LOCUS       NZ_VANP01000008        22471 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold8, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000008
VERSION     NZ_VANP01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 395720)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 395720)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 288709
            Orig. end                         :: 311180
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22471
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22471
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22471
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12471](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12471)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(85..993)
                     /locus_tag="FED44_RS22115"
                     /old_locus_tag="FED44_22120"
     CDS             complement(85..993)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="FED44_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22120"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_138461899.1"
                     /transl_table=11
                     /translation="MTESVVVRTATEADVPGLRAVANHFRLLGRWPVRPDFLDAERDFG
                     AVVVGEVNGTIAGFGATLPRGKITHLGDLFVLPDRQSSGAGRMILARLLPSGAPMMTFA
                     SADLRALALYVRFGMRPRCPLLYLSRPGSGRGSARPSQSRPSQNGRAARAGSEAPMGAA
                     LAGPESDRFAPGARDVDAAVALDARISGGERAATLGWFAGLPGVTVRAAASGYAFVRVA
                     GDKAVIGPAGGDTPQDCVEAVLEAADACSGADSVEIAVPGTHPLLPLLLDAGWRIDDQD
                     TLMTSEDFLRLDCYVPHPDLG"
     misc_feature    1018..1033
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.79"
                     /tool="antismash"
     misc_feature    1019..1037
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 25.87"
                     /tool="antismash"
     gene            1112..2806
                     /locus_tag="FED44_RS22120"
                     /old_locus_tag="FED44_22125"
     CDS             1112..2806
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024629.4"
                     /locus_tag="FED44_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22125"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_138461900.1"
                     /transl_table=11
                     /translation="MRIRHHAGARPGRSARDAALPAVPALAALLACLWGIRRGSMWQDE
                     ATTYVVAGRPLPDLWRTLGNVDAVHGCYYLLLHPLLGLVGDAVPAEVAIRIPSVLATAV
                     AASGVAAIGRRLVSAPAGLYAGLVYGTAPAVVAYGQEGRSYALVGAAVVEATRLLTRAL
                     EDPARTRRWIWYAVAVAVACLLNLFAALALVAHAATVSIGARGRTAGDEVPGENAGVPD
                     GPRRWGVPLQWAGASACALLAVLPLAWIAFGQRDQVSWLERPGWPEVRALVARFAGSGL
                     SLAATVVLVLLGLTLGLVPGLTPGLTPGLTPGLGDRRANAVGLVAVAVPLAVLPPALLI
                     AVSRIHPFYQDRYVLFSMAGLALLTGAGLARAVKLVPGRAPERSPSQSPRQSPGRSPGG
                     WRGWWRIAPRAAAAVALPVLLLAASLPDQAAVRRIDSRPDDPAAAARVVGSGRRPGDAV
                     LFLPSIRRLVAEAYPASFDGVRDAAIRAGGAESGTLAGRELPAGDLVAALGAAPRVWVV
                     SRPHPAPADLASARDTAKRDLLREGYRKERAFRVLGYTVRLYTRLSP"
     gene            complement(2796..3653)
                     /locus_tag="FED44_RS22125"
                     /old_locus_tag="FED44_22130"
     CDS             complement(2796..3653)
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133472.1"
                     /locus_tag="FED44_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22130"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_117409740.1"
                     /transl_table=11
                     /translation="MSTNRHKQSPASGGLLRSLSLHTIVVITALFVAVPLVYAVLGGFK
                     TTRQLSSNPIGLPDPWMPENYGGILASGSFWHMLWNSTYIAVLTTLVVVAVSALAAFVF
                     ARFAFRGREALFTMFAAGLMFPFAVAILPLFVLLRMFGLLDNPLGVILPQAAFGMPMTI
                     IILRGFFRAIPGEIEEAAILDGCTPFGFFWRILLPMARPAIATVSVLAVVNSWNQFMLP
                     LVVFSDDGLFTIPLGVQQFQGQYATDVARVMAYIVVAMLPALGFYAVAERQLVSGLTAG
                     AVKG"
     gene            complement(3650..4576)
                     /locus_tag="FED44_RS22130"
                     /old_locus_tag="FED44_22135"
     CDS             complement(3650..4576)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133473.1"
                     /locus_tag="FED44_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22135"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_117409739.1"
                     /transl_table=11
                     /translation="MKTTRPRSRRLRGFTTILLFLLPALVLFFGLVVAPILLAFYASVF
                     KWNGMRGLPTDFVGLANFTRLLADEVFLGDLWRGLLLIILSLVVQLPLSLGIAMLLNQR
                     IRGRAFFRLLFFAPYMLSEAITAVLFMMILSPTDGLANVVLGWFGVDPLDWFADPSSVM
                     MSVFIVMTWKYFGFHMILYIAGRQGIPRELTEAAQIDGATGWKVFRYVTLPLLGPTIRI
                     SVFLSVIGAIQLFDLVWIITGGGPSHSSETMAVTMFQFGFKRFQVGYASAISVVMFFIS
                     LVFALFYQRYVMRRDLQGASTVLREQR"
     gene            complement(4584..5870)
                     /locus_tag="FED44_RS22135"
                     /old_locus_tag="FED44_22140"
     CDS             complement(4584..5870)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133474.1"
                     /locus_tag="FED44_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22140"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_117409738.1"
                     /transl_table=11
                     /translation="MNLSRRSAALLAASALVLGGCGSTGNDAGESKSSAEGKVTVEWWN
                     IWTTEPLKSYGAQAIKDFQAKHPNITIKSVPYENEAFKAKLTTLTQSGKAPDVFQTWGG
                     GVLGQQVDAGLVKDLSGDAGSWLGTFTDAALSAYQIEGKTYAIPDDIGMVGFWYNKALF
                     KKAGIAEPPGTWSELIDDVKKLKSAGVTPIALGGKDKWPGHYYWAYLAMRIGGLDALKQ
                     AGASKDFTGAPFVQAGQKLKELADLQPFQKGFLGATYGDPGGQAATMGDGKAAMELMGQ
                     WAPAVEKDAGKGLGDDLGFFPFPAVDGGAGAVTDAFGGGGGFAIGSEAPAEAIEWVKFL
                     TESNEHRKAVATGGVLPVLKGEEDAVTDPNLSVVAKNLAGATGFQLYLDQAYPPAVGQE
                     VNDSVAQLIGGTKTPEQVAQAITETAKSE"
     misc_feature    complement(5862..5864)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    5866..5881
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
     misc_feature    5972..5989
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.06"
