LOCUS       NZ_VANP01000010        22157 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold10, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000010
VERSION     NZ_VANP01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 318508)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 318508)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 296351
            Orig. end                         :: 318508
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22157
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="PKS-like"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="(t2pks2 or ksIII)"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..22157
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="PKS-like"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..22157
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21011](+)"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21011
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="1"
     gene            complement(15..1487)
                     /locus_tag="FED44_RS25350"
                     /old_locus_tag="FED44_25350"
     CDS             complement(15..1487)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014909132.1"
                     /locus_tag="FED44_RS25350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25350"
                     /product="ATP-binding protein"
                     /protein_id="WP_111699818.1"
                     /transl_table=11
                     /translation="MDKPAEMFDRDYEWSALRRFITDEQPGATLGVVSGRRRQGKTFLL
                     DAACRAAGGFYFAATEAANAESLRRLSAALTAHVRPAVPYHFADWSEALDALLALGAER
                     PIPVVIDEFPYLARANPELPSLLQEAFRPMRDQRTRSRTRLLLCGSALSFMGRLLSGNA
                     PLRGRAGLEMLVRPLDHRLAAEFWEISDPALALKVNAVVGGTPAYRREFARGDTPSGPE
                     DFDDWVIRTVLNPETPLFREARYLLAEEPDLRDSALYLSVLAAVADGNATRGGVAGYLE
                     RRATDIAHPINVLEDAGLLHRDADAFRDNRATYRISEPLIRFYHAIMRPVWDQLERPGS
                     AGRVWQASRRRFVSNVLGPHFEQICRDWALHHADPDLFGGLPARVGHGVVHDPKARTGH
                     EVDVAVVGIADGGKAPLLAIGEAKWNDTMGAAHIERLRHLRDLIARTGRYDTTDTRLLC
                     FSGTGFNDKARAATAASPDVHLVDLPALYGRS"
     cand_cluster    1145..22157
                     /SMILES=""
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1145..22157
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[21144:>22153](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(21145..>22153)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="2"
     misc_feature    1511..1524
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.64"
                     /tool="antismash"
     gene            complement(1554..1676)
                     /locus_tag="FED44_RS38205"
     CDS             complement(1554..1676)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS38205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_262367350.1"
                     /transl_table=11
                     /translation="MRRPKAVTATTTTTRITAKRRRPRPADLDLRTPSGRVLPY"
     gene            complement(1673..2176)
                     /locus_tag="FED44_RS25355"
                     /old_locus_tag="FED44_25355"
     CDS             complement(1673..2176)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018984.4"
                     /locus_tag="FED44_RS25355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25355"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_111699817.1"
                     /transl_table=11
                     /translation="MSYREPLEETRLLESFANTIDVERGADLLESVEGMRAWLAAQGLP
                     AHVTPHDLARARTLRQGLRARLLADGEQPDRRSMAAAHAVLDGLALRSDDPLAAIARAW
                     LATTAGGEWPRLKRCPDRRCGWVFWDGSRDGTRTRCSRPPAASPGASPGPSGSAVLTVL
                     RGRP"
     gene            complement(2186..3631)
                     /locus_tag="FED44_RS25360"
                     /old_locus_tag="FED44_25360"
     CDS             complement(2186..3631)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="FED44_RS25360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25360"
                     /product="MFS transporter"
                     /protein_id="WP_138462278.1"
                     /transl_table=11
                     /translation="MLTHPSTRTVPDGIRGKSLIALSVVVAFWALIMVDEMVISISLAG
                     IGQALEMSQTQLSWVVNAYLLPYGGLLLLGGRAGDILGKRRVFVAGVAFYTAGCLVRAI
                     APDAWLVIAARGAQGVGAALATPCVLALIVSMFEEGPLRRRAISAYTIAGGAGAAVGLM
                     LVGLLGTISSWRVVLLPSAVFGLVLLVLGPMVIEETPRRPGRFDFAGALSATLGVVAIV
                     YGLTTSQGGDWLNGWVIGSVVAGLVLLALFVLISRRARQPLLDLGLFTDRSRVGAYLVL
                     MITPGAQIGLFFYLSQYFQIVLGYSTLTTAFAFLAVSVGMTGAASLAVRLEPRIGGRMV
                     VLIGAVLLLISNAWLLRMDIGDGYWTGVLPSLVLVGAGVAMAIIPAFSRATSGVESEDA
                     GAASSVVSMVQNVGSSLALAVIVVIATAASTRATEHPPAGLSKAALDGYVFSQGMQATF
                     LTGAGFAVAALLAALLIGRSRTS"
     gene            complement(3689..5299)
                     /locus_tag="FED44_RS25365"
                     /old_locus_tag="FED44_25365"
     CDS             complement(3689..5299)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="FED44_RS25365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25365"
                     /product="FAD-binding protein"
                     /protein_id="WP_111699815.1"
                     /transl_table=11
                     /translation="MTVYNRRGFLAGAAAAGAGLASGVALGGTPASAGTTGVRCVPEFG
                     PFVVRPGDPRFDSMRSGHNMRFTGAPDQVTVVGSAAQVVDAVGAAVAAGKRLVARSGGH
                     CMEDFTTTSDIKAVIDLSQMTAVYHDARRGAFAVEPGALVGEVAETLFKGWGVMIPFTG
                     CATVGIGGHIPGGGYGFFSRKHGLSVDHLNAVEVVTVDASGTPRVIVATDSPSDPNRDL
                     FWAHTGGGAGNFGIVTRYWFRTPGVTSNDPTRLLPRIGNQRARLLMWSWDAMTEQAFTT
                     LVGNYCTWYQNNSAPGSPAVNLWGTLTTNHRSAGTLMLLAGVDESVSGGQALLDAHFAA
                     VTSGVGVEPMVDVQETTPWLDPRNWVSDPAGRQKNKTADLRRSYTPAQIATLYRHLSDD
                     SYYNPNALVNITGFGGRINSVASGATAAVHRDSVLRVYFTAGGWSSSYEDEANMAWIRN
                     LYRELYQDTGGVPVPNAVNGGAFINYPDRDLADPAWNTSGTPWHALYYRDNYPRLQRIK
                     RQYDPRNVFRHGLSIGLPS"
     misc_feature    5309..5323
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            complement(5410..6084)
                     /locus_tag="FED44_RS25370"
                     /old_locus_tag="FED44_25370"
     CDS             complement(5410..6084)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013358.4"
                     /locus_tag="FED44_RS25370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25370"
                     /product="GPR1/FUN34/YaaH family transporter"
                     /protein_id="WP_111699814.1"
                     /transl_table=11
                     /translation="MTATEIPVLPDLNHSTERASAGKQPATADPGLLGYPAFATAAFAL
                     ALFLTGFNQVTIPSTLAAPLPIMSLCGVLLIGATVWAARRGDGWQATMFGLFGAFWLSF
                     SMLVFGLVNSWFGQLPEPAQRGAQANFILVWLGLMTVVTLTTLRLPKIFGLLFLVIDFS
                     LLTLFIAVSVARPGAAGDPWILPFGIIAIFSMPLIGMYLFASTLNTFLGGRQFPVGKPF
                     KS"
     gene            6274..8412
                     /gene="pabB"
                     /locus_tag="FED44_RS25375"
                     /old_locus_tag="FED44_25375"
     CDS             6274..8412
                     /EC_number="2.6.1.85"
                     /GO_function="GO:0046820 - 4-amino-4-deoxychorismate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008153 - para-aminobenzoic acid
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pabB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890426.1"
                     /locus_tag="FED44_RS25375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25375"
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="WP_138462279.1"
                     /transl_table=11
                     /translation="MRTLLIDNHDSYTYNLFQLMARVYGTEPTVVTNDDAAWPGLDIEE
                     FDAIVVSPGPGHPGRDRDLGAVRQVVARTRVPLLGVCLGHQAIALLSGADVVPAPRPRH
                     GHLTRVRHTGEDLFQGLPQDFQAVRYHSLCVPEEGLPDTLTPTAWAEDGVLMGLRHRER
                     PLWGVQFHPESIATEHGAQLVENFGRLAAKALAEQGRSLRPARAPRRVSVQPAPLAPEA
                     PPAAVRPWRLLHRVVPYEVDTAAAFTDLFGGLEHAFWLDSSRVEPGLSRFSFLGAPEGR
                     DGEILSYSVGEGLTIRSGPDPETVTWPDSIFDALRTRLAEPVLDVPDVPFDLTSGYVGY
                     FGYELRAELGSPCRHRAATPDAVWLSATRLVVVDHEQRTTHLIALTRSPDDPAASSWLA
                     RAERRLARWRPPPGADAPAAGGHDPEPGLLRARDGYLDDVEACRGKLREGESYEICLTT
                     QTRLPVTGDPLELYLAQRASNPAPYAAFLRLGGFAVLCSSPERFLRIRPDRTVETKPIK
                     GTAARGRGRREDLRLRARLTTDPKVRAENLMIVDLLRNDLGRVCEVGSVHVPSYMAVET
                     YATVHQLVSTIQGTLRPDVDAIGCVTACFPGGSMTGAPKLRTMEILDEMEQTARGVYSG
