LOCUS       NZ_VANP01000007        26426 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold7, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000007
VERSION     NZ_VANP01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 414745)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 414745)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 195761
            Orig. end                         :: 222187
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26426
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26426
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26426
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16426](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16426
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(1055..4129)
                     /locus_tag="FED44_RS19955"
                     /old_locus_tag="FED44_19960"
     CDS             complement(1055..4129)
                     /EC_number="3.1.21.3"
                     /GO_component="GO:0019812 - type I site-specific
                     deoxyribonuclease complex [Evidence IEA]"
                     /GO_function="GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623406.1"
                     /locus_tag="FED44_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19960"
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="WP_138461633.1"
                     /transl_table=11
                     /translation="MAKGIREREFQNLMIQWSLPMGWAFTAGRSLPRETTQTIVAGQLR
                     DAIVRLNPDVIEGFDVDALVEEIIATVNAVEGGLVRANEQVLRLLRGRKEFRDADGVWH
                     ALKVIDLEHPNANTLVVSDEVTITVPGKTSRRFDLVYWVNGLPLVVVEVKSPTTKSSWA
                     DAAREINDVYVTEYPWFFTPNVFAVASDGLKLRFGAAGAPTYLWQPFRSTADDENLSGQ
                     ADVQRSVELLLNPATVLDMLANFALFDTSGGGVDKKYLPRYPQMEAAHLIHERVLAGGQ
                     KGLIWHHQGSGKTLLMVFAASLLLADTRTESPTIILLSDRTQLVRQTSGVFTSALGDAY
                     FHQPATSQELRSLLADDVRGVISTTVHKFADAGKNLSTRRNIIVLVDEAHRTQSDRSES
                     LAGQMRGALPHAKFFGMTGTPVSNLATDTFALFGEETDPDRVLHRYSVSRSLLDGATVP
                     IMLDPHPVAFEINDQALQAEFDQFADNFDLDDPDRESLSRKFGRLTSVFTNPDRIHAVC
                     QDIVDHYLAGAYRNGLKAQVVAYNRELAVAYTDKINELLAGFGASQVLAEVGKHDRITA
                     EVNISISDSKDEDRAMRPFQLSEAEEEEQKRRFLTPDDPLCFLVVTAKLMTGFDAPNEG
                     VLYLDKPLKAHTLFQTITRPNRTWVSPTGFVKTSGVVVDYIGLAEEVQRAVVDPTSPRA
                     GKGGGFVTDLSELVAEFRATFARIEDLLVDVDGLDLTVHGYESVRAINVFLDANPGAAE
                     VFSKDYRLLARLYPLINTDKRVDKYRDGFGLFGSVYTTLFKRSSDEERKDRLSELGPMV
                     LKIINAHVHSFSVVASQEEALVLDAQGIAILKELLALVRPKPGKDDGEDKTPPSAAEIL
                     DHIKASLDKGVEPGSAKYTALAERIKLLRDRIIQNAQDALEFLSEALRIARAIVDAEKH
                     PNEAVVLDDDHVGVLSRIIHDHAPSGFSVMERNLAEEIDQVVTRTLAGSWDNADARNRG
                     VRRATAAVFRRYTLKPVGEPYDSTVAYIEAHYLVD"
     misc_feature    complement(3080..3082)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3434..3436)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4133..5302)
                     /locus_tag="FED44_RS19960"
                     /old_locus_tag="FED44_19965"
     CDS             complement(4133..5302)
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /locus_tag="FED44_RS19960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19965"
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_208759077.1"
                     /transl_table=11
                     /translation="MTDGYPLRPLGEVIRLDIQRTPMMPATTYRLAGVLNAGQGLVAKG
                     ELDGGDTEYASMNVLRVDQVVMRKLTAWEGPITVVPAEFDGFVVSSEFPTFTLGPELVP
                     DWMRHVCRSPRLWAEMKNRVSGTVQRRKRLNPEHLLQIKLPIPPREVQAGIVEILDAVD
                     DQITALEAEVEAVVKVRTGLVGRSADTGQVPLGSLGVVSQGKGLPKEFQGKRTGEVSWY
                     KIADMTGPGNEFGYTVADTRLTPSEVAEIGGVVVEAGAVTFPRVGAAVLTEKKRIVDTP
                     GALDENHLVITPGKGTNSEYLLAVMESFALSSLVRPGAVPSLNMGLIRSTKVPWSWREN
                     QSLGTALGALRAESRVLAAEAARLREVRAALLAGMLDRSIDIESAELEG"
     gene            complement(5295..6866)
                     /locus_tag="FED44_RS19965"
                     /old_locus_tag="FED44_19970"
     CDS             complement(5295..6866)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008170 - N-methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006306 - DNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017618478.1"
                     /locus_tag="FED44_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19970"
                     /product="type I restriction-modification system subunit M"
                     /protein_id="WP_111699030.1"
                     /transl_table=11
                     /translation="MAVTQQEIENRLWDAADELRVAMPEAQYSSVIFPLMFWKYLSDTW
                     EHQHEEFLADNEGLDGLSAEEAHEIEYRDYQSFEIPFLYPGTVQQRRASWSSILATITQ
                     PGLGKRVRASLQAIETANPDKFSRLFGSMTWTAEEVLPGEVLAAVMQAMDRTPKMHEGN
                     MSHDVLGGAYEYLLKRFSDGSGTRAGQFFTPREVVELIVEVLEPKGFESVYDPTCGSGG
                     MLIASANLLKARGGRGYTLSLYGQEAVPDMAGVARMNLFMHNLTQFQVEVGDTLKDPRF
                     KKPDGSIAQFDVIVANPPYSQKWKPWTNDPRAIGGVAPRSSADWAFVQHMIASMGPKKG
                     RAGVVLPHGVLFRGGQEAAIRKRVLEDDLLEAVIGLPANLFYSTTIPTCILVFRAPGTK
                     AAERKDGVLFIDASKRFAKAKNRNIFTDADIADVVTAYRSSFDASNPVGPDGEGGLSAR
                     FVPTTEIVANGYDLNIGRYIKQAAVEQEDLDTLIAAYNIARAERQRTEQRMLAVLAAAG
                     IEGFDD"
     misc_feature    7200..7213
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    complement(7423..7437)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            7440..8480
                     /locus_tag="FED44_RS19970"
                     /old_locus_tag="FED44_19975"
     CDS             7440..8480
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_19975"
                     /product="hypothetical protein"
                     /protein_id="WP_244302094.1"
                     /transl_table=11
                     /translation="MVILSARESARLGEQMDTTPFGSFTVEEITNELRQLATLYPSRSP
                     LESLLAARALRDRSFALAQQSRRPSYARDLYLVTAWSCAILANASFDLGAVAPAFTQTR
                     AALHLGDLCDHNGVQVWVRGLQALVAFWDDRPDEAIAYAESALERPAEAGTATVRIEAI
                     YARALALQGRDQESGRALARVERARDRVTETGNPLDGPGGMADFPRAKELYWRANTYLL
                     TGNPQRLPDAEASAMESVHLYTETNAVSPRPGELCHARLDLASARWGSGHPEGAEQQVG
                     AVVETLQTRYVESVVRRMNGFGKLVESECGGRSALAGQVLARIADIGAIAPPSLPSDIA
                     ALPLDE"
     misc_feature    7587..7589
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8366..9334
                     /locus_tag="FED44_RS19975"
                     /old_locus_tag="FED44_19980"
     CDS             8366..9334
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="FED44_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19980"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_138461635.1"
                     /transl_table=11
                     /translation="MRWAQRPGGASARAYRGHRRYRPAVAAQRHRGAAARRVTAPRTIA