                     /tool="antismash"
     gene            complement(6144..6731)
                     /locus_tag="FED44_RS22140"
                     /old_locus_tag="FED44_22145"
     CDS             complement(6144..6731)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854126.1"
                     /locus_tag="FED44_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22145"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_117409737.1"
                     /transl_table=11
                     /translation="MVSGRSDTLKMPKAIKLLIAGGFGVGKTTMVGAVSEIRPLRTEET
                     LTNLSVGVDDLSGVEAKATTTVAMDFGRISIGQDFVLYLFGTPGQERFWFVWDELARGA
                     LGAVVLADTRRLADCFPSVDYFERRGTPFVVAVNCFDGAPVFDLDEVKLALNLGQDVPI
                     LLCDARKRESGKEVLIALVKHAYGRRPTAAAH"
     gene            complement(6712..7086)
                     /locus_tag="FED44_RS22145"
                     /old_locus_tag="FED44_22150"
     CDS             complement(6712..7086)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133476.1"
                     /locus_tag="FED44_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22150"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_117409736.1"
                     /transl_table=11
                     /translation="MNLDWSPDEERLLDAPTIRPYVIARGRTEAQDRFDLISLAVTIRP
                     TTGAEIGLDPEHQAIVRLCRRAMSVAEIAAHLDLPAGIVRVLLGDLFDRGFVAVQQPQP
                     EMDVLDERMYKAVLDGLRAL"
     misc_feature    complement(7051..7053)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7083..7517)
                     /locus_tag="FED44_RS22150"
                     /old_locus_tag="FED44_22155"
     CDS             complement(7083..7517)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854124.1"
                     /locus_tag="FED44_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22155"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_117409735.1"
                     /transl_table=11
                     /translation="MTQKTGASADLAWLLDDLVARVREVEHGIVLSTDGLLLATSQGLR
                     LEDAEHLSAVASGLQSLARGVGERFKGGQVRQTIVEMKSAFLMVTVAGQGACLAVLCTG
                     DADVGLVAYEMAMLVARVGQYLTSPARTTIDRATGREVRL"
     gene            complement(7514..9796)
                     /locus_tag="FED44_RS22155"
                     /old_locus_tag="FED44_22160"
     CDS             complement(7514..9796)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013133478.1"
                     /locus_tag="FED44_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22160"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_117409734.1"
                     /transl_table=11
                     /translation="MRFRNSSVRTKVTALLLSLVALWAFAAWVTLREGLNLVWVAVYDS
                     GVAQPSETLLVELQRERRLTVVAMGNPSADRGNLRAQRARTDAAADEFRRLAKGGNVQF
                     AADAVLKRRIDEMIRQLDGLPKNRSLVDGGQSDRSRAYDSYTTVVDSVYRTYDALATLD
                     DKDVAHDTRTLIDLSRARELLSEEDALLAGALASGRLTVSERARFTEIVGVQRFHKAEA
                     VIALPDSDRAIFERLERGQSFTRLRALEENVMQSSRPGGLPPIGAEQWRAATEPALAEL
                     QSAILEAGDRLVERTTPVAAAVIARLLLAGVLGLVAVVASIVLSVTTARALVRQLEKLR
                     EAALELANERLPGVVSRLAQGEKVDIRAEAPPLDFGPDVIGQVGAAFNTVQETAIRTAV
                     EEAQLRQSIRDILLSLARRTQSLVHRQLTLLDVMERRESDPAELKDLFRIDHLATRMRR
                     NAENLIVLSGASPARAWRRSVPMVDVVRGALAEVEDYTRVTVLPMGQTALNGRAVGDVI
                     HLLAELIENAVSFSPPYTMVQVGGQVVASGYALEIEDRGLGMSPDDLETANQRIADPPE
                     FNLSSTARLGLYVVSRLAERHGIRVSLKASPYGGTTAVVLLPRELVMESGDEHPEQETR
                     PRLDRRERGAREIALVGAPDADPLPVQEVVPVPRAAETPRPAPIAAEPAGPEPPAAFTP
                     SGLPFRVPQASLAPALAEEPKGGAEPEDEEDRSPEDVRKIMGSFQSGTRRGRSEAAKLL
                     GEGEDNL"
     misc_feature    9966..9980
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.3"
                     /tool="antismash"
     gene            complement(10001..11566)
                     /locus_tag="FED44_RS22160"
                     /old_locus_tag="FED44_22165"
     CDS             complement(10001..11566)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632368.1"
                     /locus_tag="FED44_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22165"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_244302138.1"
                     /sec_met_domain="T2TS (E-value: 1.4e-85, bitscore: 282.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDLAPPPATDVVGAAQDLVLGLMSMPWGQVSPSVYETGRLVTLA
                     PWLTGHGERVRWLLGNQRPDGGWGAPDGYGLVPSLSATEALLSVLGRGEDTGVLVEALR
                     EAAARGLRRLSRCLGDPRLSLPDMPAIELIVPSLVARINDHLAANGMSAALALPAGMSE
                     APLAAVRRWVASEEEIPQKLLHALEIAGDAAHGAAAVHVTEIGTVGASPAASAAWLGDR
                     GPSEPGHPVRWHLEAVVRRHGGPVPVGLPITVFERGWVLSSLARAGISFEVPPEMLVDL
                     RTAIGPAGTPAGAGLPPDADTTSVALYALTLLGLPQDPGSLWAFETPTHFCTWQGEEGA
                     SVSVNAHVLDAFGRYAAVRPEAAPAYAPAIRKLSGWLREQQRQDGSWDDRWHASPYYGT
                     ASCGLALHEFGGVEAADAVRAGVEWVLDTQRDDGGWGRWAGTVEETAYALQLLLFAGSG
                     RRVTEAAARGYAYLLRSADVSEGPPLWHDKDLYRPLAVVRAAVLAAMHLAQSRSLVVRL
                     AGQV"
     gene            complement(11569..12471)
                     /locus_tag="FED44_RS22165"
                     /old_locus_tag="FED44_22170"
     CDS             complement(11569..12471)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889881.1"
                     /locus_tag="FED44_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22170"
                     /product="terpene synthase family protein"
                     /protein_id="WP_138461901.1"
                     /sec_met_domain="T1TS (E-value: 4.8e-11, bitscore: 37.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPRPDAGQPASVAASGRTCALAARCQRDLQECAAAFPELFAA
                     RPFDATLYASVSLANAFGSPDATAERLRIANRTSLWIFAADWLIDHEATSRTEIDDIVR
                     GALAVADDRAPDPDTPLTRFLAVIRDELAGSPLFPPLRAAWRDELERMLTAMAREWDWK
                     HQVSGGDSMPSFEQYLGNAGNFGSTFVNVSHWIHAGDPGVVPRLDELTEASDAVQRVLR
                     LLNDLATYERDVTWGDLNALLLGVTRDEVVAHIGILTKECRERLRSLRSGRPDESAYLE
                     RQIGYSTGFYGLADYWGEL"
     gene            complement(12468..13739)