                     AIGFLGHNGTADLNIVIRTAVATAEGLTVGAGGAIVLDSDPAEEFEEMLLKARAPLRVA
                     GPPLSASEPGLRWAEAAR"
     misc_feature    complement(6289..6303)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            8409..9866
                     /locus_tag="FED44_RS25380"
                     /old_locus_tag="FED44_25380"
     CDS             8409..9866
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023222.4"
                     /locus_tag="FED44_RS25380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25380"
                     /product="4-hydroxyphenylacetate 3-hydroxylase N-terminal
                     domain-containing protein"
                     /protein_id="WP_117408629.1"
                     /transl_table=11
                     /translation="MTRTGKDYLDALRDGRTIWLDGERVDDLTTHPAFRRSVRSIADLY
                     DLTAEHPETLTASVPGVDGPVSRAYQIPRTKDELKAKGRAFKLWSEATFGFLGRSPDYM
                     ASAVAGMATVPGVLARDGFDGSANLVAHWRRMAEGDLYQAHTLVNPQIDRTKAPSEQME
                     DDLCLRVVAERDDGIVVRGAKMIGTAAALADEILVGVTQRMPPSEADYAVSFSVPVAAP
                     GISFVSRTSYEARATSVFDYPLASRLDENDALVVYDDVFVPWERVFAYRDPEACHAQFW
                     KTPAFVSFVHHGATRFWTKLEFLTGIAILVAKANNVYDMPPVRMQIGKLLSWVNTAKAL
                     VVAAEELCEPVPGADAVMPHRETAYAQLAVGPDLYPKVINEIKLLAGGGLIQLPSSYRD
                     LLRPEVAALLGKYVKSPGYDAEARIKLFKLAWDAVGSEFAGRHDQYERFYHGAPHVYLP
                     ALVREGDPGRYAALADRCLDGYELEDG"
     gene            9863..11647
                     /locus_tag="FED44_RS25385"
                     /old_locus_tag="FED44_25385"
     CDS             9863..11647
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FED44_RS25385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138462280.1"
                     /transl_table=11
                     /translation="MSTARPPMTAVSLLRAYVGSQPAAVAVMAGLLVFSIGLEIAEPRI
                     AAHFIESVQLGRAESVLVGIAGVFLAVAVTRQAARIVSAYASERVSWTATNAAREDLTA
                     HVLSLDLTFHESRPPGELIERIDGDVNQVAEFFSSLIVHIAGNVLLVLGILIALATLDW
                     RVGLTFTAVTILSYLALSRIAGIAGLKWEDDREQSARFFGYVGEATLATEDLRSSGATG
                     YAMARFHRHLRAWLPVKVRAEGWGSAIWVVLSIAFTAGTAIAFGYGGVFYRDGVVSLAG
                     VYLIVAYAAMLNTPMEVLRHQVQTLQQAMAATRRIAELFAHRSSLADGTAAIPSGPLSV
                     RFDHVSFGYGRDDSGDESGDGSKDGSGDGMVMREVSFDVPAGTTLGLVGRTGAGKTTIA
                     SLLFRLYDASRGRVLVGGVDVREASLASLRSRIGFVPQDVQIFDATLRENLTFFDERAD
                     DRRLLEILDVLELRPWLEGLPDGLSSRISPGTLSAGQAQLIALARVFLTDPGLVVLDEP
                     SSRLDPVTEAQVERTLDRMLAGRTAIVIAHRLDTIRRTDQVIVLDTGAIAERGATAGLL
                     ADPGSRLARLYQVGKVLT"
     gene            11644..13431
                     /locus_tag="FED44_RS25390"
                     /old_locus_tag="FED44_25390"
     CDS             11644..13431
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="FED44_RS25390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25390"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138462281.1"
                     /transl_table=11
                     /translation="MNGPAEPSPLGFLWRLITYSPWRYLLAASAWAIFHLWPLLPGVLG
                     KLLFDVLEGRAPAGITVWTVVAIAVGAGLARCVAIVGATVAWAGWYLRARGLIQRNLLA
                     LVFRKPGAQPLPAAAGENISTLRDDSDAIAMMGGWGFDMMSGLIFAGGGLAILLSVDVQ
                     VTLVVMAPLAVVLVLAQLARARAYRIRVRSRAATAQVTGTIQEIVAAVRAIKAAGRERE
                     VVARLRRDNEARKTAMIRDKVQSLAIDSVFNSTASIGSGLILLLAAGRMRSGEFTTGDF
                     VLFSTYLMQVADYTSFMGYLVRTYQQARVSFVRAAAMLPGTPSRTLVEHHPLHLREDAS
                     LTTAPPEPEPLRELEVRSLTHVFPGSGRGVREASFTIRPGTVTVVTGAVGSGKTTLLRT
                     VLGLYAPQDGEIHWNGERVDAPDDFMVPPRVAYTPQNPSLLSGTIRENVLLGLPDDGRV
                     ERAAALAVLGPDLERLGGGLDTEIGVRGVRLSGGQAQRTAAARMFARDSALLVMDDLSS
                     ALDVETEQELWRRIFATSATCLAVSHRPALLERADQVLLLKDGRVVAAGPLAELLRTSP
                     DMRTHYRPAPPTRSRQCHV"
     gene            13419..14924
                     /locus_tag="FED44_RS25395"
                     /old_locus_tag="FED44_25395"
     CDS             13419..14924
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="FED44_RS25395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25395"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_117408632.1"
                     /transl_table=11
                     /translation="MSRVIIVGAGPSGLALAGELAAGGVDCLVVEKRSSRAALSRAFTV
                     EPRTMELLDMRGRVAGLLADGRPCPHPPVGDRNGYLDYGLLDTPFPYSLVVPQHRTEAA
                     LQAAAEQAGAVVRTGAEVVGLRQDAESAEVDVRGPDGVVTTERADYVVGCDGVNSSVRE
                     AIGVDFEGWNYDVSVMMGDMRLRNPPSPPAYARITRRGMVALFPFRDDTYRVIVFDHEK
                     MHVPASLPVTPADLRESCAGILGIDVEPYDPIWLSRFRSSQRHARRYRVGRVLLAGDAA
                     HTHIPSGGQGLQTGIQDAFNLGWKLRAELDGWAPPGLLDSYEDERYPIAAATLRKTDLS
                     FRFETSNGLTARLVRQIVTKLVRVRAIQRVNLEHLSGLTLRYPPGDGGPWAGRRVPDRP
                     LTDGSRLFERFRDGRFVLAAPPGVAVELDGWADRVVTATLAEPIGRGCPPVVLVRPDGH
                     VAWGGRAGAGELAGVLRRWCGEPRRAASGSGQNETAGITRRET"
     misc_feature    14930..14944
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.98"
                     /tool="antismash"
     misc_feature    complement(14937..14951)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(14938..14953)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    14945..14958
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.6"
                     /tool="antismash"
     misc_feature    14946..14959
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.39"
                     /tool="antismash"
     misc_feature    15024..15039
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            15032..15724
                     /locus_tag="FED44_RS25400"
                     /old_locus_tag="FED44_25400"
     CDS             15032..15724
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="FED44_RS25400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25400"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_167521585.1"
                     /transl_table=11
                     /translation="MFDVVNDDPAEVAAIVEFLRSRAGTGPVLEAGIGTGRIGIPLAGT
                     GVEVFGVEVSREMANQLRTKPGAEKVTVEVGDMNEIDFGRKFSLVVLAQGTFGALLSEP
                     AQRAYLRRVPEILTEDGRLVVETMEVDDSRFTHDQYVATSLLDVDHVVLSAALRDPGHQ
                     VLSIQNVLLTAHGIQLYPVKFRYYTAGQLDEMAGDAGLRLLERYSDWTEADYAPGCLRH
                     VSVYGTQD"
     gene            15758..16588
                     /locus_tag="FED44_RS25405"
                     /old_locus_tag="FED44_25405"
     CDS             15758..16588
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037749.4"
                     /locus_tag="FED44_RS25405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25405"
                     /product="DUF5602 domain-containing protein"
                     /protein_id="WP_117408634.1"
                     /transl_table=11
                     /translation="MNISPPRTPRRYTVVVAALGAAVSLTSGCALNLANAKWYTTTYSG
                     EAQTVGHGTARPYVIIDQDGNPTEVGVRLSATALDGLPTEDTVPPTETILEFPKQAKAT
                     VFNHVMLNWYSHGRKPAEIFGEPHFAFHFYTPDHHTVMDIDPKLHPDRAGKVPEKKYIA
                     PDYISEPGNPVEMTKPQMGLHWIDTTRHFGPVGSAEEFREVFVYGSHDGRLIFQEPLAT
                     RKWLLTKPTFKSDIRQPQEYQRSGYYPTFYGIKYDAATNDYVISLGGMRMRKAT"
     gene            16592..17590
                     /locus_tag="FED44_RS25410"
                     /old_locus_tag="FED44_25410"
     CDS             16592..17590
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547526.1"
                     /locus_tag="FED44_RS25410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25410"
                     /product="thiamine pyrophosphate-dependent dehydrogenase E1
                     component subunit alpha"
                     /protein_id="WP_138462283.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-06, bitscore:
                     21.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="DXP_synthase_N (E-value: 4.4e-09,
                     bitscore: 29.9, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTLGPSREAQGPRARAAGAAVPGLPDAVPGLSDDDVAQLVRIR
                     HFERTLLRMFEAGALSGTTHTCIGQEYVPVALAPLLDGDFVVSNHRGHGHYLAHVGDVA
                     GLLAEIMGREGGVCAGVGGSQHLYRPGFLSTGVQGEGVALASGVALRHRRAGTGRIAAV
                     YVGDGTWGEGAVYEALNMAALWRLPVLVVVEDNGIAQSTPTGAHLSGTIAGRARAFGVE
                     YAEIATHDIPAVRAAAGPVIARVRDGGGPAVVRFLTRRLGPHSKGDDTRPAEEVAALWE
                     GDWQAGLEARLGPRFREIDERVRAEVDRIAAEVAARPPSRWADVAEAGAVQ"
     gene            17587..17817
                     /locus_tag="FED44_RS25415"
                     /old_locus_tag="FED44_25415"
     CDS             17587..17817
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (2-67). E-value: 4.4e-09.
