LOCUS       NZ_CP048835            49413 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7766546
            Orig. end                         :: 7815959
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..49413
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /region_number="21"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..49413
                     /SMILES="NC(CS)C(=O)NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..49413
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:29413](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..29413
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     misc_feature    108..123
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.2"
                     /tool="antismash"
     gene            complement(974..2218)
                     /locus_tag="C8250_RS34760"
                     /old_locus_tag="C8250_034785"
     CDS             complement(974..2218)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="C8250_RS34760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034785"
                     /product="cytochrome P450"
                     /protein_id="WP_138357729.1"
                     /sec_met_domain="p450 (E-value: 1.2e-07, bitscore: 29.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLETMPRTAETPVLEDFHPYSDQFRQDPYPHYRRILSMGGPVYWD
                     YMEAHVVARHADATAVLADPRLTVEPPPAVAALLASVVPAALLPMQRTMLFADPPDHTR
                     LRALVRHAFTPVALDAAMARGREVACAVLDDLEPGRQFDVVDDLAYPVALRIIGETMGV
                     PAADLEMLKPWSQAMVPAADIPSRPGAVEGATEAYLGFDHYFGALSERLRVSGGQGLLM
                     PLLAAEAEGVITQAELHAMAALIFVSGHDTLVGLIANALNTLLAHPDQFDLLRSTPELA
                     GQAANEVLRFESPLQLATAGGGRWAAAPIEIAGRLIPEHSRVLTLVAAANRDPHVYQDP
                     DHFDITRPGIRHLALGHGLHYCVGAALVKAQGRMVLEELARRQLQFEPVSDRQEWLPVF
                     IQRRLIRLDLRVTGR"
     gene            complement(2269..3519)
                     /locus_tag="C8250_RS34765"
                     /old_locus_tag="C8250_034790"
     CDS             complement(2269..3519)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119: halogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="C8250_RS34765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034790"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_138357730.1"
                     /transl_table=11
                     /translation="MYDVIVVGARCAGSPTAMLLARKGHRVLVLDRAEFPSDTMSTHFM
                     HQSGLARLRSWGLLDRLAATGCPPITEAVWWYGDLPIRGSAPAYDGVAEAYAPRRIVLD
                     AMLVDAAREAGAEIREGFTVRELIIEDGTVVGVRGRSHGGQEEELRARAVVGADGHRSL
                     VARTMNAEVYKERPSITVAYYTYWTGLKRGYEVYLGNEQQVAVMPTHGDACLIVCALPN
                     AEFGRYRADVEGTYHQIIEDTCPELGKEMREHGQQMEKFTGTKDLPNFYRRPYGTGWAL
                     AGDAGFHKDPVTGQGIADAFRDADVLSTALHRVLTGTGEWDQEMANYEETRNQATAALY
                     EFTCLAATLQFSDRMRQAFTVLSYDQAEANAFLGLVAGTTSVIEFFSDEHMGGLVERSK
                     DVGDRERTLTRQAAATG"
     misc_feature    3552..3567
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.51"
                     /tool="antismash"
     gene            3724..4656
                     /locus_tag="C8250_RS34770"
                     /old_locus_tag="C8250_034795"
     CDS             3724..4656
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03619.1"
                     /locus_tag="C8250_RS34770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034795"
                     /product="TIGR03619 family F420-dependent LLM class
                     oxidoreductase"
                     /protein_id="WP_187145101.1"
                     /transl_table=11
                     /translation="MDIGISLPTVGPAGRRKYVLQVAEAADRLGFHSLWISSHVALPAE
                     RHSTCLYPRATTSDAYNWGVAWLDPIAVMGVVAGATERIRIGTHVLALPYRNPVILAGE
                     LAALDQLSEGRIDLGAGIGWMDEEFAAVGIPRRERGARTDEAIAVMRTLWSAADPVSFH
                     GRFSTVDDMWLTSRPYRPGGPPIHVGGNSDPALRRVGRLGDGWLGHEVYPEEIPPARDL
                     IHRHAEEAGRDPGTIMLSARRGLIPPFPVMNFMSDRNNLSGTPADLAETFDAYRENGIS
                     MMVLDLNLRPQEIVDTLEWLSKDVLPLLS"
     gene            4713..5594
                     /locus_tag="C8250_RS34775"
                     /old_locus_tag="C8250_034800"
     CDS             4713..5594
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS34775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_034800"
                     /product="hypothetical protein"
                     /protein_id="WP_138357732.1"
                     /transl_table=11
                     /translation="MLRPARLRRSRRVRLLNILPVVLVLLAAGAFIYASKAPQTLFSPK
