LOCUS       NZ_CP048835            82336 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8241504
            Orig. end                         :: 8323840
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..82336
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /candidate_cluster_numbers="4"
                     /contig_edge="False"
                     /product="T1PKS"
                     /product="T2PKS"
                     /product="azole-containing-RiPP"
                     /region_number="25"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /rules="(t2ks and t2clf)"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..82336
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /detection_rules="(t2ks and t2clf)"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="neighbouring"
                     /product="T1PKS"
                     /product="T2PKS"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="3"
                     /tool="antismash"
     cand_cluster    1..42952
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42952
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:22952](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..22952
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    520..538
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    525..535
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            1244..1876
                     /locus_tag="C8250_RS36755"
                     /old_locus_tag="C8250_036785"
     CDS             1244..1876
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS36755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_036785"
                     /product="hypothetical protein"
                     /protein_id="WP_138354179.1"
                     /transl_table=11
                     /translation="MTGRPGLPGRARSWSQRFADRLEAIGATVPPGPPAAGVTGLEVEA
                     GAVTARVREGQARYDVRIGLAEFTPAQWTRAVRAVGADPDCRARLLDNELAPDAEDLFA
                     RAGLRLFPARTPDLAMECSCPDWALPCAHLSAVLRSLADAFDADPYLVLTWRGRTREEL
                     LKELPPAVPRREPADSALLLLGRPAITVRGRGLTEVLGPAYEAFTGW"
     misc_feature    1975..1990
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     gene            2001..2762
                     /locus_tag="C8250_RS36760"
                     /old_locus_tag="C8250_036790"
     CDS             2001..2762
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013866.4"
                     /locus_tag="C8250_RS36760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036790"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_138354178.1"
                     /transl_table=11
                     /translation="MEFEIVRESITIPSGDGSMGAHLVRPQAPGRYPGVVVGFEIFGLT
                     AHIRDVAERIARLGYTVIVPDFYHRAGTGIDFTDDPDGRVKGLELSGGLTREGAVEDIR
                     AAVDHLRGAELAAPSVGMIGFSFGGHLAYLAATQFDLAATAVFYAGWLASSDIGLGRPG
                     PTLTLTEGIAEHGGRLAFFVGDEDHAVPAADRAAIGARLAEAGVRHEIIVYPGIPHGFF
                     CDVRDSYRKEAADDAWIRVQELFAAELPRPA"
     misc_feature    2837..2851
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 21.84"
                     /tool="antismash"
     gene            3040..5103
                     /locus_tag="C8250_RS36765"
                     /old_locus_tag="C8250_036795"
     CDS             3040..5103
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020141320.1"
                     /locus_tag="C8250_RS36765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036795"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_138354177.1"
                     /transl_table=11
                     /translation="MPRPPTPRRFTPRALIATGAVTATAAGLLVAVAGTGSAAPVLLSQ
                     GKPATSSSDGGTGYAAKLAFDGDTATRWASVRNVDPQWIRVDLGTAATISSVKLVWDLS
                     CATAYKVEFSTDGSTWKSVYSTTTGDGGTDDLAVSGTARYVRTTGTARCRPTMGYSLQE
                     FQVFGGGSADTQPPTTPGNLHSTGSTPTSAALAWNASTDDAGVAAYDIYNDGNKIAEAA
                     GTATTKNVTGLTPNTAYRFTVFARDAAGNVSPASNLATVTTPPSSDTRPPTAPGGLAVT
                     GTTSGSASLKWTAATDDTGVTGYDVYNGTDVILPDVTGTTATVSGLAADTSYTFTVKAK
                     DAAGNVSPASNQVTAKTLPDSGSDKTPSSIKTVSTGWTIPWGMSWLPDGSALITERDSF
                     KVFKLTQAGARTQIGTVPNAVTTDGEGGLLGIAVSPNWSSDHYVYIMHTASEGNRIVRM
                     TYDGSTLSGYTQLVGGIKKSKYHNGGRLKFGPDGYLYATTGEAQTPDLAQDKNSLNGKI
                     LRMTTAGKAAPGNPFGTLIYSYGHRNPQGITWDPQGRLWEAEFGNSKYDELNLITPGAN
                     YGWPTCEGKCSTSGMTNPKAQWAVAQASPSDIAYSDGAIYMAALKGQRLWRIPVSGTTA
                     GTPAAYYVNQYGRLRTVEKIPGKSALWLSTTNCDNNGNAADGADKVFQIELK"
     gene            5445..6425
                     /locus_tag="C8250_RS36770"
                     /old_locus_tag="C8250_036800"
     CDS             5445..6425
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983554.1"
                     /locus_tag="C8250_RS36770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036800"
                     /product="lysylphosphatidylglycerol synthase transmembrane
                     domain-containing protein"
                     /protein_id="WP_138354176.1"
                     /transl_table=11
                     /translation="MTLAQAERVKWQGGWQRTSVRSMAVLIPVLALAVLAGRRWSLIDS
                     SADQLGAADRQWLAVAAAAAVMTWICSATAQQGAVVESLPPGRLLATQFAASAANHLLP
                     AGVGGNAVNLRFLLRRGLPPGRSAAALGVRAVAAAVVRVGMLLILLAVFPHALKVDRVT
                     PAGPAHPVVIVSVVAGCAVAGALLLLLAGRVRDRVRTFFGTMVVDVRALHCKSARVAAL
                     WGGSLAFPVMHATVLVAVIQALNAPVPVSGVVLAYLFASTAAAWLPAPGGLGSLDAALA
                     FTLVTAGASAVVATSAVLGYRLVTVWLPLIPGVLVLAALMRRRVL"
     gene            6493..7215
                     /locus_tag="C8250_RS36775"
                     /old_locus_tag="C8250_036805"
     CDS             6493..7215
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053680.1"
                     /locus_tag="C8250_RS36775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036805"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138354175.1"
                     /transl_table=11
                     /translation="MVEPRVDPAGRGRVLVVDDDAAIRRSLGRGLRLDGFRVTEADGGR
                     AALAGLRDDPPDVVVLDISMPGISGIEVCRTLREDGNDIPVLMLSALDEVADRVAGLQA
                     GGDDYLVKPFALDELVLRLHALLRRRPPRRTDTVRAGGLLLDPAARTAHLDGTELHLTR
                     REFELLETLARNAGIVLTRDQLLDRVWGYDFDVRTDAVDTFVSYLRRKLEAGGRSRIVH
                     TVRGVGFVLRDSPAEGAR"
     gene            7212..8738
                     /locus_tag="C8250_RS36780"
                     /old_locus_tag="C8250_036810"
     CDS             7212..8738
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014139261.1"
                     /locus_tag="C8250_RS36780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036810"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_306665030.1"
                     /transl_table=11
                     /translation="MTMRLSTRIAIAVGVLVPLLVLASGWLLVRLVANDLHAQADAHLR
                     ERAAAMAQDARNLLRVTAADRSAAAEQAKEKRLFTSALDVGIRLIGPDGTVTGGPQPGA
                     SFTLPADARRPVTVRDGQRSWRVLSVPVVAKRPAATGTLWIFSPDTASQSQIQLVRRRV
                     VMVALLGAPLAAAVTWLAATAAVRPLRRLQRRAAGLDPGTSAARLDHEPSRIAEVDDLA
                     LTLRTVLSRYDEQAARTAEALATARSFSAAASHELRTPLMSMRINLDVLGGHPGLDPAE
                     RAEIVADLSREHARLLGLLVMLRALAQGDLVEADAFGPVDLAEVVESAAAALRGSRPGT
                     ALTVRSGPGLLVHGWEPGLRSAVDNLIVNALTHGGGAVDVTLSAGEDGHGPGEVAGPFV
                     VLTVDDDGPGVPPASRQRVFERFRRGSDSSGSGLGLTLVAQQISLHRGTIRILDRPAGE
                     GRAARGARFEVRLPLAVTGRPDSGLPSRRDWLSGETATGTGPVTGPVTDR"
     misc_feature    8840..8856
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            8840..9232
                     /locus_tag="C8250_RS36785"
                     /old_locus_tag="C8250_036815"
     CDS             8840..9232
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949923.1"
                     /locus_tag="C8250_RS36785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036815"
                     /product="hypothetical protein"
                     /protein_id="WP_138354174.1"
                     /transl_table=11
                     /translation="MRTTRTTRTAIAACAAVAALLGAAGSAAAAPSAPPTGDGAKAVCK
                     RAPKADARIDKALARLNGNAATKGSVARLTQRVANAKSAGHSEIETYLNDRLTFRKSLV
                     PTLQQRQKDLKSVLVWCQANNSGTSK"
     gene            9229..9453
                     /locus_tag="C8250_RS36790"
                     /old_locus_tag="C8250_036820"
     CDS             9229..9453
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS36790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_036820"
                     /product="hypothetical protein"
                     /protein_id="WP_138354173.1"
                     /transl_table=11
                     /translation="MTTGSRLAAVTATVLLCAALATGCGDKGGGADGSATIPTPSGSQL
                     AHLDKVVGDAESAANAAESDAASDAASDN"
     gene            9490..10341
                     /locus_tag="C8250_RS36795"
                     /old_locus_tag="C8250_036825"
     CDS             9490..10341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016575301.1"
                     /locus_tag="C8250_RS36795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036825"
                     /product="hypothetical protein"
                     /protein_id="WP_232485764.1"
                     /transl_table=11
                     /translation="MARTLWLRTEPLHAVVYFDAQCREMGRSLGLKGYWMGYFATRSAP
                     LGRAQPSVVTAAFGVFAPGPVARALPASWDITTPERALDLRVERSAAALRALDPELERR
                     AERLTGPLGAMVADAPALARPVFAANRALPDRADPVEQVWQLTTSLREFRGDAHLAVLA
                     DRGLDGCEALLLAAADGRVPADSIRQDRGWTAEEWAGAGARLRERGLLAAGGALTERGR
                     DERRSIEDDTDRLAGRLLRPLSGDRAQALFSDLAPVVDRVLAGQVLPFPNPIGLPRPVR
                     PL"
     cand_cluster    9815..82336
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(t2ks and t2clf)"
                     /kind="single"
                     /product="T2PKS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    9815..82336
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[44814:47336](+)"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="2"
                     /t2pks_malonyl_elongations="11|12 (Score: 696.8; E-value:
                     1.6e-212)"
                     /t2pks_molecular_weights="malonamyl-CoA_11 (Da): 833.332"
                     /t2pks_molecular_weights="malonamyl-CoA_12 (Da): 875.369"
                     /t2pks_molecular_weights="hexadienyl-CoA_11 (Da): 842.382"
                     /t2pks_molecular_weights="hexadienyl-CoA_12 (Da): 884.419"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_starter_units="malonamyl-CoA (Score: 610.0; E-value:
                     0)"
                     /t2pks_starter_units="hexadienyl-CoA (Score: 132.0;
                     E-value: 9.14e-37)"
                     /tool="antismash"
     proto_core      44815..47336
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(t2ks and t2clf)"
                     /neighbourhood="35000"
                     /product="T2PKS"
                     /protocluster_number="2"
                     /t2pks_malonyl_elongations="11|12 (Score: 696.8; E-value:
                     1.6e-212)"
                     /t2pks_molecular_weights="malonamyl-CoA_11 (Da): 833.332"
                     /t2pks_molecular_weights="malonamyl-CoA_12 (Da): 875.369"
                     /t2pks_molecular_weights="hexadienyl-CoA_11 (Da): 842.382"
                     /t2pks_molecular_weights="hexadienyl-CoA_12 (Da): 884.419"
                     /t2pks_product_classes="pentangular polyphenol"
                     /t2pks_starter_units="malonamyl-CoA (Score: 610.0; E-value:
                     0)"
                     /t2pks_starter_units="hexadienyl-CoA (Score: 132.0;
                     E-value: 9.14e-37)"
     gene            complement(10385..12109)
                     /locus_tag="C8250_RS36800"
                     /old_locus_tag="C8250_036830"
     CDS             complement(10385..12109)
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006261 - DNA-templated DNA replication
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034492.1"
                     /locus_tag="C8250_RS36800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036830"
                     /product="bifunctional 3'-5' exonuclease/DNA polymerase"
                     /protein_id="WP_138354171.1"
                     /transl_table=11
                     /translation="MSTPLPSAPRVAVAPDPVGHGGRLLVLDEEGVPTGSAERVADLAA
                     AIAAREASGGPRWVWAATEDLYPRLLDRLPVRPARCHDLKLVETLLLGRDGRHGQPRSL
                     GAAWARLKDLPVPEDAREGAADDQPVLFAADRHHLPQDADPLTAVVAVHAEQQRRLQEG
                     EHPGRMRLLCAAESAGSLAAAEMGRGGLPWSAAVHDELLTGLLGPRPSGGARPKLLGEL
                     ATQVQEALGSPVNPDSPAQVLPAFARVGVQLPSTRSHVLREVEHPAAALLLRYKELSRI
                     HAAHGWAWRESWVRGGRFRAEYVVGGVVSGRWATRGGGALQIPRLLRSAVVADPGHRLV
                     VADAGQLEPRVLAAMSADTGLAAAAAEGDLYAGIARTAFGGDRSRAKIGLLAAMYGQTS
                     GEAGQLLAILRRRFPDAMGLVESAARIGEGGGVVRSRLGRTSPTPASGWLDTEDADLGS
                     GSGSGSGSDDGSSPDRRAARSWGRFTRNFIIQASASDWALAMLAATRRRLAAIGPEPQL
                     VFFQHDEIIVHTPTGLAGPVEAAVAAAGEEARRLVFGDTPVRFPLETNVVECYADAK"
     gene            complement(12162..13892)
                     /locus_tag="C8250_RS36805"
                     /old_locus_tag="C8250_036835"
     CDS             complement(12162..13892)
                     /NRPS_PKS="Domain: AMP-binding (34-432). E-value: 5e-67.
                     Score: 218.2. Matches aSDomain:
                     nrpspksdomains_C8250_RS36805_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605408.1"
                     /locus_tag="C8250_RS36805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036835"
                     /product="AMP-binding protein"
                     /protein_id="WP_138354170.1"
                     /sec_met_domain="AMP-binding (E-value: 2.2e-63, bitscore:
                     213.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSTHTAGAAHTPDTGSAAGTTVAELVRARWKDHRPGLKYRDLVL
                     THHETAAASAARAALLRDLLPPGAQPHVGVLLDNVPEYPLWLGAAALAGATVVGVNPTR
                     RGPELARDIAHTECALLVTERAHLPLLDGLDLGPSLARDRVLVVDDPAYDALLAPYAGA
                     EPEPAPEVTPGTRMLLYFTSGSTGTPKAVICSQGRLAHAGQALVDFLGVVPEDVHYICM
                     PLFHGNAVMANWAPALTGGAAVALTRKFSASGFLPDIRAYGATYFTYVGRAVQFLLATP
                     ERPDDRDHPLRHGFGTEAGAVDATRFAARFGAPLIEGYGSSEGGAAIQRSPGTPPGAIG
                     RAAPGADLAVVDPGTGRERPPARFDADGRLLNGDEAIGELVNRGRSTFEGYWKNEQAVA
                     DRLRGDWYWTGDLFFRDAEGFFHFAGRSDDRLRVDSENLAAAVIENILARFPDAASAAV
                     YAVPDPVAGDQVMATLALHDGAAFDPAAFAAFLAAQPDLGTKMPPRFVRVTARMPVTAT
                     NKVHRVGLRRTGFSCADPVWWSPPDAGPCGAAYRPFTTADRMALLDEYRAQHRDTLLDR
                     "
     aSDomain        complement(12597..13790)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36805_AMP-binding.1"
                     /evalue="5.00E-67"
                     /label="C8250_RS36805_AMP-binding.1"
                     /locus_tag="C8250_RS36805"
                     /protein_end="432"
                     /protein_start="34"
                     /score="218.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RPGLKYRDLVLTHHETAAASAARAALLRDLLPPGAQPHVGVLLDN
                     VPEYPLWLGAAALAGATVVGVNPTRRGPELARDIAHTECALLVTERAHLPLLDGLDLGP
                     SLARDRVLVVDDPAYDALLAPYAGAEPEPAPEVTPGTRMLLYFTSGSTGTPKAVICSQG
                     RLAHAGQALVDFLGVVPEDVHYICMPLFHGNAVMANWAPALTGGAAVALTRKFSASGFL
                     PDIRAYGATYFTYVGRAVQFLLATPERPDDRDHPLRHGFGTEAGAVDATRFAARFGAPL
                     IEGYGSSEGGAAIQRSPGTPPGAIGRAAPGADLAVVDPGTGRERPPARFDADGRLLNGD
                     EAIGELVNRGRSTFEGYWKNEQAVADRLRGDWYWTGDLFFRDAEGFFHFAGRSDDRLR"
     CDS_motif       complement(13308..13358)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36805_0001"
                     /evalue="4.90E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS36805"
                     /protein_end="195"
                     /protein_start="178"
                     /score="19.2"
                     /tool="antismash"
                     /translation="LYFTSGSTGTPKAVICS"
     gene            complement(14001..14369)
                     /gene="trxA"
                     /locus_tag="C8250_RS36810"
                     /old_locus_tag="C8250_036840"
     CDS             complement(14001..14369)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0015036 - disulfide oxidoreductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="trxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308334.1"
                     /locus_tag="C8250_RS36810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036840"
                     /product="thioredoxin"
                     /protein_id="WP_138354169.1"
                     /transl_table=11
                     /translation="MSTVELTKDNFDEVVTKNDFVLIDFWAAWCGPCRMFAPVYEKAAE
                     ANPDLVFAKVDTEAQPELAASFDIQSIPTLMIVRDRVAVFAQPGALPAAALDDVIGQAR
                     ALDMDEVRKSVEQAQQGS"
     gene            14480..14695
                     /locus_tag="C8250_RS36815"
                     /old_locus_tag="C8250_036845"
     CDS             14480..14695
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712520.1"
                     /locus_tag="C8250_RS36815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036845"
                     /product="hypothetical protein"
                     /protein_id="WP_138354168.1"
                     /transl_table=11
                     /translation="MGTTEWARDSGGANDGAAWRVTRGGTIPHGSDVPVYAALADQWRS
                     AGRMVPGQIDAEWAELVGRIPRLTGV"
     gene            complement(14779..15645)
                     /locus_tag="C8250_RS36820"
                     /old_locus_tag="C8250_036850"
     CDS             complement(14779..15645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123155.1"
                     /locus_tag="C8250_RS36820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036850"
                     /product="thermonuclease family protein"
                     /protein_id="WP_138354167.1"
                     /transl_table=11
                     /translation="MPMLVIEGTYRITGARPDGDSIRFYPTDPAHWDLVEGKHRVQRNA
                     TGGAQLRLDAIDALETHYIPAHGHELHQPAPYADQAAGELLSWLGFTGVTRDGHGTVSA
                     AEPAQLPGYLLSRGADLYGRCVALVGKGAAPGTSGERIRVEAALLEETANFHQLAEGLA
                     YPTYYRNLYVDLRQALTAAVDAARSKGVGLWSLDVTQSGARIDGLESITSEAVIMPKLF
                     RRLADYLALGAGDPSLAGFAAFLDQRGDRVLIVSRGQYTGFETVVEVSGQTVRMNRPPE
                     DLVFDEG"
     gene            15957..17771
                     /locus_tag="C8250_RS36825"
                     /old_locus_tag="C8250_036855"
     CDS             15957..17771
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468348.1"
                     /locus_tag="C8250_RS36825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036855"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_138354166.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.2e-12, bitscore:
                     45.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-12, bitscore:
                     47.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTVLRRAGAGEGALAVPQLRHSSWELAARFDRELGDPGDPATVF
                     SYQEAVRLDDAEEFPDEACAALDAWGLADYYVPADYGGVLTGFEDLQQLIRMLARRDLT
                     VAVGHGKTFLGSVSVWVSGDHAAAVRLGALVKAGARVSLGLTERTHGSDIMAGELTAEP
                     VGPGYRVNGEKWLINNATRGRLLSLLARTSPVGGPRGFTLLLLDKEELPEETYRCLPKV
                     PTHGIRGADISGVVIQDAVVGPEAVVGGAGGGAELLLKSLQLTRTLCPSLSLGAADHAL
                     RLAMEFASERVLYGRRLTELPLTRRTLAEAYADLLVCEALSTVATRSIHALPSELSVTS
                     AVAKYLVPTIIDGQVASLGSLLGARSFLSGEFAHGSFQKVARDHRIVGIFDGNTLVNQY
                     SLVAQFRSLARNYLGPLDHRPRLGTLFNLSRPLPPFDPERLTLLSRYGSSVLGTLPASV
                     TRLADAALLDPALGGAARCAAELRVAADALHRRIARRMETVAAASPESFTDARKYGLCF
                     AGAACLGLWLHSHREAEAGGTGGLWQDGLWLEAVLNRLLARLEARPAAGAAEDPLFERL
                     YTQLTQQYQDGSLFSLLPCPIAEGPPSC"
     gene            17765..19573
                     /locus_tag="C8250_RS36830"
                     /old_locus_tag="C8250_036860"
     CDS             17765..19573
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478988.1"
                     /locus_tag="C8250_RS36830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036860"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_138354165.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.9e-10, bitscore:
                     39.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.7e-11, bitscore:
                     42.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKDNSSRPQPGPVPDAGPAQPAGLRSVDPAEVAIQARVAELEQL
                     LGDPRDPDNPFGHDALLAADDRSELLPSAEDALTGFGLNHEFVPVELGGRLARVDTLAR
                     VLRPVFRRDASLALGYGVTSFLAAVAVWAAGTPEQRRWTADLLMGGGRLAIAYHELAHG
                     NDFVRNEFTALPDGTGFRLDGRKEVINNAGRAEALVLFSRTAKEAGARSHSVLLVDKSV
                     LPADRFEHLPRYRTVGVKGCEIGGFHFRDCPLPGDALVGGLGEGVEIALRSFQITRSAI
                     PAMVLAGADTALRTVVGFAVDRQLYGRSVLEIPHARSTVAGAFTDLLICDSLALAATRA
                     VHLLPGQTSVYAAVVKYLVPKFLQDATYDLSIVLGANFYVRNGEYGIFQKHVRDLPMTS
                     LGHAGTAACQATIIPQLPRLARKSWFAGEPAPASLFRSWEGLPPLDTSRLSLAADGDAL
                     AASLVTGYDWLRATGSGGTDAAALIELVRSLVEELRELQGECTEMPPEDRTVLASPHAY
                     ALADRYALVLAGSAVLNVWREQLGGGSPFLADPAWPTAALARIARRLGLPVPERTRDEV
                     DWLLGEVLDRYHGERSYDLYDSPLAG"
     gene            19603..20004
                     /locus_tag="C8250_RS44980"
                     /old_locus_tag="C8250_036865"
     CDS             19603..20004
                     /NRPS_PKS="Domain: ACP (15-84). E-value: 6.6e-19. Score:
                     60.0. Matches aSDomain: nrpspksdomains_C8250_RS44980_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="C8250_RS44980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036865"
                     /product="acyl carrier protein"
                     /protein_id="WP_138354164.1"
                     /sec_met_domain="PP-binding (E-value: 3.7e-13, bitscore:
                     48.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVPGSAVQEREFRGWLLEKLGQYLRRPPADIDISVPFAEYGIDS
                     VAALSIFGDIEDGFGLYLEPTVAWDHPTVQSLARYLASESARSATGPLTQAPYGEPIGG
                     NQAGGDPSDPRDTPGTAGWTRNTPGGGPR"
     aSDomain        19648..19854
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS44980_ACP.1"
                     /evalue="6.60E-19"
                     /label="C8250_RS44980_ACP.1"
                     /locus_tag="C8250_RS44980"
                     /protein_end="84"
                     /protein_start="15"
                     /score="60.0"
                     /tool="antismash"
                     /translation="WLLEKLGQYLRRPPADIDISVPFAEYGIDSVAALSIFGDIEDGFG
                     LYLEPTVAWDHPTVQSLARYLASE"
     gene            20001..22952
                     /locus_tag="C8250_RS36840"
                     /old_locus_tag="C8250_036870"
     CDS             20001..22952
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (3-418). E-value:
                     1.1e-150. Score: 494.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS36840_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (523-800). E-value: 5.7e-92.
                     Score: 300.2. Matches aSDomain:
                     nrpspksdomains_C8250_RS36840_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_PP (893-977). E-value: 4.1e-09.
                     Score: 28.7. Matches aSDomain:
                     nrpspksdomains_C8250_RS36840_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) AT (Score:
                     181.8; E-value: 4.1e-56)"
                     /gene_functions="biosynthetic-additional (t2pks) AT
                     AAP85359.1_Hedamycin_hexadienyl-CoA (Score: 132.0; E-value:
                     9.14e-37)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478984.1"
                     /locus_tag="C8250_RS36840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036870"
                     /product="type I polyketide synthase"
                     /protein_id="WP_138354163.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.6e-73, bitscore:
                     244.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 1.5e-148, bitscore:
                     494.3, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.1e-90, bitscore: 300.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.1e-07, bitscore:
                     28.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPIAVLGLDCRFPGAPDPGAYWDLLAAGADGVGPRPASRRVGDT
                     RRASVPAARPDGGFIDDADAFDHAFFGIGRAEAAAMDPQQRLLLQTAWRALEDAGINPR
                     DLAGSGTGIYVGAMADDWSRLRLADDAAITPRTGTGAGRAILANRLSYQLDLRGPSLTV
                     DSACSSALIAVHLAMGALLSGECDIALACGVNLVMSDVLDEIYGQSGLAAPDGRCKPFG
                     AQANGIGRAEGVGAVVLQRLEGARDEGRPVRALLLGSAVNQDGRSNGIMAPSRRAQREV
                     IQAACKRAGVEPQRIGWVEAHGTGTPVGDLIEARALGDVYGGLRPEPCAISSVKGNIGH
                     AEGAAGIAGLIKAVLALEHRLVPPVRTVGGEHPGLDLAAHGLRLLTEPLPLPEGEMLAA
                     VSSFGMGGSNAHVVLSSAPRQTAPIAAPQTNNGESGESPGVFTLTAPTAEALRRNLVVQ
                     ARSLAARAQEPVTPLCWTSNLTRTGMAYRIAIPAEDTAGLAAALDAAAEAGEGVPEPPE
                     PPVVAFLFTGQGAQYPGMTSRLYRESPLYRHYLDEASRALEPHLGGSITELLLGRDERV
                     HRTGWTQPAVFAVQYALAGYLEELGVRPGAVLGHSIGEFAAAVTAGALGLEDAAALVAA
                     RGTAMEALPEGGGMLAVRAHPDDLREVLAGEPLVGLGAANGAAASVLSGDLAGLARIRE
                     QLAARGVGCTPLKVSHAFHSVLMEPVLPGFRTTADGITAGEPRIPFFSTVRGGLLAGRP
                     LDADYWCEHITGSVRFADAAAALLGSDVTHLVELGPKPVLLPLARRLPGGSGLPGISVV
                     RDAHSGALTAAEAAAALYTAGVDIRWELLYRPEDKVHAQLAPQSFDTSARFWYEPPRPA
                     AAPAGEPGSPVLSLVRADSGPRAPEHDGGGLAEAVRETVAGITGAEEGTLRDDDRFYDD
                     LGFDSVMFMELKYRLEEAVPALGELSIPEMMSSLVSVTTLIGYLREQLARVPA"
     aSDomain        20010..21254
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36840_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.10E-150"
                     /label="C8250_RS36840_PKS_KS.1"
                     /locus_tag="C8250_RS36840"
                     /protein_end="418"
                     /protein_start="3"
                     /score="494.3"
                     /tool="antismash"
                     /translation="IAVLGLDCRFPGAPDPGAYWDLLAAGADGVGPRPASRRVGDTRRA
                     SVPAARPDGGFIDDADAFDHAFFGIGRAEAAAMDPQQRLLLQTAWRALEDAGINPRDLA
                     GSGTGIYVGAMADDWSRLRLADDAAITPRTGTGAGRAILANRLSYQLDLRGPSLTVDSA
                     CSSALIAVHLAMGALLSGECDIALACGVNLVMSDVLDEIYGQSGLAAPDGRCKPFGAQA
                     NGIGRAEGVGAVVLQRLEGARDEGRPVRALLLGSAVNQDGRSNGIMAPSRRAQREVIQA
                     ACKRAGVEPQRIGWVEAHGTGTPVGDLIEARALGDVYGGLRPEPCAISSVKGNIGHAEG
                     AAGIAGLIKAVLALEHRLVPPVRTVGGEHPGLDLAAHGLRLLTEPLPLPEGEMLAAVSS
                     FGMGGSNAHVVLSSAP"
     aSModule        20010..22931
                     /complete
                     /domains="nrpspksdomains_C8250_RS36840_PKS_KS.1"
                     /domains="nrpspksdomains_C8250_RS36840_PKS_AT.1"
                     /domains="nrpspksdomains_C8250_RS36840_PKS_PP.1"
                     /locus_tags="C8250_RS36840"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       20472..20519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0001"
                     /evalue="1.70E-05"
                     /label="PKSI-KS_m3"
                     /locus_tag="C8250_RS36840"
                     /protein_end="173"
                     /protein_start="157"
                     /score="17.0"
                     /tool="antismash"
                     /translation="GPSLTVDSACSSALIA"
     CDS_motif       20664..20690
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="C8250_RS36840"
                     /protein_end="230"
                     /protein_start="221"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="GAQANGIGR"
     CDS_motif       20895..20939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0003"
                     /evalue="5.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="C8250_RS36840"
                     /protein_end="313"
                     /protein_start="298"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VEAHGTGTPVGDLIE"
     CDS_motif       20997..21038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0004"
                     /evalue="4.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="C8250_RS36840"
                     /protein_end="346"
                     /protein_start="332"
                     /score="9.9"
                     /tool="antismash"
                     /translation="SVKGNIGHAEGAAG"
     aSDomain        21570..22400
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36840_PKS_AT.1"
                     /evalue="5.70E-92"
                     /label="C8250_RS36840_PKS_AT.1"
                     /locus_tag="C8250_RS36840"
                     /protein_end="800"
                     /protein_start="523"
                     /score="300.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGAQYPGMTSRLYRESPLYRHYLDEASRALEPHLGGSITEL
                     LLGRDERVHRTGWTQPAVFAVQYALAGYLEELGVRPGAVLGHSIGEFAAAVTAGALGLE
                     DAAALVAARGTAMEALPEGGGMLAVRAHPDDLREVLAGEPLVGLGAANGAAASVLSGDL
                     AGLARIREQLAARGVGCTPLKVSHAFHSVLMEPVLPGFRTTADGITAGEPRIPFFSTVR
                     GGLLAGRPLDADYWCEHITGSVRFADAAAALLGSDVTHLVELGPKPVLLPLARRL"
     CDS_motif       21573..21620
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0005"
                     /evalue="6.30E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="C8250_RS36840"
                     /protein_end="540"
                     /protein_start="524"
                     /score="18.6"
                     /tool="antismash"
                     /translation="FTGQGAQYPGMTSRLY"
     CDS_motif       21747..21782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0006"
                     /evalue="5.30E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="C8250_RS36840"
                     /protein_end="594"
                     /protein_start="582"
                     /score="9.9"
                     /tool="antismash"
                     /translation="QPAVFAVQYALA"
     CDS_motif       21801..21923
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36840_0007"
                     /evalue="1.10E-19"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="C8250_RS36840"
                     /protein_end="641"
                     /protein_start="600"
                     /score="62.6"
                     /tool="antismash"
                     /translation="GVRPGAVLGHSIGEFAAAVTAGALGLEDAAALVAARGTAME"
     aSDomain        22680..22931
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36840_PKS_PP.1"
                     /evalue="4.10E-09"
                     /label="C8250_RS36840_PKS_PP.1"
                     /locus_tag="C8250_RS36840"
                     /protein_end="977"
                     /protein_start="893"
                     /score="28.7"
                     /tool="antismash"
                     /translation="APEHDGGGLAEAVRETVAGITGAEEGTLRDDDRFYDDLGFDSVMF
                     MELKYRLEEAVPALGELSIPEMMSSLVSVTTLIGYLREQ"
     gene            22982..24010
                     /locus_tag="C8250_RS36845"
                     /old_locus_tag="C8250_036875"
     CDS             22982..24010
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358477.1"
                     /locus_tag="C8250_RS36845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036875"
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="WP_138354162.1"
                     /sec_met_domain="fabH (E-value: 1.7e-30, bitscore: 105.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLLAAATALPGPAIGNEVLAGRLGLSAEWVEMFIGTRTRHFAVD
                     LAGGVGCLLADLCEQAAVRSLERAGLTVRDLSFVVLATATPDSLMPTTAAVVADRLGAA
                     GIPAYQLQSGCSGAVQAFTLAEALLAQQPAGPGGPYGLVLGGDVCAKHLDLEQDFRRMP
                     PAQLVNYVIFGDGAGAAVVSAAPAPGSAAFHGLGNRLALPGQPPGQHVEWYGAADRDSA
                     LPPVSEDYKAVEFLVPELAQQVCADLLDTLGWSAPDLGYLLPPQLGGLMTRRITAALRA
                     GLGVEKAVEISCVADTGNTGNALVLSQLEQLLPLLTPGARALCACVESSRWISAGFALE
                     AS"
     gene            24048..24275
                     /locus_tag="C8250_RS36850"
                     /old_locus_tag="C8250_036880"
     CDS             24048..24275
                     /NRPS_PKS="Domain: PP-binding (9-68). E-value: 8e-07.