                     Score: 28.5. Matches aSDomain:
                     nrpspksdomains_FED44_RS25415_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="FED44_RS25415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25415"
                     /product="acyl carrier protein"
                     /protein_id="WP_117408636.1"
                     /sec_met_domain="PP-binding (E-value: 6.3e-08, bitscore:
                     27.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNELITLVAGVLDVPAETVDENTGTATAAEWSSLRHVQIIGTVER
                     AYGVRLSPREARACRSVGALRDTLRTRGVAV"
     aSDomain        17593..17787
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FED44_RS25415_PP-binding.1"
                     /evalue="4.40E-09"
                     /label="FED44_RS25415_PP-binding.1"
                     /locus_tag="FED44_RS25415"
                     /protein_end="67"
                     /protein_start="2"
                     /score="28.5"
                     /tool="antismash"
                     /translation="ELITLVAGVLDVPAETVDENTGTATAAEWSSLRHVQIIGTVERAY
                     GVRLSPREARACRSVGALRD"
     gene            17814..19982
                     /locus_tag="FED44_RS25420"
                     /old_locus_tag="FED44_25420"
     CDS             17814..19982
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012424.4"
                     /locus_tag="FED44_RS25420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25420"
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_138462284.1"
                     /transl_table=11
                     /translation="MTPLAPRLAESLNGALHRLFAERPGLHLLGEDVADPYGGAFKVTK
                     GLSDRHPGRVLSTPISENGLAGVAAGLALAGDEVVAEVMFGDFAALVFDPVLNLISKSV
                     TMYGRRLPMPVVLRCPVGGRRGYGPTHSQSVQKHFIGMPNLALYELSPFHDPYGLLAHA
                     LDHGPALLFEDKVLYTRRAYPDGVVDEHFRHSLIGDASGWAHVTPADGDAPDVVLICPG
                     GVAHRALAAAHLLRDQGVTAHLLVPGRLYPVDIEPVLPILERPALVAVAEESTAGGTWG
                     SDIAALVYERLWPRLRAPVLRLSSADSIIPAARHLEDRVLLGERHIAEAVAERLGTIAT
                     GAAFVAGPVESVLEPVDAAPPLAVPFVVPKLNNNDTHYLVTCWLAEDGARVEAGAPLVE
                     LETSKAVEEIEAPAAGYLRISADAGTEVEVGAVIAELHELAPPAHAAARSGAGGEAATT
                     AGRGAGSAAPAQAAPPAEPSQPAPSSQPAPSSPADRRIYVLDRVQRGTAAVVTRAHKEV
                     PAAFTAVEVGVDALLARLRLLSEESGAEVGVPEAVVKAVAAAHDRFGHLFGSLVDDRTV
                     AVSETPHVAVTIDAGRGLYTPVIRDCASRSITDIADDLMDFRMKAWRGGDFTTSELDGG
                     TITISINTEADVVFVQPIVMWPQLCMLSVGGLRRQLALHDGVLATTTVVVLGLAYDHRV
                     VNGAEAVAFLRAVADNLREPDRLDQLVA"
     gene            20001..21011
                     /locus_tag="FED44_RS25425"
                     /old_locus_tag="FED44_25425"
     CDS             20001..21011
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF020130.4"
                     /locus_tag="FED44_RS25425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25425"
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_138462285.1"
                     /sec_met_domain="ksIII (E-value: 3.2e-32, bitscore: 105.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFGLIAFAAEVGEPVPVKDVVADYTEDVARVLAYGYDYVHRAAP
                     GMGLTDLAVEAGGQALAAAGVAARDVDLLVLAITDIAEYLYWDAAAAVAHRLGLSWAEA
                     VLVDQGCAGGVTAFDTLAGRFATHLSYDTALVIGANRTTEAYWNRLDTHSLLFSDGAAA
                     AVASRNAASLRWRTSYAETDGRYADFFRLDDGGGAKPFGPGTPPPKVRDAWQIMEHFQY
                     DSDRMAAFADEINDRTARAVHRACKQAGITEDDLAWLLLLNDNPRVIAAQADLIGVPTS
                     RTNIRGARQHGHFGAADHLFELGNLHASGELGLGDYVALATNGRGMHWACTILWS"
     misc_feature    complement(20024..20040)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     CDS             complement(21145..>22153)
                     /NRPS_PKS="Domain: PCP (240-304). E-value: 2.5e-22. Score:
                     70.9. Matches aSDomain: nrpspksdomains_FED44_RS25430_PCP.1"
                     /codon_start=3
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024591.4"
                     /locus_tag="FED44_RS25430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_25430"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_138462286.1"
                     /sec_met_domain="AMP-binding (E-value: 9.8e-41, bitscore:
                     133.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-15, bitscore:
                     51.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNNLYGPTEDTTYSTHAVTDPGAERTPLGRALPGSRVHLLDSDLR
                     PVPLGAIGEVYLSGQGVTRGYHQRPGLTAERYLPLPEGEGGRLYRTGDLARWRPCTTAD
                     GGVEFFLDYHGRVDHQVKLRGFRIEPGEVEHALLQHPAVSEAVVTVHGDHLIAHIATRI
                     PSQDDPVVPEERGEDDEQILLRYLRSCLPQHLVPARIVVMDALPRTPNGKVDRKALPEP
                     TSVPSTGAAEPPGTEAQHLVAELFAGLLGRPVTNIHDDFFSLGGHSLLATRLVSRLNAL
                     TGASLPLRVVFEHPTIAGLAEFLPEPASGPVRPAAIPRLRRTLGRAGAASGVPSD"
     gene            complement(21145..>22157)
                     /locus_tag="FED44_RS25430"
                     /old_locus_tag="FED44_25430"
     aSDomain        complement(21241..21432)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FED44_RS25430_PCP.1"
                     /evalue="2.50E-22"
                     /label="FED44_RS25430_PCP.1"
                     /locus_tag="FED44_RS25430"
                     /protein_end="304"
                     /protein_start="240"
                     /score="70.9"
                     /tool="antismash"
                     /translation="LVAELFAGLLGRPVTNIHDDFFSLGGHSLLATRLVSRLNALTGAS
                     LPLRVVFEHPTIAGLAEFL"
     CDS_motif       complement(21751..21816)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FED44_RS25430_0002"
                     /evalue="3.90E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="FED44_RS25430"