                     /locus_tag="FED44_RS22170"
                     /old_locus_tag="FED44_22175"
     CDS             complement(12468..13739)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="FED44_RS22170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22175"
                     /product="cytochrome P450"
                     /protein_id="WP_208759119.1"
                     /sec_met_domain="p450 (E-value: 1.4e-66, bitscore: 219.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARQARGEVVRLNLGPFRPYLVSHPDHVQHVLRGDWENHPREGVF
                     WKPVERLAGRSILTEGPDWESSRRILQPLFTARYVASLAQDMAETIDKELTAWEAYARE
                     GRWIDICEELARLVSRIVIRVLFGDKISVADAERLAPAYAIAATSFTSRLLVPFAPEWF
                     PMPGDRAFRRAVEVIDDVVLPLVRQARRDPGDGNDIISALARARADEDGPAAERRIRDD
                     LVSIYGASGETTAVALTWLWPLLHDHPEVAARLYEEVEIVVGRGPVDASCLPRLTYLKS
                     VFQEMLRLYPPGWMMPRMALRANLLGDVPIEPGSTLLISPYVTQRLEEFWDRPDEFDPE
                     RFAVDRRERRHRYAYFPFGGGPHLCIGQHLFYMEAPLIVAGILARFRPQVRAPRPLTPF
                     PGASMRPRETVEVRLEPVAGGAGA"
     misc_feature    13951..13964
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.67"
                     /tool="antismash"
     gene            14494..15636
                     /locus_tag="FED44_RS22175"
                     /old_locus_tag="FED44_22180"
     CDS             14494..15636
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544469.1"
                     /locus_tag="FED44_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22180"
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_138461902.1"
                     /transl_table=11
                     /translation="MSKRSAALAALLVVLGLLVTRPAQAAPVRIMTLGDSITGSPGCWR
                     ALLWNRLQSNGFTNIDMVGTLPPQGCSVAYDGDNEGHGGALVTNVADQNQLPGWLSATR
                     PDIVLMHFGTNDVWSNKPTATVLAAYGKLVDQMRAGNPNMRVLVAKIIPMNPGTCPECG
                     QRVVDLNNAIPGWAAAKTTAASPIQVVDQWTGFSTSADTYDGVHPNASGDQKMADRWYP
                     ALAALLGGGQPSPSASPSPSPSPSPSASPSRSPSPSPSPSASPSQSPSQSPSARPSSSG
                     CAASYVVTNQWGGGFQAEVTVKNTGTAPISGWTVTWTFANGQQVSQAWNGTVTQSGANV
                     TAKNVSWNGSLAAGATTTLGFLASWNGVNSAPAPGCVAIP"
     gene            15879..18083
                     /locus_tag="FED44_RS22180"
                     /old_locus_tag="FED44_22185"
     CDS             15879..18083
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024488.4"
                     /locus_tag="FED44_RS22180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22185"
                     /product="sialidase family protein"
                     /protein_id="WP_138461903.1"
                     /transl_table=11
                     /translation="MAQSDRSWPDIDVVGAAVRNPVTVDGRVDGRVEGPAPGELPHEGN
                     RVPDIAALDARRLVVAWRAGVADAHDPSPTDQGAIMYGRSGDAGRTWTIGTLAADTSEH
                     RYHYVMFLKDGGTLLALLGRITIGADRDAAGNVDGFPVTMVAKKSTDGGRTWTGFPVSV
                     AVPANTRGVVVAGKPLRHDGLWLVPYWQAAGGTTRAGVLRSADLVTWTPGALAANPPGL
                     SVEEPQVVVAQDDPGTLLMVARTIRGGTAADKDAYYRSHAAYAATATSVDGGLTWSAFT
                     VDPELPNYYVKTFFTGDSDGRYLTIYNTLAGPFTGPASGKPDQYREVLHYKVKLPGTPW
                     GPGRLFADGRRLTSGAARGWDVYASADEYEPGRFFVVWEHNQIEIRAARLDLPEVFTGI
                     APGWIGWTRSGGVTVPDPAGALRLAAGRISRPYGPPGGFVLTFHGRVTRFPASGEGLRI
                     EVNTGTRLLTAVVRPGGPQVLTAQGPVPVPGADDRWRLIVDATGTVVAQSLPSASPTAS
                     RWALPASSGPRSVSVRSDGEAVLDLLEVTDHVAGGSWQGWRLDPAGGASLLDGGLRLRS
                     TTSRVAAATLPLDVTTACDFTLEFHGRVIDDSALDPRTGQGVALGCKVANGARRLMLTV
                     QRSGVWTMKKGSGTWEKVVSLTGAGRPATWRVAVDSAGVARLSRDGVDTGAAWVVPDSR
                     EAPQVTHWVAGTAGGNAAVAHVDWTLVTATLGGSAATDIR"
     gene            complement(18067..18981)
                     /locus_tag="FED44_RS22185"
                     /old_locus_tag="FED44_22190"
     CDS             complement(18067..18981)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890631.1"
                     /locus_tag="FED44_RS22185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22190"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_138461904.1"
                     /transl_table=11
                     /translation="MTGSLEGKVALVAGATRGAGRGIAVELGAAGATVYVTGRTTRERR
                     SEMNRPETIEETAELVTAAGGRGIAVPVDHLDHDQVQALVKRIDAEQGGLDVLVNDIWG
                     GELLFSWSDRLWEHSLDDGLRILRLAVDTHIVTSHYALPLLIRRPGGLVVEVTDGTAEY
                     NAANYRVSFFYDLAKTSVLRMAFVQAKELAPYGAAAVSLTPGWLRSEIMLEHFGVTEAT
                     WRDALVREPHFAISETPAFVGRAVAALAADPEVSRWNGQSLSSGGLAQVYGFTDVDGSR
                     PDAWRYMVEVQDAGRPADVTGYR"
     gene            19089..19292
                     /locus_tag="FED44_RS22190"
                     /old_locus_tag="FED44_22195"
     CDS             19089..19292
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017536936.1"
                     /locus_tag="FED44_RS22190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22195"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_117410479.1"
                     /transl_table=11
                     /translation="MSEYAATFNLIDTDQDGRISAAELVRLMEVLGQPLTPEGAQGAIN
                     KVDADGDGLIDLDEFATWLSGR"
     gene            19385..20038
                     /locus_tag="FED44_RS22195"
                     /old_locus_tag="FED44_22200"
     CDS             19385..20038
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895192.1"
                     /locus_tag="FED44_RS22195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22200"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_244302139.1"
                     /transl_table=11
                     /translation="MMAAESAQTLERGLRLLRLLADANRGRTPTELAQELGLSRPIVYR
                     LLTTLQAEGFARRDANGRVHLGFGVLVLAQAVHPLLRAAALPELRALAEHAGATAHLTV
                     AEGDEGLAVAVVEPSWTDLHVAYREGSRHPLTRGAGGRALLALREGLAEPPLYTSRGQL
                     QEGAQGIAAPIRGLPWLEASVGVISFADLDAEKVGPLVLDAAARLTTALTEPPR"
     misc_feature    19424..19426
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            20181..21353
                     /locus_tag="FED44_RS22200"
                     /old_locus_tag="FED44_22205"
     CDS             20181..21353
