LOCUS       NZ_VANP01000002        22877 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000002
VERSION     NZ_VANP01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 710028)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 710028)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2918
            Orig. end                         :: 25795
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22877
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22877
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22877
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12877](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12877)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            654..1394
                     /locus_tag="FED44_RS05165"
                     /old_locus_tag="FED44_05165"
     CDS             654..1394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656841.1"
                     /locus_tag="FED44_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05165"
                     /product="C4-type zinc ribbon domain-containing protein"
                     /protein_id="WP_111701607.1"
                     /transl_table=11
                     /translation="MKAAPEAQKRLLDLAELDTSLDRVRHRRRTLPDLAEIDELSKRLA
                     RLATQVIAAETEAGDLARDQAKAESDVDAVRVRVDRDTKRLDSGQVSSPKDLASLQSEI
                     TSLRRRQSDLEEVVLEIMERREAADAQVESLRSERDKVTGTLRAAEERRDAAFAEIDKE
                     AGELTGGRTAITADIPADLLALYEKLREQSGVGAAMLHGGRCLGCRTTLSIADLNRIRA
                     AAHDEVVRCEECRRILVRTAESGL"
     gene            1457..2920
                     /locus_tag="FED44_RS05170"
                     /old_locus_tag="FED44_05170"
     CDS             1457..2920
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF005567.0"
                     /locus_tag="FED44_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05170"
                     /product="bifunctional RNase H/acid phosphatase"
                     /protein_id="WP_138459943.1"
                     /transl_table=11
                     /translation="MTGGYVVEADGGSRGNPGPAGYGAVVKDEAGHVLAEAAESIGTTT
                     NNVAEYRGLIAGLESLLALGVEGARVEVRMDSKLVIEQMAGRWKVKHEGLRPLALEAAA
                     LARRLRVTWTWIPRERNTHADRLANEAMDAAARGETWRAGPATSAPWTPPPAGPAVGPG
                     TDPSDPGTLFPAPAPAPASDAGTGAPGGTASVERGARPADREARGTDSGGDRRARSAAG
                     AAVSSANWGGDAAGGVAGPGGAAAGGVAGPGGDAAGGLAGSGGVAVADDRRGHGWMPGA
                     TRTATSLLLLRHGQTPLSIEKRFSGLGDPELTPTGLAQAEAAAARLARGPRRVEVIVTS
                     PLARARQTAEAVASRTGSAVLVDEDLRETDFGAWEGYTFAEIQRRWPDELAAWLADPDV
                     APPGGESFASTARRVEEARERIVKAHESRSVVVVSHVTPIKTLIRFALGAPPEALYRMH
                     LDLACLSAIDYYADGPSVVRTFNDTAHLG"
     gene            complement(2863..4482)
                     /locus_tag="FED44_RS05175"
                     /old_locus_tag="FED44_05175"
     CDS             complement(2863..4482)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="FED44_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05175"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_138459944.1"
                     /transl_table=11
                     /translation="MTRRTARRRSLSLRGRLLLITLALLAAGLAISGAVAVATLRAHLI
                     ERVDQQLGPMATLLSRVPARLVTAPLTGQSRVPLSALPGMDLIDQVYLAYLRADGTVEQ
                     EGGPWLRGEGPELPRLDAAAVRRLGGRPFDARDDHGAAWRVVAAPRAALTSVGPREGPG
                     EGPRAGAAEVGTVVVAASLGGVRSTVGRLTLVCAATAAALMTSLAVIGWFAVRRGLRPL
                     RAIERTAAAIAAGDLSRRVPVPAAPHTEVGRLAAALNTMLAQLEAAFAGRERSQARMRR
                     FVADASHELRTPLFGIKGFAELHRMGGLPDVDHTLGRIESEAVRLVRLVEDLLLLARLD
                     EGEDALPMDLAPMDLRTLAADAHHDLRALDPARTVTLTGPDGGPAGAAPVRGDEARLRQ
                     VVSNLVGNAVAHTPPGTPVRIGVGTVGTGGGAEGVLVIADEGPGLPPEEAERVFDRFYR
                     LDGSRSRGGAGGAGLGLAIVRSIVAAHGGRVELRTAPGAGAAFRVVLPVHPATGAPTPP
                     GGWPQPRCAVSLNVRTTEGPSA"
     gene            complement(4479..5189)
                     /locus_tag="FED44_RS05180"
                     /old_locus_tag="FED44_05180"
     CDS             complement(4479..5189)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543644.1"
                     /locus_tag="FED44_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05180"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138459945.1"
                     /transl_table=11
                     /translation="MDGRRLLVVDDEPVVRELLAATLRFAGYTVTSAATGSQALEAAGA
                     EPPDLVLLDVMLPDMDGFEVIRRLRERPRPLSGDRPGQVPVLFLTARDTTQDKINGLRL
                     GGDDYVTKPFDLEELLARIEAVLRRAGAAPEDRTLRVADLELDPGGHQVTRAGVPVRLS
                     PTEFRLLHYLILNAGRVVSKAQILEHVWRYDFAGDTSIVDTYVSYVRRKVDKAGPKLIH
                     TMHGVGYVLRGPRP"
     gene            complement(5245..6018)
                     /locus_tag="FED44_RS05185"
                     /old_locus_tag="FED44_05185"
     CDS             complement(5245..6018)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_05185"
                     /product="hypothetical protein"
                     /protein_id="WP_138459946.1"
                     /transl_table=11
                     /translation="MTAYDVLRSEWGKFHSIRATLGCLAGALAATAAYGYLFGLADARR
                     YLAGSAADRAAFDPTDTGFRALVLAGVLVSAVGVLAVTSEYASGTMPVSVAAVPRRGLL
                     LGGKAAVVAVVTLVAGPSMALVSFTLSQLSLAARNVPSAGLGDPGVLGAVAGAGLFTGL
                     VGLYGVALGFLLRRSAGAVSLGTFLLILPGMASLFPDAMAEWIVVWWPSAAGARVFAVH
                     PGSGGLAPLAGIGVLAAAVLALLCAAAAVFRARDV"
     gene            complement(6015..6989)
                     /locus_tag="FED44_RS05190"
                     /old_locus_tag="FED44_05190"
     CDS             complement(6015..6989)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853290.1"
                     /locus_tag="FED44_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05190"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138459947.1"
                     /transl_table=11
                     /translation="MIEIRGLTKRYGDVTAVDGLSFDVRPGVVTGFLGPNGAGKTSTMR
                     MILGLDRPTSGSATIGGRRYADLPTPLREVGALLDAHAVHPYRSAGKHLLALARGNGIG
                     RRRVDEVLGLVGLADVAGRRPGGFSLGMKQRLGIAAALLGDPGVVLLDEPVNGLDPEGI
                     RWIRSLTRDLASEGRTVLLSSHLMSEMALTADHLVVVGRGRLLADTGLDAFVRSAARET
                     VVVRTPGARPLAALLEEAGATVRPGAGDELLVTGLSGATVGDVAGAHGIVLHELTPRRA
                     SLEEAYLELTGGSADFASAGARPATPAETQATTASMTTSGAAR"
     misc_feature    complement(7026..7046)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.97"
                     /tool="antismash"
     ncRNA           7183..7574
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="FED44_RS05195"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="FED44_05195"
                     /product="RNase P RNA component class A"
     gene            7183..7574
                     /gene="rnpB"
                     /locus_tag="FED44_RS05195"
                     /old_locus_tag="FED44_05195"
     CDS             7252..7386