                     /protein_end="134"
                     /protein_start="112"
                     /score="38.0"
                     /tool="antismash"
                     /translation="YHGRVDHQVKLRGFRIEPGEVE"
     CDS_motif       complement(21925..22011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FED44_RS25430_0001"
                     /evalue="1.70E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="FED44_RS25430"
                     /protein_end="76"
                     /protein_start="47"
                     /score="45.9"
                     /tool="antismash"
                     /translation="PLGAIGEVYLSGQGVTRGYHQRPGLTAER"
ORIGIN
        1 cgggccgagc cgggtcagct ccggccgtac agggccggca ggtcgacgag gtggacgtcg
       61 ggggacgcgg ccgtggcggc acgcgccttg tcgttgaacc cggtgccgct gaagcagagc
      121 agacgggtgt ccgtggtgtc gtagcggccc gtccgggcga tcaggtcgcg gaggtgccgg
      181 agtcgttcga tgtgggcggc tcccatcgtg tcgttccact tcgcctcgcc gatggccagc
      241 agcggcgcct tgccgccgtc ggcgatgccg accacggcca cgtcgacctc gtggccggtc
      301 ctggccttgg ggtcgtggac caccccgtga ccgacgcggg cgggcagacc gccgaacagg
      361 tcgggatcgg cgtggtgcag cgcccagtcg cggcagatct gctcgaagtg ggggccgagg
      421 acgttgctga cgaagcggcg gcggctggcc tgccagaccc gcccggcgct gccgggccgc
      481 tccagctggt cccagaccgg gcgcatgatg gcgtggtaga agcggatcaa cggctcggag
      541 atgcggtagg tggcgcggtt gtcccggaac gcgtccgcgt cgcggtgcag caggccggcg
      601 tcctccagca cgttgatcgg atgcgcgatg tccgtcgccc ttcgctccag atagccggcc
      661 actcccccgc gcgtcgcgtt gccgtcggcg acggccgcca ggacggacag gtacagggcg
      721 ctgtcgcgca ggtcgggctc ctcggcgagg agatagcggg cctcccggaa gaggggcgtc
      781 tcggggttga gcacggtgcg gatcacccag tcgtcgaagt cctccggtcc cgacggcgtg
      841 tcaccgcgcg cgaactcgcg acggtaggcg ggggtgccgc cgacgaccgc gttgaccttc
      901 agagccagcg cgggatcgga gatctcccag aactcggcgg ccaggcggtg gtccagtggg
      961 cggacgagca tctccagccc tgcacgcccg cgcagcgggg cgttgccgga cagcagccgg
     1021 cccatgaagg agagggccga cccgcacagc agcaaccggg tgcgcgagcg ggtccgctga
     1081 tcccgcatgg gccggaacgc ctcctggaga agggacggca gttccgggtt ggcccgcgcg
     1141 aggtagggga actcgtcgat gacgacgggg atcggccgct cggcgccgag ggcgagcagc
     1201 gcgtccaaag cctccgacca gtcggcgaag tgatagggga cggcgggccg gacgtgggcg
     1261 gtgagcgcgg cgctcaaccg gcgcagggac tcggcgttcg ccgcctcggt cgcggcgaag
     1321 tagaagccgc ccgcggcacg gcaggcggcg tccagcagga aggtcttgcc ttggcggcgc
     1381 cggccggaga ccacgcctag ggtggcgccg ggctgctcgt cggtgatgaa ccgccgcagc
     1441 gccgaccact cgtagtcacg gtcgaacatc tcggccggct tgtccacatc cacccccgcg
     1501 cttagaggac tacagtttat ataactgtag tcctataagc atgcgggtct tcgtcagtag
     1561 ggcaggacgc ggccggaggg ggtgcgcaga tccaggtcgg cgggcctggg gcggcgtcgc
     1621 ttggccgtga tcctggtcgt ggtcgtggtg gcggtgacgg ctttcgggcg tctcatgggc
     1681 ggcctctcag caccgtgagc accgcgctcc cggatgggcc cggggaggcg cccggggacg
     1741 cggcgggcgg gcgggagcac cgggtgcggg tgccgtcgcg tgagccgtcc cagaagaccc
     1801 agccgcaccg ccggtcgggg cagcgcttca ggcgcggcca ctccccgccg gcggtggtgg
     1861 cgagccaggc ccgggcgatg gcggcgagcg ggtcgtcgga gcggagcgcg aggccgtcca
     1921 ggacggcgtg cgccgcggcc atcgaccggc ggtccggctg ctcgccgtcg gcgagcagcc
     1981 gggcccgcag gccctgccgc agggtgcggg cgcgggccag gtcgtgcggc gtgacgtggg
     2041 cgggcagccc ctgcgcggcc agccaggcgc gcatgccctc cacgctctcc aggaggtcgg
     2101 cgccgcgttc gacgtcgatc gtgttcgcga acgactccag gagcctggtc tcctcaagcg
     2161 gttcccggta gctcatctcg ggctctcagg aggtccggga cctgccgatg agcagggcgg
     2221 cgagcagcgc cgccacggcg aagcccgcac ctgtcaggaa ggtcgcctgc atgccctggc
     2281 tgaacacgta cccgtcgagg gcggccttgg acagaccggc cggcgggtgc tcggtggcgc
     2341 gggtgctcgc cgcggtggcg atgaccacga tcacggcgag ggcgagggag gacccgacgt
     2401 tctggaccat gctcaccacg ctggaggccg cgccggcgtc ctcgctctcc acgcccgagg
     2461 tggcgcggct gaacgcgggg atgatcgcca tggcgacccc ggccccgacg agcaccagcg
     2521 agggcagcac accggtccag tagccgtcgc cgatgtccat ccgcagcagc caggcgttgg
     2581 agatcagcag cagcaccgca ccgatcagca cgaccatccg tccgccgatc ctgggttcga
     2641 ggcggacggc gaggctcgcc gcgccggtca tgccgacgga gacggccagg aaggcgaacg
     2701 cggtggtcag ggtgctgtag ccgaggacga tctggaagta ctggctcagg tagaagaaca
     2761 ggccgatctg cgcgcccggc gtgatcatca gcaccaggta ggccccgacg cggctccggt
     2821 cggtgaacag cccgaggtcg agcagcggct gcctggcccg gcggctgatc agcacgaaca
     2881 gcgcgaggag caccaggccg gccacgacgg agccgatgac ccagccgttg agccagtcgc
     2941 cgccctgcga ggtggtgagc ccgtagacga tcgcgacgac gcccagggtg gcgctcagcg
     3001 cgcccgcgaa gtcgaaccgc ccggggcggc gcggggtctc ctcgatcacc atcgggccca
     3061 gcaccaggag gacgaggccg aagaccgcgc tgggcagcag caccacgcgc caggaactga
     3121 tcgtgccgag cagccccacc agcatcagcc cgacggcggc gcccgcgccg cccgcgatcg
     3181 tgtacgcgct gatggcccgg cggcgcagcg ggccctcctc gaacatgctc acgatcaggg
     3241 ccagcacgca cggtgtggcc agcgccgcgc ccacgccctg ggccccccgg gcggcgatga
     3301 ccagccaggc gtccggagcg atcgcgcgca ccaggcagcc cgcggtgtag aaggccacgc
     3361 cggcgacgaa cacccggcgc ttgccgagga tgtcgccggc cctgccgccg agcagcagca
     3421 ggccgccgta cgggaggagg taggcgttga cgacccagga gagctgggtc tgggacatct
     3481 cgagcgcctg gccgataccg gccagcgaga tgctgatcac catctcgtcg accatgatga
     3541 gcgcccagaa ggccaccacg acggacaggg cgatcaggct cttgcccctg attccgtcgg
     3601 ggacggtccg ggttgacgga tgagtgagca tggagatcct ccggctccgg attcgcgccg
     3661 cgggcgcgtg gtgtgctttg tgctggtgct aggagggcag gccgatggac aggccgtgcc
     3721 ggaagacgtt ccgcgggtcg tactgcctct tgatccgctg cagtcttggg tagttgtcgc
     3781 ggtagtagag cgcgtgccag ggagtgccgg aggtgttcca cgccgggtcg gccaggtccc
     3841 tgtcggggta gttgatgaac gccccgccgt tgacggcgtt cggcacgggc accccgccgg
     3901 tgtcctggta gagctcccgg tagaggttcc ggatccaggc catgttggcc tcgtcctcgt
     3961 acgagctgct ccagccgccg gcggtgaagt agacccgcag gacggagtcg cggtggacgg