                     LTAISIDQAVEQYRQHPTALREDLHLPTKMPVAPNAALAGFTAPAPGVYTYATQGQDWV
                     EYNGQKYVRPFPAVSPATVLRSSGCGWELYFQTGKEYTDGHRQCSAPGEFLCMAHISEI
                     TFGSVHRAMTHVCNPGMVQVGGKAVGPGGRQSTICYASGMDSSRIDILFKNTETVMVGG
                     KPVQAYHVELDSSVQGELNGTAVADVWFETHTGTYLKMIRKQDTSSKLPDGSKVNYRVR
                     VTYELQSLTPRI"
     gene            5736..6377
                     /locus_tag="C8250_RS34780"
                     /old_locus_tag="C8250_034805"
     CDS             5736..6377
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="C8250_RS34780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034805"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_138357733.1"
                     /transl_table=11
                     /translation="MPVPVDGETRTSGRFTGLFERCGYAVERRCAGHARSDLVSPLFGR
                     VLELSAGSGENLAHYQWATHVVAAEPSRALRARLQSNVSRSRVPVTVVDATADDLPFPD
                     ASFDAVVAILTLCSVKDQARALSEIRRVLTLDGTLVFLEHVRSRNPWVAGAQSAVTPLV
                     RHMAAGCRLNRDTVTAIGAAGFAISILDTVRPNTWTPLMSTFVRGRAYVP"
     gene            complement(6525..7526)
                     /locus_tag="C8250_RS34785"
                     /old_locus_tag="C8250_034810"
     CDS             complement(6525..7526)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644676.1"
                     /locus_tag="C8250_RS34785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034810"
                     /product="beta-ketoacyl-ACP synthase 3"
                     /protein_id="WP_138357734.1"
                     /sec_met_domain="fabH (E-value: 1.8e-81, bitscore: 272.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRAPRAVTAPNAAILGVGAYRPARVLDNDELCQVLDAAGRAVVL
                     RSGIRSRRRAAPSESLAAMAHAASAKALASAGFRPGEVDHIIVTTMSRPGGHPPVSSEL
                     AQRLPTRRATISDISAVCAGFTSALALARNAVVTEQARCVLVVGTERMLDIVDPRDRST
                     AALFGDGAGAMVVGPSRQLGIGPVSWRPEESERGLASRGEAWVSLRSQATNSWPYLRMD
                     GTQVFRWAMSELPQIAQTALDLAEVKASELDAFIPHQANQRIVDGIARALNLPRRVAIA
                     RDLVEMGDTSAASIPMAMEELLASGKAPAGGLALLLGFGAGLAHAAQVVRLP"
     gene            complement(7523..8278)
                     /locus_tag="C8250_RS34790"
                     /old_locus_tag="C8250_034815"
     CDS             complement(7523..8278)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Thioesterase (23-230). E-value: 1.2e-35.
                     Score: 115.9. Matches aSDomain:
                     nrpspksdomains_C8250_RS34790_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="C8250_RS34790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034815"
                     /product="thioesterase domain-containing protein"
                     /protein_id="WP_138357735.1"
                     /sec_met_domain="Thioesterase (E-value: 1.5e-32, bitscore:
                     112.6, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAATVRLLPPAQAQDASVHPVPDLYCFPHAGGGVPTFLPWNTAL
                     AGQVRVHAVGYPDPAPGGARSITAVASAIADRLRPGPGAIFLGHSMGSLVAFETVRELH
                     RRGVRGPQVLVVAAHAAPHLARQRPPVHTLASGSFWQEVGALGGTPPEVLRSPELRLAT
                     EPRLRADFAACETYRFTSGPPLSCRVLAYAGADDPQAGPAAMQAWQLHTLGGFSLATRP
                     GDHFFLHDDPIGLVQDVLAHAETPPWDRR"
     aSDomain        complement(7589..8209)
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34790_Thioesterase.1"
                     /evalue="1.20E-35"
                     /label="C8250_RS34790_Thioesterase.1"
                     /locus_tag="C8250_RS34790"
                     /protein_end="230"
                     /protein_start="23"
                     /score="115.9"
                     /tool="antismash"
                     /translation="DLYCFPHAGGGVPTFLPWNTALAGQVRVHAVGYPDPAPGGARSIT
                     AVASAIADRLRPGPGAIFLGHSMGSLVAFETVRELHRRGVRGPQVLVVAAHAAPHLARQ
                     RPPVHTLASGSFWQEVGALGGTPPEVLRSPELRLATEPRLRADFAACETYRFTSGPPLS
                     CRVLAYAGADDPQAGPAAMQAWQLHTLGGFSLATRPGDHFFLHD"
     CDS_motif       complement(7970..8023)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34790_0001"
                     /evalue="8.90E-06"
                     /label="NRPS-te1"
                     /locus_tag="C8250_RS34790"
                     /protein_end="103"
                     /protein_start="85"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FLGHSMGSLVAFETVREL"
     gene            complement(8275..10038)
                     /locus_tag="C8250_RS34795"
                     /old_locus_tag="C8250_034820"
     CDS             complement(8275..10038)
                     /NRPS_PKS="Domain: CAL_domain (54-488). E-value: 5.5e-90.