                     /gene="allorf_010170_010304"
                     /locus_tag="allorf_010170_010304"
                     /protein_id="allorf_010170_010304"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVGNADPGRPAGQCHRKQTAPFAGVRVKRWCKRPPAPTVTWAAR"
     CDS_motif       7252..7320
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVGNADPGRPAGQCHRKQTAPFA"
                     /locus_tag="allorf_010170_010304_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       7321..7386
                     /prepeptide="core"
                     /locus_tag="allorf_010170_010304_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2399.9"
                     /monoisotopic_mass="2398.4"
                     /core_sequence="GVRVKRWCKRPPAPTVTWAAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVGNADPGRPAGQCHRKQTAPFA"
                     /leader_location="[7251:7320](+)"
                     /alternative_weights="2417.9"
     misc_feature    complement(7284..7296)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            complement(7688..8026)
                     /locus_tag="FED44_RS05200"
                     /old_locus_tag="FED44_05200"
     CDS             complement(7688..8026)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS05200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_05200"
                     /product="hypothetical protein"
                     /protein_id="WP_138459948.1"
                     /transl_table=11
                     /translation="MSTTVTDEQIRALAATAKPYSLALLQWGPERTMDGADAIELEHQR
                     RMVSLRAEGVIAILCPVASDTVAGVAIMTVPAEEAAEIMAGDPCVRAGMLRCEVNPCHG
                     FPGDALPL"
     gene            complement(8036..8479)
                     /locus_tag="FED44_RS05205"
                     /old_locus_tag="FED44_05205"
     CDS             complement(8036..8479)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013098.4"
                     /locus_tag="FED44_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05205"
                     /product="VOC family protein"
                     /protein_id="WP_138459949.1"
                     /transl_table=11
                     /translation="MTFVRRFDHVGITVADLDAATAFFVSLGLEADQKMAVEGEFLDTV
                     IGMTGARTEIVMLRAPGGGTTLELSSFTRPDHLPGSPAAPANELGLRNVAFEVHDLQAA
                     VHHAAAGGYGLVGGIGEYEGVWRMAYVRGPEGIIVSLAERIEK"
     gene            8568..9020
                     /locus_tag="FED44_RS05210"
                     /old_locus_tag="FED44_05210"
     CDS             8568..9020
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543499.1"
                     /locus_tag="FED44_RS05210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05210"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_138459950.1"
                     /transl_table=11
                     /translation="MQRTRFGEMACSIARTLDVIGEPWSPLILRDVWAGVRRFDHIQAD
                     LGISRKVLTERLNHLVEQGVLERLPYDARPRYEYHLTAKGVDLVEMLMAMARWGDRWLA
                     GEAGPPVLYRHHACGQIGHVEPRCSHCGEPMHADDVDLLPGPGSAG"
     gene            complement(9047..9703)
                     /locus_tag="FED44_RS05215"
                     /old_locus_tag="FED44_05215"
     CDS             complement(9047..9703)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017537588.1"
                     /locus_tag="FED44_RS05215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05215"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_138459951.1"
                     /transl_table=11
                     /translation="MDLFARSWTALRRAVAQLPDEAFAQRSGCTGWLVRDLVCHLVIDA
                     QDVLITLATPAETEPTRDAVTYWEVATTPPTGDDPLDALTVRLAAAYEEPRLLKFHLDD
                     VGSAAGRAAELADPDLRVGTRGEVLTVDAYLSAYVMEWTLHHLDLVAHLADAAGPPAEG
                     LARSREMLEKIAGSAFPSSFSDRDALLVGTGRRAPTDAERTELGELATRLPLVLG"
     misc_feature    9796..9811
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.5"
                     /tool="antismash"
     gene            complement(10001..12877)
                     /locus_tag="FED44_RS05220"
                     /old_locus_tag="FED44_05220"
     CDS             complement(10001..12877)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="FED44_RS05220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05220"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_138459952.1"
                     /sec_met_domain="DUF4135 (E-value: 3.4e-79, bitscore:
                     261.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.9e-38, bitscore:
                     126.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGDFDPSLDFLTAPALAGLSATLGSIPGLTEAEARLICQSTAEA
                     LEETVRLKVNRVLLLELNAARISGRLTGETPQLRWQEWKATAATPEFWLSLTGHYPTML
                     SRLGTIIDNRCAAAVELARRFAADRAALTTLPGGLRGELVGVDFGAGDSHRGGHSVVVL
                     HGSQGKVVYKPRSLAVDEALARLIDRLAPQLPAGSRIRVPDVLIRQGYGWAEHIQHTYC
                     ADETELRSFYRGVGHWLALMRLIGGSDLHMENLIAAGPAPVVVDCETLFTPHVPAKPSG
                     YGDAVDQATDLLSGSVLRTGLLPGRGVSLAWRGVDMSAVGGLPGQQPYTQVPVVVDAGT
                     DMARLGMERVELGAVSNHPSPDPILVHYWDLVLSGFTELAEHLDMLDRRGELAGLLTDF
                     ADRPIRVVLRATEAYAELARMLWHPASLHDEPTAMGKAAGLLAQHAENLPGAPSDPEVI
                     DAEVAELLVGDIPFFATTPARGRLDGPGGTSYGDEQDLIADALRRWRDRDAALDREVIR
                     SALVSAYLNEGWMPANKRMTVPLIQHQDLERRRRRIAAGIARSMLDTAVRGDDGTVTWT
                     APVLTSDGWFVQSLSPDVYGGAYGVAITLAAYVSETGQGRADEVPGLDGLLADLLHTIR
                     LAEERDAEARRTGPRRRPATPGGYVGIGSQIWSWLLLRRLGTVGSEEAVAQAGALAGQL
                     PEAVAADGVYDLLTGMAGAIVPLLRLSEQTGDQQWSVQADRIGERLLSLAHIDDRGARW
                     PSTAFPQGLGGVSHGATGIAWALARLADSATAGAADFRALADRAFLYEESLYDPAEKGW
                     RDLREMDDHRVTSSAWCHGAAGIGLVAADRLAREGAPRWADVLRRAAASSWSRGIGWNH
                     TLCHGDLGTWEIVRHAIDVGVGPEELTPEYLAAYVIGSMDEHGPVSGLSRDAFSPGLMP
                     GVGGMLYQLLRLHPDTSLPSVLLPDPEN"
     misc_feature    complement(10592..10594)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12897..13082)
                     /locus_tag="FED44_RS05225"
                     /old_locus_tag="FED44_05225"
     CDS             complement(12897..13082)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.3"
                     /locus_tag="FED44_RS05225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05225"
                     /product="DUF6229 family protein"
                     /protein_id="WP_111701617.1"
                     /transl_table=11
                     /translation="MPLTLDRSEEIVSAWRSGADVEGWDSPAGPLFIGEYAESEITLTA
                     LDTRLASSCTCSRFCC"
     CDS_motif       complement(12996..13082)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPLTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /locus_tag="FED44_RS05225_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(12897..12995)
                     /prepeptide="core"
                     /locus_tag="FED44_RS05225_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="3357.8"