     4021 ccgcggtcgc gccggacgcc acgctgttga tccgcccgcc gaagccggtg atgttcacca
     4081 gggcgttggg gttgtagtag gagtcgtcgc tgagatgccg gtagagcgtc gcgatctgcg
     4141 cgggggtgta gctgcggcgc aggtcggcgg tcttgttctt ctgacggccc gcggggtcgc
     4201 tgacccagtt gcgggggtcg agccaggggg tggtctcctg gacgtcgacc atcggctcga
     4261 cgccgacccc ggaggtgacg gcggcgaagt gggcgtccag cagcgcctgg ccgcccgaca
     4321 ccgactcgtc cacgcccgcc agcagcatca gcgtcccggc cgaacggtgg ttggtggtga
     4381 gggtgcccca caggttgacc gccgggctgc cgggtgcgct gttgttctgg taccaggtgc
     4441 agtagttgcc gaccagggtg gtgaaggcct gctcggtcat cgcgtcccac gaccacatca
     4501 gcaggcgggc ccgctggttg ccgatccggg gcaggagcct ggtggggtcg ttggacgtca
     4561 cgcccggcgt cctgaaccag tagcgggtga cgatgccgaa gttgccggcg ccgccgccgg
     4621 tgtgcgccca gaacaggtcg cggttggggt cggacgggct gtccgtggcg acgatgacgc
     4681 ggggtgtgcc cgaggcgtcg acggtgacga cctcgaccgc gttcaggtgg tcgacgctga
     4741 ggccgtgctt gcgggagaag aagccgtagc cgccgccggg gatgtgccct ccgatgccga
     4801 cggtcgcgca gccggtgaag gggatcatca cgccccagcc cttgaagagg gtctcggcca
     4861 cctcgccgac gagggcgccg ggctccacgg cgaaggcccc gcgacgcgcg tcgtggtaga
     4921 ccgccgtcat ctgggacagg tcgatgaccg ccttgatgtc ggaggtggtg gtgaagtcct
     4981 ccatgcagtg gccgccggag cgggcgacca gccgcttgcc cgccgccacg gccgcgccga
     5041 ccgcgtccac gacctgcgcg gccgagccca ccacggtcac ctggtcgggc gcgccggtga
     5101 agcgcatgtt gtgcccgctg cgcatgctgt cgaagcgggg atcgccgggc cggacgacga
     5161 aggggccgaa ctcgggcacg caccggacgc cggtggttcc cgcggacgcc ggtgtgccgc
     5221 ccagggcgac ccccgaggcc aggccggccc cggccgccgc cgcgccggcc aggaatcccc
     5281 ggcggttgta tacggtcacg ctttccactc ctcaatcagc gaattacccg acctcggcgg
     5341 gcgccttctc cgacgcccgc cagatcgagt ggtttcgttt tttccagacc gtactacttc
     5401 gagccggttt cagctcttga acggcttgcc caccgggaac tgcctgccgc cgaggaaggt
     5461 gttcagcgtg ctggcgaaca ggtacatgcc gatcagcggc atcgagaaaa tcgcgatgat
     5521 gccgaagggg aggatccacg ggtcacccgc ggcaccgggc cgcgccacgc tgacggcgat
     5581 gaacagcgtc agcagcgaga agtcgatgac gaggaacagc agcccgaaga tcttcggaag
     5641 ccggagcgtg gtgagggtca ccacggtcat gagcccgagc cagaccagga tgaagttggc
     5701 ctgggcgccg cgctgcgcgg gctcggggag ctgaccgaac cagctgttga cgagaccgaa
     5761 cacgagcatc gagaagctca gccaaaaagc accgaacagg ccgaacatgg tcgcctgcca
     5821 gccgtcgccg cggcgggccg cccagaccgt ggcgccgatg aggagcacgc cgcagaggga
     5881 catgatcggc agcggggcgg cgagcgtgct ggggatggtg acctggttga aaccggtcag
     5941 gaacagggcc agcgcgaacg ccgcggtggc gaaggcgggg tacccgagga gacccgggtc
     6001 ggcggtcgcc ggctgctttc cggcgctggc ccgctccgtc gagtggttga ggtcggggag
     6061 tacggggatt tcggtggcgg tcataggact ctccggtcgc cgggattctg gcgtcgtgaa
     6121 cgtattcgcg gtggatatcc attgccgtat caatccgctc tcgcccgccg ggcccgcctc
     6181 tcagcccgct ctcagcccgc tcttttcgca ttgtccacga ccaggccgcg gtttatgcaa
     6241 gtcgtagctt tactggtcga gatgagggac cgtatgcgta cgctactgat cgacaaccat
     6301 gattcgtaca cctacaacct ctttcaactg atggcccggg tgtacggcac ggagccgacg
     6361 gtggtgacga acgacgacgc cgcgtggccc ggtctggaca tcgaggagtt cgacgcgatc
     6421 gtcgtctccc ccggccccgg ccatccgggc cgggaccgcg acctcggcgc ggtccggcag
     6481 gtggtggcgc gcaccagggt cccgcttctc ggggtctgcc tcggtcacca ggcgatcgcg
     6541 ttgctctcgg gagccgacgt ggtgcccgcg ccccggcccc ggcacggtca cctgacccgc
     6601 gtgcggcaca ccggcgagga cctcttccag ggactgcccc aggacttcca ggcggtgcgc
     6661 taccactcgc tgtgcgtgcc ggaggagggt ctgcccgaca ccctcacgcc gacggcgtgg
     6721 gcggaggacg gcgtgctcat ggggctgcgg caccgggagc ggccgctgtg gggggtgcag
     6781 ttccaccccg agtcgatcgc gaccgagcac ggcgcgcaac tggtcgagaa cttcggccgt
     6841 ctcgcggcga aggcgctggc ggaacagggc aggtcactgc gcccggcgcg ggcgccgcga
     6901 cgggtgtccg tccagccggc gcccctcgcg cccgaggcgc cgcccgccgc cgtgcgcccg
     6961 tggcggctgc tgcaccgcgt ggtgccgtac gaggtggaca cggcggcggc gttcacggac
     7021 ctgttcggcg gcctggagca cgcgttctgg ctggacagca gccgggtgga gcccggcctg
     7081 tcgcggttct ccttcctcgg cgcgccggag ggccgcgacg gcgagatcct gagctactcc
     7141 gtcggcgaag ggctcacgat ccggagcggg ccggacccgg agaccgtcac ctggccggat
     7201 tcgatcttcg atgccctccg gacccggctc gccgagccgg tcctcgacgt ccccgacgtg
     7261 cccttcgacc tcaccagcgg atacgtgggc tacttcggct acgagctgag ggccgaactg
     7321 ggctcgccgt gccggcaccg cgccgccacg cccgacgcgg tgtggctgtc cgccacccgc
     7381 ctggtggtgg tcgaccacga gcagcggacc acccatctca tcgcgctgac ccggtcgccg
     7441 gacgaccccg ccgcgtcgtc gtggctggcc cgcgccgaac ggcggctcgc ccggtggcgg
     7501 ccgccaccgg gagcggacgc gcccgccgca ggcggccacg accccgagcc cggcctgctc
     7561 cgcgcccggg acggctacct ggacgacgtc gaggcgtgcc ggggcaagct gcgcgagggc
     7621 gagagctacg agatctgcct gaccacgcag acccggctgc ccgtgaccgg cgacccgctg
     7681 gagctgtacc tcgcgcagcg cgcgtccaac cccgcgccgt acgcggcctt cctgcggctg
     7741 ggcggcttcg ccgtcctctg ctcgtccccc gagcggttcc tgcggatccg gccggaccgg
     7801 accgtggaga cgaaaccgat caagggcacc gcggcccggg gtcgcgggcg ccgggaggac
     7861 ctgcggctgc gcgcccggct gacgaccgat cccaaggtca gggccgagaa cctgatgatc
     7921 gtggacctgc tgcgcaacga cctcgggcgg gtctgcgagg tcggctccgt ccacgtgccc
     7981 agctacatgg cggtcgagac gtacgcgacc gtccaccagc tcgtgtccac gatccagggc
     8041 acgctccgcc cggacgtcga cgccatcggc tgcgtcacgg cgtgcttccc cggcgggtcg
     8101 atgaccggcg cgcccaagct gcgcacgatg gagatcctcg acgagatgga gcagacggcg
     8161 cgcggggtct actccggcgc catcggcttc ctcggccaca acggcacggc cgacctcaac
     8221 atcgtcatcc gcaccgcggt ggcaaccgcc gagggcctga cggtgggggc gggcggcgcg
     8281 atcgtgctcg actccgatcc tgccgaggag ttcgaggaga tgctgctgaa ggcgcgggcg
     8341 cccctccgcg tggccgggcc cccgctgtcg gcgtcggaac cagggctgcg ctgggcggag
     8401 gcggcacgat gaccaggacc ggcaaggact acctcgacgc gctgcgcgac ggcaggacga
     8461 tctggctgga cggcgagcgg gtggacgacc tgaccacgca tcccgccttc cggcgttcgg
     8521 tccgctcgat cgccgacctc tacgacctga cggcggagca ccccgagacg ctgacggcgt