                     Score: 293.7. Matches aSDomain:
                     nrpspksdomains_C8250_RS34795_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="C8250_RS34795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034820"
                     /product="AMP-binding protein"
                     /protein_id="WP_138357736.1"
                     /sec_met_domain="AMP-binding (E-value: 3e-83, bitscore:
                     278.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTQVEPISSATTSSAIEPAVFFGSVTVPATLTRAALTDKGIFLV
                     DGDLTECRLTYRELHDSAQRVAAGLVADGVRPGDRVCLLSGTDEPLLRTLFGVWYAGAI
                     PVLLPLPRRRGELDGFLADIGRRVEAVDARVLGVADAYAELFRDLARPERRVAAMSDLA
                     AGGPGSAPPLPQDPQATALLQFTSGTTKSSRAVMLSHHNVLSNMAAVWHGYGVGPDEVG
                     MTWLPLNHDMGIIGLLGCVARGNDVVVQSPEDFVASPLSWLSAISRYRVSLIGAPNFAY
                     ALAGRLLRNTQRKLDLSCLKWAVNGAEPIDVESLTAFTTAAERYGMRPTVPCPVFGLAE
                     ATLCVTMLPTDTPLAVAWVDRDALEVQGRAVPVPADAPGNRRLVACGHPIPGTRLAIRA
                     EDGSDLPDGHVGEIYISGQCVTSGYWNDPRGTEEILVDGWLRTGDLGYMGEQGLVVCGR
                     RKDMIILNGRNIYPEDFEAEAESVDGIRMGNTAAFYDHATDRMILVAEGRVPAGQADAL
                     ARRLMDHLRRQLPVPPHEVLICPASTVPKTTSGKRQRGRCRELYQANSLPVLGRAARNA
                     STGAQTTGSGR"
     aSDomain        complement(8575..9876)
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34795_CAL_domain.1"
                     /evalue="5.50E-90"
                     /label="C8250_RS34795_CAL_domain.1"
                     /locus_tag="C8250_RS34795"
                     /protein_end="488"
                     /protein_start="54"
                     /score="293.7"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="TYRELHDSAQRVAAGLVADGVRPGDRVCLLSGTDEPLLRTLFGVW
                     YAGAIPVLLPLPRRRGELDGFLADIGRRVEAVDARVLGVADAYAELFRDLARPERRVAA
                     MSDLAAGGPGSAPPLPQDPQATALLQFTSGTTKSSRAVMLSHHNVLSNMAAVWHGYGVG
                     PDEVGMTWLPLNHDMGIIGLLGCVARGNDVVVQSPEDFVASPLSWLSAISRYRVSLIGA
                     PNFAYALAGRLLRNTQRKLDLSCLKWAVNGAEPIDVESLTAFTTAAERYGMRPTVPCPV
                     FGLAEATLCVTMLPTDTPLAVAWVDRDALEVQGRAVPVPADAPGNRRLVACGHPIPGTR
                     LAIRAEDGSDLPDGHVGEIYISGQCVTSGYWNDPRGTEEILVDGWLRTGDLGYMGEQGL
                     VVCGRRKDMIILNGRNIYPEDFEAEAESVDGIRMG"
     CDS_motif       complement(8614..8673)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34795_0003"
                     /evalue="6.10E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="C8250_RS34795"
                     /protein_end="475"
                     /protein_start="455"
                     /score="12.6"
                     /tool="antismash"
                     /translation="CGRRKDMIILNGRNIYPEDF"
     CDS_motif       complement(8740..8823)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34795_0002"
                     /evalue="2.10E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="C8250_RS34795"
                     /protein_end="433"
                     /protein_start="405"
                     /score="32.8"
                     /tool="antismash"
                     /translation="PDGHVGEIYISGQCVTSGYWNDPRGTEE"
     CDS_motif       complement(9439..9498)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34795_0001"
                     /evalue="2.30E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS34795"
                     /protein_end="200"
                     /protein_start="180"
                     /score="14.1"
                     /tool="antismash"
                     /translation="ALLQFTSGTTKSSRAVMLSH"
     gene            complement(10080..10925)
                     /locus_tag="C8250_RS34800"
                     /old_locus_tag="C8250_034825"
     CDS             complement(10080..10925)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.4"
                     /locus_tag="C8250_RS34800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034825"
                     /product="ABC transporter permease"
                     /protein_id="WP_138357737.1"
                     /transl_table=11
                     /translation="MTDTDVAPDTAAWRTPHGTSQSVSQNHLAGEVWMLLRRNIREALR
                     SPVIAFIFPVLFPLFAETLVASSYARVSSLESFPIQPYTAYMAPGMMLLAGMMGSGYSA
                     TALVLDVQTGFLQRLRLLNVRPSAILLSRIIFDALRVLPAAVVVLLVGLALGARLESGP
                     ASVVGLLVMCSAWSVAYGGLFYIVALTTWNPQAPLAMSPLFILLMFTSTAAMPTSLQPG
                     WLASLAHYNPFTYVTEGARALMTGPVTAHALLPAAAVLVVGIALTQGFVIPLFRRAVER
                     "
     gene            complement(10922..11875)
                     /locus_tag="C8250_RS34805"
                     /old_locus_tag="C8250_034830"
     CDS             complement(10922..11875)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="C8250_RS34805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034830"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_138357738.1"
                     /transl_table=11
                     /translation="MTYRTLTFDIPRGETFGCLGRNGAGKTTLINLLTTLETPTSGSAQ
                     VCGHDVVRERTSVRARIGASLQQVALDELMTGREHLAFIGRLAGLSTSGATARAEELID
                     LFGLGSAMDKVVAVCSGGTRRRLDLALALMRDPDVLFLDEPTTGLDPQSRRALWGWVRA
                     FAVNGGTVLLTTQYLEEADVLADRIAVMDRGRVAVLDTPRRLKARYGGKRVQVRPTDGD
                     EHLRVLAEFGPSATAGPDGVTLDAAAPGLLLKTIDRLACLGVPETAYSIEEPTLEDVFV
                     RLTGSAPATDGEAQTAAGLAALGRSLATTRGKGNRT"
     gene            11961..12792
                     /locus_tag="C8250_RS34810"