                     /monoisotopic_mass="3355.6"
                     /core_sequence="PLFIGEYAESEITLTALDTRLASSCTCSRFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPLTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /leader_location="[12995:13082](-)"
                     /alternative_weights="3375.8"
                     /alternative_weights="3393.9"
                     /alternative_weights="3411.9"
                     /alternative_weights="3429.9"
     gene            complement(13137..13328)
                     /locus_tag="FED44_RS05230"
                     /old_locus_tag="FED44_05230"
     CDS             complement(13137..13328)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.3"
                     /locus_tag="FED44_RS05230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05230"
                     /product="DUF6229 family protein"
                     /protein_id="WP_208758842.1"
                     /transl_table=11
                     /translation="MPVTLDRSEEIVSAWRSGADVEGWDSPAGPLFIGEYAESEITLTA
                     LDTRRPSSCTGANTIPCC"
     CDS_motif       complement(13242..13328)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPVTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /locus_tag="FED44_RS05230_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13137..13241)
                     /prepeptide="core"
                     /locus_tag="FED44_RS05230_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="3486.9"
                     /monoisotopic_mass="3484.7"
                     /core_sequence="PLFIGEYAESEITLTALDTRRPSSCTGANTIPCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPVTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /leader_location="[13241:13328](-)"
                     /alternative_weights="3504.9"
                     /alternative_weights="3523.0"
                     /alternative_weights="3541.0"
                     /alternative_weights="3559.0"
                     /alternative_weights="3577.0"
     misc_feature    complement(13379..13388)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     misc_feature    complement(13413..13433)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.79"
                     /tool="antismash"
     misc_feature    13787..13796
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    complement(13787..13801)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.91"
                     /tool="antismash"
     misc_feature    13789..13802
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            complement(13888..14739)
                     /locus_tag="FED44_RS05235"
                     /old_locus_tag="FED44_05235"
     CDS             complement(13888..14739)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.4"
                     /locus_tag="FED44_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05235"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_167521399.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.7e-09, bitscore:
                     31.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDERIVEIAGDEGSSPGRYMQYVFDAGTGTYLRPADSEQMLAFRE
                     RGVKAAYLQAQAGAEFDADALERAWPEIWRELTRKRPEPTPEYYAVLDTGLLSRHPLLR
                     GLIVDGTNLTTEPDGEDANGHGTMVALILAAGLTRRPRLLNVKVADGNGRATPRDLVKG
                     IEWVRDFARRTSSPVCVNISLGCYSRRWGLFACDGTCDVCEAAVAAAGDVRVMTVAAGN
                     EPNRTTCPAMAGLRGRADNIFAVAQLGWDRSGVGTVAMPAGMQWIPYEEDGDLTTKAPD
                     RE"
     misc_feature    complement(14035..14037)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(14768..15082)
                     /locus_tag="FED44_RS05240"
                     /old_locus_tag="FED44_05240"
     CDS             complement(14768..15082)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS05240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_05240"
                     /product="hypothetical protein"
                     /protein_id="WP_138459955.1"
                     /transl_table=11
                     /translation="MLIITGLLLAVAGAVVAILGLGGVVEFKGEVAGAKAETTSVGLAV
                     LVVGALLAGIVAVKLPAQVNVLGDGGRRGFTEWFSEFGVRLCALLVAAGVVLLIVSLLV
                     "
     misc_feature    15309..15322
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.63"
                     /tool="antismash"
     gene            complement(15314..16063)
                     /locus_tag="FED44_RS05245"
                     /old_locus_tag="FED44_05245"
     CDS             complement(15314..16063)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS05245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_05245"
                     /product="hypothetical protein"
                     /protein_id="WP_138459956.1"
                     /transl_table=11
                     /translation="MTGDLLRAGLAATASAPTQPALDYYVIAPEAGAGAVRAEGLVVEE
                     FVFTGDHRTIGLNTAGWSGDDRAWWSSAAFGRAMREDPELRVRVVAVGRTDAEAAYRRL
                     GGGELPGEATLRDRFRDTLALPDSAPLRLGPEEGSGGFHDSRTYRVLFAGDLRLSGLAR
                     LAPEVVTLAGDADDPRTRIAGTGGLRTARDEFTWELRRIGPGVACCVDLTARLGTTSDD
                     ALRPLLRNLTTAIRHAGPIPVTIERFS"
     gene            complement(16266..17267)
                     /locus_tag="FED44_RS05250"
                     /old_locus_tag="FED44_05250"
     CDS             complement(16266..17267)
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019352.4"
                     /locus_tag="FED44_RS05250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05250"
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="WP_138459957.1"
                     /transl_table=11
                     /translation="MTEVGRGTTRSTFSRRAFTTAATAAAIAPLVVSAQADAAPVGRNA
                     TAPVRLGNPRRITLYVENLPNGDMGYGLEPGKATIPGPLIEMVEGETLEVELVNNADVT
                     ASLHVHGVDYETSSDGTRMNDSVVEPGARRVYVWRTHAPGRRPGGTIEPGSAGYWHYHD
                     HVVGTDHGTGGIKKGLYGPLVVRRKGDVLPDKTFTVVFNDVRINNLPAGPHFLAKIGER
                     VEFIVITHGSAFHTFHIHGHRWADNRTGLLESPQDPSRIIDTKTTGPAESFGFQVVAGE
                     RVGPGMWMYHCHVQSHSDMGMAGVFMVSDEKGNVPGGHDMGGGSGGGMDMSH"
     CDS             17307..17483
                     /gene="allorf_020225_020401"
                     /locus_tag="allorf_020225_020401"
                     /protein_id="allorf_020225_020401"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MATGRRRGRASRRDAGAGPRARSGPGTRRDETGARCFPPHRATLL
                     MELGDSGRGKSIS"
     CDS_motif       17307..17408
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MATGRRRGRASRRDAGAGPRARSGPGTRRDETGA"
                     /locus_tag="allorf_020225_020401_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       17409..17483
                     /prepeptide="core"
                     /locus_tag="allorf_020225_020401_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="2556.9"
                     /monoisotopic_mass="2555.3"
                     /core_sequence="RCFPPHRATLLMELGDSGRGKSIS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MATGRRRGRASRRDAGAGPRARSGPGTRRDETGA"
