccct tgatcgtctc
    18361 cactgctggg agaaggtcgg tatcactcga gaacagcacc agagcgtcgt actgccctcg
    18421 cagcgcgaga tggatgagat cgacggccaa ggcgacgtcg atgcccttct cctgcggagg
    18481 cattccatcc gtccaaccgc ggtagttgag ttgtcgtcgg atcacctgga cgcggcggtc
    18541 gtgtgtccac cgggccgtct gcgcatcgtt ggccgctgcc ggtaacggct gaaagttggg
    18601 gtcgggacga cctcggtaga cccgcaccgc cgtcacctca ctcgcgcgcg acctccgctg
    18661 accgatcaga tcggcgaccc cggcgggatc gggcacgcat ctgtacagcg ggagaccgta
    18721 actctcgaag agaccgtgcc cgctcagatg gacgttctgg aagtccagga aaaccgcgac
    18781 acgttccgcc acgaggtcgt ctcccacatg aaaaagcccc gccagtcccg gaggacggcg
    18841 gggagtaatg gtcccagtgt agcagaacga gccgtactcg tttcgctacc ctccgaaatc
    18901 gccttgccac cctacttcgc gacatgctcg atacgcagcg attccatcgg ttcgggtgct
    18961 caggcgatga gggtgccggg gaggcggagg cgggcgaggc cgccgtcggg gaagatgtcg
    19021 aggcggacgt gggtgacgcg gcggtcgtcg tcgaggcgga agcggtggcg ggtgtccggc
    19081 tggagccggg tcttcggcag cagcgggaac caggcgtcgt cgtccggcgg gggcgcctgg
    19141 ccgtcgtccg gctggggcgc ccggccggtg tcgatgcccg tcagggaggc ccagccgggg
    19201 gcgttgaact tcaggttggc ggtgtcgatc tcggccacgg cgatccggcc gggcccggcc
    19261 agggcgacga cgagccagtc gttgccgccg tcgcgccgcc gggcggtctc ccagccctcg
    19321 gcctggttgc gggcgaggcc gggcgcgagg acgttgttcg gcgaggagta gaactcgtcg
    19381 gagcacgccg tgacgaaccc gccgttctcc agcgccgcga gatcgacggt cagcccgtgc
    19441 aggaacgcgg gatcgggcac tacccggccg tgcacccgca gccgcgcgac cccgccgtcg
    19501 gggaagatgt tcagccggac gtgcgtgaac cgccggggat cggtgaccgc gaactcgtgg
    19561 gtcgcgtcgc ccctgagcgg gctcttcggc acgatctcca cccagccgtc cagctcctcc
    19621 ggcgccggat gaccctcggc cgcgcacgcc tccaccgagg cgtacggcgg gtagttgccg
    19681 cggaaccacg ccgtgtcgac gacgacgccc cggacgaccc ccggcatgcc gaggcggacg
    19741 atcgcccagt cgtggcccgc ctcgcgccgc cggcgcgttt cccagccgtc gtagacctga
    19801 cccttggcgc cgaaggtgtg cggccggaac tcggccggtc cgggcctgat gagggcctcc
    19861 cgctcggcga acgactcgtc gttggccgcc acgaccgacc cgccgtacgt gcggagggcg
    19921 aggtcgggca ggcgggtgaa ggcgttcacc gcgctcctct ggtcagcaga cgtccggccg
    19981 gggtggcgag gtcggcgggc ctgccgcgca gccaggtggt gcggacgacg ccggacagcc
    20041 gccgcccgtc atagggcgag acggggttgc ggtggtgcag cgccgccacg tcgaccgtga
    20101 actcggcgtc ggggtcgaag gccaccaggt ccgcgtcgtt gcccggcctg atcgccccct
    20161 tgtacggcag gcccgcgagg cgggcggggc cctcggccat ccagcggacg acgtcggtaa
    20221 ggccgtaccc tctggcgcgg gcggcggtcc acacggcggg caggccgacc tggagcgagg
    20281 agatcccgcc ccaggccttg gcgaagtcgg gcaccttgag gtcgggcgtc gacggggagt
    20341 ggtcggagac gatccccatg agcaccccct cggcgagcgc ctcccacaac gcgtcgcggt
    20401 tggccgcctc ccggatcggc gggcagcact tgtacgccgg gccggtgacc tgctcggccg
    20461 ccagggtcag gtagtgcggg caggtctcgg cgctgacgcg caccccggcc gcccgcgcct
    20521 cgcgcagcgg ccggaggcag gcggcggccg acacgtgcac gatgtgcgcc ctggcgcccg
    20581 tctcggcggc cagcgcgatc acccgctcca ccgcccgccg ctcggcctcc tgcgggcgcg
    20641 acctgaggaa gtcgtcgtac gccgggccgc ccggctcgga cagcagcgcc gggtcctcgg
    20701 cgtgcgcgat cagcaggccg ccgaagcccg ccacctccgc gagcgcggcc cgcagcccgt
    20761 cgtggtcgag ctcggggaac tcctcgaccc cggacgggga caggaagcac ttgacgccca
    20821 tgacgccggc ctcgtgcagg gggcgcaggt cggggaggtt ccccgggacc gcgccgcccc
    20881 agaagccgac gtccacgtgg caccgcccct cggcggcctt ccgcttgacc tccagcgagg
    20941 cgacgtccag ggtcggcggc agcgagttca gcggcatgtc cacgatggtg gtgacgcccc
    21001 cggccgccgc cgccgcggtg gcggtcgcga agccctccca gtgggtgcgg ccgggctcgt
    21061 tgacgtgc
//
