LOCUS       NZ_VANP01000001        21110 bp    DNA     linear   CON 22-APR-2024
DEFINITION  Microbispora fusca strain NEAU-HEGS1-5 Scaffold1, whole genome
            shotgun sequence.
ACCESSION   NZ_VANP01000001
VERSION     NZ_VANP01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora fusca
  ORGANISM  Microbispora fusca
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 1094452)
  AUTHORS   Yu,B.
  TITLE     Isolation, diversity and antifungal activity of Actinobacteria from
            wheat
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1094452)
  AUTHORS   Yu,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAY-2019) Northeast Agricultural University, School of
            Life Science, Mucai59, Harbin, Heilongjiang 150030, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005864065.1-RS_2024_04_22
            Annotation Date                   :: 04/22/2024 04:18:05
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,053
            Genes (coding)                    :: 6,990
            CDSs (with protein)               :: 6,990
            Genes (RNA)                       :: 71
            rRNAs                             :: 4, 3, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3, 4 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 11 of 63
            Pseudo Genes (incomplete)         :: 57 of 63
            Pseudo Genes (internal stop)      :: 6 of 63
            Pseudo Genes (multiple problems)  :: 11 of 63
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:39:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 200304
            Orig. end                         :: 221414
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VANP01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21110
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21110
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21110
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11110](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11110
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    267..282
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.55"
                     /tool="antismash"
     misc_feature    269..283
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 20.35"
                     /tool="antismash"
     gene            326..679
                     /locus_tag="FED44_RS00965"
                     /old_locus_tag="FED44_00965"
     CDS             326..679
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541685.1"
                     /locus_tag="FED44_RS00965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_00965"
                     /product="hypothetical protein"
                     /protein_id="WP_111700609.1"
                     /transl_table=11
                     /translation="MRFVHAVTTGALVLAGLTGTSAAALAGTGPTDPSGSAFTGYQVVA
                     LPNANVPNFTRRTVYCPAGKRVVGGGGEAQGNDAVLVGSFPTADGTGWIALGRQPRYDS
                     VGISVYAICAYTS"
     misc_feature    363..383
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.04"
                     /tool="antismash"
     gene            complement(866..1330)
                     /locus_tag="FED44_RS00970"
                     /old_locus_tag="FED44_00970"
     CDS             complement(866..1330)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS00970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_00970"
                     /product="hypothetical protein"
                     /protein_id="WP_138459443.1"
                     /transl_table=11
                     /translation="MRCRWYGRPVLRSGPGLLACASLVLTLAVAAPAAAAAGHPRESHR
                     DRGASAGRDEARPALSASSPISNRGTQQVSVNVANEGIGIQNALCRGSRACDIAQVLAA
                     PSGEDPPAGHPAPRALSRPKTMARRAAHALTHTLTHTAAHAGRRMSHASR"
     gene            complement(1512..1901)
                     /locus_tag="FED44_RS00975"
                     /old_locus_tag="FED44_00975"
     CDS             complement(1512..1901)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS00975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_00975"
                     /product="hypothetical protein"
                     /protein_id="WP_138459444.1"
                     /transl_table=11
                     /translation="MIPALAAGRLTLAVLVAALASAATAREASASTAPLRPGVVTHAAG
                     HGRGHGGGEGQVAAGGVATARQFGSGNGRFNQNLNGVYSPTFMMGQQQTGITVGGRINT
                     QGAFCGPGPKRCKIWQNMPVNAFGW"
     gene            complement(2113..3075)
                     /locus_tag="FED44_RS00980"
                     /old_locus_tag="FED44_00980"
     CDS             complement(2113..3075)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019144.4"
                     /locus_tag="FED44_RS00980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_00980"
                     /product="Sua5/YciO/YrdC/YwlC family protein"
                     /protein_id="WP_138459445.1"
                     /transl_table=11
                     /translation="MGILTSPGGRAAGASATAGTLPVGIDGYGLEHRICPGCVRDLFDP
                     RGRRHLYPLVRCRECGPPAGEPRVRPLALCEDCRRECDRPGSRRGPDDAAGCAACGPAL
                     RWDGLLGRDALAEAVAVIEAGGVVALRDGFADQIVCDAGAEPALARMDGAPGPVRVLVR
                     HVSAARELANLSFLDIRALAERSQPATLVRLREPRLPRAVRRATPDVDLFLPRTPLQHL
                     LTSRFEGPLAVWDRCGERELPYDGTLTVGLDLGLDLSVDLSVGLSVGHGLDQGTGLPAR
                     PAATALPTSSPAWPVWTSPRQDGRPDPSPAPVSPVAQVS"
     gene            3209..4009
                     /locus_tag="FED44_RS00985"
                     /old_locus_tag="FED44_00985"
     CDS             3209..4009
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017583642.1"
                     /locus_tag="FED44_RS00985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_00985"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_244301650.1"
                     /transl_table=11
                     /translation="MTDGPGSPAIDSSASHSARVWNYLLGGKDNYAVDREAGDMIMRMF
                     PDIARIARQQRRFLVRAVRYLTAEAGVRQFLDIGTGLPTADNTHQVAQRVAPESRIVYV
                     DNDPLVLVHARVLLTSTPEGRTDYIEADVRDTDTILAAARNMLDFDRPVALMMLGILGQ
                     LRDEEDPWAVLTRLLDALPPGSYLAVSDGTDTSEALVRAIEIYNANSASSYHLRAPEAL
                     ARFFEGLELVDPGVVTIPRWRPDVADAESSPRAVDAICGVGRKP"
     misc_feature    4028..4046
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.12"
                     /tool="antismash"
     gene            4256..6088
                     /locus_tag="FED44_RS00990"
                     /old_locus_tag="FED44_00990"
     CDS             4256..6088
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013504.4"
                     /locus_tag="FED44_RS00990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_00990"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_138459447.1"
                     /transl_table=11
                     /translation="MTFGGNRFLRGLLTAVTATALGGAGLVLGPTSADAAVGCKVTYAT
                     TQWGTSSGGFTAGVTLTSTGESLNGWKLTFSFPGSQRLTQGWSAWWTQSANHVVAESET
                     WNGSVPSGGSVHLGFNGTWTGSNPPPTDFAVNGVPCQVILIPSPSPSPSPSPSPSPSPS
                     PSPSPSPSPSPSPSPSPSVSPSPDVPVDNPFIGVTGYADPDWAADVESSAAKVDDATAG
                     RMRGLKRTSTAVWLDRIADVTGGPGVTRTLKDHLDEAVRQNAGYVTLVLHDLPDRDCRS
                     LVSNAELHEAQGGLNRYRTEYVDAIAALLARPEYRNLRVATVVEPKALIDLIVGTGTLR
                     CVQAQQSGVYTAGIRYALDRFAPLPNVYTYLDAGNASLAGWDTNFTQLATLITETVRGT
                     AAGTNSLDGIATNVADYVPLTEPFLPDPNRTVAGQQIIMSRFYDWNPHFDERDYALAMR
                     AALVAKGLPSSLGVVIDTSRDGWGGPGRPTAVSTSLDLNTYVDQSRVDRRPSRGAICNQ
                     NGAGLGTRPVAAPVPGVDAYLWIKRPGESDGAGGPIPPAGSDQPLDGVCDPKGNLTPWS
                     DTIRPTNALPNAPLYGDWHHEQFVMLVNNAYPAL"
     gene            complement(6123..8624)
                     /locus_tag="FED44_RS00995"
                     /old_locus_tag="FED44_00995"
     CDS             complement(6123..8624)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040347.3"
                     /locus_tag="FED44_RS00995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_00995"
                     /product="DUF6185 family protein"
                     /protein_id="WP_244301714.1"