                     Score: 21.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS36850_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468342.1"
                     /locus_tag="C8250_RS36850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036880"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_138354161.1"
                     /sec_met_domain="PP-binding (E-value: 0.0001, bitscore:
                     21.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVEDMITLLNQELGLFLRPEDAGSPLDALPGWDSLLLFRLVAV
                     LEEEAGRPLPVAEVVTAGTLAEIHALAVGL"
     aSDomain        24075..24251
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36850_PP-binding.1"
                     /evalue="8.00E-07"
                     /label="C8250_RS36850_PP-binding.1"
                     /locus_tag="C8250_RS36850"
                     /protein_end="68"
                     /protein_start="9"
                     /score="21.3"
                     /tool="antismash"
                     /translation="LLNQELGLFLRPEDAGSPLDALPGWDSLLLFRLVAVLEEEAGRPL
                     PVAEVVTAGTLAEI"
     gene            24272..25183
                     /locus_tag="C8250_RS36855"
                     /old_locus_tag="C8250_036885"
     CDS             24272..25183
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959531.1"
                     /locus_tag="C8250_RS36855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036885"
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_203673877.1"
                     /transl_table=11
                     /translation="MTPQAASGQAGTGRTTARQDTARSDRARRHTRYFLRWARAAAPVH
                     LGADIDMTGVQAHRAAARAEGRRYSVVSYLLYAAGRVLADHPEANATTAGGIVPRTLRY
                     ERVHAKLAIDSGTADEGRRAVRVAVLPDVDRLDLAGIQQLVDRYRNGAAEDLPGAEGVR
                     RLGRLPPPLGHLAFRTAVSSGARRAELLGTVAVSSLGHRRVDTFHSYGGTAVTLTAGRI
                     AEVPVARATRVAVAPVLRLGLTFDHRVLDGAAAADVLDDLALLLEACDAALPGGWDAPQ
                     RRSGDRPAHQGDQSGRPVAPRG"
     cand_cluster    24281..48233
                     /candidate_cluster_number="4"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="3"
                     /tool="antismash"
     protocluster    24281..48233
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[34280:38233](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      complement(34281..38233)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="3"
     gene            25176..26003
                     /locus_tag="C8250_RS36860"
                     /old_locus_tag="C8250_036890"
     CDS             25176..26003
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (133-173). E-value: 1.2e-06. Score:
                     20.2. Matches aSDomain:
                     nrpspksdomains_C8250_RS36860_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004994425.1"
                     /locus_tag="C8250_RS36860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036890"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_244809605.1"
                     /transl_table=11
                     /translation="MVEALDERGSVMVHALLSDWVPENLDDPELRPVLGRDWHRYQAMR
                     HHHVRERFAASRLLLKHVAAQAIQAPPATVELAYKPGGRPYLRGCDQIDISLSHTEELL
                     LVGITRRGWIGVDAELEDRSMLVSGIERQVCTPYERTMLSQVRESDRNQEMVRLWTLKE
                     AYSKAIGQGMRFRFNEFGFGPSGHPVQVLRPDGSPGTGEEWAFGTCRVEGRYTASWALY
                     DAGFGDTDDTRAGTMLDEGLVTALLHQPAEAPQPAAEATAATDVPLTGAGVAA"
     aSDomain        25575..25694
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36860_ACPS.1"
                     /evalue="1.20E-06"
                     /label="C8250_RS36860_ACPS.1"
                     /locus_tag="C8250_RS36860"
                     /protein_end="173"
                     /protein_start="133"
                     /score="20.2"
                     /tool="antismash"
                     /translation="VCTPYERTMLSQVRESDRNQEMVRLWTLKEAYSKAIGQGM"
     gene            26000..27274
                     /locus_tag="C8250_RS36865"
                     /old_locus_tag="C8250_036895"
     CDS             26000..27274
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 92.0; E-value: 1e-28)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468339.1"
                     /locus_tag="C8250_RS36865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036895"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_138354159.1"
                     /transl_table=11
                     /translation="MTAAPPPAGTDVVVVGGGPAGLALALALVRLGVRTTVLERSAGGR
                     RDFRGESLSPDGVRLLDRCGVLEQLRAIALPVRRLEVADGGRTVLDVGFESFPYPYRFP
                     LEIPQSLLLAEIEAAARCQDGFRMLRGWTAKGLLSADGRITGVRAAGPGGVECEIRARL
                     TVGADGRYGRIRKLAELDARVRPLDRDVIWMRLPRPVEWTDAAYRIRIRGDRHALLLPD
                     SGGTVRVGLNIPKGGLRELRRSGLDALHERLGELAPELAEPARQTLRDWSDTALLDIFS
                     TTVPHWSAPGIVLIGDAAHTLSPVLGQGVNHALADATALAPLAAAALHSGEPAGLDRAT
                     GQFQRQRSREVARSRRLQLRQERIFTWSAPAAVAVRRGVYRALDRSARLRARMLEPAYF
                     ADQRAERARGARREDHDEHEQEART"
     gene            27271..28347
                     /locus_tag="C8250_RS36870"
                     /old_locus_tag="C8250_036900"
     CDS             27271..28347
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018234.4"
                     /locus_tag="C8250_RS36870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036900"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_138354158.1"
                     /transl_table=11
                     /translation="MTTRLGADDAIGLEELRGLSLLHAQAQGIEPGAAQELLARITEPW
                     GDRPRSWGRVWSAEGDRLTGQGLHLEASRHYAMARFPYPGDAPRQEAQRRCVAAFDTWR
                     AEQGAGIERLEVPLEDGTAVCWTAGLSATDPKPLIVVMGGIVSVKEQWAPLLVHAEAFG
                     VALAVTELPGVGENTVPYGPRSPRMLSAILDALSGRADVSRTAAIALSFGGHLALRCAL
                     VDSRLACVATVGAPLRLFFEDEAWQRQVPRTTLAALAHTTGVPPSLVFGYTRGWGLTDE
                     ELGALRIPVHYIAALRDEIVPLGEAAVLRRAAVPGEVTVLDDVHGAPAHLDHTRGLLLG
                     AALAAAAPATPGAVPEAA"
     gene            28347..28829
                     /locus_tag="C8250_RS36875"
                     /old_locus_tag="C8250_036905"
     CDS             28347..28829
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025445.4"
                     /locus_tag="C8250_RS36875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036905"
                     /product="DUF4260 family protein"
                     /protein_id="WP_187145134.1"
                     /transl_table=11
                     /translation="MTLNPRGATAPPVTHTASRGRPPTPPSAPATARWSGAPATWAHRH
                     PVGRAVSLAVGLGALGGAVALGGRHDKVLWFCAVAPDTALLLGIAGAPTWHRMPSYAVR
                     PYNVLHSPAVPAVLLTAAALTGRRRLAVAGLAWLGHIGWDRACGYGPRDAAGYVTR"
     gene            complement(28819..29988)
                     /locus_tag="C8250_RS36880"
                     /old_locus_tag="C8250_036910"
     CDS             complement(28819..29988)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468336.1"
                     /locus_tag="C8250_RS36880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036910"
                     /product="cytochrome P450"
                     /protein_id="WP_244809607.1"
                     /sec_met_domain="p450 (E-value: 1.3e-20, bitscore: 72.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTYPPPRPSATQVPPAYEELRAGCPVARVTLPSGDPGYLVSRYE
                     DVREVLGGADFSRAATVLPEAPKLTAMPFDAGGLFTLDPPEHTRLRALVTAEFTAGRVR
                     ALRPRIEQAAERLVDEMITAGEGVDLIGAYAFPLPAFVICELLGVPYEDRDRFRGWSDA
                     LLSLTAHSPEVMRANRDELVGYLADLVGAKRLEPGDDLLSALVQAHDEHGSLSHLELLT
                     MAMTLLVAGHETTAGMIGTCAFTLLREPDGFAALLRRPASVVEELLRYNPMGDGGPLRV
                     TLRDTEVAGVPIPANSAVIASICSANRDERVFPDADSFRPGRPGPSHLAFGHGVHHCLG
                     APLARAELEIALTTLARALPKLRLAVPEQDITMHTGLLVNRLTALPVTW"
     misc_feature    complement(29984..29996)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    complement(30095..30109)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.64"
                     /tool="antismash"
     gene            30198..30494
                     /locus_tag="C8250_RS36885"
                     /old_locus_tag="C8250_036915"
     CDS             30198..30494
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039972.3"
                     /locus_tag="C8250_RS36885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036915"
                     /product="DUF6059 family protein"
                     /protein_id="WP_138356856.1"
                     /transl_table=11
                     /translation="MSQLAKWSVTYFLGPVYRALVTYGTFYVPITPYLYPSGRTAGLGR
                     QQRKPGHDYADPIAGYAGPADGHPETVRPDVPLSAFEREAARQLGLVHEFERP"
     misc_feature    complement(30589..30603)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     gene            30601..32328
                     /locus_tag="C8250_RS36890"
                     /old_locus_tag="C8250_036920"
     CDS             30601..32328
                     /NRPS_PKS="Domain: CAL_domain (30-468). E-value: 8.1e-140.
                     Score: 458.7. Matches aSDomain:
                     nrpspksdomains_C8250_RS36890_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383356.1"
                     /locus_tag="C8250_RS36890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036920"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_138356861.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 7.7e-223, bitscore:
                     741.7, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-91, bitscore:
                     305.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQQAQARTGQEAFAFTGEGRDGAATVDRITYGRLDREARRLGAW
                     LQDHNAAGKRVLILQDQGPLFIACFLGCLYAGAVAVPAPPPGGTRRHIERVAGIVKDSA
                     ASFALTDSRHAPVISQLLAEAGHGDVVCLATDALPADAIAPADPDDWRRPDLSLDDLAF
                     LQYTSGSTSEPKGVMISHRNLLANQRAIQRAMGTGARSRIGGWLPFHHDMGLVGHLLHP
                     LWLGAQGVIMPAMSFVRRPVRWLQMVSEYGITTGGGPNFAYELCVQRVTDEQVAELDLS
                     RWENAVNGAEPVRAETLCAFAEKFKPAGLDPSALYPCYGMAEATLLVSGGIPGSRAPQL
                     PVDAGALERHRLEDPMPGRSVRTLVGSGLVRDFDLRIVDPESGRVKMPGAIGEIWIRGD
                     SVAQGYWNRPAETAYSFQAVTSTGESGFLRTGDLGVVRDGELFVTGRLKDVMIVAGRNL
                     YPQDVERTVQRVSALFSSTVVFAVDSDREHVVVVQEVRSGRTFDADLPGLVSAVQQSVS
                     REFAMPVRNVVLVRPGTVRRTTSGKLQRAAMRQLFLTDRLRPLHEVVDPDLKRLVRHG"
     aSDomain        30691..32004
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36890_CAL_domain.1"
                     /evalue="8.10E-140"
                     /label="C8250_RS36890_CAL_domain.1"
                     /locus_tag="C8250_RS36890"
                     /protein_end="468"
                     /protein_start="30"
                     /score="458.7"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="TYGRLDREARRLGAWLQDHNAAGKRVLILQDQGPLFIACFLGCLY
                     AGAVAVPAPPPGGTRRHIERVAGIVKDSAASFALTDSRHAPVISQLLAEAGHGDVVCLA
                     TDALPADAIAPADPDDWRRPDLSLDDLAFLQYTSGSTSEPKGVMISHRNLLANQRAIQR
                     AMGTGARSRIGGWLPFHHDMGLVGHLLHPLWLGAQGVIMPAMSFVRRPVRWLQMVSEYG
                     ITTGGGPNFAYELCVQRVTDEQVAELDLSRWENAVNGAEPVRAETLCAFAEKFKPAGLD
                     PSALYPCYGMAEATLLVSGGIPGSRAPQLPVDAGALERHRLEDPMPGRSVRTLVGSGLV
                     RDFDLRIVDPESGRVKMPGAIGEIWIRGDSVAQGYWNRPAETAYSFQAVTSTGESGFLR
                     TGDLGVVRDGELFVTGRLKDVMIVAGRNLYPQDVERTVQ"
     CDS_motif       31084..31143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36890_0001"
                     /evalue="8.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS36890"
                     /protein_end="181"
                     /protein_start="161"
                     /score="27.6"
                     /tool="antismash"
                     /translation="AFLQYTSGSTSEPKGVMISH"
     CDS_motif       31762..31848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36890_0002"
                     /evalue="1.00E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="C8250_RS36890"
                     /protein_end="416"
                     /protein_start="387"
                     /score="43.4"
                     /tool="antismash"
                     /translation="PGAIGEIWIRGDSVAQGYWNRPAETAYSF"
     gene            32476..33081
                     /locus_tag="C8250_RS36895"
                     /old_locus_tag="C8250_036925"
     CDS             32476..33081
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005478956.1"
                     /locus_tag="C8250_RS36895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036925"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138356855.1"
                     /transl_table=11
                     /translation="MIHVLLAEDMHMVRGALVALLNLEVDIKVIAEVESGDEIVPTSVR
                     TRPDVAVIDIDLPGIDGLTAAADLHEQMPSCRTLILTSLGRPGNLRRALDAHVSGFILK
                     DAPPAKLAQAIRSVRAGERVIDSQLALAAWDTGENPLTRREVEVLRLTANGAEAVEIAA
                     RLFLSVGTVRNYLTTILAKLNARNKVDAIRIARDAGWL"
     gene            complement(33098..34165)
                     /locus_tag="C8250_RS36900"
                     /old_locus_tag="C8250_036930"
     CDS             complement(33098..34165)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="C8250_RS36900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036930"
                     /product="histidine kinase"
                     /protein_id="WP_232485772.1"
                     /transl_table=11
                     /translation="MLGYLLLGIVSMLARQVPTSEMAWGAGILVALFLLQNLHSLPNRG
                     GDRPRYWIWTLSMQGLLTYIPFLILKDSWVGMPGYFAGSLLLFLRGKVSWLSASAVAIS
                     MFFIEQHLGSDGFSAFYYACGVGTIGLSVFGLTRLGDLLVEVQAARAELARLAVARERD
                     RVARDLHDLLGYSLSAITLKGELVYRLVNSHPERACEEISTMLAISRQALSDVRMVASS
                     YRDMSLAAEIAATRAVLVSADIATVVTVDCGPLEDRVNTVLSTVLREGVSNLLRHSKAQ
                     NCVIEAILDKGVVRLRVENDGLNTSPSVTARRDGRGLDNLCTRLGELGGTLNAAAAEDG
                     WFRLTALVPLSGAAA"
     misc_feature    34218..34232
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.69"
                     /tool="antismash"
     gene            complement(34281..35912)
                     /locus_tag="C8250_RS36905"
                     /old_locus_tag="C8250_036935"
     CDS             complement(34281..35912)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: goadsporin_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="C8250_RS36905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036935"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_138356853.1"
                     /sec_met_domain="goadsporin_like (E-value: 1.1e-164,
                     bitscore: 547.7, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 8.3e-12, bitscore: 44.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHSEPRPDVGTDLRRVSLWSLREDVHLERASSAGGAVLHSRWGDV
                     LLTGPDELVYESLRRMSFGPVDLENILRATPRPHGEITASDRARLLTLLDSVSYLVVRS
                     LGLDDTEPQLLDMVPIARGARLDIRAVPPDQPIRLSRFAVLQTKDELLVLDSALSLHRA
                     QFRRPEAAWVIGVLGKATTLKAATAALPVAEGVVADIIAYLAAAGMVTLGEQDGNGVVV
                     FAEDHDPSLITWTPNELLFHTRTRLGRHDGDFGATFPYLGQLSPEPAVKSAPDGVRIPL
                     YRPDLDTVLAADPPLTAVLETRRSTRTYAEEPLSDRQLGEFLYRIARIRSLYSSIGLEP
                     ASYPASSRPYPSGGSAYELECYITLSRCVGLAAGNYYYDPYGHCLVRLDDPSNSAAELL
                     AQASAAAGMTTTPQVLITITARFRRLSWKYSGMWYALALKHVGVVQQTMCLVATAMRLA
                     PLPLGSGDIETSAQAFGLDWREESSIGELLLGPLAPDDTSAEAESAMGYPVNDSDWGER
                     CAATAGHVQPVASSLPARPGAQHDDR"
     gene            complement(35951..38233)
                     /locus_tag="C8250_RS36910"
                     /old_locus_tag="C8250_036940"
     CDS             complement(35951..38233)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468333.1"
                     /locus_tag="C8250_RS36910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036940"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_138356852.1"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 4.7e-16,
                     bitscore: 57.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 2.9e-12,
                     bitscore: 45.4, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 5.7e-14, bitscore:
                     50.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3e-89, bitscore: 299.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 7.2e-82, bitscore:
                     274.1, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEFKAHLRAEVIPGEGTYLFSERDVKMIDCPQLELMAPLMDGRR
                     GINEIIRDAGRELAPEQIGYVLAQLANAALVDFRRTARTLENPARTGLAFWELAGLDGA
                     QTAARLADGSVRILTVGAVDGSAVRAALQATGVSVHATSAVTGSSCGIPGADLSVVVCD
                     DYLASELAAVDASHRAAGRPWLLAKPHGADIWLGPVFQPGEGPCWNCLAHRLRGHREVE
                     NHVQRTLGRSGPLLIPQASIPPSQGVGLHMVALEAAKWMAGHRYHGQQSVLTLDNFTMT
                     ARHHAVQRRPQCAFCGDPSLSTERIGRPLPLRSRSKAYANGSGDRSASPENVLARYRTQ
                     VSPLTGVVSRLDPDPAAPPGLQVYRAGHNMALGTPGLRSLRHGFRGMSAGKGVTSVEAE
                     VGALCEALERFSGVFTGEELRVRDSLRNLGEPAIHPNRCQLFDERQYADRDRWNAAHGD
                     FQQVNEEFDVTADVDWTPVWSLTEQRQRLLPTSMLYYNTPESSGGFCSADSNGCAAGSS
                     LEDAIVQGFLELVERDSTALWWYNRTRHPGLSLSAFEEPWIAERRSLYAGRNRELWALD
                     LTADFGIPAVAALSRRTDKEDEDIVIGLGAHFDMRVALRRALTELDQMLPFVMNARPDG
                     GGYECSGNDILDWCRTATVANQPYLLPDPLAPMSTPDDYPYTAHPDLLDDVMGIQRLVE
                     AKGMELLVLDQTRPDIGLPVVKVIVPGLRHFWARFAPGRLFDVPVLLGRRTTPLGYENL
                     NPVPLFL"
     aSDomain        complement(37931..38230)
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C8250_RS36910_Goadsporin_CD_RRE.1"
                     /evalue="1.50E-18"
                     /identifier="RREFam013.1"
                     /label="C8250_RS36910"
                     /locus_tag="C8250_RS36910"
                     /protein_end="101"
                     /protein_start="1"
                     /score="57.6"
                     /tool="antismash"
                     /translation="TEFKAHLRAEVIPGEGTYLFSERDVKMIDCPQLELMAPLMDGRRG
                     INEIIRDAGRELAPEQIGYVLAQLANAALVDFRRTARTLENPARTGLAFWELAGL"
     aSDomain        complement(37979..38227)
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C8250_RS36910_NHLP_CD_RRE.1"
                     /evalue="1.90E-16"
                     /identifier="RREFam015.1"
                     /label="C8250_RS36910"
                     /locus_tag="C8250_RS36910"
                     /protein_end="85"
                     /protein_start="2"
                     /score="50.9"
                     /tool="antismash"
                     /translation="EFKAHLRAEVIPGEGTYLFSERDVKMIDCPQLELMAPLMDGRRGI
                     NEIIRDAGRELAPEQIGYVLAQLANAALVDFRRTARTL"
     aSDomain        complement(38006..38227)
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C8250_RS36910_Cyanobactin_D_RRE.1"
                     /evalue="9.30E-15"
                     /identifier="RREFam007.1"
                     /label="C8250_RS36910"
                     /locus_tag="C8250_RS36910"
                     /protein_end="76"
                     /protein_start="2"
                     /score="45.4"
                     /tool="antismash"
                     /translation="EFKAHLRAEVIPGEGTYLFSERDVKMIDCPQLELMAPLMDGRRGI
                     NEIIRDAGRELAPEQIGYVLAQLANAALV"
     gene            complement(38270..38515)
                     /locus_tag="C8250_RS36915"
                     /old_locus_tag="C8250_036945"
     CDS             complement(38270..38515)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS36915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_036945"
                     /product="hypothetical protein"
                     /protein_id="WP_138356851.1"
                     /transl_table=11
                     /translation="MDAIEQDWRFAELVALSWIEPALSLRYAQNPSQVLAEFGLHVAGD
                     VSTPALPPAPQLALVIEDFTGEMKARGSVSCFCAKG"
     misc_feature    complement(38447..38449)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    38622..38636
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.49"
                     /tool="antismash"
     misc_feature    complement(38712..38725)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.86"
                     /tool="antismash"
     misc_feature    38797..38810
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            38800..39609
                     /locus_tag="C8250_RS36920"
                     /old_locus_tag="C8250_036950"
     CDS             38800..39609
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014135874.1"
                     /locus_tag="C8250_RS36920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036950"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_138356850.1"
                     /transl_table=11
                     /translation="MEINVLGPLTASEAGTSIVPSAAKPRQILAVLALNANHVVTVARL
                     MEELWGSDLPRSAPTTLQTYILQLRRKLSAALGSVTGAKDVLATRHSGYQLSMDSAAID
                     AWQFDQLTVAGYAAYEAGDVARASRRLSDALNLWRGPALVDLQHGTLLEVEVMRLRESR
                     LAALERRLDADLAMRRHHELLGELAGLTAEFPLHENLHAQFMLALYRCGRPSQALEAFR
                     RLRSGLVDELGLEPSARVQRLQRAILSADPVLDGVHPGAVVGVASIG"
     gene            39748..40467
                     /locus_tag="C8250_RS36925"
                     /old_locus_tag="C8250_036955"
     CDS             39748..40467
                     /NRPS_PKS="Domain: Thioesterase (5-218). E-value: 6.8e-32.
                     Score: 103.6. Matches aSDomain:
                     nrpspksdomains_C8250_RS36925_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="C8250_RS36925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036955"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_138356849.1"
                     /sec_met_domain="Thioesterase (E-value: 9.9e-31, bitscore:
                     106.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARLRLFCFHHAGGGAMSFARWQNRFGSDISVIPVRLPGRETRL
                     REERVTDGEQLSRELEAELGPFLDRPYALYGHSLGALVAYSFALHHHRSGGRPPEVLTV
                     GACSAPHLGMPDLEGAEGSDERVLSVMRASGGITSQLLDRPQWLQLTMAIMRDDLLLAA
                     GLRAAAGDPLPCPVLAVSGQDDLLVPPGAVHAWSRYAPEGFRTGSVPGDHLFVRDADLA
                     DLLRAELEERRPLEPAI"
     aSDomain        39763..40401
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36925_Thioesterase.1"
                     /evalue="6.80E-32"
                     /label="C8250_RS36925_Thioesterase.1"
                     /locus_tag="C8250_RS36925"
                     /protein_end="218"
                     /protein_start="5"
                     /score="103.6"
                     /tool="antismash"
                     /translation="RLFCFHHAGGGAMSFARWQNRFGSDISVIPVRLPGRETRLREERV
                     TDGEQLSRELEAELGPFLDRPYALYGHSLGALVAYSFALHHHRSGGRPPEVLTVGACSA
                     PHLGMPDLEGAEGSDERVLSVMRASGGITSQLLDRPQWLQLTMAIMRDDLLLAAGLRAA
                     AGDPLPCPVLAVSGQDDLLVPPGAVHAWSRYAPEGFRTGSVPGDHLFVRD"
     CDS_motif       39766..39792
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36925_0001"
                     /evalue="3.80E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="C8250_RS36925"
                     /protein_end="15"
                     /protein_start="6"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LFCFHHAGG"
     CDS_motif       39955..40011
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36925_0002"
                     /evalue="6.40E-07"
                     /label="NRPS-te1"
                     /locus_tag="C8250_RS36925"
                     /protein_end="88"
                     /protein_start="69"
                     /score="21.9"
                     /tool="antismash"
                     /translation="RPYALYGHSLGALVAYSFA"
     gene            40489..41331
                     /locus_tag="C8250_RS36930"
                     /old_locus_tag="C8250_036960"
     CDS             40489..41331
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358463.1"
                     /locus_tag="C8250_RS36930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036960"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_138356848.1"
                     /transl_table=11
                     /translation="MDIGVLGPCRVTQAGQSVVPTAIKPRKVLALLALQPDRVVSVSSL
                     IEELWGGNPPRSVQTTLQTYILQIRNLITRSLAGEDQRDLPLGAKSVLVTEAGGYLLDT
                     QGGVVDSVEYERLAGAGHRALESGDHSGAALLFQQALALWRGPALVDVQVGPLLEAEVT
                     RLEESRMSILSQRIEADLQLGRHHEILGELAGLAAQHPTHERLQGQLMLALYRAGRRGG
                     ALEAYHRMRVVLGRELGLDPSAALQELQQAMLASDPGLECDPVGSLTGGGPLRVVRAG"
     gene            complement(41365..41733)
                     /locus_tag="C8250_RS36935"
                     /old_locus_tag="C8250_036965"
     CDS             complement(41365..41733)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358453.1"
                     /locus_tag="C8250_RS36935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036965"
                     /product="SchA/CurD-like domain-containing protein"
                     /protein_id="WP_138356847.1"
                     /transl_table=11
                     /translation="MPFAAITYDIKAGYEKEIGEIFGGFRRVGSPVVEGADGAETTRIL
                     ATAVFIRDATMVRVIEYEGDLQDVARFMASQPGVQEVERKLAPYLSRPRDTGTPEGFIA
                     TFNRSLLTCLTQISARES"
     gene            complement(41907..42440)
                     /locus_tag="C8250_RS36940"
                     /old_locus_tag="C8250_036970"
     CDS             complement(41907..42440)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS36940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_036970"
                     /product="hypothetical protein"
                     /protein_id="WP_138356846.1"
                     /transl_table=11
                     /translation="MSPTARPLIELGRPGDEGLPDNAAVIAALSAPAPGPMAQRLLLLH
                     FTGRRTGRAFTIPVGAHTLDEDLVLATSGNWRHNFAGGGDAEITWQGDRRPARLDLVTD
                     PVRIANGYLRLIRLYGPAAQRRLDLTIHPDRPPTTADLRDAVERYGLSLIDVRLSAPRP
                     PAPSHPGAQDAAGT"
     gene            complement(42437..42898)
                     /locus_tag="C8250_RS36945"
                     /old_locus_tag="C8250_036975"
     CDS             complement(42437..42898)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358455.1"
                     /locus_tag="C8250_RS36945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036975"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_187145135.1"
                     /transl_table=11
                     /translation="MVLLQVLSVAVILGTGIVAGVLFAVAISVMPALIAMPADRYITTH
                     RLLGRRYDHIMPYLVMTSVVVDVFAAFRTESTASRPLFAVAGAFMVGVAVVSQTRNVPI
                     NNRVKSQDENNLSPDWQDPRQQWRNWHALRTAFAIVALILTASAVAVLR"
     gene            43147..43404
                     /locus_tag="C8250_RS36950"
                     /old_locus_tag="C8250_036980"
     CDS             43147..43404
                     /NRPS_PKS="Domain: ACP (10-80). E-value: 8.8e-14. Score:
                     43.6. Matches aSDomain: nrpspksdomains_C8250_RS36950_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1129: acyl carrier protein"
                     /gene_functions="biosynthetic-additional (t2pks) ACP
                     (Score: 110.3; E-value: 8.1e-35)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468323.1"
                     /locus_tag="C8250_RS36950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036980"
                     /product="acyl carrier protein"
                     /protein_id="WP_138356845.1"
                     /sec_met_domain="PP-binding (E-value: 2.5e-06, bitscore:
                     26.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDFTLQELTAKLRECAGEPDGVDLDGDVQDTPFMELGYDSLALL
                     QVTGVIKRERRIDLSDDAVVEAETPRILLKMINTSLAQPS"
     aSDomain        43177..43386
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36950_ACP.1"
                     /evalue="8.80E-14"
                     /label="C8250_RS36950_ACP.1"
                     /locus_tag="C8250_RS36950"
                     /protein_end="80"
                     /protein_start="10"
                     /score="43.6"
                     /tool="antismash"
                     /translation="AKLRECAGEPDGVDLDGDVQDTPFMELGYDSLALLQVTGVIKRER
                     RIDLSDDAVVEAETPRILLKMINTS"
     gene            43474..43854
                     /locus_tag="C8250_RS36955"
                     /old_locus_tag="C8250_036985"
     CDS             43474..43854
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358456.1"
                     /locus_tag="C8250_RS36955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036985"
                     /product="SchA/CurD-like domain-containing protein"
                     /protein_id="WP_138356844.1"
                     /transl_table=11
                     /translation="MPYGAIMYRVKPGHEDEIAKIFENFNRVDTADLRSDDGQQTGRIL
                     GTGLFIKDDVMVRVIHYEGDLAAVGKHMATQPGVHAAEARLAPYLQEERDTSSPRAFGE
                     YFRNASMRSLLQLDVETLETKA"
     misc_feature    complement(43486..43497)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            44058..44393
                     /locus_tag="C8250_RS36960"
                     /old_locus_tag="C8250_036990"
     CDS             44058..44393
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1225: Polyketide synthesis cyclase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC
                     C4-C21/C2-C23|C2-C19 (Score: 178.5; E-value: 6.3e-56)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602372.1"
                     /locus_tag="C8250_RS36960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036990"
                     /product="TcmI family type II polyketide cyclase"
                     /protein_id="WP_138356843.1"
                     /transl_table=11
                     /translation="MHRTLIVAKMQPGKADDIAKIFAESDASDLPHMIGVSRRTLFAFH
                     DLYFHLVEADEDITDGLYRARSHPLYDDINRKLAECVSPYDPNWKEPKDAMAVPFYVWT
                     PEQGRIQ"
     misc_feature    44070..44072
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            44390..44818
                     /locus_tag="C8250_RS36965"
                     /old_locus_tag="C8250_036995"
     CDS             44390..44818
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (t2pks) CYC C5-C18
                     (Score: 215.4; E-value: 4.9e-67)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130549.1"
                     /locus_tag="C8250_RS36965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_036995"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_138356842.1"
                     /transl_table=11
                     /translation="MTTQQPVRISANEVASNRKRGGDIRVTLSPVTAGSTSGFGGVMYL
                     DPSEFVTEHYHPYSEEFIHVIAGELEMTLDGEPLKLGPGDSLLVPIGVRHRLVNIGEVQ
                     AHCAFHLSPLAPRPDLGHVDTEKPTNPQAPNPNVGGAP"
     gene            44815..46092
                     /locus_tag="C8250_RS36970"
                     /old_locus_tag="C8250_037000"
     CDS             44815..46092
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (8-397). E-value:
                     1.6e-49. Score: 160.9. Matches aSDomain:
                     nrpspksdomains_C8250_RS36970_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2ks"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) KS (Score:
                     749.2; E-value: 2.6e-228)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358451.1"
                     /locus_tag="C8250_RS36970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037000"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_138356841.1"
                     /sec_met_domain="t2ks (E-value: 6.3e-230, bitscore: 762.3,
                     seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.3e-51, bitscore:
                     173.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRAVVTGIGVLAPGSLGREGFWDQLSAGRTATRRITLFDPAPF
                     RSQVAAEVDFDPAAAGLTPQQIRRMDRAAQFAVVCAREALADSGAELAALPPERIAVSI
                     GSAVGCTMGLEEEYVTLSDGGKNWLVDSSYGVPHLYGYMVPSTLAVEVAHAVGAEGPVS
                     LVSTGCTSGLDSIGHGVQLIEEGSADIVLAGATDAPLSPITAACFDAIKATTPNNADPE
                     HASRPFDRDRDGFVLAEGSAVLILEEKSAAEARGARIYGEFVGFAGRSNAFHMTGLKAE
                     GREMAEAIRAALDQAKLDPTAVGYINAHGSGTKQNDRHETAAFKRSLGDHAYHVPVSSI
                     KSMVGHSLGAIGSIEVAACALALDRQVVPPTANLKNPDAECDLDYVPVTARDHAMDVVL
                     SVGSGFGGFQSAMVLARPGAVPYERS"
     aSDomain        44839..46005
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36970_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.60E-49"
                     /label="C8250_RS36970_PKS_KS.1"
                     /locus_tag="C8250_RS36970"
                     /protein_end="397"
                     /protein_start="8"
                     /score="160.9"
                     /tool="antismash"
                     /translation="GIGVLAPGSLGREGFWDQLSAGRTATRRITLFDPAPFRSQVAAEV
                     DFDPAAAGLTPQQIRRMDRAAQFAVVCAREALADSGAELAALPPERIAVSIGSAVGCTM
                     GLEEEYVTLSDGGKNWLVDSSYGVPHLYGYMVPSTLAVEVAHAVGAEGPVSLVSTGCTS
                     GLDSIGHGVQLIEEGSADIVLAGATDAPLSPITAACFDAIKATTPNNADPEHASRPFDR
                     DRDGFVLAEGSAVLILEEKSAAEARGARIYGEFVGFAGRSNAFHMTGLKAEGREMAEAI
                     RAALDQAKLDPTAVGYINAHGSGTKQNDRHETAAFKRSLGDHAYHVPVSSIKSMVGHSL
                     GAIGSIEVAACALALDRQVVPPTANLKNPDAECDLDYVPVTARDHAMDV"
     gene            46095..47336
                     /locus_tag="C8250_RS36975"
                     /old_locus_tag="C8250_037005"
     CDS             46095..47336
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (55-408). E-value:
                     2.2e-28. Score: 91.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS36975_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T2PKS:
                     t2clf"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_functions="biosynthetic-additional (t2pks) CLF 11|12
                     (Score: 696.8; E-value: 1.6e-212)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948214.1"
                     /locus_tag="C8250_RS36975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037005"
                     /product="ketosynthase chain-length factor"
                     /protein_id="WP_138356840.1"
                     /sec_met_domain="t2clf (E-value: 1.7e-178, bitscore: 592.4,
                     seeds: 26, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-36, bitscore:
                     125.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSATNGSSAAPVITGLGVTAPTGLTADEHWAAVLAGKPAIGRIT
                     RFDPSSYPVQLAGEVADFDTKARVPSRLIHQTDRWTHLGLSAAAEALEDAEVVPAELPE
                     FEMAVVTAASSGGTEFGQHEMENLYQHDPSWVGAYQSIAWFYAASTGQISIRHGMRGPC
                     GVLCCEQAGGLDAIGQSRRLLRGSSRLVVTGGTDASLCPYGLTAQLSTGNLSTVSDPGR
                     AYLPFDTAASGYVPGEGGAMLILERAADAEARGAGGYARVLGYAAGFDPAPGSERPPAL
                     RRTLEAALADAGVTPAGVDVVFADASGVPAQDAAEAAAIRAVFGPGSVPVTAPKTLTGR
                     LYGGGAALDVATAALALRDQVIPHTVGPESPVPGYGLDLVLGEPRAAALRTVLVLARGH
                     GGFNAALVLGRPAS"
     aSDomain        46260..47318
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36975_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.20E-28"
                     /label="C8250_RS36975_PKS_KS.1"
                     /locus_tag="C8250_RS36975"
                     /protein_end="408"
                     /protein_start="55"
                     /score="91.3"
                     /tool="antismash"
                     /translation="LAGEVADFDTKARVPSRLIHQTDRWTHLGLSAAAEALEDAEVVPA
                     ELPEFEMAVVTAASSGGTEFGQHEMENLYQHDPSWVGAYQSIAWFYAASTGQISIRHGM
                     RGPCGVLCCEQAGGLDAIGQSRRLLRGSSRLVVTGGTDASLCPYGLTAQLSTGNLSTVS
                     DPGRAYLPFDTAASGYVPGEGGAMLILERAADAEARGAGGYARVLGYAAGFDPAPGSER
                     PPALRRTLEAALADAGVTPAGVDVVFADASGVPAQDAAEAAAIRAVFGPGSVPVTAPKT
                     LTGRLYGGGAALDVATAALALRDQVIPHTVGPESPVPGYGLDLVLGEPRAAALRTVLVL
                     ARGHGGFNAALVL"
     CDS_motif       46773..46811
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36975_0001"
                     /evalue="9.90E-04"
                     /label="PKSI-KS_m4"
                     /locus_tag="C8250_RS36975"
                     /protein_end="239"
                     /protein_start="226"
                     /score="12.3"
                     /tool="antismash"
                     /translation="FDTAASGYVPGEG"
     CDS_motif       46857..46877
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36975_0002"
                     /evalue="3.00E+01"
                     /label="PKSI-KS_m4"
                     /locus_tag="C8250_RS36975"
                     /protein_end="261"
                     /protein_start="254"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="GAGGYAR"
     gene            47378..47833
                     /locus_tag="C8250_RS36980"
                     /old_locus_tag="C8250_037010"
     CDS             47378..47833
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-145). E-value: 2e-15.