                     /leader_location="[17306:17408](+)"
                     /alternative_weights="2575.0"
                     /alternative_weights="2593.0"
                     /alternative_weights="2611.0"
     CDS             complement(17505..17639)
                     /gene="allorf_020423_020557"
                     /locus_tag="allorf_020423_020557"
                     /protein_id="allorf_020423_020557"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPCAVTRHALPSGSRIAVEPAAWTTECDGATTERSPLTSLQSGM"
     CDS_motif       complement(17574..17639)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPCAVTRHALPSGSRIAVEPAA"
                     /locus_tag="allorf_020423_020557_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(17505..17573)
                     /prepeptide="core"
                     /locus_tag="allorf_020423_020557_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="2227.4"
                     /monoisotopic_mass="2226.0"
                     /core_sequence="WTTECDGATTERSPLTSLQSGM"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPCAVTRHALPSGSRIAVEPAA"
                     /leader_location="[17573:17639](-)"
                     /alternative_weights="2245.4"
                     /alternative_weights="2263.4"
                     /alternative_weights="2281.5"
                     /alternative_weights="2299.5"
                     /alternative_weights="2317.5"
                     /alternative_weights="2335.5"
                     /alternative_weights="2353.5"
     gene            complement(17690..17974)
                     /locus_tag="FED44_RS05255"
                     /old_locus_tag="FED44_05255"
     CDS             complement(17690..17974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887056.1"
                     /locus_tag="FED44_RS05255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05255"
                     /product="YiaA/YiaB family inner membrane protein"
                     /protein_id="WP_111701634.1"
                     /transl_table=11
                     /translation="MTKPVKSTTTTAFYLQAVISFAISLAGLAAGILYLPVTTWVRSFL
                     ALGLMYVVTSTFTLAKCVRDRQEEATVVSRVDQARLDKLLAEHDPFRTD"
     gene            complement(18154..18711)
                     /locus_tag="FED44_RS05260"
                     /old_locus_tag="FED44_05260"
     CDS             complement(18154..18711)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014505.4"
                     /locus_tag="FED44_RS05260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05260"
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_138459958.1"
                     /transl_table=11
                     /translation="MLWVALLIVAVLIVLAALAGTGRARQASRGPARGTSRRRPAPRSP
                     GATTRPSRGARPSSPPSSRTTRGETRTGAAGERTGPQPGEIWWADVPYEDGPGHKVRPC
                     VVLRTYHGGAEVLKITSQDRSDRSDHVEIPTRTWDPSADHNSFLDLTGPVRVPSASFDD
                     RAGTLDPRVWRQVCRLHEISPN"
     gene            complement(18976..19986)
                     /locus_tag="FED44_RS05265"
                     /old_locus_tag="FED44_05265"
     CDS             complement(18976..19986)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132551.1"
                     /locus_tag="FED44_RS05265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05265"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_138459959.1"
                     /transl_table=11
                     /translation="MKILVIGGSVFLGRAIVEEALRRGHEVTTFNRGRSGTDLPGVEAV
                     RGDREVTGDLRRLTDGRRWDAVVDVCGFVPRVVLESVRALSGHASHYTFISSISAYPDW
                     PDKTGVDETFPTHECPADADAEFGDYGVLKAGCERAVEEHFDGAALVVQPGLILGPHEN
                     VGRLPWWLDRISKGGRVLAPGNPAQPIQLIDARDIAAFTLDQAAGGTTGRYMTGGVPGR
                     ATFGSWLGDCVEATGSGAELVWADDDFLTAQGVEPWTELPLWYPGADGLGVWNHSSAKA
                     LAAGLTCRPLRETVRDTWEWLKDIPEERRSFRGVRVGSGIDPDKERRVLAAWDAR"
     misc_feature    19971..19985
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(19972..19987)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.16"
                     /tool="antismash"
     misc_feature    complement(19974..19992)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.65"
                     /tool="antismash"
     gene            complement(20141..22441)
                     /locus_tag="FED44_RS05270"
                     /old_locus_tag="FED44_05270"
     CDS             complement(20141..22441)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015116 - sulfate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852038.1"
                     /locus_tag="FED44_RS05270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_05270"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_138459960.1"
                     /transl_table=11
                     /translation="MTISDGTISHRDWKSVLRHDVPASLVVFLVAVPLSLGIAVASGAP
                     VAAGLVAAVVGGVVAGALGGSVVQVSGPAAGLSLVVAELVHTYGWRATCAITAMAGLLQ
                     VGLGALRVARAALGVSPAVVHGMLAGVGAVIALSQLHIVLGGSPQRSALENVLELPAQI
                     VHNHTHAVLIGVLTITVLLVWGRIPRLRAVPAPLAALMIATLTAGVSGWDLTKVDLRGG
                     FSSVQGPLAPQGDWHAIAGAVLLVALLAGVESLLTCVASNRLHDGPRADLDRELTAQGV
                     ANVVSGVLGGLPVAGVVVRTTTNARAGARSRWSTVLHGVWVLLFTAAFAWMLALIPLEA
                     LAALLLFIGVQMVNLGHVRNLRNHREVPVYAVTMAGVVLIGLAEGVAIGLGLAALLALR
                     RLAWVSVDVRQDGERHWRVVVTGSLTFLGVPRLTEALRAIPAGSAVELDLHLDFMDNAA
                     FEALHTWRLEHERAGGEVDVDEPHGEWYAAAISGARLFPARIPPRHDRWWLPWAYRRRA
                     HSAGAHSAGPGPYGSFEVIGADGDSAAGHDDAVICEPQGVPDLLEGTREFHRRTAPMVR
                     PLLTRMARGQSPSHLFITCADSRIVPNIITASGPGDLFTVRNIGNLVPRAGAVPPDDSV
                     AAAVEYAVNVLEVRMITVCGHSGCGAMAALLGEVPDLPALRAWLRHGRQSLARFVAAGP
                     GQDADDAGPLDRLCRVNVIQQLDNLRTHPFVDTLVRAGRLELTGLYFDIGAARVHVLEQ
                     ERFTPVPELRTTG"
ORIGIN
        1 tccgctctat ctgcgcggca ccacgagcgt cgccgcgacc acgttcaagg gccgggtcgt
       61 ccaccggctc atccgcggcg gcgccgcgct gtacgccgcg cacaccaacg ccgacgtggc
      121 cgatccgggc gtctcggacg cgctcgcgcg ggccgtcggc ctcgcgggtg agctgcggcc
      181 actccagccc gccgcggacg atccgcgccg ggggctcggc cggatcgggg acctgcccgc
      241 cccgatgccg ctgcgggagt tcgccgcgct ggccgccgcc ggactgccgc gtacggcggc
      301 tccgctccgc gtcgcgggcg acccggacca tacggtgcgg accatcgccg tctgcggcgg
      361 cgccggcgac tccctcctgg gcacggcccg ggcggcgggg gtggacgtct tcctgacggc
      421 cgacctccgg caccaccccg ccggtgagca cctggaggcg ggcgggcccg cattggtcga
      481 cgcctcccac tgggccaccg aatggccgtg gctcgccgac gccgccgagc gtctgacgtc
      541 agcgttggcg gcagggggca ttactgttga ggcgcgcgtc tcgggcgccg tcaccgacgc
      601 ctggacggcg acgaccaccg acttggaccc ccgagcatct tgagggattt gggatgaagg
      661 ccgcaccgga agcacagaag cgtctgctcg atctcgcgga gctcgacacc agtctcgacc
      721 gggtgcggca tcgccgccgc accctgcccg acctggccga gatcgacgag ctgtccaaga
      781 ggctcgcacg gctcgccaca caggtcatcg ccgccgagac cgaggccggc gacctcgccc