                     /old_locus_tag="C8250_034835"
                     /pseudo=""
     CDS             11961..12792
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058979.1"
                     /locus_tag="C8250_RS34810"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034835"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSDRKSYSSDVSDEQWALVEPVVTAWKAAHPSVSGHQGRYAMREI
                     VNAILYQNRSGCQWDLLPHDLPPAGAVKYYFYKWRDDGTDQTIHDLLRWQLREKKRRLA
                     DPSLIVMDTQSIRVAVGVPAATTGKDAAKRVPGRKRCLAVDVLGLVVEAVAL"
     misc_feature    12267..12269
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12789..13211
                     /locus_tag="C8250_RS34815"
                     /old_locus_tag="C8250_034840"
     CDS             12789..13211
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007498355.1"
                     /locus_tag="C8250_RS34815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034840"
                     /product="hypothetical protein"
                     /protein_id="WP_138359659.1"
                     /transl_table=11
                     /translation="MSDNPQIRNVLAYVEARENELDKQAGQLRASIEDLTARLGELDAE
                     TENLRITRKTLLNIPAPEPADDPPRPEAPDHPAYQQILAVFTDTGHPMRARDLCEALDL
                     PILPKNTEGIRSKLKRLVTRGILTEPEPGLFAQPRT"
     gene            complement(13547..15622)
                     /locus_tag="C8250_RS34820"
                     /old_locus_tag="C8250_034845"
     CDS             complement(13547..15622)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.4"
                     /locus_tag="C8250_RS34820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034845"
                     /product="MMPL family transporter"
                     /protein_id="WP_187145102.1"
                     /transl_table=11
                     /translation="MGTALRRGKWPVLVCWLLLAVALGSFANRLTSVEKTDEMSFLPRS
                     SQSTQVSAVLRTAPGGDALDAVLVYHRDSGLTATDRQRLDQERRRIVALRLPGAQQPGP
                     VHVAPDGTTAVYTIAVDRKAGDDQLKDTVKALRENAADRDGLQVRVTGAAGLQLDHAEI
                     FSGVGTTLLYATALVVAVLLLLTYRSPVLWLLPLFTVGLGLRVAQAAVYGYGSNGGTVS
                     DLSAGILTVLAFGAGTDYALLLISRYREELRVHADRHEALAEALRRSVGAITASAGTVV
                     AGMLCLLAAELNSDRGLGPVAAMGVTVVYLVTMTLLPALLALFGRWLFWPLVPRVGAVA
                     ANRTALWARIGATVAKRPRTVWAGTAAVLLVMAAALLGASTQLNPLNEFPSSVDAVTGQ
                     KLIAGSFPAGASAPTSVVVPSELAARTIAVVERTPGVNEVTATRHIGQRTEIITVLGDD
                     PYSGRALATVRTLRSRLAAEIGSQAWVGGPTATQVDTRAAAARDDAVIAPLVLGVILLI
                     LMLLLRAVLGPLLLVLTVVLSFAAAFGTSTAFFDHVMGYAGINPSIPLYVFIFLVALGV
                     DYNIFLMHRVREESAQHGTRIGMLRALEGTGGVITSAGVVLAGTFAALAVLPFVPLAEV
                     GFAVAFGVLLDAIVVRSLLVPALVLDLGDAVWWPRRSAGRASSTATGDPSPLPVTD"
     misc_feature    complement(15608..15610)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(15694..15704)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(15879..16586)
                     /locus_tag="C8250_RS34825"
                     /old_locus_tag="C8250_034850"
     CDS             complement(15879..16586)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013594.4"
                     /locus_tag="C8250_RS34825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034850"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_187145103.1"
                     /transl_table=11
                     /translation="MNGWRRGAVLAALALAAIGWSVSHLLLIRWGRDTRALHRTIERST
                     LPASPPLIEAAGPLGMLDRVVEIDDPRTTAFTYGAGRPRIAVSRLLIEELAPEQLEAVL
                     RHEEAHLRRLDPLRRSLLAVASATFWYVPLVRYWQSVQVMRQELRADRHALDACGCRAV
                     AGALLAVSREAGPDPVTAAMANPALLGARIAHLEGQTVPSPPLTWSLMLRSSLGMAAVA
                     MVAVSAIYVLGCP"
     gene            complement(16718..17098)
                     /locus_tag="C8250_RS34830"
                     /old_locus_tag="C8250_034855"
     CDS             complement(16718..17098)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006374164.1"
                     /locus_tag="C8250_RS34830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034855"
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="WP_138359303.1"
                     /transl_table=11
                     /translation="MSEPAPTGLVLGPLEVEIMNVLWSAPAPVSVRDVLDALNGTRGTP
                     LAYTTVMTVLSRLADKGAAARTKEGRGYAYTAAVADEAALAVREVIRGFGAAAVAHFVD
                     EARNAPDLMARLERLMQEGDRK"
     gene            complement(17204..17911)
                     /locus_tag="C8250_RS34835"
                     /old_locus_tag="C8250_034860"
     CDS             complement(17204..17911)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="C8250_RS34835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034860"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138359301.1"
                     /transl_table=11
                     /translation="MTTEAIQQTQTEPVRELDDMARCSHLKLLVALDNDVVRWGLCSML
                     DALPTVHQTTGCGTHREALNLLQQSPQDVVVASSALNGDLAQLSTQVHAAGGKLLLLLS
                     NAGDEAMIQAAAQYADGFLLETGLTPEVLQDALSRLLRGEMPMPTALARELLSMVRRRD
                     KAPRGLFLTPREQEALALLVDGYSNKQIARRLNISEHGAKRHVANVLAKLNCSNRTLAV
                     AMALRDGLVPQVP"
     misc_feature    complement(18110..18128)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.7"
                     /tool="antismash"
     misc_feature    18173..18189
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    18345..18361
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    complement(18513..18526)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.31"