                     VLHPGAMGAGMARVLKGAGHRVLCGLEGRSEETRRRAERAGLISISMPQLAAEADIALS
                     VVAPSAAQEVADQLLAAGFRGLLIEANAIRPALCHAIAERVRAAGGQVVDASIMGPPPT
                     QSVTQPTRLYLSGPPPCVDIATELFMSTAALHVTKLGAELGKASALKLAQSVVQKASRA
                     LALLGHALADRHGLSAQLAAEARRWPHPASDPERFSSVAGRSWRWGDELRDAAQELREA
                     GLPPELATDAAALFDLLAGFEGGQPAVDDIFRALTDGSAEP"
     misc_feature    9245..9247
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9742..9933
                     /locus_tag="FED44_RS19980"
                     /old_locus_tag="FED44_19985"
     CDS             9742..9933
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573280.1"
                     /locus_tag="FED44_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19985"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_111699036.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.8e-15, bitscore:
                     51.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSNLGPVQGHPSGSPALGAAARRGPFDLDVSVVEAADAGSLISV
                     TDDGCGTTCPKACTTGSR"
     CDS_motif       9742..9867
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSSNLGPVQGHPSGSPALGAAARRGPFDLDVSVVEAADAGSL"
                     /locus_tag="FED44_RS19980_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9868..9933
                     /prepeptide="core"
                     /locus_tag="FED44_RS19980_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-0.40"
                     /molecular_weight="1947.1"
                     /monoisotopic_mass="1945.9"
                     /core_sequence="ISVTDDGCGTTCPKACTTGSR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSSNLGPVQGHPSGSPALGAAARRGPFDLDVSVVEAADAGS
                     L"
                     /leader_location="[9741:9867](+)"
                     /alternative_weights="1965.2"
                     /alternative_weights="1983.2"
                     /alternative_weights="2001.2"
                     /alternative_weights="2019.2"
     gene            10001..13105
                     /locus_tag="FED44_RS19985"
                     /old_locus_tag="FED44_19990"
     CDS             10001..13105
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="FED44_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19990"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_208759078.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.4e-196,
                     bitscore: 647.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.9e-18,
                     bitscore: 60.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.9e-24, bitscore:
                     79.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDTPCFRASGVALVRAAAHTDLGLPPWPDLTGRAPERLREWCDW
                     LDQVWSLPVVADALDHAAPSLAEQVRALLAASNPSPDKARRCVLSVARYLLRMTGRATP
                     LGLIAGVAPAAMAAAGETAGLRWGSRHQAIARAGADWLAAVIHQLEICHELLLRLPVVT
                     NSAVLVRGDRLIVPYQPNPDRGGGAVEVSLRYTTAVAVALDAARAPIRLEDLVAKIAPD
                     FPTTNPATVTGMLNELVARRALVTSLHAPSTVPDALDYLLQELDTADAQTIPAAAALVG
                     GLREIHDLLHAHNQAPLAQSLMLREEAAAQMRAIAPSRRHPVAVDLRLDADLVLPREVV
                     AEVERAALVLSRLSAYPYGTPAWRAYHERFFDHFGIGSSVPLADVVADSGIGWPEGYPG
                     TGTEEPRSPMSHRDQMLLALAQRAALDGAGEITVTDAMIAALELGPQVPRVPPHLELGV
                     RVYATSVEAFREGRVRVEVVTVSRSAGTLIGRFLPVLDSGDSARLTAALADMPSGGPGT
                     VCVQVSFPPLDPATAHVARSAQVLPTVISLAEHRAPGWNVLTPDDLAVACDGRRLVLTA
                     PAPGIRVHATAMHALALGTPTPPLARLLSELSRAPYAQVTTFSWGAAAHLPYLPRIRYG
                     RIILSPARWRLDAADLPAPREEWSTWDDAWAGLRQRLRVPRLVHLVHGDQRLPLDLDHS
                     GHRVLLRTHLNRDRDAILAEAPTPEDTAWCGGRAHEVIIPLAATGTPEWPRMPTPSRAR
                     TLPRGHGDAPAASTVLMASLYGAVQRQDVILAEYLPTLLRRLGNPSWWFVRYRDPGPHL
                     RLRITLPAREAFGAVAGTVSDWADDLHRIGLLRELRYCTSYPEIGRWGDGPAMTAAEHV
                     FTADSRAVLAQLRQPARPDRQALAAAHAVAIAAAWTGSTEAGMRWLIEHVAPAAPGKVS
                     RPVFTEAVRIANPGDNWAGLRGAPGGDAIAAAWADRAIAVADYRTHLPGPHTQGVDPDN
                     VLVSLLHVNYIRVCRIDPADEAECMYLARSAALAWTVRITKGGHP"
     aSDomain        10481..10753
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FED44_RS19985_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="3.80E-19"
                     /identifier="RREFam001.1"
                     /label="FED44_RS19985"
                     /locus_tag="FED44_RS19985"
                     /protein_end="251"
                     /protein_start="160"
                     /score="60.2"
                     /tool="antismash"
                     /translation="VVTNSAVLVRGDRLIVPYQPNPDRGGGAVEVSLRYTTAVAVALDA
                     ARAPIRLEDLVAKIAPDFPTTNPATVTGMLNELVARRALVTSLHAP"
     misc_feature    11771..11773
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11885..11887
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12002..12004
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13102..14352
                     /locus_tag="FED44_RS19990"
                     /old_locus_tag="FED44_19995"
     CDS             13102..14352
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610917.1"
                     /locus_tag="FED44_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_19995"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_138461637.1"
                     /sec_met_domain="LANC_like (E-value: 6.8e-46, bitscore:
                     151.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTDPLEVAVHVADRLARPEDSGLRAGESWWPQSLAHGAPGVALL
                     HVELAAHGAAPWDRVHAWLCAATWATVTGGPDSHLYYGAPAVAHVVACAADHQPGAYRR
                     ALDALNRQITADALSRARAGHARIDADTLPTLSEFDVIRGLSGIGAYLLRRDPGGAALT
                     AVLEYLVRLTEPITVDGETLPGWWAQVGPSGRSDPALPGGHANHGMAHGVGGPLALLAL
                     AALHGVTVTGHHDAIARILTWLDQWRTHNGWPYWVTRPQLHAGQLMATPVRRPSWCYGT
                     VGLARAQQLAALATGDSTRRRHAENALLRAVTDPMHLLAATDDSLCHGRAGFAHLALRA
                     AADAAPDPGVQLRAAALRLLEVMHPPGTDAKDTAGQLLTLAGPEFLEGTAGIALTFAAT
                     ASPSGPVTGWDTCLLIS"
     gene            14369..16426
                     /gene="fxlM"
                     /locus_tag="FED44_RS19995"
                     /old_locus_tag="FED44_20000"
     CDS             14369..16426
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="FED44_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_20000"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_138461638.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-31, bitscore:
                     104.5, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 3.3e-43, bitscore: 142.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPWLQCNIHFSDPTSEFQVAAADLLPPLAAAQGDGHLHAWWYIRK
                     NGVWRLRYRGGPQVVANLLDTLAADGRITGWEPGIYEPETLAFGGPQSMDVAHELFHRD
                     SCHVLSRAAEPGPAARQRETSILLCAALMRAAGLDWYEAGDVWAQVAEHRPIDPAKPAW
                     PPEREIGLQAVMHRLLTADARSLPALPTGWLDAFEEAGQSLASLAHQGRLQRGLRAILA
                     HHVIFHANRAGLPVTDQSAIAALAVHTVFTPAADRIFPAQNLFPKAKVPPMTLIDDQPD