                     /EC_number="1.13.11.5"
                     /GO_function="GO:0004411 - homogentisate 1,2-dioxygenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006570 - tyrosine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654399.1"
                     /locus_tag="FED44_RS22200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22205"
                     /product="homogentisate 1,2-dioxygenase domain-containing
                     protein"
                     /protein_id="WP_117410477.1"
                     /transl_table=11
                     /translation="MPYYRVVGEVPRKRHVQFRAPGGGLYKEELMGEEGFSSDSSLLYH
                     RHAPTAIVKAEAVDAGTPALTPNLPLSPRHFRTQDLKPGGDLVSGRLPLAGNSDVRISY
                     AACDAPSELYRDSMGDECVYVASGRARFESAYGALDVTEGDYVVVPTGTVHRWVPEGPV
                     TALVIEAAGHIRPPKRYLSQYGQFLEHAPYCERDLRAPAEPLLVDGEEVPVLVRTRGGL
                     TRLTYANHPFDVVGWDGCLYPYAFNIRDFEPIVKRTHAPPPVHQTFEGPGFVVCSFCPR
                     PLDFHPEAVPIPYNHHNVDSDEFMFYVGGDYTARKGSGIDVGSISLHPAGFTHGPQPGA
                     VEAAVEAVRQGHTETTEMAVMIDTFRPLDLGQAALACEDTGYAWTWAARR"
     gene            21350..22441
                     /gene="fahA"
                     /locus_tag="FED44_RS22205"
                     /old_locus_tag="FED44_22210"
     CDS             21350..22441
                     /EC_number="3.7.1.2"
                     /GO_function="GO:0004334 - fumarylacetoacetase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006559 - L-phenylalanine catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006572 - tyrosine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fahA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895207.1"
                     /locus_tag="FED44_RS22205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_22210"
                     /product="fumarylacetoacetase"
                     /protein_id="WP_138461967.1"
                     /transl_table=11
                     /translation="MSFGLGNLPYGVFSRAGEPRRVGVRVGDHVLDLAAALGRDVFAAP
                     SLNPFLALGRTAWQEARGRAREAAAAGDHLIPLTEVTLHLPVEVADYVDFYASLEHASN
                     LGRILRPGEEPLKPNWRHLPVGYHGRAGSVVVSGTPIRRPCGQRPSFGPSARLDIEAEL
                     GFVVGVPAPLGGRAGAFEDHVFGVALVNDWSARDIQAWEYVPLGPFLGKSFATSMSAWI
                     TPLEALEEARVEGRSQDPEPLPYLTRQTPWGLDLTLRIDLNGETVSTPSYRDMYWTPDQ
                     MLAHLTVNGAGLRTGDLFASGTVSSAGQPGSLIELTWNGAEPVKLPDETRTFLEDGDTV
                     TITAWTSHGMSLGEVSGTILPAT"
ORIGIN
        1 aggccgggtg tcccgccccc ggctcgccgc cggggcagga cgcccacgcc cgttccgaac
       61 cgatcgcggt gccgctcagg ctggtcagcc gaggtcgggg tgcgggacgt agcagtcgag
      121 acggagaaag tcctcgctgg tcatcagcgt gtcctggtcg tcgatgcgcc atccggcgtc
      181 gagcagcagg ggcagcagcg gatgtgtgcc cggcaccgcg atctcgacgg agtccgcgcc
      241 cgagcaggcg tcggccgcct ccagcaccgc ttcgacgcag tcctgggggg tgtcgcctcc
      301 ggcgggcccg atgacggcct tgtcaccggc cacccgcacg aacgcgtacc ccgaggcggc
      361 ggcccgcacc gtcacgccgg gcaggcccgc gaaccagccg agggtcgcgg cccgctcccc
      421 gccggagatc cgggcgtcca gagccaccgc cgcgtccacg tcgcgggctc ccggcgcgaa
      481 ccggtcgctc tccgggcccg cgagggcggc ccccatggga gcctcgctcc ccgcccgtgc
      541 cgcccgtccg ttctgtgagg ggcggctctg tgacgggcgt gcgctcccgc gtccgctccc
      601 cgggcggctg aggtagagca gggggcatcg gggtcgcatg ccgaaccgga cgtacagggc
      661 gagcgccctg aggtcggccg aggcgaacgt catcatgggg gcgccggacg gcagcagccg
      721 cgccaggatc atccggcccg ctcccgacga ctggcggtcc ggcaggacga acagatctcc
      781 gaggtgcgtg atcttccccc ggggcagggt cgcgccgaag cccgcgatcg tgccgttcac
      841 ctcgccgacg accacggcgc cgaagtcgcg ctccgcgtcc aggaagtccg gccgcaccgg
      901 ccaccggccg agaagccgga agtggttcgc gacggcgcgc agtccgggaa cgtctgcctc
      961 tgtcgcggta cggacgacga cggactccgt catcggtgtc tctccctacg agttttcctc
     1021 acgttcggtt caccttaggc cccgttcccc ttcccgttgc ccttcggggc atcgggtggg
     1081 acgcgaacca gccagacgac acggaggacg tgtgaggatc aggcaccacg ccggcgcccg
     1141 ccccgggcgg agcgctcgcg acgcggccct gccggccgtc ccggccctgg ccgcgctgct
     1201 cgcctgtctg tggggcatcc ggcgtgggtc gatgtggcag gacgaggcga cgacgtacgt
     1261 cgtcgcggga aggccgctgc ccgacctctg gcgcacgctg gggaacgtcg acgcggtgca
     1321 cggctgctac tacctgctgc tccatcctct tctcgggctc gtgggcgacg ccgtcccggc
     1381 ggaggtcgcg atccggattc cctccgtcct cgccacggcc gtcgcggcgt ccggcgtcgc
     1441 ggcgatcgga cggcggctgg tctccgcccc ggccggcctc tacgcgggcc tcgtgtacgg
     1501 cacggccccc gccgtcgtcg cctacggcca ggagggccgg tcgtacgcgc tggtcggggc
     1561 cgctgtggtg gaggccacgc gcctgctcac gcgggcgctg gaggacccgg cgcgcacgag
     1621 gagatggatc tggtacgccg tcgcggtggc ggtggcgtgc ctgctcaacc tcttcgccgc
     1681 cctggcactc gtggcgcacg cggccacggt ttcgatcggc gcccgcgggc ggaccgcggg
     1741 agacgaggtg ccgggcgaga acgccggtgt ccctgacggg ccgcggcggt ggggtgtgcc
     1801 gctccagtgg gccggagcga gcgcgtgcgc cctgctcgcc gtcctgcccc tcgcgtggat
     1861 cgcgttcggg cagcgcgacc aggtctcatg gctggagcgg cccggctggc ccgaggtgcg
     1921 cgctctcgtg gcgcggttcg ccgggtccgg cctctcgctc gcggcgaccg tcgtgctcgt
     1981 cctgctggga ctgacactgg gactcgtacc ggggctgaca ccgggactga caccgggact
     2041 gacaccgggg ctgggcgacc gacgcgccaa cgccgtgggg ctcgtggcgg ttgccgtgcc
     2101 gctcgccgtg ctgccgcccg ccctgctgat cgccgtctcg cggatccacc ccttctacca
     2161 ggaccgctac gtcctgttct cgatggcggg gctcgcgctg ctgacgggcg cggggctggc
     2221 ccgggccgta aagctcgtgc ccggacgggc gccggaacgg tcgccgagcc agtcgccaag
     2281 acagtcgcca ggccggtcgc cgggtgggtg gcggggttgg tggcggatcg cgccgcgggc
     2341 agccgccgcg gtggcgctgc cggtgttgct gctggcggcg tccctgccgg accaggccgc
     2401 cgtccggcgg atcgacagcc gcccggacga cccggccgcc gcggcccggg tcgtcgggtc
     2461 gggacggcgg cccggagacg ccgtgctctt cctgccctcg atccgccgcc tggtcgccga
     2521 ggcgtacccc gcctcgttcg acggggtccg cgacgcggcg atcagggccg gcggcgcgga
     2581 gtcgggcacg ctggccggcc gggaactgcc cgcgggcgac ctcgtcgccg cgctgggcgc
     2641 ggcgccccgg gtgtgggtgg tgagccgccc gcatcccgcg cccgccgacc tggcgtccgc
     2701 gcgggacacg gccaagcggg acctgctgcg ggagggctac cggaaggagc gggccttccg
     2761 ggttctcggc tacaccgtac ggctgtacac gcggctcagc ccttgacggc ccccgcggtg
     2821 aggccgctga cgagctgccg ctcggccact gcgtagaaac cgagggcggg cagcatcgcg
     2881 accacgatgt aggccatgac ccgggcgacg tccgtcgcgt actggccctg gaactgctgg