      841 gcgaccaggc caaggccgag tcggacgtgg acgccgtacg cgtccgggtc gaccgcgaca
      901 ccaagcgtct cgactccggg caggtctcct cgcccaagga cctggcgagc ctccagtccg
      961 agatcacctc gctgcggcgc aggcagtcgg acctggagga ggtcgtcctg gagatcatgg
     1021 agcgccggga ggcggcggac gcccaggtgg agtcgctcag gtcggagcgc gacaaggtca
     1081 ccgggacgct gcgggccgcc gaggaacggc gtgacgcggc cttcgccgag atcgacaagg
     1141 aggccggcga gctgaccggc ggccggaccg cgatcaccgc cgacatcccc gccgacctgc
     1201 tcgccctgta cgagaagctg cgcgagcaga gcggcgtcgg cgccgccatg ctgcacggcg
     1261 gccggtgcct cggctgccgt acgaccctgt cgatcgccga cctcaaccgg atcagggccg
     1321 ccgcccacga cgaggtggtc cgctgcgagg agtgccgccg gatcctcgtc cgcacggccg
     1381 agtccgggct gtgacatcgg ctgcgtgaac gagggtgtgc ggatgacgag ggcgtgcggg
     1441 tgacgggggt gcgtggatga ccggggggta tgtcgtcgag gccgacggcg ggtcgcgggg
     1501 caaccccggc ccggccgggt acggcgcggt ggtcaaggac gaggccgggc acgtgctcgc
     1561 cgaggcggcc gagtcgatcg gcaccacgac aaacaatgtg gccgagtacc gcggcctgat
     1621 cgccgggctc gagtcgctgc tcgccctcgg cgtggagggc gcgcgggtcg aggtgcggat
     1681 ggattccaag ctggtcatcg agcagatggc cgggcgctgg aaggtcaagc acgaggggct
     1741 gcgcccgctc gccctggagg cggcggccct ggcccggcgc ctgcgcgtca cctggacctg
     1801 gattccgcgg gagcgcaaca cccacgccga ccgcctcgcc aacgaggcga tggacgccgc
     1861 ggcccggggg gagacctggc gggcggggcc ggccacctcc gccccgtgga ccccgccccc
     1921 tgccgggccc gccgtgggcc cgggcaccga cccgtccgac cccggcacgc tcttccccgc
     1981 ccccgccccc gcacccgcgt cggacgccgg caccggtgcc cccggcggga ccgcatccgt
     2041 ggaacgcggt gcgagacccg cggatcgcga ggctcggggc acggactccg gcggtgaccg
     2101 gagagctcgg agcgcggccg gcgccgctgt ttccagcgcg aattggggcg gggacgctgc
     2161 aggtggcgtc gcgggtcccg gcggtgctgc cgcggggggc gtcgcgggtc ccggcggaga
     2221 cgccgcgggc ggcctggcgg gttccggtgg agtcgccgtg gccgacgatc ggcgcgggca
     2281 cggatggatg cccggggcca cccggaccgc cacgtcgctg ctgctgctcc ggcacgggca
     2341 gacgccgctc tcgatcgaga agcggttctc cgggctcggc gacccggagc tcaccccgac
     2401 cgggctggcg caggccgagg ccgccgccgc acgcctggcc cgcgggccgc ggcgggtgga
     2461 ggtgatcgtc acctccccgc tcgcccgcgc ccggcagacg gcggaggccg tggcgtcccg
     2521 tacgggttcg gcggtgctcg tggacgagga cctgcgcgag accgacttcg gggcgtggga
     2581 ggggtacacg ttcgcggaga tccagcggcg ctggcccgat gagctggccg cctggctggc
     2641 cgaccctgac gtggcgccgc cgggcggcga gagtttcgcc tcgacggccc gcagggtcga
     2701 ggaggcgagg gaacgcatcg tcaaggccca cgagagccgc agcgtcgtcg tggtctccca
     2761 tgtgaccccg atcaagacgc tgatccgctt cgccctgggc gcgccgcccg aggccctcta
     2821 tcggatgcac ctcgatctgg cctgcctgtc ggcgatcgac tactacgccg acggtccttc
     2881 cgtggtgcgg acgttcaacg acacggcgca ccttggctga ggccacccgc ccggaggagt
     2941 cggcgcgccg gtcgccgggt ggacgggcag gacgacgcgg aaggccgccc cggcgccggg
     3001 cgcggtccgc agttccaccc gcccgccgtg ggcggcgacg atcgaccgga cgatggccag
     3061 tccgaggccg gcccctcccg cgccgccgcg gctgcgtgat ccgtccaggc ggtagaagcg
     3121 gtcgaagacc cgctcagcct cctccggcgg cagtcccggc ccctcgtcgg cgatcaccag
     3181 gacgccttcg gcgccgccgc cggtaccgac cgtgccgacg ccgatcctca ccggggtgcc
     3241 cggcggcgtg tgggcgactg cgttgcccac caggttggag accacctgcc gcagccgcgc
     3301 ctcgtcgccg cgtaccggcg cggcgccggc cgggcccccg tcggggccgg tcagcgtgac
     3361 cgtccgggcg ggatcgagcg cgcggaggtc gtggtgcgcg tcggcggcga gcgtccgcag
     3421 gtccatgggc gcgaggtcca tcggcagggc gtcctcgccc tcgtcgaggc gggccagcag
     3481 gagcaggtcc tccacgagcc ggaccaggcg caccgcctcg ctctcgatcc ggccgagggt
     3541 gtggtcgacg tcgggaaggc cgcccatccg gtgcagttcc gcgaatccct tgatcccgaa
     3601 gagcggcgtg cgcaactcgt ggctcgcgtc ggcgacgaac cgccgcatcc gggcctgcga
     3661 ccgctcccgc ccggcgaacg ccgcctccaa ctgggcgagc atcgtgttga gcgcggcggc
     3721 cagccgcccg acctcggtgt gcggagcggc gggcacgggc acccgccggg acaggtcgcc
     3781 cgcggcgatc gccgccgccg tccgctctat cgcgcgcagc ggccgcagcc cccggcgtac
     3841 ggcgaaccag ccgatgacgg cgagcgacgt catgagggcg gcggcggtcg cggcgcagac
     3901 gagcgtcagg cggccgacgg tcgacctgac cccgccgagg gacgcggcca cgacgacggt
     3961 gcccacctca gccgcacccg cacgaggccc ctcgccaggc ccctcacgag gccccacgga
     4021 ggtgagagcg gcccgggggg cggcgacgac ccgccacgcg gcgccgtggt cgtccctcgc
     4081 gtcgaacggc cgcccgccca gccggcggac cgccgcggcg tcgagccggg ggagctccgg
     4141 gccctctccc cgcagccagg ggccgccctc ctgctcgacg gtcccgtccg cccgcaggta
     4201 cgccaggtac acctggtcga tcaggtccat gccgggcagg gcgctcagcg gcacccggct
     4261 ctgcccggtg agcggggccg tcaccagccg ggcggggacc cgcgacaaca gcgtcgccat
     4321 cggcccgagc tgctggtcca cccgttcgat gaggtgggcc ctgagcgtgg cgacggcgac
     4381 cgcgccgctg atcgcgaggc ccgccgcgag cagggccagg gtgatcagca ggaggcgtcc
     4441 ccgcagcgac aggctcctcc ggcgtgccgt ccggcgggtc acgggcgcgg cccgcgcagg
     4501 acgtagccca cgccgtgcat ggtgtggatc agtttcggcc cggccttgtc gaccttccgc
     4561 cgcacgtagc tcacgtacgt gtccacgatg ctggtgtcac ccgcgaagtc gtaccgccag
     4621 acgtgctcaa ggatctgcgc cttggagacg accctcccgg cgttgaggat caggtagtgc
     4681 agcaggcgga actcggtcgg cgacagccgt acgggaacgc ccgcccgagt cacctggtgg
     4741 ccgccggggt cgagttcgag gtcggccacc cgcagcgtgc ggtcctccgg ggccgccccg
     4801 gcccgcctga gcacggcctc gatccgggcg agcaactcct ccaggtcgaa gggcttggtc
     4861 acgtagtcgt cgccgcccag ccgaagcccg ttgatcttgt cctgggtcgt gtcgcgcgcg
     4921 gtgaggaaca ggacgggcac ctgtcccgga cggtcaccgg acagcgggcg ggggcgttcc
     4981 cggagacgcc ggatgacctc gaacccgtcc atgtcgggca gcatgacgtc gaggaggacg
     5041 agatcgggag gctcggcccc cgccgcctca agggcctgcg acccggtcgc ggcggaggtc
     5101 accgtgtatc ccgcgaagcg cagcgtggcc gccagcagtt cccgcaccac gggctcgtcg
     5161 tcgaccacga gcaggcgccg cccgtccact ccggcctccc ttcgtcagcg gcaggatagg
     5221 tccgccgtcc aggatcacgt gccttcagac gtcccgtgcc cggaagacgg cggcggccgc
     5281 gcacagcagc gcgagcacgg cggcggccag caccccgatc cccgcgagcg gggcgagccc
     5341 gccggacccc ggatggaccg cgaacacccg cgcgcccgcc gcgctcggcc accagacgac
     5401 gatccattcg gccatcgcat cggggaacag ggacgccatg ccgggcagga tcagcaggaa
     5461 cgtcccgagc gagacggcgc ccgccgacct gcgcaggagg aacccgagcg ccacgccgta
     5521 cagtccgacc agccccgtga acagtccggc gcccgcgacg gccccgagca cgcccgggtc
     5581 gccgaggccc gcgctcggca cgttccgcgc ggccagcgag agctggctca gcgtgaacga
     5641 caccagcgcc atcgacggcc cggcgacgag cgtgaccacc gcgacgacgg cggccttgcc
     5701 gccgagcagc aggccccgcc tgggcacggc ggcgacgctg accggcatcg tccccgaggc
     5761 gtactccgac gtcacggcga gcacgccgac cgcgctgacg agcacccccg cgagcacgag
     5821 agcgcggaag cccgtgtcgg tggggtcgaa ggccgcccgg tccgccgccg acccggccag
     5881 ataccggcgg gcgtcggcca gcccgaagag gtacccgtac gccgcggtcg ccgccagggc
     5941 cccggccagg cagccgagcg tcgcccggat gctgtggaac ttgccccatt ccgaacgcag
     6001 gacgtcgtac gcggtcatcg ggcggctccg ctggtggtca tggatgcggt ggtggcctgg
     6061 gtttcggcgg gggtcgcggg ccgggcgccg gccgaggcga aatcggcgct gccgccggtg
     6121 agttcgaggt acgcctcctc cagggaggcc cgccgcggtg tcagttcgtg caggacgatg
     6181 ccgtgcgcgc cggcgacgtc gccgaccgtg gcgccggaca gccccgtcac cagcaactcg
     6241 tccccggcgc cgggccgtac ggtcgcgccg gcctcttcga gcagggcggc gagcggccgc
     6301 gcgcccggcg tgcggaccac gaccgtctcc cgggccgcgg accgtacgaa cgcgtcgaga