                     VTPEELRDALTDRLVAAGTVRTPSVEAAFRTVPRHLFVPSASLDAAYGDDPIYTKHDGA
                     GVSLSAASQPTIVGMMLEQLNAEPGQRILEAGAGTGYNAALIATIVGPQGHVTTIDVDD
                     DLVTGARDHLAAAGIGNVTVVLADGALGHPENAPFDRFIATVGAWEVPAAWLDQLTPEG
                     RLVVPLRLRGVASRAIVFERDENGWHSVDHQLATFMPLRGIGDDARRTVAITAERDVTL
                     QVHKDQAADPTELAGVLDTNRVETWTEVTIPATVSYELLDLWLCLRLDNPLMRMHVGSE
                     ATTRGTVTPMFPWGSMATTSGNSLAYLISRCTAERDSADVPLYEVGVVGHGPSGAELAE
                     HVANEIRTWNQDYRDRAVRFELPDTPPSADPGTGRFVLSRPTHPILVTWE"
     gene            16433..17548
                     /locus_tag="FED44_RS20000"
                     /old_locus_tag="FED44_20005"
     CDS             16433..17548
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20005"
                     /product="hypothetical protein"
                     /protein_id="WP_138461639.1"
                     /transl_table=11
                     /translation="MEPTQAFARFPLVARPRPACAPLDARVGNLCELARTAERDSDTST
                     ASTVFNQAALLASDLGLPDLARTWCHQHATLYLTACPLTGRAARHAVEPLVNLARLHIR
                     AGDGAHAFALLDGLYEAAQARTDTTVDELHVPFSILTQTVADHRDVLQWLWTVHLADGT
                     RALTGAGRWNEALAHLRARNGVGHRMLDGRQVAVIAHALAGDTATTQALLDGTPAGEPW
                     EAAVTACLAALCRPGDDRTAAEMLTCYRRLDHTAPGLVVFRTRLGLSVVDAAGGVDTAD
                     GRAVATTLIIRAVATDDGYAARDVLDHPGCAAILKADQKAALTQLLQASGLGSRRFPEW
                     LMVELSVALSRSGAVIARNLNSCLVDAERMG"
     misc_feature    17408..17410
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17645..17659)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    17652..17667
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.77"
                     /tool="antismash"
     misc_feature    17656..17676
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.78"
                     /tool="antismash"
     misc_feature    complement(17778..17793)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.88"
                     /tool="antismash"
     misc_feature    17781..17796
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.75"
                     /tool="antismash"
     misc_feature    18779..18792
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.67"
                     /tool="antismash"
     gene            18976..19650
                     /locus_tag="FED44_RS35890"
     CDS             18976..19650
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="FED44_RS35890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bacterial transcriptional activator
                     domain-containing protein"
                     /protein_id="WP_167521539.1"
                     /transl_table=11
                     /translation="MRFTRAEGRNLFALLATTKDGVRQDLVIEHLWPEQGEHGSQHLET
                     GVRDINAALRSATGLSTGVKFVIKTGQCRHLASAFFDIDLWRFEQARLVANTALEEDTR
                     VQALRQMVAIHEGPLLAERDDLWCLPLRQAAARKATNAVMRLAELEHKTDPDHALDLLT
                     LAVDRIDPYSEVLWCRIMTIHGELGRLPAVRATFQQLTERLREVDAEPSRQARQIYRGL
                     AG"
     gene            complement(19744..20127)
                     /locus_tag="FED44_RS20010"
                     /old_locus_tag="FED44_20015"
     CDS             complement(19744..20127)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20015"
                     /product="hypothetical protein"
                     /protein_id="WP_138461641.1"
                     /transl_table=11
                     /translation="MSGKGYQTLLECRRRGFHLRGHGFTVDQIAVVLSFDHDVAPLRLY
                     RDAVGLTAAQVVATFNALERTGTAPLRESRLYEYESWPESGRRPPAHVLRLLAQIYGTR
                     PAQLLTPETRATYSRQDRVLLGA"
     misc_feature    20256..20269
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            20389..20922
                     /locus_tag="FED44_RS20015"
                     /old_locus_tag="FED44_20020"
     CDS             20389..20922
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20020"
                     /product="ATP-binding protein"
                     /protein_id="WP_133305908.1"
                     /transl_table=11
                     /translation="MTGRENADATVLDDGGRDGFPGLPLGPALVRRWWSGLGGPMLWRR
                     RFHGREDQVTAARKMVRLLLEDTSRADDAEWITAELAANALLHSRSGLLGGLFMVEVLR
                     GLHMARITVYDLGGEGTPAVQARKPGQDIGEHGHGLRGVRQLATQAGVRGDATTGHAVW
                     AQLALNCGASARTA"
     misc_feature    21050..21064
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.2"
                     /tool="antismash"
     misc_feature    complement(21219..21234)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.26"
                     /tool="antismash"
     misc_feature    21690..21704
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.14"
                     /tool="antismash"
     gene            22649..23776
                     /locus_tag="FED44_RS20020"
                     /old_locus_tag="FED44_20025"
     CDS             22649..23776
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20025"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_138461642.1"
                     /transl_table=11
                     /translation="MVAITVTENAYGMDANAISAARDTDDSAPDIHTGTALNTREEAVW
                     AALAASPGTSVALIAGAAGISRVTAGKILNQFEAEGRASRVPGGHDGRGRTPDLWYPAE
                     DTTVSEGNAPDEASDSPAEVPGPDDPDDPNVPAVMDMSEDDGDGADEEEATAAAVPATD
                     GQFDQADPEGVVSADVAGDDPVPDSGDVGHALDEALDSRADATDTDTDVPADGSEETAE
                     AEDPAWAWARTALLELADLITGAVGAFDDDGDAVTALGRLEMAMAKAPQAHRDARAVLT
                     GTNPSGRGTGGRVSTGGTTGAGGARPGHLRDRVLSHLLDHPGKDFTPYEIGRVLESSSG
                     AVANALDRLVGLGQAELTCERPRRYALAVNPAPGD"
     misc_feature    complement(22650..22665)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.72"
                     /tool="antismash"
     misc_feature    22670..22681
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.88"
                     /tool="antismash"
     misc_feature    22687..22698
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.75"
                     /tool="antismash"
     gene            24021..25022
                     /locus_tag="FED44_RS20025"
                     /old_locus_tag="FED44_20030"
     CDS             24021..25022
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03299.1"
                     /locus_tag="FED44_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_20030"
                     /product="DUF932 domain-containing protein"
                     /protein_id="WP_138461643.1"
                     /transl_table=11
                     /translation="MAHEIEIFADGSAGFAAGIKPGWHRLGYTAPGPMTAEELLARAQL
                     AAWNVRKVPVGTVTDPDTGRSVTAEEDFLVVRTNPVTGEPERLGMVGKDYKVVQNEEVA
                     EFLQTLVDESGAIFDTGGSLNGGRRVFVTMRLPEPLMVGGFDRVDLYLAAFSRHDGWGA
                     FTTVATPVRVVCANTERAALRNHASMFKVRHTGHIAGRIAEAREALKLTWRHGEAFAAE
                     AERLLATPMDLKEFRQFAAALHPMPTDAKPVTRRNYELAMRQLELLFTDAPTNEPIRGT
                     RWAAYNAVTERLDHCSPVIGRREAEIVRAERALLDDHAHSKIKTRAFQMLAA"