     2941 acgcccagcg ggatcgtgaa caaaccgtcg tcgctgaaca ccaccagcgg cagcatgaac
     3001 tggttccagc tgttgacgac cgccagcacg gacaccgtgg cgatcgcggg ccgggccatc
     3061 gggagcagga tccgccagaa gaagccgaac ggggtgcacc cgtcgaggat cgccgcctcc
     3121 tcgatctctc ccgggatggc ccggaagaag ccgcgcagga tgatgatcgt catcggcatg
     3181 ccgaaggcgg cctgcggaag gatcacgccg agcgggttgt cgagcagccc gaacatccgc
     3241 agcagcacga acagcggcag gatcgccacc gcgaacggga acatgagccc ggcggcgaac
     3301 atcgtgaaca gcgcctcgcg gccacggaag gcgaaccggg cgaacacgaa ggccgccagc
     3361 gccgagaccg cgacgaccac gagcgtggtc agcaccgcga tgtaggtgct gttccagagc
     3421 atgtgccaga acgaccccga ggcgagaatg cccccgtagt tctccggcat ccaggggtcg
     3481 ggcaggccga tcgggttgct ggagagctgc cgggtggtct tgaagccgcc gagcacggcg
     3541 tacaccagcg ggacagcgac gaacaacgcc gtgatcacga cgatcgtgtg cagggacagg
     3601 ctgcgcagga gaccgcccga cgccggcgac tgcttgtggc ggttggtgct catcgctgtt
     3661 ctcgcagcac ggtggaggct ccttggaggt cacgccgcat gacgtatctc tggtagaaga
     3721 gcgcgaacac gaggctgatg aagaacatca ccacgctgat cgcactcgcg tagccgacct
     3781 ggaagcgctt gaaaccgaac tggaacatcg tcacggccat ggtctcggag gagtgcgacg
     3841 ggcctccgcc ggtgatgatc cagaccaggt cgaacagctg gatcgcaccg atgaccgaca
     3901 ggaacacgct gatgcggatg gtggggccga gcagcggcag cgtgacgtag cggaagacct
     3961 tccagccggt cgcgccgtcg atctgggcgg cctcggtgag ctcccgcggg atgccctggc
     4021 gcccggcgat gtacaagatc atgtggaagc cgaagtactt ccaggtcatg acgatgaaca
     4081 ccgacatcat caccgacgac gggtcggcga accagtcgag ggggtcgacc ccgaaccagc
     4141 ccaggacgac gttggccagg ccgtccgtcg gcgaaaggat catcatgaac aggaccgcgg
     4201 tgatcgcctc tgacagcatg tacggggcga agaacagcag gcggaagaag gcccggccgc
     4261 ggatcctctg gttgagcagc atggcgatgc ccagcgagag gggaagctgc accaccagcg
     4321 acaggatgat cagcaacagg ccgcgccaca ggtcgcccag gaagacctcg tccgccagca
     4381 ggcgggtgaa gttcgccagc ccgacgaagt cggtgggcag gccgcgcatg ccgttccact
     4441 tgaagacgct cgcgtagaag gcgagcagga tcggcgccac cacaagcccg aagaagagca
     4501 cgagcgcggg cagcaggaac aggaggatcg tggtgaaccc ccggagccgg cggctccggg
     4561 gtctcgtcgt cttcacgcgg cagttactcc gacttcgccg tttccgtgat ggcctgagcc
     4621 acctgctccg gcgtcttggt tccaccgatc agctgggcca cgctgtcgtt gacctcctgg
     4681 cccacggccg gcgggtacgc ctggtcgagg tagagctgga acccggtcgc cccggcgagg
     4741 ttcttggcga ccacgctcag gttcgggtcg gtgaccgcgt cctcctcgcc cttcagcacc
     4801 gggagcacgc cgccggtcgc gacggccttg cggtgctcgt tgctctcggt gaggaacttc
     4861 acccactcga tcgcctcggc cggcgcctcg gagccgatcg cgaagccgcc accgccgccg
     4921 aaggcgtcgg tgaccgcgcc ggcgccgccg tcgacggccg ggaaggggaa gaagccgagg
     4981 tcgtcgccga gtcccttgcc ggcgtccttc tcgaccgcgg gcgcccactg gcccatcagc
     5041 tccatcgcgg ccttgccgtc gcccatggtc gcggcctggc cgcccgggtc gccgtaggtc
     5101 gcgccgagga agcccttctg gaacggctgg aggtccgcga gctccttgag cttctgcccc
     5161 gcctgcacga aaggcgcgcc cgtgaagtcc ttgctcgcac ccgcctgctt cagcgcgtcg
     5221 aggccgccga tccgcatggc gaggtaggcc cagtagtagt ggcccggcca cttgtccttg
     5281 ccgcccaggg cgatcggggt gacgccggcc gacttgagct tcttgacgtc gtcgatgagc
     5341 tccgaccagg tccccggcgg ctcggcgatc ccggccttct tgaacagggc cttgttgtac
     5401 cagaagccga ccatgccgat gtcgtccggt atcgcgtacg tcttgccctc gatctggtac
     5461 gccgacagcg ccgcgtcggt gaacgtgccg agccaggaac cggcgtcgcc ggagaggtcc
     5521 ttgaccaggc ccgcgtcgac ctgctggccg agcacgccac cgccccaggt ctggaagacg
     5581 tccggcgcct tgccggactg cgtgagcgtc gtcagcttcg ccttgaacgc ctcgttctca
     5641 tagggaacgc tcttgatggt gatgttcggg tgcttggcct ggaaatcctt gatcgcctga
     5701 gcgccgtagc tcttcaatgg ctcggtggtc cagatgttcc accactcgac cgtcaccttg
     5761 ccctcggctg agctcttgct ctcgccggca tcgttcccgg tactaccgca tcccccgagg
     5821 acaagcgcgg acgccgccag cagcgccgca ctccgacgac ttaaattcac ggtggtttcc
     5881 cttctggatt ccaaccgaaa ctttcggaat tcagaccgat agtttctgcg atggggcaga
     5941 ggctacagcg ggctcacgct catatcaacg gctgttgtgc agctgttacg agccgccgga
     6001 ggcgaaagaa aggcatgttc gccgctctaa tcacaaaagg gttataaagg aataaatcag
     6061 tccttagtgc acgaacctct caagtcactt gaaaacggaa ggaggccgtg tggggacacg
     6121 gcctcctgaa gacgcgggac gcgtcagtgc gcggcggcgg tcggccgccg gccgtacgcg
     6181 tgcttgacga gcgcgatcag gacctccttg cccgactccc gcttgcgcgc gtcgcacagc
     6241 aggatcggca cgtcctggcc gaggttcagc gcgagcttga cctcgtccag gtcgaagacc
     6301 ggtgcgccgt cgaagcagtt caccgcgacg acgaaggggg tgccgcgccg ctcgaagtag
     6361 tcgacggagg ggaagcagtc ggccagcctg cgggtgtcgg ccagcaccac cgcgccgagc
     6421 gctccccggg ccagctcgtc ccacacgaac cagaaccgct cctggcccgg ggtgccgaag
     6481 agatagagga cgaagtcctg cccgatgctg atgcggccga aatccatggc cacggtggtg
     6541 gtcgccttcg cctcgacccc ggacaggtcg tccacaccga cgctgaggtt cgtcagcgtc
     6601 tcctcggtgc gcagggggcg gatctccgag accgcgccga ccatcgtcgt cttgccgacc
     6661 ccgaagccgc cggcgatcag cagtttgatc gccttgggca tcttcagggt gtcagagcgc
     6721 ccggagacca tcgagcaccg ccttgtacat ccgctcgtcg agcacgtcca tctccggttg
     6781 gggctgctgc acggccacga acccccggtc gaacaggtcg ccgaggagga cccggacgat
     6841 cccggccggc aggtccaggt gagcggcgat ctccgccacc gacatcgccc ggcggcacag
     6901 ccgtacgatc gcctggtgct cggggtcgag cccgatctcg gctccggtgg tggggcggat
     6961 cgtcaccgcg agcgagatga ggtcgaagcg gtcctgcgcc tccgtacggc cgcgcgcgat
     7021 gacgtacggg cggatcgtcg gcgcgtcgag taagcgttcc tcgtccgggc tccagtcaag
     7081 gttcacaggc ggacctccct gcccgtggcc cggtcgatcg tcgtccgcgc gggcgaggtc
     7141 aggtactgcc cgacacgcgc gacgagcatc gccatctcgt acgccaccag gcccacgtcg
     7201 gcgtcgccgg tgcagagcac ggccaggcag gcgccctgcc ccgccaccgt caccatcagg
     7261 aacgcggact tcatctccac gatggtctgc cgtacctggc cgcccttgaa gcgctcgccg
     7321 acaccgcggg cgaggctctg cagcccggac gccacggcgg agagatgctc ggcgtcctcc
     7381 aggcgcaggc cctgggaggt cgccagcagc agaccgtccg tggacaacac gatgccgtgc
     7441 tccacctcgc ggacccgcgc gacgaggtcg tcgagcagcc acgcgaggtc cgcggacgcg
     7501 ccggtcttct gtgtcacagg ttgtcctccc cttcacctag cagcttggcg gcctcggatc
     7561 tgccgcgcct ggtccccgac tggaacgagc ccatgatctt gcggacgtcc tccggcgagc
     7621 ggtcctcctc gtcctccggt tccgcgccgc ccttcggctc ctcggcgagc gccggagcga
     7681 ggctcgcctg gggcacccgg aacggcagcc cggacggggt gaacgcggcc gggggctcgg
     7741 gcccggccgg ctcggcggcg atcggcgcgg gcctgggcgt ctctgctgcc ctcggcacgg