                     Score: 49.4. Matches aSDomain:
                     nrpspksdomains_C8250_RS36980_Polyketide_cyc2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1128: cyclase/dehydrase"
                     /gene_functions="biosynthetic-additional (t2pks) CYC C9-C14
                     (Score: 255.5; E-value: 3.2e-79)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991629.1"
                     /locus_tag="C8250_RS36980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037010"
                     /product="SRPBCC family protein"
                     /protein_id="WP_138356839.1"
                     /transl_table=11
                     /translation="MAGHTDNEIVINAPIDEVWETTNDVVNWPDLFSEYAKAEILEQDG
                     QTVTFRLTMHPDDEGRVWSWVSERTPDPVTRTVRAHRVETGPFEFMNIYWEYTETPEGV
                     RMRWVQDFHMKPQAPADDAGMTEHLNRNTAIQMKLIKDKVEAASLRK"
     aSDomain        47390..47812
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36980_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.00E-15"
                     /label="C8250_RS36980_Polyketide_cyc2.1"
                     /locus_tag="C8250_RS36980"
                     /protein_end="145"
                     /protein_start="4"
                     /score="49.4"
                     /tool="antismash"
                     /translation="TDNEIVINAPIDEVWETTNDVVNWPDLFSEYAKAEILEQDGQTVT
                     FRLTMHPDDEGRVWSWVSERTPDPVTRTVRAHRVETGPFEFMNIYWEYTETPEGVRMRW
                     VQDFHMKPQAPADDAGMTEHLNRNTAIQMKLIKDKVE"
     gene            47861..48322
                     /locus_tag="C8250_RS36985"
                     /old_locus_tag="C8250_037015"
     CDS             47861..48322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358448.1"
                     /locus_tag="C8250_RS36985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037015"
                     /product="DUF1772 domain-containing protein"
                     /protein_id="WP_138356838.1"
                     /transl_table=11
                     /translation="MPALLIPLVLLMNGLAAGCMLGTLLGGWPLLAGLPDDGYVRTHAF
                     FSGRYDPYMPICTLGTLLGDSVLAAGVGDGWARACFTAAALLALCTVVISFAKNVPVNR
                     WIRTVDPDNLPTGFDATERRSQWGLWNKRRSVITMLALLSNCAALATLL"
     gene            48333..49085
                     /locus_tag="C8250_RS36990"
                     /old_locus_tag="C8250_037020"
     CDS             48333..49085
                     /NRPS_PKS="Domain: PKS_KR (10-174). E-value: 2.3e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_C8250_RS36990_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C19
                     (Score: 414.5; E-value: 3.4e-127)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468314.1"
                     /locus_tag="C8250_RS36990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037020"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_138356837.1"
                     /sec_met_domain="adh_short (E-value: 3.6e-32, bitscore:
                     110.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 9.5e-40, bitscore:
                     136.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLELQGKKALVTGGTRGVGRGIVLALARAGVDVITCYLQEGERV
                     ATLERELKEIGGDHHVLRADLSDPAQVASLLEQAGSLYGHLDLVVNNAGTISHIPYAKL
                     PFEEWQRIVATNLTATHLVTQNALPLLGEGSSVVSIGSKGAEAGIPLRAHYTATKSALV
                     GLTRSLAKELGSQGIRINVVALGVIETEALYDLPQEQQDLMVQRYSSKTALGRLGRTDE
                     VAGAILWLASDLSRYVTGATISVDGGIS"
     CDS_motif       48363..48425
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS36990_0001"
                     /evalue="1.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS36990"
                     /protein_end="31"
                     /protein_start="10"
                     /score="11.5"
                     /tool="antismash"
                     /translation="LVTGGTRGVGRGIVLALARAG"
     aSDomain        48363..48854
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS36990_PKS_KR.1"
                     /evalue="2.30E-10"
                     /label="C8250_RS36990_PKS_KR.1"
                     /locus_tag="C8250_RS36990"
                     /protein_end="174"
                     /protein_start="10"
                     /score="32.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGGTRGVGRGIVLALARAGVDVITCYLQEGERVATLERELKEI
                     GGDHHVLRADLSDPAQVASLLEQAGSLYGHLDLVVNNAGTISHIPYAKLPFEEWQRIVA
                     TNLTATHLVTQNALPLLGEGSSVVSIGSKGAEAGIPLRAHYTATKSALVGLTRSLAKEL
                     G"
     gene            49085..49408
                     /locus_tag="C8250_RS36995"
                     /old_locus_tag="C8250_037025"
     CDS             49085..49408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019061794.1"
                     /locus_tag="C8250_RS36995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037025"
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_138356836.1"
                     /transl_table=11
                     /translation="MAGGAFRVMLEMTIKPGLSAEFEQEWRSGTDAVTGHPANIGQWLA
                     RSTADEDTYYIVSDWVDETGFRAFEDGKAHVAHRERLHAYRASATFDTMRVVEHIQGAA
                     HAA"
     gene            49398..49718
                     /locus_tag="C8250_RS37000"
                     /old_locus_tag="C8250_037030"
     CDS             49398..49718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468312.1"
                     /locus_tag="C8250_RS37000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037030"
                     /product="antibiotic biosynthesis monooxygenase family
                     protein"
                     /protein_id="WP_138356835.1"
                     /transl_table=11
                     /translation="MPPEAGEVLVMIHHQARDEAELAAVREAYHVVSRRLADVPGMLAN
                     ELLQSALDPSALTVVSRWADLAAFQSWEEGAGHRADTAPLRPYRDTRLSAPFGIYRVDA
                     AY"
     gene            49730..50467
                     /locus_tag="C8250_RS37005"
                     /old_locus_tag="C8250_037035"
     CDS             49730..50467
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (9-168). E-value: 1.2e-17. Score:
                     56.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS37005_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR C11
                     (Score: 407.3; E-value: 5e-125)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602396.1"
                     /locus_tag="C8250_RS37005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037035"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_138356834.1"
                     /sec_met_domain="adh_short (E-value: 9.2e-35, bitscore:
                     119.2, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-34, bitscore:
                     118.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQGLAGKRVLITGGTRGIGRAAALAFARAGARVVVVSRSAGEDG
                     ESLARELKETGDGHLLLRADVTDAADVRTVAAQVREAVGGLDVLVNNVGVDGQVWFAEL
                     PESEWHRVFDHNVTSAYLMTQAALDLLVDGASVVNIGSSVALRGRVRGVHYTASKAALI
                     GLTRALCKELGPRSIRVNTIAPGLTETEPGAGLPPEAVERIVGMTALGRICTPQDVAGA
                     VLFLAGDTSRYISGATLNVDGGV"
     aSDomain        49757..50233
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS37005_PKS_KR.1"
                     /evalue="1.20E-17"
                     /label="C8250_RS37005_PKS_KR.1"
                     /locus_tag="C8250_RS37005"
                     /protein_end="168"
                     /protein_start="9"
                     /score="56.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLITGGTRGIGRAAALAFARAGARVVVVSRSAGEDGESLARELKE
                     TGDGHLLLRADVTDAADVRTVAAQVREAVGGLDVLVNNVGVDGQVWFAELPESEWHRVF
                     DHNVTSAYLMTQAALDLLVDGASVVNIGSSVALRGRVRGVHYTASKAALIGLTRA"
     CDS_motif       49760..49849
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS37005_0001"
                     /evalue="1.80E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS37005"
                     /protein_end="40"
                     /protein_start="10"
                     /score="27.0"
                     /tool="antismash"
                     /translation="LITGGTRGIGRAAALAFARAGARVVVVSRS"
     CDS_motif       49862..49915
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS37005_0002"
                     /evalue="3.60E-01"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS37005"
                     /protein_end="62"
                     /protein_start="44"
                     /score="3.6"
                     /tool="antismash"
                     /translation="GESLARELKETGDGHLLL"
     gene            50470..51327
                     /locus_tag="C8250_RS37010"
                     /old_locus_tag="C8250_037040"
     CDS             50470..51327
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358432.1"
                     /locus_tag="C8250_RS37010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037040"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_138356833.1"
                     /transl_table=11
                     /translation="MDIGLGLPTTVPDKSGPGLAAWARAAEDSGFTTLGVLDRLVYDNF
                     EPLMSLAVAAAVTTRIKLASTILIAGYRGGAALLAKQTATLDAVSGGRFTLGVAAGGRD
                     DDYKATGADYAGRGARLDELLGELRDIWSGEGPGPVIGPLPAGQGGIPLLVGGHSRTAM
                     RRSARFGTGWIAGGSSATAYGELVRQAQHEWTLAGRTERPRMVSLVYACLGPDAGSTAG
                     RYLRDYYSFIGVKAERAASGVLVDAAQIRDAAQAYAEAGCDELILLPCTADSQQVSLLA
                     KAAL"
     gene            complement(51503..53110)
                     /locus_tag="C8250_RS37015"
                     /old_locus_tag="C8250_037045"
     CDS             complement(51503..53110)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 303.6; E-value: 6.3e-93)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468295.1"
                     /locus_tag="C8250_RS37015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037045"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_138356832.1"
                     /transl_table=11
                     /translation="MYDVNIPVLIVGAGPVGLSTALFSGRHGISTLLLEKRTATSTLPR
                     APGLQSRTLELFRAAGIGKDIRALEMGDSHPFFEGGIIQVDTFADIDNAVVLESPSLDG
                     PTVSPERVMGCGQDRYERVLVDKAREFGADIRFGTKLIEFTQDDEGVTAVAEELETGRR
                     YTIRAGYLVGADGANSHVRTELGVERSGRGTVFDALSIYFKAPELESLIKHRPFILCYA
                     NVNGTLMGLSRLHGCDPFLAAPIYFPDKGEKPEDFTDERCIDIVRTGSGRPDMDVEIVA
                     KVPWQGAQLVAERFRTGRIFLAGDAAHLHPPAGGFGANTGIHDAHNLSWKLAAVIKGWA
                     GDVLLDSYHEERHAVGSAMAEQAMVRNRIRHGYATDEDRATMVDDIIITLGYRYKSEAI
                     THDQTGPVLTPHLELKGEPGTRAPHLWVERNGSKLSTIDLFWDSYVLLTDASGAAWAES
                     AVKAAAELGVPLRAHLVGPGAELTPGEERDWGSVYGVGPGGAVLVRPDAFVAWRSQGPV
                     ADPQQVLTEVLSRAAGLG"
     gene            53322..54341
                     /locus_tag="C8250_RS37020"
                     /old_locus_tag="C8250_037050"
     CDS             53322..54341
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C13O|C17O (Score: 442.2; E-value: 2.3e-135)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468294.1"
                     /locus_tag="C8250_RS37020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037050"
                     /product="methyltransferase"
                     /protein_id="WP_138356831.1"
                     /transl_table=11
                     /translation="MTTTPPDVSTAAGILRLGNAFCDAKALLTAVELDLFTQLQEAPSG
                     GATAEEIKGLLSLHGRGLSDFLDLLVALKVLQRTDGVYRNAPGTAKHLVRTGDAYVGGF
                     LLRSSRNLYPAWGRLEEALRTGKQQSGSHYDEVTQNPAILRQFIGSMDAFTNVLGAQLI
                     EAFDWSGFTSVLDVGGARGNLCSQIVKAQPHLAGHVFDLPEMAPFAKELAEELGIPGKV
                     EFHGGSFFSDPLPQAEIVVMGHVLHDWDPSQRSYLIHKAYDAVLPGGTLLVYDRMLDDE
                     PEHAENLVISLDMLLVTDGGSEYPAAEIVGYAEHAGFAGTEVKLLGDYDTLVVARKAA"
     gene            complement(54422..56539)
                     /locus_tag="C8250_RS37025"
                     /old_locus_tag="C8250_037055"
     CDS             complement(54422..56539)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.4"
                     /locus_tag="C8250_RS37025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037055"
                     /product="MMPL family transporter"
                     /protein_id="WP_138356830.1"
                     /transl_table=11
                     /translation="MTPRRTEASGRRLRWLVPLLLILGWLLVSGATGSFSQKLGDVATN
                     DGAAYLPAKAESVHADQLQSTFSDNKTYPAVVVYERASGVTSADQAAVRSDAAAAGKLA
                     GLRGPVSPVSVSKDGRALQFTVPLVNQAKPVSDAVKVLRANASQHPGLAGHVTGLGGMF
                     ADFAGAFSNIDGQLLLVAVGLVILVLLLVYRSPTLPFLVLLGVMCASGVAGAVVYGLAK
                     HGSITFTGQSQGVLSVLVVGATTDYSLLLIARYQEELRRTQNKYEALGTAWRAILKPVL
                     ASGGTVILGTLCLLFSNLNSNRSMGPVAAIGVAASMLAALTFIPAVLALAGRGVFWPFR
                     PAFGTAERTGSGLWGRVAGLVGRKPRRVWLTAGVVLLLAACFVPQFKASGIAITDSFTK
                     TTDSSTGQKILGAHFAGGSGTPVSIITKAATADQVVAATSKVSGVTSVTRLNKVVNGLA
                     EVDAVLAATPDGPAAVDTVKQIRVAVHAVPDADAKVGGFTAISIDTRAGGIRDLKVVVP
                     LVLVAILIVLALLLRALVAPLLLIGTVVLSYAATMGISALVFNHVFHFANADPSVPLMG
                     FVFLVAFGVDYNIFLMHRVREESLAHGTRAGTLTALQRTGGVITSAGVVLAATFAALAV
                     LPMVSMAEQAFIVAFGVLLDTIVVRSLLVPALALQLDDRTWWPSRRVFGTQIPRSRAGV
                     ADKQPEPEPAS"
     gene            56818..58209
                     /locus_tag="C8250_RS37030"
                     /old_locus_tag="C8250_037060"
     CDS             56818..58209
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (halogenases)
                     flavin-dependent cycline orsellinic halogenase"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000024: Halogenation (76% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_functions="biosynthetic-additional (t2pks) HAL
                     (Score: 654.6; E-value: 1.8e-199)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358435.1"
                     /locus_tag="C8250_RS37030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037060"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_138356829.1"
                     /sec_met_domain="Trp_halogenase (E-value: 1.2e-27,
                     bitscore: 95.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRESTQILVVGGGPAGATAAGLLAKEGFEVTLLERERFPRYHIGE
                     SILPSCRPILELLGVWDKVERHGFQPKGGAYFFWGDEEWEVRFSAMGDDNPSAWQVVRS
                     EFDEILLDHARELGVEVVEGISVKELEFDGDRPVAALWAETKDAASKGRIAFDYIVDAS
                     GRNGVIATKHLKNRKLHEVFRNVAAWTYWKGAKPLPKGPAGAIGVASTAEGWFWVIPLH
                     DGTTSIGLVTGRDRFNAQRAELGSIQAVYDQSVEQSAIIQELIAGAERVADFKVEQDYS
                     YAAESFGGPGFLLSGDAACFLDPLLSTGVHLATYSAMLAAASISSVLRGEVTEEQAWEF
                     YGTVYRHAYERLLVLVSVFYESYRGKDYHFYNAQRLTEQQRDGLNIQDAFDRIITGIAD
                     LEDAQDVYAKVQQHLTGAESGDPIPLNNLNRVHEQKAAPMTEESAVRGLYLSFFPKLGL
                     RRAGE"
     gene            complement(58420..59712)
                     /locus_tag="C8250_RS37035"
                     /old_locus_tag="C8250_037065"
     CDS             complement(58420..59712)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015297 - antiporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132086.1"
                     /locus_tag="C8250_RS37035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037065"
                     /product="cation:proton antiporter"
                     /protein_id="WP_138356828.1"
                     /transl_table=11
                     /translation="MTGSQAATLFLGIAVILLLARLLGAGAKAIGQPPVLGEILGGILL
                     GPTLFNGAVARHLFPASVGPFLSALANLGLILFMFVIGFELEHSLVRGRGRIAAAVSLS
                     SILLPFGLGVVLALHLSHRHPAHSTAGFVLFFGAAMSVTAFPVLARILTDRGMQRTPVG
                     SLALACAAVDDLLAWSLLAVVTTIASGTGQWHTLLAPVYLALMIGVVRPLFRRLFATHS
                     TSGRLSPQVLTPVLIGLMLSCWATEWMGVHFIFGAFLFGLVMPRGGPQVVREGLLNSFE
                     NVGMVFLLPVFFVTAGLKVDLSHLSTRDLGELGLILLVAISGKFIGAFTGAKLQGVSTR
                     HSGVLATLMNTRGLTELVILTVGVQLGVLDKGLYSLMVVMAMVTTFMAGPILRLIYPTE
                     QIERDTLPASLVVVEPNLESEREAERVAHSA"
     misc_feature    complement(59656..59658)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            60172..61380
                     /locus_tag="C8250_RS37040"
                     /old_locus_tag="C8250_037070"
     CDS             60172..61380
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009310916.1"
                     /locus_tag="C8250_RS37040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037070"
                     /product="cytochrome P450"
                     /protein_id="WP_138356827.1"
                     /sec_met_domain="p450 (E-value: 8.2e-28, bitscore: 96.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIPLPDPMNLPAERRCPLDPPEEYAQLRAERPLSRLRLPGGRIG
                     WLVTRYEDVRATLADQRFSPPLIQVTPATDLPLPEEELQVPPGVFSAMDPPEQSRYRRQ
                     VSRYFTRKRTREITPRLTQIINDQLTAMIDHGPPVDLVSWFSQPIPTRVITEMLGIPEP
                     HRAEYQRWILAMLSLKTDADQLREASDGLYGSLGELVRAKRTAPGDDIVSDLLHHGTSP
                     LNDDEVVGISALLLIAGLETTANMLGLGTFALLQNPDQAAKLRANEDLLDTAVEELLRY
                     LTIVQFGLTRTAREDTEIAGQLIRAGETVVTSLAAGNRDPGVYPDPDQLDVSRQGAPHM
                     AFGFGVHQCLGAHLARVEMKIAFEALLRRLPGLRLAVPAEEVPTGVDKVFYGVHSLPVT
                     WDT"
     gene            complement(61552..62571)
                     /locus_tag="C8250_RS37045"
                     /old_locus_tag="C8250_037075"
     CDS             complement(61552..62571)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     (Score: 218.8; E-value: 2.5e-67)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="C8250_RS37045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037075"
                     /product="methyltransferase"
                     /protein_id="WP_187145136.1"
                     /transl_table=11
                     /translation="MSSQISGQPATAAEYLPLSFGFALHQIGAAVSSLGVLDALADGPR
                     TAAQLVEVTDAHAGSLRRLLYAATKAKLLTVDSEGYHLAPLSAFFGPLSDYHAAPEIWA
                     AWGAFEESIRTGVDAFQIANGAPLFDYIKTNPKLAATFHAAMSAGSDAQVPAIVEHFDF
                     SRFKTIVDCGGGKGTHLTAILAANPHLQGTIFDTANGVVEAAAVIEDAGVGDRCEVVVG
                     SFFDSVPEGADLYVLKNILHDWNDEESVQILSNIRKAMAPGGRVVVLSSVLSEGEDEDP
                     GDALGGAISDIEMLVMTTGLERSQSEYAQLFTDAGLKLSTATALPCPWLYYALEATAS"
     gene            complement(62622..63632)
                     /locus_tag="C8250_RS37050"
                     /old_locus_tag="C8250_037080"
     CDS             complement(62622..63632)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET
                     C13O|C17O (Score: 402.7; E-value: 2.4e-123)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468294.1"
                     /locus_tag="C8250_RS37050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037080"
                     /product="methyltransferase"
                     /protein_id="WP_138356825.1"
                     /transl_table=11
                     /translation="MTSTGADPGTAAGIIRLGTAFCDAKALLTAVRLDLFTVLAQNPAT
                     AGELRTLLRLHGRGLPEFLALLAARGLLRRDVDGRYHNAEGADRHLVAGRPGAVTGFLI
                     GADINLYDVYGRLGEALRTGKPQADGDFAGMLQDPVAVDRFARMMDGLTEGFGAKLLDA
                     LDGTRFRTVLDVGGCRGHLTGQLLAARDDLVGHVFDLPQMEPVFDEHMAELGLTERAHF
                     HAGDFFRDPLPPADVIIFGHNLSDWDPDQRRLLLTKAYTALSPGGTVLVYDRMLGERRD
                     DTENLVASLNMLLVTEGGREYTVAELGAQARATGFSSITHRPLADHDTLVSCRKD"
     gene            63883..65076
                     /locus_tag="C8250_RS37055"
                     /old_locus_tag="C8250_037085"
     CDS             63883..65076
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602378.1"
                     /locus_tag="C8250_RS37055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037085"
                     /product="cytochrome P450"
                     /protein_id="WP_138356824.1"
                     /sec_met_domain="p450 (E-value: 6.6e-23, bitscore: 80.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESCPVGYPIPWAPTPDIPEEWKALRERSLVEITLPSGEPAVLV
                     TRYKDVRRLFADERLSRNTFGRASRVSASNDLFGDPNVDNDPPRYLEERSVVMRAFSAR
                     RIEALRVFVKKVVIDLLDEMEAGPQPAELMEAFAYPLPILVICQMLGVPAEDRTKFRRL
                     IDGYLSVTRLPEDEVEECRKQYWDYLTELIDSKRAQPGDDLISELIEISREDPGKLTDY
                     QLQNWVKTLLIAGYVTTASQLGTSMAVLLHRPEVADDLKADLSLVPSAVEELLRYQIMG
                     TSLGTLRYAVEDIELSDGAVVPKGSSVLLSQESNHDEEVFEDPLTLDIRREDNHHLTFG
                     AGIHFCAGAALARMELQEATEGLLQRFPGLKLAIPGDELVRPEGGFLAGYTNVPVTW"
     gene            65082..65342
                     /locus_tag="C8250_RS37060"
                     /old_locus_tag="C8250_037090"
     CDS             65082..65342
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024851.4"
                     /locus_tag="C8250_RS37060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037090"
                     /product="ferredoxin"
                     /protein_id="WP_244809609.1"
                     /transl_table=11
                     /translation="MGSLRVSANQDTCVTSSLCVYRVPQVFDQDEDGLVLVVNAEPPQE
                     LREDLLHAQRSCPTRSIRIEEPAVGAGADGADSGSGQAATG"
     misc_feature    65507..65521
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.0"
                     /tool="antismash"
     gene            65554..66657
                     /locus_tag="C8250_RS37065"
                     /old_locus_tag="C8250_037095"
     CDS             65554..66657
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_functions="biosynthetic-additional (t2pks) GT (Score:
                     375.4; E-value: 1e-114)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468280.1"
                     /locus_tag="C8250_RS37065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037095"
                     /product="nucleotide disphospho-sugar-binding
                     domain-containing protein"
                     /protein_id="WP_343240943.1"
                     /sec_met_domain="MGT (E-value: 2.7e-115, bitscore: 384.7,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPLAWACRVAGHDVLMASQPALTYAVLRTGLPAAPVGQNVDAEA
                     VFRNIVLTPPSAQPGSGGGPRVLDLLSNLAQAMVDDLVELGREWRADLVVFDPTAFAGP
                     LAAAKLGIPAVRHLYGTDLMSVVGRFVTGALGPLSEKLGLDGVDPFGVGTVDPCPGGLQ
                     VPTASRRLPMRYIPYNGPGLAPPRLPERSGRPRVCISWGTTMGRLDPGLFLAGDVARAI
                     DGLDVDVVVASTRGQRELLGTLPDGVDVVESAPLHLLLPQCDLMVAHGGAGTLLTALSQ
                     GLPQLLVPRLPDHVRHSGRLAEAGAGVVLPAPVDGPEPIRERLAELLAGPGYRESAQRL
                     QEEMRRQPAPAQVVGELESIAAGAPAT"
     misc_feature    66689..66704
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.84"
                     /tool="antismash"
     gene            66800..68152
                     /locus_tag="C8250_RS37070"
                     /old_locus_tag="C8250_037100"
     CDS             66800..68152
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_functions="biosynthetic-additional (t2pks) OXY
                     (Score: 22.9; E-value: 9.1e-08)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602362.1"
                     /locus_tag="C8250_RS37070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037100"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_138356822.1"
                     /transl_table=11
                     /translation="MSAPTSTLHVVIIGAGTGGLCLAHGLKRAGVSVAVYERDATRADG
                     LQGYRVGINPDGTRALRDCLPPDLYATFLATCARPPEYVNFLTEGRKEVLSLDGFKSDD
                     AVDSEKSVSRMTLRQVLLTGLQDIVHFGKTFKRYRTNDDGSVTAFFEDGSSVDGTVLVA
                     ADGSNSRVRRQYLPHARLEDCGPIGITGKVPVTDETVALLTPKMRRGISMIYAPKGVFC
                     IYHAMEFPWDADGAPKDGIGSSDAELLGQWPGLTFDNTRDYINWGYVTRAKRLPDDTLK
                     MKGPDLYRLVNERTTDWHPDLRKLFELADPNSCFPIKIRTAVPIPQWETTHVTLIGDAI
                     HTMTPGRGVGANTALRDARLLCRMLVAAHEGREPLLAAIRDYETKMIEYGFDAVKESRK
                     SGGGTGPDQPFVGRILLAALRTTMRVVNHLPALKRRLADSDRSYRGHGRED"
     gene            68254..68922
                     /locus_tag="C8250_RS37075"
                     /old_locus_tag="C8250_037105"
     CDS             68254..68922
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602377.1"
                     /locus_tag="C8250_RS37075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037105"
                     /product="TenA family transcriptional regulator"
                     /protein_id="WP_138356821.1"
                     /transl_table=11
                     /translation="MLYEELAEICGPVLRKVLDHPFWAGLRDGSLPVGSLARFVEQDAG
                     FLLPAYARALARCAAVAPDEADTFLFGQSVTGTLDARDELRSSYLSLAGELGLPELDAR
                     PAIHAATHAHTSFFTAASASSFHAGVGALLPMVWFNAEVSDNLLRNAVPGTRYVPWIRS
                     YHPGESYQYAVQAFRDMADRVGESSSAAQRRVIIDQFSLSIRYEWAFAECCAGQPSWPV
                     "
     gene            68967..70178
                     /locus_tag="C8250_RS37080"
                     /old_locus_tag="C8250_037110"
     CDS             68967..70178
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="C8250_RS37080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037110"
                     /product="cytochrome P450"
                     /protein_id="WP_187145137.1"
                     /sec_met_domain="p450 (E-value: 2.3e-20, bitscore: 71.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATNDLDLMDPKVFNNGIPYDYFRQLRHSEGLPLGKDTDGERFWY
                     LTRHRDVSEVSRDTKRFSSSPTTMTSIRKVDPSPPIITFLDSPDHTRLRKLTFKAFAPA
                     RLAALEGPIRRIVDSLLAEVAEKGEFDLAEDIALRLPFEVLLELLDIPAGDRAMMLGWA
                     GQTVNLGDAEYEAAAAEGGLDSFQKIYEYLLDFARYRAKNLTDDCFSVLLSARFNGERL
                     GLPDRLTPDEVGLFASTLITAGSETTYCSVTGGVLALMENPDQLTALRGDRTLMPGAAN
                     EVLRWVTPVTHFARRALVDTEIAGQPIGAGERVVMWYTSANRDEEVFTDPDRFDIARTP
                     NPHLAFGGGGPHVCIGNALATMELRQFLEGIVDLLSRLEIAGTPVRPETNFMNSIKYLP
                     MRFR"
     misc_feature    69771..69773
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            70197..70898
                     /locus_tag="C8250_RS37085"
                     /old_locus_tag="C8250_037115"
     CDS             70197..70898
                     /NRPS_PKS="Domain: PKS_KR (11-177). E-value: 2.1e-08.