                     /tool="antismash"
     gene            18593..19003
                     /locus_tag="C8250_RS44965"
     CDS             18593..19003
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044908.1"
                     /locus_tag="C8250_RS44965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_331284116.1"
                     /transl_table=11
                     /translation="MPVIPPAQPHPRPPFGYLRASERRFVRGDFLEPGPVFVWSRTPLP
                     LVAGIPATRLQHLFINTDIACGVSSVLDWNEFVFANVDLTLHLHRQPTGEWTGLDATTH
                     ISDHGTGTTHTQLWDEKGLIGSAAQALYVARR"
     gene            complement(19035..19700)
                     /locus_tag="C8250_RS34845"
                     /old_locus_tag="C8250_034870"
     CDS             complement(19035..19700)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (93-152). E-value: 6.3e-10. Score:
                     30.9. Matches aSDomain:
                     nrpspksdomains_C8250_RS34845_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013786.4"
                     /locus_tag="C8250_RS34845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034870"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_187145104.1"
                     /transl_table=11
                     /translation="MLQLLDDQERIRMERLSKPADRDRFSTAHCLLRVLASGYLREPAD
                     HVLIVRSCTQCGEPHGKPRVQARHGPDLEVSLSHTAGRVVVAVGDASTGVDIERVRPLK
                     NLNRIAAATLSAMEHRQLDRVPAAEQAEALLAHWTRKEAVLKALGCGLVVPPETLIVSG
                     PGEPPRVLAWPEGVAKAQMRLRMLSSPLGAGYVGAVAVSSPGDITLWERDGSEIMEQI"
     aSDomain        complement(19245..19421)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34845_ACPS.1"
                     /evalue="6.30E-10"
                     /label="C8250_RS34845_ACPS.1"
                     /locus_tag="C8250_RS34845"
                     /protein_end="152"
                     /protein_start="93"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GVDIERVRPLKNLNRIAAATLSAMEHRQLDRVPAAEQAEALLAHW
                     TRKEAVLKALGCGL"
     gene            20001..23612
                     /locus_tag="C8250_RS34850"
                     /old_locus_tag="C8250_034875"
     CDS             20001..23612
                     /NRPS_PKS="Domain: PP-binding (56-95). E-value: 3.7e-07.
                     Score: 22.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS34850_PP-binding.1"
                     /NRPS_PKS="Domain: Heterocyclization (119-416). E-value:
                     9.2e-99. Score: 322.5. Matches aSDomain:
                     nrpspksdomains_C8250_RS34850_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (585-983). E-value: 3.9e-94.
                     Score: 307.5. Matches aSDomain:
                     nrpspksdomains_C8250_RS34850_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (1090-1157). E-value: 7.6e-21.
                     Score: 66.1. Matches aSDomain:
                     nrpspksdomains_C8250_RS34850_PCP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="C8250_RS34850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034875"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_187145105.1"
                     /sec_met_domain="Condensation (E-value: 6.3e-38, bitscore:
                     129.5, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-105, bitscore:
                     352.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-09, bitscore:
                     37.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVSPAITEITTAAGSGPEAAGGTLSDSQQLQLRALCAQVSPDWD
                     ESSTDGDTPLYFESIAAAELKALIEAQFHASLPLVELIEEPTLNSLIDLISAALESGTT
                     PDDLPVLVGDVGGRFEAFGLTDVQHAYWLGRSGLFELGQVSTHLYVQFESADFDVVRAR
                     VALERLVERHEMLRAVVRGDGRQQVLEVVPPVVVGLEDLSGVEGVVAAGRVAAVRDELS
                     HEVRPADVWPLFEVRVQRLPGGVSRVHFSLDLLVADAGSVQIVLEEWALLYADPGVELA
                     PLGCSFRDYVRALEGVESSEGFERARGYWLGRIEDLPAAPELPLVVAPSGVEPRFVRRQ
                     FVLDGVRWGVLKERAASFGLTASAVLAAAYAEVLGVWSKSPRFTLNFTVADRWPLHADV
                     NRLVGDFTSVLLVEADVSGSVGFVDRARALQRQVWEGLEHRAYGGVRVLRDLAREHGAE
                     RASMPVVFTSAIGHPMGDAHGDFPPFGRLVDAISQTPQVLLDMQIIEKQTGLNVSWDAV
                     DAAFPEGVLDQAFATLKALLLRLSEQDSEAWTQVQSPLLPSGQLVVREAANGAVGVVSG
                     GLLHEGVFAAAGRWAGRDAVVWPGGRMSFGELVSRAWRIGRRLREAGVRPGEPVVVAAR
                     KGWEQIAGVLGVLASGGAYVPVDPDQPERRLHGLIHRTGTRTILTQQDLFSSTSWPDGM
                     SVWSIDDDAAWDGIPDEPLEWVQDPSDLAYVIFTSGSTGEPKGVMIDHRGALNTIIDIN
                     DRFRVTENDRVLGLSSLSFDLSVWDVFGVLAAGGAVVLPDPDGLRDPSHWADLIRVEGV
                     TIWNSVPALLELFSEYVASHGAEGVGLRLALLSGDWIAVSLPDRVRDLVPGLEVVSLGG
                     ATEASIWSIAYPIGVVDPSWRSIPYGRPLVNQSFRVVDGNLRHRPDFVAGELQIGGVGV
                     AMGYWGDPERTAASFVTDPVTGERWYRTGDLGRYLPDGTIEFLGREDFQVKIGGYRIEL
                     GEIEAALLADPQVEAAVAHAWGAPGGPRRLAAYVVPVEGAILEVDKVRAQAAEVLPAYM
                     VPAALVVLDALPLTGNGKIDRKALPDPGEAARQPYVAPATPIEQTLTGIWSELLATERI
                     GVHDNLFELGADSLLALRAVAAADTAGLHLELRDVFAHPTIATQATHTTQGRSTLPVLV
                     GDVGGRFEAFGLTDVQHAYWLGRSGLFESAVRDLMSG"
     aSDomain        20169..20285
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34850_PP-binding.1"
                     /evalue="3.70E-07"
                     /label="C8250_RS34850_PP-binding.1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="95"
                     /protein_start="56"