                     /transl_table=11
                     /translation="MTTVVGMIPVAMVLRVAVLTSALLAVVALGPRPALAAASECEFGP
                     PGSAWVETSVTVEERGHDTAVMRSTTRVGVPRDWPGAAALFAADGADGCLLLAGGSSTS
                     TATMTPDGAEVVVQRTQETPLQSYDMEWETEVAGLWSSRTSGQTRFVALRLSPAGLPPG
                     LARARWRAVAVRAPDSEVRAVMPLPSEVRPGHTYVWRDAAAPPRVEVALRMSARSAFQR
                     WTGSGGQQVLTVATCLGFALPYLLLAGLLVLLGRRSADRDERALVRIVLGTLAMITAVE
                     VIAAVLLLSGTLFLAHLIGLTDAGAVLILAAPLGAAAWRRARPRSRRAGRAPTGAGRTR
                     SGPTGPAFAGVVLAGAALVAVSGFAPLARRYVHEQAAPAWIASAVATASLLTGAAWVIA
                     VRAARVPDRRTPRAVRALLRWSVPGLALTTLAFVAHAAVTGLRTWGYLPDVVVSPFFLL
                     RNLAYLMWPLVVLLLLLLLRLHGRRTEAVGPLTAWLVAFLFVVGTIRWPSTYAGVPVPL
                     AALAGLTVLSLLLRLTRRAEPADPGVSRRRLAVIVEEHRALEAREKGLRRRWAAGDMDD
                     AAYHRENEPVVERIGRLRGEIGLDPRREDGLTPLDLALARGPGSSWWANARLASRYATY
                     VGAPAAVFLIWATWSTDSMGHDGWLDRLREPNGFYGLAGDLIGGLLIWPVAGFVLGALW
                     RRLPGRRGYLKGAVPVLAYGAATGAHAVLNNLIGQAPVRGSLVRILLLFLVLTVVAVLM
                     DARTLQTRPGGLASRLTPVAVVYRLGTAGSGIALIVAQAAAILGLWTQLRHGIDITSQV
                     DTSTQAPPSTDAQLFQSRPGG"
     misc_feature    complement(6846..6848)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8791..9807)
                     /locus_tag="FED44_RS01000"
                     /old_locus_tag="FED44_01000"
     CDS             complement(8791..9807)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013618.4"
                     /locus_tag="FED44_RS01000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01000"
                     /product="lytic murein transglycosylase"
                     /protein_id="WP_138459449.1"
                     /transl_table=11
                     /translation="MNDQRARTSPVLSLSASRRPRLLAGLLAGGLAGLVSLSGCAGARG
                     EGSPAVSGGAEAPAASVTPPEPPSGGPSAPATPEQPPPAKPPAPDAKIPKDPAALAEAL
                     TRTTALLRDAVDDWRRTGDPARGQAPEPVVLLALYEQRLYRHLARNPGVASRTYGKLSK
                     DQAARARDNVTAVRELLSLAHPVSGPVKFRIEPPEPADVLLDGFRRAGRQFGIDWQVLA
                     AVMLVETKFGRVRSPSYVGAKGPMQFMPGTWKAYGMGGDIDDTRDALLAAANYLHASGA
                     PGDYRRALYAYNHSQAYVDAVLLHTRQMKRDIRNYYAYYNWQVYVITTKGERRLSGP"
     aSDomain        10001..10282
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_FED44_RS01005_Pantocin_Microcin_RRE.1
                     "
                     /evalue="6.30E-20"
                     /identifier="RREFam017.1"
                     /label="FED44_RS01005"
                     /locus_tag="FED44_RS01005"
                     /protein_end="94"
                     /protein_start="0"
                     /score="62.1"
                     /tool="antismash"
                     /translation="MRLPRVKFEHRPHRYEDGTIRIGGEIYGIAAEIEDPYGWVWTALC
                     LMDGTRSSEDIADRLRLAHPELPDAESVVEQLVATRYVEDAAAVPPAAL"
     gene            10001..11110
                     /locus_tag="FED44_RS01005"
                     /old_locus_tag="FED44_01005"
     CDS             10001..11110
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /locus_tag="FED44_RS01005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01005"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_208758781.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.3e-18,
                     bitscore: 62.1, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 6.8e-48, bitscore: 159.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPRVKFEHRPHRYEDGTIRIGGEIYGIAAEIEDPYGWVWTALC
                     LMDGTRSSEDIADRLRLAHPELPDAESVVEQLVATRYVEDAAAVPPAALSEREIDRYSR
                     NQAFFRMVGPGPHSWEAQLRLKGARVVVLGLGGTGSHAAWALAAAGVGEIHCVDPDLVE
                     LSNLNRQVLYGEADVGRPKAEAAVARLRGVNSDITVTGDRRCVGSRRELADLIAGYDAL
                     ALCADRPDGHRIRVWANRACAAAGIPWVGGGYSGPLVTVGCFTPDAGTCYECLCDGEEA
                     RRRPGTPVDLGGPGVIATSAGLSGQLVAHAMIALLTGASAPPAGTIRGVNLIAADHHVR
                     VSHPPRPGCPVCGTRVRARFNSNGRISPA"
     misc_feature    complement(11134..11148)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.75"
                     /tool="antismash"
     gene            11228..11353
                     /locus_tag="FED44_RS37955"
     CDS             11228..11353
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS37955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_259402009.1"
                     /transl_table=11
                     /translation="MTPNEHEIETADEAAPPVKTKITIRLLDKIETTNASNSVGN"
     gene            11478..12119
                     /locus_tag="FED44_RS01010"
                     /old_locus_tag="FED44_01010"
     CDS             11478..12119
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.1"
                     /locus_tag="FED44_RS01010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01010"
                     /product="DUF6879 family protein"
                     /protein_id="WP_138459450.1"
                     /transl_table=11
                     /translation="MASTRTIFDDVRQAEARVLPADAYQAEFAEEFARATGVVWKLERA
                     QEFREPDVPSWRAMMAGDWERSLALIAEMREPLTGYYRTRPATRRLRVVETPLTPYLQW
                     ELRVLAVRAEAGERPRVLAAGAVREFERTAPLPELVAIGSSLLYEVLYDEIGGHVGARR
                     ITDPDLAGPCRAAIETLYQRGEDVRAYVEREVLPLPPPSASSRSRGTYRP"
     gene            12141..13349
                     /locus_tag="FED44_RS01015"
                     /old_locus_tag="FED44_01015"
     CDS             12141..13349
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FED44_RS01015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="FED44_01015"
                     /product="hypothetical protein"
                     /protein_id="WP_138459451.1"
                     /transl_table=11
                     /translation="MSQDAGPPADGTRVRLRDLAFRRDGSQWIVGRPDGQEFAAVPYEG
                     MRAIRLLMEGATIEEAERRLRGETGADLDVRDFVRALGELGFLDEPGRPAAPAEPPTFP
                     RLRARHVRWTLSPLLHTAVAGVIAAGTVTAVIRRETLPGWQDLLWSEHGTLVLLSEIAV
                     GWTLIFLHEMAHLSTARAAGVPGRIRLGTRLQFLAVQTEVSGIWLAERRVRLTVYLAGM
                     AVDAAACSAAVILAAVLGRHTVLSLVTLTSVSMLTTQFLVFMRTDVYFLLQDLTGCRNM
                     YGDATAYARHRVLRLLGRPTPDPLAGLPRRERRSLRAYAVLMVVGTVVCLGVAFAVTLP
                     ATLVLLCRAVRALGTPATPLSVLDAAAVLLAALAFQVAWARAWWRRHGPRLRRTLPRTR
                     TRP"
     misc_feature    complement(13392..13405)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.27"
                     /tool="antismash"
     misc_feature    complement(13398..13407)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     gene            13476..13904
                     /locus_tag="FED44_RS01020"
                     /old_locus_tag="FED44_01020"
     CDS             13476..13904
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890617.1"
                     /locus_tag="FED44_RS01020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01020"
                     /product="hypothetical protein"
                     /protein_id="WP_111700600.1"
                     /transl_table=11
                     /translation="MTHLEKRAWIRLVVAVLAYAAYVVVVLRRADGGPLPDTPYTAALL
                     WSVGGAIAATIAAEIGMAIVNPRASRVQDARDREIGRFGDHVGQAFVVIGAVAAMLMAM
                     AGWDRFWIANVVYLCFVLSAVLAGIAKVVAYRRSLPEW"
     misc_feature    13578..13580
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13898..14131
                     /locus_tag="FED44_RS01025"
                     /old_locus_tag="FED44_01025"
     CDS             13898..14131
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890616.1"
                     /locus_tag="FED44_RS01025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01025"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_138459452.1"
                     /transl_table=11
                     /translation="MVKPTRVTNRIRTLRFTHDEMTQAELAERVGVTRQTLIAIEQGRY
                     SPSLEMAFRIARVFGVPLDDVFQYPDLPEETP"
     gene            14128..15117
                     /locus_tag="FED44_RS01030"
                     /old_locus_tag="FED44_01030"
     CDS             14128..15117
                     /NRPS_PKS="Domain: PKS_ER (12-323). E-value: 1.1e-43.