                     Score: 26.2. Matches aSDomain:
                     nrpspksdomains_C8250_RS37085_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     102.9; E-value: 5.1e-32)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358440.1"
                     /locus_tag="C8250_RS37085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037115"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_138356819.1"
                     /transl_table=11
                     /translation="MTSENAATPPRTALITGANRGIGRAVAAELHHRELQVVVAARLAG
                     EGRGAAAGIGPGVRSCVLDVTDPDSVKLAGSEAGPVDVLVCNAGVLLDARTDPLSVPLE
                     LVERTLRVNLLGTWRVLQEFVPPMVQRGWGRVVIISSGTTADFGGRLFAGTPGYSLSKS
                     ALNGLTTMLAAQTAGTGVLVNAVNPGRVRTRMMPTQEQLPEAAARFIAEVATLPDDGPT
                     GHFLTEKRGSG"
     aSDomain        70230..70727
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS37085_PKS_KR.1"
                     /evalue="2.10E-08"
                     /label="C8250_RS37085_PKS_KR.1"
                     /locus_tag="C8250_RS37085"
                     /protein_end="177"
                     /protein_start="11"
                     /score="26.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALITGANRGIGRAVAAELHHRELQVVVAARLAGEGRGAAAGIGP
                     GVRSCVLDVTDPDSVKLAGSEAGPVDVLVCNAGVLLDARTDPLSVPLELVERTLRVNLL
                     GTWRVLQEFVPPMVQRGWGRVVIISSGTTADFGGRLFAGTPGYSLSKSALNGLTTMLAA
                     QTA"
     CDS_motif       70236..70286
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS37085_0001"
                     /evalue="1.30E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS37085"
                     /protein_end="30"
                     /protein_start="13"
                     /score="14.6"
                     /tool="antismash"
                     /translation="LITGANRGIGRAVAAEL"
     gene            70929..71699
                     /locus_tag="C8250_RS37090"
                     /old_locus_tag="C8250_037120"
     CDS             70929..71699
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     154.9; E-value: 7.2e-48)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142082.1"
                     /locus_tag="C8250_RS37090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037120"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_138356818.1"
                     /sec_met_domain="adh_short_C2 (E-value: 6.1e-29, bitscore:
                     100.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFDLTGKTAVVTGAGSGIGLASVQALASAGAQVLGGSRTISPEL
                     LDATPHVFEVDLLTEAGPTALLEHALGTFGGVDILVNNVGGGVKLATGFLDIEDETWRH
                     TFELNVFSMIRTTRAALPSLVERRGAIINIGSMNASMADPALGHYSAAKAALANISKSL
                     SLEFSSQGVTVNTISPGPVRTRLWTNPEIARRLGITTEEFLETVPKMAGLSTGKMIEPD
                     EIGALVLLLASGKVPSITGSDYFIDGGMSRAAVR"
     gene            complement(71776..72471)
                     /locus_tag="C8250_RS37095"
                     /old_locus_tag="C8250_037125"
     CDS             complement(71776..72471)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (t2pks) MET C9O
                     (Score: 222.3; E-value: 1.2e-68)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="C8250_RS37095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037125"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_138356817.1"
                     /transl_table=11
                     /translation="MTSDTPASAPESAELDPRIVHAQQVYSRSRLGIYDKWVLGVFCRV
                     VWRCPAGVMRRLYNSSAGNRHLDIGPGTGYFVDKCRFPTKTPELTLLDLNSECLDMSAG
                     RLARYRPAICQANLMEPLPLPSRHFDSAAMNLVFHTIPGGWDTKGIILKHVAETLRPGG
                     VLFGTTVLAEGVPMNRLTSKMVLEQHRRGNFQNQGDDPAGLERQLAKYFPEYRVTIRGA
                     VAIFTATAG"
     gene            complement(72489..73298)
                     /locus_tag="C8250_RS37100"
                     /old_locus_tag="C8250_037130"
     CDS             complement(72489..73298)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="C8250_RS37100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037130"
                     /product="ABC transporter permease"
                     /protein_id="WP_138356816.1"
                     /transl_table=11
                     /translation="MTTAVATSQSRAGLLTSTGLLAKRTTLTFWRRTELIVLSVLQMTS
                     IMLTFRYIFGGAIGTSQGLDYVDFSVPGFITAGVLFQTLGTAIGMAEDVEGGFIDRLRS
                     MPFPSSAVLTGRVLADTGILAFVLAITTGVGFAVGFRLHASVLSGLAAFALCLLFGVAF
                     SWVFIAVGLFTGNVKSAQGVSMVVFIVTFASSAYVPVGTMPGWLQAFAENQPVTVMADA
                     VRALTLGSHAHALLGHDAGYFVSRSLIWTAGITVVFAALGSARFRRR"
     gene            complement(73324..74328)
                     /locus_tag="C8250_RS37105"
                     /old_locus_tag="C8250_037135"
     CDS             complement(73324..74328)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089664.1"
                     /locus_tag="C8250_RS37105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037135"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_138356815.1"
                     /transl_table=11
                     /translation="MALTIEARGLVKRFGKKTALNGLDLEVESGRVVAVLGPNGAGKTT
                     FVRAVATLLYPDEGELRVVGHDTRREPEAVRRAIGLAGQFAAVDQAMTGRENLELVARL
                     FGQRAKQARANATAILELFDLTDDADRLVRTYSGGMRRKLDLGASLVSAPRLLLLDEPT
                     TGLDPRSRLDLWDAIDALLEQGTDVLLTTQYLDEADRLASHIVIIDEGRTVASGTPAEL
                     KSRIGGKVFEVHVHDRADLPKVAAALARENGAEPQVDEATRCVSVAAGPGNDDTAQWLI
                     AGLRSIEGTAVDLADISVREPSLDEVFLALTDQRPEEEVGANKQHALSAAESV"
     misc_feature    complement(74313..74333)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.08"
                     /tool="antismash"
     gene            complement(74462..76318)
                     /gene="asnB"
                     /locus_tag="C8250_RS37110"
                     /old_locus_tag="C8250_037140"
     CDS             complement(74462..76318)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_functions="biosynthetic-additional (t2pks) AMID
                     (Score: 842.0; E-value: 5.3e-256)"
                     /gene_functions="biosynthetic-additional (t2pks) AMID
                     ELQ83270.1_Oxytetracycline_malonamyl-CoA (Score: 610.0;
                     E-value: 0)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010359672.1"
                     /locus_tag="C8250_RS37110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037140"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_138356814.1"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-43, bitscore:
                     146.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-82, bitscore:
                     277.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGIAGWVDFGQDLSQKRSVLQAMTDAVAKRGVDDQGLWVSRHAA
                     LGHTRTAIIDLADGVQPLTVEEDGRPVAVIVYNGEVYNYKQLRTELQGRGHQFRTRSDT
                     EVVLRSYLEWGPDCAKRLEGIFAFAIWDLRREELLLVRDRFGVKPLFYHRLPEGVLFGS
                     EPKSLLANPLIRPVVDADGLREMFAVAKKPGQAVFRDMRELLPGHTLTIGSAGVVDRTY
                     WELEARPHTDTLQETITNVRSLLEDIVLRELVADVPLCTALSGGLDSSSLTAIAAQWRW
                     KLDGARLRTFVTTFDDYAEKFQADDVRFSPDEPFAIEVAEHLSSDHVNIRLSSHDLMDP
                     KTRLMALLAQDAPSTLGDMDTSNYLTSREIRTHSTVALVGEVADEIFGGYNWMFNPETV
                     GADAFPWVAHEALQPSSMKGQGRGLFDDGLLQKLDMRRYYTDSFHEAAAEAPHQEGESP
                     EEYRMREIGYLTLTRWMPMLLDRSDRLSMAHGLELRVPYCDHRLVEYLYNTPWSFKTFD
                     GREKSILRAAVRDLLPASVLERKKSPWPVTQDPAYTAMLHEELTALISDPNSPILPYLD
                     NKAVEHTLRNPGAANDWPSRMHIETALQFNSWLSHYNVELVV"
     gene            76515..77579
                     /locus_tag="C8250_RS37115"
                     /old_locus_tag="C8250_037145"
     CDS             76515..77579
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_functions="biosynthetic-additional (t2pks) MET C11O
                     (Score: 463.7; E-value: 7.2e-142)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.4"
                     /locus_tag="C8250_RS37115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037145"
                     /product="methyltransferase"
                     /protein_id="WP_138356813.1"
                     /transl_table=11
                     /translation="MTAQDSASGAQGTAGWFDASLPPQQQVLGFLYAKWVIGALRALVE
                     LKVPDALADGPRTVAQISETTGTDADALYRVLRAVAAAGVLEERTDGSFVLTPVSAGLV
                     SDATDGIRDMFLFASDPTLWRPYENVAHSVRTGEAAFNNVFGMSYYEYTKANPASGAVL
                     DRAMKQNHYPGTDRIFAEFDFGRFPRIADVGGGRGQFLAEVLRRHAGVTGVLADQAHTV
                     ADAKETFADDGLADRVEIVPTDFFVEVPAGCDAYFIKHTLHNWADDKAELILRRIREAI
                     GGNGEARLLIVENLLRGPGEWDIGKLIDVESLAVLGGRERSREEWNHLTAAAGFAPANE
                     PVPGDIALLEYRPV"
     gene            77698..78450
                     /locus_tag="C8250_RS37120"
                     /old_locus_tag="C8250_037150"
     CDS             77698..78450
                     /NRPS_PKS="Domain: PKS_KR (9-174). E-value: 1.3e-13. Score:
                     43.2. Matches aSDomain:
                     nrpspksdomains_C8250_RS37120_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_functions="biosynthetic-additional (t2pks) KR (Score:
                     160.7; E-value: 1.2e-49)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602399.1"
                     /locus_tag="C8250_RS37120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037150"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_138356812.1"
                     /transl_table=11
                     /translation="MDLGLTDKRVLVTGATRGIGRATARVFAAEGARVAVTYHSNEVAA
                     KELVQELGGADRACAVPYDLAVPESIEQAVRSIEDRWGGVDVVVANAQTWEWINPQEMP
                     QYQDFPMDFWLSKYRENVEGHLWTVRQALGGMRERGWGRVVLLSSVTATHGNPGSEIYS
                     AAKAALHGFVRGLMWTGDGVLANVVAPGGTLTESLEAVDPALLEVAVRETPSGRLSTAD
                     DVARLIVFLSSEANGNVNGQVIHPAGGR"
     aSDomain        77725..78219
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS37120_PKS_KR.1"
                     /evalue="1.30E-13"
                     /label="C8250_RS37120_PKS_KR.1"
                     /locus_tag="C8250_RS37120"
                     /protein_end="174"
                     /protein_start="9"
                     /score="43.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VLVTGATRGIGRATARVFAAEGARVAVTYHSNEVAAKELVQELGG
                     ADRACAVPYDLAVPESIEQAVRSIEDRWGGVDVVVANAQTWEWINPQEMPQYQDFPMDF
                     WLSKYRENVEGHLWTVRQALGGMRERGWGRVVLLSSVTATHGNPGSEIYSAAKAALHGF
                     VR"
     CDS_motif       77728..77796
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS37120_0001"
                     /evalue="2.50E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS37120"
                     /protein_end="33"
                     /protein_start="10"
                     /score="20.1"
                     /tool="antismash"
                     /translation="LVTGATRGIGRATARVFAAEGAR"
     CDS_motif       78130..78213
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS37120_0002"
                     /evalue="1.60E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="C8250_RS37120"
                     /protein_end="172"
                     /protein_start="144"
                     /score="14.2"
                     /tool="antismash"
                     /translation="VLLSSVTATHGNPGSEIYSAAKAALHGF"
     gene            78452..79114
                     /locus_tag="C8250_RS37125"
                     /old_locus_tag="C8250_037155"
     CDS             78452..79114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468282.1"
                     /locus_tag="C8250_RS37125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037155"
                     /product="TenA family transcriptional regulator"
                     /protein_id="WP_138356811.1"
                     /transl_table=11
                     /translation="MLRDELSAIAKPVLAAVLEHPFWDGLRKGTLPADSLWYFAEQDAR
                     YAVPAYARALARTAAIADQDAHSALMSGAASVTLDAVGRMDGELAALAAELGRTVRTVA
                     VSPATHAHTCFMLAAPAVSFGAAFGGLLPMTWFHQAVSRDLRERCVPGSRYEAWIDQYC
                     PESGFHDYVEAYLSMIDEFGEQCSPTDRATLAEHFLFGARHELAFADSAFRLQAWSV"
     misc_feature    complement(79176..79190)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            79308..80807
                     /locus_tag="C8250_RS37130"
                     /old_locus_tag="C8250_037160"
     CDS             79308..80807
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS37130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_037160"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_187145138.1"
                     /transl_table=11
                     /translation="MAGMTLGVSGTSAAADSQGGQRYYLDCAAGNDAAAGTAQGSAWRT
                     LDHVNALVFHPGDSILLRSGTTCQGTFSPKGSGTEDRPIVAGSYGSGARPVIVADGARA
                     VVFLHNVQYWELRNLDISDRAAGNGTSRTGIYVLLEDYGTGHHYVIDGVNVHHVVGIDA
                     TGPANEDSAGILFKATGSTVATGFDGIQVTGNTVSGVDGYGIATSSQWSLRPLLTSGTN
                     TFVPISHVRIAGNRLSDLGGDGIVVQNGIDPLVEGNVIDGFGKRATAFHAGIWSWNSDR
                     PVMQYNDVSHGSSSPPAFAFDVDIAAAGVLYQYNYSHENAGFMLLCTNPGEKSAGATIR
                     YNVSENDRGALFGTTELPLVTNGCGSVQPDVRFYNNVIHTKYASGLIGNFGETAVAYSN
                     NIFSGKPGGSTIGDPMASFDHNLYFNVTSAPTVDAHAVAADPAFVRPGAGPLGYLLKCG
                     SPAIGAGVLIAGDTGHDFLGFPVPHDAPPNIGPHQSPCVHV"
     gene            80897..81754
                     /locus_tag="C8250_RS37135"
                     /old_locus_tag="C8250_037165"
     CDS             80897..81754
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012517.4"
                     /locus_tag="C8250_RS37135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_037165"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_138356809.1"
                     /transl_table=11
                     /translation="MDIGVCLPTAVHGADSSQLIEFARRADRLGFHSLTVTDRVVYDNY
                     EGIVTLAAAAAVTERINLVTAILLAATRPSPVELAKQLASLDRLSDGRLILGLSAGMRE
                     DDYVATGTDYATRGRRLDAMIEEMREVWQGRGPVPGVGPRPTNGDIPFWGGGHSPGGLR
                     RSAKYGIGWISPGGPPHKFGELVANFAKLWAEEGRTGTPRMAANCYVSLGPGGKELATE
                     HMLSYYAYMGKVAEHLAAGAITEEDRLRQVVDAYAANGCDELLLLSVTADPDHLDRIAD
                     VVLR"
ORIGIN
        1 tggtcggcaa ctggcggcgc gagaccgcca ggttcgcccc gatgctgcgg gtctacgtcc
       61 accacggggc cggccggctg tccggcgccg agttgcggga agcggtcgcc ggcgccgatc
      121 tggtgatcac cacgtacggg ctggtgcagc gcgacaccga ggcgctcacg cagaccgtct
      181 ggcggcgcgt catcatcgat gaggcgcagc acatcaagaa ctccgccacc cgccagtacc
      241 gggcggtccg cgaactgacc gccgaccacc gcatcgcact caccggcact cccgtcgaga
      301 accggctggc cgaactgcac gccatcctgg acttcgccaa ccccggcctg ttcggttcgg
      361 cgatccgctt caaggagcgg tacgccgttc ccatcgagcg cgacggcagc gaggccgccg
      421 cgcaggcgct gcaacagcgc acccggccgt tcgtcctgcg gcggctgaag ggcgatccgg
      481 ccatctcgcg ggacctgccc gccaagcagg agatgacggt gctgtgcaat ctcacagccg
      541 aacaggcggc gctgtaccag gcggtcgtca ccgacctcct ggagcagatc aaggagagcc
      601 gcggcatcga gcgcaagggt ctggtgctgg cgtcgctcgg caagctcaag caggtgtgca
      661 accaccccgc gcagttcgcg cacgacggct cgccgctggc ggggcgctcg gggaaggtcg
      721 cccggctgga ggagacgctg gaggaggcgc tcgccgaggg cgacaagacg ctgtgcttca
      781 cgcagttcgc cgagttcggt tcgctgctgc aggggcacct ggcccagcgg ctggacaccg
      841 acgtcctgtt cctgcacggc ggggtgcccc agcgggcccg cgacgagatg atcgagcgct
      901 tccaggaccc ggacggcccc tcggtgttcc tgctctccct caaggccggc ggcaccggcc
      961 tcaatctgac cgccgccaat caggtcatcc atgtcgaccg gtggtggaac ccggcggtcg
     1021 aggagcaggc caccgaccgg gcgttccgga tcggacagcg ccgtgacgtc caggtccgta
     1081 agttcgtgtg cgtgggcacc gtggaggaac gcatcgacgc gatgatcgag gcgaagcgga
     1141 ccgtggccag ggctgccgtc ggatccggcg agaactggct gacggagctg tcgaccgacg
     1201 cgctgtacga cctggtcggt ctcggcgccg acgcggtgag cgaatgacgg ggcggccggg
     1261 gctgcccggc agggcgcgct cttggtccca gcggttcgcc gaccggctgg aggccatcgg
     1321 cgcgaccgtg ccgccgggcc cgcccgccgc cggggtgacc gggctggagg tcgaggccgg
     1381 cgccgtgacg gcccgggtca gggaggggca ggcgcgctac gacgtgcgga tcgggctggc
     1441 ggagttcacc ccggcgcagt ggacccgcgc cgtacgggcc gtcggcgccg accccgactg
     1501 ccgggcgcgg ctgctcgaca acgaactggc tcccgacgcg gaggacctgt tcgccagggc
     1561 cggcctgcgg ctcttcccgg cgcgcacccc ggatctcgcg atggagtgct cgtgccccga
     1621 ctgggcgctg ccctgcgccc atctcagcgc ggtgctgcgg agcctggccg acgcgttcga
     1681 cgccgatccg tatctcgtcc tgacctggcg cgggcgcacc cgcgaggagc tgctgaagga
     1741 gctgccgccc gccgtgccgc ggcgcgagcc ggcggactcg gcgctgttgc tgctcggccg
     1801 gccggcgatc accgtccgcg gccgcggtct gaccgaggtg ctggggccgg cctacgaggc
     1861 gttcaccggc tggtgacccg gtcctgaggc acgtcgagca ggcgggccat cgccaccggc
     1921 ccgccgggat cggatctccg atgtcccgct gcgactgcgg ctattggtcg ggatccgagt
     1981 gcctgttcta ggcttggatc atggaattcg agatcgtcag ggaaagcatc accattccgt
     2041 ccggcgacgg ctccatgggc gcccacctgg tccggccgca ggcccccggc cgttacccgg
     2101 gtgtggtcgt cggcttcgag atcttcgggc tgaccgcgca catccgtgac gtcgcggagc
     2161 ggatcgcccg tctcggctac accgtcatcg ttcccgactt ctaccaccgg gccggaacgg
     2221 gcatcgactt caccgacgac ccggacggcc gcgtcaaggg actcgaactc agcggcgggc
     2281 tcacccgcga gggggccgtc gaggacatcc gcgcggccgt ggaccatctg cggggcgcgg
     2341 agctcgctgc cccgtccgtc gggatgatcg gcttcagctt cggcggccat ctcgcctatc
     2401 tggccgccac tcagttcgat ctcgcggcga ccgcggtctt ctacgccggc tggctcgcca
     2461 gctccgacat cggactcggc cgcccggggc cgaccctcac gctcaccgag ggcatcgccg
     2521 agcacggcgg ccggctggcc ttcttcgtcg gtgacgagga ccacgccgtc cccgccgcgg
     2581 accgtgccgc gatcggcgcc cggctggcgg aggccggcgt gcggcacgag atcatcgtct
     2641 accccgggat cccgcacggg ttcttctgcg acgtccgtga ctcgtaccgc aaggaggccg
     2701 cggacgacgc ctggatccgc gtccaggagc tcttcgcggc ggaactcccg cggcccgcgt
     2761 agcgcgtggc gcttcgtcca gccggccggg cttcccggcc ggctggggag cgctctccct
     2821 gaacgtccga tgtgtcatca gggctgtcga tgcgcgtaac gaactcccct cggttcatcg
     2881 aacaatcggg ctcaactggt ccgatctatt gacgcaattg gaaggtttct ttaccgtcct
     2941 gtgcggtaga ggttcggccc atccgccgca gttcgactgt gacttgtcat gccttgatca
     3001 agtactgggc cgagcacgga ttccgtagga ggacgcgcaa tgccgaggcc ccccacccct
     3061 cgccgattca ccccgagagc cctgatcgcc accggggcgg tcacggccac cgccgccgga
     3121 ctgctcgtgg ccgtcgccgg aacaggcagt gccgctcccg tgctgctcag ccagggcaag
     3181 cccgccacct cgtcgtccga cggcggcacc ggatacgccg cgaagctcgc gttcgacggc
     3241 gacaccgcga cccgctgggc gagcgtcaga aacgtcgacc cccagtggat cagggtcgat
     3301 ctgggcacag cggccaccat cagctcggtc aagctggtct gggacctgtc ctgcgccacg
     3361 gcgtacaagg tcgagttctc gaccgacggc agcacctgga agagcgtcta ctccaccacc
     3421 acgggcgacg gcggcaccga cgacctcgcg gtcagtggaa ccgcccgcta cgtccgcacc
     3481 accggcaccg cccgctgccg gcccaccatg ggctactcgc tgcaggagtt ccaggtcttc
     3541 ggcggcggca gcgccgacac ccagcccccc accaccccgg gcaacctgca ctccaccggc
     3601 tcgacgccga ccagtgccgc gctcgcctgg aacgcctcga cggacgacgc gggcgtcgcc
     3661 gcgtacgaca tctacaacga cggcaacaag atcgcggagg cggccggcac cgccaccacc
     3721 aagaacgtca ccgggctgac ccccaacacc gcgtaccgct tcaccgtctt cgcacgggac
     3781 gcggcgggca acgtctcccc ggccagcaac ctggccaccg tcaccactcc gcccagctct
     3841 gacacccggc cgcccaccgc gcccggcggg ctggccgtca ccgggacgac ctccggcagc
     3901 gcctcgctca agtggacggc cgcgaccgac gacacgggcg tgaccgggta cgacgtctac
     3961 aacggcacgg acgtcatcct ccccgacgtc accggcacca cggccaccgt ctccggactc
     4021 gccgccgaca cctcgtacac cttcaccgtc aaggccaagg acgcggcggg caacgtctcg
     4081 ccggccagca accaggtcac ggcgaagacc ctgcccgaca gcggcagcga caagaccccc
     4141 tccagcatca agaccgtctc caccggctgg acgatcccct ggggcatgag ctggctgccc
     4201 gacggctccg cgctcatcac cgagcgcgac tcgttcaagg tcttcaagct cacccaggcc
     4261 ggtgcgcgga cccagatcgg caccgtaccg aacgcggtca ccaccgacgg tgagggcggc
     4321 ctcctcggta tcgcggtctc gcccaactgg agcagcgacc actacgtcta catcatgcac
     4381 accgcctcgg agggcaaccg gatcgtccgg atgacctacg acggctcgac gctgagcggc
     4441 tacacccagc tcgtcggcgg catcaagaag agcaagtacc acaacggcgg gcgcctcaag
     4501 ttcggccccg acggctacct ctacgccacc acgggcgagg cccagacccc cgacctcgcg
     4561 caggacaaga actccctcaa cggcaagatc ctgcggatga ccaccgcggg caaggccgcc
     4621 ccgggcaacc cgttcgggac gctcatctac tcctacggcc accgcaaccc gcagggcatc
     4681 acctgggacc cgcagggccg gctgtgggag gccgagttcg gcaactccaa gtacgacgaa
     4741 ctgaatctga tcacgccggg cgccaactac ggctggccca cctgcgaggg caagtgctcc
     4801 acctccggca tgaccaaccc gaaggcgcag tgggcggtcg cccaggcgtc gcccagtgac
     4861 atcgcctact ccgacggcgc catctacatg gcggcgctga agggccagcg gctgtggcgc
     4921 atcccggtca gcgggaccac cgcgggcact ccggcggcgt actacgtcaa ccagtacggc
     4981 cggctgcgga ccgtcgagaa gatccccggc aagagcgcgc tgtggctctc cacgaccaac
     5041 tgcgacaaca acggcaacgc cgccgacggc gcggacaagg tcttccagat cgagctgaag
     5101 tagcagaacc ggaaccgggg ccgtgaggcc accggtcgca gaccgccggg cggggagcag
     5161 ggggccccgc ccggctttgc gtttccgcgg gtgcgtttcc gcaggtgcgt cacccctttg
     5221 gcggtgggag cgggagtact ccttcacgga gtgttcggcc cgcggacccc cgctctttcc
     5281 gtgtgcgggg catgaattga cgcagtggcg ggaacgcgca cagcccgccc ggcagccggt
     5341 cgtgcgggag tccgggtgcc gggacacgct tacgctgggc ggatcgccgc atcgccgtaa
     5401 ccgcattgtc gctgtatcga gaccacctgt accgaggagg ggccatgacg cttgcccagg
     5461 ctgaacgggt caagtggcag ggcgggtggc agcggacctc ggtacgctcc atggccgtcc
     5521 tgatccccgt actcgccctc gcggtgctcg cgggccgccg ttggtcgctg atcgactcca
     5581 gcgccgacca gctcggcgcc gccgaccgcc agtggctggc cgtcgcggcc gccgccgccg
     5641 tcatgacctg gatctgctcg gccaccgccc agcagggcgc ggtggtggag tcgctgccgc
     5701 cgggacggct gctcgccacc cagttcgccg cgtccgccgc caaccacctg ctgccggccg
     5761 gagtcggcgg caacgccgtc aacctgcggt tcctgctgcg ccgcggactg ccaccgggcc
     5821 gctcggccgc cgccctgggg gtacgtgccg tggccgccgc ggtggtacgc gtcggcatgc
     5881 tgctgatact gctcgccgtc ttcccgcacg cgctcaaggt cgaccgggtc accccggccg
     5941 gccccgccca ccccgtcgtc atcgtgtcgg tggtggcggg ctgcgccgtg gccggcgcgc
     6001 tgctgctgct cctcgccggc cgggtccggg accgggtgcg caccttcttc ggcacgatgg
     6061 tggtcgatgt gcgggccctg cactgcaagt cggcacgggt cgcggccctg tggggcggat
     6121 cgctggcctt cccggtgatg cacgcgaccg tgctggtggc ggtgatccag gcgctgaacg
     6181 ctcccgtgcc ggtcagcgga gtcgtcctcg cgtacctctt cgcgagcacc gccgcggcct
     6241 ggctgcccgc ccccggcggc ctcggctcgc tcgacgccgc cctggccttc accctggtga
     6301 ccgccggcgc ctcggccgtc gtggccacgt cggccgtcct cggctaccgg ctcgtgacgg
     6361 tctggctgcc gctgatcccc ggtgtcctgg tgctcgccgc gctgatgcgg cgccgcgtgc
     6421 tctgagcgcc tgctccgcgc cggcccgagc tgcggccggt ggtcacagcg gccgggagta
     6481 tggtgcggtc ccatggtgga accacgggtc gatccggcag gtcgggggcg ggtcctcgtc
     6541 gtcgacgacg acgcggcgat ccgccgctcg ctgggccgcg gcctgcgcct ggacggcttc
     6601 cgcgtcaccg aggcggacgg cgggcgggcg gcgctcgccg ggctgcgcga cgacccgccg
     6661 gacgtggtgg tgctggacat ctccatgccc ggcatcagcg gtatcgaggt gtgccggacg
     6721 ctgcgcgagg acggcaacga cataccggtg ctgatgctgt cggccctgga cgaggtcgcc
     6781 gaccgggtcg ccgggctgca ggcgggcggc gacgactacc tcgtcaagcc gttcgccctc
     6841 gacgagctgg tgctgcggct gcacgcgctg ctgcgccgcc gcccgccccg gcggacggac
     6901 accgtgcgcg ccggcggcct gctgctcgac ccggcggccc gcaccgcaca cctcgacggc
     6961 accgagctgc acctcacccg ccgtgagttc gagctgctgg agaccctggc ccgcaacgcg
     7021 gggatcgtgc tcacccgcga ccagctgctc gaccgggtct ggggctacga cttcgacgtg
     7081 cggaccgatg ccgtcgacac cttcgtgagc tatctgcgcc gcaaactgga ggccggtggc
     7141 cggtcgcgga tcgtgcacac ggtgcgcggg gtcggcttcg tgctgcgcga cagcccggcg
     7201 gagggcgcgc gatgaccatg cggctgtcga cgcggatcgc gatcgccgtc ggcgtgctcg
     7261 ttcccctcct cgtgctcgcg tcgggctggc tgctggtgcg gctggtcgcg aacgatctgc
     7321 acgcccaggc cgacgcccat ctgcgggaac gcgcggcggc gatggcgcag gacgcccgca
     7381 acctgctgcg ggtcaccgcg gcggaccggt cggccgccgc cgagcaggcc aaggagaagc
     7441 ggctgttcac ctcggcgctg gacgtcggca tccggctcat cggcccggat ggcaccgtga