     7801 gaaccacctc ctggactggt agcgggtccg cgtcgggcgc gcccaccagc gcgatctcgc
     7861 gcgccccgcg ttcccgtcgg tcgagacgag gacgggtctc ctgctcgggg tgttcgtcgc
     7921 cgctctccat gacgagctcg cgcggcagca ggacgaccgc ggtcgtgccg ccgtacggcg
     7981 acgccttgag cgacaccctg atgccgtgcc gctcggcgag acggctgacc acgtacaggc
     8041 ccagcctcgc ggtgctggac aggttgaact cgggcggatc ggcgatccgc tggttggccg
     8101 tctccaggtc gtcggggctc atcccgagac cccggtcctc gatctccagg gcgtacccgc
     8161 tggccaccac ctgaccgccc acctgcacca tcgtgtacgg cggggagaac gacaccgcgt
     8221 tctcgatcag ctccgcgagc aggtggatga cgtcgccgac cgcgcgtccg ttgagcgctg
     8281 tctgccccat gggcagcacg gtgacccggg tgtagtcctc gacctcggcc agggcgccgc
     8341 gcacgacgtc gaccatgggc accgagcgcc gccaggcacg ggcgggggac gccccggaca
     8401 ggacgatgag gttctcggcg ttgcgccgca tgcgggtggc gaggtggtcg atgcggaaca
     8461 ggtccttcag ctccgcgggg tccgactcac gccgctccat cacgtcgagc agggtcagct
     8521 ggcggtggac cagcgactgc gtacgccggg cgaggctcag caggatgtcg cggatgctct
     8581 gcctgagctg cgcctcctcg accgcggtgc ggatcgcggt ctcctgcacg gtgttgaacg
     8641 ccgcgcccac ctggccgatg acgtccgggc cgaagtccag cggcggcgcc tccgcgcgga
     8701 tgtcgacctt ctcgccctgg gcgaggcggg agaccactcc gggcagccgt tcgttggcca
     8761 gctcgagcgc ggcctcccgc agcttctcca gctggcggac cagcgccctg gccgtcgtga
     8821 ccgacaggac gatcgacgcg acgaccgcca ccaggccgag cacaccggcc agcaggagcc
     8881 gggcgatgac ggcggcggcg acgggagtgg tccgctcgac caggcggtca ccggcctcca
     8941 ggatcgcgct ctgcagctcc gccagagcgg gctccgtcgc ggcccgccac tgctccgcgc
     9001 cgatcggcgg aaggccgccc ggccgcgagc tctgcatgac gttctcttcg agcgcacgca
     9061 ggcgggtgaa gctctgtccc cgctccaggc gttcgaagat ggcgcggtcg gagtcgggca
     9121 gcgcgatgac ggcctcggcc ttgtggaagc gctgaacgcc gacgatctcc gtgaacctcg
     9181 cgcgttccga cacggtcagc cgcccggagg cgagggctcc ggcgagcagc gcgtcctcct
     9241 ccgagagcag ttcccgtgcc cggctcaggt cgatgagcgt acgcgtgtcg tgcgcgacgt
     9301 ccttgtcgtc cagggtggcc agcgcgtcgt aggtgcggta gacggagtcg acgacagtcg
     9361 tgtaggagtc gtacgccctg ctgcggtcgg actgtccgcc gtcgacgaga ctgcggttct
     9421 tcggcagccc gtcgagctgg cggatcattt cgtcgatacg ccgcttcagc accgcgtcgg
     9481 cggcgaactg cacgtttccg cccttggcca ggcggcggaa ctcgtcggcc gccgcgtccg
     9541 tccgcgcccg ctgcgcgcgc aggttgccgc ggtcggccga ggggttcccc atggcgacga
     9601 cggtgagccg ccgttcccgc tggagctcga ccaggagcgt ctcgctcggc tgcgccacac
     9661 cactgtcgta gacggcgacc cagaccaggt tgaggccctc ccgtagcgtc acccacgcgg
     9721 cgaacgccca cagcgcgaca agggacaaca gcaaagccgt caccttggtc cgcacgctgg
     9781 aattacggaa gcgcatgaga ccaccctgcg aaatcggcga tacgcgagcg tttcgcggcg
     9841 attaacatcg cccgacgtca aggggtcgca cgcgctgctc acccaaaaac ccgcgctaca
     9901 tctcggacac cttagcaaat gccaagaaaa cccctcaagc cggagcaatg tggtcaataa
     9961 tgtccacttt tccgaaaatg acggatttcc cgagcgttga tcatacttga ccagcgagcc
    10021 tcacaacaag tgatcgagac tgtgcgaggt gcatcgccgc cagaacggcc gcccgcacga
    10081 ccgccagcgg ccgatagaga tccttgtcgt gccacagcgg cggtccctcg gacacgtcgg
    10141 ccgaccgcag caggtaggcg tacccccgcg ccgccgcctc cgtcacccgc cgcccgctgc
    10201 cggcgaacag gaggagttgc agggcgtagg cggtctcctc caccgtaccg gcccagcggc
    10261 cccatccgcc gtcgtcgcgc tgggtgtcca gcacccactc gacaccggcc cgcaccgcgt
    10321 ccgccgcctc cactccgccg aactcgtgca gcgcgaggcc gcaggacgcg gtgccgtagt
    10381 acggcgacgc gtgccaccgg tcgtcccagc tcccgtcctg ccgctgctgt tcgcggagcc
    10441 atccggacag cttgcggatg gccggcgcgt acgccggggc ggcctccggc cgtaccgcgg
    10501 cgtaccgccc gaaggcgtcg agcacgtgag cgttgacact gacggacgcg ccctcttctc
    10561 cctgccaggt gcagaaatgc gtcggcgtct cgaacgccca caggctgccg ggatcctggg
    10621 gcaggccgag cagcgtcaac gcgtacaggg cgacggaggt ggtgtcggcg tcgggcggca
    10681 gccccgcgcc cgccggcgtg cccgccggac cgatcgccgt cctgaggtcc accagcatct
    10741 ccggagggac ctcgaacgat atgccggccc gcgccagcga gctcagcacc catccgcgct
    10801 cgaagacggt gatcggcagg cccaccggca ccgggccgcc gtgccgccgc accaccgcct
    10861 cgaggtgcca gcggacggga tgcccgggct cactgggtcc tctgtcaccc agccatgccg
    10921 cactcgcggc gggcgacgcc ccgaccgtgc cgatctcggt cacgtggacc gcggccgcgc
    10981 cgtgggccgc gtccccggcg atctccagcg cgtgcaggag cttctggggg atctcctcct
    11041 ccgacgccac ccacctgcgg accgccgcca gcggggcctc gctcatcccg gcgggcagcg
    11101 cgagggcggc gctcatcccg ttcgcggcga gatggtcgtt gatgcgcgcg accagcgacg
    11161 ggacgatcag ctcgatggcc ggcatgtcgg gcagcgacag gcgcgggtcg ccgaggcaac
    11221 gggacagccg ccgcaggccc cgcgcggcgg cctcccgcag cgcctccacc agtacgccgg
    11281 tgtcctcgcc ccggcccagc accgaaagga gagcctcggt cgcgctgagg gagggcacca
    11341 gcccgtaacc gtccggggct ccccatcctc cgtccgggcg ctggttgccc agcagccagc
    11401 gcacgcgctc gccgtgcccg gtgagccagg gggccagggt caccaggcgg ccggtctcgt
    11461 agacggacgg ggatacctgt ccccacggca tcgacatcag cccgagcacc aggtcctggg
    11521 ccgcgcccac gacgtcggtc gccggcggcg gggcaaggtc gttcactttc aaagttcgcc
    11581 ccagtagtcc gcgagcccgt agaagcccgt gctgtaaccg atctgccgtt cgagataggc
    11641 cgactcgtcc gggcggccgc tccgcagcga ccggagccgc tcccggcact ccttcgtgag
    11701 gatcccgatg tgcgcgacca cctcgtccct ggtcacgccg agcaggaggg cgttgagatc
    11761 accccaggtg acgtcgcgct cgtaggtggc gaggtcgttc agcagacgca gcacgcgctg
    11821 caccgcgtca ctcgcctcgg tcagctcgtc caggcgggga acgacgccgg ggtctcctgc
    11881 gtggatccag tgcgagacgt tgacgaacgt cgatccgaaa ttcccggcgt tcccgagata
    11941 ctgctcgaag gagggcatcg agtccccgcc ggagacctgg tgcttccaat cccactcgcg
    12001 cgccattgcc gtgagcatcc gttcgagctc gtcccgccag gccgcgcgca gcggtgggaa
    12061 gagcggggac ccggcgagct cgtcgcggat gacggcgagg aaccgcgtga gcggcgtgtc
    12121 cggatcgggc gcgcggtcgt ccgcgaccgc gagcgccccg cgcacgatgt cgtcgatctc
    12181 cgtccgcgag gtggcctcgt gatcgatcaa ccagtcggcc gcgaagatcc acagggatgt
    12241 gcggttggcg atcctcagcc gctcggcggt cgcgtccgga gacccgaacg cgttggccag
    12301 ggacaccgac gcgtacagcg tcgcgtcgaa cggcctggcc gcgaacagct cggggaacgc
    12361 ggcggcgcac tcctggaggt ctcgctgaca gcgcgccgcg agggcgcagg tcctgccact
    12421 tgccgccacc gacgccggct gcccggcgtc gggacgtggt gccgtgctca tgccccggcg
    12481 cctccggcga cgggctcaag gcgcacctcg accgtttccc tgggccgcat cgacgcgccc
    12541 gggaacggcg tgagcggccg gggggcgcgc acctgcggcc ggaaccgcgc caggatgccg
    12601 gccacgatca gcggcgcctc catgtagaag aggtgctggc cgatgcagag atgggggcct
    12661 ccgccgaagg ggaagtaggc gtaccggtgc cgccgctcac gcctgtccac cgcgaaccgc