                     Score: 141.5. Matches aSDomain:
                     nrpspksdomains_FED44_RS01030_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890842.1"
                     /locus_tag="FED44_RS01030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01030"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_138459453.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.7e-18, bitscore:
                     60.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVQDAYGPADVLRLSDVDRPEIGAEEVLIEVRAAAVDPGVWV
                     LMTGRPYLMRLAGFGLRRPKVVVRGRDVAGVVAAVGAGVTRFRPGQEVYGTCTSGSYAE
                     FARARQNRLAPKPAGLTFEQAAAMPVSGMTALQAVRDVAGVRPGQRVLVIGASGGVGSF
                     AVQIARAYGASVTGVCSAAKAGFVRSLGADDVVDYAQEEIDRDGPRYDVVVDTAGNRPL
                     SLLRRALTPRGTLAVVGGGHVAHRFTGGMGRTFRAPLLSPFTGQRLRPVMTRERAEDLE
                     ELTRLAESGAVTPMIDRVYPLADAPDAIRHLMGGHPGGKVVVTVNGTA"
     aSDomain        14164..15096
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FED44_RS01030_PKS_ER.1"
                     /evalue="1.10E-43"
                     /label="FED44_RS01030_PKS_ER.1"
                     /locus_tag="FED44_RS01030"
                     /protein_end="323"
                     /protein_start="12"
                     /score="141.5"
                     /tool="antismash"
                     /translation="DVLRLSDVDRPEIGAEEVLIEVRAAAVDPGVWVLMTGRPYLMRLA
                     GFGLRRPKVVVRGRDVAGVVAAVGAGVTRFRPGQEVYGTCTSGSYAEFARARQNRLAPK
                     PAGLTFEQAAAMPVSGMTALQAVRDVAGVRPGQRVLVIGASGGVGSFAVQIARAYGASV
                     TGVCSAAKAGFVRSLGADDVVDYAQEEIDRDGPRYDVVVDTAGNRPLSLLRRALTPRGT
                     LAVVGGGHVAHRFTGGMGRTFRAPLLSPFTGQRLRPVMTRERAEDLEELTRLAESGAVT
                     PMIDRVYPLADAPDAIRHLMGGHPGGKVVV"
     CDS_motif       14569..14631
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FED44_RS01030_0001"
                     /evalue="9.30E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="FED44_RS01030"
                     /protein_end="168"
                     /protein_start="147"
                     /score="18.2"
                     /tool="antismash"
                     /translation="GQRVLVIGASGGVGSFAVQIA"
     misc_feature    complement(15167..15183)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.92"
                     /tool="antismash"
     gene            15203..16129
                     /locus_tag="FED44_RS01035"
                     /old_locus_tag="FED44_01035"
     CDS             15203..16129
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911705.1"
                     /locus_tag="FED44_RS01035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01035"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_111700597.1"
                     /transl_table=11
                     /translation="MTDLQIAVDMPAPQTHERAARETGGWPMLILALLGLLSPFVLVPV
                     GIGIAADGSGGPGAVLIIAGVLLLLVAVVAFTGLTAVAPGEARVIQLLGRYVGTVRTPG
                     LRFVVPFTQKRRVSTRIRNHETDVSKVNDADGNPIEMAAVVVWQVEDTAKAVFEVDDFV
                     EFVAFQTETAVRHIAGSYPYDGHDDVLSLRQNADEITGRLSAEIQARVASAGVRVIESR
                     ITRLAYAPEIAQAMLRRQQAGAVVAARQRIVEGAVGMVEAALARLDEHDVIELDEERKA
                     TMVSNLLVVLCGDRDVQPVVNTGSLYR"
     gene            16132..16404
                     /locus_tag="FED44_RS01040"
                     /old_locus_tag="FED44_01040"
     CDS             16132..16404
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017580057.1"
                     /locus_tag="FED44_RS01040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01040"
                     /product="hypothetical protein"
                     /protein_id="WP_208758782.1"
                     /transl_table=11
                     /translation="MATDRKSILLRLDPAVHDALARWAGDELRSTNAQIEFLLRQALAD
                     AGRLPREAARIPRRGRPPRTSAPPNGSAASQKPDEPEGGAPPGDD"
     gene            16419..17066
                     /locus_tag="FED44_RS01045"
                     /old_locus_tag="FED44_01045"
     CDS             16419..17066
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657878.1"
                     /locus_tag="FED44_RS01045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01045"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_138459454.1"
                     /transl_table=11
                     /translation="MNVPGSLPARLYLLGYDPRKERVVTNYRFPYLLRAAALTELLLEG
                     RIADERGKVRVVSEQPLGDPVLDDLLHQIAGSRPKPWRHWIDKDGRATVRAVRDELETR
                     HWVRVELRQPFLLVFNRTRVRVRDPRVVKRLTTQVATALNGPMSRVGEREAALVALAAA
                     GELRTVLPRARRKAYKQRIAELGERGGPATPALRKVIQQLHAASAAAMSGGG"
     gene            complement(17122..17703)
                     /locus_tag="FED44_RS01050"
                     /old_locus_tag="FED44_01050"
     CDS             complement(17122..17703)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543422.1"
                     /locus_tag="FED44_RS01050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01050"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_111700594.1"
                     /transl_table=11
                     /translation="MGNREDLLAGARRCLMEKGYSGTTARDIATAAGTSLASIGYHFRS
                     TKALLNAALVDAMEEWGKEIERTLAAGPALGGTPAQRFEATWTRIIESFARLRPLWAIQ
                     FELIAQMDRLPELREAFATANRQAKLGLAALFENLDPAADPRKAMAVGAFYQALLGGMA
                     AQWLVDPDEAPSAADLAEALRTIAPGLAAQ"
     misc_feature    17758..17772
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.83"
                     /tool="antismash"
     gene            17787..18995
                     /locus_tag="FED44_RS01055"
                     /old_locus_tag="FED44_01055"
     CDS             17787..18995
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543421.1"