     6361 ccggtgtccg cgagcagccg cccgcggccg acgacgacca ggtgatcggc ggtgagcgcc
     6421 atctcgctca tcaggtggct ggagagcagg acggtgcggc cctcggaagc cagatcgcgc
     6481 gtcaaggagc ggatccagcg gatcccctca gggtcgagcc cgttgacggg ctcgtcgagc
     6541 agcacgacgc cgggatcgcc gagcagcgcc gccgcgatgc cgaggcgctg cttcatgccg
     6601 agggagaacc cgcccgggcg acgccccgcg acgtcggcca gtcccaccag tccgagcacc
     6661 tcgtccaccc ggcgccggcc gatgccgttg ccgcgggcca gggccagcag gtgcttcccg
     6721 gcgctcctgt acggatgcac ggcgtgcgcg tcgagcagcg cgcccacctc gcggagcggc
     6781 gtgggcagat cggcgtagcg ccgtccgccg atcgtggcgc tcccgctcgt cggccggtcg
     6841 aggccgagga tcatccgcat cgtgctcgtc ttgcccgcgc cgttcgggcc gagaaagccg
     6901 gtgacgacgc ccggccgtac gtcgaagctc agcccgtcga cggccgtgac gtcgccgtag
     6961 cgcttggtca gtccgcgtat ctcaatcatg cgcagcaggc tggcccaccc gtcttggcgt
     7021 tccgggagag agcctgtgag atctctgtga gcggtccccc cgttgcctgc gccgctgccg
     7081 ccggcccgcc cgccccgggt ggagaactcg cagaatcctc acatgacttc cggccgtgcc
     7141 ggggaacgga gccggagccg ataggcttgt cctcacggcg gacgagccgg ccgggcggcc
     7201 gcgtcagggc ctcgcgccct gccgaggaag gtccgggctc cacagggcag ggtggtcggt
     7261 aacgccgacc cggggcgacc cgcgggacag tgccacagaa aacagaccgc ccccttcgcg
     7321 ggggtaaggg tgaaacggtg gtgtaagaga ccaccagcgc ccacggtgac gtgggcggct
     7381 cggtaaaccc cacccggagc aaggtcaaga aggggcgttc tccggaacgt cccgcgcgcg
     7441 acgttcgagg gctgcccgcc cgagccgcgc gggtagaccg cttgaggccg ccggcaacgg
     7501 cggtcctaga tggatggccg ccggtcagcc cccgtggctg accacagaac ccggcctaca
     7561 ggccggctcg tccaccttca cacccctgac cacggccttg gggcggacca ggtgccgctg
     7621 ttcaaacccg gcagtgaccc gtcggcgccc ggcgaccgtg gaacagacgc tgatcgccct
     7681 ggctcgctta cagggggagg gcgtctccgg ggaagccgtg gcacgggttg acctcgcagc
     7741 gcagcatccc ggctcgaacg caggggtccc cggccatgat ctccgcggcc tcttcggccg
     7801 gcacggtcat gatcgcgacg ccggccacgg tgtcggaggc gaccgggcac aggatcgcga
     7861 tcaccccctc ggcgcgcagc gacaccatgc gccgctggtg ttcgagttcg atcgcgtcgg
     7921 cgccgtccat ggtccgctcc ggcccccact gaaggagcgc caggctgtag ggcttcgcgg
     7981 tcgcggccag agcccggatc tgttcgtcgg tcacggtcgt gctcatgatg tctccttact
     8041 tctcgatgcg ctcggccagc gagacgatga ttccttcggg cccgcggacg taggccatcc
     8101 gccacacgcc ttcgtattcg ccgatgcccc ccaccaggcc gtagccgccg gccgcggcgt
     8161 ggtggaccgc ggcttggagg tcgtgcacct cgaaggcgac gttgcgcagg cccagctcgt
     8221 tggccggcgc ggcaggcgaa cccgggaggt ggtccggccg cgtgaagctc gagagctcca
     8281 gcgtcgtacc tccgccgggt gcccgcagca tgacgatctc ggtgcgggcg ccggtcatgc
     8341 cgatcaccgt gtccaggaac tcgccttcga cggccatctt ctgatcagct tccagaccga
     8401 ggctgacgaa gaacgccgtc gcggcgtcga ggtcggcgac ggtgatgccg acgtggtcga
     8461 agcgcctcac gaatgtcatc ggatcccttt cgaggtttct tcaagagacg ctgagaaagg
     8521 taacacccga ggtttcgtaa gggaacccca cttgctagat tgctgccatg cagcgaacgc
     8581 ggttcgggga gatggcgtgt tccatcgcgc gcaccttgga cgtgatcggc gagccctggt
     8641 cgccgctgat cctgcgcgac gtgtgggccg gggtgcgccg cttcgatcac atccaggccg
     8701 acctggggat ctcccgcaag gtactcaccg agcggctcaa ccatctggtc gaacagggtg
     8761 tgctcgaacg gctgccctac gacgcccgtc cccgctacga gtaccacctc accgccaagg
     8821 gcgtggatct cgtcgagatg ctcatggcga tggcccggtg gggtgaccgc tggctcgccg
     8881 gcgaggccgg gccccccgtc ctgtaccgtc accacgcctg cgggcagatc ggccacgtcg
     8941 agccacgctg cagtcactgc ggggagccga tgcacgccga cgacgtcgat ctcctcccag
     9001 gcccgggttc ggccggatga ccgtgacgac ggtccggacc ccgcggttat ccgaggacga
     9061 gcgggagtct cgtggccagc tcgcccagct cggtcctctc cgcgtctgtg ggggctcgcc
     9121 gtccggtgcc gaccagcagc gcgtccctgt ctgagaacga cgagggaaac gcgctccccg
     9181 cgatcttctc cagcatctcg cgggaccggg caagcccttc cgcgggcggc cccgcggcgt
     9241 ccgccaggtg cgcgaccagg tcgaggtggt gcagcgtcca ctccatgacg tacgcggaca
     9301 ggtaggcgtc cacggtgagg acctcgccgc gggtcccgac ccggaggtcc gggtcggcga
     9361 gctcagcggc gcggcctgcg gcggagccga cgtcgtcgag gtggaacttg agcagccgtg
     9421 gctcctcgta cgcggcggcc agccggacgg tcagcgcgtc gagcgggtcg tcgccggtcg
     9481 gcggcgtcgt ggcgacctcc cagtaggtca ccgcgtcgcg ggtcggttcc gtttccgcgg
     9541 gggtcgccag ggtgatcagg acgtcctgcg cgtcgatgac cagatggcac accagatccc
     9601 gcacgagcca gccggtacag cccgaccgct gggcgaaggc ctcatccgga agctgggcga
     9661 ccgccctgcg caacgccgtc cacgaacgcg cgaaaagatc cacatcggta cggtacttcg
     9721 gcgccacgag gacatccacc tcgccttcct cagcatcggg tgcgccctga tctgctggcg
     9781 ccgcctcagt ttgccacgcc agtagcgagc ccaggctgag cgctgtgagc gtgagcgagc
     9841 ccaccctgga gaccgtacgg gcctatctgc tcgcccaggc gaactccgct ctgcggcgac
     9901 cgagcatgca cggcggagag atcgccgtcc gcctctacct ggacgcggtc gccgtcgcct
     9961 gcggtaccga ccggggcggg caggagagga gacggggcgg tcagttctcc gggtcaggga
    10021 gcaggacgga ggggagggag gtgtcggggt gcaggcgtag tagttggtag agcatgccgc
    10081 ccactcccgg catcagacct gggctgaagg cgtcacgtga aaggccactc accgggccgt
    10141 gctcgtccat gctgccgatc acgtacgcgg cgaggtactc cggcgtcagc tcttcgggcc
    10201 cgacacccac atcgatcgcg tggcgcacga tttcccaggt gccgaggtct ccgtggcaga
    10261 gcgtgtggtt ccagccgatg cccctcgacc aggacgacgc ggcggcccgg cgcagcacgt
    10321 ccgcccagcg cggggcacct tcgcgggcca gccggtcggc cgcgacgagg ccgatgccgg
    10381 cggctccgtg gcaccatgcg ctggaggtca cgcgatggtc gtccatttca cgcaggtcac
    10441 gccagccctt ctccgccggg tcgtacagtg actcctcgta cagaaaggcc ctgtctgcca
    10501 gtgcgcggaa gtccgcagcg ccggccgtgg cactgtcagc gagccgggcc agcgcccagg
    10561 cgatcccggt ggcgccgtgt gagaccccgc ctaacccttg tgggaaggcg gtgctgggcc
    10621 agcgtgctcc ccggtcgtcg atgtgggcca gtgagagcag gcgctccccg atgcggtcgg
    10681 cctgcacgga ccactgctgg tcaccggtct gttccgacag gcggagcaac ggcacgatgg
    10741 cgcctgccat gccggtgagc aggtcgtaca ccccgtcggc ggccaccgcc tcgggcagtt
    10801 gccccgccag ggcgccggcc tgggcgaccg cctcctccga gccgacggtg cccagcctgc
    10861 gcagcagcag ccagctccag atttgcgagc cgatgccgac atagccgcct ggggtggcgg
    10921 ggcggcgccg cggtccggtg cggcgtgcct ccgcgtcgcg ctcctcggcc agcctgatcg
    10981 tatggaggag atcggcgagc agcccgtcca gccccggcac ctcatcggcc ctgccctgcc
    11041 cggtctcact cacgtaggcg gccagagtga tggcgacccc gtacgccccg ccgtacacgt
    11101 cgggagacag cgactgtacg aaccagccgt cggaggtgag caccggcgcg gtccaggtga
    11161 cggtgccgtc gtcgccccgg accgccgtgt caagcatgct gcgggcgatc ccggccgcga
    11221 tccggcgccg gcgccgctcg aggtcctggt gctggatgag aggcacggtc atacgcttgt
    11281 tggcaggcat ccacccttca ttgaggtagg cgctgaccag agcggaccgg atcacctcac
    11341 ggtccagggc cgcgtcgcgg tcgcgccagc gccgcagcgc gtccgcgatg aggtcctgct
    11401 cgtctccgta cgaggttccg ccagggccat ccagacggcc gcgagcaggg gttgtggcga
    11461 agaaggggat gtcgccgacc agcaactcgg ccacctcggc gtcgatcacc tcggggtccg
    11521 atggcgcgcc gggcaggttc tcggcatgct gggccagcaa ccccgccgcc ttgcccatcg
    11581 cggtcggctc gtcgtgcagt gaggccgggt gccacaacat gcgggccagc tcggcgtacg
    11641 cctcggtggc gcggagcacg acccggatcg gacggtcggc gaagtccgtg agcagcccgg
    11701 cgagctcacc ccgccgatcc agcatgtcga ggtgctcggc cagctcggtg aatccggaca
    11761 gcaccagatc ccagtagtgg acgaggatcg gatcggggct cgggtggttg ctcaccgctc
    11821 ccagctcgac ccgttccatt cccaatctcg ccatgtccgt gcccgcgtcg acgacgaccg