    12721 tcggggtcga actcgtccgg acggtcccag aactcctcca gccgctgggt cacgtaaggg
    12781 ctgatgagca gggtggaacc gggctcgatc ggcacgtcgc cgaggaggtt ggcccgcagc
    12841 gccatacgcg gcatcatcca gcccggcgga tacagccgga gcatctcctg gaacaccgac
    12901 ttcaggtagg tcagccgggg caggcaggac gcgtccaccg ggccgcgccc gacgacgatc
    12961 tccacctctt cgtacagacg cgcggcgacc tctgggtgat cgtggaggag cggccacagc
    13021 caggtcagcg ccaccgccgt ggtctcgccc gacgcgccgt agatgctgac gaggtcgtcg
    13081 cggatccgcc gttcggcggc cgggccgtcc tcgtcggcac gggcgcgggc gagcgccgag
    13141 atgatgtcgt tgccgtcgcc gggatccctg cgggcctgcc tgaccagcgg cagcaccacg
    13201 tcgtcgatca cctcgaccgc tcgcctgaaa gcccggtctc cgggcatcgg gaaccactcg
    13261 ggcgcgaagg gcaccagcaa ccgggaggtg aacgaggtcg cggcgatcgc gtacgccggg
    13321 gccagccgct cggcgtccgc gacggagatc ttgtcgccga acaggacccg gatgacgatc
    13381 cggctcacca ggcgggccag ctcctcgcag atgtcgatcc agcgcccctc ccgggcgtac
    13441 gcctcccagg ccgtgagctc cttgtcgatc gtctcggcca tgtcctgggc caggctcgcg
    13501 acgtacctgg cggtgaagag gggctgcagg attctccggc tggactccca gtcggggccc
    13561 tcggtgagga tgctccggcc ggccagccgc tccaccggct tccagaagac gccctcccgc
    13621 gggtggttct cccagtcgcc gcgcaggacg tgctgtacgt ggtccggatg acttacgagg
    13681 taggggcgga acggacccag gttgagccgg acgacctcgc cgcgcgcctg ccgggccaat
    13741 ccggcgagcg tgtttaccgg gtcacgaagc aggggacgga cggtacggcg caatggcagg
    13801 gataaggatc tcgccggtgg cctgatgtcg atcgcctcgg aagtcacggc cgtctccctc
    13861 tcgcggtagg catgtggccg gacgcccctc gcctgggcct cgtccagtga ccacaccgat
    13921 cgtcactggc ggagtatcac acgccgagga agttttgatc aagattctgg cctagtgata
    13981 cttttgtagg gattcattac cagatagacc atcggggacc ccttggcgtg gttcgggaac
    14041 gccgaaacca ccgcaaccag gcacaacgaa aaagggccgg accatagcgg tccggccctc
    14101 acggctcggc gtcagccgtg gctggtcacc agcagcgcga tgcccacgag gatgacgatg
    14161 gggatcagcc acaccacgac ctcgccgagg aactccttgt acatggggac cgaatcctct
    14221 cggtgacgtg cgaaaaagcg aacggacctg cagcatattc ggtcccgccg ccccggcgga
    14281 acccgcatcg ccccaggcga cggcgggtgc gggccggtcg cggcacccgt cccggccggg
    14341 ccccgttcaa ggtcccgcgc aggatccgga tgcaagatca aaactgaaac gtacatgaaa
    14401 cgtcccaggt aggcccgttc tcccggggcc gtccctgggc cggacgggtc accgctccct
    14461 accatcgcgc cggacggcac gagggagagc ggtatgtcga agagaagcgc ggccctggcg
    14521 gccctgctcg tggtgctcgg gctgctcgtc acccggcccg cgcaggcggc cccggtgcgg
    14581 atcatgacgc tgggcgactc gatcaccgga tcgcccggct gctggcgggc cctgctctgg
    14641 aacaggttgc agagcaacgg cttcaccaac attgacatgg tgggaacgct gcctccccag
    14701 ggctgctcgg tcgcctacga cggcgacaac gagggtcacg gcggcgcgct ggtcaccaac
    14761 gtggccgacc agaaccagct gcccggatgg ctctcggcga cccgtcccga catcgtgctg
    14821 atgcacttcg gcaccaacga cgtgtggagc aacaagccca ccgcgaccgt cctcgcggcg
    14881 tacggcaagc tcgtggacca gatgcgggcc ggcaacccga acatgcgggt gctggtcgcc
    14941 aagatcattc cgatgaaccc gggcacctgc cccgagtgcg ggcagcgggt ggtcgacctg
    15001 aacaacgcca tccccggctg ggccgccgcc aagaccaccg cggcgtcccc gatccaggtg
    15061 gtcgaccagt ggaccggctt cagcacgagc gcggacacct acgacggcgt ccaccccaac
    15121 gcgagcggcg accagaagat ggccgacagg tggtacccgg ccctggcggc gctgctcggc
    15181 ggcggacagc cgtcgccctc cgcgtcgcct tcgccttcgc cttctccctc gccgtccgcg
    15241 tcgccctcac gttcgccctc tccctcgccg tcaccgtccg catcgccgtc gcagtcgccg
    15301 tcccagtcgc cgtcggcccg gcccagttcc tcaggctgcg ccgcctccta tgtggtcacc
    15361 aaccagtggg gcggcggctt ccaggccgaa gtcacggtga agaacaccgg cacggccccc
    15421 atcagcggct ggaccgtgac ctggaccttc gcgaacggcc agcaggtgtc ccaggcgtgg
    15481 aacggcacag tcacccagag cggggcgaac gtgacggcga agaacgtgag ctggaacggc
    15541 tccctcgccg cgggcgccac caccaccctg ggcttcctcg cctcctggaa cggcgtcaac
    15601 tccgctcccg ctccgggctg cgtggccatc ccctgacctc caccgggccc ggccggtcac
    15661 ggcgcggcgg cccgcccggc aggcgcgcgt cccccggcgt cccccggtgc cccgagcggg
    15721 ccccggggga cgcgcgcgaa cggcggcggc acggccccag gcggacggcc ggtcctccgg
    15781 gagcgagccg ggcgggggac gttaccggca gatgcacacg aacttaaaac cccgcgacca
    15841 gccctgccca ccggccgaca aacgtgttcc ctgggacgat ggcgcagtct gaccggtcat
    15901 ggcccgatat cgacgtggtc ggcgccgccg tccgcaaccc cgtcaccgtt gacggccggg
    15961 tggacggccg cgtcgagggc ccggcgccgg gcgagcttcc gcacgagggc aaccgggtgc
    16021 ccgacatcgc cgcgctcgac gcccgccgtc tcgtggtggc ctggcgtgcc ggagtggccg
    16081 acgcgcacga cccctccccc accgaccagg gcgcgatcat gtacggccgc tccggcgacg
    16141 cgggccgcac ctggaccatc ggcacgctcg cggccgacac gtccgagcac cgctaccact
    16201 acgtcatgtt cctcaaggac ggcgggacgc tgctcgcgct cctcggccgg atcaccatcg
    16261 gcgccgaccg cgacgccgcc gggaacgtcg acggcttccc cgtcacgatg gtcgcgaaga
    16321 agagcaccga cggcggccgc acgtggaccg gcttccccgt gtcggtggcc gtgcccgcca
    16381 acaccagagg ggtcgtggtg gccggcaaac cgctgaggca cgacggcctg tggctggtgc
    16441 cgtactggca ggcggcgggg ggcaccacca gggccggcgt gctgcgttcg gcggacctgg
    16501 tcacctggac gcccggcgcc ctcgcggcca acccgcccgg cctgtcggtg gaggaacccc
    16561 aggtcgtggt ggcccaggac gacccgggca cgctgctcat ggtcgcccgc acgatccgcg
    16621 gcggcaccgc ggcggacaag gacgcgtact accgctcgca cgcggcgtac gccgcgaccg
    16681 cgacgagcgt ggacggcggg ctgacctggt ccgccttcac cgtggacccg gaactgccga
    16741 actactacgt caagacgttc ttcaccgggg actccgacgg ccgctacctg acgatctaca
    16801 acacgctggc cgggccgttc accggcccgg cgtccggcaa gcccgaccag taccgcgagg
    16861 tactccacta caaggtcaaa ctgccgggca cgccgtgggg cccgggacgg ctcttcgccg
    16921 acggcaggcg actgacctcg ggggcggccc gcggctggga cgtctacgcc tcggccgacg
    16981 agtacgagcc gggccggttc ttcgtcgtct gggagcacaa ccagatcgag atcagggccg
    17041 cccggctcga cctgccggag gtcttcaccg ggatcgcccc cgggtggatc gggtggaccc
    17101 ggagcggcgg cgtgacggtg ccggaccccg cgggcgcgct gcgcctcgcc gccgggcgga
    17161 tcagccgtcc gtacggaccg ccgggcggtt tcgtcctgac cttccacggc agggtgaccc
    17221 gattccccgc ctcgggcgag ggcctgagga tcgaggtgaa cacgggcacg cgactcctta
    17281 ccgccgttgt ccgtcccggc gggccgcagg tgctgaccgc gcaggggccg gtgcccgtcc
    17341 ccggcgcgga cgaccggtgg cggttgatcg tcgacgccac gggcaccgtg gtcgcgcagt
    17401 ccctcccctc cgcctccccc acggcctccc ggtgggccct ccccgcgtcg tccggcccga
    17461 ggagcgtgtc ggtccggagc gacggagagg ccgtgctcga cctgctggag gtcaccgacc
    17521 atgtggccgg cgggtcctgg cagggctggc ggctcgaccc ggcgggcgga gcgtcgctcc