     7501 ccggcgggcc gcagcccggc gcgtccttca cgctgcccgc cgacgcccgc cggccggtca
     7561 ccgtccgcga cgggcagcgg agctggcggg tgctgtcggt gccggtggtc gccaagcgcc
     7621 cggcggcgac cggcaccctg tggatcttct cgccggacac cgcgagccag tcgcagatcc
     7681 agctcgtgcg gcggcgggtg gtgatggtgg cgctgctggg cgcgccgctg gccgcggccg
     7741 tcacctggct cgccgccacc gccgccgtac gcccgctgcg caggctccag cggcgggccg
     7801 ccggcctcga cccgggcacc agcgcggccc ggctcgacca cgagccgtcc aggatcgcgg
     7861 aggtcgacga cctggcgctg acgctgcgga cggtgctgtc ccgctacgac gaacaggccg
     7921 cgcgcaccgc cgaggcgctc gccacggccc gctccttctc cgccgcggcc tcgcacgaac
     7981 tgcggacccc gctgatgagc atgcggatca acctggacgt actgggcggc caccccggcc
     8041 ttgaccccgc cgaacgggcc gagatcgtgg cggacctgag ccgggagcac gcccggctgc
     8101 tcggcctgct ggtgatgctg cgggcgctgg cgcagggcga cctcgtggag gccgacgcct
     8161 tcgggcccgt cgatctcgcc gaggtcgtgg agtccgccgc cgccgcgctg cgcggcagcc
     8221 ggccgggcac ggcactgacc gtgcggagcg ggcccgggct cctggtccac gggtgggaac
     8281 cggggctgcg ctcggccgtc gacaacctga tcgtgaacgc gctgacgcac gggggcggcg
     8341 cggtcgacgt gacgctgagc gccggggagg acgggcacgg gccgggtgag gtcgccggtc
     8401 cgttcgtcgt gctcaccgtg gacgacgacg ggcccggggt gccgccggcg tcccggcagc
     8461 gggtcttcga gcggttccgg cgcggctccg acagttccgg ctccggcctc ggtctgacgc
     8521 tcgtcgcgca gcagatctcc ctgcaccggg gcacgatccg gattctggac cggccggccg
     8581 gcgagggccg tgccgcccgg ggagcccggt tcgaggtacg gctcccgctg gccgtgaccg
     8641 gccggccgga ctccggactc ccatcgcgca gggactggtt gagcggggaa acggcgacgg
     8701 gaacgggacc agtgacggga ccagtgacgg accggtgacg ggaacggcgc ccggtcaggc
     8761 cccacaaggt ttccacaaag accgctccta gcgtcgttcc gcggccgggc accgtgcccg
     8821 gtccgtcgag gaggacacca tgcgcaccac tcgcaccacc cggacggcga tcgccgcgtg
     8881 cgcggccgtc gccgcgctgc tcggcgcggc gggaagcgcg gccgccgcgc cgtccgcgcc
     8941 cccgaccggg gacggcgcca aggcggtctg caagcgcgcc cccaaggccg acgcgcggat
     9001 cgacaaagcg ctcgcccggc tcaacgggaa cgccgccacg aagggatccg tcgcccggct
     9061 cacccagcgc gtcgccaacg ccaagtcggc cggtcacagc gagatcgaga cctatctcaa
     9121 cgaccggctg accttccgca agtcgctcgt gccgacgctc cagcagcgcc agaaggacct
     9181 caagtcggtc ctcgtctggt gccaggccaa caacagcgga acctcgaagt gaccacggga
     9241 tcacggctgg ccgcggtcac cgcgacggtg ctgctctgcg ccgcgctcgc caccggctgc
     9301 ggtgacaagg gcggtggcgc cgacgggtcc gccaccattc ccacgccgtc cggttcgcag
     9361 ctcgcgcacc tcgacaaggt cgtcggcgac gcggagtcgg cggcgaacgc ggcggagtcc
     9421 gatgccgcgt ccgacgccgc gtccgacaac tgacggacgg ctcacgtaac ctgtgcggcc
     9481 atggagtcga tggcacggac tttgtggctg cgcacggaac cactgcacgc ggtggtctac
     9541 ttcgacgcgc agtgccgcga gatggggcgc tcgctgggtc tcaagggcta ctggatgggg
     9601 tacttcgcca cccggtccgc cccactgggc cgcgcacagc cgtcggtggt gaccgccgcg
     9661 ttcggtgtgt tcgcccccgg accggtcgcc cgcgcgctgc ccgcgtcctg ggacatcacc
     9721 acccccgagc gggcactcga cctgcgggtc gaacgctcgg ccgccgccct gcgggcgctc
     9781 gatccggaac tggagcgccg ggcggagcgg ctgaccggtc cgctgggcgc gatggtggcg
     9841 gacgcacccg cactcgcccg gccggtgttc gccgccaacc gggccctccc cgaccgggcg
     9901 gaccccgtgg agcaggtgtg gcaactgacc acctcactcc gtgagttccg cggtgacgcg
     9961 catctggccg tactcgccga ccgcggcctc gacggctgcg aggcactgct cctcgcggcc
    10021 gccgacggcc gggtgcccgc cgactccatc cggcaggacc gcggctggac ggcggaggaa
    10081 tgggcgggcg ccggtgcccg gctgcgcgaa cgcggactgc tcgcggcggg cggtgccctc
    10141 accgaacgcg gacgcgacga gcgccggtcg atcgaggacg acaccgaccg gctggccggc
    10201 cgtctgctgc gcccgctgtc cggcgaccgc gcgcaggcgc tgttcagcga cctggccccg
    10261 gtggtggacc gcgtcctggc cggccaggtg ctgccgttcc cgaacccgat cggcctgccc
    10321 cggccggtgc ggccgctgta gccgggtagc cgatcggaac gagccgggtc gtcggaccgc
    10381 gaagctactt ggcgtcggcg tagcactcca cgacgttcgt ctccagcggg aagcggaccg
    10441 gggtgtcgcc gaagaccagg cggcgggcct cctcgcccgc cgcggcgacg gcggcctcga
    10501 cggggcccgc gaggccggtc ggggtgtgca cgatgatctc gtcgtgctgg aagaagacca
    10561 gttgcggctc ggggccgatc gccgcgaggc ggcgccgggt ggcggcgagc atcgccaggg
    10621 cccagtcgga ggcgctggcc tggatgatga agttacgggt gaagcgcccc caggaacggg
    10681 cggcccgccg gtcgggcgag gagccgtcgt cggaacccga tcccgaaccg gatccggaac
    10741 ccaggtccgc gtcctccgtg tccagccagc cggaggccgg cgtcggggag gtgcggccca
    10801 gccgggagcg gaccacgccg ccgccttcac cgatgcgggc ggcggattcg acgaggccca
    10861 tcgcgtcggg gaagcggcgg cggagaatcg cgagcagctg acccgcctcg ccgctggtct
    10921 gcccgtacat ggcggccagc aggccgatct tggcgcggct gcggtcgccg ccgaacgcgg
    10981 tgcgcgcgat gcccgcgtag agatcgccct ccgccgccgc ggcggccagg cccgtgtcgg
    11041 ccgacatcgc cgcgagcacc cggggctcca gctggcctgc gtcggcgacg accagccggt
    11101 ggccggggtc ggcgacgacg gcggaccgca gcagccgggg gatctgcagg gcgccgccgc
    11161 cccgggtcgc ccagcggccg gagaccaccc cgccgacgac gtactcggcg cggaaccggc
    11221 cgccgcgcac ccagctctcg cgccaggccc agccgtgggc ggcgtggatc ctggacagtt
    11281 ccttgtagcg cagcagcagc gccgccgccg ggtgctcgac ctcgcgcagc acatgcgagc
    11341 gggtcgacgg cagctggacg ccgacccggg cgaaggcggg cagcacctgg gcgggggagt
    11401 ccgggttgac cgggctgccg agcgcctcct ggacctgggt cgcgagttcg cccagcagct
    11461 tggggcgggc gccgcccgac gggcgcgggc ccagcagacc ggtcagcagt tcgtcgtgca
    11521 cggcggcgct ccacggcagt ccgccgcggc ccatctcggc ggcggccagc gatccggcgg
    11581 actcggcggc gcacagcagc cgcatccggc ccgggtgctc gccctcctgg agccggcgct
    11641 gctgctcggc gtgcacggcg acgacggccg tcagcggatc ggcgtcctgc ggcaggtggt
    11701 gccggtcggc cgcgaagagc accggctggt cgtcggccgc gccctcccgg gcgtcctcgg
    11761 ggaccggcag atccttcagc cgcgcccacg cggcgccgag cgagcgcggc tgtccgtgcc
    11821 ggccgtcccg gccgagcagc agcgtttcga cgagtttcag atcgtggcag cgggccggcc
    11881 gtaccggcag ccggtcgagc agccgggggt acaggtcctc ggtcgccgcc cacacccagc
    11941 gcggcccgcc ggacgcctcg cgggcggcga tggcggcggc gagatcggcc acccgctcgg
    12001 cggacccggt cggtacgccc tcctcgtcca gcaccagcag ccgcccgccg tgccccacgg
    12061 ggtcgggtgc gacggcgacg cgtggcgcgg agggcagagg agtgctcacg ggtcgagcgt
    12121 agagcggggc actgacaacg ggccgtgtgc aaggcggccg gtcagcggtc caggagcgtg
    12181 tcgcggtgct gggcgcggta ctcgtcgagc agcgccatcc ggtccgccgt ggtgaagggc
    12241 cggtacgccg cgccgcaggg gcccgcgtcc ggcggggacc accagaccgg atccgcgcac
    12301 gagaagccgg tgcggcgcag gccgacccgg tggaccttgt tggtggcggt gaccggcatc
    12361 cgcgcggtca cgcgcacgaa gcgcggcggc atcttcgtgc ccagatccgg ctgggcggcg
    12421 aggaaggcgg cgaacgcggc cgggtcgaag gcggcgccgt cgtgcagggc gagggtcgcc
    12481 atgacctggt cgcccgccac cgggtcaggg acggcgtaga cggcggccga ggctgcgtcc
    12541 gggaagcggg ccaggatgtt ctcgatgacc gcggcggcca ggttctcgct gtcgacgcgc
    12601 agccggtcgt cgctgcgccc ggcgaagtgg aagaagccct cggcgtcacg gaagaacaga
    12661 tcgccggtcc agtaccagtc gccgcgcagc cggtcggcga cggcctgctc gttcttccag
    12721 tagccctcga acgtgctccg gccgcggttg accagctcgc cgatcgcctc gtcgccgttg
    12781 agcagccggc cgtcggcgtc gaaacgcgcg ggcgggcgtt cccggccggt gccggggtcc
    12841 acgacggcga gatccgcacc cggggcggcg cggccgatgg cgccgggtgg tgtgccgggg
    12901 gagcgctgga tggcggcgcc gccctcggag gagccgtacc cctcgatgag cggggcgccg
    12961 aagcgggcgg cgaagcgggt ggcgtcgacg gccccggcct cggtgccgaa gccgtgccgc
    13021 agtgggtggt cgcggtcgtc ggggcgttcg ggggtcgcga gcaggaactg cacggcgcgg
    13081 ccgacgtagg tgaagtacgt ggccccgtag gcccgtatgt cgggcaggaa ccccgaggcg
    13141 gagaacttcc gggtcagggc gactgcggcc ccgccggtca gtgccggggc ccagttggcc
    13201 atgacggcgt tgccgtggaa cagcggcatg cagatgtagt ggacgtcctc gggcaccacg
    13261 cccaggaagt cgaccagtgc ctgcccggcg tgggcgaggc ggccctggga gcagatcacc
    13321 gctttggggg tgccggtcga gccggaggtg aagtacagca gcatccgggt cccgggcgtg
    13381 acctccggcg cgggttccgg ctcggcgccc gcgtacgggg cgagcagcgc gtcgtacgcg
    13441 gggtcgtcga cgacgaggac gcggtcgcgg gcgagcgacg gtcccaggtc gaggccgtcg
    13501 agcagcggga ggtgggcgcg ttcggtgacc agcagggcgc attcggtgtg ggcgatgtcg
    13561 cgggccagtt ccgggccgcg ccgggtcggg ttgacgccga ccacggtggc tccggcgagt
    13621 gcggccgcgc ccagccacag ggggtactcg gggacgttgt ccagcaggac gccgacatgc
    13681 ggctgcgctc cgggcggcag cagatcgcgc agcagcgcgg cgcgggccgc cgacgcggcg
    13741 gcggtctcgt ggtgggtgag gaccagatcg cggtacttca ggcccggccg gtggtccttc
    13801 caccgcgcgc gcaccagctc cgcgaccgtg gtgccggccg cggagccggt gtccggggtg
    13861 tgagcggccc ccgccgtgtg cgtgctcccc atcgccgcct cccgtccgtt ggacagcaag
    13921 cggcaccata actgactagt cgtcagatgt ggagggggcg atcgacggcg ggggccggtg
    13981 cgagcggtcg gggtgctgcg tcaggaaccc tgctgagcct gctcgacgga cttgcggacc
    14041 tcgtccatgt ccagcgcgcg cgcctggccg atcacatcgt ccagggccgc ggccggcagc
    14101 gcgccgggct gggcgaagac ggcgacgcgg tcgcggacga tcatcagcgt cgggatcgac
    14161 tggatgtcga acgaggcggc cagctccggc tgcgcctcgg tgtccacctt cgcgaagacc
    14221 aggtccggat tcgcctcggc ggccttctcg tagaccgggg cgaacatccg gcacgggccg
    14281 caccaagcgg cccagaagtc gatcaggacg aaatcgttct tggtcacgac ctcgtcgaag
    14341 ttgtccttgg tcagctcgac agtgctcatg gtgcgcataa cggggtgtgc cgatcggata
    14401 ttccggcgac ttcactcatc cgggtgatgg ggtgaccggg tgcagtggcg atcagtgggt
    14461 gggtctcgtt ggtcctgtca tgggaacgac ggaatgggcc cgggacagcg gcggtgcgaa
    14521 cgacggagcc gcctggcgcg tcacccgggg tggaacgatt ccgcacggct cggacgtccc
    14581 ggtgtacgcc gccctggccg accagtggcg gtcggccggg cggatggtac cggggcagat
    14641 cgacgcggag tgggccgagc tggtcggacg gatcccgcgg ttgacggggg tgtgacgacc
    14701 ggaagcggga tgtgacggcc gcagtcggga tacggcggga gagcggccac gaacggccct
    14761 gccgcggtcc gggacgcctc agccctcgtc gaagaccagg tcctcgggcg gacggttcat
    14821 ccgcaccgtc tggcccgaga cctccaccac cgtctcgaag ccggtgtact ggccgcggga
    14881 cacgatcagc acgcggtcgc cccgctggtc caggaaggcg gcgaacccgg ccagcgacgg
    14941 gtctcccgcg cccagcgcca ggtagtccgc cagccgacgg aacagcttcg gcatgatcac
    15001 ggcctccgag gtgatcgact ccaggccgtc gatccgcgcc cctgactggg tgacgtccag
    15061 cgaccacagc ccgacgccct tggaccgggc cgcgtccacc gccgcggtca gcgcctggcg
    15121 cagatccacg tacagattcc ggtagtacgt cggataggcc aggccctccg cgagctggtg
    15181 gaagttggcc gtctcctcca gcagcgccgc ctccacccgg atccgttccc cgctggtgcc
    15241 cggcgccgcg cccttgccga ccagggccac gcaccgcccg tacagatcgg cgccgcggct
    15301 gaggaggtag ccgggcagct gcgccggctc cgccgcgctc acggtgccgt gcccgtcgcg
    15361 ggtgaccccg gtgaagccca gccaggacag cagctccccg gcggcctggt cggcgtacgg
    15421 cgccggctgg tgcagttcat ggccgtgcgc cggtatgtag tgcgtctcca gggcgtcgat
    15481 cgcgtccagc cgcagctgcg cgccgcccgt cgcgttgcgc tgcacccggt gcttgccctc
    15541 caccaggtcc cagtgcgccg gatcggtggg gtagaagcgg atggagtccc cgtcgggacg
    15601 ggctccggtg atccggtacg tgccctcgat gacgagcatg ggcatggcga cgcctcctca
    15661 gcgtgtccac gtatccgccc ggtcggcgcg gccggctgtc cgccgcgggc cgcccgcgga
    15721 tcctcggtgg atgtcccgcg cggttccctt ccctccagcg tgacgcagaa atcccggcgg
    15781 caccggggac cggccggtaa cggcgggctg aattcttctc atcaacccac agcgtggacg
    15841 cccccttgag ctggattcga gggccggtac acatcctcgg acgcatcgcc cggagtgacc
    15901 cgaaaggaac ctgctgtgaa cgtacgcgcg acgttccaca agccgggacg gcggccatgg
    15961 tgacggtcct gcggcgcgcc ggtgccgggg aaggcgccct ggcggtcccg caactgcgcc
    16021 attcgtcctg ggagctggcg gcccgcttcg accgggagct gggggacccg ggcgaccctg
    16081 ccaccgtctt ctcctaccag gaagccgtcc ggctggacga cgccgaggag ttccccgacg
    16141 aggcgtgcgc cgccctcgac gcctggggcc tcgccgacta ctacgtgccc gccgactacg
    16201 gcggggtgct caccggcttc gaggacctgc agcagctcat ccggatgctg gcccggcgcg
    16261 atctgacggt cgccgtcgga cacggcaaga ccttcctcgg ctcggtgtcg gtgtgggtct
    16321 caggcgacca cgcggcggcg gtccggctcg gtgcgctggt caaggcgggt gcccgcgtct
    16381 cgctcggcct gacggagcgc acccacggca gcgacatcat ggcgggcgag ctcaccgcgg
    16441 aaccggtcgg ccccggctac cgcgtcaacg gcgagaagtg gctgatcaac aacgccaccc
    16501 gcggccggct gctcagcctg ctcgcccgaa cgtcgcccgt cggcggcccg cgcggcttca
    16561 ccctgctcct cctcgacaag gaggaactgc ccgaggagac ctaccgctgc ctgcccaagg
    16621 tgcccaccca cggcatccgc ggggcggaca tcagcggcgt cgtcatccag gacgcggtgg
    16681 tgggcccgga ggcggtggtc ggcggggccg gcggcggtgc ggagctgctc ctcaagtcgc
    16741 tccagctcac ccggacgctc tgcccgtcgc tgtcgctcgg cgcggccgac cacgcgctgc
    16801 ggctggccat ggagttcgcc agtgagcggg tgctctacgg ccgacggctg accgaactcc
    16861 ccctcacccg gcgcaccctg gccgaggctt acgccgacct gctggtctgc gaggcgctga
    16921 gcacggtggc gacccgcagc atccacgcgc tgccgagcga gctgagcgtc acctccgccg
    16981 tcgccaagta cctcgtgccg accatcatcg acggacaggt cgcctcgctg ggatccctgc
    17041 tgggcgcacg gtcgttcctg tcgggcgagt tcgcccacgg cagcttccag aaggtggccc
    17101 gcgaccaccg catcgtcggc atcttcgacg gcaacaccct cgtcaaccag tactcgttgg
    17161 tggcgcagtt ccgttcgctg gcccgcaact acctcgggcc gctggaccac cgcccgcggt
    17221 tgggcaccct gttcaacctg agccggccgc tgccgccgtt cgaccccgag cggctcaccc
    17281 tgctctcccg ctacggcagc agcgtcctgg gcaccctgcc cgcctccgtg acccggctgg
    17341 cggacgcggc gctgctcgac cccgcgctcg gcggcgccgc ccggtgcgcc gcggaactgc
    17401 gggtggcggc cgacgcgctg caccgcagga tcgcccgccg gatggaaacg gtggcggccg
    17461 cgtcacccga gagctttacc gacgcacgca agtacgggct ctgcttcgcc ggggccgcct
    17521 gcctgggact gtggctgcac agccaccgtg aggcggaggc gggcgggacc ggcgggctct
    17581 ggcaggacgg tctgtggctc gaagccgtac tgaaccggct gctggcccgc ctggaggcgc
    17641 gcccggccgc gggcgccgcg gaggacccgc tgttcgagcg gctctacaca cagctgaccc
    17701 agcagtacca ggacggcagt ctcttctcgt tgctgccctg cccgatagcc gagggaccgc
    17761 catcatgctg aaggacaaca gctcccgccc gcagccgggc cccgtcccgg acgccggacc
    17821 ggcgcagccg gccgggctcc ggtcggtgga cccggcggaa gtcgccatcc aggccagggt
    17881 cgccgaactg gagcaactgc tcggcgaccc ccgcgacccg gacaacccct tcgggcacga
    17941 cgcgttgctc gccgccgacg accgcagcga actcctcccc tccgcggagg acgcgctcac
    18001 cggcttcggc ctcaaccacg agttcgtgcc ggtggaactc ggcgggcggc tcgcccgggt
    18061 ggacaccctc gcccgggtgc tgcgaccggt cttccgccgg gacgcctcac tcgcgctggg
    18121 ctacggagtg acgtccttcc tcgccgcggt cgcggtgtgg gcggccggta cgcccgagca
    18181 gcgccgctgg accgccgacc tgctgatggg cggcggccgg ctggccatcg cctaccacga
    18241 gctggcacac ggcaacgact tcgtccgcaa cgagttcacc gcgctccccg acggcaccgg
    18301 cttccggctg gacggccgca aggaagtgat caacaacgcc gggcgcgccg aggccctcgt
    18361 cctgttcagc cgcaccgcga aggaggccgg cgcccgcagc cactccgtgc tgctcgtcga
    18421 caagagcgtg ctccccgccg accggttcga gcatctgccg cgctaccgca cggtcggggt
    18481 gaagggctgc gagatcggcg gcttccactt ccgtgactgc ccgctgcccg gcgacgcgct
    18541 cgtcggcggg ctcggcgaag gcgtggagat cgccctgcgg tccttccaga tcacccgcag
    18601 cgccattccc gcgatggtgc tggcgggcgc cgacacggcg ctgcgcaccg tggtcggctt
    18661 cgccgtcgac cggcagctgt acggccgttc ggtactggag atcccgcacg cccggtccac
    18721 cgtggcgggc gccttcaccg acctgctgat ctgcgactcc ctcgcgctgg ccgccacccg
    18781 ggcggtccat ctgctgcccg gccagaccag cgtgtacgcg gcggtggtga agtacctggt
    18841 gcccaagttc ctgcaggacg ccacctacga cctctcgatc gtgctgggcg ccaacttcta
    18901 tgtacgcaac ggcgagtacg gcatcttcca gaagcacgta cgcgacctgc cgatgaccag
    18961 cctcggacac gccgggaccg ccgcctgcca ggccacgatc attccccaac tgccgcggct
    19021 ggcccgcaag tcgtggttcg ccggcgaacc cgcccccgcc tcgctcttcc gcagctggga
    19081 gggtctgccg ccgctcgaca cgagccggct gtcgctcgcg gcggacggtg acgcgctcgc
    19141 cgcctccctg gtgaccgggt acgactggct gcgggccacc ggcagcgggg ggaccgacgc
    19201 ggccgcactg atcgaactcg tccgctcgct cgtcgaggaa ctgcgcgaac tgcagggcga
    19261 gtgcacggag atgccgcccg aggaccgcac cgtactggcc agcccgcacg cctacgcgct
    19321 cgccgaccgg tacgccctgg tgctcgcggg atccgccgtc ctcaacgtat ggcgcgaaca
    19381 actggggggc ggctcgccgt tcctggccga cccggcctgg ccgacggccg cgctcgcccg
    19441 gatcgcccgg cggctggggc tgcccgtccc ggaacgcacc cgggacgagg tggactggct
    19501 gctcggcgag gtcctcgacc gctaccacgg cgaacgcagc tacgacctct acgacagccc
    19561 cctggccggt tgagcggcac cgagacacaa gaggagtcgg acatggtggt tcccggcagc
    19621 gctgtccagg agcgggagtt tcgcgggtgg ctcctggaga agctcggcca gtacctgcgg
    19681 cgccccccgg cggacatcga catcagcgtg cccttcgcgg agtacggcat cgactcggtg
    19741 gccgcgctga gcatcttcgg tgacatcgag gacggattcg ggctctacct ggagccgacg
    19801 gtggcctggg accaccccac ggtgcagtcc ctcgcccgct atctggcctc cgagtccgcc
    19861 cgcagcgcca ccggcccgct gacgcaggcc ccttacggcg aaccgatcgg cgggaaccag
    19921 gcgggcggcg acccgagcga cccccgcgac acccccggga cggcgggctg gacgcggaac
    19981 accccgggag gtggaccgcg gtgaacccga tcgccgttct cggcctggac tgccgcttcc
    20041 caggggcccc cgacccgggg gcgtactggg acctgctcgc cgccggagcc gacggggtcg
    20101 ggccgagacc cgcctcccgc cgggtcgggg acacccggcg ggcgagtgtg cccgcggccc
    20161 ggcccgacgg cggattcatc gacgacgccg acgcgttcga ccacgccttc ttcggcatcg
    20221 gccgcgccga ggccgccgcc atggacccgc agcagcgact gctgctgcag accgcctggc
    20281 gcgccctgga ggacgccggc atcaacccca gggacctggc cggcagcggc accgggatct
    20341 acgtgggcgc catggccgac gactggtccc ggctgcggct ggccgacgac gcggcgatca
    20401 ccccgcgcac cggcacgggc gccggccggg cgatcctcgc caaccggctc tcgtaccagc
    20461 tggatctgcg cggtccgagc ctcaccgtcg actccgcctg ctcgtccgcg ctgatcgccg
    20521 tgcacctcgc gatgggcgcg ctgctgtccg gcgaatgcga catcgccctg gcctgcgggg
    20581 tcaacctggt gatgtccgac gtcctggacg agatctacgg ccagtccggg ctcgccgccc
    20641 cggacggccg ctgcaaaccc ttcggcgcgc aggccaacgg catcggccgg gccgagggcg
    20701 tcggcgccgt cgtcctgcag cgactggagg gcgcccgcga cgagggccgt ccggtccgcg
    20761 cgctgctgct gggcagcgcc gtcaaccagg acggccgcag caacggcatc atggccccgt
    20821 cccggcgcgc ccagcgcgag gtcatccagg ccgcctgcaa gcgggccggg gtcgagccgc
    20881 agcggatcgg ctgggtcgag gcgcacggca ccggcacccc ggtcggcgac ctcatcgagg
    20941 cccgcgcgct cggcgacgtg tacggcgggc tgcggccgga gccgtgcgcg atcagctcgg
    21001 tgaagggcaa catcggccac gccgagggcg cggcgggtat cgcgggcctg atcaaggccg
    21061 tgctggcgct ggagcaccgg ctggtcccgc cggtcaggac cgtgggcggc gagcacccgg
    21121 gactcgacct ggcggcgcac ggcctgcggc tgctgaccga accgctgccg ctgcccgagg
    21181 gcgagatgct cgccgccgtc tccagcttcg gcatgggcgg cagcaacgcc catgtggtgc
    21241 tctcctccgc gccccggcag accgccccca tcgccgcccc gcagaccaac aacggtgaga
    21301 gcggtgagag cccgggggtg ttcacgctga ccgcgcccac ggccgaggcg ctgcgccgca
    21361 atctcgtcgt ccaggcccgc tcgctcgcgg cccgcgccca ggagccggtc actccgctgt
    21421 gctggaccag caacctgacc cgcaccggca tggcgtaccg gatcgcgatc cccgccgagg
    21481 acaccgccgg gctcgccgcc gccctggacg ccgccgcgga ggcgggcgag ggcgtgccgg
    21541 agccgccgga acccccggtg gtggcgttcc tcttcaccgg ccagggcgcc cagtaccccg
    21601 ggatgacgag ccggctgtac cgcgagtcgc cgctctaccg gcactacctc gacgaggcgt
    21661 cccgggccct ggaaccgcac ctcggcggtt cgatcaccga gctgctgctc ggccgtgacg
    21721 agcgggtgca ccgcaccggc tggacccagc ccgccgtctt cgccgtgcag tacgcgctgg
    21781 ccggctacct ggaggagctg ggcgtgcggc ccggcgccgt actcgggcac agcatcggcg
    21841 agttcgcggc ggccgtcacc gcgggcgcgc tcggtctgga ggacgccgcg gcgctcgtcg
    21901 cggcccgcgg caccgccatg gaggcgctgc ccgagggcgg cgggatgctc gccgtgcggg
    21961 cgcaccccga cgacctgcgc gaagtcctcg cgggcgaacc gctggtgggt ctgggcgccg
    22021 ccaacggcgc tgccgcgtcc gtgctgtccg gcgatctggc gggcctcgcc aggatccgcg
    22081 aacagctcgc cgcgcgcggc gtcggctgca ccccgctcaa ggtctcgcac gccttccact
    22141 cggtcctgat ggagccggtg ctgcccggct tccgcacgac ggctgatggg atcaccgcgg
    22201 gcgagccgcg cattccgttc ttctccaccg tccgcggcgg cctgctcgcc ggacgcccgc
    22261 tcgacgccga ctactggtgc gaacacatca ccggcagcgt ccggttcgcc gacgccgccg
    22321 ccgcgctgct cggctccgac gtcacgcatc tcgtcgaact cggccccaaa cccgtcctgc
    22381 tgccccttgc ccggcggctg cccggaggca gcgggctgcc cgggatctcg gtcgtccgtg
    22441 acgcccacag cggcgcgctg accgcggccg aggcggcggc cgcgctctac acggccgggg
    22501 tcgacatccg ctgggagctt ctctaccgcc ccgaggacaa ggtgcacgcc cagctggcgc
    22561 cgcagagctt cgatacctcg gcccggttct ggtacgagcc accccgaccc gcggcggcgc
    22621 cggccggcga accggggagc ccggtcctgt cgctggtgcg cgcggactcc ggcccgcggg
    22681 cacccgagca cgacggcggc gggctcgccg aggcggtgcg cgagacggtc gccgggatca
    22741 ccggcgccga ggagggcacc ctgcgcgacg acgaccggtt ctacgacgac ctgggcttcg
    22801 actcggtgat gttcatggag ctcaagtacc ggctggagga ggcggtaccg gcgctgggcg
    22861 agctgtcgat cccggagatg atgtcgagcc tggtctcggt gacgaccctc atcggctacc
    22921 tgcgtgagca gctcgccagg gtccccgcct gatgacccgg cgcccgccct cggagcccgg
    22981 catgcacctg ctcgcggctg ccaccgcgct gcccggcccg gcgatcggca acgaggtgct
    23041 ggccgggcgg ctcgggctct ccgccgagtg ggtggagatg ttcatcggca cccggacccg
    23101 gcacttcgcc gtggacctcg cgggcggcgt cggctgcctg ctggccgacc tgtgcgaaca
    23161 ggccgccgtc cgcagcctgg agcgggccgg gctgaccgtg cgcgacctct ccttcgtggt
    23221 gctggccacg gcgaccccgg actccctgat gcccaccacg gccgccgtcg tcgccgaccg
    23281 gctgggcgcc gccggcatcc cggcctacca gctgcagtcg ggctgctccg gcgccgtcca
    23341 ggcgttcacc ctcgccgagg cgctgctcgc ccagcagccc gccgggcccg gcgggccgta
    23401 cggactggtc ctcggcgggg acgtctgcgc caaacacctg gacctggagc aggacttccg
    23461 ccggatgccg cccgcccagc tcgtcaacta cgtgatcttc ggcgacggcg cgggcgccgc
    23521 cgtggtgagc gccgccccgg cccccggcag cgccgccttc cacgggctcg ggaaccggct
    23581 ggccctgccg ggccagccac cgggccagca cgtcgagtgg tacggcgccg ccgaccgcga
    23641 cagcgcgctg ccgccggtct ccgaggacta caaggccgtc gagttcctgg tcccggaact
    23701 ggcccaacag gtctgcgccg acctgctgga caccctcggc tggtcggcgc ccgacctggg
    23761 ctacctgctg ccaccgcagc tcggcggtct gatgacccgg cgcatcaccg ccgcgctgcg
    23821 cgccgggctc ggggtggaga aggcggtcga gatctcctgc gtggccgaca ccggaaacac
    23881 cggtaacgcc ctcgtgctga gccagctgga acagctgctg cccctgctga ccccaggagc
    23941 gcgggcgctg tgcgcctgcg tcgagtccag tcggtggatc tcggccggtt tcgccctgga
    24001 ggcgtcatga ggaccgtgca ggacaacgga atgaaggagg aggcacagtg acaggagtcg
    24061 aggacatgat caccctgctc aaccaggaac tgggcctgtt cctgcgcccg gaggacgccg
    24121 ggtcgcccct ggacgcgctc ccgggctggg actcgctact gctgttccgg ctcgtcgcgg
    24181 tactggagga ggaggccggg cggccgctgc cggtcgccga ggtcgtcacg gcgggcaccc
    24241 tcgccgagat ccacgcgctg gcggtggggc tgtgacgccc caggccgcgt cgggtcaggc
    24301 cgggacaggc cggaccacgg cacgtcagga caccgcgcgg tccgaccggg cccgccgcca
    24361 cacccggtac ttcctgcggt gggcccgtgc cgcggccccc gtgcacctgg gcgccgacat
    24421 cgacatgacc ggcgtccagg cacaccgggc cgcggcccgt gccgagggcc gcaggtactc
    24481 cgtggtgagc tatctgctgt acgccgccgg ccgggtactg gccgaccacc cggaggccaa
    24541 cgcgacgacg gccggcggta tcgtgccgcg caccctgcgc tacgaacggg tgcacgcgaa
    24601 gctggccatc gacagcggaa ccgccgacga gggccggcgc gcggtgcgcg tggcggtgct
    24661 gcccgacgtg gaccggctgg acctggccgg aatccagcaa ctcgtcgacc gctaccggaa
    24721 cggagccgcc gaggacctgc cgggagcgga gggggtgcgc cggctcggcc ggctgccccc
    24781 gccgctcggg cacctcgcct tccggacggc cgtgagcagc ggggcccgcc gggccgaact
    24841 gctcgggacc gtggcggtca gctctctcgg ccaccgcagg gtggacacct tccactccta
    24901 cggtggtacc gcggtcaccc tgaccgcggg ccggatcgcc gaggttccgg tggcccgtgc
    24961 gacgcgagtc gccgtggcgc cggtgctgcg cctgggtctg accttcgacc accgcgtgct
    25021 cgacggcgcg gcggccgccg acgtactgga cgacctggca ctactcctgg aggcatgcga
    25081 tgccgctctt cccggggggt gggacgcccc ccaacgccgt tccggtgatc ggccggccca
    25141 tcagggtgac cagtccggaa ggcccgtggc accgcgtggt tgaggcgctg gacgagcgtg
    25201 gcagcgtcat ggtccacgcc ctgctgtcgg actgggtgcc cgagaacctc gacgacccgg
    25261 agctgcgccc ggtcctcgga cgggactggc accgctacca ggcgatgcgc caccaccatg
    25321 tgcgggagcg cttcgccgcc tcccggctgc tgctcaaaca cgtggcggcg caggcgatcc
    25381 aggccccgcc ggccaccgtg gagctggcct acaagcccgg tggccgcccg tacctgcgcg
    25441 gctgcgacca gatcgacatc agcctcagcc acaccgagga actgctgctg gtcggcatca
    25501 cccggcgcgg ctggatcggc gtggacgccg agctggagga ccgctccatg ctggtctccg
    25561 gcatcgaacg gcaggtgtgc accccgtacg agcgcaccat gctgtcccag gtcagggaga
    25621 gcgaccgcaa ccaggagatg gtgcggctgt ggacgctgaa ggaggcgtac agcaaggcca
    25681 tcggccaggg catgcggttc cggttcaacg agttcggctt cggccccagc gggcatcccg
    25741 tccaagtgct cagaccggac ggctcgcccg gcaccggtga ggagtgggcg ttcggcacct
    25801 gccgcgtcga aggccgctac accgccagct gggcgctgta cgacgcgggc ttcggcgaca
    25861 ccgacgacac ccgggccggc accatgctcg acgagggcct ggtcaccgcg ctgctgcacc
    25921 agccggccga ggcgccgcag ccggccgccg aggccaccgc cgcgaccgac gtgccgctga
    25981 ccggagccgg agtggcggca tgaccgccgc cccgccgccc gccgggaccg acgtggtcgt
    26041 ggtcggcggc gggccggccg gactcgcgct ggccctcgca ctggtacggc tcggggtgcg
    26101 cacgaccgtg ctggaacgct ccgccggcgg ccgccgcgac ttccgcggcg agtcgctgtc
    26161 cccggacggc gtccggctgc tggaccgctg cggcgtcctg gaacaattgc gcgccatcgc