                     /score="22.3"
                     /tool="antismash"
                     /translation="FESIAAAELKALIEAQFHASLPLVELIEEPTLNSLIDLI"
     aSDomain        20358..21248
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34850_Heterocyclization.
                     1"
                     /evalue="9.20E-99"
                     /label="C8250_RS34850_Heterocyclization.1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="416"
                     /protein_start="119"
                     /score="322.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DLLVADA"
                     /tool="antismash"
                     /translation="EAFGLTDVQHAYWLGRSGLFELGQVSTHLYVQFESADFDVVRARV
                     ALERLVERHEMLRAVVRGDGRQQVLEVVPPVVVGLEDLSGVEGVVAAGRVAAVRDELSH
                     EVRPADVWPLFEVRVQRLPGGVSRVHFSLDLLVADAGSVQIVLEEWALLYADPGVELAP
                     LGCSFRDYVRALEGVESSEGFERARGYWLGRIEDLPAAPELPLVVAPSGVEPRFVRRQF
                     VLDGVRWGVLKERAASFGLTASAVLAAAYAEVLGVWSKSPRFTLNFTVADRWPLHADVN
                     RLVGDFTSVLLVEADV"
     aSModule        20358..23471
                     /complete
                     /domains="nrpspksdomains_C8250_RS34850_Heterocyclization.1"
                     /domains="nrpspksdomains_C8250_RS34850_AMP-binding.1"
                     /domains="nrpspksdomains_C8250_RS34850_PCP.1"
                     /locus_tags="C8250_RS34850"
                     /monomer_pairings="Cys -> Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20376..20405
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0001"
                     /evalue="3.00E-03"
                     /label="Cy1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="135"
                     /protein_start="125"
                     /score="10.3"
                     /tool="antismash"
                     /translation="DVQHAYWLGR"
     CDS_motif       20505..20558
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0002"
                     /evalue="1.40E-08"
                     /label="Cy2"
                     /locus_tag="C8250_RS34850"
                     /protein_end="186"
                     /protein_start="168"
                     /score="26.9"
                     /tool="antismash"
                     /translation="LVERHEMLRAVVRGDGRQ"
     CDS_motif       20739..20783
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0003"
                     /evalue="3.60E-05"
                     /label="Cy3"
                     /locus_tag="C8250_RS34850"
                     /protein_end="261"
                     /protein_start="246"
                     /score="16.9"
                     /tool="antismash"
                     /translation="RVHFSLDLLVADAGS"
     CDS_motif       20922..20939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0004"
                     /evalue="2.50E+01"
                     /label="Cy1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="313"
                     /protein_start="307"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="GYWLGR"
     CDS_motif       21075..21134
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0005"
                     /evalue="4.00E-08"
                     /label="Cy4"
                     /locus_tag="C8250_RS34850"
                     /protein_end="378"
                     /protein_start="358"
                     /score="25.9"
                     /tool="antismash"
                     /translation="GLTASAVLAAAYAEVLGVWS"
     CDS_motif       21186..21245
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0006"
                     /evalue="2.10E-09"
                     /label="Cy5"
                     /locus_tag="C8250_RS34850"
                     /protein_end="415"
                     /protein_start="395"
                     /score="29.4"
                     /tool="antismash"
                     /translation="HADVNRLVGDFTSVLLVEAD"
     CDS_motif       21309..21353
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0007"
                     /evalue="3.80E-06"
                     /label="afterCy5"
                     /locus_tag="C8250_RS34850"
                     /protein_end="451"
                     /protein_start="436"
                     /score="19.4"
                     /tool="antismash"
                     /translation="LEHRAYGGVRVLRDL"
     CDS_motif       21384..21413
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0008"
                     /evalue="4.50E-03"
                     /label="Cy6"
                     /locus_tag="C8250_RS34850"
                     /protein_end="471"
                     /protein_start="461"
                     /score="9.9"
                     /tool="antismash"
                     /translation="MPVVFTSAIG"
     CDS_motif       21471..21521
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0009"
                     /evalue="6.60E-06"
                     /label="Cy7"
                     /locus_tag="C8250_RS34850"
                     /protein_end="507"
                     /protein_start="490"
                     /score="19.0"
                     /tool="antismash"
                     /translation="ISQTPQVLLDMQIIEKQ"
     aSDomain        21756..22949
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34850_AMP-binding.1"
                     /evalue="3.90E-94"
                     /label="C8250_RS34850_AMP-binding.1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="983"
                     /protein_start="585"