     8581 cggtgcccgg cgtcgacggg ccggtgtcgc gcgcctacca gatcccgcgt acgaaggacg
     8641 agctcaaggc caagggccgg gcgttcaagc tgtggtcgga ggcgacgttc ggattcctcg
     8701 gccgctcccc cgactacatg gcctcggccg tcgccgggat ggcgaccgtg ccgggcgtgc
     8761 tggcccgcga cgggttcgac ggctcggcca acctggtcgc gcactggcgg cggatggccg
     8821 agggcgacct ctaccaggcg cacacgctgg tcaacccgca gatcgaccgc acgaaggcgc
     8881 cgtcggagca gatggaggac gacctgtgcc tgcgggtcgt cgccgagcgc gacgacggga
     8941 tcgtcgtgcg cggcgccaag atgatcggca ccgcggcggc cctcgccgac gagatcctgg
     9001 tcggcgtcac ccagcggatg ccgcccagcg aggccgacta cgcggtgagc ttctcggtgc
     9061 cggtcgcggc gcccggcatc tctttcgtca gccggacctc ctacgaggcc cgcgccacca
     9121 gcgtcttcga ctacccgctc gccagccggc tggacgagaa cgacgcgctc gtggtctacg
     9181 acgacgtgtt cgtgccgtgg gagcgggtgt tcgcctaccg cgacccggag gcctgccacg
     9241 cgcagttctg gaagaccccg gcgttcgtca gcttcgtcca ccacggcgcc acccggttct
     9301 ggaccaagct ggagttcctc accgggatcg ccatcctcgt cgccaaggcc aacaacgtct
     9361 acgacatgcc gccggtgcgg atgcagatcg gcaagctgct gtcgtgggtg aacaccgcca
     9421 aggcgctggt cgtcgccgcc gaggagctgt gcgagccggt gcccggcgcc gacgcggtca
     9481 tgccgcaccg tgagacggcg tacgcccagc tcgccgtggg accggacctc taccccaagg
     9541 tgatcaacga gatcaagctg ctggcgggcg gcgggctgat ccagctgccg tcctcctacc
     9601 gcgacctgct gcgcccggag gtcgccgcgc tcctcggcaa gtacgtgaaa tcccccgggt
     9661 acgacgccga ggcgcggatc aagctgttca agctggcctg ggacgccgtc ggcagcgagt
     9721 tcgccgggcg gcacgaccag tacgagcgct tctaccacgg ggcgccgcac gtgtacctgc
     9781 ccgccctcgt gcgcgagggc gaccccggcc ggtacgccgc gctggccgac cggtgcctcg
     9841 acggctacga actggaggac gggtgagcac cgcccggccg ccgatgaccg ccgtctccct
     9901 cctgcgcgcc tacgtggggt cgcagccggc ggccgtcgcg gtgatggccg gtctgctggt
     9961 cttctccatc ggcctggaga tcgcggagcc gcgcatcgcc gcgcacttca tcgagtcggt
    10021 ccagctcggc cgggccgaga gcgtgctcgt cgggatcgcc ggggtgttcc tggccgtggc
    10081 cgtgacgcgg caggccgccc gcatcgtgtc ggcgtacgcc agtgagcggg tctcgtggac
    10141 cgccaccaac gccgcccgcg aggacctgac cgcgcacgtg ctgtcgctcg acctgacctt
    10201 ccacgagtcc cgcccgcccg gcgagctcat cgagcgcatc gacggcgacg tcaaccaggt
    10261 cgcggagttc ttctccagcc tgatcgtgca catcgccggc aacgtcctgc tggtgctggg
    10321 catcctgatc gccctggcca ccctggactg gcgggtcggg ctcaccttca ccgcggtcac
    10381 gatcctcagc tatctggcgc tgtcgaggat cgccgggatc gccgggctca aatgggagga
    10441 cgaccgggag cagagcgccc ggttcttcgg ctacgtcggc gaggcgaccc tcgccaccga
    10501 ggacctgcgc tcgtccggcg ccaccggcta tgccatggcg cgcttccacc ggcacctgcg
    10561 cgcgtggctg ccggtgaagg tcagggccga gggctggggc agcgccatct gggtcgtgct
    10621 ctcgatcgcg ttcaccgccg gcacggcgat cgccttcggg tacggcggcg tcttctaccg
    10681 cgacggcgtg gtgtccctgg ccggcgtcta cctgatcgtc gcgtacgcgg cgatgctgaa
    10741 cacccccatg gaggtgctgc gccaccaggt gcagacgctc cagcaggcga tggccgcgac
    10801 gcggcgcatc gccgagctgt tcgcgcaccg gtcctccctc gccgacggga ccgcggccat
    10861 cccctccggc ccgctgtccg tccggttcga ccacgtcagc ttcggctacg gccgggacga
    10921 ctccggggac gagtccggcg acggctccaa ggacggctcc ggggacggca tggtcatgcg
    10981 cgaggtgtcg ttcgacgtcc cggcggggac cacgctcggg ctcgtcgggc ggaccggcgc
    11041 gggcaagacc accatcgcct ccctgctgtt ccgcctgtac gacgcgagcc ggggacgggt
    11101 gctggtcggc ggggtcgacg tccgcgaggc ctccctggcg tcgctgcggt cgcggatcgg
    11161 gttcgtgccg caggacgtgc agatcttcga cgccaccctg cgggagaacc tgaccttctt
    11221 cgacgagcgg gccgacgacc ggcggctgct ggagatcctc gacgtgctgg agctgcggcc
    11281 ctggctggag gggctgcccg acgggctgtc ctcgcggatc tctcccggca ccctgtcggc
    11341 cgggcaggcg cagctcatcg ccctggcccg ggtgttcctg accgatccgg ggctggtcgt
    11401 gctcgacgag ccgtccagca ggctcgaccc ggtcaccgag gctcaggtgg aacgcacgct
    11461 cgaccgcatg ctcgccgggc gcaccgcgat cgtgatcgcc caccggctcg acacgatccg
    11521 ccgtacggac caggtgatcg tgctggacac cggcgcgatc gccgagcggg gcgccaccgc
    11581 cggcctgctg gccgacccgg gctcccggct ggcgcggctc taccaggtcg ggaaggtgct
    11641 cacatgaacg gaccggccga gccgtccccg ctggggttcc tctggcggct gatcacctac
    11701 agcccctggc gctacctgct ggccgcctcc gcgtgggcca tcttccatct gtggccgctg
    11761 ctgcccggcg tgctgggcaa gctgctgttc gacgtcctgg agggccgggc gcccgccggg
    11821 atcaccgtgt ggacggtggt ggcgatcgcg gtgggcgcgg gcctggcccg gtgcgtcgcg
    11881 atcgtcggcg cgaccgtggc ctgggcgggc tggtacctgc gcgcccgggg gctgatccag
    11941 cgcaacctgc tcgccctggt gttccgcaag ccgggcgcgc agccgctgcc ggccgccgcg
    12001 ggcgagaaca tctccaccct gcgggacgac agcgacgcca tcgcgatgat gggcggctgg
    12061 ggcttcgaca tgatgtccgg gctcatcttc gcgggcggcg ggctggcgat cctgctcagc
    12121 gtcgacgtcc aggtgaccct cgtcgtcatg gcgccgctcg cggtcgtcct ggtcctcgcg
    12181 cagctggcgc gcgcccgggc gtaccgcatc cgggtgcgca gcagggcggc caccgcccag
    12241 gtcaccggga ccatccagga gatcgtggcc gcggtccgcg cgatcaaggc ggcgggccgg
    12301 gaacgcgagg tcgtcgcccg gctgcgccgt gacaacgagg cacgcaagac cgcgatgatc
    12361 cgcgacaagg tgcagagcct cgccatcgac tccgtcttca acagcaccgc gagcatcggc
    12421 tccggcctga tcttgctgct tgcggcgggc cggatgcgct ccggcgagtt caccaccggc
    12481 gacttcgtgc tgttctccac ctatctgatg caggtggccg actacacgtc cttcatgggc
    12541 tacctcgtgc gcacctacca gcaggcccgg gtctcgttcg taagggcggc cgccatgctg
    12601 cccggcacgc cctcgcggac gctggtcgag caccacccgc tgcacctgcg cgaggacgcg
    12661 tccctcacca cggcgccgcc ggaaccggag ccgctgcgcg agctggaggt gcggtcgctg
    12721 acgcacgtct tccccggctc cgggcggggc gtgcgcgagg cgtccttcac gatccggccg
    12781 ggcaccgtca ccgtcgtgac cggcgcggtg gggtcgggca agacgacgct gctgcgcacc
    12841 gtgctcggcc tctacgcgcc gcaggacggc gagatccact ggaacggcga gcgggtcgac
    12901 gccccggacg acttcatggt gccgccgcgc gtcgcctaca ccccgcagaa cccctccctg
    12961 ctgtccggca cgatcaggga gaacgtgctg ctcggcctgc cggacgacgg ccgggtcgaa
    13021 cgggcggcgg ccctcgcggt gctcggcccg gacctggagc ggctcggcgg cgggctcgac