    26221 cctgccggtg cgccggctgg aggtcgccga cggcggcagg accgtactcg acgtcggctt
    26281 cgagtccttc ccctatccgt accgtttccc gctggagatc ccgcagtccc tgctgctcgc
    26341 ggagatcgag gccgcggcgc ggtgccagga cggcttccgg atgctgcgcg gctggaccgc
    26401 caagggcctg ctgtccgcgg acggacggat caccggtgtg cgggccgccg ggcccggcgg
    26461 ggtggagtgc gagatccgcg cccggctcac cgtcggcgcg gacggccgct acggcaggat
    26521 ccgcaaactc gccgaactcg acgcccgggt acggccgctg gaccgggacg tgatctggat
    26581 gcggctgccg cgccccgtcg agtggacgga cgcggcctac cggatccgga tccgcggcga
    26641 ccggcacgcc ctgctgctcc ccgactccgg cggcactgtc cgggtgggcc tcaacatccc
    26701 caagggcggc ctgcgcgaac tgcgcagatc agggctggac gcgttgcacg aacggctcgg
    26761 cgagctggcc cccgaactgg cggagcccgc ccggcagacg ctgcgggact ggtccgacac
    26821 cgcgctgctg gacatcttca gcaccaccgt gccgcattgg tcggcgccgg gcatcgtgct
    26881 gatcggagac gccgcgcaca ccctgtcgcc ggtcctcggg cagggcgtca accacgccct
    26941 cgccgacgcg acggccctcg cgccgctcgc cgccgcggcg ctccacagcg gggaaccagc
    27001 cggactcgac cgcgccacgg gacagttcca gcgacagcgg tcccgcgagg tggcccgctc
    27061 ccggcggctg caactgcgcc aggagcggat cttcacctgg tcggccccgg ccgccgtggc
    27121 ggtgcgccgc ggcgtctacc gggcgctcga ccgctccgcc cggctgcgtg cccggatgct
    27181 ggagccggcg tacttcgccg accagcgggc cgagcgggcc cgcggcgcac ggcgtgagga
    27241 ccacgacgag cacgagcagg aggcgcggac atgaccacac ggctcggtgc cgacgacgcc
    27301 atcggcctgg aggaactgcg cgggctgtcc ctgctgcacg cacaggccca gggcatcgaa
    27361 cccggcgccg cccaggagct gctggcccgg atcaccgagc cgtggggcga ccgtccgcgc
    27421 tcctggggac gcgtctggag cgcggagggc gaccggctca ccggccaggg actgcacctg
    27481 gaggcctccc gccactacgc catggcccgc ttcccgtacc ccggggacgc gccccgccag
    27541 gaagcccagc gccgctgcgt cgccgcgttc gacacctggc gggcggaaca gggcgcgggc
    27601 atcgagcggt tggaggtccc gctggaggac ggcaccgccg tctgctggac cgccgggctg
    27661 tcggccaccg acccgaaacc gctgatcgtc gtcatgggtg gcatcgtcag cgtcaaggag
    27721 cagtgggcgc cgctgctggt gcacgccgag gcgttcggtg tcgcgctcgc cgtcaccgaa
    27781 ctgcccggcg tgggcgagaa caccgtgccg tacgggccgc gttcgccccg gatgctctcc
    27841 gcgatccttg acgcgctctc gggccgggcc gatgtcagcc gcaccgccgc catcgcgctt
    27901 agcttcggcg gccatctcgc gctgcgctgc gccctggtgg actcccggct ggcctgcgtc
    27961 gccaccgtgg gcgccccgct gcggctcttc ttcgaggacg aggcctggca gcgccaggtg
    28021 ccccgcacca ccctcgccgc gctggcccac accaccggcg tcccgccgtc cctcgtcttc
    28081 gggtacaccc gcggctgggg cctcaccgac gaggagctcg gcgcgctgcg gatccccgtc
    28141 cactacatcg ccgcgctgcg cgacgagatc gtgccgctgg gcgaggccgc cgtgctccgc
    28201 agagcggccg tcccgggcga ggtgacggtc ctcgacgacg tgcacggcgc gcccgcccac
    28261 ctcgaccaca cccgcgggct gctgctgggg gccgcgctcg ccgccgccgc gccggcgacg
    28321 cccggcgcgg taccggaagc cgcctgatga ccctgaaccc ccgcggcgca accgccccgc
    28381 cggtcacgca caccgcctcg cggggccggc ccccgacccc gccgtcggcc cccgccacgg
    28441 cccgctggag cggcgctccg gccacctggg cgcaccgcca ccccgtcggg cgcgcggtga
    28501 gcctggcagt gggcctgggc gcgctgggcg gcgcggtggc gctgggcggg agacacgaca
    28561 aggtgctgtg gttctgcgcg gtggcgccgg acaccgccct gctgctcggc atcgccggag
    28621 cgcccacctg gcaccggatg ccgtcctacg cggtgcgccc gtacaacgtg ctgcactcgc
    28681 ccgcggtccc ggccgtcctg ctgacggcgg cggcgctcac cgggcgccgc cgcctcgccg
    28741 tcgcgggcct cgcctggctc gggcacatcg gctgggaccg cgcctgcggt tacggaccgc
    28801 gggacgcggc cggctacgtc accaggtgac cggcagcgcc gtcagccggt tcaccagcag
    28861 tccggtgtgc atcgtgatgt cctgctcggg aacggccagc cgcagcttcg gcagcgcgcg
    28921 cgccagcgtc gtcagagcga tctccagttc ggcgcgggcc agcggcgcgc ccaggcagtg
    28981 gtgcacaccg tgaccgaacg ccagatgcga cgggccgggc cggccggggc ggaagctgtc
    29041 cgcgtccggg aagacccgct cgtcgcggtt ggcggagcag atcgacgcga tgacggcgct
    29101 gttggcgggg atcggcacgc ccgcgacctc ggtgtcccgc agcgtcacgc gcagcgggcc
    29161 gccgtcgccc atcgggttgt agcggagcag ttcctccacc acggaggcgg gccggcgcag
    29221 cagcgccgcg aagccgtccg gctcgcgcag cagggtgaac gcgcaggtgc cgatcattcc
    29281 ggcggtcgtc tcgtgccccg cgaccagcag cgtcatcgcc atcgtgagga gttccagatg
    29341 actgaggctg ccgtgctcgt cgtgcgcctg caccagcgcg ctgagcagat cgtcgccggg
    29401 ctcgaggcgc ttggcgccga ccaggtccgc gagatacccc accagttcgt cgcggttggc
    29461 ccgcatcacc tcgggggagt gcgcggtgag cgacagcagc gcgtcggacc agccgcggaa
    29521 gcggtcccgg tcctcgtagg gcacccccag cagttcgcag atgacgaagg cgggcagcgg
    29581 gaacgcgtag gcgccgatga ggtcgacgcc ctcgcccgcg gtgatcatct cgtcgacgag
    29641 ccgctcggcg gcctgctcga tccgcggccg cagcgcgcgc acccggcccg cggtgaactc
    29701 ggcggtgacc agggcccgca gacgggtgtg ctcgggcggg tccagggtga acagaccgcc
    29761 ggcgtcgaac ggcatcgcgg tcagtttcgg cgcctcaggg aggacggtgg ccgctcggct
    29821 gaagtcggcg ccgccgagca cttcacggac atcctcgtag cggctcacca gatatcccgg
    29881 gtcgccactg ggcagggtga cccgggcgac cgggcagccc gcgcggagtt cctcgtaggc
    29941 cggtggcacc tgcgtcgcgg acggccgggg cggcgggtag gtggtcacag tgacactcct
    30001 cgggggcggt ggagcgccgg agcgcgcccc ggccgagcgt ccgccgccgg gctcgtgatc
    30061 cggtcgacgt cccgtcaagg agatccggtg gaaccggatc agaacttcca tgactcgtgc
    30121 tggagtcgtc cttgagcggc tgcggacacc atggacgcag cgccggacgg aggcgcggaa
    30181 tcccacggag gccttagatg agccagctcg ccaagtggtc tgtcacctac ttcctgggcc
    30241 cggtctaccg ggcgttggtg acctacggga cgttctacgt gcccatcacc ccgtacctct
    30301 acccgtcggg ccggaccgcg gggctgggac ggcagcagcg taagccgggc cacgactacg
    30361 cagacccgat cgccggctac gcgggccctg ccgacgggca cccggagacg gtccgtccgg
    30421 acgtcccgct gagtgccttc gaacgggaag ccgcccgcca gctgggcctt gtccacgagt
    30481 tcgaacgccc ctgaccactc aggttcaagg cgggtttgag gcgacgagct cattctgacc
    30541 ccgtacggcg acgccaacgg gggagcagcc ttgtctggac aagcggactt cgcagaatta
    30601 gtgcggcagc aagcgcaggc gcggaccggc caagaggcct tcgccttcac cggggaggga
    30661 cgcgacgggg ccgcgaccgt cgaccggatc acctacggcc gcctcgaccg ggaggcccgg
    30721 cggctgggcg cctggctgca ggaccacaac gcggccggta agcgggtgtt gatactccag
    30781 gaccagggtc cgctgttcat cgcctgcttc ctcggctgtc tgtacgccgg agcggtcgcg
    30841 gtgcccgccc cgccacccgg cggcacccgc cggcacatcg aacgcgtggc cggcatcgtg
    30901 aaggactccg ccgcgtcgtt cgccctcacc gactcccggc acgcgccggt catctcccag
    30961 ctgctggccg aggccggcca cggcgacgtg gtgtgcctgg cgaccgacgc gctgcccgcc
    31021 gacgccatcg cgccggccga cccggacgac tggcggcgcc cggacctctc gctggacgac
    31081 ctcgccttcc tgcagtacac ctcgggctcc accagcgagc ccaagggcgt gatgatctcg
    31141 caccgcaatc tgctcgccaa ccagcgggcg atccagcggg cgatgggcac cggggcccgg
    31201 tccaggatcg gcggctggct gcccttccac cacgacatgg gcctggtcgg ccatctgctg
    31261 cacccgctgt ggctgggcgc gcagggcgtg atcatgccgg cgatgagctt cgtacggcgt
    31321 ccggtgcgct ggctgcagat ggtctcggag tacgggatca ccaccggcgg gggccccaac
    31381 ttcgcctatg agctgtgcgt acagcgcgtc accgacgagc aggtcgccga actggacctc
    31441 tcccgctggg agaacgccgt caacggggcc gagccggtgc gggcggagac gctgtgcgcc
    31501 ttcgccgaga agttcaagcc cgccggtctc gacccttccg cgctctaccc ctgctacggc
    31561 atggcggagg cgacgctgct ggtgtccggc ggcatccccg gcagccgggc gccccaactg
    31621 ccggtggacg ccggcgcgct ggagcggcac cggctggagg accccatgcc cggccggtcc
    31681 gtccgcaccc tcgtcggctc cggtctggtc cgggacttcg acctgcggat cgtcgacccg
    31741 gagagcggcc gggtgaagat gcccggggcg ataggcgaga tctggatccg tggcgacagc
    31801 gtcgcccagg ggtactggaa ccggccggcg gagaccgcgt actcattcca ggcggtcacc
    31861 tcgaccggtg agagcggctt cctgcgcacc ggagacctcg gagtggtgcg ggacggcgag
    31921 ctgttcgtca ccggccggct gaaggacgtc atgatcgtcg ccgggcgcaa tctgtacccg
    31981 caggacgtgg agcgcaccgt gcagcgggtg agcgccctgt tcagctcgac ggtggtcttc
    32041 gccgtcgact ccgaccgcga gcatgtggtg gtcgtccagg aggtgaggtc agggcgcacc
    32101 ttcgacgcgg atctgcccgg cctggtgtcg gcggtccagc agagcgtgtc gcgggagttc
    32161 gcgatgccgg tgcggaacgt ggtgctggtc cggcccggga cggtccgccg gaccaccagc
    32221 ggaaagctgc aacgcgccgc catgcgccag ctgttcctca ccgaccggct ccgccccctg
    32281 cacgaggtcg tcgacccgga cctcaaacgt ctggtgcggc acgggtagga ccggctcagg
    32341 accgggccgg aggtcgtttc ctgcgaccat tggtatcggc cgttcacgta atctgctcat
    32401 ccgtatgcct aacgtggctg aatctgcgat cctgtgaccc ggaagttggc agttgggagc
    32461 cgggaggcgc gacgcatgat tcacgttctc ctcgcggagg acatgcacat ggtccgcggt
    32521 gcgctggtcg ccctgctgaa cctcgaggtc gacatcaagg tcatcgcgga ggtcgagtcc
    32581 ggggacgaga tcgtgcccac ctccgttcgg acacgccccg atgtggcagt gatcgacatc
    32641 gacctgccgg gcatcgacgg tctgaccgcc gccgcggacc tgcatgagca gatgccgtcg
    32701 tgccggacgt tgatcctcac gagcctcggc agacccggca acctccgccg ggccctggac
    32761 gcgcatgtct ccggtttcat cctcaaggac gcgccgccgg ccaaactggc ccaggcgatc
    32821 cgcagcgtgc gcgccggaga gcgggtgatc gactcccaac tggccctggc cgcctgggac
    32881 accggcgaga acccgctcac ccggcgggag gtcgaagtcc tccggctcac cgccaacggt
    32941 gcggaggcgg tggaaatagc cgcccggctg ttcctgtcgg tcggcacggt ccgcaactat
    33001 ctgacgacga ttctcgccaa gctcaacgcg cgtaacaagg tcgacgccat caggatcgcc
    33061 cgcgacgccg gttggctgta acggcccggc gtgagctcta cgccgccgcg ccactcagcg
    33121 gtaccagggc ggtcagccgg aaccagccgt cctcggcggc cgcggcgttg agcgtgccgc
    33181 ccagctcgcc gagtctcgta cagaggttgt cgaggcccct gccgtcgcgc cgggcggtga
    33241 cggacgggga ggtgttgagc ccgtcgttct ccacccgcag gcgcaccacg cccttgtcca
    33301 ggatcgcttc tatgacgcag ttctgcgcct tgctgtgccg cagcagattc gacaccccct
    33361 cacgcagcac ggtggagagc acggtgttga cccggtcctc gagcgggccg cagtcgacgg
    33421 tcacgacggt ggctatgtcg gccgagacca gcacggcccg ggtggcggct atctcggcgg
    33481 ccagcgacat gtcgcggtaa ctgctcgcca ccatgcggac gtcggacagt gcctggcggg
    33541 agatggccag catcgtcgag atctcctcac aggcgcgttc cgggtggctg ttgaccagcc
    33601 ggtagacgag ctcccccttg agggtgatcg cggagaggct gtagccgagc agatcgtgca
    33661 gatccctggc gacccggtcc cgctcccggg ccaccgccag ccgggcgagt tcggcgcggg
    33721 cggcctgtac ctccaccagc aggtctccca gccgggtgag gccgaagacg gagaggccga
    33781 tggtgccgac accacacgcg tagtagaagg cgctgaaccc gtcggacccg aggtgctgtt
    33841 cgatgaagaa catgctgatc gccacggccg acgcgctgag ccaggagact ttgccacgaa
    33901 ggaacaacag gagtgatccg gcgaagtagc ccggcatccc cacccagctg tccttcagga
    33961 tcaagaaggg gatataggtg agcagcccct gcatcgacag cgtccagatc cagtaacgag
    34021 gtctgtcacc gccccgattg gggagggaat ggaggttctg cagcaggaat agcgcaacga
    34081 gtatgccggc gccccatgcc atctccgaag tcggcacctg gcgggccagc atgctgacga
    34141 ttcccagcag cagatacccc agcatggtca aggccacgat cgcccggccg agccggggca
    34201 caggaatgtc gccccctgga aaatcgtgtt ctacctgccc ccgtacaccg accattacct
    34261 gtctcccctg cagcaatgga tcagcggtca tcgtgctgag caccaggccg tgccggaaga
    34321 ctactcgcta caggctgaac atgacctgct gttgccgcgc atcgttcgcc ccaatcactg
    34381 tcattgacgg ggtatcccat ggcactttct gcctccgcgg aggtgtcgtc cggtgccagc
    34441 gggccgagaa ggagctcgcc gatactggat tcctcgcgcc agtccagtcc gaaggcctgc
    34501 gccgacgttt cgatgtctcc gctgcccagc ggcaggggag cgagccgcat cgccgtggcg
    34561 accaagcaca tcgtctgctg gaccacgccc acatgcttga gcgcgagggc gtaccacata
    34621 ccgctgtact tccatgacaa cctgcggaag cgggcggtga tggtgatcag gacctgtggc
    34681 gtcgtggtca tacccgcggc ggcgctcgcc tgtgcgagca gttcggcagc ggagttcgac
    34741 gggtcgtcca gccgtaccag acagtggccg taggggtcgt aatagtaatt gccggccgcc
    34801 agtcccacgc agcggctgag agtgatgtag cactccagct cataggccga tccgccactc
    34861 ggataaggac ggctactggc gggataggag gcgggctcca gaccgatgct gctgtagagg
    34921 gaacggatgc gcgctatccg gtagaggaac tcacccagtt gccgatcact gagcggctcc
    34981 tccgcatagg tgcgggtgga ccggcgggtc tccagtaccg cggtcagcgg cgggtccgcc
    35041 gccagcaccg tgtcgagatc gggccggtac agcgggatgc gtacgccgtc gggcgcgctc
    35101 ttgaccgccg gttccgggga cagctgtccg agatagggga aagtggcccc gaagtcgccg
    35161 tcatggcggc cgagccgggt gcgggtgtgg aagagcagtt cgttcggggt ccaggtgatg
    35221 agcgagggat cgtggtcctc ggcgaagacc accaccccgt tcccgtcctg ttcgccgagc
    35281 gtgaccatgc cggcggcggc gaggtaggcg atgatgtccg ccaccacgcc ctccgccacc
    35341 ggcagcgcgg ccgttgccgc tttcagagtg gtcgccttgc cgagcacccc gatcacccag
    35401 gccgcctcgg gccggcggaa ctgcgcccgg tgcagggaca gcgccgagtc caggaccagc
    35461 agctcgtcct tggtctgcag tacggcgaac cgggagagtc tgatcggctg gtcgggcggc
    35521 accgcccgga tgtccagccg ggcgccgcgg gcgatcggga ccatgtccag gagttgcggt
    35581 tcggtgtcgt ccaggcccag cgagcggacg acgaggtagg agacgctgtc gaggagtgtg
    35641 agcaggcggg cccggtcgct cgcggtgatc tcgccgtgcg gccggggggt ggcgcgcagg
    35701 atgttctcca ggtccaccgg cccgaagctc atcctgcgca gcgattcgta gaccagctca
    35761 tcgggaccgg tcaggagcac gtccccccac cggctgtgca gcaccgcccc gccggcggag
    35821 gatgcccgtt ccagatggac gtcctcccgt agcgaccaca aggagaccct gcgcaggtcg
    35881 gtgcctacgt ccgggcgtgg ttctgaatgc acaggaggtc tccttcggat gcggtgttgc
    35941 ggacgcgatg tcagaggaag agaggaaccg gattgaggtt ctcgtacccc agcggcgtcg
    36001 tgcgacggcc gagcaggacc ggaacgtcga acaggcggcc cggtgcgaag cgggcccaga
    36061 agtggcgcag ccccggcacg atgaccttga cgaccggcag gccgatgtcg ggccgcgtct
    36121 gatcgaggac gagcagttcc attcccttgg cctccaccag acgctggatt cccatgacgt
    36181 cgtcgagcag gtccggatgg gcggtgtacg ggtagtcgtc cggggtggac atcggagcca
    36241 gcggatcagg cagcagatac ggttggttgg cgacggtggc ggtacggcac caatccagga
    36301 tgtcgttgcc cgaacactcg taacccccgc cgtccggtcg ggcgttcatg acaaagggca
    36361 gcatctggtc gagctcggtg agtgcccggc gcagcgcgac acgcatgtcg aagtgggcgc
    36421 cgagcccgat cacgatgtcc tcgtcctcct tgtccgtacg ccgggacagg gccgcaaccg
    36481 cggggatgcc gaagtcggcg gtcaggtcca gggcccacag ctcgcggttc cggcccgcgt
    36541 acagggagcg ccgctcggcg atccagggct cctcgaacgc gctgagactg agccccggat
    36601 ggcgggtgcg gttgtaccac cacagggccg tcgaatcgcg ctccacgagt tcgaggaagc
    36661 cctgcacgat ggcgtcctcc aggctgcttc cggccgcaca cccgttggag tcggccgagc
    36721 agaagccgcc ggaggattcg ggggtgttgt agtacagcat gctggtcggc agcagccgct
    36781 gccgctgctc ggtgagcgac cagaccggtg tccagtccac gtcggcggtg acgtcgaact
    36841 cctcgttcac ctgttggaag tccccgtgcg cagcgttcca gcggtcccgg tccgcgtact
    36901 ggcgctcgtc gaagagctgg cagcggttcg ggtggatggc cggctcgccg aggttccgca
    36961 gcgaatcgcg tacgcgcagt tcctcgccgg tgaacacacc ggagaacctc tcgagcgcct
    37021 cgcacagcgc cccgacctcg gcctccaccg aggtcacacc tttgccggcg ctcataccgc
    37081 ggaagccgtg ccgcaaggag cgcagccccg gcgtccccag cgccatgttg tggcccgccc
    37141 ggtacacctg gagtccgggt ggcgcggccg ggtcggggtc gagccggctc accaccccgg
    37201 tcagcgggct gacctgcgtc cggtagcggg ccaggacgtt ctcgggagag gcggaccggt
    37261 cgccgctgcc gttcgcgtac gccttggaac gcgaacgcaa cggcagcgga cgtccgatcc
    37321 gttcggtact gagagaggga tccccgcaga aggcgcactg cgggcggcgc tgtaccgcgt
    37381 gatgacgggc cgtcatcgtg aagttgtcca gggtcagtac ggactgctgc ccgtggtagc
    37441 ggtgcccggc catccatttc gccgcttcga gagccaccat gtgcagtccc accccctggc
    37501 tcgggggtat ggaggcctgc ggaatcagca gtggaccgga acgccccaac gtgcgctgga
    37561 cgtgattctc cacttcccgg tgaccgcgca gtcggtgggc gaggcagttc cagcacgggc
    37621 cctcacccgg ctggaacacg gggccgagcc agatgtcggc cccgtgcggc ttcgccagca
    37681 gccacggccg tccggccgcg cgatgcgatg cgtcgaccgc ggccagttcg ctggccaggt
    37741 agtcgtcgca gaccacgacg gacaggtcgg cgcccgggat tccgcagctg gaccccgtca
    37801 ccgcggaggt ggcgtggacc gacaccccgg tggcctgcag cgcggccctt accgcgctgc
    37861 cgtcgaccgc gccgaccgtg agaatgcgaa ccgatccgtc cgccagccgg gccgcggtct
    37921 gcgcgccgtc gagcccggcc agttcccaga acgcgagccc cgtcctggcc gggttctcca
    37981 acgtgcgtgc ggtacgccgg aagtcgacca gtgcggcatt ggcgagttgg gccagtacgt
    38041 atccgatttg ctccggggcg agttcccgtc cggcgtcccg gattatctcg ttgattcccc
    38101 ggcggccgtc catgagcgga gccatgagct ccaactgcgg acagtcgatc atcttcacgt
    38161 cccgctcgga gaagagatat gtcccctcgc ccggtattac ctcagcgcgc agatgagcct
    38221 tgaactccgt catagcagca tccccctgtg ccggcacggt tttagtggat catcccttgg
    38281 cgcagaaaca actgacggag ccgcgtgcct tcatctctcc cgtgaagtcc tcgatcacca
    38341 gcgccagttg cggtgccggc gggagggcgg gggtgctgac gtcgccggcg acgtgcaagc
    38401 cgaactcggc gagtacctgg gaggggttct gtgcgtaccg gaggcttaag gccggctcga
    38461 tccaactgag cgccaccagc tccgcgaagc gccagtcctg ctctattgcg tccattctcg
    38521 ttctccagtt ctgtgacctg ttcatggccg gttgatgcgt tcctggcggt acaccgagga
    38581 gtgtgcggct gaaaatcggg cagcgaacag tgggtcggtc atggaactca tgtgaagatt
    38641 tcatgatctc ggaatcccgc cctcccctga aacccgtgaa gatctcactg ttcaggtcaa
    38701 tgccctcgat gggaaccttt gctcgtgctc ctatgtgcgc agcgatcgcc gggtcgagac
    38761 gacacaacgg cggcgtggaa cggggagagg acggcaccga tggagatcaa cgtcttggga
    38821 ccattgacgg cgagcgaagc cggcacttcg attgtgccga gcgccgccaa gccgcggcag
    38881 atcctggccg ttctcgctct gaacgccaac catgtcgtga ctgtcgccag gttgatggag
    38941 gagctgtggg gttccgatct gccgcgcagt gctccgacga cgctgcagac gtacattctg
    39001 cagctccgcc ggaaactgag cgcggcgctg gggtcggtca ccggagcgaa ggacgtgctg
    39061 gccacccggc acagcggcta tcagctgagc atggactccg cggccatcga cgcctggcag
    39121 ttcgaccagc tgacggtggc gggatacgcg gcctacgagg ccggggacgt cgcccgggcc
    39181 tcccgccggc tgagcgatgc gctgaacctg tggcgggggc cggcgctggt cgacctgcag
    39241 cacggaacgc tgctcgaggt cgaggtcatg cggctgaggg aaagccgcct cgcggcgctg
    39301 gagcgccggc tcgacgccga cctggccatg cgccggcatc atgagttgct cggcgaactg
    39361 gccggtctga ccgcggaatt cccgctgcac gagaacctgc acgcacaatt catgctggcg
    39421 ctctaccggt gcggccgccc ttcgcaggcg ctcgaggcat ttcgccggct gcggtccggt
    39481 ctcgtggacg agctggggct cgagccttcc gcccgggtgc agcgcctgca acgggcgatt
    39541 ctctccgcgg acccggtact cgacggggtt caccccggcg cggtggtcgg agtggcgagt
    39601 atcggctgag gcccggccgg ctgctccagc ctgcgtccag tgaccttcca ggcggcctgt
    39661 ggacgatcgc ggcatccgtc cggatgcggg cggaacaagt ccaggaggcg gtcggctgtg
    39721 ggtggatatc tggcggtgag accaaaaatg gccgccaggc ttcggctttt ctgctttcac
    39781 cacgcgggtg gcggcgcaat gtcgttcgct cgatggcaga atcgtttcgg ctctgacatt
    39841 tccgttatcc cggtacggct ccccggacgt gagacgcgat tgcgtgaaga gcgcgtcacc
    39901 gatggagaac agttgtcgcg cgaactggaa gccgagctgg ggccctttct cgaccgaccg
    39961 tacgccctct acgggcacag tctcggcgcc ctggtcgcct actccttcgc cctccaccac
    40021 cacaggtcgg gaggacgtcc gcccgaggtg ctgacggtcg gagcctgctc cgcaccgcac
    40081 ttggggatgc cggacctgga gggtgcggaa gggtccgacg aacgggtgct ctcggtgatg
    40141 agggcgtccg gcggcatcac cagccagctg ctggaccggc cgcagtggct gcaactcacg
    40201 atggcgatca tgcgggacga tctgctgctc gccgccggcc tgcgggccgc ggcgggagac
    40261 ccgctcccgt gcccggtgct ggccgtgtcc ggccaggacg acctgctggt accgccgggt
    40321 gcggtacatg cctggtcccg ctacgcgccc gagggtttcc ggacgggctc ggtgcccggg
    40381 gaccacttgt tcgtaaggga cgccgacctg gccgatctgc tgcgcgccga gctcgaagag
    40441 cggcgtccgc tggaaccggc catctgaccc tcgagaggag ccgagaagat ggacattggt
    40501 gtgcttggcc cctgccgggt gacgcaggcg ggacaatcag tcgtcccgac tgcgatcaag
    40561 ccccgcaagg tgctcgccct gctcgccctg cagccggacc gggtggtctc ggtgagttcg
    40621 ctgatcgagg agttgtgggg cggcaatccg ccgcgcagcg tgcagaccac cctgcagacg
    40681 tacatcctgc agatccggaa cctgatcacc aggtcactgg ccggtgagga ccagcgcgat
    40741 ctgccgctgg gagccaagag cgtcctggtc accgaggcgg gaggctacct gctagacacc
    40801 cagggcggtg tggtggactc cgtggagtac gagcggctgg cgggtgccgg ccaccgggcc
    40861 ctggagtccg gcgaccactc cggggcagcg ctgctgttcc agcaggcgct cgcactgtgg
    40921 cgcggcccgg cgctcgtgga cgtgcaggtc ggcccgttgc tggaggcgga ggtgactcgg
    40981 ctggaggaat cgcggatgag catcctcagc cagcgcatcg aggccgatct gcagctcggc
    41041 cggcaccacg agattctggg cgaactggcc gggctggctg cccagcaccc cacgcacgag
    41101 aggttgcagg gccagctgat gctcgccctg taccgggccg gccgccgggg cggcgccctt
    41161 gaggcctacc accgcatgcg cgtggtgctc ggcagggagc tgggactcga cccgtccgcg
    41221 gcgttgcagg aactgcagca ggcgatgctc gcgtcggacc cgggactcga atgcgacccg
    41281 gtcggttcgc tgaccggcgg gggaccgctg cgagtggtgc gcgccggctg accggcacag
    41341 tgacagggcg ggccggcgcg tggatcagga ttcgcgggcc gagatctggg tcaggcaggt
    41401 gagcaggctc cggttgaagg tggcgatgaa accctccggc gtaccggtgt cgcggggccg
    41461 tgagagatac ggggcgagct tgcgctccac ctcctggacg ccgggctggg aggccatgaa
    41521 gcgggccacg tcctggaggt cgccttcgta ctcgatgacc cggaccatcg tggcgtccct
    41581 gatgaagaca gcggtggcga ggatccgggt cgtctccgcg ccgtcggcgc cctcgacgac
    41641 gggggagccc acccgacgga atccgccgaa gatctccccg atctccttct cataaccggc
    41701 cttgatgtcg taggtgatgg cggcgaacgg catgggcggc ctccgaaggc ggcaaggggg
    41761 tcggcggacc tgctcggtcc cgccgatgcg ggccgggaac ggccccggca cctatcgtca
    41821 ccctcgcgct ctcgcggcac tggagcgctg ctcggccccc gcacgagacg ttcgcgcgag
    41881 ggccgggccg acttgggtga tcgtggctat gtgccggctg cgtcctgcgc cccgggatgc
    41941 gagggggcag gaggccgggg ggcggacagt cgtacgtcga tgagactgag cccgtaccgt
    42001 tcgaccgcgt cccgcagatc cgcggtggtc ggcgggcggt ccgggtggat cgtgaggtcg
    42061 agccggcgct gcgcggcggg accgtagagg cggatcagcc ggagatagcc gttcgcgatc
    42121 cggaccgggt ccgtcaccag atccaggcgg gcgggccggc ggtccccctg ccaggtgatc
    42181 tcggcatccc caccccccgc gaagttgtgc cgccagttgc ccgaagtggc cagcaccaga
    42241 tcctcgtcga gggtgtgcgc gcccaccggg atggtgaacg cccgccccgt gcgccggccg
    42301 gtgaagtgca gcagcagcaa ccgctgcgcc atgggtcccg gagcaggcgc ggacagcgcg
    42361 gcgatcacgg ccgcgttgtc aggcaggccc tcgtcgccag gccgtcccag ttcgatcagg
    42421 ggccgcgcgg tggggctcat cggagcactg ccacggccga ggcggtcagg atcagggcca
    42481 cgatcgcgaa cgcggtacgc aacgcatgcc agttgcgcca ctgctggcgc gggtcctgcc
    42541 agtcggggct gaggttgttc tcgtcctggc tcttcacccg gttgttgatc ggcacgttcc
    42601 gggtctggga gacaacggcg acacccacca tgaaagcgcc cgccacggcg aacagcggcc
    42661 ggctcgcggt ggactcggtc cggaaggccg cgaagacgtc gacgaccacg gaggtcatga
    42721 cgaggtacgg catgatgtgg tcgtagcggc ggccgagaag cctgtgcgtc gtgatgtacc
    42781 ggtccgcagg catcgcgatc aacgcgggca tgacactgat cgccacggcg aacagcactc
    42841 cggcgacgat gccggtgccc aggatcacgg cgacgctcag cacttgcagc aacaccatgc
    42901 tcatccctct ctcgactgtg ggtccacggt cagttcgcgg caacgtcgca gggatctctc
    42961 ggcgggtact ggaagaccgg tcgaatccgg gacgcggccg cgggccgggc tccgcagcac
    43021 cacggcgccg ggggagcgct cgcgaccgcc ccggcccact ccggctcaag tccttctgga
    43081 ggaagggtgg tcacgctgcc gtccgggtcc ttcagcgggc tcacgacagt gaggagagga
    43141 aaccggatga gtgatttcac tctgcaggag ctgaccgcga agctgcgcga gtgcgcgggc
    43201 gagcccgacg gtgtcgacct cgacggagac gtccaggaca cccccttcat ggaactcgga
    43261 tacgactcgc tcgcgctgct ccaggtgacc ggtgtcatca agcgggagcg caggatcgac
    43321 ctttcggacg acgccgtggt cgaggcggaa acaccgcgca tcctgctgaa gatgatcaat
    43381 accagcctgg cgcaacccag ctgaccagca cagcacggcc gtcccgccgg gcgaccggtc
    43441 gctgtcgaga tcgaattctg tgggaggaat cggatgccgt acggagcgat catgtaccgg
    43501 gtgaagcccg gtcacgagga tgagatcgcc aagatcttcg agaatttcaa ccgggtggac
    43561 accgcggacc tgcggtccga cgacggtcag cagaccggtc gcattctcgg gaccggactc
    43621 ttcatcaagg acgatgtgat ggtccgggtc atccactacg agggtgatct ggctgccgtg
    43681 ggcaagcaca tggccaccca accgggcgtg catgcggccg aggcccggtt ggctccctat
    43741 ctgcaggagg agcgggacac atcgtccccg cgggcgttcg gcgagtactt ccggaatgcc
    43801 tccatgcgca gcctcctcca actcgacgtg gaaacgctgg agaccaaggc gtgaccgcac
    43861 cctgacgggg tcgtctcccg gagctccgtg cgatcgggcc gatcgcacgg agctccggcg
    43921 cgtccccggc cggccgcccg gcccaccggc tccgacgcgc tccgatgcgc gatgcagtcc
    43981 gattcgagca ggtctttaga gccagctgtg acggttccgg ctgatggttc gaggaactcg
    44041 tatgaaggag gtcgacggtg caccggacat taatcgtggc gaagatgcag ccgggtaagg
    44101 cagacgacat cgcgaagatc ttcgctgagt cggatgcgtc ggatctgccg cacatgatcg
    44161 gcgtgtcgcg acggaccctc ttcgctttcc acgatctgta ctttcacctg gtcgaggcgg
    44221 acgaggacat caccgacggc ctctaccggg cgcgcagcca cccgctctac gacgacatca
    44281 accgcaagct cgcggagtgc gtgtcaccgt acgacccgaa ctggaaagag cccaaggacg
    44341 ccatggccgt gcccttctac gtgtggactc cggagcaggg gaggatccaa tgaccacgca
    44401 gcagcctgtg cgcatctcgg cgaacgaggt cgcgtccaac cgcaagcgcg gtggcgacat
    44461 ccgggtaacg ctcagtccgg tgactgcggg ctcgacctcg ggcttcggcg gagtgatgta
    44521 cctggacccg tcggagttcg tgaccgagca ctaccacccg tactccgagg agttcatcca
    44581 cgtcatcgcc ggagaactgg agatgacgct cgacggtgaa ccgctcaaac tcggcccggg
    44641 ggactccctg ctggtgccga tcggtgtacg ccaccggctg gtcaacatcg gtgaggtcca
    44701 ggcgcactgt gccttccacc tctccccgtt ggcaccccgg cccgacctcg gccatgtgga
    44761 caccgagaag ccgaccaacc cccaggcgcc caacccgaac gtgggcgggg ccccgtgagc
    44821 cgtcgcgcgg tggtcaccgg gatcggtgtc ctggcaccag gaagcctggg ccgagagggc