                     /score="307.5"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="AAGRWAGRDAVVWPGGRMSFGELVSRAWRIGRRLREAGVRPGEPV
                     VVAARKGWEQIAGVLGVLASGGAYVPVDPDQPERRLHGLIHRTGTRTILTQQDLFSSTS
                     WPDGMSVWSIDDDAAWDGIPDEPLEWVQDPSDLAYVIFTSGSTGEPKGVMIDHRGALNT
                     IIDINDRFRVTENDRVLGLSSLSFDLSVWDVFGVLAAGGAVVLPDPDGLRDPSHWADLI
                     RVEGVTIWNSVPALLELFSEYVASHGAEGVGLRLALLSGDWIAVSLPDRVRDLVPGLEV
                     VSLGGATEASIWSIAYPIGVVDPSWRSIPYGRPLVNQSFRVVDGNLRHRPDFVAGELQI
                     GGVGVAMGYWGDPERTAASFVTDPVTGERWYRTGDLGRYLPDGTIEFLGREDFQVKIG"
     CDS_motif       21933..21974
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0010"
                     /evalue="5.80E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C8250_RS34850"
                     /protein_end="658"
                     /protein_start="644"
                     /score="13.3"
                     /tool="antismash"
                     /translation="LGVLASGGAYVPVD"
     CDS_motif       22167..22226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0011"
                     /evalue="4.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS34850"
                     /protein_end="742"
                     /protein_start="722"
                     /score="34.5"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGEPKGVMIDH"
     CDS_motif       22338..22373
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0012"
                     /evalue="9.60E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="C8250_RS34850"
                     /protein_end="791"
                     /protein_start="779"
                     /score="3.7"
                     /tool="antismash"
                     /translation="FGVLAAGGAVVL"
     CDS_motif       22746..22835
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0013"
                     /evalue="3.40E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="C8250_RS34850"
                     /protein_end="945"
                     /protein_start="915"
                     /score="41.8"
                     /tool="antismash"
                     /translation="PDFVAGELQIGGVGVAMGYWGDPERTAASF"
     CDS_motif       22914..22979
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0014"
                     /evalue="5.90E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C8250_RS34850"
                     /protein_end="993"
                     /protein_start="971"
                     /score="34.4"
                     /tool="antismash"
                     /translation="FLGREDFQVKIGGYRIELGEIE"
     aSDomain        23271..23471
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34850_PCP.1"
                     /evalue="7.60E-21"
                     /label="C8250_RS34850_PCP.1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="1157"
                     /protein_start="1090"
                     /score="66.1"
                     /tool="antismash"
                     /translation="EQTLTGIWSELLATERIGVHDNLFELGADSLLALRAVAAADTAGL
                     HLELRDVFAHPTIATQATHTTQ"
     CDS_motif       23538..23567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34850_0015"
                     /evalue="3.00E-03"
                     /label="Cy1"
                     /locus_tag="C8250_RS34850"
                     /protein_end="1189"
                     /protein_start="1179"
                     /score="10.3"
                     /tool="antismash"
                     /translation="DVQHAYWLGR"
     gene            complement(23728..24081)
                     /locus_tag="C8250_RS34855"
                     /old_locus_tag="C8250_034880"
     CDS             complement(23728..24081)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS34855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_034880"
                     /product="hypothetical protein"
                     /protein_id="WP_244809553.1"
                     /transl_table=11
                     /translation="MSDNPQIRNVLAYVEARENELDKQAGQLRASIEDLTARLGELDAE
                     TENLRITRKTLLNIPAPEPADDPPRPEAPDHPLTSRFSLSSPTPAIRCVLETCARHSTC
                     RSSRRTPKASGPN"
     gene            complement(24078..24907)
                     /locus_tag="C8250_RS34860"
                     /old_locus_tag="C8250_034885"
                     /pseudo=""
     CDS             complement(24078..24907)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058979.1"
                     /locus_tag="C8250_RS34860"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034885"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSDRKSYSSDVSDEQWALVEPVVTAWKAAHPSVSGHQGRYAMREI
                     VNAILYQNRSGCQWDLLPHDLPPAGAVKYYFYKWRDDGTDQTIHDLLRWQLREKKRRLA
                     DPSLIVMDTQSIRVAVGVPAATTGKDAAKRVPGRKRCLAVDVLGLVVEAVALLTSAHDN
                     AAGIALLDGVAAQMGTVRKALVDQGFKKAVVDHGEQYGIDVEIVERNPADKSFIPQAKR
                     WVVEQTNGILMFYRRLVRDYEHRLATSRSRVFWAMTSVMARRPPAPPCPPGGPR"
     misc_feature    complement(24599..24601)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            25040..29413
                     /locus_tag="C8250_RS34865"
                     /old_locus_tag="C8250_034890"
     CDS             25040..29413
                     /NRPS_PKS="Domain: Heterocyclization (1-268). E-value:
                     2.6e-78. Score: 255.4. Matches aSDomain:
                     nrpspksdomains_C8250_RS34865_Heterocyclization.1"
                     /NRPS_PKS="Domain: AMP-binding (433-831). E-value: 6e-97.