    13081 acggagatcg gcgtacgcgg cgtgcgcctc tccggcgggc aggcgcagcg cacggcggcc
    13141 gcccggatgt tcgcccgcga cagcgcgctg ctggtcatgg acgacctgtc cagcgccctc
    13201 gacgtggaga ccgagcagga gctgtggcgg cgcatcttcg ccacgtcggc gacctgcctc
    13261 gccgtctccc accggcccgc cctgctggag cgggccgacc aggtgctgct gctgaaggac
    13321 ggccgggtcg tcgccgcggg cccgctggcc gagctgctgc ggacgtcccc ggacatgcgg
    13381 acgcactacc gccccgcccc gccaacgagg agtcgacagt gtcacgtgtg atcatcgtcg
    13441 gcgccggccc ctccgggctg gcgctggccg gcgagctggc ggcgggcggt gtcgactgcc
    13501 tcgtggtgga gaagcggtcg agccgcgccg ccctgtcccg ggccttcacc gtggaacccc
    13561 gcacgatgga gttgctcgac atgcgcggcc gggtcgccgg gctgctggcc gacggccgtc
    13621 cctgcccgca ccccccggtg ggcgaccgga acggctacct cgactacggc ctgctcgaca
    13681 cgccgttccc gtacagcctg gtcgtgccgc agcaccgcac cgaggccgcc ctgcaggccg
    13741 ccgccgagca ggccggcgcg gtggtccgca ccggcgccga ggtggtcggc ctgcgccagg
    13801 acgcggagtc cgccgaggtc gacgtacgcg gcccggacgg cgtggtgacg accgagcgcg
    13861 ccgactacgt ggtcggctgc gacggcgtga acagcagcgt gcgcgaggcg atcggcgtcg
    13921 acttcgaggg ctggaactac gacgtgtcgg tcatgatggg cgacatgcgg ctgcgcaacc
    13981 cgccgtcgcc gcccgcctac gcccgcatca cccgccgggg catggtggcg ctgttcccct
    14041 tcagggacga cacctaccgg gtcatcgtgt tcgaccacga gaagatgcac gtcccggcct
    14101 cgctgccggt gaccccggcg gacctgcggg agagctgcgc gggcatcctc ggcatcgacg
    14161 tcgagccgta cgacccgatc tggctgtcgc ggttccgcag ctcgcagcgc cacgcccggc
    14221 gctaccgcgt cggccgggtg ctgctggccg gggacgccgc ccacacgcac atcccctccg
    14281 gcggccaggg cctgcagacg ggcatccagg acgcgttcaa cctcggctgg aagctccgcg
    14341 cggagctcga cggctgggcc ccgccgggcc tcctggacag ctacgaggac gagcgctacc
    14401 cgatcgccgc ggcgaccctg cgcaagaccg acctctcctt ccgcttcgag acctcgaacg
    14461 gcctgaccgc acggctggtc cgccagatcg tcacgaagct cgtacgcgtc cgcgcgatcc
    14521 agcgggtgaa cctggagcac ctgtccgggc tcacgctgcg ctacccgccg ggcgacggcg
    14581 ggccctgggc cgggcggcgg gtccccgacc ggccgctgac cgacggctcg cggctgttcg
    14641 agcggttccg ggacggccgg ttcgtgctgg ccgcccctcc cggcgtcgcc gtcgagctgg
    14701 acggctgggc cgaccgggtc gtcaccgcga ccctcgcgga gccgatcggc cggggatgcc
    14761 cgcccgtggt cctcgtccgg cccgacggtc acgtggcgtg gggcgggcgg gcaggcgccg
    14821 gcgaactcgc gggggtgctc cgccgctggt gcggcgagcc gcgccgcgcg gcgagcggct
    14881 ccggccagaa cgagaccgcc ggtatcacgc ggagagaaac gtgagagccg cttttccgac
    14941 aatgaattgc acataaaaag cgtcggaaaa ctgccggagg cgggccatgc gaaactattc
    15001 agccgaatcg tatggcgatg ccatcgcctc cgtgttcgac gtcgtgaacg acgacccggc
    15061 ggaagtggcc gccatcgtgg agttcctgcg tagtcgtgcg gggaccggcc cggtgctgga
    15121 agcgggcatc gggacgggaa ggatcggcat cccgctggcg gggaccggcg tcgaggtgtt
    15181 cggcgtggaa gtcagccggg aaatggccaa ccagcttcgc acgaagccgg gcgcggaaaa
    15241 ggtgaccgtc gaagtcggcg acatgaatga aatcgacttc gggcggaagt tctcgctcgt
    15301 cgtcctcgcg cagggcacct tcggcgcgct gctgtcggaa ccggcgcagc gcgcgtacct
    15361 gcggcgggtc ccggagatcc tcaccgagga cggccggctc gtcgtggaga cgatggaggt
    15421 ggacgactcc cgcttcaccc acgaccagta cgtcgccacg tcactgctcg acgtcgacca
    15481 cgtggtgctc agcgcggcgc tccgcgaccc cgggcaccag gtgctgagca tccagaacgt
    15541 gctgctcacc gcgcacggca tccagctcta ccccgtgaag ttccggtact acaccgccgg
    15601 gcagctcgac gagatggcgg gtgacgcggg actgcggctg ctcgaacgct actccgactg
    15661 gaccgaagcc gactacgcgc cgggctgcct ccggcacgtc tcggtctacg gcacccagga
    15721 ctgaacgacc cgtcaccgtc tggaaggcga ctcgccgatg aacatctcac cccccaggac
    15781 gccgcggcgc tacaccgtcg tggtcgcggc gctcggcgcc gcggtatccc tcaccagcgg
    15841 ttgcgccctg aacctcgcca acgccaagtg gtacaccacc acctactcgg gcgaggcgca
    15901 gaccgtgggc cacggcaccg cgcggccgta cgtcatcatc gaccaggacg gcaaccccac
    15961 ggaggtcggg gtgcgcctgt cggcgacggc gctggacggg ctgcccaccg aggacaccgt
    16021 cccgccgacg gagaccatcc tggagttccc caagcaggcg aaggccaccg tcttcaacca
    16081 cgtgatgctc aactggtaca gccacggacg gaagccggcc gagatcttcg gcgagccgca
    16141 cttcgccttc cacttctaca cgcccgacca ccacacggtg atggacatcg accccaagct
    16201 ccacccggac cgcgccggga aggtgccgga gaagaagtac atcgcgcccg actacatctc
    16261 cgagccgggc aacccggtgg agatgaccaa gccccagatg ggactgcact ggatcgacac
    16321 gacgcggcac ttcgggccgg tcggcagcgc cgaggagttc cgcgaggtct tcgtctacgg
    16381 ctcccacgac ggcaggctca tcttccagga gccgctcgcg acgcggaagt ggctgctgac
    16441 caagcccacc ttcaagtccg acatccggca gccgcaggag taccagcgca gcggctacta
    16501 cccgaccttc tacggcatca agtacgacgc cgccaccaac gactacgtga tctcgctggg
    16561 cggcatgcgg atgcgtaagg cgacgtaggt cgtgtccggc accctcggcc cgtcgcgcga
    16621 ggcccaaggc ccccgggccc gcgcggcggg cgccgccgtc cccggcctgc cggacgccgt
    16681 gcccggcctg tcagacgacg acgtggcgca actggtccgc atccgccact tcgagcggac
    16741 cctgctgcgg atgttcgagg ccggcgcgct gagcgggacc acgcacacgt gcatcgggca
    16801 ggagtacgtg ccggtggcgc tggccccgct gctcgacggc gacttcgtgg tcagcaacca
    16861 ccgtggtcac ggccactacc tggcccacgt cggcgacgtc gccgggctgc tcgccgagat
    16921 catgggccgg gagggcgggg tctgcgccgg cgtcggcggc agccagcacc tctaccggcc
    16981 cggcttcctg tccaccggtg tgcagggcga gggcgtggcg ctcgcgtcag gcgtcgcgct
    17041 gcggcaccgg cgcgccggca ccggccggat cgccgccgtc tacgtcggcg acggcacctg
    17101 gggcgagggc gcggtgtacg aggcgctcaa catggcggcg ctgtggcggc tgccggtgct
    17161 ggtcgtcgtg gaggacaacg ggatcgccca gtccaccccc accggcgcgc acctctccgg
    17221 gaccatcgcc ggccgggcgc gcgccttcgg cgtcgagtac gccgagatcg ccacccatga
    17281 catcccggcc gtccgcgccg cagccgggcc ggtgatcgcg cgggtccgcg acggcggcgg
    17341 gccggcggtc gtacggttcc tgacccggcg gctcggcccg cacagcaagg gcgacgacac
    17401 ccgccccgcc gaggaggtcg cggccctgtg ggagggcgac tggcaggcgg ggctggaggc
    17461 gcgcctcggt ccccgcttcc gggagatcga cgagcgggtc cgcgccgagg tggaccggat
    17521 cgccgccgag gtggcggcac gcccgccgtc gcggtgggcc gacgtggccg aggcgggagc
    17581 cgtacagtga acgaactgat caccctggtc gcgggcgtcc tcgacgtgcc cgccgagacg