    44881 ttctgggatc agctctccgc cggccgcacc gccacccggc gcatcaccct cttcgatccc
    44941 gcgccgttcc gctcccaggt ggccgcggaa gtcgacttcg atccggccgc cgccggtctg
    45001 actccccagc agatccgccg gatggaccgt gccgcgcagt tcgccgtggt gtgcgcacgc
    45061 gaggcgctcg cggacagcgg agccgaactc gccgcgctcc cgccggagcg gatcgcggtg
    45121 tccatcggca gcgcggtcgg ctgcaccatg ggcctggagg aggagtacgt caccctcagc
    45181 gacggcggca agaactggct cgtcgacagc agttacgggg taccgcacct ctacggctac
    45241 atggtgccca gcaccctggc ggtggaggtc gcccacgcgg tgggagccga gggccccgtg
    45301 tccctggtct ccaccggctg cacctcgggt ctggactcca tcggacatgg agtgcagctg
    45361 atcgaggagg gttccgccga catcgtactg gcgggcgcca ccgacgcccc gctctccccg
    45421 atcaccgccg cctgcttcga cgcgatcaag gcgaccacgc cgaacaacgc cgacccggaa
    45481 cacgcctcgc ggccgttcga ccgggaccgc gacggcttcg tcctggccga gggctcggcg
    45541 gtcctcatcc tggaggagaa gtcggccgcg gaagctcgcg gcgcccgcat ctacggggag
    45601 ttcgtcgggt tcgccggacg cagcaacgcc ttccacatga ccggtctcaa ggccgagggc
    45661 cgggagatgg cggaggccat cagggccgcc ctcgaccagg cgaaactcga cccgaccgcc
    45721 gtcggctaca tcaacgccca cggctcgggc accaaacaga acgaccggca cgagaccgcc
    45781 gcgttcaagc ggagcctggg cgaccacgcc taccacgtgc cggtcagctc catcaagtcc
    45841 atggtcggcc actcgctggg agcgatcggt tccatcgagg tcgcggcctg cgcgctggcc
    45901 ctggaccgcc aggtggtccc gcccaccgcc aacctgaaga accccgacgc cgagtgcgac
    45961 ctggactacg tgccggtcac cgcccgggac cacgccatgg atgtggtgct cagcgtgggc
    46021 agcggattcg gcggcttcca gagcgcgatg gtgctggcca ggcccggcgc tgtcccgtat
    46081 gagaggagct gacggtgagc agcgcgacga acggatcgtc ggccgccccg gtgatcaccg
    46141 gtctgggagt caccgcgccg acgggtctga cggcggacga gcactgggcg gcggtcctgg
    46201 ccgggaagcc ggccatcggc cggatcaccc gtttcgaccc gtccagctat ccggtccaac
    46261 tcgccggaga ggtagcggac ttcgacacca aggccagggt gcccagccgg ctgatccacc
    46321 agacggaccg ctggacccac ctgggtctgt ccgccgccgc cgaggcgctg gaggatgccg
    46381 aggtggtgcc ggccgaactg cccgagttcg agatggccgt ggtcaccgcg gcttcctccg
    46441 gcggcaccga gttcggccag cacgagatgg agaacctgta ccagcacgac ccgtcctggg
    46501 tcggtgccta ccagtcgatc gcctggttct acgcggcgtc caccggtcag atctccatcc
    46561 ggcacggcat gcgcggaccc tgcggtgtgc tctgctgcga gcaggccggc gggctggacg
    46621 cgatcgggca gagccgtcgg ctgctgcgtg gcagctcccg gctggtcgtg accggcggaa
    46681 cggacgcctc gctgtgtccg tacggtctga ccgcccagtt gagcaccggg aacctgtcca
    46741 ccgtcagcga cccgggacgg gcctacctgc cgttcgacac cgcggccagc ggctatgtgc
    46801 ccggtgaggg tggcgcgatg ctgatcctgg aacgggccgc ggacgcggag gctcgcggcg
    46861 ccggcggcta cgcccgggtg ctcggttacg cggcggggtt cgacccggcg cccggatccg
    46921 agcgcccgcc ggcgctgcgc cgcactctgg aggcggccct cgcggacgcc ggagtgacac
    46981 ccgccggggt cgacgtggtc ttcgcggacg cgtcgggtgt tcccgcacag gacgcggcgg
    47041 aagccgcggc gatccgggcc gttttcgggc cgggcagcgt gccggtcacg gctcccaaga
    47101 cgctgaccgg acggctctac ggcggtggtg cggccctcga cgtggcgacc gccgcgctgg
    47161 ccctgcgtga ccaggtgatc ccgcacaccg tcggacccga gtcaccggtt cccgggtacg
    47221 gcctggatct ggtgctcggc gaaccacggg ccgccgcgct gcgcaccgta ctggtcctgg
    47281 cccggggaca cggcggtttc aacgcggcct tggtactggg acgtccggct tcctgacagc
    47341 ggagcgggac gaaggcgaga gacaagggag agtggcgatg gccgggcaca ccgacaacga
    47401 gatagtgatc aacgcaccga tcgacgaggt ctgggagacc accaacgacg tggtcaactg
    47461 gccggatctg ttcagcgagt acgccaaggc cgagatcctg gaacaggacg ggcagaccgt
    47521 gacgttccgg ctgaccatgc acccggacga cgaaggccgg gtgtggagct gggtgtcgga
    47581 gcgcaccccc gacccggtga cccgcacggt gcgcgcgcac cgggtggaga ccgggccgtt
    47641 cgagttcatg aacatctact gggagtacac cgagacaccc gaaggcgtgc ggatgcgctg
    47701 ggtgcaggac ttccacatga agccgcaggc acccgcggac gatgccggca tgaccgaaca
    47761 cctgaatcgg aacactgcca tccagatgaa gctcatcaag gacaaggtcg aggccgcttc
    47821 cctccggaag tagccgcgga cgtacccccg gaggtcaccg gtgcccgctc tcctcatccc
    47881 tctcgtgctg ctgatgaacg ggctcgcggc cggatgcatg ctcggtacgc tgctcggcgg
    47941 ctggccactg ctcgcgggtc tgcccgacga cggctacgtc cggacccacg cgttcttctc
    48001 cggccgctac gacccgtaca tgcccatctg cacgctgggc accctgctgg gcgacagcgt
    48061 tctcgccgcc ggtgtgggtg acggctgggc cagggcctgc ttcaccgccg cggcactgct
    48121 cgcgctctgc accgtggtca tctccttcgc caagaacgtc cccgtcaacc ggtggatccg
    48181 caccgtggac ccggacaacc tgcctaccgg cttcgacgcc acggagcgcc gcagccagtg
    48241 gggcctgtgg aacaagcggc gcagcgtgat caccatgctc gccctgctgt ccaactgcgc
    48301 ggcgctggcc acgcttcttt gaggaggaac agatggatct cgaactgcaa ggaaagaagg
    48361 cgctggtcac cggcggcacc cgtggtgtcg gacgcggcat agtgctcgca ctggcccgcg
    48421 ccggcgtcga tgtcatcacc tgctacctac aggaagggga gcgggtcgcc accctggagc
    48481 gcgagctcaa ggagatcggc ggcgaccacc acgtgctgcg cgccgacctg agtgaccccg
    48541 cgcaggtcgc gagcctgctg gagcaggcgg gcagcctgta cggccacctc gacctggtgg
    48601 tcaacaacgc gggcaccatc agccacatcc cctacgcgaa gctcccgttc gaggaatggc
    48661 agcgcatcgt cgccaccaac ctcaccgcca cccacctggt gacgcagaac gccctgccgc
    48721 tactgggcga gggctcctcc gtcgtgagca tcggatccaa gggcgcggag gcggggatcc
    48781 cgctgcgggc gcactacacg gcgacgaagt cggcactggt cgggctcacc cgctcgctcg
    48841 ccaaggagct gggctcccag ggtatccgga tcaacgtggt cgccctcggc gtcatcgaga
    48901 ccgaggcgct ctacgacctg ccgcaggagc agcaggacct gatggtccag cgctacagca
    48961 gcaagaccgc gctcggccgg ctcggccgga ccgacgaggt cgccggcgcc atcctgtggc
    49021 tcgccagtga cctgtcccgc tacgtcaccg gtgccaccat ctcggtcgac gggggaatct
    49081 cctgatggcc ggcggagcct tccgggtgat gctggaaatg acgatcaagc ccggtctgtc
    49141 ggcggagttc gagcaggagt ggcgcagtgg taccgacgcg gtcaccggcc accccgcgaa
    49201 catcggccag tggctggctc gcagcaccgc cgacgaggac acctactaca tcgtcagcga
    49261 ctgggtcgac gagacgggct tccgggcgtt cgaggacggc aaggcgcacg tcgcccatcg
    49321 cgagcgactg cacgcctacc gcgcctcggc gaccttcgac accatgcggg tggtcgagca
    49381 catccaggga gccgcccatg ccgcctgagg cgggcgaggt cctggtgatg atccatcacc
    49441 aggcccggga cgaggccgag ctggccgcgg tgcgcgaggc gtaccacgtg gtcagccggc
    49501 ggctcgccga cgtgccggga atgctcgcca atgagttgct gcagtccgcc ctcgacccct
    49561 cggccctgac cgtggtgagc cggtgggcgg atctcgcggc cttccagtca tgggaagagg
    49621 gcgccgggca ccgcgcggac accgctccgc tgcggccgta ccgcgacaca cgactctccg
    49681 ctccgttcgg tatctaccgg gtcgacgcgg cgtactgaag gaggagcaga tggagcaggg
    49741 actggccggc aaacgcgtac tgatcaccgg cggtacgcgc ggcatcggaa gggcggcggc
    49801 actggccttc gcgcgcgccg gcgctcgcgt cgtggtggtg tcgcgcagcg cgggggagga
    49861 cggcgagtca ctcgcccgcg agttgaagga gaccggtgac ggacatctgc tgctgcgcgc
    49921 ggacgtgacc gacgccgccg acgtccgtac ggtggccgca caggtgaggg aggccgtcgg
    49981 ggggctcgac gttctcgtga acaatgtcgg agtggacggc caggtctggt tcgcggagct
    50041 gcccgagtcc gaatggcacc gggttttcga ccacaacgtc acctcggcct acctgatgac
    50101 ccaggccgcg ctcgacctgc tcgtcgacgg tgcctcggtg gtgaacatcg gatcctcggt
    50161 ggcgctgcgc ggccgggtcc gcggagtgca ctacaccgcc tccaaagccg cgctgatcgg
    50221 gctcacccgc gcgctgtgca aggaactcgg gcctcgttcg atccgcgtga acaccatcgc
    50281 gccgggtctc accgagaccg aaccgggcgc cggtctgccg ccggaggccg tggagcggat
    50341 cgtcgggatg accgcgctcg gccggatctg cactccgcag gacgtggcgg gcgccgtgct
    50401 ctttctggcc ggcgacacct cccgctacat ctcgggcgcc acgctcaatg tcgacggcgg
    50461 ggtctgaccg tggacatcgg actcgggctg cccaccaccg ttcccgacaa gtccgggcct
    50521 ggactggccg cctgggcgcg tgcggccgag gactcaggtt tcaccactct gggcgtgctg
    50581 gaccggctgg tgtatgacaa cttcgaaccg ttgatgtcgc tggcggtggc ggccgcggtc
    50641 accacccgca tcaagctggc cagcaccatt ctcatagccg gctatcgcgg tggggcggcg
    50701 ctgctcgcca agcagacggc gaccctcgac gcggtctccg gggggcggtt cacgctcggt
    50761 gtcgccgccg gaggccgtga cgacgactac aaggccaccg gcgccgacta cgccggtcgg
    50821 ggggcgcggc tggacgaact cctcggtgaa ctccgcgaca tctggagcgg ggagggtccg
    50881 gggcccgtca tcggtccgct ccccgccggg cagggcggta tcccgctgct ggtcggaggc
    50941 cattcccgga ccgcgatgag gcgttcggcg agattcggca ccggctggat cgcgggcggc
    51001 agctcggcca cggcctacgg ggaactggtc cgccaggcac agcacgaatg gacgctggcc
    51061 gggcgcaccg aacggcccag gatggtctcg ctggtgtatg cgtgcctcgg cccggacgcc
    51121 ggatcgacgg cgggccgcta tctgcgcgac tactactcgt tcatcggcgt gaaggccgaa
    51181 cgggccgcca gcggcgtgct cgtggacgcg gcgcagatcc gtgacgcggc ccaggcgtac
    51241 gcggaggccg gttgtgacga gctgatcctg ctgccgtgca ccgcggactc ccagcaggtg
    51301 agtctgctcg cgaaggcggc cctgtagccc cttttcaggg acttcgcaca caagattccg
    51361 gcccggactc gtaccatgag tccgggccgg gatcttgtgt gcgtgttggc ctgcgggtgg
    51421 ggccgcgggg cggtggagtg ccggaggcgc ccgtcacgtc aggtgtgacg ggcgcctccg
    51481 gcggctgtgg gacggagctg tgttacccga ggccggcggc ccgggagagg acctcggtca
    51541 gcacctgctg cgggtccgcc accggcccct gcgagcgcca tgcgacgaac gcgtccgggc
    51601 ggaccagtac cgcgccaccc gggcccacgc cgtacaccga accccagtcg cgctcctcgc
    51661 ccggtgtcag ctcggcgcca gggcccacca ggtgggccct gagcggcaca ccgagctctg
    51721 cggcggcctt caccgcggac tcggcccacg cggcgccgga ggcgtccgtg aggagcacgt
    51781 aggagtccca gaacaggtcg atggtggaga gcttcgaacc gttccgctcc acccataggt
    51841 gcggcgccct ggtgccgggc tcgcccttca gttccaggtg cggagtgagc accggaccgg
    51901 tctggtcgtg agtgatggcc tccgacttgt accggtaccc gagggtgatg atgatgtcgt
    51961 ccaccatcgt cgcccggtcc tcgtcggtgg cgtagccgtg ccggatgcgg ttgcgcacca
    52021 tggcctgctc ggccatggcg gagccgaccg cgtgccgctc ctcgtggtag ctgtccagca
    52081 ggacgtcccc ggcccagccc ttgatgacgg cggccagttt ccacgacagg ttgtgcgcgt
    52141 cgtggatgcc ggtgttggct ccgaacccgc cggcaggcgg gtgcagatgg gcggcgtccc
    52201 cggccaggaa gatccgtccg gtcctgaacc gctcggcgac cagctgggcg ccctgccagg
    52261 gaaccttggc gacgatctcc acgtccatgt cgggacggcc ggaaccggtc ctgacgatgt
    52321 cgatgcagcg ctcgtcggtg aagtcctcgg gcttctcgcc cttgtccggg aagtagatcg
    52381 gggcggccag gaaggggtcg cagccgtgca gccgggacag gcccatcaga gtcccgttga
    52441 cattggcgta gcacaggatg aacgggcggt gcttgatcag tgattccagc tccggagcct
    52501 tgaagtagat gctcagagcg tcgaacaccg ttccgcggcc gctgcgttcc acgcccagct
    52561 cggtccgcac atggctgttg gcgccgtccg cgccgaccag gtagccggcc ctgatggtgt
    52621 agcgccgacc ggtctccagc tcctcggcga cggccgtcac gccctcgtcg tcctgggtga
    52681 actcgatcag cttggttccg aacctgatgt cggcaccgaa ctcccgggcc ttgtcgacca
    52741 ggacccgctc gtagcggtcc tggccgcagc ccatcacgcg ttcggggctg acggtgggtc
    52801 cgtccagtga gggcgactcg aggacgacgg cgttgtcgat gtcggcgaag gtgtcgacct
    52861 ggatgatccc gccctcgaag aaggggtgcg agtctcccat ctccagggcc cggatgtcct
    52921 tgccgattcc ggcggcacgg aacaactcca gggtgcgcga ctgcaggccg ggggcccgcg
    52981 gcagcgtgga ggtcgccgtg cgcttttcca gcagaagagt actgatcccg tggcgcccgc
    53041 tgaacagggc ggtggacagc ccgaccggtc cggcaccgac gatcagtaca gggatgttca
    53101 cgtcatacat gcgtatcccc tcaggaacac tgccatgcgg actgtccgcg gcacaggtaa
    53161 ggggtactga ccggtgctca aggatgcctg gcctcccggt cgggtccgtt ggcccgcctg
    53221 cggttcgagg cgtgttcgag gtcagctcca cggccggctg cgagcgtcac gacgatgaca
    53281 ccggcgcctg gtggccaggc gtccaggaag gagtccgccc gatgacgacc acccccccgg
    53341 acgtcagtac ggccgccggg atcctccggc tcggcaacgc gttctgcgat gccaaggccc
    53401 tgctgaccgc cgtggaactc gatctgttca cgcaactgca ggaggccccg tccggcgggg
    53461 cgaccgccga ggagatcaag gggctgctgt cactgcacgg ccggggcctc agcgactttc
    53521 tcgatctgct ggtggccctg aaggtgctgc agcgcaccga cggcgtctac cgcaacgcgc
    53581 cgggtacggc caagcacctg gtccgcaccg gggacgccta tgtgggtggc ttcctgctgc
    53641 ggtccagccg caacctctac ccggcctggg gtcggctgga ggaggcgctg cgcaccggca
    53701 agcagcagtc gggcagccac tacgacgaag tcacgcaaaa ccccgcgatc ctgcgccagt
    53761 tcatcggcag catggatgcc ttcaccaacg ttctcggtgc ccagctgatc gaggcgttcg
    53821 actggtccgg attcacgtcc gtactggacg tcggtggcgc ccggggcaat ctgtgctccc
    53881 agatcgtcaa ggcccagccg catctggccg ggcatgtctt cgatcttccg gagatggcgc
    53941 ccttcgcgaa ggaactcgcg gaggaactcg gcatccccgg caaggtggag ttccacggcg
    54001 gcagcttctt cagcgacccg ctgccgcagg ctgagatcgt ggtcatgggc catgtcctgc
    54061 acgactggga ccccagccag cgcagctacc tcatccacaa ggcgtacgac gctgtactgc
    54121 ccggtggaac gctgctcgtc tacgaccgga tgctcgacga cgagccggag cacgccgaga
    54181 acctggtgat cagcctcgac atgctgctgg tcaccgacgg cggttccgaa tacccggccg
    54241 cggagatcgt cggatacgcg gagcacgccg gcttcgccgg caccgaggtc aagctgctcg
    54301 gcgactacga cacgctcgtt gtcgcccgta aggccgcctg agcaccgcca ctgccgtaca
    54361 cagcactccg cccccggtcc tggaagagga ccgggggcgg agtgctgtgt acggggctgt
    54421 gtcagctcgc cggctcgggc tccggctgct tgtccgcgac cccggcgcgg gaccgcggga
    54481 tctgcgtgcc gaacacgcgg cgggacggcc accaggtgcg gtcgtccagc tgcagcgcga
    54541 gcgccggaac cagcagggac cggaccacga tggtgtcgag cagcacgccg aacgcgacga
    54601 tgaacgcctg ctcggccatc gacaccatcg gcaggaccgc cagcgccgcg aaggtcgcgg
    54661 ccagcaccac gccggccgag gtgatgaccc cgccggtgcg ctgcagcgcg gtgagcgtgc
    54721 cggccctggt gccgtgcgcc agcgactcct ccctcacccg gtgcatgagg aagatgttgt
    54781 agtccacgcc gaatgccacc aggaacacga agcccatcaa cgggaccgac gggtcggcgt
    54841 tggcgaagtg gaagacgtga ttgaacacca gtgcggagat tcccatggtg gccgcgtacg
    54901 acagcaccac ggtgccgatg agcagcagcg gcgccaccag cgcccgcagt agcagcgcca
    54961 gcacgatcag aatcgccacc agcaccagcg gaaccacgac cttgaggtcc cggattccac
    55021 cggcccgggt gtcgatggag atggcggtga agccgccgac cttggcatcc gcgtccggaa
    55081 ccgcgtgcac cgcgacccgg atctgcttga cggtgtccac ggccgccggt ccgtcgggtg
    55141 tggcggcgag caccgcgtcg acctcggcca gcccgttgac caccttgttc agccgggtga
    55201 cggaggtgac accgctcacc ttgctcgtgg ccgcgacgac ctggtccgcc gtggcggcct
    55261 tggtgatgat ggacaccggc gtgcccgagc cgcccgcgaa gtgggcgccg aggatcttct
    55321 ggccggtcga ggagtcggtc gtcttggtga agctgtcggt gatggcgatc ccggacgcct
    55381 tgaactgcgg gacgaagcag gcagcgagca gcagcacgac gcccgcggtg agccagaccc
    55441 tcctgggctt gcggccgacc aggcccgcga cccggcccca cagaccacta ccggtgcgct
    55501 cggcggtacc gaaggcgggc cggaacggcc agaagacgcc acggccggcg agggccagga
    55561 cggcggggat gaaggtcagt gcggccagca tggaggccgc gacgccgatc gcggcgaccg
    55621 gtcccatgct gcggttgctg ttgaggttgc tgaagagcag gcacagggtg cccaggatga
    55681 cggtaccgcc cgaggcgagc accggcttga ggatcgctcg ccaggcggtg cccagggcct
    55741 cgtacttgtt ctgggtgcgg cgcagttcct cctggtagcg ggcgatgagc agcagcgagt
    55801 agtcggtggt cgcgccgacc accagcactg acagcacgcc ctggctctgg ccggtgaagg
    55861 tgatcgagcc gtgcttggcg agcccgtaga ccacggcccc ggccacgccg ctggcgcaca
    55921 tgactccgag caggaccagg aacggcagcg tgggactgcg gtagaccagc agcaggacca
    55981 ggatcaccag tccgacggcg accagcagca gctgcccgtc gatattgctg aacgccccgg
    56041 cgaagtcggc gaacatcccg ccgagtccgg tgacatgccc ggccagcccc gggtgctgcg
    56101 acgcgttcgc ccgcagcacc ttgaccgcgt cgctgaccgg cttggcctgg ttgacgagcg
    56161 gaacggtgaa ctgcagggcg cggccgtcct tcgacacgct caccgggctc acggggccgc
    56221 gcaggccggc cagctttccc gcggcggcgg cgtcggaccg tacggcggcc tggtcggcgg
    56281 aggtgacacc ggacgcccgt tcgtagacca ctacggcggg gtaggtcttg ttgtcggaga
    56341 acgtggactg caactggtcg gcgtgtactg actcggcctt ggcgggcagg tacgccgcgc
    56401 cgtcgttcgt ggccacatcg cccagtttct gactgaacga gccggtcgca ccgctcacca
    56461 ggagccatcc gaggatgagc aacagcggca ccagccaccg cagccggcga cctgacgcct
    56521 ccgtgcgcct aggggtcatg gtggggttcc tccgtacatt cggtgacaca tcgcgtgatg
    56581 cgggggtgct catggtcccg ctcggggctt gagcgcaggt cgagcgaccg gcgcgtacaa
    56641 tttcggcccc tgttggcctg aagcgggcct gtatcggggg agtcccgccc gctggcccgg
    56701 ccggtgaccg gccctttcga gcacccgtcc agcggacctc cacccggtgg ggacacggtg
    56761 tgccgatcgc gtgccctcac tacctgaagt tgcattcgtc ggaggatgga gatgtccatg
    56821 cgtgagtcga cccagatcct cgtagtggga ggcggacccg cgggagccac cgcggccggc
    56881 ctgttggcga aggagggatt cgaagtcacg ctgctggagc gggagcgctt cccgcgctat
    56941 cacatcggcg agtcgatcct gccgtcctgc cggccgatcc tggagctgct cggcgtatgg
    57001 gacaaggtgg aacgccacgg cttccagccc aagggaggcg cctacttctt ctggggggac
    57061 gaggagtggg aggtccgctt cagcgccatg ggcgatgaca accccagtgc ctggcaggtc
    57121 gtcaggtccg agttcgacga gatcctcctg gaccatgccc gcgagctggg cgtcgaggtc
    57181 gtcgagggca tctccgtcaa ggagctggaa ttcgacgggg accgtccggt ggccgcgctg
    57241 tgggccgaga ccaaggacgc cgccagtaag ggccgcatcg ccttcgacta catcgtcgac
    57301 gcctccggcc gcaacggtgt catcgccacc aagcacctga agaaccgcaa gctccacgag
    57361 gtcttccgca acgtcgcggc ctggacgtac tggaagggcg ccaagccgct gcccaagggc
    57421 cccgcgggcg ccatcggggt ggcctcgacg gccgagggct ggttctgggt gatcccgctg
    57481 cacgacggca ccaccagcat cgggctggtc accggcaggg acaggttcaa cgcgcagcgc
    57541 gccgaactgg gcagcatcca ggccgtctac gaccagtcgg tcgagcagtc ggccatcatt
    57601 caggagctga tcgccggcgc ggagcgggtc gccgacttca aggtcgagca ggactactcc
    57661 tacgccgcgg agtccttcgg cggccccggc ttcctgctca gcggcgacgc cgcctgcttc
    57721 ctggacccgc tgctgtccac cggcgtccac ctcgccacct acagcgccat gctggccgcc
    57781 gcctccatct ccagcgtgct gcgcggagag gtgacggagg agcaggcctg ggagttctac
    57841 gggacggtct accgccacgc ctacgagcga ctgctggtcc tggtgtccgt cttctacgag
    57901 agctaccgcg gcaaggacta ccacttctac aacgcgcagc ggctcaccga gcagcagcgc
    57961 gacgggctca acatccagga tgccttcgac cggatcatca ccggcatcgc cgaccttgag
    58021 gacgcccagg acgtctacgc caaggtgcag cagcacctca ccggcgcgga gagcggcgac
    58081 cccatcccgt tgaacaacct caaccgggtg cacgagcaga aggcggcgcc gatgaccgag
    58141 gagagcgcag tgagggggct gtatctctcc ttcttcccca agctcggtct gcggcgggcc
    58201 ggcgagtgag cgcggtgtgg gcggcgtcct gacactggtt gtccgtgaag gacccgggaa
    58261 cggcccagcg gccgggggcg ggagccgagg ctcccgccca cagccgttcg ccgtgcacac
    58321 tcggcagcac ggcacggcac ggcacggcac ggcacggcac agcacggcag cgggcggaag
    58381 gggagttccc cctccgcccg ctgccgtgtg gcccgacttc taggccgagt gcgcgacgcg
    58441 ctcggcttcc cgctcggatt ccaggttcgg ttccaccacc accagtgatg ccggcagggt
    58501 gtcgcgttcg atctgctcgg tcgggtagat cagccgcagg atcggtcctg ccatgaaggt
    58561 agtgaccatg gccatcacga ccatcagcga gtacagcccc ttgtcgagga cgccgagctg
    58621 cacgcccacg gtgaggatga ccagctccgt cagcccgcgg gtgttcatca aggtggccag
    58681 tacgccggag tgccgggtgg agacgccctg cagcttcgcc ccggtgaagg ctccgatgaa
    58741 cttgccggag atggccacca gcaggatcag tccgagctcg cccagatcgc gcgtgctcag
    58801 gtgcgacagg tcgaccttca gcccggcggt gacgaagaag accgggagca ggaagaccat
    58861 gccgacgttc tcgaagctgt tcaacagtcc ttcgcggacg acctgcgggc cgccgcgcgg
    58921 catgacgagt ccgaagagga aggcgccgaa gatgaagtgc acgcccatcc actcggtggc
    58981 ccagcaggac agcatcagcc cgatcagcac cggggtcagc acctgcggcg agagccggcc
    59041 ggacgtcgag tgcgtggcga acagccgccg gaacagtggt cggaccacgc cgatcatcag
    59101 ggccagatag accggtgcga gcagggtgtg ccactgcccg gtaccgctgg cgatggtggt
    59161 caccaccgcc agcagcgacc aggccagcag gtcgtcgacg gccgcgcagg ccagcgccag
    59221 gctgccgacg ggtgtgcgct gcattccgcg gtccgtcagg atccgtgcga gcaccggaaa
    59281 ggcggtcacc gacatcgccg ctccgaagaa gaggacgaaa ccggcggtgc tgtgggccgg
    59341 gtgacggtgg ctcaggtgca gtgccagtac caccccgagg ccgaacggca gcaggatcga
    59401 gctgagtgac accgcggcgg cgatccggcc gcggccgcgc accagggagt gttcgagctc
    59461 gaagccgatg acgaacatga agaggatcag cccgaggttg gccagtgccg agaggaacgg
    59521 accgaccgag gcagggaaga ggtgccgggc gacagcgccg ttgaagagcg tggggccgag
    59581 cagtatcccg cccaggatct cacccagcac gggaggttgg ccgatggcct tcgcgccggc
    59641 gcccaacagt cgggctaata gcaggattac ggcgattccc aagaacagtg tggcagcctg
    59701 acttcctgtc atggcgtcta ctcctcgtat gtggcggaca gtgtcatgtc atgccccgcg
    59761 gggagcgggt gaccgggacc cgtcggggcc ccgcccgtcg gtcggtaccg ggctcccaca
    59821 ccactggatg tcgcgtcacc tgactgacat gcctccgatg agtaccgggc ctgcctcaag
    59881 gacgcctggc agacgagtca ggacccgccg ccacggggcc gccgcgcccg cccgggcggc
    59941 accggtcgac cgcagcccca tcggagttcg agcgggagcc gggaacctgt gcgcggaagc
    60001 ctggaggaat ggaaccgtcc caccgccgat ggccggcccc gagccggccg acgaaccggt
    60061 ccggggcgac atcgccctgc tggagtaccg accggtgcca gggtctgtcc ggctggacag
    60121 gccctacccg gccccggtac ggacccgacg acacagcaag aaggtgtgtg gatgcccatc
    60181 ccgctgcccg acccgatgaa cctgccggcc gagcgacgct gcccgctcga tccgccggaa
    60241 gaatacgcgc agttgcgtgc cgaacggccg ctgagccgtc tgcggcttcc gggcgggcgg
    60301 atcggctggc tcgtcacccg ctacgaggac gtgcgcgcga cgctggcgga ccagcgcttc
    60361 agcccgcccc tcatccaggt gacccccgcg acggacctgc cgctgcccga ggaggagctc
    60421 caggtaccgc ccggggtgtt ctccgcgatg gaccctcccg agcagagccg gtaccgccgg
    60481 caggtcagcc ggtacttcac ccgcaagcgc acccgtgaga tcactccccg actcacacag
    60541 atcatcaacg accagctgac cgccatgatc gaccacggcc cgcccgtcga tctggtcagc
    60601 tggttctccc agcccatccc gacccgcgtc atcaccgaga tgctcggcat ccccgagccg
    60661 caccgggccg agtaccagcg ctggatcctg gcgatgctct ccctgaagac cgacgccgac
    60721 caactgcgcg aggccagcga cggcctctac ggaagcctgg gcgaactcgt ccgtgccaag
    60781 cgcacggcgc ccggggacga catcgtcagc gacctgctgc accacggcac cagtccgctc
    60841 aacgacgacg aagtcgtcgg catcagcgcg ctgctgctga tcgccgggct ggagaccacc
    60901 gccaacatgc tcggcctcgg cacgttcgcc ctgctgcaga accctgacca ggccgcgaaa
    60961 ctgcgggcca acgaggatct gctcgacacg gctgtcgagg agctgctgcg atacctgacc
    61021 atcgtgcagt tcggcctcac ccgcacggcg cgtgaggaca ccgagatcgc cgggcagctg
    61081 atcagggccg gcgagaccgt cgtcacctca ctggccgcgg gcaaccgtga ccccggtgtg
    61141 taccccgatc cggaccagct ggacgtgagc cgccaggggg cgccgcacat ggcgttcggc
    61201 ttcggtgtgc accagtgcct cggcgcccat ctcgcgcggg tggagatgaa gattgccttc
    61261 gaggccctgc tgcgcagact gcccgggctg cggctcgcgg tgccggccga ggaagtgccc
    61321 accggtgtgg acaaggtctt ctacggagtc cactcgctcc cggtgacctg ggacacctga
    61381 tccaccgcgg gaagtgacag cgcgaaacga agccggtccc ggtcgaaagc cggggccggc
    61441 ttctcgctgc gccactgggc cgctccgtcg catcggcttc gccagggcag cgccgagcgg
    61501 gcccggagct gcttgctccg ggcccgcccg accgactgcc ctgctgcgga ttcaggaggc
    61561 ggtggcctcc agcgcgtagt agagccaggg gcagggaagc gcggtcgcgg tcgagagctt
    61621 cagacccgcg tcggtgaaca gctgggcata ctcgctctgg ctgcgctcca gaccggtggt
    61681 catcaccagc atctcgatgt cggagatggc accgcccagc gcgtcgcccg ggtcctcgtc
    61741 ctcgccctcg gagagcactg aggacagcac gaccacccgc ccgcccggtg ccatcgcctt
    61801 gcggatgttg gagaggatct ggacgctctc ctcgtcgttc cagtcgtgga ggatgttctt
    61861 cagcacgtac aggtcggcgc cctcgggaac cgagtcgaag aacgagccca cgacgacctc
    61921 gcagcggtca ccgaccccgg cgtcctcgat cacggcagcg gcctcgacca caccgttggc
    61981 ggtgtcgaag atggtgccct gaaggtgtgg attggcggcc agaatggcgg tcaggtgggt
    62041 gcccttgccg ccaccgcagt ccacgatggt cttgaaccgg ctgaagtcga agtgctcgac
    62101 gatcgccggc acctgggcgt cgctgcctgc ggacatcgcg gcgtggaagg tggccgcgag
    62161 cttgggattg gtcttgatgt agtcgaacag cggtgcgccg ttggcgatct ggaacgcgtc
    62221 cacaccggta cggatcgact cctcgaaagc tccccaggcc gcccagatct cgggcgcggc
    62281 gtggtagtcg gacagcgggc cgaagaaggc cgacagcgga gcgaggtggt agccctcgct
    62341 gtcgacggtg agcagcttgg ccttcgtggc ggcgtacagc aggcgacgca ggctgccggc
    62401 atgtgcgtcg gtgacctcga ccaactgtgc ggcggtacgc ggcccgtcgg ccagggcgtc
    62461 gaggacgccg agcgatgaca cggcggcgcc tatctggtgc agggcgaagc cgaaggaaag
    62521 cggaaggtat tccgccgcgg tcgccggctg tccagagatc tgactgctca ttgcactccc
    62581 catggttcct tagttcggcc cgccgcgcgg cgcggcggcg gtcagtcctt ccggcacgac
    62641 accagcgtgt cgtggtcggc cagtggccgg tgggtgatgg agctgaagcc ggtggctcgg
    62701 gcctgtgctc ccagctcggc gacggtgtac tccctgccgc cttcggtgac cagcagcatg
    62761 ttcaggctgg ccaccaggtt ctcggtgtcg tcccggcgtt cgccgagcat ccggtcgtag
    62821 accagcactg tgccgccggg gctcagggcc gtgtatgcct tggtcagcag cagccggcgt
    62881 tggtccgggt cccagtcact caggttgtgg ccgaagatga tcacgtctgc cggcggcagc
    62941 ggatctctga agaagtctcc cgcgtgaaag tgcgcccgtt ccgtgaggcc gagttcggcc
    63001 atgtgctcgt cgaagaccgg ctccatctgg ggcaggtcga agacatgccc gaccaggtcg
    63061 tcacgggcgg cgagcagctg cccggtcaga tggccccggc agccgccgac gtcgaggacg
    63121 gtgcggaacc tggtgccgtc cagggcgtcc agaagcttgg cgccgaaccc ctcggtgagg
    63181 ccgtccatca tccgcgcgaa gcggtcgacc gccaccgggt cctgcagcat tccggcgaag
    63241 tcgccgtcgg cctgcggctt gccggtgcgc agtgcctctc ccagccgccc gtagacgtcg
    63301 tacagattga tgtccgcgcc gatcaggaag ccggtgacgg cgcccggacg gccggcgacc
    63361 agatggcgat cggcgccctc ggcgttgtgg tagcggccgt ccacgtcccg gcgcagcagg
    63421 ccgcgggcgg ccagcagggc aaggaactcc ggcagcccgc ggccgtgcag gcgtaggagc
    63481 gtgcgcagtt caccggcggt cgccgggttc tgggcgagga ccgtgaacag atccagacgg
    63541 acggcggtga gcagggcctt ggcgtcgcag aacgcggtgc cgagccggat gatccccgct