                     /locus_tag="FED44_RS01055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01055"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_138459455.1"
                     /transl_table=11
                     /translation="MTNILISGGSVAGLTLAYWLREYGFTPTVVERAPRLREGGYKIDI
                     RGAALDVVGRMGLLDEVRGHSTDMRVARFVDARGKQVATMNAEVFGGREGDDVEIMRGD
                     LVRILHGAAGDGVEYVFDDSVTALERTPGGVRVTFESGPPRTFDLVVGADGLHSNVRAL
                     AFGEESRFVRDLGHHISIFTVPNHLGLDRTEMMHPAPGRSAGMYGTRRDADARAMFLFS
                     SPPGAGDGRDVTRQKNLLAEVFADQGWDVPRLLDAMWDAPDFYFDSISQVCMDGWSSGR
                     VALVGDAAYGPSPASGQGTSLALVGAYVLAGSLAAAAADHTAGFAAYEREMRHFVEENQ
                     KLAAPNIKGMVLRSAAQIRFQMLMLRLMPHLPGKDRMIERVTGPIRRAATAITIRDYRV
                     PSV"
     gene            complement(19241..21070)
                     /locus_tag="FED44_RS01060"
                     /old_locus_tag="FED44_01060"
     CDS             complement(19241..21070)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546213.1"
                     /locus_tag="FED44_RS01060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FED44_01060"
                     /product="family 43 glycosylhydrolase"
                     /protein_id="WP_138459456.1"
                     /transl_table=11
                     /translation="MGSAFTLRARLRRGVVWMAGLLCMAALLPATTAKADNPIVQTIYT
                     ADPAPLVYNGRVYLYTGHDEDGSTYFTMKDWRVFSTTDMVNWTDHGSPLSVATFSWAKS
                     DAWAGQAVYRNGKFYWYVPTTNRSTGRMAIGVAVSDSPTGPFKDAIGRPLVENGEIDPT
                     VYIDDNGQAYLYWGNPNLWYVKLNSDMISYSGSATKVTLTTSGFGTRTGDANRPTLFEE
                     GPWFYKRGSLYYMVFAAKCCSEFIAYSTSSSPTGPWTYRGTIMSTQGSSFTNHPGIIDY
                     NGGSYFFYHNGALPGGGGYTRSVAVEKFTYGSDGSIPTINMTTTGAPQIGTLNPYVRQE
                     AETIAWESGVETEASTEGGMNVGFIENGDYIKVKGVAFGSGATSFSARVASANSGGKIE
                     LHLDGVNGTLVGTCNVSGTGGWQTWTTVSCSVNGATGTHDLYLKFTGGSGNLFNVNWWQ
                     FSGNGQPSPSATPSQSPSQSPSQSPSQSPSQSPSQSPSQSPSATPTRTPTPPVTGACSA
                     TYRTTNTWSGGFQGEVTVTAGSEAISGWTVKWTLAGGQTISQVWNGTLTTSGSTVSVSN
                     ASYNGSLAPSASTTFGFLANGTASTPTVTCTGS"
ORIGIN
        1 gaccgcggcg gccgtgccga gcgtcgtcat ggcggcgagc acggagacag cgacgatctt
       61 tctcatgcga tccccccgag gaggaacgta cccacgagcg acaatccgcc ccaggtgccc
      121 cgccggacca caatggacga ccgtgacctc acgtcattgt gagatcggag aagtcgccac
      181 gttgggtaaa cggaatattg cctagtgtgg tcgaagaaga tcgcgggtag atgtggtccc
      241 ggaaccgaag gggacggcct tccgccgttc aaactcattt tcctcggtcc aaatccggtc
      301 attctcgaca caacggagct tttacgtgcg atttgttcac gcagtcacga ctggcgccct
      361 ggttctcgcc ggactgacgg gtacgagcgc ggccgccctg gccggcaccg gaccgaccga
      421 cccctccggg tcggcgttca ccggctacca ggtcgtcgcc ctgcccaacg cgaacgtgcc
      481 gaacttcacc cggcgcaccg tgtactgccc ggccggcaag cgggtcgtgg gcggcggcgg
      541 cgaggcgcag ggcaacgacg ccgtcctcgt gggcagcttc cccacggccg acggcaccgg
      601 ctggatcgcc ctcggccggc agccccgcta cgacagcgtg ggcatcagcg tctacgccat
      661 ctgcgcgtac accagctgac atggcccgcc cgcggcgcgc cacacagcgc gccgcggacg
      721 cggcccgcgc cgaggaaccg gcgcaggccc gactccagga caggccaccg gcggggcgcg
      781 gagccgcacc gcagtgaatc aacccgggcg cgtgacaggc gtcttcccgc atgcgccaga
      841 gcgggcgcgg accgcgccgg gaggctcacc gcgaggcgtg ggacatgcgc cttccggcgt
      901 gcgccgccgt gtgcgtcaga gtgtgcgtca gggcgtgggc ggcccggcgg gccatggtct
      961 tgggacgcga gagcgcccgc ggggcggggt gcccggcggg cgggtcctcc ccggaaggcg
     1021 cggcgagcac ctgggcgatg tcacacgccc ggctcccccg gcacaacgcg ttctggatgc
     1081 cgattccctc gttcgcgacg ttgacggaga cctgctgggt gccccggttg ctgatggggc
     1141 tcgacgccga gagcgccggc cgcgcctcat cccttcccgc cgacgctccc cggtcccggt
     1201 gcgactcccg cggatgaccg gccgcagcgg cggcgggcgc cgcgacggcg agagtcagca
     1261 cgagcgacgc acaggcgaga agccccggac cgctccgcag aaccggcctg ccgtaccacc
     1321 gacacctcat cgcgcgccgc tcccgtcagc cggaccgctc ctgcggcccc tcctcgtgcg
     1381 gggccgttac tcaggctagt gatccgcctt ttcccagcgt ccggcacgcg cggcgtctta
     1441 cgccatcatt gccatattcg tcggcgcacg gtccggtcga tcgattcgcg gccgacgcgc
     1501 ggcgggaaac gtcaccagcc gaaggcgttg accggcatgt tctgccagat cttgcaacgc
     1561 ttcgggccgg ggccgcagaa ggcgccctgg gtgttgatgc ggccgccgac cgtgatgccg
     1621 gtctgctgct ggcccatcat gaaggtcggg ctgtagacgc cgttgagatt ctggttgaac
     1681 ctgccgttcc cggagccgaa ctgcctggcc gtggccaccc ctccggccgc cacctgcccc
     1741 tcaccgcctc cgtgcccacg tccgtgtccg gcggcgtgcg tcaccacgcc cgggcgcagc
     1801 ggagccgtgc tcgcactcgc ctcccgcgcg gtggcggccg aggcgagcgc ggccacgagg
     1861 acggccagtg tcaggcggcc ggccgcgagt gccggaatca ttcgcgaagg ggccgtacag
     1921 tcgcgggaca tctggaaacg cacctactca ccaaggccat ccggcgacgg gtctcgtcgt
     1981 ggacataagc aacgatgccc tcatacccca ttcgatggcc tcggttccgg ccctgccaag
     2041 cgcggcatgg atgatgactc agcttttgcc gcaattccgc ttatccggca aatacgcgca
     2101 gaatcaccat ttctacgaca cctgggcgac cggtgacacg ggagcgggcg acgggtccgg
     2161 cctgccgtcc tgcctcggag acgtccacac gggccacgcc ggcgaagacg tcggcagcgc
     2221 cgtggcggcg ggccgcgccg gaagacccgt cccttgatcg agcccgtgac cgacgctcag
     2281 accgacgctc agatcgacgc tcagatcgag gcccaggtcg aggcccacgg tcagcgttcc
     2341 gtcgtacggc agttcccgct cgccgcatcg gtcccagaca gcgagcgggc cctcgaagcg
     2401 cgacgtgagc agatgctgca gcggagtgcg gggcaggaag aggtcgacgt cgggcgtcgc
     2461 ccggcgcacc gcccggggca gtcgcggctc gcgcagccgg accagtgtgg ccggttggga
     2521 gcgctcggcg agcgcgcgga tgtcgaggaa ggacaggttc gccagctccc gggccgccga
     2581 gacgtgccgc accagcacgc ggaccggacc cggcgcgccg tccatccggg cgagcgcggg
     2641 ctcggccccg gcgtcgcaga cgatctgatc ggcgaaaccg tccctgagcg ccacgactcc
     2701 cccggcctcg atcaccgcga ccgcctccgc cagtgcgtcc cggccgagca gcccgtccca
     2761 gcgcagcgcg gggccgcagg ccgcgcatcc cgcggcgtcg tccgggccgc gccgcgaacc
     2821 gggccggtcg cactcgcgcc ggcagtcctc gcacagggcg agcggccgta cgcgcggctc