    11881 gcacctgcgt gtacggctgc tggccaggca ggcctccgac ggcggacatg tcgacgccgc
    11941 gccaggcgag cgagacgccg cgtccgggaa ggagtccggt gcgcagcacc gatccgctga
    12001 gcaggtcggt cgcctggtcg acggcgtcgc cgtatccgga cggtttggcc gggacgtgcg
    12061 gggtgaacag cgtctcgcag tcgacgacga cgggcgcggg accggccgcg atgaggttct
    12121 ccatgtgcag gtcgctgccg ccgatcagcc gcatcagcgc cagccagtgc ccgacaccgc
    12181 ggtagaagga ccgcagctct gtctcgtcgg cgcagtaggt gtgctggatg tgctccgccc
    12241 agccgtaccc ctggcgaatc agcacgtcgg gtacccggat gcggctgccg gcgggcagct
    12301 ggggtgccag gcggtcgatc agccgcgcca gcgcctcgtc cacggcgagg gaccggggct
    12361 tgtagaccac cttgccctgc gagccgtgca ggacgacgac gctgtgccct ccgcgatggc
    12421 tgtctcccgc cccgaagtcg actccgacca gctcgcctcg gagaccgccg ggcagtgtgg
    12481 tgagcgccgc gcgatcggcg gcgaacctgc gggccagttc cacggccgcg gcgcacctgt
    12541 tgtcgatgat cgtgccgagc ctggacagca tcgtggggta gtgcccggtc agggacagcc
    12601 agaactcggg cgtcgcggcc gtcgccttcc actcctgcca ccgcagctgc ggcgtctcgc
    12661 cggtcagcct tccgctgatc ctggcggcgt tgagttccag cagcagaacc ctgttgacct
    12721 tgaggcggac ggtctcctcc agcgcttcgg cggtgctctg gcagatcagc cgggcctccg
    12781 cttccgtgag gccggggatc gatcccagcg tggcggacag cccggccagc gccggtgcgg
    12841 tcaaaaagtc cagcgacggg tcgaagtccc cggccattcg gatccccctt ccttgatcag
    12901 cagcagaagc ggctgcaggt gcacgagctc gccagccggg tgtccagggc cgtcagcgtg
    12961 atctccgact cggcgtactc gccgatgaac agcggaccgg cggggctgtc ccagccctcg
    13021 acgtcggctc cgctgcgcca cgcggagacg atctcctcag agcgatccag tgtgagaggc
    13081 attgctactc ccttcgtgac tgtgcgttcc gatccgcatt gaccgggtag gtccgatcag
    13141 cagcagggaa tggtgttggc gcccgtgcac gagctcggcc tccgcgtgtc cagggccgtc
    13201 agcgtgatct ccgactcggc gtactcgccg atgaacagcg gaccggcggg gctgtcccag
    13261 ccctcgacgt cggctccgct gcgccacgcg gagacgatct cctcagagcg atccagggtg
    13321 acaggcattc ttactccctc catgaccagg cgtcccgatc agcgttagtc agccgatcga
    13381 aaaaatcaat acatagcggg cgaaatatag actcatcgtc attcggcgga aatggcgaaa
    13441 gctgcggttg gctgtgacgg agcttgcctg gacgccgacg ggatgtccgg aacgcgcgag
    13501 cgagaccggc caccctccac gccacgcgcc cacggcctcc aagggggcga aagcgcaggt
    13561 cagtgggggt tcgtcccgta acgggctatg accaccacct cggcgacggc gctcatgtgc
    13621 gggacgaccc agcgaaccgc tttgatgcgg aagaggcggc cgcgagaagg tttccgctgt
    13681 tcgtagcgcg gcagacggcg gcgaacagcc ccggccacgg ggcgtccggc gacatttccc
    13741 accaatgtgc cggagattct ccacatattg cgggcgacaa ttatcgcgat ttgtgaatat
    13801 agccctccgg cagcgcgccg ccccggcccg agcgcccctc cctccaggcg cagcacgtga
    13861 tccaccacgt gggcgctatg cggccgttca ctcacggtcc ggggccttgg tcgtgaggtc
    13921 gccgtcctct tcgtacggga tccattgcat gccggcgggc atggcgaccg ttccgacgcc
    13981 gctgcggtcc catcccagct gggccacggc gaagatgttg tcggcacgcc ctcgtaatcc
    14041 ggccatggcc gggcacgtcg tcctgttcgg ctcgttgccg gcggcgaccg tcatcacccg
    14101 tacgtctccg gccgccgcca cggccgcctc gcagacatcg caggtgccgt cgcaggcgaa
    14161 cagcccccag cgccgtgagt agcagccgag gctgatgttg acgcacaccg gcgacgacgt
    14221 cctccgcgcg aagtcgcgga cccattcgat ccctttgacg aggtcgcggg gggtcgcgcg
    14281 gccgttgccg tcggcgacct tcacgttgag aaggcgcggc cggcgggtca ggccggccgc
    14341 gaggatgagc gccaccatcg ttccgtggcc gttcgcgtcc tcgccgtcgg gttccgtggt
    14401 caggttggtc ccgtccacga tcagccctcg caggagaggg tgacgggaga gcaggcccgt
    14461 atcgaggacg gcgtaatact caggcgtcgg ttccgggcgc ttcctcgtca gttcgcgcca
    14521 gatttccggc cacgcgcgct ccaacgcgtc cgcgtcgaat tcggctccgg cctgtgcctg
    14581 caggtacgcc gccttcacgc cccgctcgcg gaaggcgagc atctgctcgc tgtccgccgg
    14641 acggaggtac gtgccggtgc cggcgtcgaa aacgtactgc atatatctgc cgggtgagct
    14701 gccctcgtct ccggcgatct cgacaattcg ctcatccata tgagccgtga cccacgacat
    14761 cgccggccta gacgagaagg gaaacgatca gaaggaccac gccggccgcc accagaaggg
    14821 cgcagagtct gaccccgaac tcggagaacc actcggtgaa gcctctccgg ccaccgtctc
    14881 ccagcacgtt cacctgcgcc ggcagtttga cggccacgat ccccgccagc agtgcgccca
    14941 ccaccagcac cgcgagtccg acgctcgtgg tctccgcctt cgccccggcg acctcgccct
    15001 tgaactcgac gacgccgccc aggcccagta tcgccaccac ggcccccgcc acggcgagca
    15061 gaagtcccgt gatgataagc accgtgtacg tgatcgaaat tctggttctg ttggttttct
    15121 tgcccgcacg ccctttgccc atgctgccgc tccagagccc agatcaatac agaaccaacg
    15181 cgaaaggatc tatatcacat cttcttctga agtatccacg gtttcctcga ataaggtttc
    15241 cgatggtcct tctgccggga ctccgagaat gggtgataaa gacagcctta ggcgatattt
    15301 ccgcttgtga gaattacgag aatcgttcga tggtcacggg gatcgggccc gcgtgacgta
    15361 tcgccgtggt caggttccgg agcagcggcc ggagggcgtc gtcggacgtg gtgcccaggc
    15421 gtgccgtgag atcgacgcag caggcgacgc cgggcccgat ccggcgcagt tcccaggtga
    15481 actcgtcccg cgccgtccgc agcccgcccg tgccggcgat ccgggtacgc gggtcatcgg
    15541 cgtccccggc gagcgtgacg acctccggcg cgaggcgggc gaggccggaa aggcggaggt
    15601 cgcccgcgaa caggacgcgg tatgtccggg agtcgtggaa cccgccggag ccctcctccg
    15661 ggccgaggcg caggggagcg gagtccggaa gggcgagggt gtcgcggaag cggtcccgca
    15721 gtgtcgcctc gccggggagt tcccctcctc cgaggcggcg ataggcggcc tcggcgtccg
    15781 tacggccgac ggcgaccacc cggacgcgca gttccgggtc ctcgcgcatg gcccgcccga
    15841 aggccgccga actccaccag gcgcggtcgt ccccgctcca tccggcggtg ttcaggccga
    15901 tggtccgatg gtcgccggtg aagacgaact cctcgacgac gagaccctcc gcccgtacgg
    15961 cgccggcccc cgcctcgggc gcgatcacgt agtagtccag ggccggctgg gtgggggcgg
    16021 aggcggtcgc cgcaagcccg gcccggagga ggtcaccagt cacgggcata ccgtactgat
    16081 ccgccccaca tctgaagcgg tgtctccatc gacgaggcgc ccccgtccct ccgacggggg
    16141 agggctcggg ggcgccgtcg cgtcgcgtcc gtaccgcctg ccgtcgcgac gtacgtgctc
    16201 gcttcaggcc gggtgtgcgg tcgggcgtgt ggtcgggcgt gtggtcgggc gggggccggt
    16261 acgcctcagt gagacatgtc catgccgccg ccggaaccgc cgcccatgtc atggccgccc
    16321 ggcacgttcc ccttctcatc ggacaccatg aagaccccgg ccatgcccat gtcggagtgg
    16381 ctctgcacgt ggcagtggta catccacatg ccgggaccga cacgctctcc cgcgaccacc
    16441 tggaagccga acgactcggc cgggccggtg gtcttcgtgt cgatgatccg gctcgggtcc
    16501 tgggggctct ccagcaggcc ggtgcggttg tcggcccacc ggtgcccgtg gatgtggaac
    16561 gtgtggaacg cgctcccgtg cgtgatcacg atgaactcga cccgctcgcc gatcttggcg
    16621 aggaagtgcg gcccggccgg gaggttgttg atccgcacgt cgttgaagac gacggtgaac
    16681 gtcttgtccg gcagcacgtc gcccttacgg cggaccacca gcgggccgta gaggcccttc
    16741 ttgatgcctc ccgtgccgtg gtcggtgccg accacgtggt cgtggtagtg ccagtagccc
    16801 gcgctgccgg gctcgatggt cccgccgggg cggcggcccg gtgcgtgggt gcgccagacg
    16861 tagacgcgcc gggcccccgg ctcgaccacg ctgtcgttca tccgcgtgcc gtcgctgctc
    16921 gtctcgtagt ccaccccgtg cacgtggagg ctggcggtga cgtccgcgtt gttcaccagc
    16981 tcgacttcga gggtctcgcc ctcgaccatc tcgatgagcg gtccggggat cgtggccttg
    17041 cccggctcga ggccgtagcc catgtcgccg ttcggcaggt tttcgacgta gagggtgatg
    17101 cggcgcgggt tgcccaggcg aacaggcgct gtcgcgttcc tgccgacggg cgccgcgtcg
    17161 gcctgagccg acacgaccag cggtgctatc gcggcggccg tcgccgccgt ggtgaaggcg
    17221 cgccgcgaga acgtgctccg cgtcgttccc ctgcctacct cggtcatggt tccccaatcc
    17281 gttgtgccgt tccgtccgcg aggcgcgtgg ccacgggccg gcggcggggc cgggcctcgc
    17341 ggcgtgacgc cggggccgga ccacgggcgc ggtccggccc tggaaccagg cgggacgaga