    63601 gcggtcccag ggtccgctcc ggtcgatgtc atgggcggtt ctcctttcac cggcggcaat
    63661 ctcgcagcgg cggaccgagg attgctcgac tggcgctagg gcctgtccgg ccggacatgg
    63721 ggcggacatg aagggcacct catagctacc gctgggaggt ggtccccgcc tcgggcgggt
    63781 gcggtggggc gggtatcgac cgggcttcga gccggtcacc agaccgagcg cccaagctgt
    63841 gcgcgataca agcggtgagt gtattgagag ggcggttccc gtatgagtga gtcgtgcccc
    63901 gtcggctacc ccatcccctg ggccccgacc ccggacatcc ctgaggagtg gaaggcactg
    63961 cgcgagcggt cgctcgtgga gatcactctg cccagcggcg aacccgccgt gctggtcacc
    64021 aggtacaagg acgtacggcg gttgttcgca gacgagcggc tgagccgcaa cacgttcggc
    64081 cgggcgtcga gggtgtccgc cagcaacgac ctgttcggcg acccgaatgt cgacaacgat
    64141 ccaccgcgct atctggagga gcgctccgtg gtgatgcggg cgttcagcgc ccgccgcatc
    64201 gaggcgctgc gcgtgttcgt caagaaggtc gtcatcgacc tgctggacga gatggaggcg
    64261 ggaccgcagc ccgccgagct gatggaggcg ttcgcatatc cgctccccat cctggtgatc
    64321 tgccagatgc tgggagtgcc cgcggaggac cgcacgaagt tccgccgact gatcgacggc
    64381 tatctgtcgg tgacccggct gccggaggac gaggtcgagg agtgccgcaa gcagtactgg
    64441 gactacctca ccgaactgat cgactccaag cgggcccagc ccggtgacga cctgatcagc
    64501 gagctgatcg agatcagccg ggaggacccg ggcaagctga ccgactacca gctgcagaac
    64561 tgggtcaaga ccctgctgat cgcgggctat gtgaccacgg cctcgcagct cggtaccagc
    64621 atggccgtcc tgttgcaccg cccggaggtc gccgacgatc tgaaggccga cctgtcgctg
    64681 gtgccgtcgg cggtggagga gctgctgcgc taccaaatca tgggcacctc gctgggcacg
    64741 ctgcggtacg cggtcgagga catcgaactg tccgacggcg ccgtcgtccc gaagggctcc
    64801 tcggtcctgc tctcccagga gtccaaccac gacgaggagg tcttcgagga cccgctgacg
    64861 ctggacatcc ggcgcgagga caaccaccac ctgaccttcg gtgccggcat ccacttctgc
    64921 gccggcgcgg cactggcccg catggagctg caggaggcga ccgagggcct gctgcagcgc
    64981 ttccccggac tgaaactggc catcccgggt gacgagttgg tgcgtcccga gggcggcttc
    65041 ctcgccgggt acaccaacgt ccctgtgacc tggtgacggc ggtgggcagc ctgagagtct
    65101 ccgccaacca ggacacgtgt gtgacgagca gcctgtgcgt ctaccgggtg ccccaggtgt
    65161 tcgaccagga cgaggacggc ctggtactcg tcgtgaacgc ggagccgccg caggagctgc
    65221 gtgaggattt gctgcacgcc cagcggagct gtccgacccg gtcgatccgg atcgaggaac
    65281 cggcggtcgg cgccggcgcc gacggcgccg acagcggttc agggcaggcc gcgaccggtt
    65341 gagcaccggg cagagttccg gccgggcccc gccgttcccc tcctgggagc ggcggggccc
    65401 ggccgtgtcc gccgggccgc cgcactccgt acccggggcc ggggtgcggc gagccctcaa
    65461 gcggcaatgg aggcagcggc aagcgccgcg tgctgccatg gcggtatgcg tatcgtcttc
    65521 acttcctggg cgtggccgtc acacctctac gcgatggtgc ctctcgcgtg ggcctgccgg
    65581 gtcgccggtc atgatgtgct gatggccagt cagccggccc tcacatacgc cgttctgcgt
    65641 accggcctgc ccgccgcacc ggtcgggcag aatgtggacg cggaggcggt cttccggaac
    65701 atcgtgctga cgccgccttc cgcgcagccg ggatccggcg gcggtccgcg cgtcctcgac
    65761 ctgctgagca acctggccca ggccatggtc gacgacctcg tcgagctcgg aagggaatgg
    65821 cgcgccgacc tggtcgtctt cgatcccacg gccttcgcgg ggccgctggc cgccgccaag
    65881 ctgggcatcc cggccgtgcg ccatctctac ggcaccgatc tgatgagcgt cgtcgggcgg
    65941 ttcgtgaccg gtgcgctcgg tccgctgagc gagaagctcg gcctggacgg cgtggacccg
    66001 ttcggggtgg ggaccgtgga cccgtgcccc gggggactgc aggtccccac cgcctcgcgg
    66061 cgcctgccga tgcggtacat cccgtacaac ggcccggggc tggcgccgcc tcggttgccc
    66121 gaacggtcgg gccggccccg tgtctgcatc agctggggta ccaccatggg ccggctggat
    66181 cccgggctct tcctcgccgg cgacgtggcc cgggcgatcg acggcctcga cgtggatgtg
    66241 gtggtcgcga gcacgcgcgg ccagcgggag ctgctcggca cgctgccgga cggcgtcgac
    66301 gtggtggagt ccgcaccatt gcacctgctg ctgccccagt gcgacctgat ggtcgcccac
    66361 ggcggcgcgg ggacgctgct gaccgccctg tcccagggtc tgcctcaact cctcgttccc
    66421 cggctgcccg accatgtgcg gcactcgggc cggctcgccg aggcgggcgc cggagtcgtc
    66481 ctcccggcgc cggtggacgg accggagccg atccgcgagc ggctcgccga gttgctggcc
    66541 gggcccggat accgggagag cgcccaacgg ctgcaggagg agatgcgccg gcagcccgca
    66601 ccggcgcagg tcgtcggaga gctggagagc atcgctgcgg gcgcacccgc gacgtgacgg
    66661 tcgcggccgg ccgccccccg actccgtgtc caggattctt cgaccggctc tcagtgcccc
    66721 ggtgcgagcc tcgcaggact tccggccggc cagggcccag gccctgtccg gtcgatcacc
    66781 cctggatgag gagttcctca tgtcggcgcc cacctccact ctgcatgtcg tcatcatcgg
    66841 cgcgggaacg ggcgggctgt gcctggcgca cggcctcaag cgcgccggag tcagtgtcgc
    66901 ggtctacgaa agggacgcca cacgggccga cgggctgcag ggataccggg tcgggatcaa
    66961 cccggacggc acccgcgccc tgcgcgactg cctgcccccc gatctgtacg ccacgttcct
    67021 ggccacctgc gcgcggccgc cggagtacgt gaacttcctg accgaggggc gcaaggaggt
    67081 cctgtcgctg gacggcttca agtccgacga cgcggtcgac agcgagaagt ccgtgtcccg
    67141 gatgacgcta cgtcaggtac tgctgaccgg cctgcaggac atcgtccact tcgggaagac
    67201 cttcaagcgc taccggacca atgacgacgg ttccgtcacg gcgttcttcg aggacggcag
    67261 ctcggtggac ggcaccgtgc tggtggcggc ggacggcagc aactcgcggg tccggcggca
    67321 gtacctgccg cacgcccggc tggaggactg cgggccgatc ggcatcaccg gcaaggtacc
    67381 ggtcaccgat gagaccgtgg cgctgctcac cccgaagatg cggcgcggca tctcgatgat
    67441 ctacgcaccc aagggcgtct tctgcatcta ccacgcgatg gagttcccct gggacgccga
    67501 tggcgccccc aaggacggca tcggttccag cgacgccgag ctcctcgggc agtggcccgg
    67561 gctgaccttc gacaataccc gtgactacat caactggggc tatgtcaccc gtgccaagcg
    67621 gctgccggac gacaccttga agatgaaggg ccccgacctg taccggctgg tcaatgagcg
    67681 caccacggac tggcacccag acctgcgcaa gctcttcgag ctcgccgacc ccaacagctg
    67741 cttcccgatc aagatccgta ccgcggtccc cattccgcag tgggagacca cccacgtcac
    67801 gctgatcggc gacgcgatcc acaccatgac ccccggccgg ggggtcggcg ccaacacggc
    67861 actgcgcgac gcccggctgc tgtgccggat gctcgtcgcc gcccacgaag ggcgggaacc
    67921 gctgctggcg gccatccgcg actacgagac gaagatgatc gagtacgggt tcgacgccgt
    67981 caaggagtcc cgtaaatcgg gcggcggcac cgggcccgac cagccgttcg tcggccggat
    68041 cctgctggcc gcgctgcgta ccacgatgcg cgtcgtcaat cacctgcctg ccctcaagcg
    68101 ccgactggcc gactccgacc ggtcctaccg cgggcacggc cgggaggact aggacggttc
    68161 ggccggtcaa ccgtccagga cgccaccagg ctcattcgag cagtggtcga tacggtccct
    68221 catcgggaga acacggcgcg cgggagggaa cagatgctgt acgaggaact cgccgagatc
    68281 tgcggcccgg tgctgcggaa agtgctggac catcccttct gggccggcct gcgggacggc
    68341 tcgctgccgg tcgggtcact ggcacgcttc gtcgagcagg acgccggatt cctgctgccg
    68401 gcctacgccc gcgcgctggc ccgctgcgcg gccgtcgcgc ccgacgaggc ggacaccttt
    68461 ctgttcgggc agtcggtcac cggcacgctg gacgccaggg acgagttgcg ctcgtcgtac
    68521 ctgtcgctgg ctggcgaact cggcctgccg gaactcgacg cccggccggc gatccacgcg
    68581 gccacccacg cgcacacctc gttcttcacg gctgccagcg cctcttcctt ccatgcgggc
    68641 gtcggcgcgc tgctgcccat ggtgtggttc aacgccgagg tgtccgacaa cctcctgcgg
    68701 aacgccgtac ccggcacgcg ctacgtgccc tggattcgca gttaccaccc cggtgagtcg
    68761 taccagtacg cggtgcaggc cttccgcgac atggccgacc gggtcggcga gagctcctcg
    68821 gccgcccagc gccgggtgat catcgaccag ttctccctca gcatccggta cgagtgggca
    68881 ttcgccgaat gctgcgcggg acagccctcg tggccggtct gagacgagcg gccaccgcac
    68941 cggcgggccg acgagaaagg cgagcaatgg ccaccaacga tctcgacctg atggatccca
    69001 aggtgttcaa caacgggatc ccctacgact acttccgcca actgcgccat tccgaagggc
    69061 tgccgctggg caaggacacc gacggcgagc ggttctggta cctgacgcgc catcgggacg
    69121 tgtccgaggt ctcccgggac accaagcggt tctcgtccag cccgaccacc atgacctcca
    69181 tccgcaaggt ggaccccagc ccgccgatca tcaccttcct ggacagcccc gaccacacca
    69241 gactgcgcaa actgaccttc aaggcgttcg ccccggcacg actcgccgct ctggaggggc
    69301 cgatccgccg catcgtcgac tcgctgctcg ccgaggtggc cgagaagggc gagttcgacc
    69361 tggcggagga catcgcgctg cgtctcccct tcgaggtcct gctcgagctg ctcgacatcc
    69421 cggccggcga ccgggccatg atgctcggct gggccggcca gacggtgaac ctgggtgacg
    69481 cggagtacga ggcggccgcc gccgagggcg gcctggactc cttccagaag atctacgagt
    69541 acctgctgga cttcgcccgt taccgcgcca agaacctcac cgacgactgc ttctccgtcc
    69601 tgctgtccgc ccgcttcaac ggtgagcggc tggggctccc tgaccggctc accccggacg
    69661 aggtcgggct gttcgcctcc acgctgatca cggccggcag cgagaccaca tactgctccg
    69721 tcacgggcgg cgtcctcgcc ctgatggaga accccgacca gctgaccgcg ttacggggcg
    69781 accgcaccct gatgcccggc gccgcgaacg aggtgctgcg ctgggtaact ccggtgaccc
    69841 acttcgcccg cagggccctc gtcgacaccg agatcgccgg ccagccgatc ggcgcgggcg
    69901 agcgggtggt gatgtggtac acgtcggcca accgggacga agaggtgttc acggacccgg
    69961 accggttcga catcgcccgc actcccaacc cgcacctcgc cttcggcggc ggcggtccgc
    70021 atgtgtgcat cggcaacgcg ctggccacca tggagctgcg ccagttcctc gaaggcatcg
    70081 tcgacctgct gtcgcggctg gagatcgccg gtacgccggt gcgccccgag accaacttca
    70141 tgaacagcat caagtacctg cccatgcgat ttcgctgacc cgggtggatg tgacgaatga
    70201 ccagtgagaa cgcggcgacc ccgccgcgta ccgccctgat caccggagcc aaccgcggca
    70261 tcggccgcgc ggtcgccgcc gagctccacc accgggagct ccaggttgtg gtggccgcgc
    70321 ggctggccgg cgagggccgc ggcgcggctg ccgggatcgg tcccggagtg cggtcgtgcg
    70381 tactggatgt caccgatccg gacagcgtga agctggccgg atcggaggcc gggcccgtcg
    70441 atgtgctggt gtgcaacgcc ggcgtactgc tggacgcccg caccgatccg ctctccgtgc
    70501 cgttggaact cgtcgaacgg accttgcggg tgaacctgct cggcacctgg cgcgttctgc
    70561 aggagttcgt tccgcccatg gtccagcggg gatggggccg ggtggtgatc atctccagcg
    70621 gcaccaccgc agacttcggg ggccggctct tcgccggtac tcccggctac tccctttcga
    70681 agagcgcgct caacgggttg acgaccatgc tggcggccca gaccgccggg accggtgtcc
    70741 tggtgaacgc cgtgaacccg ggccgggtgc gcacccggat gatgccgacc caggagcaac
    70801 tccctgaagc tgccgcccgg ttcatcgccg aggtggcgac ccttccggac gacggaccga
    70861 ccgggcactt cctcaccgag aaacgcggat cgggctgagc ccgcggcgtc ccaggaacag
    70921 gagatccgat gcaattcgac ttgaccggca aaacggccgt ggtcaccggg gccggcagcg
    70981 ggatcgggct ggcgtccgtc caggcactcg cctcggcggg cgcccaggtg ctcggcggtt
    71041 cccggaccat cagcccggag ctgctggacg ccacgccgca cgtgttcgag gtcgatctgc
    71101 tcaccgaggc gggaccgacg gcgctgctgg aacacgcgct cggcacattc gggggcgtcg
    71161 acattctcgt caacaacgtc ggtggcgggg tgaagctggc gaccgggttc ctcgacatcg
    71221 aggacgagac ctggcgccac accttcgagc tgaatgtctt cagcatgatc aggacgacca
    71281 gagcggcgct gcccagtctg gtcgagcgaa ggggcgcgat catcaatatc ggctcgatga
    71341 acgcgagcat ggcggacccg gcactcggcc actattcggc tgccaaggcc gcactggcca
    71401 acatcagcaa atcgctctcc ctggaattca gttcgcaggg cgtcaccgtc aacaccatct
    71461 ccccgggacc ggtgcggacg cggctgtgga ccaatccgga gatcgcgcgc cggctcggga
    71521 tcacgaccga ggagttcctg gagaccgtcc ccaagatggc cggtctctcc accggcaaga
    71581 tgatcgagcc cgatgagatc ggggcgctgg tgctgttgct ggcctccggc aaggtgccga
    71641 gcatcaccgg ctccgactac ttcatcgacg gcggcatgag tcgggccgcc gtgcgctgac
    71701 cgggtcaccc gcgagcggga acaacaagga gtcggcccca gccatcaggc tggggccgac
    71761 tccttgttgt ttacgtcagc cggcggtcgc ggtgaagatg gcgaccgcac cgcgaatcgt
    71821 cacacggtac tcggggaagt acttcgccag ctgccgttcg aggcccgccg ggtcgtcccc
    71881 ctggttctgg aagttgccgc gccggtgctg ctccagcacc attttgctgg tcagcctgtt
    71941 catcggaacg ccctcggcga gcacggtggt gccgaacagc acaccaccgg gccggagggt
    72001 ctccgcgaca tgcttgagga tgatgccctt ggtgtcccag ccgccgggga tggtgtggaa
    72061 cacgaggttc atggcggccg agtcgaagtg ccggctcggc agtggcagcg gttccatcag
    72121 attggcctgg cagatcgccg gccggtagcg ggccagtcgg cccgcggaca tgtcaaggca
    72181 ttcggagttg aggtcgagca gggtgagttc cggcgtcttg gtcgggaacc ggcacttgtc
    72241 cacgaagtaa ccggtgccgg ggccgatgtc caggtgacgg ttgccggcgg aggagttgta
    72301 gagccgccgc atgactccgg ccgggcagcg ccacaccaca cggcagaaca cccccagcac
    72361 ccatttgtcg tagatcccca gcctgctgcg gctgtacacc tgttgcgcat gaacgatccg
    72421 tgggtccagc tccgcggact cgggagcgga ggcgggagtg tcgctcgtca tatggctctc
    72481 cagtgttctc agcggcgccg gaaacgggcg ctgcccaggg cagcgaagac aaccgtgatc
    72541 ccggcggtcc agatcagcga acgtgagacg aagtacccgg cgtcatgacc gagcagagca
    72601 tgggcgtggc tgcccaaggt gagcgcccgc accgcgtcgg ccatcacggt gaccggctgg
    72661 ttctcggcga atgcctggag ccatcccggc atggtcccga ccggcacgta ggcgctcgat
    72721 gcgaaggtca cgatgaagac gaccatcgac acgccctgtg cggacttgac gttgccggtg
    72781 aacagcccga cggcgatgaa gacccagctg aaggcgaccc cgaacagcag gcacagcgcg
    72841 aacgccgcca acccgctcag gacggatgcg tgcagccgga agcccacggc gaaaccgacc
    72901 cctgtggtga tcgccaggac gaacgccagg atcccggtgt ccgccagtac ccggccggtc
    72961 agcacggccg aggacggaaa gggcatcgac cgcagccggt cgatgaagcc gccctcgacg
    73021 tcctcggcca tcccgatggc ggtgcccagc gtctggaaga gcacaccggc ggtgatgaag
    73081 cccgggacgg agaagtcgac gtagtccagg ccctgactcg tgccgatggc gccgccgaag
    73141 atgtagcgga aggtcagcat gatcgacgtc atctgcagga cgctcagcac gatgagttcg
    73201 gtccttcgcc agaacgtcag cgtggtccgt ttcgccagga gccccgtact cgtcagcagg
    73261 ccggccctgc tctgtgatgt ggcgaccgcg gtcgtcatgg gcattccatc cttccggatc
    73321 cggtcacacc gattcggcgg cggacagggc gtgctgcttg ttggctccga cctcttcctc
    73381 cggccgctga tcggtcagcg cgaggaacac ctcgtcgagg ctgggctcgc gcacgctgat
    73441 gtcggcgaga tccacggccg ttccctcgat cgaccgcagt cccgcgatca gccactgggc
    73501 cgtgtcgtcg ttgccgggtc ccgcggccac gctgacgcac cgcgtcgcct cgtccacctg
    73561 cggctcggcg ccgttctcgc gggccagcgc ggcggcgacc ttgggcaggt ccgcgcggtc
    73621 gtgcacatgg acctcgaaga ccttgccacc gatcctgctc ttgagctcgg caggggtccc
    73681 ggaggcgacc gtgcgcccct catcgatgat cacgatgtgg ctggcaaggc gatcggcctc
    73741 gtccaggtac tgcgtggtca gcaggacatc ggtgccctgt tcgaggaggg cgtcgatcgc
    73801 gtcccacaga tcgagccggc tgcgcgggtc cagcccggtc gtcggctcgt ccaagagcag
    73861 caggcgcggg gcgctcacca ggctggcgcc caggtccagt ttgcgccgca taccgccgga
    73921 gtaggtgcgc accagccggt cggcgtcgtc ggtcaggtcg aacagctcca ggatggcggt
    73981 ggcattggcg cgggcctgct tggcccgctg gccgaacagc cgggccacca actccaggtt
    74041 ctcccggccg gtcatggcct ggtccacggc ggcgaactgg ccggcgaggc cgatcgcccg
    74101 gcggaccgct tccggctctc gccgggtgtc gtggccgacg acgcgcagct caccctcgtc
    74161 cgggtagagg agggtcgcca ccgcccgcac gaaggtcgtc ttcccggccc cgttggggcc
    74221 cagcaccgcc accaccctcc cggactcgac ctccaggtcg agtccgttga gggcggtctt
    74281 ctttccgaaa cgcttgacca gtccccgagc ttcaatcgtc agcgccacaa gatttcacct
    74341 cgtttgcttc gcatccgtgt gagggcatgg cctccggccc atggtgtaaa acggcaccgg
    74401 agtgccactg gagcgggact tgatcggcgg cacggcggca cgacacgcga tcggctgtcc
    74461 gtcagaccac cagttccacg ttgtagtgcg acagccagga gttgaactgc agcgccgtct
    74521 cgatgtgcat ccggctcggc cagtcattgg cggcgcccgg gttgcgcaac gtgtgttcca
    74581 ccgccttgtt gtccaggtac ggcaggatcg gtgagttcgg atcgctgatc agcgcggtca
    74641 gttcctcgtg cagcatcgcc gtgtaggcgg gatcctgggt gaccggccac gggctcttct
    74701 tgcgctccag cacggacgcc ggcagcagat cgcgcacggc tgcccggagg atggacttct
    74761 cccggccgtc gaaggtcttg aagctccacg gagtgttgta caggtactcg acgagccggt
    74821 ggtcgcagta gggcacccgc agttcgaggc cgtgggccat ggagagccgg tcgctgcggt
    74881 ccagcagcat cggcatccac cgggtgagcg tgagatagcc gatctcccgc atccggtact
    74941 cctcggggct ctcgccctcc tggtgcggcg cctccgcggc ggcctcgtgg aaggagtccg
    75001 tgtagtagcg gcgcatgtcc agcttctgca gcagcccgtc gtcgaagagc ccccggccct
    75061 gtcccttcat ggagctcggc tgcagcgcct catgcgccac ccaggggaag gcgtcggcgc
    75121 ccacggtctc cggattgaac atccagttgt atccgccgaa tatctcgtcc gcgacctcgc
    75181 cgaccagcgc caccgtggag tgcgtcctga tctcgcgtga agtgaggtag ttcgaggtgt
    75241 ccatgtcgcc gagcgtcgag ggcgcgtcct gcgcgagcag cgccatcaga cgggtcttcg
    75301 ggtccatcag gtcgtggctg ctcagccgga tgttgacgtg gtcggaggag aggtgctccg
    75361 cgacctcgat cgcgaagggc tcgtccggcg agaagcggac gtcgtccgcc tggaacttct
    75421 cggcgtagtc gtcgaatgtg gtcacgaagg tgcgcagccg cgcgccgtcc agcttccagc
    75481 gccactgggc ggcgatcgcg gtgagcgagc tggagtccag gccgccggag agcgcggtgc
    75541 acagcggcac gtcggccacc agctcgcgca gcacgatgtc ctccagcagc gagcggacgt
    75601 tggtgatggt ctcctgcagg gtgtcggtgt gcggccgggc ctcgagctcc cagtaggtac
    75661 ggtcgacgac gcccgcgctg ccgatggtca gggtgtggcc gggcagcagc tcgcgcatgt
    75721 cgcggaagac cgcctgcccg ggcttcttgg cgacggcgaa catctcccgc aggccgtcgg
    75781 cgtcgacgac cgggcggatc agcgggttgg ccagcaggga tttcggctcg gagccgaaca
    75841 ggacgccttc gggcagccgg tggtagaaga gcggtttgac gccgaaccgg tcgcggacca
    75901 ggagcagttc ctcgcggcgc aggtcccaga tggcgaaggc gaagatcccc tccagccgct
    75961 tggcgcagtc cgggccccac tccaggtagg agcggagcac cacctcggtg tcgctgcggg
    76021 tgcggaactg gtggccgcgc ccctgcaact cggtacgcag ctgcttgtag ttgtagacct
    76081 caccgttgta gacgatgacg gcgacggggc gcccgtcctc ctccaccgtg agcggctgca
    76141 cgccgtcggc cagatcgatg atcgcggtac gggtgtgccc gagcgcggcg tgcctgctga
    76201 cccacagccc ctggtcgtcc acacctcgct tggcgaccgc gtcggtcatc gcttgcagca
    76261 ccgaccgctt ctgcgacagg tcctgcccga agtccaccca gccggcgatg ccgcacatct
    76321 gtgtctccct cagttgtgtt ctgaaagccg tctgtcttcc aaaagtcgtc ggcagcatgc
    76381 gggtgccggt tcgaagggac cttgacgcct gctagatccc gccgttccac caggcctcca
    76441 ccgtggttca agtgaggttc gaggcggtgc cccgaacctg tgcggacgtt gatccggacg
    76501 agaggtggac gtcgatgacc gcgcaggaca gcgcttccgg ggcccagggc acagccggat
    76561 ggttcgacgc gagcctcccc ccacagcagc aggtgctcgg attcctctac gccaagtggg
    76621 tcatcggggc gctgcgggcg ctggtggagc tgaaagtgcc cgacgcgctg gccgacggac
    76681 cgcggaccgt cgcgcagatc agcgagacga cgggcacgga tgccgacgcc ctctaccggg
    76741 tgctgcgtgc ggtcgccgcg gccggcgtgt tggaggagcg gaccgacggc agcttcgtac
    76801 tgacgcccgt ctcggcgggt ctggtttcgg acgccaccga cggcatccgg gacatgttcc
    76861 tgttcgcctc cgaccccacc ctctggcggc cgtacgagaa tgtggcgcac agcgtccgca
    76921 ccggcgaagc ggccttcaac aacgtcttcg ggatgtcgta ctacgagtac accaaggcca
    76981 atccggccag cggcgcggtg ctggaccggg cgatgaagca gaaccactat cccggtaccg
    77041 accggatctt cgccgaattc gacttcgggc gctttccccg gatcgcggat gtcggcggcg
    77101 gcaggggcca gttcctggcc gaggtgctgc gccgccacgc cggagtcacc ggcgtactgg
    77161 ccgaccaggc ccacacggtc gccgacgcca aggagacctt cgcggacgac gggctggcgg
    77221 accgggtcga gatcgtcccg accgacttct tcgtcgaggt gcccgccggc tgcgacgcat
    77281 acttcatcaa gcacacgctg cacaactggg ccgacgacaa ggccgagctg atcctgcgcc
    77341 ggatcaggga ggccatcggc ggcaacggcg aggcgcggct gctcatcgtg gagaacctgc
    77401 tgcgcggtcc cggcgagtgg gacatcggca agctgatcga cgtcgagtcc ctcgccgtgc
    77461 tgggcggccg tgagcgcagt cgcgaggaat ggaaccacct caccgccgca gccggtttcg
    77521 cgccggccaa cgagccggtc ccgggtgaca tcgccctgct ggagtaccgg ccggtctagg
    77581 agcgcgcgcc gggaatccgt gccaggctcc agtacgggga gcccgtggcg ccggaccggc
    77641 aggggcggcg ggcgggaccg tacggcggag ttgtggtaac ggcctcagga gttcgagatg
    77701 gatctgggtt tgacggacaa gcgggtgctg gtcaccggcg ccacgcgggg catcggccgg
    77761 gccactgccc gggtgttcgc cgcggagggc gcacgggtcg cggtcaccta ccacagcaac
    77821 gaggtggcgg cgaaggagct cgtccaggaa ctcggcggag cggaccgggc ctgcgcggtc
    77881 ccctacgacc tcgcggtacc cgagtcgatc gagcaggctg tgcgctcgat cgaggaccgg
    77941 tggggcggcg tcgacgtggt ggtggccaac gcccagacct gggagtggat caacccccag
    78001 gagatgcccc agtaccagga cttcccgatg gacttctggc tgtccaagta ccgggagaac
    78061 gtcgaaggcc atctgtggac ggtgcgtcag gccctgggcg ggatgcggga acgcggctgg
    78121 ggccgggtcg tcctgctgtc ctcggtcacc gcgacccacg gaaaccccgg ttctgagatc
    78181 tacagcgcgg ccaaggcggc cctgcacgga tttgtccgcg gactcatgtg gaccggcgac
    78241 ggcgtgctgg cgaatgtggt ggcgcccggc ggcaccctga ccgagagcct ggaggcggtg
    78301 gacccggcgc tgctggaggt cgccgtacgg gagacgccca gcggccgtct gagcaccgcg
    78361 gacgatgtgg cccggctcat cgtcttcctg tcgtccgagg cgaacggcaa tgtcaacggg
    78421 caggtcatcc atcccgccgg cgggcgctga gatgctgcgg gacgagctgt cggcgatcgc
    78481 gaaaccggtg ctggccgcag tgttggagca tcccttctgg gacggtctgc gcaagggcac
    78541 gctgcctgcg gactcgctgt ggtacttcgc ggagcaggac gcgcgctatg ccgtgccggc
    78601 ctatgcgcgg gcgctggccc gcacggccgc gatcgccgac caggacgcgc acagcgccct
    78661 gatgagcgga gcggcgagcg tcaccctgga cgcggtcggc aggatggacg gcgaactggc
    78721 cgccctggcg gcggagctcg gcaggacggt gcggaccgtg gcggtgagtc ccgcgaccca
    78781 tgcacacacc tgcttcatgc tggcggcccc ggcggtctcg ttcggcgccg cgttcggcgg
    78841 gctgctgccc atgacctggt tccaccaggc cgtctcgcgc gatctgcggg aacggtgcgt
    78901 gcccgggtcg cggtacgagg cgtggatcga tcagtactgc ccggaaagcg gtttccacga
    78961 ctacgtggaa gcctatctga gcatgatcga tgaattcggc gagcagtgct cgcccaccga
    79021 ccgtgccacg ctggccgaac acttcctgtt cggcgcacgg catgaactgg ctttcgccga
    79081 ttctgctttc cggctgcaag cctggagcgt ctgaccttcc gcccggttca cgcaattctt
    79141 gagcaagggt tgaccacgcc gtcgcagact cgccgagaca acgattttcg gccaaagtta
    79201 ccgcgaggag caacggcatg gttatcacct ggcgctcgaa cagagcgcgt cgcgggggtc
    79261 aggacagaag accggcccgg agagtactcg ctctcgttct cggcctgatg gccggaatga
    79321 ccctcggtgt gtcaggcacc tcggccgccg ccgattcaca gggcggccag cggtactacc
    79381 tcgactgcgc ggccgggaac gacgcggcgg ccggtacggc gcaggggtcg gcatggcgga
    79441 ctctggacca cgtcaacgcg ctggtcttcc accctggtga ttccattctg ctacgcagcg
    79501 gcaccacctg ccaaggcacc ttttcgccaa agggttccgg taccgaggac cggccgatcg
    79561 tcgccggttc ctacggttcg ggagcgcgtc cggtcatcgt cgccgacggc gcccgcgcgg
    79621 tggtcttcct gcacaacgtg cagtactggg agctccggaa cctcgacatc tccgaccggg
    79681 cagccggcaa cggtacctcg cgcaccggga tctacgtgct gctggaggat tacggcaccg
    79741 gccatcacta cgtgatcgac ggcgtgaacg tccatcacgt ggtgggcatc gacgccacgg
    79801 ggccggcgaa cgaggacagt gcgggcatcc tgttcaaggc caccggatcc accgtggcca
    79861 ccgggttcga cgggatccag gtcacgggaa acaccgtctc cggcgtcgac ggctacggaa
    79921 tagcgacatc gtcccaatgg tcgctccgcc cgctgctcac ctccggaacg aacaccttcg
    79981 tgccgatctc ccatgtgcgg atcgccggaa accggctgtc cgatctcggc ggtgacggga
    80041 tcgtcgtaca gaacggcatc gacccgctgg tcgaaggcaa tgtgatcgac ggattcggga
    80101 agcgcgccac ggccttccac gccggaatct ggtcgtggaa ctccgaccgt ccggtgatgc
    80161 agtacaacga cgtgtcgcac ggctcctcct ctccgcctgc cttcgccttc gacgtcgaca
    80221 tcgcggctgc cggtgttctc taccagtaca actacagcca cgaaaatgcc gggttcatgc
    80281 tgctgtgcac gaatccgggc gagaagagcg ccggggcgac catccgctac aacgtcagcg
    80341 agaacgaccg gggcgcactg ttcggtacca ccgaactccc gctggtcacc aatggctgcg
    80401 gcagcgtgca gccggatgtc cgcttctaca acaatgtgat ccacaccaag tacgcgagtg
    80461 ggctgatcgg gaacttcggg gagacggctg tcgcgtacag caacaacatc ttctccggaa
    80521 agccgggcgg ttcgacgatc ggcgacccga tggcgtcctt cgaccacaac ctgtacttca
    80581 acgtcacctc cgcaccgacg gtcgacgcac acgccgtcgc cgcggacccg gcgttcgtcc
    80641 ggcccggcgc cggccccctg gggtacctgc tgaagtgcgg atcgcccgcc atcggtgcgg
    80701 gtgtcctcat cgccggtgac accggacacg acttcctggg attcccggtg ccgcacgacg
    80761 cgccgccgaa catcgggccg caccagtcac cctgcgtcca cgtctaggac acggcgcagg
    80821 gccgtcaacc gcggctcgac cggctcccca gccgtcactc acacaatcac gggacacgag
    80881 ctcgaggagg aacgccatgg atatcggggt ctgcctgccg accgccgtgc acggcgccga
    80941 cagtagtcag ttgatcgagt tcgcgcgccg cgccgaccgt ctcggatttc acagcctgac
    81001 ggtgacggac cgggtcgtct acgacaacta cgagggcatt gtgacgctcg ccgcagcagc
    81061 ggcggtcacc gagcggatca acctggtgac agcgattctg ctggccgcca ccaggcccag
    81121 cccggtggag ctggccaagc agctcgccag tctggaccgg ctctccgacg ggcggctcat
    81181 actcgggctc tccgcgggga tgcgcgagga cgactacgtg gcgaccggaa ccgactacgc
    81241 gacgcgcggg cgccgcctgg acgccatgat cgaagagatg cgcgaagtct ggcagggcag
    81301 gggcccggtt cccggtgtcg gtccccgccc caccaacggt gacatcccgt tctggggtgg
    81361 cggccactcg ccgggcggcc tgcgccgttc cgcgaagtac ggcatcggct ggatctcacc
    81421 cggtggaccg ccgcacaagt tcggcgaact ggtcgcgaac ttcgcgaagt tgtgggccga
    81481 ggagggccgc accggtacgc cgagaatggc cgccaactgc tatgtgtcgc tcggtcccgg
    81541 cggcaaggaa ctcgccaccg agcacatgct cagctactac gcctacatgg gcaaggtggc
    81601 ggagcacctc gcggcgggcg cgatcactga ggaagaccgg ctgcgccaag tggtggacgc
    81661 ctacgcggcg aacggctgtg acgagctgct gctgctgtcg gtcacggccg atcccgatca
    81721 cctggaccgg atagccgacg tggtgctgcg ctgacaacca gcgcctccgc atcacacccg
    81781 catccggccc cgacctcgta acaggagtag ttgatggaca ctgcccgcga ttcgggccgg
    81841 ccgcttcgga tcatcatcat cggtggtggc atcggcggac tgtgcctcgc ccaggggctg
    81901 aagcaggccg gtattgagga cgtcgccgtc tatgaacgcg atcagtccgc ccggggccgg
    81961 atgcaggggt accggctgag gatcagcccc gacggggagc aggcgctgcg agaggtcctg
    82021 cctccccggt tgcaggagct cctcagcgcc acctcgaacc agcgcggcga ggagggcctg
    82081 gcggcgtacg acgagcacct cgaaccgaag tgggcgccca cgttcagcga tccgcgcgga
    82141 gattcaccgg acaaggtgga cgccgtggac cgggcgacgc tgcgccggat cctgctcgcc
    82201 ggcctggacg acacagtgcg cttcggcaag cggttcaccc actgcgagca ggtgggcggc
    82261 cgcgtggtgg cgcacttcga cgacggcgac tcggacgtgg gcgatgtgct ggtcgccgcc
    82321 gacggggtga actcca
//