     2881 gccggcgggg ggcccgcatt cacggcaacg gaccagcggg tagagatgcc tgcgcccgcg
     2941 cgggtcgaac aggtcgcgta cgcagccggg gcagatgcgg tgctccaggc cgtacccgtc
     3001 gatgcccacc ggcagggttc ccgccgtcgc ggaagcaccg gcggcccgcc cgccgggaga
     3061 agtcaagatg cccatggcgt ccgcactgcc ccggatgatc gacactaatc ccagagacac
     3121 caatagccac agatgtcaca tattgcgcat ctcgacccct ggcgcgagac tgatgatctc
     3181 gatcggcaca gcagaccgga gaaccacggt gaccgacgga ccaggatcgc ccgcgatcga
     3241 ctcctccgcc tcgcactcgg cccgcgtctg gaactacctc ctgggcggca aggacaacta
     3301 cgccgtcgac cgcgaggccg gcgacatgat catgcggatg ttccctgaca tcgcccggat
     3361 cgcccgtcag cagcggcgtt tcctcgtccg cgcggtgcgc tacctgacgg ccgaggcggg
     3421 tgtgcgccag ttcctcgaca tcggcaccgg cctgccgacc gccgacaaca cccaccaggt
     3481 cgcccagcgc gtcgcccccg agagccggat cgtctacgtc gacaacgacc cgctcgtcct
     3541 ggtgcacgcg cgggtgctgc tcaccagcac gccggagggc aggaccgact acatcgaggc
     3601 cgacgtgcgc gacacggaca cgatcctggc cgccgcccgg aacatgctcg acttcgatcg
     3661 gcccgtcgcg ttgatgatgc tcgggatcct ggggcagctt cgcgacgagg aggacccgtg
     3721 ggcggtcctg acccgcctgc tcgacgccct gccgcccggc agctatctgg cggtgagcga
     3781 cggcaccgac accagcgagg cgctcgtgcg ggccatcgag atctacaacg ccaactccgc
     3841 gagttcctac cacctgcgcg cccccgaggc gctcgcccgc ttcttcgagg gcctggagct
     3901 cgtcgacccc ggagtggtca ccatcccccg ctggcggccc gacgtcgcgg acgccgaaag
     3961 ctctccccgc gccgtggacg cgatctgcgg cgtcggccgc aagccctgac ggacggccgg
     4021 ccccggccgc tgaatatttc accggctccg gagtgggccg gcaggggtct cgtacggatt
     4081 ctccgaggtc ccctcacact ctcgtccgtt cgttgcggaa agggcgcttt cccctgacgc
     4141 ggacggtgta cacgcgccgg gcgattgatg agtctgggga tcgtcggcgc ccctccggca
     4201 tccggagcgg ccgccgggac acgcccggct cacctcacct ggagaacgat cgcccatgac
     4261 attcggcggc aaccggtttc tacgcggact cctgacggcc gtcacggcca cggccctggg
     4321 cggagcgggg ctcgtcctgg gcccgacctc cgccgacgcc gccgtcggct gcaaagtgac
     4381 ctacgcgacc acccaatggg gcacgagctc gggcggcttc acggccggcg tcaccctcac
     4441 gagcaccggc gagtcgctga acggctggaa gctgacgttc tcgttcccag gctcccagag
     4501 gctcacgcag ggctggtcgg cctggtggac ccagtccgcc aaccacgtcg tcgcggagag
     4561 cgagacatgg aacggctcgg tgccctccgg cggatccgtc cacctcggct tcaacggcac
     4621 ctggaccgga agcaacccgc cgcccacgga cttcgccgtg aacggggtgc cgtgccaggt
     4681 gatcctcatt ccgagcccgt cgccgagtcc ttccccgagc ccttcgccca gcccctcacc
     4741 gagcccttca cccagccctt caccgagccc ttcacccagc ccttcaccga gtccgagcgt
     4801 cagcccgagc ccggacgttc cggtggacaa cccgttcatc ggcgtcaccg ggtacgccga
     4861 cccggactgg gcggccgacg tggagtcctc cgccgccaag gtggacgacg ccaccgcggg
     4921 caggatgcgc ggcctgaaga ggacgtcgac cgcggtctgg ctcgaccgca tcgccgacgt
     4981 caccgggggc cccggcgtga cgaggacgct caaggaccac ctcgacgagg ccgtgcggca
     5041 gaacgccggc tacgtcacgc tcgtgctgca cgacctgccc gaccgcgact gccggtcgct
     5101 ggtctccaac gccgagctgc acgaggcgca gggcggcctc aaccgctaca ggaccgagta
     5161 cgtcgacgcc atcgccgccc tcctcgccag gcccgagtac cggaacctac gcgtcgcgac
     5221 ggtcgtcgaa ccgaaggcac tgatcgacct catcgtgggc acgggcaccc tgcggtgcgt
     5281 gcaggcgcag cagtcgggcg tgtacacggc gggcatccgg tacgccctcg acaggttcgc
     5341 gccgctgccc aacgtctaca cgtacctgga cgccggcaac gcgtcgctcg caggctggga
     5401 caccaacttc acgcagctgg cgaccctcat caccgagacc gtgcgcggca cggcggcggg
     5461 gacgaacagc ctcgacggca tcgccacgaa cgtcgccgac tacgtccccc tcacagaacc
     5521 gttcctgccc gaccccaacc gcaccgtggc cggccagcag atcatcatga gcaggttcta
     5581 cgactggaac ccgcacttcg acgagcggga ctacgccctc gcgatgcgcg ccgccctcgt
     5641 cgccaagggc ctgccgagct cgctcggcgt ggtgatcgac acctcccgcg acggctgggg
     5701 cggaccgggc aggcccacgg ccgtgagcac ctcgctcgac ctcaacacgt acgtggacca
     5761 gagccgcgtc gaccggcgcc cgtcgcgggg cgccatctgc aaccagaacg gcgcggggct
     5821 gggcacgcgg ccggtcgcgg cgcccgtgcc cggggtcgac gcctacctgt ggatcaagcg
     5881 gcccggcgag tcggacggag cgggcggccc gattccgccc gcgggctcgg accagccgct
     5941 cgacggcgtg tgcgacccca agggcaacct cacgccctgg tcggacacga tacggccgac
     6001 caacgccctt cccaacgcac cgctctacgg cgactggcac cacgagcagt tcgtgatgct
     6061 ggtgaacaac gcctaccccg ccctctgagc acgctccggt gccccccgag acgtccgggc
     6121 ggctatccgc ccggacggct ctggaacaac tgggcgtcgg tgctcggggg cgcctgtgtc
     6181 gaggtgtcga cctgggaggt gatgtcgatg ccgtgcctga gctgggtcca caggcccagg
     6241 atcgccgccg cctgggcgac gatgagcgcg atcccgctgc ccgccgtacc gagccggtag
     6301 acgacggcca cgggggtgag ccgcgacgcg aggccgcccg gacgggtctg gagcgtgcgc
     6361 gcgtccatga ggacggcgac cacggtcagg accaggaaga gcagcaggat ccggacgagg
     6421 gaaccgcgca ccggggcctg tccgatgagg ttgttcagca cggcgtgcgc cccggtggcc
     6481 gcgccgtacg cgagcacggg cacggccccc ttcaggtaac cgcgcctgcc gggcaggcga
     6541 cgccacagcg cgcccagcac gaacccggcg accggccaga tcagcagccc tccgatcagg
     6601 tcgccggcca gcccgtagaa cccgtttggc tcgcggagcc ggtcgagcca gccgtcgtgg
     6661 cccatgctgt cggtgctcca ggtggcccag atgaggaaca cggcggcggg cgcgcccacg
     6721 taggtcgcgt accgcgaggc gagccgcgcg ttggcccacc atgagctccc cgggccgcgc
     6781 gccagcgcga ggtcgagcgg ggtcaggccg tcctctctgc ggggatcgag gccgatctcc
     6841 ccgcgtaacc gcccgatgcg ctccacgacc ggctcgttct ccctgtggta ggcggcgtcg
     6901 tccatgtctc ccgcggccca gcgccggcgc aggcccttct cccgcgcctc cagggcccgg
     6961 tgctcctcga cgatcacggc gagccgccgc cgcgacacgc ccgggtccgc gggctcggcc
     7021 cgtcgcgtca gccgcagcag cagagacagc accgtcagac cggcgagcgc ggcgagcggg
     7081 acgggcaccc ccgcgtacgt gctgggccat ctgatcgtgc ccacgacgaa caggaaggcg
     7141 acgagccacg cggtgagcgg cccgacggct tccgtgcgcc gtccgtgcag acgcagcagc
     7201 agcagaagca ggagcaccac aagcggccac atcagatagg cgaggttccg cagcagaaag
     7261 aagggcgaaa cgacgacatc cggcaggtat ccccaggtcc gcaggccggt gacggccgcg
     7321 tgggccacga acgccagggt cgtcagcgcg agccccggga cgctccatcg cagcagcgcg
     7381 cggacggccc ggggcgtcct cctgtccggt acgcgagccg cccgcaccgc gatcacccac