     gene            25187..25621
                     /locus_tag="FED44_RS20030"
                     /old_locus_tag="FED44_20035"
     CDS             25187..25621
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20035"
                     /product="hypothetical protein"
                     /protein_id="WP_138461644.1"
                     /transl_table=11
                     /translation="MGPFEQIAIDYLIDATRTLDEAASRFASAWETGECVTAEDLSRAA
                     VAQHLRDWWQQVMNQIDADEAVDTVTAIMESRRAAEAYLISASQLSYGELFTQAMAQAR
                     RQAARQFLDSTRHLAEALTGPTAAGRSVPATGSAGGEVRA"
     misc_feature    25628..25644
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            25663..26277
                     /locus_tag="FED44_RS20035"
                     /old_locus_tag="FED44_20040"
     CDS             25663..26277
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_20040"
                     /product="hypothetical protein"
                     /protein_id="WP_138461645.1"
                     /transl_table=11
                     /translation="MNVGTESATGDAAGEPAGGWQLGPLQELSGPPPPERSTLPGAPTT
                     ATAPSFADTFAGPEAPDGGEAERLAARVAEVVAHARHADYAASAALVCQIQRGHQLTSE
                     PLYSVVYSHALRTWWEQVPAQISENSVDVVHAVRRVRAWARHHLTGEPAAARPGTLFDH
                     ALAHTSRAAARHFLAASGELLASRADAETATAEPSQHQNGR"
ORIGIN
        1 ctgagtttac gcttgacgac ctccgctcgg gaataaacgc gatcgtcgac gatctaatcg
       61 ctgagaagat caacgcacta cctctggacg ccgcggtggg agacctcgtc gccgaaggac
      121 tcatccgtga gcagagcccc gggcggtaca cgcttctggt tcgcgacctg tttgcggaag
      181 atcgacccgg ctacagcccg atcgaagagg caacccgggc ggcacacacg ttataccgcg
      241 accgaccatt acctgacacg gcagctgtag atcttgatgt gtgaggtgtt cctgcaggtc
      301 acgccatgcg ggtgggttgt cgtgtcgtaa gctgagctgc cacagcgcgc tggtacttcg
      361 cggcatacaa atccgacgca gcgaagtcgt gctgcagcag cgtcagctgg ctgctggccg
      421 tcgccgggca cggtcgtcca cggacactca cgacgggagc gcgctcccgt gatgtccagc
      481 tcgcgcatca gccgttctcg actgatccgc tgttcgtgaa tatcgatgtc ctgggcctac
      541 accaccgttc gcggccttaa cggaacttaa atgggtcttg tcggtgagct gacgagggct
      601 gatctgatct gtatgaccag ggtgtgcggt atgtgcaagg cggcggcttc accccccagg
      661 agcaggggcg ttcgaggagg cacggctgcg agcggccgag atgttcgagc agggggtcac
      721 gaacgcggcg gtagcccgga cgttgcgggt cacgcagagg tcggtggact ggtggcggcg
      781 cgcctggcgc gagggcggca cggcggtgca tgaggctcat agcgcggact gtaacaatcg
      841 cccccgacaa aactgcctgc ccactctcgc ccggccccgg cgtcaagctc ttgctctcgc
      901 gcctctacct ccgcactaac ctgcagctga gacgagctga tcagaaagct gcgcggagta
      961 ctggatcgcc agcaggcgtg gcccaggggg tagatcaggg cgcgagcagc gcgacggggc
     1021 cgacagtcgc tacaggttgc cgggcctcgg ttcgtcagtc gactaggtag tgggcttcga
     1081 tgtaggcgac ggtggagtca tagggctctc ctaccggctt caacgtgtac cggcggaaga
     1141 ccgcggcggt ggcgcgacgg acgccccggt tgcgagcgtc ggcgttgtcc caggagccgg
     1201 cgagggtgcg ggtgaccacc tggtcgatct cctcggccag gttcctctcc atgactgaga
     1261 atccggacgg tgcgtggtcg tggatgatcc gcgacaggac acccacgtgg tcgtcgtcca
     1321 gcacgacggc ttcgttgggg tgtttttcgg cgtccacgat ggcgcgggcg atccgcagtg
     1381 cttcggacaa gaactccaag gcgtcctggg cgttttggat gatgcggtcc cgcagcagct
     1441 tgatccgttc tgcgagggcg gtgtacttcg cggaccccgg ttcaacgccc ttgtcgaggg
     1501 aggccttgat gtggtccagg atctccgccg cggacggcgg cgtcttgtcc tcgccgtcgt
     1561 ctttgccggg cttggggcgg acaagggcca gcagttcctt gaggatggcg atgccctggg
     1621 cgtccaggac aagggcttcc tcctgggagg cgaccacaga gaaggagtgg acgtgggcat
     1681 tgatgatctt caggaccatc ggccccagct cgcttagccg atccttcctc tcctcgtcgg
     1741 aggacctctt gaacagcgtc gtgtacacgg acccgaagag cccgaagccg tcccggtatt
     1801 tgtcgacccg cttgtcggtg ttgatgagcg ggtacaggcg ggccaggagc cggtagtcct
     1861 tgctgaacac ctcggcggcg ccagggttgg cgtccaggaa gacgttgata gctcgtacgg
     1921 actcgtaccc gtggaccgtg aggtccaggc cgtccacgtc cacgagaagg tcttcgatgc
     1981 gggcgaaggt ggcgcggaac tcggcgacca actccgacag gtcggtgacg aacccgccac
     2041 ccttgccggc cctcggtgag gtggggtcga cgacggcccg ctgaacctct tcggccaggc
     2101 cgatgtagtc cacgaccacg ccggaggtct tcacgaaccc ggtcggggac acccaggtac
     2161 ggttcgggcg ggtgatcgtc tggaacaggg tgtgagcctt cagcggcttg tccaggtaga
     2221 ggacgccctc gttgggggcg tcgaaccccg tcatcagctt cgcggtcacc accaggaagc
     2281 acaatgggtc gtccggggtg aggaaccgcc gcttctgctc ctcctcctcg gcctccgaga
     2341 gctggaacgg ccgcatggcg cggtcttcgt ccttggagtc cgaaatggag atgttcacct
     2401 cggcggtgat ccggtcatgc ttgccgactt cggcgagcac ctgtgacgcc ccgaagccgg
     2461 ccagtagctc gttgatcttg tctgtgtacg ccacggccag ctcacggttg taagcgacga
     2521 cctgggcctt gagaccgttg cggtaggcgc cggccaagta gtggtccacg atgtcctgac
     2581 aaaccgcgtg gatgcggtcg gggttggtga acacggaggt gagacgcccg aacttgcggg
     2641 acagggactc acggtcggga tcgtcaaggt cgaagttgtc ggcgaactgg tcgaactcag
     2701 cctgcaatgc ctggtcgttt atctcgaagg cgacagggtg cgggtccagc atgatcggga
     2761 cggtcgcccc gtccagcaga gaccgggaga ccgagtaccg gtgcagcacc ctgtctgggt
     2821 cggtctcctc gccgaagagg gcgaaggtgt cagtggcgag gttgctgacg ggggtgccgg
     2881 tcatgccgaa gaacttcgcg tgcggcaacg ctccacgcat ctgcccggcc agggactccg
     2941 acctgtcgga ctgggtgcgg tgtgcctcgt cgaccaacac gatgatgttg cgccgggtcg
     3001 acaggttctt gccggcgtcg gcgaacttgt gcacggtcgt ggagatgacg ccacgcacgt
     3061 cgtcggccag cagggaacgt aactcctggc tggtggcggg ctgatgaaag taggcgtctc
     3121 ccagcgcgga ggtgaacacc ccggaggtct gccggacgag ctgggtccgg tccgagagca
     3181 ggatgatcgt aggcgactcg gtacgggtgt cggccagcag cagcgaggcg gcgaacacca
     3241 tcagtagcgt cttcccgctc ccttggtggt gccagatcag acccttctga ccaccagcta
     3301 ggactcgctc gtggatcagg tgggcggcct ccatttgcgg gtagcgaggc aggtacttct
     3361 tgtccacccc acccccggag gtgtcgaaca gggcaaagtt ggcgagcatg tccagaacag
     3421 tcgccgggtt gagtaacagc tcgacggaac gctgcacgtc ggcctgaccg gacaggttct
     3481 catcgtcggc ggtggaccgg aacggctgcc acaggtatgt aggtgcgcca gcggcgccga
     3541 accgcagttt cagcccgtct gaggcgaccg cgaagacgtt gggggtgaag aaccacgggt
     3601 actcggtgac gtacacgtcg ttgatttcgc gggcggcgtc cgcccaactg gacttcgtgg
     3661 tcggggactt cacctcgacc accaccaggg gcaggccgtt gacccagtac acgaggtcga
     3721 accggcggga ggtcttgccg gggacggtga tggtcacctc gtccgacacg actagcgtgt
     3781 tggcgttcgg gtgctcgagg tcgatgacct ttagggcgtg ccacacgccg tcggcgtccc
     3841 ggaactcttt gcgcccgcgc agcaggcgca gcacctgctc gttggcccgg accagcccgc
     3901 cttcaacggc gttgactgtg gcgatgattt cctcgaccag cgcgtccacg tcgaacccct
     3961 cgatcacatc ggggttcagc cggacgatgg catcccgcag ttggccggcg acgatcgtct
     4021 gcgtcgtctc acgcggcagt gacctgcccg ctgtaaaggc ccatcccatg gggagggacc
     4081 actggatcat caggttctgg aactcacgct cccgaatgcc cttcgccacg actcagccct
     4141 ccaactcggc ggactcgatg tcgatgctgc gatccagcat ccccgccagc agcgccgccc
     4201 ggacttcacg gagacgggcg gcctcagccg ccagcacacg agattcggct cggagcgcgc
     4261 ctagcgcagt cccgagggac tggttttccc tccagctcca aggcaccttc gtcgaacgga
     4321 tcaggcccat attcaacgag gggacggcgc ccgggcggac caggctcgag agcgcgaagc
     4381 tttccatgac cgccagcagg tactccgagt tcgtcccttt cccgggcgtg atcacgaggt