    17641 gtcgacgaga acaccggcac ggccacggcc gccgagtgga gcagcctgcg ccacgtgcag
    17701 atcatcggca ccgtcgaacg ggcgtacggc gtgcggctga gcccgcgcga ggcccgcgcg
    17761 tgccgctccg tgggggcgct gcgggacacc ctgcggacgc gcggagtcgc ggtatgacac
    17821 cgctcgcgcc ccggctcgcg gagagcctga acggcgcgct gcaccggctg ttcgccgaac
    17881 gccccggcct gcacctcctc ggcgaggacg tcgccgatcc ctacggtggc gccttcaagg
    17941 tcaccaaggg gctgtcggac cggcatcccg gccgcgtgct gtccaccccg atcagcgaga
    18001 acggcctcgc gggcgtcgcg gccggtctcg ccctcgccgg tgacgaggtc gtggccgagg
    18061 tcatgttcgg cgacttcgcc gcgctcgtct tcgacccggt gctcaacctg atctcgaagt
    18121 cggtgacgat gtacggccgg cggctgccca tgccggtcgt gctccgctgc ccggtcggcg
    18181 gccgtcgcgg ctacgggccc acccacagcc agagcgtgca gaagcacttc atcggcatgc
    18241 cgaacctggc gttgtacgag ctcagcccgt tccacgatcc gtacgggctg ctcgcgcacg
    18301 ccctggacca cgggcccgcg ctgctcttcg aggacaaggt gctctacacc cggcgggcgt
    18361 accccgacgg ggtcgtggac gagcacttcc gccactcgct catcggggac gcgtccggct
    18421 gggcgcacgt gacccccgcg gacggcgacg cccccgacgt cgtgctgatc tgcccgggcg
    18481 gcgtcgccca ccgggcgctc gccgccgccc acctcctgcg ggaccagggc gtcaccgcgc
    18541 accttctggt ccccgggcgc ctgtaccccg tggacatcga gcccgtcctg ccgatcctgg
    18601 aacggcccgc gctcgtggcc gtcgccgagg agagcacggc gggcggcacc tggggctccg
    18661 acatcgcggc gctggtgtac gagcggctgt ggccacgcct gcgcgccccg gtgctgcggc
    18721 tgtcgtccgc cgactcgatc atcccggccg ctcgtcacct ggaggaccgg gtgctgctgg
    18781 gcgaacggca catcgccgag gccgtcgcgg agcgcctcgg cacgatcgcg acgggcgccg
    18841 cgttcgtcgc cgggcccgtc gagtctgttc ttgagcccgt cgatgccgcc ccaccgctcg
    18901 ccgtgccttt cgtcgtgccg aagctgaaca acaacgacac gcactacctg gtgacctgct
    18961 ggctcgccga ggacggggcg agggtcgagg cgggcgctcc cctggtcgaa ctggagacgt
    19021 ccaaggcggt cgaggagatc gaggccccgg ctgccggata tctgcggatc tcggccgacg
    19081 ccggcaccga ggtggaggtc ggcgccgtca tcgcggaact gcacgaactc gcgcccccgg
    19141 cgcatgcggc ggcgaggagc ggagcgggcg gcgaggcggc tacgaccgcc ggtcgtggtg
    19201 cgggatcggc ggcgcccgcg caggccgctc cgcccgccga gccttcccag cccgccccgt
    19261 cgtcccagcc cgccccgtcg tccccggccg accggcggat ctacgtgctc gaccgggtgc
    19321 agcggggcac cgccgccgtc gtgacccggg cccacaagga ggtgccggcg gccttcaccg
    19381 ccgtcgaggt gggggtcgac gccctcctcg ccagactgcg tctgctctcg gaggagtccg
    19441 gcgccgaggt cggcgtaccc gaggccgtgg tgaaggcggt cgccgccgcc cacgaccgct
    19501 tcggccacct cttcggcagc ctcgtggacg accggacggt cgccgtctcc gagacacctc
    19561 acgtcgcggt gacgatcgac gcgggacgcg gcctctacac gcccgtgatc cgggactgcg
    19621 cgagccgatc gatcaccgat atcgccgacg acctgatgga tttccggatg aaagcgtggc
    19681 gaggaggcga tttcaccact tccgagctcg atggcggtac gatcaccatc tcgatcaaca
    19741 ctgaggccga tgtggtgttc gtacaaccga tcgtcatgtg gccgcagttg tgcatgctct
    19801 ccgtcggcgg gctacgtcgg cagctcgcgc tccacgacgg agtcctcgcg acaaccacgg
    19861 tcgtcgtcct cggcctcgcc tatgaccacc gggtcgtgaa cggcgccgaa gcggtggcct
    19921 tcctgcgagc ggtcgcggac aacctccgcg agccggaccg gctcgaccag ctggtcgcct
    19981 gacggcgtga tggaggactg atgacgttcg ggctgatcgc cttcgccgcg gaagtgggcg
    20041 agccagtgcc cgtcaaggat gtggtcgcgg attacaccga ggacgtcgcg cgtgtgctcg
    20101 cgtacggcta cgactacgtg caccgcgcgg ctcccgggat gggcctgacc gatctcgccg
    20161 tcgaagcggg cgggcaggcc ctcgccgcgg cgggcgtcgc cgcccgcgac gtcgacctcc
    20221 tggtgttggc gatcacagac atcgcggagt acctgtactg ggacgcggcg gccgcggtcg
    20281 cccaccggct cggcctctcc tgggcggagg ccgtactggt ggaccagggc tgcgcgggcg
    20341 gcgtcaccgc cttcgacacc ctggccggcc ggttcgccac ccacctgtcc tacgacaccg
    20401 ccctggtcat cggcgccaac cgcaccaccg aggcgtactg gaaccgcctg gacacccact
    20461 cgctgctgtt ctccgacggc gcggcggcgg ccgtggccag ccgcaacgcc gcgtcactgc
    20521 gctggcgcac gtcgtacgcc gagacggacg gacgctacgc cgacttcttc cgcctcgacg
    20581 acggcggcgg ggcgaagccc ttcgggcccg gcacgccgcc tcccaaggtc cgggacgcct
    20641 ggcagatcat ggagcacttc cagtacgact ccgaccgcat ggccgccttc gcggacgaga
    20701 tcaacgaccg tacggcccgt gccgtccacc gcgcctgcaa gcaggccggc atcacggagg
    20761 acgacctcgc gtggctcctc ctgctcaacg acaatcctcg tgtcatcgcc gcccaggccg
    20821 atctgatcgg tgtgccgacg tcccgtacga acatccgcgg cgcccggcag cacgggcact
    20881 tcggtgccgc cgaccacctg ttcgagctgg gcaacctgca cgcctcaggg gagctgggcc
    20941 tgggtgacta cgtggcgctg gccacgaacg gccgcggaat gcactgggcg tgcacgatcc
    21001 tgtggtcctg acccacgcct tggcctggat tggccctgat cgggcctgat cgcccgctcc
    21061 cccgactccc cccggctctc ccaggcgcgc gtctccggca tccgccctca cgctcgcccg
    21121 ggtcaccccg tcctcatcgc cgtgtcagtc gctcggaacg ccgctcgccg ccccggcacg
    21181 gccgagcgtc cggcgcagcc tggggatggc cgccggccgc accggcccgc tcgccggctc
    21241 gggcagaaac tccgccaatc cggcgatggt gggatgctcg aagaccaccc gcagcggtag
    21301 cgacgctccg gtgagcgcgt tgaggcggct gaccagccgc gtggccagca gggaatgccc
    21361 acccagactg aagaagtcgt cgtggatgtt cgtgacgggc cggcccagca ggccggcgaa
    21421 caactcggcc accagatgct gcgcctcggt gccgggaggc tcggccgcgc cggtgctggg
    21481 caccgatgtc ggctcgggta gcgccttgcg gtcgaccttc ccgttggggg tgcgcggcag
    21541 cgcgtccatc accacgatgc gggcagggac cagatgctgc ggcaggcagc tccgcagata
    21601 ccgcaggagg atctgctcgt cgtcctcccc acgctcttcc ggcacgacgg ggtcgtcctg
    21661 ggaggggatc ctggtggcga tgtgggcgat caggtggtcg ccgtggacgg tgacgacggc
    21721 ctccgacacg gcgggatgct ggagcagggc gtgttccacc tcgcccggtt cgatccggaa
    21781 cccccggagc ttcacctggt gatccacccg gccgtggtag tccaggaaga actccacccc
    21841 accgtccgcg gtggtgcagg ggcgccagcg ggccagatcc cccgtccgat acaaccgccc
    21901 accctcaccc tcagggaggg gcaggtagcg ttcggccgtc agccctggcc gctggtggta
    21961 gccccgtgtc acgccctggc ccgataggta cacctcgccg atcgcgccga gcggtaccgg
    22021 tcgcaggtcg ctgtccagca ggtgcacgcg tgatccgggc agggcgcggc ccagcggggt
    22081 ccgctcagca ccgggatcgg tcaccgcgtg ggtggagtac gtggtgtcct cggtcggccc
    22141 gtacaggttg ttgacca
//