     7441 gccgctccgg tgagcagcga cgccgtagcg acggccgatg cgatccacgc gggtgccgcc
     7501 tgctcgtgga cgtaccgcct ggccaggggc gcgaagccgc tgacggcgac gagcgccgcc
     7561 cccgcgagca ccactcccgc gaacgccgga ccggtgggcc ctgaacgggt gcgcccggca
     7621 ccggtgggcg cccggccggc ccgccggctt cgcggacgcg cccgccgcca cgcggccgcg
     7681 ccgagcggcg ccgccaggat gagaacggcc cccgcgtcgg tcaggccgat gaggtgggcc
     7741 aggaagagcg tcccgctgag gaggagcacg gccgcgatca cctccaccgc ggtgatcatc
     7801 gccagggtgc cgagaacgat ccttacgagg gcgcgctcgt cccggtcggc cgagcgccgg
     7861 ccgagcagca cgagcagtcc ggcgagcagc aggtacggca gcgcgaagcc caggcaggtc
     7921 gcgaccgtga gcacctgctg tcctccagag ccggtccagc gctggaacgc ggaccgcgcg
     7981 gacatccgga gggcgacctc gacgcgcggt ggcgcggcgg cgtcccgcca cacgtatgtg
     8041 tgaccgggcc gcacctccga cggcaggggc atcactgcgc gcacctcgga gtccggcgcc
     8101 cgcacggcca cggcccgcca tcgcgcccgg gccagcccgg gcggcaaacc ggccggtgag
     8161 agccgcaacg cgacgaaccg ggtctggccg gacgtccggc tcgaccacag cccggcgacc
     8221 tccgtctccc actccatgtc gtacgactgc agaggagtct cctgggtgcg ctggaccacg
     8281 acctcggcgc cgtccggcgt catcgtggcc gtcgacgtcg acgaaccgcc ggccagaagc
     8341 aggcagccgt cggcgccgtc ggcggcgaac agggcggcgg cccccggcca gtcgcggggc
     8401 acgccgaccc gcgtcgtgct cctcatcaca gcggtgtcgt ggccgcgttc ctcgacggtc
     8461 acggacgtct cgacccaggc ggaaccggga ggcccgaact cgcactccga agcggcggcg
     8521 agcgccgggc gcggaccgag agccaccacc gcgaggagcg ccgacgtcag gacggcgact
     8581 ctgagcacca tcgcgacggg gatcattccc acgacggtcg tcatctgccg cacagccgac
     8641 ctccccgcgc gattgggctc caaaggatca gtcgctcggg aggcggcatt ggttacagcc
     8701 agggcggaat gtcggtgcgg tcgccggccg tgccgtcaga ggccgttcag gggccgctca
     8761 ggggccgctc aggggccgct caggggccgc tcaggggccg ctcaggcgcc gttcgccctt
     8821 cgtcgtgatg acgtacacct gccagttgta gtaggcgtag tagttcctga tgtcgcgctt
     8881 catctggcgg gtgtgcagca ggaccgcgtc cacgtacgcc tgggagtggt tgtaggcgta
     8941 cagcgcccgc cggtagtcgc ccggcgctcc cgacgcgtgc aggtagttgg ccgcggcgag
     9001 cagggcgtcc cgggtgtcgt cgatgtcgcc gcccatcccg tacgccttcc aggtgccggg
     9061 catgaactgc atcggcccct tggcgccgac gtaactcggc gaccggacgc ggccgaactt
     9121 ggtctccacg agcatgaccg cggccagcac ctgccagtcg atcccgaact ggcgcccggc
     9181 ccggcggaag ccgtcgagca ggacgtccgc cggttcgggc ggctcgatgc ggaacttgac
     9241 cggcccgctg acggggtggg ccagggagag cagttcgcgt acggccgtca cgttgtcccg
     9301 cgcccgcgcg gcctggtcct tggacagttt cccgtaggtg cgcgacgcga cgccggggtt
     9361 acgggccaga tgacggtaga ggcgctgctc gtacagggcg agcaggacca ccggctcggg
     9421 ggcctgtccc ctggcggggt cccccgtgcg ccgccagtcg tcgacggcgt cccgcagcag
     9481 cgcggtcgtc cgggtcagcg cctcggccag cgcggcggga tccttgggaa tcttcgcgtc
     9541 gggcgcgggc ggcttcgcgg gcggcggctg ctccggcgtc gccggcgcgg acgggcctcc
     9601 ggaaggcggc tccggcggcg tcacggacgc ggccggagcc tcggccccgc cggagacggc
     9661 cggcgatccc tcgccccgcg cgccggcgca gccggacagc gagaccagac cggcgagccc
     9721 gcctgccagc aggccggcga gcaggcgcgg acgccgcgac gcggagaggg acaggacagg
     9781 actggtacgg gcacgctgat cgttcatcgg tcccaacgta tgcccggcgg cgccgtttca
     9841 cgtcgtcccg acgccgggac gccgcgcgcc gccgtccccc ggctggcggc ggcgacggga
     9901 gggatacagt cggccgtaac cttttccggc cgcaccccat tccccgtttt cccacctcag
     9961 gtgttgaccg gataagtaac ctggcagtaa tgctcgactc gtgcgcctgc cccgggtgaa
    10021 attcgagcac cggccccacc ggtacgagga cggcaccatt cgcatcggcg gcgagattta
    10081 cgggatcgcc gccgaaatcg aggatccgta cggctgggtc tggaccgccc tgtgcctgat
    10141 ggacggcacc cgctccagcg aggacatcgc ggaccggctc cgcctggccc atccggagct
    10201 gccggacgcc gagtcggtcg tcgagcagct cgtcgcgacc cgatacgtgg aggacgccgc
    10261 cgccgtgcca cccgccgcgc tgagcgagcg ggagatcgac cggtacagca ggaaccaggc
    10321 gttcttccgg atggtcggcc cgggcccgca cagctgggag gcacagctgc ggctcaaggg
    10381 cgcgcgggtg gtggtgctgg ggctgggcgg cacgggcagc cacgcggcgt gggccctcgc
    10441 cgccgcgggc gtgggcgaga tccactgcgt ggatcccgac ctggtcgagc tgtcgaacct
    10501 caaccgtcag gtgctgtacg gcgaggccga cgtgggacgg ccgaaggccg aggcggccgt
    10561 cgcgcggctg cgcggcgtca actccgacat caccgtcacc ggcgaccggc ggtgcgtcgg
    10621 cagccgccgt gaactcgccg atctgatcgc gggttacgac gcgctcgccc tctgcgccga
    10681 ccggccggac gggcaccgca tcagggtgtg ggccaaccgc gcctgcgccg cggcggggat
    10741 cccgtgggtg ggcggcgggt acagcgggcc gctggtcacc gtgggctgct tcaccccgga
    10801 cgccggcacc tgctacgagt gcctgtgcga cggcgaggag gcccggcgcc gcccgggcac
    10861 gccggtggac ctcggcgggc cgggggtgat cgccacgtcg gcgggcctgt ccggccagct
    10921 cgtcgcccac gcgatgatcg cgctgctgac cggggcgtcc gcgccgccgg ccggcaccat
    10981 ccggggagtc aacctgatcg ccgcggacca ccatgtgcgg gtcagccatc cgccccgccc
    11041 cggctgcccg gtctgcggga cccgggtgcg cgcccgtttc aattcgaatg ggcgcatttc
    11101 gccggcatga ccgaaacagc gattaccaca acgaattgac agaatcattg actgcgtgcc
    11161 atcggcggcg aatcatgaac gcgttctcgc gagaacatcc ccgtccctca cccacgagag
    11221 gaaccggatg acccccaacg agcacgagat cgaaaccgcc gacgaggcgg ccccgccggt
    11281 caagacgaaa atcaccatcc ggctgctcga caagatcgag acgacgaacg ccagcaacag
    11341 cgtcggcaac tgacgccggt gccgccaccg tggtgtgcgg gcgcgcagcg ggagcgcccg
    11401 cacgccgcag gcggtcgtgc cgcaccggcc ccgcggcccc gcgccgcacc gcgacggacg
    11461 gcccgaggga gggaagggtg gcatccaccc gcaccatctt tgacgacgta cggcaggccg
    11521 aggcgcgggt gctgcccgcc gacgcctacc aggccgagtt cgccgaggag ttcgcccggg
    11581 cgaccggcgt ggtgtggaag ctcgaacgcg cccaggagtt ccgcgaaccc gacgtcccga
    11641 gctggcgggc gatgatggcc ggtgactggg aacgttccct cgccctgatc gcggagatgc
    11701 gggagcccct caccggctac taccgcaccc gcccggcgac ccgcaggctc cgtgtcgtgg
    11761 agaccccgct caccccctat ctccagtggg aactgcgcgt cctggccgtc agggcggagg
    11821 ccggggagcg tccacgggtg ctcgccgccg gcgccgtacg ggagttcgag cgcaccgcgc
    11881 cgctccccga gcttgtcgcg atcggctcgt cgctcctcta cgaggtgctg tacgacgaga
    11941 tcggtgggca cgtcggcgcc cggcggatca ccgacccgga cctcgcgggc ccctgtcgcg