     4441 ggttctcatc cagcgctccg ggggtgtcca cgatccgctt cttctcggtg agaactgccg
     4501 cccccaccct cggaaatgtc accgcgccag cctctaccac aacgccgcca atctcagcca
     4561 cttccgaggg cgtaagccgc gtatcagcaa cggtgtagcc gaactcgttc cccgggccgg
     4621 tcatgtcagc aatcttgtac caagaaactt cgcccgttcg cttgccctgg aactccttcg
     4681 gaagcccctt cccctgcgac acaaccccca ggcttccgag gggcacctga ccggtatcgg
     4741 cagaccttcc gaccaggccc gtacggactt tgacgacagc ctcgacctca gcctcgagtg
     4801 cggtgatctg atcgtcgacc gcgtcgagta tctcgacgat ccccgcttgt acctcgcggg
     4861 gtgggatcgg cagtttaatc tgcaagagat gctcggggtt gaggcgctta cgccgttgaa
     4921 ctgtcccgct cacccggttc ttcatttctg cccacagtcg cggtgagcgg cagacgtgcc
     4981 tcatccagtc gggcaccagt tctgggccaa gcgtgaatgt cgggaactcg ctgctgacga
     5041 cgaatccgtc gaactcggca ggtactacgg tgatcgggcc ttcccacgcg gtcagctttc
     5101 gcatcacgac ctggtcgacg cgcagcacgt tcattgacgc gtactctgtg tctccgccgt
     5161 cgagttcgcc tttagcgaca agcccctgtc ctgcgttcag gaccccggcc agacggtagg
     5221 tggttgcagg catcatcggt gtgcgctgga tgtcgaggcg tatcacctct ccgagcggac
     5281 gaagcggata gccgtcagtc atcgaagccc tcgatccctg cggcggcgag gacggcgagc
     5341 atgcgctgtt cggtcctctg gcgctcggcg cgggcgatgt tgtaggcggc gatgagggtg
     5401 tcgaggtctt cctgctcgac ggcggcctgt ttgatgtacc gtccgatgtt gaggtcgtac
     5461 ccattcgcca cgatctccgt ggtgggcacg aatcgcgccg agagcccacc ttctccgtca
     5521 gggcccaccg ggttgctggc gtcgaagctc gagcggtagg cggtcacgac gtcggcgatg
     5581 tcggcgtcgg tgaagatgtt gcgattcttg gccttagcga accgcttgga ggcgtcgata
     5641 aacagcaccc cgtccttgcg ttcggcggcc ttggtgccgg gggcgcgaaa cacaaggatg
     5701 caggtcggga tcgtggtcga ataaaagagg ttcgctggca agccgatcac agcttcgagc
     5761 aggtcatctt ccaggacgcg ctttcggatg gctgcctctt ggccgccgcg aaagaggacg
     5821 ccatggggta gaacgacgcc agcacggccc ttcttcgggc ccatgctggc gatcatgtgc
     5881 tgcacgaacg cccagtccgc cgacgacctc ggcgccaccc ctccgatggc gcgcgggtca
     5941 ttggtccagg gcttccactt ttggctgtag ggcgggttgg cgacgatcac atcgaactgc
     6001 gcgatggacc cgtccggctt cttgaagcgc gggtctttca gggtgtcacc gacctcgacc
     6061 tggaactgag tgaggttgtg catgaagagg ttcatacggg ccacaccagc catgtccggc
     6121 accgcctcct gcccatacag gctgagcgtg tagccacgcc cgccgcgggc cttcaggagg
     6181 ttcgcggagg cgatgagcat gccgcctgac ccgcatgtcg ggtcgtacac cgactcgaag
     6241 cctttgggtt ctaggacctc gacgatcagc tcgacgacct cgcgcggggt gaagaactgg
     6301 ccggctcggg taccggaccc gtcggagaac cgcttcagta ggtactcgta cgccccaccg
     6361 agcacgtcgt gggacatgtt gccctcgtgc atcttcgggg tgcggtccat cgcctgcatg
     6421 accgccgcca gcacctctcc cggcagcacc tcttcggcgg tccaggtcat ggacccgaac
     6481 aggcgggaga acttgtcggg gttggccgtc tcgatggctt gtagggaagc gcggacgcgc
     6541 ttgccgaggc ccggctgggt gatggtagcg aggatggatg accaggaggc tcgacgctgc
     6601 tggacggtac cggggtagag gaacgggatc tcgaacgact gatagtcgcg gtactcgatc
     6661 tcgtgcgctt cctcggcgga caggccgtcc aggccctcgt tgtcggccag gaactcctcg
     6721 tgctggtgct cccaggtgtc cgataggtac ttccagaaca tcagcgggaa gatgacggag
     6781 gagtattgcg cttcgggcat cgccacgcgc agctcgtcgg cggcatccca caaccggttc
     6841 tcgatctcct gctgcgtcac tgccatcagt cgggggtgtc cttgctcgtc aaagggcggc
     6901 ggccctaagg ccgtggtgtt cctactggtc gcccgatttc aggcacgccc ggcatgcaca
     6961 cgccggggtg gcctacaggg tgaatacacg cggagcgtgg tactccctgc gcggccgacc
     7021 tcccaacgat atccttcgcc gggatcacgg aattcggcca acggcccctc cctttggacg
     7081 tgctgatgcg tagaggcgaa cttccgtacc cgagggaccg tcagtcgcct ggtcgggcga
     7141 gcggttcgga ggtagaacca atcgggcgcc tggtcgctcg tctacgcgag gaacggggct
     7201 ggagccaggt caaactcgcg agtctgttat gcgacaggtc gggcaactct gctgccacgc
     7261 aagatcagat atcgcgctgg gagcggcgac accggatccc gggcccctac tggcggagct
     7321 acctcgccga cctatttgag gttcccgtgc agatgatgac agccgccgcg gcagcctcca
     7381 ggcaagaacg ccatatggcc aagtcgcctg tgcgtgtttt gtccccagat gtgggggata
     7441 tggtgatcct gtcagcgagg gaatcggccc gactgggtga gcaaatggat accacccctt
     7501 ttggatcatt taccgtagaa gagatcacca acgagctacg acagctcgcc actctctacc
     7561 cttcacgttc accccttgag tcgcttttag cggcacgcgc gctacgagac cgatccttcg
     7621 ctttggccca gcagtcccgt cgcccttcct atgccaggga tctctacctg gttacggcct
     7681 ggtcgtgtgc cattctggcg aatgccagct ttgacttggg ggccgtcgct cctgccttca
     7741 ctcagacccg tgccgcgcta catcttggtg acctgtgcga tcacaacggg gtgcaggtct
     7801 gggttcgagg tctgcaggcg ctggttgcgt tctgggacga tcgtcctgac gaggcgatcg
     7861 catatgcaga gtcggcgctc gagcggccag cggaagcagg caccgcaacg gtacggatcg
     7921 aggcgattta cgcccgagca ctggccttgc agggacgcga ccaagagtct ggccgcgcgt
     7981 tggctcgtgt tgagcgagcc cgcgaccgag tcaccgagac cggcaaccca ctcgatggcc
     8041 ctggcgggat ggctgatttc ccgcgtgcta aagagctcta ctggcgggcc aacacctacc
     8101 tcctgaccgg caacccgcaa cggctacctg acgccgaagc gtccgcaatg gagtcagttc
     8161 atctctacac cgagacgaac gccgtatcgc cacgtccagg cgagttgtgc catgcacgtc
     8221 ttgatctagc ctccgctcgg tgggggagcg gccaccccga gggagccgag cagcaggtcg
     8281 gcgcggtagt ggaaacgctt cagacgcggt atgtcgagag cgttgtgcgt cgcatgaacg
     8341 gtttcgggaa gctggttgaa tcggaatgcg gtgggcgcag cgccctggcg gggcaagtgc
     8401 tcgcgcgtat cgcggacatc ggcgctatcg ccccgccgtc gctgcccagc gacatcgcgg
     8461 cgctgccgct cgacgagtga ccgctccccg tacgatcgcc gtcctccacc caggggcgat
     8521 gggggccggg atggcccgcg tgctcaaagg tgctggccat cgcgtgctgt gtggcctgga
     8581 agggcgatcg gaggaaaccc ggcggcgagc ggagagagcg ggactcatat cgatctcgat
     8641 gccacagcta gccgcagaag cggacatcgc attgtcggtg gttgcaccga gcgccgccca
     8701 ggaggtggcc gaccagctgc tggcggctgg attccgcggg ctgctgatcg aagccaacgc
     8761 gatccggccc gcgctttgcc atgcaatcgc cgagcgcgta cgtgcggcag gtgggcaagt
     8821 cgtcgacgcc agcatcatgg gaccaccccc gacacagtcg gtcactcaac cgacccggct
     8881 gtacctctcc ggtccgccgc catgcgttga tatcgccacc gagctcttca tgagtactgc
     8941 tgcgctgcac gtcaccaagc tgggcgccga gttggggaag gcgtcggcgc tgaaactggc
     9001 ccagagtgtc gttcagaagg ccagtcgggc gttggcactc cttgggcacg cgctggccga
     9061 ccgacatgga ctgtcagccc agttggctgc agaggcgcga cgttggcccc accccgcctc
     9121 cgatcctgaa cgcttctcca gcgtggccgg ccgaagttgg cgctggggtg atgagctgcg
     9181 ggatgccgcg caggaactcc gagaggctgg ccttcctcca gagctggcga ctgatgctgc
     9241 cgcattattc gatctccttg ccggctttga aggaggccag cccgccgtgg atgacatctt
     9301 tcgggccctt accgacggct cggccgagcc gtaacccaag caggcggcat catgacgctc
     9361 gccgagaccg gatagtggcc cccagccagt tcccatcggc cctgtcctgg ccattccgcg
     9421 ttgctggtcg ctgggaattt catggcatcg aactcgtcgt gcgggaactt cgtcgccagg
     9481 aagggtgagg cggagggctg ctggacgacg gcaacgtgag cacgcgggac agccacgaca
     9541 gcgacggccc gtccctgatg ttcgcaccag cggagtccac gacggcgagt tcattcgcgg
     9601 ggcgctggcc gccccgcgat ggctccgtcc gcggcgtaac cgacgggacg gcggtggctg
     9661 gctcctattt cgggagcctg gccacgagca cgaccccgga ccggcgcggc ccggggagtg
     9721 aatccttcga ggaggatacg gatgtccagc aacctcggcc cggttcaggg ccacccctcc
     9781 ggctcccccg ccctgggggc ggccgcacgg cgcggcccgt tcgacctcga cgtcagcgtg
     9841 gtcgaggccg ccgacgccgg cagcctgatc tctgtcaccg acgatggctg cggcaccacc