    17401 cgggtgcccg atgctttcca ccacaccggg cgacactttt gatggaatta ggcgatagtg
    17461 gccgaggaaa gtcaataagt tagacttaaa gcgataggac ttcgtcacat accggactga
    17521 agtgatgtga gagggctccg ttccgtcgtc gcgccgtcgc attctgtcgt ccacgccgcc
    17581 ggttcgacgg cgattcgcga gccggacggg agtgcgtggc gggtgaccgc gcagggcatg
    17641 ccgggcggcg tgccgggcgt gcaggtgtgc agggtgcgcc gggggcggct cagtcggtgc
    17701 ggaaggggtc gtgctcggcc agcagcttgt cgagcctggc ctggtccacc cggctgacga
    17761 cggtcgcctc ctcctgccgg tcccgcacac acttggccag cgtgaaggtc gaggtcacca
    17821 cgtacatcag cccgagagcg aggaacgagc gcacccaggt cgtgacgggc aggtagagga
    17881 tcccggcggc cagtccggcg agggagatcg cgaacgagat gacggcctgc aggtagaagg
    17941 ccgtcgtcgt cgtgctcttc actggtttcg tcatggcgcc catgctgcgc gcccggcgcc
    18001 gcctggacat gagcgccgat actcagttac cggtgagtac gatctctcgg ccgggccgcc
    18061 gcggcacggc ccggagcggc cacgcgggaa cggctcggcg caggcggcgg ccccaatggc
    18121 acaggctcag tggagtgggc tgggcgaccc ggctcagttc ggggagatct cgtggagccg
    18181 gcagacctga cgccagacgc gggggtcgag ggtgcccgct ctgtcgtcga acgaggcgga
    18241 ggggacccgg accggtccgg tgaggtcgag gaagctgttg tggtccgcgc tcgggtccca
    18301 cgtgcgggtg gggatctcga cgtggtcgga gcggtcgctc cggtcctggc tggtgatctt
    18361 caggacctcc gcgccgccgt ggtacgtcct gagcactacg cagggacgca ccttgtgccc
    18421 gggcccgtcc tcgtacggca cgtcggccca ccagatctcg cccggctgcg ggccggtgcg
    18481 ctcgccggcg gcgcccgtcc gggtttcgcc tcgggtcgta cgggaggagg gcggggagga
    18541 gggccgggcg ccccgtgacg ggcgcgtcgt tgcgccaggg gagcgtggcg cgggccggcg
    18601 gcgggacgtc ccgcgggcgg gcccgcggga cgcctgacgg gcacgtccgg tcccggccag
    18661 cgcggcgagc acgatcagta cggccacgat cagaagagcc acccagagca tgcccgacag
    18721 cctacggccc gtgcgcctcg cggcggcagc cctgcgcccc tgcgcccggt gccgccgggg
    18781 tcgtccatcg tgccccggcc tgtgcgcctc acgggcagcc ctgcgtccct gcgcccggtg
    18841 ccgccgtgat ccatcgtgct ccggccggcg gcttcccggc ggccctgggc tcttgcgccc
    18901 ggtgccgccg gggtcgtcca tcgtgctccg gcccacggct accgggggcc ggacccggct
    18961 cctgctggga acgcgtcagc gggcgtccca ggcagcgagc acgcggcgct ccttgtcggg
    19021 gtcgatgccg ctgcccaccc ggacgccgcg gaagctgcgc cgctcctccg ggatgtcctt
    19081 cagccactcc catgtgtcgc gtaccgtctc gcggagcggg cggcaggtga gaccggcggc
    19141 gagggccttg gcggaggagt ggttccatac acccaggccg tccgcccccg gataccacag
    19201 cggaagctcg gtccacggct ccacgccctg agcggtcagg aagtcgtcgt cggcccagac
    19261 gagctccgcg cccgagccgg tggcctccac gcagtcgccg agccagcttc cgaacgtggc
    19321 cctgcccggc acaccgcccg tcatgtagcg gcccgtcgtg ccaccggcgg cctggtcgag
    19381 ggtgaacgcc gcgatgtcgc gggcgtcgat gagctggatc ggctgcgccg ggttgccggg
    19441 cgcgagcacc cggccgccct tggagatgcg gtcgagccac cagggcagcc ggccgacgtt
    19501 ctcgtgcgga ccgaggatca ggccgggctg gacgaccagg gcggcgccgt cgaagtgctc
    19561 ctccaccgcg cgttcgcagc cggccttgag cacgccgtag tcgccgaact cggcgtccgc
    19621 gtccgccggg cactcgtggg tgggaaaggt ctcgtcgacg cccgtcttgt cgggccagtc
    19681 cgggtaggcg gagatgctgg agatgaacgt gtagtgcgag gcgtgcccgg acagcgcccg
    19741 caccgactcc aggacgaccc gggggacgaa tccgcagacg tcgacgaccg cgtcccaccg
    19801 tctgccgtcg gtgagccgcc gcaggtcgcc ggtcacctcg cggtcgccgc gcaccgcctc
    19861 cactccgggc aggtcagtcc cgctcctgcc ccggttgaac gtcgtgacct cgtgaccgcg
    19921 ccgcagcgcc tcctccacga tggcccggcc caggaagacc gaaccaccga tgaccagaat
    19981 tttcatacgg tcatccttgg cgctgcggcg cgcggagtcc gcccggtttc acgatcggcg
    20041 gacatcgtcc gctcacagcg gaagcgggca ccggtgcgtt cccggccgct ccgttcccgg
    20101 ccactgcgct gagggccggt gcgctgtggg ccggtgcggc tcagccggtg gtgcgcagct
    20161 ccgggaccgg ggtgaagcgt tcctgctcca gcacgtgcac ccgggccgcg ccgatgtcga
    20221 agtagaggcc cgtgagctcc agcctgcccg cccgtacgag cgtgtccaca aaagggtggg
    20281 tccgcaggtt gtcgagctgc tggatgacgt tgacccggca cagccggtcg agcggcccgg
    20341 cgtcgtcggc gtcctggccg ggcccggcgg ccacgaaccg ggccaggctc tgccgtccgt
    20401 gccgcagcca ggcgcgcaac gccggcaggt cggggacctc gccgaggagg gcggccatcg
    20461 cgccgcaccc ggagtgcccg cagacggtga tcatgcggac ctccagcacg ttcacggcgt
    20521 actcgaccgc cgccgccacc gagtcgtccg gcgggaccgc gcccgcccgc ggcacgaggt
    20581 tgccgatgtt ccgcaccgtg aacaggtcac cggggccgct cgcggtgatg atgttgggca
    20641 cgatccgcga gtcggcgcag gtgatgaaca ggtgcgacgg cgactgcccg cgggccatcc
    20701 gggtgagcag gggacggacc atcggcgcgg tcctgcggtg gaactcccgc gtcccctcca
    20761 ggaggtcggg cacgccctgc ggctcgcaga tcacggcgtc gtcgtggccc gcggcgctgt
    20821 cgccatccgc gccgatcacc tcgaaggacc cgtacgggcc cggacccgcg gagtgggcgc
    20881 cggcggagtg ggcgcggcgc cggtaggccc agggcagcca ccagcggtcg tgccggggcg
    20941 ggatcctggc ggggaagagc cgggcgccgc tgatcgcggc ggcgtaccac tcgccgtgcg
    21001 gctcgtccac gtcgacctcg ccgccggcgc gttcgtgctc cagccgccag gtgtgcagcg
    21061 cctcgaaggc ggcgttgtcc atgaagtcga ggtgcaggtc gagctccacc gccgacccgg
    21121 cggggatggc gcgcagcgcc tcggtcagcc ggggcacgcc caggaacgtc agcgatccgg
    21181 tgacgacgac ccgccagtgc cgctcgccgt cctggcggac gtcgaccgag acccatgcga
    21241 ggcggcggag ggcgagcagg gcggccagcc cgaggccgat cgccacgccc tcggcgagcc
    21301 cgatcagcac gaccccggcc atcgtcacgg cgtacaccgg cacctcgcgg tggttgcgca
    21361 ggttccgtac gtgcccgagg ttgaccatct gcacgccgat gaacagcagc agcgccgcga
    21421 gcgcctccag ggggatcagc gcgagcatcc aggcgaaggc cgcggtgaac agcagcaccc
    21481 agacaccgtg caggaccgtg gaccagcggc tgcgggcgcc cgcccgcgcg ttggtggtcg
    21541 tacggacgac gacccccgcc accggcaggc cgccgagcac accggacacc acgttcgcca
    21601 cgccctgcgc ggtgagctcg cggtcgaggt cggcgcgggg gccgtcgtgc aggcggttgg
    21661 acgccacaca ggtcagcagc gactccaccc ccgcgaggag ggcgacgagc aggacggccc
    21721 cggcgatcgc gtgccagtcg ccctggggcg ccagcggccc ctggacggag gagaacccgc
    21781 ccctgaggtc caccttcgtc aggtcccagc ccgacacccc cgccgtcagc gtcgcgatca
    21841 tcagcgcggc cagcggggcg ggcacggccc gcaggcgcgg gatccggccc cacacgagca
    21901 ggaccgtgat cgtcaggacg ccgatcagca cggcgtgcgt gtggttgtgg acgatctggg
    21961 cgggcagttc gagcacgttc tccagcgcgg agcgctgcgg gctgccgccg aggacgatgt
    22021 gcagctggga gagcgcgatc accgcgccga ccccggccag catgccgtgg acgacggcgg
    22081 gggagacccc cagcgccgcc cgcgccaccc gcagcgcgcc gagcccgacc tggaggagcc
    22141 cggccatggc cgtgatcgcg cacgtcgcgc gccagccgta cgtgtggacc agctccgcga
    22201 cgaccaggga gagcccggcg gccgggccgc tcacctggac gacggacccg ccgagcgctc
    22261 ccgcgaccac cccgccgacc accgccgcga cgaggcccgc cgcgacgggg gcgccggacg
    22321 cgacggcgat gccgagcgac agcggcacgg ccaccaggaa gacgaccagc gaggcgggca
    22381 cgtcatggcg gagcacggac ttccagtcac gatgtgaaat cgtgccgtca ctgatggtca
    22441 tgggccgacg atacgtcagc cacggagacc gtcaccaggc agggaacggg aaagtcaccg
    22501 atagtagtcg ggatagtcgg tgtcgggatc gcggtggctg ccccggcgac ggccgccggt
    22561 cgacgtggag gcgtcgccgt acagctcgtc gtaggagggc cagcttccgc ccatgttctg
    22621 ctcgggccac gacggctgcg tgccgccgta cccctgctgt tgctggtcgt agccgtactg
    22681 gctctgtccc gacggcgcgt cgtagcccgc cgactcgtac ggcgaggcgg acccgggcgt
    22741 ggtgcccgtc acgctgtcgg aggcgtcgat cgacgcccag cccgggttca cctcgtacga
    22801 cggcgtgacc ggcggcggta cggacgacga ggagtggtcc gcctggtagc cgtcgtaggc
    22861 cggggtctgg taggtct
//