    12001 ccgcgatcga gacgctctac cagcggggag aggacgtgcg ggcgtacgtc gagcgggagg
    12061 tcctcccgct gccgcctccc tcggcctcct cccggtcgcg cggcacctac cgcccctgaa
    12121 ccccgcgcct ggaggccgcg atgagtcagg acgccgggcc gccggcggat gggacccggg
    12181 tccggctgcg cgacctcgcg ttccggcggg acggctccca gtggatcgtc ggccgcccgg
    12241 acgggcagga gttcgccgcg gtgccgtacg aggggatgcg ggccatcagg ctgctgatgg
    12301 agggcgcgac catcgaggag gccgaacggc ggctgcgcgg cgagacgggc gccgacctcg
    12361 acgtccggga cttcgtccgc gccctcggcg agctgggttt cctggacgag ccgggcaggc
    12421 cggccgcccc ggccgagccg ccgacgttcc cccggctgcg cgcccggcac gtgcggtgga
    12481 cgctgagccc gctgctccac acggcggtgg ccggcgtgat cgccgccggg acggtgacgg
    12541 cggtgatcag gcgggagacg ctgccgggct ggcaggacct gctgtggagc gagcacggca
    12601 cgctcgtcct gctctccgag atcgccgtcg gctggacgct gatcttcctg cacgagatgg
    12661 cgcacctgtc gaccgccagg gcggccgggg tgccgggccg gatccgcctg ggcacgcggt
    12721 tgcagttcct ggccgtccag accgaggtgt ccgggatctg gctggccgag cggcgcgtcc
    12781 gcctgacggt ctatctcgcc gggatggccg tcgacgcggc ggcctgctcg gccgcggtca
    12841 tcctggccgc cgtcctgggc cgccacaccg tgctgtccct cgtcacgctg acctcggtgt
    12901 ccatgctgac cacccagttc ctggtgttca tgcgcaccga cgtgtacttc ctgctgcagg
    12961 acctgaccgg ctgccggaac atgtacggcg acgccaccgc ctacgcgcgc catcgggtgc
    13021 tccggctgct cggcagaccg acgcccgacc cgctcgccgg cctgccccgg cgggagcgcc
    13081 gcagcctccg ggcgtacgcg gtgctgatgg tcgtgggcac cgtggtctgc ctcggagtgg
    13141 cgttcgcggt cacgctgccc gcgacgctcg tcctgctctg ccgggcggtg cgcgcgctcg
    13201 gcacccccgc cacgcccctc tccgtcctgg acgccgcggc ggtgctgctg gccgcgctcg
    13261 cgttccaggt ggcctgggcg cgggcctggt ggcgcaggca cggcccccgc ctgcgccgca
    13321 cactcccccg cacccgcacg cggccgtagc cgcccgaggc catggccgtc gcgcaggggc
    13381 tcccatcgat actcgtgtaa aaaattctgt acacgaggtc aaagattggc taccttggag
    13441 atgtcaaaga tgttgtacat cgagaggagc cgctcatgac tcacctggag aagcgcgcct
    13501 ggatcaggct ggtcgtcgcc gtgctcgcct acgcggcgta cgtcgtcgtc gtcctcagac
    13561 gggcggacgg gggcccgtta cccgacacgc cgtacaccgc cgccctgctg tggtcggtcg
    13621 gcggggccat cgccgccacg atcgcggccg agatcgggat ggcgatcgtg aacccccgcg
    13681 cctcccgcgt gcaggacgcg cgtgaccggg agatcgggcg gttcggcgac cacgtcggcc
    13741 aggcgttcgt cgtgatcggc gcggtggccg cgatgctcat ggcgatggcc gggtgggacc
    13801 ggttctggat cgccaacgtg gtctacctct gcttcgtgct gtcggcggtc ctcgccggga
    13861 tcgccaaggt cgtcgcctat cgcaggagcc ttccggaatg gtgaagccga cccgcgtgac
    13921 caaccgcatc cgcacgctgc ggttcacgca cgacgagatg acccaggccg agctcgccga
    13981 gcgcgtcggc gtgacccggc agaccctcat cgccatcgaa cagggccgat actccccgtc
    14041 actggagatg gccttccgga tcgcccgcgt gttcggcgtt ccgctcgacg acgtgttcca
    14101 gtaccccgac ctccccgagg agacgccatg aaagccatcg tccaggacgc gtacggcccg
    14161 gcggacgtgc tccgcctgag cgacgtcgac cgccccgaga tcggtgccga ggaggtgctc
    14221 atcgaggtcc gcgccgccgc ggtggacccc ggcgtgtggg tcctcatgac cggccggccg
    14281 tacctcatgc gcctcgcggg cttcgggctg cgccggccga aggtggtggt ccggggccgt
    14341 gacgtggccg gggtggtggc ggccgtcggc gccggagtga cccggttccg gccgggtcag
    14401 gaggtgtacg gcacctgtac gagcggctcg tacgcggagt tcgcgagggc gcggcagaac
    14461 aggctcgcgc cgaaaccggc cggcctcacg ttcgagcagg ccgccgcgat gccggtctcc
    14521 ggcatgacgg cgctgcaggc cgtgcgcgac gtcgccggtg tgcgcccggg gcagcgggtt
    14581 ctggtgatcg gcgcctcggg aggcgtgggg tcgttcgccg tgcagatcgc cagggcgtac
    14641 ggcgcgagcg tcaccggcgt gtgctcggcg gcgaaggcgg gcttcgtgcg gtcgctcggc
    14701 gccgacgacg tcgtcgacta cgcccaggag gagatcgacc gggacgggcc gcgttacgac
    14761 gtcgtcgtcg acaccgccgg aaaccggccg ctgtccctgc tccggcgcgc cctgacaccg
    14821 cgggggacgc tggccgtcgt cggcggcggg cacgtggccc accgcttcac cgggggcatg
    14881 ggacgcacgt tccgggcgcc gctgctgtca ccgttcaccg ggcagcggct tcgcccggtc
    14941 atgacgcgag agcgcgccga ggacctggag gaactgaccc ggctcgccga gtccggcgcc
    15001 gtcaccccga tgatcgaccg ggtctatccc ctcgccgacg cgcccgacgc gatccgtcac
    15061 ctcatggggg gacacccggg cggcaaggtc gtcgtcaccg tgaacgggac ggcctgaggc
    15121 acggcggaag cgtcggtggg cggctctagg caaaagtgat atcactttgc tagtgtcttg
    15181 ctagacatcg aggagcgtgc acatgacaga cctgcagatc gccgtcgaca tgccggcccc
    15241 ccagacgcac gagagagcgg cccgcgaaac cgggggatgg ccgatgctga tcctggccct
    15301 gctgggcctg ctgagcccct tcgtgctggt cccggtcgga atcggcatcg cggccgacgg
    15361 gagcggcggc ccgggggccg tgctgatcat cgccggggtg ctgctcctcc tggtggccgt
    15421 cgtcgccttc accgggctca ccgcggtcgc tccgggcgag gcgcgcgtga tccagttgct
    15481 cggccgctac gtgggcacgg tccgtacgcc cggcctccgg ttcgtggtgc ctttcacgca
    15541 gaagcgccgg gtgtcgaccc ggatccgcaa ccacgagacc gacgtcagca aggtcaacga
    15601 cgccgacggc aacccgatcg agatggccgc ggtggtggtc tggcaggtgg aggacaccgc
    15661 gaaggccgtc ttcgaggtgg acgacttcgt ggagttcgtc gctttccaga ccgagacggc
    15721 ggtccgccac atcgcgggca gctaccccta cgacgggcac gacgacgtgc tctccctgcg
    15781 ccagaacgcc gacgagatca ccggccgcct gtcggccgag atccaggccc gggtggcctc
    15841 ggcgggggtc cgggtgatcg agtcgcgcat cacccgactg gcgtacgccc ccgagatcgc
    15901 gcaggccatg ctccgccgcc agcaggccgg agcggtcgtc gcggcgcgtc agcggatcgt
    15961 ggagggcgcg gtcggcatgg tcgaggccgc cctggcccgc ctcgacgagc acgacgtgat
    16021 cgaactggac gaggagcgca aggccaccat ggtcagcaac ctgctcgtcg tcctgtgcgg
    16081 cgaccgggac gtgcagcccg tggtcaacac cggttccctc taccgctgac cgtggcgacc
    16141 gaccggaaga gcatcctgct gcgactggac cccgccgtgc acgacgcgct ggcccggtgg
    16201 gccggtgacg aactacgcag caccaacgcg cagatcgagt tcctgctccg ccaggcgctg
    16261 gcggacgcgg ggcggcttcc ccgcgaggcc gcccgcatcc cccggcgcgg ccggccgccc
    16321 aggacatcgg ctccgcccaa cggctccgcg gcctcccaga agcccgacga gcccgaaggc
    16381 ggagctccgc ccggagacga ctgagagaag gcgacctcat gaacgttccc ggctccctgc
    16441 cggcccggct ctacctgctc ggctacgacc cccgtaagga gcgggtggtg acgaactatc
    16501 gcttcccgta cctgctccgc gccgccgcgc tcaccgagct gctcctcgag ggccggatcg