     9901 tgccccaagg cgtgcacgac cggttcccgc tgacccgcac gagtcgatcc ggccggcgtc
     9961 tctcccgcgg ggcgccggct cccttctttc ggaggtgcgt gtgcccgata ccccctgctt
    10021 ccgggccagc ggtgtcgcgc tcgtccgggc tgccgctcac actgacctcg gcctgccccc
    10081 gtggccggac ctgaccggcc gcgctcccga gcggctgcgc gagtggtgcg actggttgga
    10141 tcaggtgtgg tcgctgccgg tggtcgccga cgcgctcgac catgccgccc cttcgctcgc
    10201 cgagcaggtt cgtgctctgc tcgcggcgtc gaacccatca ccggataagg cacgcaggtg
    10261 cgtgctgtcg gtggcccgct acctgctgag gatgaccggc cgggccacgc cgctcggtct
    10321 gatcgccggg gtcgccccgg ccgcgatggc agcagccggg gaaacagcgg ggctgagatg
    10381 gggcagcagg caccaggcga tcgcccgcgc cggggctgac tggctggccg ccgtcattca
    10441 tcagctggag atatgccatg agttgctgct acggctgccg gtggtcacga acagcgcggt
    10501 gctggtgcgt ggggaccggc tcatcgtgcc ttaccagccg aaccccgatc ggggcggcgg
    10561 ggcggtggaa gtgtcgctgc ggtacaccac ggcggtcgcc gtcgccttgg acgccgcccg
    10621 ggcgccgatc cgacttgaag acctcgtagc gaagatcgct ccagactttc cgaccacgaa
    10681 cccggcgacc gtgaccggga tgctgaatga gctcgtcgcc cgacgggcgt tggtgacgag
    10741 cctgcacgcc ccgtcgaccg tgccggatgc gctggactac ctcctgcagg agctggacac
    10801 agccgacgca cagaccattc ctgcggcagc cgccctggtg ggcggtctac gtgagattca
    10861 tgatctgctg cacgcccaca accaggcacc gctggcgcag tccctcatgc tgcgagaaga
    10921 agcagccgcc cagatgcggg ccatcgcccc ctcccgccgg cacccggtgg cggtggactt
    10981 gcgacttgac gctgacctgg tccttccccg ggaggtggtc gccgaagtgg agcgagccgc
    11041 gctggtccta agcaggttga gcgcctaccc gtacggcaca cccgcctggc gggcctacca
    11101 cgagcggttc ttcgaccact tcggcatcgg ctcctccgtg cccttggccg atgtagtggc
    11161 cgacagcggc atcggctggc ccgagggcta tcccggtacc ggcacggagg agccgcgctc
    11221 cccgatgtct caccgcgacc agatgcttct ggccttggct cagcgggccg cactcgacgg
    11281 cgccggcgag atcacagtga ccgacgccat gatcgctgcc ctggaacttg gcccccaagt
    11341 accacgggtt ccgccacatc tggagctggg cgtccgcgtg tacgcaacga gcgtggaggc
    11401 gttccgcgag ggccgggtcc gtgtagaggt ggtcacggtg tcccgcagcg cagggaccct
    11461 gatcgggcgg ttcttgccgg tgctcgactc tggtgactcg gcgaggctga cggccgcgct
    11521 ggccgatatg ccctcaggcg gcccaggcac cgtgtgcgtc caggtgtcgt tcccgccgct
    11581 ggaccccgcc acggcgcatg tcgcccgctc tgcacaggtc cttcccaccg tcatcagcct
    11641 cgccgaacac cgcgcgcccg gctggaatgt ccttaccccc gacgacctgg ctgtggcctg
    11701 cgacggccgc cgcctggtgc tgaccgcccc tgctcccggg atccgcgtcc acgccacggc
    11761 catgcacgcg ttagcgctgg gaacgcccac tccgccactc gcccgcctgc tgtccgaact
    11821 gtcccgcgcc ccgtacgcgc aagtcacgac gttttcgtgg ggagctgctg ctcatctgcc
    11881 gtacttacct cggatccggt acggccgcat catcttgtcc ccggcccggt ggcgtctgga
    11941 cgcggccgac ctgcctgccc cacgggagga gtggtcgacg tgggatgacg cgtgggccgg
    12001 gttacggcag cgcctccggg tgccgcgcct ggtccacctg gtgcacggcg accagcggct
    12061 ccccctggac ctcgatcact ccgggcaccg ggtgctgctc cgcacccacc tgaaccgcga
    12121 ccgagacgcc atcctcgcgg aggctcccac cccagaagac accgcctggt gcggcggacg
    12181 cgcacacgag gtcatcattc ccctagccgc caccggcacc ccggaatggc cgcgcatgcc
    12241 tacgccgtcc cgcgcccgca ccctgccacg cggtcacggc gacgccccgg ccgcgtcgac
    12301 ggtgctgatg gccagcctgt acggcgccgt gcaacggcag gacgtgatcc tggccgagta
    12361 cctgcccacc ctgctacgcc gactcgggaa cccatcatgg tggttcgtcc gctaccgcga
    12421 ccccggcccg cacctgcggc tccgcatcac gctcccggcg cgggaggcgt tcggggcagt
    12481 ggccggcacg gtcagcgact gggcggacga cctgcaccgc atcggcctgc tgcgggagtt
    12541 gcggtactgc acctcctacc cggagatcgg ccggtggggt gacggccccg ctatgaccgc
    12601 cgccgaacac gttttcacgg ccgactcccg cgccgtgctg gcgcagcttc gccagcccgc
    12661 ccgccccgac cggcaggcgc ttgcagccgc ccatgcggta gcgatcgccg ccgcgtggac
    12721 gggctccacg gaggcgggca tgcggtggct gatcgagcac gtcgctccgg ccgcgcccgg
    12781 gaaggtgtcc cgcccggtat tcaccgaggc ggtacggatc gcgaaccccg gcgacaactg
    12841 ggcgggcctg cgcggcgcac ccggcgggga cgcgatcgcc gccgcgtggg ccgaccgcgc
    12901 catcgcagtg gccgactacc gcacccacct gcccggcccc catacgcagg gagtggaccc
    12961 cgacaacgtg ctggtcagcc tcctacacgt caactacatc cgtgtctgcc gcatcgaccc
    13021 ggccgacgag gccgagtgca tgtacctggc tcgctccgcg gccctggcct ggaccgttcg
    13081 catcacaaag ggcggccacc catgacaacg gacccgctgg aggtagccgt gcacgtggcc
    13141 gaccgcctcg cccgccccga ggactctggc ctgcgggccg gcgagtcgtg gtggccgcag
    13201 tcgctcgccc acggcgcacc cggtgtcgcc ctgctgcatg tcgagctcgc cgctcacggc
    13261 gccgcaccct gggaccgcgt ccacgcctgg ctgtgcgcgg caacctgggc gaccgtcacc
    13321 ggcggccccg acagccacct gtactacggc gcacccgccg tcgcacacgt ggtggcgtgc
    13381 gccgccgacc accagcccgg cgcgtaccgg cgggcgctgg acgccctgaa ccggcagatc
    13441 accgccgacg cgctgtcccg cgcccgcgcg ggacacgccc gcatcgacgc cgacaccctg
    13501 ccgaccttgt cggagttcga cgtgatccgc ggcctgtccg ggatcggcgc ctacctgctg
    13561 cgccgcgacc ccggcggcgc ggccctgacc gccgtcctgg agtacttggt gcgtctcacc
    13621 gagcccatca ccgtggacgg ggaaacgctg cctggctggt gggcgcaggt cggtccgtcc
    13681 ggccgctccg accccgccct cccgggcggc cacgccaacc acggaatggc gcatggtgtg
    13741 ggaggccccc tggccctgct tgcgctcgcc gctcttcacg gtgtcaccgt gaccggccac
    13801 cacgacgcca tcgcccgcat cctcacctgg ctggaccaat ggcgcaccca caacggctgg
    13861 ccgtactggg tcactcgccc ccagctgcac gccgggcagc tcatggcaac gccggtccgc
    13921 cgcccgtcct ggtgctatgg aaccgtcggc ctggcccgcg ctcaacagct cgccgcgctc
    13981 gccacagggg acagcacccg ccgccgccac gccgaaaacg ccctcctgcg cgccgtcacc
    14041 gaccccatgc acctgctggc ggccaccgac gactcgctgt gccacggccg ggccggattc
    14101 gctcaccttg ctcttcgcgc ggcggccgac gccgcacccg acccgggcgt acagctccgc
    14161 gcggccgcac tacgcctgct ggaggtcatg cacccgcccg gcaccgacgc gaaggacacc
    14221 gccggccagc tcctcactct ggcgggcccc gagtttctcg aaggcaccgc cgggatcgct
    14281 ctgacattcg ccgccacggc gtccccgtcc gggcccgtca ccgggtggga cacctgcctg
    14341 ctcatcagct gaaaggacgg agacccgcat gccatggctt cagtgcaaca tccacttctc
    14401 cgaccccact tcggagttcc aggtggcggc cgccgacctg cttcctcccc tcgccgccgc
    14461 ccagggcgat ggccacctgc acgcctggtg gtacatccgg aagaacggcg tgtggcgact
    14521 gcggtaccgg ggtggcccgc aagtggtggc gaacctgctg gacacgctcg ccgctgacgg
    14581 ccgcatcacc ggctgggagc ccggcatcta cgaacccgag acgctcgcgt tcggcggccc
    14641 gcagagcatg gacgtcgcgc acgagctgtt ccaccgtgac agctgccatg tgctgtcccg
    14701 cgccgccgag cccggcccgg ccgcccgcca gcgggagacc agcatcctgc tgtgcgccgc
    14761 gctgatgcgc gccgccggac tcgactggta cgaggcgggg gacgtgtggg cacaggttgc
    14821 tgagcaccgc cccatcgacc cggccaaacc cgcttggcca ccggagcggg aaatcggcct
    14881 gcaggcggta atgcaccgcc tgctgacagc cgatgcccgt tccctgcccg ccctccctac
    14941 cgggtggctg gacgcgttcg aggaagccgg gcaatccctg gccagcctcg ctcaccaagg
    15001 gcggctccag cggggcctcc gcgcgatcct cgcccaccat gtgatctttc acgccaaccg
    15061 cgcgggcctc ccggtaacgg accagtcggc tatcgctgcc ctggccgtcc acaccgtgtt
    15121 cacccccgca gcagaccgca ttttcccagc tcagaaccta ttcccaaagg ctaaggtccc
    15181 acctatgaca ctcatcgatg atcagccgga cgtcaccccg gaagaactcc gcgacgccct
    15241 gaccgaccgc cttgtagccg ccggcacggt acgcaccccc tccgtcgagg ccgcgttccg
    15301 caccgtgccg aggcacctgt tcgtcccgag cgcctccctc gacgccgcgt acggcgacga
    15361 cccgatctac accaagcacg acggcgcggg tgtgtcactc agcgccgcgt ctcagccgac