    17581 tggacggcgg cctgcgcctg cgcagcacca cgagccgggt cgcggcggcc acgctgccgc
    17641 tcgacgtgac cacggcctgc gacttcactc tggagttcca cggccgggtg atcgacgaca
    17701 gcgccctgga tccccgcacc ggacaggggg tcgctctcgg ctgcaaggtc gccaacggcg
    17761 cccggcggct catgctgacg gtgcagcgga gcggtgtgtg gacgatgaag aagggctccg
    17821 gcacctggga gaaggtcgtc tcgctcaccg gcgccgggcg gccggccacc tggagggtcg
    17881 ccgtggacag cgcgggagtg gcccggctgt cccgcgacgg cgtcgacacc ggggcggcct
    17941 gggtcgtgcc ggacagcagg gaggcgccgc aggtcacgca ttgggtcgcg ggcacggcgg
    18001 gcggcaacgc cgccgtcgcc cacgtcgact ggaccctggt caccgccacc ctcggcggct
    18061 ccgccgctac cgatatccgg tgacgtcggc ggggcggccg gcgtcctgca cctcgaccat
    18121 gtagcgccag gcgtccgggc ggctgccgtc cacgtcggtg aagccgtaca cctgggctag
    18181 ccctccgctg gacaacgact gcccgttcca gcggctcacc tcggggtcgg cggccagggc
    18241 cgcgaccgcg cgccccacga aggccggggt ctcggagatg gcgaagtgcg gctcgcgaac
    18301 cagcgcgtcc cgccaggtcg cctccgtcac gccgaagtgc tccagcatga tctccgagcg
    18361 cagccagccg ggcgtgagcg acaccgccgc cgcgccgtac ggcgccagct ccttggcctg
    18421 cacgaacgcc atgcggagca ccgaggtctt cgcgaggtcg tagaagaacg agacgcggta
    18481 gttggcggcg ttgtactccg ccgtgccgtc ggtcacctcc acgaccagcc cgcccggcct
    18541 gcggatcagc aggggcagcg cgtagtgact ggtgacgatg tgcgtgtcga cggcgagccg
    18601 caggatgcgc aggccgtcgt cgagggagtg ctcccagagc cggtcgctcc agctgaacag
    18661 cagctccccg ccccagatgt cgttgaccag cacgtcgagc ccgccctgct cggcgtcgat
    18721 ccgcttcacc agggcctgca cctggtcgtg gtcgagatgg tcgaccggca ccgcgatccc
    18781 ccgccctccg gcggcggtga ccagctcggc cgtctcctcg atcgtctccg ggcggttcat
    18841 ctccgaacgc cgctcacgcg tggtgcggcc ggtcacgtac accgtcgcac ccgccgcgcc
    18901 cagctccacc gcgatgccgc ggcccgcacc gcgggtcgcc ccggcgacca gagcgacctt
    18961 cccctccagg cttcccgtca tgggtcgtca tgctgccaga cgccaccgac gaaaagtgtt
    19021 ggccgcgatc cctgtgggca gtgcgtgctt tcggttaggg tgctgatcgc gatcccgagg
    19081 aggacggcat gagcgaatac gcggcgactt tcaacctgat cgacaccgac caggacggac
    19141 ggatctcggc cgcggaactc gtccgcctga tggaggtgct cgggcagccg ctcacgcccg
    19201 agggcgcaca gggggcgatc aacaaggtcg acgcggacgg cgacggcctg atcgacctcg
    19261 acgagttcgc cacctggctc agcggacgct gagccggcgc cgggaggaca cccgggcggc
    19321 ggcgcacccc tgaagagccg cgaagcgcgc cgctccaggg tgccggggcg gcgataatcg
    19381 agtcatgatg gcggccgagt cggcgcagac gctcgaacgg ggcttacggc tgttgcggct
    19441 gctcgccgac gccaaccggg ggcggacgcc caccgagctg gcccaggagc tgggcctcag
    19501 ccggccgatc gtctaccggc tgctgacgac gctgcaggcg gaggggttcg cccggcggga
    19561 cgcgaacggc cgggtgcatc tgggcttcgg cgtgctggtc ctggcccagg ccgtgcatcc
    19621 gctgctgcgg gcggcggccc tgccggagct gcgcgcgctc gccgagcacg cgggggcgac
    19681 cgcccacctg accgtggccg agggcgacga agggctcgcg gtcgcagtgg tcgagccctc
    19741 gtggaccgat ctccacgtcg cctaccgcga gggatcgcgc caccccctga cgcgcggcgc
    19801 gggcgggcgg gcgctgctcg cgctgaggga gggcctcgcg gagccgccgc tgtacacgag
    19861 cagggggcag ctccaggagg gggcgcaggg catcgccgcc ccgatccggg gtcttccctg
    19921 gctggaggcg tcggtcgggg tgatcagctt cgccgacctg gacgccgaga aggtgggccc
    19981 gctcgtcctg gacgcggcgg cccggctcac gaccgccttg accgaacctc cacgctgacg
    20041 gtcgccccgc accggccgcg gcccggcgaa ggccgtgttc cggtcgcgcc tggccgcacg
    20101 cttgacatcg gggcgggcat ggcgaatcgt cgtacatata taggacatgc tcgtccgata
    20161 gccggacaca tggaggcgtc atgccgtact accgggtggt cggggaggtc ccgcgcaagc
    20221 gccatgtgca gttccgcgcg cccggcggcg gactgtacaa ggaggagctc atgggagagg
    20281 agggcttctc ctccgactcc tcgctgctct accaccgcca cgcgccgacg gcgatcgtca
    20341 aggccgaggc cgtggacgcg ggaacgcccg ctctcacgcc gaacctgccg ctctcccccc
    20401 ggcacttccg cacccaggac ctgaagcccg gcggcgacct ggtctccggg cgcctgccgc
    20461 tcgcgggcaa ctccgacgtc cgcatctcgt acgccgcgtg cgacgccccg agtgagctgt
    20521 atcgcgactc gatgggcgac gagtgcgtgt acgtcgcgag cggccgggcc aggttcgagt
    20581 cggcgtacgg cgcgctggac gtgaccgagg gcgactacgt ggtcgtcccg accgggaccg
    20641 tccaccgctg ggtgcccgag ggaccggtga ccgcgctggt gatcgaggcg gccgggcaca
    20701 tcaggccgcc gaaacgctac ctgtcccagt acggccagtt cctggagcac gcgccgtact
    20761 gcgagcggga cctgcgggcg ccggccgagc cgctgctcgt ggacggcgag gaggtgccgg
    20821 tcctggtcag gacgcggggc gggctgacca ggctgaccta cgccaaccac cccttcgacg
    20881 tggtcggctg ggacggctgc ctctatccgt acgcgttcaa catccgcgac ttcgaaccga
    20941 tcgtgaagcg gacccacgcg ccgccgccgg tccaccagac gttcgagggg cccggcttcg
    21001 tcgtctgctc gttctgcccc cggccactgg acttccaccc ggaggcggtg ccgatcccgt
    21061 acaaccacca caacgtggac tccgacgagt tcatgttcta cgtgggcggc gactacacgg
    21121 ccaggaaggg atcgggcatc gacgtcggct cgatctcgct gcatcccgcg ggcttcacgc
    21181 acggccccca gccgggcgcg gtggaggccg ccgtcgaggc cgtgcgccag ggacacaccg
    21241 agacgaccga gatggccgtg atgatcgaca cgttccgccc gctcgacctc gggcaggccg
    21301 ccctcgcgtg cgaggacacc ggctacgcgt ggacgtgggc ggcgcggcga tgagcttcgg
    21361 cctcggcaac ctgccgtacg gcgtgttctc ccgggccggg gagccgcgca gggtcggcgt
    21421 ccgggtcggg gaccacgtcc tcgacctggc ggccgccctg ggcagggacg tcttcgccgc
    21481 gcccagcctc aacccgttcc tcgccctcgg ccgcacggcc tggcaggagg cgcggggacg
    21541 ggcgcgcgag gccgcggccg cgggcgacca cctgatcccg ctgacggagg tcaccctgca
    21601 cctgccggtc gaggtggccg actacgtgga tttctacgcc tcactggagc acgcgtccaa
    21661 tctcgggcgc atcctgcggc cgggcgagga gccgctgaag ccgaactggc ggcacctgcc
    21721 cgtcggctac cacggccggg cgggcagcgt cgtggtgtcc gggacgccga tcaggcggcc
    21781 gtgcgggcag cggccgtcct tcgggccctc ggccaggctg gacatcgagg cggaactcgg
    21841 cttcgtcgtc ggcgtgccgg cgccgctcgg cgggcgcgcc ggcgcgttcg aggaccacgt
    21901 cttcggggtc gcgctcgtca acgactggag cgcccgggac atccaggcgt gggagtacgt
    21961 cccgctcggt cccttcctgg gcaagtcgtt cgccacctcc atgtcggcgt ggatcacccc
    22021 gctggaggcg ctggaggagg ccagggtcga gggccggtcg caggacccgg agccccttcc
    22081 gtacctgacc aggcagacgc cctggggcct cgacctcacc ctgcggatcg acctgaacgg
    22141 cgagacggtc tccacgcctt cgtaccgcga catgtactgg actcccgacc agatgctcgc
    22201 ccacctgacc gtgaacggcg cgggtctccg caccggcgac ctgttcgcga gcgggaccgt
    22261 ctcgtcggcc gggcagccgg gctcgctcat cgagctgacc tggaacggcg ccgagccggt
    22321 gaagctgccg gacgagaccc gcacgttcct ggaggacggc gacaccgtga cgatcacggc
    22381 ctggacctcg cacgggatga gcctcggcga ggtgtcgggg acgatccttc cggcgactta
    22441 gcgtgtttct gtcgtcaccc ctcgctatct t
//