    16561 ccgacgagcg cggcaaggtg cgggtggtga gcgagcagcc gctcggcgat ccggtcctgg
    16621 acgacctgct gcaccagatc gccgggtccc gccccaagcc gtggcggcac tggatcgaca
    16681 aggacggccg cgcgacggtc cgggcggtcc gggacgagct ggagacgcgg cactgggtcc
    16741 gcgtggagct gcgccagccg ttcctcctgg tcttcaacag gacccgggtg cgcgtgcgcg
    16801 atccgcgcgt ggtgaagcgg ctcacgacgc aggtcgccac cgcgctcaac ggtcccatgt
    16861 cccgggtcgg cgaacgggag gccgccctgg tcgcgctggc cgccgcggga gagctccgga
    16921 cggtgctgcc acgtgccagg cggaaggcgt acaagcagcg catcgccgag ctgggcgaac
    16981 gcggcggacc ggcgacgccc gccctgcgca aggtcatcca gcaactgcac gcggcgtccg
    17041 ccgccgccat gagcgggggc ggctgacccg cccgcacgac gcggccccgg cgttccgagg
    17101 cggccggtcc cggcgggggc gtcactgtgc ggcgaggcct ggggcgatcg tgcgcagcgc
    17161 ctcggcgagg tcggcggcgg acggcgcctc gtcgggatcg acgagccact gcgccgccat
    17221 gccgccgagc agcgcctggt agaacgcgcc gacggccatc gccttccgcg ggtccgcggc
    17281 cgggtcgagg ttctcgaaga gcgccgcgag tcccagcttc gcctggcggt tggccgtcgc
    17341 gaaggcctcc cgcagctcgg gcaggcggtc catctgcgcg atgagctcga actggatggc
    17401 ccacaggggc ctgagcctgg cgaaggactc gatgatccgg gtccaggtgg cctcgaaccg
    17461 ctgcgcgggc gtcccgccga gcgccggtcc ggcggcgagg gtccgctcga tctccttgcc
    17521 ccactcctcc atcgcatcga cgagagccgc gttgagcagc gccttcgtcg acctgaagtg
    17581 gtagccgatg gaggcgaggc tggtgccggc cgcggtcgcg atgtcacggg cggtggtgcc
    17641 ggagtacccc ttctccatca ggcatcgcct ggcaccggcg agcaggtctt cccggtttcc
    17701 catgcgcaga tcctaaccga ttcacggact gatgtctgag acatatgtac tagacaaaat
    17761 attgagacgt ttgtacagtc cgagtcgtga cgaacatcct gatctccggc ggaagcgtcg
    17821 ccgggctgac gctggcgtac tggttgcgtg agtacgggtt cacccccacc gtcgtcgagc
    17881 gcgctccccg cctgcgggag ggcggctaca aaatcgacat ccggggcgcg gcactcgacg
    17941 tcgtcggccg catgggcctg ctggacgagg tgcgcgggca cagcacggac atgcgcgtcg
    18001 cacgcttcgt cgacgcccgg gggaagcagg tcgcgacgat gaacgccgag gtgttcggcg
    18061 gccgcgaggg cgacgacgtc gagatcatgc gcggcgacct cgtccggatc ctgcacggcg
    18121 cggccggaga cggtgtcgag tacgtcttcg acgactccgt caccgccctg gagcggacgc
    18181 ccggaggggt gcgcgtcacc ttcgagagcg gtcccccgag gacgttcgac ctggtggtgg
    18241 gtgccgacgg cctgcactcc aacgtccgcg cgctggcctt cggcgaggag tcccggttcg
    18301 tccgcgacct cgggcaccac atctcgatct tcacggtgcc caaccacctc ggcctggacc
    18361 gcaccgagat gatgcacccc gcgccgggcc ggagcgccgg gatgtacggc acccggcgag
    18421 acgccgacgc cagggcgatg ttcctgttct cctccccgcc gggggccggc gacgggcggg
    18481 acgtcacccg gcagaagaac ctgctcgccg aggtcttcgc ggaccagggc tgggacgtcc
    18541 cgcgcctcct cgacgccatg tgggacgcgc cggacttcta cttcgactcg atcagccagg
    18601 tgtgcatgga cggctggtcg tcgggccgag tggccctcgt gggcgacgcc gcctacgggc
    18661 cctcccccgc gtccgggcag ggcaccagcc tggccctggt cggcgcctac gtgctggcgg
    18721 gcagcctcgc cgccgcggcc gcagaccaca ccgccgggtt cgccgcgtac gagcgtgaga
    18781 tgcggcactt cgtcgaggag aaccagaagc tcgcggcccc caacatcaag ggcatggtgc
    18841 tgaggtccgc ggcgcagatc cggttccaga tgctgatgct gcggctgatg ccgcacctgc
    18901 cggggaagga ccggatgatc gagcgggtca ccgggccgat ccgccgggcc gcgaccgcga
    18961 tcacgatccg ggactaccgg gtcccgtcgg tgtgagccgt accgccgggc cgacaggcgg
    19021 ggcctctcgg gcggggcttc tcagcggggc ttctggggcc gcccggaatg acggtgcgcc
    19081 cggctgcgcc cccacggcgg aaccgggcgc accgagccgg ccccggactc cggcgacagg
    19141 agggggcgaa cccacatccg ccgtcgcgag gccggtgctc gcgcgggtcc ggtgggtccg
    19201 ccgcctcctg gtgggcggcg ccgtcagggc gccgccggtc tcacgagccg gtgcaggtga
    19261 cggtgggagt cgacgccgta ccgttggcga ggaagccgaa cgtcgtcgac gcggacggcg
    19321 cgagcgagcc gttgtacgag gcgttgctca cggagaccgt cgagccgctg gtggtcagcg
    19381 tgccgttcca gacctggctg atggtctggc cgccggccag ggtccacttg acggtccagc
    19441 cgctgatcgc ctcgcttccg gccgtcacgg tgacctctcc ctggaacccg ccggaccacg
    19501 tgttggtggt gcggtaggtc gcgctgcagg cgccggtgac cggcggagtc ggcgtgcgcg
    19561 tgggcgtggc cgacggtgac tgcgagggcg actgcgacgg ggactgcgac ggggactgcg
    19621 acggcgactg ggagggcgac tgcgacgggg actgcgaggg cgtggccgaa ggcgacggct
    19681 ggccgttgcc gctgaactgc caccagttca cgttgaacag gttgccgctg ccgccggtga
    19741 acttgaggta caggtcgtgg gtgccggtcg cgccgttcac cgagcaggag acggtggtcc
    19801 aggtctgcca cccgccggtg ccggagacgt tgcacgtgcc gaccagggtg ccgttgacgc
    19861 cgtccaggtg cagctcgatc ttgccgccgg agttggcgga ggcgacccgg gcgctgaagg
    19921 acgtcgcgcc ggagccgaag gcgaccccct tgaccttgat gtagtcgccg ttctcgatga
    19981 acccgacgtt catgccgccc tcggtggagg cctcggtctc cacacccgac tcccacgcga
    20041 tcgtctcggc ctcctgccgg acgtacgggt tgagcgtgcc gatctgcggc gccccggtcg
    20101 tggtcatgtt gatcgtcgga atcgacccgt cagagccgta ggtgaacttc tccaccgcca
    20161 ccgagcgcgt gtatccgccg ccacccggca acgcaccgtt gtggtagaag aaatacgacc
    20221 cgccgttgta gtcgatgatc cccgggtggt tggtgaaact gctgccctgc gtcgacatga
    20281 tcgtgccgcg gtaggtccac ggcccggtcg ggctggagga ggtcgaatag gcgatgaact
    20341 ccgagcagca cttggccgcg aacaccatgt agtagaggct gccccgcttg tagaaccagg
    20401 gcccctcctc gaacagcgtc ggccggttgg cgtccccggt gcgggtgccg aagcccgacg
    20461 tggtcaaggt gaccttcgtc gcgctgcccg agtaggagat catgtcgctg ttcagcttga
    20521 cgtaccacag gttcgggttg ccccagtaca gataggcctg cccgttgtcg tcgatgtaga
    20581 cggtcgggtc gatctccccg ttttcgacca gcgggcgccc gatggcgtcc ttgaacgggc
    20641 cggtggggct gtcggagacg gccacgccga tggccatccg gccggtcgag cggttggtcg
    20701 tggggacgta ccagtagaac ttgccgttgc ggtagaccgc ctggcccgcc cacgcgtccg
    20761 acttcgccca gctgaaggtg gccacgctca gcggggagcc gtggtcggtc cagttcacca
    20821 tgtcggtggt ggagaagacc cgccagtcct tcatcgtgaa gtaggtcgag ccgtcctcgt
    20881 cgtgaccggt gtagaggtac acccgcccgt tgtagaccag cggggccggg tcagcggtgt
    20941 agatcgtctg cacgatgggg ttgtccgcct tggccgtcgt ggccggcagc aacgccgcca
    21001 tgcacaacag gcccgccatc cagacgacac cacgcctgag ccgggcccga agggtgaacg
    21061 ccgatcccat actcacctcc tggggtagtg accacgcgac ttgcgcatcg
//