    15421 gatcgtcggc atgatgctcg aacaactcaa cgctgagccg ggtcagcgaa tactcgaagc
    15481 cggggcgggc accggctaca acgccgccct catagccacg atcgtcggcc cccaggggca
    15541 cgtgacaacg atcgacgtgg acgacgacct cgtgaccggc gcccgcgacc acctggccgc
    15601 cgcgggcatc gggaacgtca ccgtcgtcct cgccgacggc gcgctcggcc accccgagaa
    15661 cgccccgttc gaccggttca tcgccacagt gggcgcgtgg gaggtcccgg ccgcgtggct
    15721 ggaccagctc actcctgaag gccgactcgt ggtcccgcta cgtctacgcg gcgtcgcctc
    15781 ccgtgcaatc gtgttcgaac gagacgagaa cggctggcac agcgtcgacc accagctcgc
    15841 cacgttcatg ccgctgcgcg gcatcggcga cgacgcccgc cgcaccgtcg ccatcaccgc
    15901 cgagcgggac gtcaccttgc aggtccacaa ggaccaggcc gccgacccca ccgagctcgc
    15961 cggcgtgctc gacaccaacc gcgtcgagac ctggaccgag gttacgatcc cggccacggt
    16021 ctcgtacgag ctgctggacc tgtggctgtg cctccgcctg gacaacccgc tcatgcggat
    16081 gcacgtcggc tcggaggcca ctacccgtgg caccgtgacc ccgatgttcc cctggggctc
    16141 catggcgacc accagcggca acagccttgc ttacctcatc tcccgctgta ccgccgaacg
    16201 tgacagcgcc gacgtgcccc tgtatgaggt cggcgtcgtc ggccacggcc ccagtggcgc
    16261 cgaactcgcc gagcacgtcg cgaacgagat ccgcacgtgg aaccaggact accgcgaccg
    16321 cgccgtgcgg ttcgagctgc ccgacacccc gccctccgct gaccccggca ccgggcggtt
    16381 cgtcctgtcc cggcccaccc acccgatcct cgtcacctgg gagtaacagt tgatggagcc
    16441 cacccaggca ttcgcgcggt tccccctcgt cgcccggccc cgcccggcct gcgccccgct
    16501 cgacgcccgg gtgggcaacc tgtgcgagct ggcccgcacc gccgaacgcg acagcgacac
    16561 gtcgacggcg tcgacagtgt tcaaccaggc cgccctcctg gccagcgatc tcggcctgcc
    16621 cgacctggcc cgcacctggt gtcaccagca cgccaccctg tacctgaccg cctgccccct
    16681 caccgggcgg gcggcccggc acgccgtcga acccctcgtg aacctcgccc ggctgcacat
    16741 ccgcgccggc gacggcgccc acgccttcgc tctcctggac ggcttgtacg aggctgcgca
    16801 agcgcgcacg gacaccaccg tcgacgagct ccacgtcccc ttctccatcc tcacccagac
    16861 cgtggcggat caccgggacg tcctccagtg gctttggacg gttcacctcg ctgacggcac
    16921 ccgcgccctc accggggcag gccgctggaa cgaggccctc gcccacctcc gcgctcgcaa
    16981 cggcgtcggc caccggatgc tcgacggccg acaggtcgcc gtcatcgccc acgccttggc
    17041 gggcgacacc gccaccaccc aggcgctgct cgacggcacc ccggcggggg agccctggga
    17101 agccgctgtc accgcctgcc tggccgccct ctgccggccc ggcgacgacc gtacggcagc
    17161 ggagatgctc acctgctacc gacgcctcga ccacacggcc cccggcctgg tggtgttccg
    17221 gacccggctc ggtctatcgg tggtcgacgc cgctggggga gtcgacaccg ccgacggccg
    17281 tgccgttgcc accacgctca tcatccgcgc ggtggcgacc gacgacggct acgccgcccg
    17341 agacgtactc gaccatcccg gatgcgcggc catactcaag gccgaccaga aggccgcgct
    17401 cacgcaatta ctgcaggcga gcggactcgg ctcccggcgt ttcccagagt ggctgatggt
    17461 ggagctgtcg gtcgccttgt cacggagcgg cgcggtgatc gcgcgcaacc tcaactcttg
    17521 cctcgtagac gccgagcgca tgggctagct gacggcgagc gggtaccagg cagcaccact
    17581 cacctcggac tcttaaatga gtcccacgtc cgcatctcta tctgtcaatg gtttcgagat
    17641 cggctgtcct aattgagaag tagtaccgcc tatgattcaa gcgtgcctga tatgtgatcg
    17701 cccacgaata ataggttcca taatggtgat gtgcgacctg ctcggatagg cctgtggctg
    17761 gccgcgcgtc ggcgctcgtt attgctattc attaaggagt tttgatcttc gaaaattctt
    17821 gctcgtcgtc tcggccgggt agatcgacag tgagcgtcac atatggcgaa gcccgttttt
    17881 cgggggtgac gagtggtcct atggaaagtt acttcgtccg agtggaaagc tgagcgcctg
    17941 tcgctggcaa tcgggatcgg cgtggctggc tggactgcga tactgggctg cttggccggg
    18001 tcggccgtgc catcttcccg ggagccgtgg tgcaatgcct caatatccgc tgaggtgcag
    18061 aagtactacg atgctgacaa gtggtgcgct ctgatcaaag aagaactcgc gaaagggcgc
    18121 atccctgact attggggcct actggagaag gccaggcggc agtcgatagc cgagacccca
    18181 aatgcgcctg cgcaaagacc tacggcgatg gagccgaaag ggcagagcgc caagggagcg
    18241 cgcggaccga gggatactcg gcccaggcca cgccccgatc cgcagccccg ccacaatccg
    18301 caggggcatg tccgtcactc gcttatcact gcaaaacctg ctacagacaa ggccgccgag
    18361 ccgagaaaga agcaggcaag taagtcctcg cgggcgtcct ctcctgctcg gggtcggcac
    18421 cagcgaacgt ccacctcctc gccggccccc gcgccgtcca cgccatacac gcggccagcg
    18481 ccttcacacg gagaacatgc ttccgtgggg cggccctcgg ggttgacggt tcacctggat
    18541 aggtccggtg ggacgagcgc cgccgccggg tgggctcacg ccgcttccgc cgtgttgttc
    18601 ggcgtcttcg tgatgacgat cagtgcggcc ctcatccagc ggtcccgcgt cctgacagga
    18661 ggcgctgtcg cgggagtacc cggagcgtcg cttccggttc cagtgattcc cgacgctgat
    18721 cccagcagtg agagcaaggc acccgctgag ccggtggaat cggcggctgc cactccggat
    18781 tctgcaatag aagcggccgg gcacggcgat gccaccgtcg atgccgacct cgggaaggcg
    18841 ggggagacgc cagccggaga ggttgtctcg acgcaggctg ccaccacctc gggactacag
    18901 ctcaggattc caccgtctgc gcttgtctcc ggacggctgt tcggaaggac tcgcctacag
    18961 gcagcggatc ggacggtgcg cttcacccgc gcggagggtc ggaatctgtt cgcgctgctg
    19021 gctaccacga aggacggcgt gcgacaggat ctcgttatcg aacacctgtg gcctgagcag
    19081 ggcgaacacg ggtcacagca cctggagacc ggggtccgtg acatcaacgc ggcgctgcgc
    19141 agtgcgaccg ggctgtctac cggagtgaag ttcgtgatca agactggcca gtgccggcac
    19201 cttgcctcgg ccttcttcga catcgacctg tggcggttcg agcaggcgcg tctggtggcg
    19261 aacacagcgc tggaggagga cacccgggtg caggcgctca ggcagatggt cgccatccat
    19321 gaagggccgc tactcgctga gcgagatgat ctctggtgcc tgccgctccg gcaggccgcg
    19381 gcccggaagg cgacgaacgc ggtgatgcgg ctggccgagc tggagcacaa gaccgacccg
    19441 gatcacgcac tggatctgct gactctcgct gtggaccgga tcgatcccta cagtgaggtc
    19501 ctgtggtgcc ggatcatgac cattcatggt gagctgggac ggctgccggc cgtacgcgcg
    19561 acctttcagc agctcaccga gcgactgcgg gaggtcgacg ccgagccgag ccgtcaggcg
    19621 aggcagatct accgggggct cgccgggtag cggcgagtaa tgacggaggt cctgaccaga
    19681 agccgggcca ggacctccct cggcgcggca atgggtgctg cttctcttct tgagggatcg
    19741 aggctacgcg ccgaggagta ctcggtcttg tctgctgtag gtggcccggg tctcgggggt
    19801 gaggagttgg gcggggcggg tgccgtaaat ctgcgcgagc agccgcagca catgtgctgg
    19861 tgggcggcgg ccggactcgg gccagctctc gtattcgtac agcctgctct cgcgtagcgg
    19921 agccgtcccc gtgcgctcca gggcattgaa cgtggcgacg acctgggcgg cggtgagacc
    19981 gacggcgtcg cggtagaggc gtagcggtgc gacatcgtgg tcgaaggaga gcacgacggc
    20041 gatctggtcg acagtgaagc cgtgtccgcg caggtggaag ccgcggcggc ggcactcgag
    20101 cagggtctgg tagcccttcc cggacatgat tactccccgt ctggtgatgt tcgctggccg
    20161 atcgggtgga ccgtagggcg ccttcctgcg agatctccag tcgatgtggg tgatccatct
    20221 gccggggtgt gatcgcctag ctctatggcg gtgtgttggc gcaggtcaac gcgcacttcg
    20281 gcgtggcggg cgacgggacg gccgtggggt tcgattcggg cgcggagtcg gttcatggtg
    20341 tgggcccctt cacgggaacg gccgggacga catggaggtg ccctgacgat gactggacgc
    20401 gagaacgcgg acgcgactgt gctggacgac ggcggacggg acggattccc tggcctgccg
    20461 ctcggccctg cactggtccg ccgatggtgg agtggacttg gcgggccgat gctgtggcgc
    20521 aggcgattcc acgggcgtga ggaccaggtc acggctgccc ggaagatggt gcgcctgctg
    20581 ctggaggaca cctcccgggc cgacgatgcc gagtggatca cggcagagct ggccgccaat
    20641 gccctgttgc actcacgctc gggcctgttg ggcgggctct tcatggtgga ggtgctgcgc
    20701 ggcctgcaca tggctcgtat caccgtctat gacctcggcg gcgaaggaac ccctgccgtc
    20761 caagcacgga agccggggca ggacatcggc gagcacgggc acggcctgcg tggagtacga
    20821 caactcgcca cacaagccgg ggtacgagga gatgcgacca ccgggcacgc ggtctgggcg
    20881 caactcgcct tgaactgcgg cgcgagcgca cggaccgcat gatgacctgg agcacgcgga
    20941 cccagcggcc ggactcgggc acaggaccag tgccggatgg tgaggaggca attcgtcgcg
    21001 ggctgcagga gttgcggagg gagttcccga actggggctt cctcgttatc cacaaggtgt
    21061 gggtcgcagt ccgggggaag accatcatgg tcaccgccga cacccccaag gggctgcgcg
    21121 ccggattgcc gcctgcgccc gctgaccccc ctgtcgtccc cgcgctggcc acgacgtggc
    21181 caatgacggc cgacgatgtc ctgccagggg acatgacatg ttcgcccacg gcggcgggtg
    21241 tgtgggccca tacagaggtt ccaccagtga cgacgcggcg ggctcggcag cccggacgcc
    21301 gtcgccgtgg ccgggcgagt gcttgacatc cggggtgaag gtgggcgtcg atgtcatgga
    21361 gcgatcgcag cgtgctgtag cggcacgctc gatggcgcgg gctcgggcac agggcgcggc
    21421 ggagacctaa ccccgctgcc ccggctctcc gggcgcggaa atccctgacg accgtttcgt
    21481 gcgcgaggcc gccaaggcac tcgacctttg cgctctggta gcggcggacg ggaggcggcc
    21541 tggggcacca gcggatttcg ctacgcgggt cgtttcatcc ccgggatgtt cgctggtgtg
    21601 ccccatgttg ccgctggcgt tgcgttcgct gtagccgctt ggaccgcatc gacgccgagc
    21661 cggtgttcgc accggtgaac ccgggtcccg gacgatgcgt tgcgtcgcca gactcgccct
    21721 acaggcgaca gaccaatatg tgcggcgccg tacggatgcg ggtcatctta atccgcggtg
    21781 gttcccgccg tacgtcgctt tccctctgta ccgggctggc cttggtcagg ccggcggccg
    21841 gaccgccggc cgaggcccat gggtgatgcc ccgccagctc gcccgtctgt gcgcttgcag
    21901 ccccagcttt gcctgcgtcg gccaggacgg ggatcgtctc cgccggggcc ggggtggttt
    21961 gccttggacg cgatgggtac ggcctccgca cgtgcccccg agggacctgc gggaagcggg
    22021 ccggtgttgg gggcggtaca ggcggcccca gcgagcttgg caatcctctc gccatgcgct
    22081 tgccctcgta ggcgatgatc tctagcgggc ggttgtcagc gcccgcttcg gtacgcatga
    22141 ccaggacatc gtcaccgctc cacatcagcg cccatccgtg gccgtaggcg tccagtccgc
    22201 gtacgtgcgc cgcgtccacc gtgatcgcgg cccattccat gcgtgcgccc ccttcggtcc
    22261 ctgtcgcacc gctgaatacg cgcggcggct atttagtgat gcgaatctat ggatgctcga
    22321 cggggccggt ccagtcaagt cgattcggca gctacttcat gactctttcg gcctcggctg
    22381 aaagattagg tagtgcatcc gtagtcttcg gtgaattcgc ctcaacggga cgacctgtct
    22441 gcattcgggt ttgaagccgc acctcggcaa ggcggatacc agcaggtgga ggagctcctt
    22501 gttaggtgat tctctccgaa acgggggccg ctgaaaaatg ttccgcgaca cgcttgcaac
    22561 gcgcgccgat gcgagcgatg gtcgagctcc acgaaatccg aaccggccaa acagcgggcc
    22621 ggtacacggc tggaaaggag ccttatcaat ggtcgctatc accgtcacgg aaaacgcgta
    22681 cggcatggac gcgaacgcaa tttccgccgc tcgcgacacg gacgacagtg ccccggacat
    22741 ccacaccggc actgcgctga acacccgtga ggaggccgtg tgggccgcgc tggccgccag
    22801 ccccggtacg tcggttgccc tgatcgcggg tgcggccgga atcagccgag tgacggcggg
    22861 aaagatcctc aatcagttcg aggccgaggg ccgcgcgagc cgtgtccccg gcggacacga
    22921 cgggcggggc cgtacccccg acctgtggta ccccgccgag gacacgaccg tctcggaggg
    22981 gaacgccccg gacgaggcct ctgactcgcc cgctgaggtg cccggcccgg atgacccgga
    23041 cgacccgaac gttcccgccg tgatggacat gtccgaggac gacggggacg gtgcggacga
    23101 ggaggaggcc accgctgcgg cggttcccgc aaccgatggc cagttcgacc aggctgaccc
    23161 ggagggcgtg gtctcggccg acgtggccgg tgacgacccc gtcccggaca gcggcgacgt
    23221 gggtcacgcc ctggacgaag cccttgactc acgcgctgac gcgaccgaca cggacacgga
    23281 cgttccggcc gacggttccg aggagacggc cgaggccgag gacccggcct gggcatgggc
    23341 gcggacggcc ctgctggagc tggccgacct gatcaccgga gcagtcgggg cgttcgacga
    23401 cgacggggac gcggtcacgg cgttgggccg gttggagatg gccatggcca aggctccgca
    23461 ggcacaccgc gacgcccgcg ccgtgttgac cggcaccaac ccctccggca ggggaacggg
    23521 cggacgtgtg agcaccggcg gcactacggg cgcgggtggg gctcgtcccg gtcatctgcg
    23581 tgacagggtg ctgtcccacc tgctcgacca cccggggaag gacttcaccc cgtacgagat
    23641 cggccgggta ttggagagct cgtccggcgc ggtcgccaac gccctggacc gcctggtcgg
    23701 tctcggtcag gccgagctga cctgcgagcg cccccgccgc tacgccctcg ccgtcaaccc
    23761 cgcccccggc gactgatggc ggcccggggt gggcctcccc gaggcggccc accccacagc
    23821 aacagccccg gtacctgggt ggacggccgg tatggccctc gcatcggccg cgacgtggcc
    23881 acggtgccgt cgctcacctg ccccgtttgg catccgtggc cagacgtccc aacgcgtccg
    23941 ggacaggccg tccgccctct ctgatcgccc gcctactcat ctgttcgttc ggtttcaccc
    24001 aacgccaagg aggcactgtc atggcccacg agatcgagat cttcgccgac gggtccgccg
    24061 gattcgccgc tgggatcaag cccggctggc accggcttgg ctacaccgcg cccggcccga
    24121 tgacggccga ggagctcctg gcccgcgccc agctcgccgc ctggaacgtc cgcaaggtgc
    24181 cggtcggcac ggtcaccgat ccggacaccg ggcggtccgt gaccgcagag gaggacttcc
    24241 tggtcgtccg taccaacccg gtcacgggtg agccggaacg gctcggcatg gtcggaaagg
    24301 actacaaggt cgtccaaaac gaggaggtcg ccgagttcct gcagaccctg gtcgacgagt
    24361 ctggagcgat cttcgacacg ggcggctcgc tgaacggcgg acggcgcgtg ttcgtcacga
    24421 tgcgcctgcc cgagccgctg atggtcggcg gattcgaccg ggtcgacctg tatctggcgg
    24481 cgttctcccg gcatgacggc tggggtgcgt tcaccacggt cgccacccct gtccgagtgg
    24541 tgtgtgcgaa caccgaacgc gccgcgctgc gaaaccacgc ctcgatgttc aaggtccgcc
    24601 acaccggcca tatcgcgggc cgtatcgccg aggcacgtga ggcgctgaag ctgacgtggc
    24661 ggcacggcga ggcattcgcc gccgaggccg agaggctgct cgcgacgccg atggacctga
    24721 aggagttccg gcagttcgcc gccgcacttc acccgatgcc cacagacgcg aaacccgtta
    24781 cccgccgcaa ctacgagctg gcgatgcgcc agctggagct gttgttcacg gacgcgccga
    24841 cgaacgagcc gatccgggga acccgctggg cggcctacaa cgcggtcacc gagcgtctgg
    24901 atcactgcag cccggtcatc ggccgccgcg aggccgagat cgtgcgggcc gagcgtgcgc
    24961 tgttggacga ccacgcccac tcgaagatca agacgcgggc gttccagatg ctcgctgcct
    25021 gatcgggcgt tcggcattcc caccctcccc cttgctcgtc cggtacggct cggcgcgggg
    25081 ccgtaccgga cccatccctg gaaaccgcac atcggttcgg gaccagcccg cgcaaccaca
    25141 gcaaggggcc tttccgcccc tcggatcacc gatcgaagga gaaactgtgg gcccgttcga
    25201 gcagatcgct atcgactacc tcatcgacgc cacccgcact ctggacgaag ccgccagccg
    25261 cttcgcgtcg gcatgggaga cgggggagtg cgttacggcc gaggacttgt cccgagccgc
    25321 cgtcgcgcaa caccttcgag actggtggca gcaggtcatg aaccagatcg acgccgatga
    25381 ggcggtcgac accgtgaccg cgatcatgga gagccgccgg gccgccgaag cgtacctgat
    25441 cagcgccagc cagctctcgt acggcgaatt gttcacccag gccatggccc aggcccgccg
    25501 tcaggccgcc cggcagttcc tggactccac ccggcatctc gccgaggcac tcaccggccc
    25561 caccgccgca ggccgctcgg tccccgccac cggctcggcc ggtggagagg tccgggcgtg
    25621 aacgcccctg caaaccagtc tccagaaagg acatggccca cgatgaacgt cggtaccgag
    25681 tccgccaccg gcgacgcagc gggcgaaccc gccggaggat ggcagctcgg cccactgcag
    25741 gagctcagcg ggcctccgcc acccgagcgc tccacgcttc caggcgctcc caccacggcc
    25801 accgccccga gcttcgcgga cacgttcgcc gggccggagg caccggacgg cggcgaagcc
    25861 gagaggctgg cggcccgggt tgctgaggtc gtcgctcacg ctcggcacgc cgactatgcg
    25921 gcatccgccg cgttggtctg tcagatccag cgcggtcacc agctcacctc cgagccgctc
    25981 tacagcgtgg tctactctca cgccctgcgc acctggtggg aacaggtccc ggctcagatc
    26041 agcgagaaca gtgtcgacgt cgtgcacgcc gtgcggcgag ttcgcgcgtg ggcgcggcac
    26101 cacctgaccg gcgaaccagc cgccgcgcgg ccgggcacgc tgttcgacca cgcgctcgcg
    26161 cacacctccc gggccgccgc ccgccacttc ctggccgcct cgggcgaact ccttgccagc
    26221 cgggcggacg ccgagacggc taccgctgag ccaagccagc accagaacgg ccgatgaggc
    26281 caaccggcct acctcaactc tgaccggctt cttctcggcc ggctgcctga agcacctcgc
    26341 agaaaggaac cgttcaccat gaccaccacc cgcgccgacg cgagccggga cgacaccgag
    26401 gcgttccgct tcctggcctg ggcctg
//