                     Score: 316.7. Matches aSDomain:
                     nrpspksdomains_C8250_RS34865_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (938-1005). E-value: 9.5e-21. Score:
                     65.8. Matches aSDomain: nrpspksdomains_C8250_RS34865_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (1016-1316). E-value:
                     3.4e-66. Score: 215.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS34865_Epimerization.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C8250_RS34865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034890"
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_244809902.1"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-107, bitscore:
                     356.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.8e-09, bitscore:
                     36.9, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 9.2e-37, bitscore:
                     125.7, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFESADFDVVRARVALERLVERHEMFAVAVVRGDGRQQVLEVVP
                     PVVVGLEDLSGVEGVVAAGRVAAVRDELSHEVRPADVWPLFEVRVQRLPGGVSRVHFSL
                     DLLVADAGSVQIVLEEWALLYADPGVELAPLGCSFRDYVRALEGVESSEGFERARGYWL
                     GRIEDLPAAPELPLVVAPSGVEPRFVRRQFVLDGVRWGVLKERAASFGLTASAVLAAAY
                     AEVLGVWSKSPRFTLNFTVADRWPLHADVNRLVGDFTSVLLVEADVSGSVGFVDRARAL
                     QRQVWEGLEHRAYGGVRVLRDLAREHGAERASMPVVFTSAIGQQIPATIPGLGRQVEAI
                     SQTPQVTLDHQVYERTDGLVTAWDCLEALFDPALLDDMFAAYQNLITSLTEDLSAWQDP
                     HTVGAPSGQLVVREAANGAVGVVSGGLLHEGVFAAAGRWAGRDAVVWPGGRMSFGELVS
                     RAWRIGRRLREAGVRPGEPVVVAARKGWEQIAGVLGVLASGGAYVPVDPDQPERRLHGL
                     IHRTGTRTILTQSSLKDMVGWPAAVDVIPVDDDSEWAQTSDEPLEWVQDPSDLAYVIFT
                     SGSTGEPKGVMIDHRGALNTIIDINDRFRVTENDRVLGLSSLSFDLSVWDVFGVLAAGG
                     ALVLPDPDGSRDPAQWAELLRREQVTVWNTVPALLELLAEHLTTHGAEGVGLRLALLSG
                     DWIAVSLPDRVRDLVPGLEVVSLGGATEASIWSIAYPIGVVDPSWRSIPYGRPLVNQSF
                     RVVDGNLRHRPDFVAGELQIGGVGVAMGYWGDPERTAASFVTDPVTGERWYRTGDLGRY
                     LPDGTIEFLGREDFQVKIGGYRIELGEIEAALLADPQVEAAVAQAWGAPGGPRRLAAYV
                     VPVEGAILEVDKVRAQAAEVLPAYMVPAALVVLDALPLTGNGKIDRKALPDPGEAARQP
                     YVAPATPIEQTLTGIWSELLATERIGVHDNLFELGADSLLALRAVAAADTAGLHLELRD
                     VFAHPTIATQATHTTQGRIGAEQGTLSGPTLMTPNQIWFLEQDLPERHHWNDASFLLSL
                     QKPLDLEPLRRATEQILEHHDGLRLRFRQEEGTWQATLAEAGTGELPLTVYAFPNLTGR
                     QQKDAVTEVAEFLQRSMNLSDGPIIRLAYFDLGERPHCLLVLGHWLAVDHYSARILLED
                     LLASYFQYSQGAAKAALPAKTTSFPQWTQALHECAKGPVTQGERDYWQSRTRGHQLHFD
                     KAEGPNRLESLRTTTLRLDHDLTDAVLSGIPTATGADILDTLCTALVQALPLADAGPEE
                     PRRTLIDLERHGRDLYFEGLSVSRTVGRFSTITPTLVEIDPLTSPAGQLAAVHSQLEAV
                     PQRGAGYGLLRHAAADPALRNAPTAQVGLNYVGQVDEVFLRSDLLSVPRMSFGEQHSSV
                     GTRFRDVDVLGYVVGRRLTFSIGYSSHYFDDDTMTRFAAAFEQKLRQLAEDARRD"
     aSDomain        25043..25843
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34865_Heterocyclization.
                     1"
                     /evalue="2.60E-78"
                     /label="C8250_RS34865_Heterocyclization.1"
                     /locus_tag="C8250_RS34865"
                     /protein_end="268"
                     /protein_start="1"
                     /score="255.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DLLVADA"
                     /tool="antismash"
                     /translation="QFESADFDVVRARVALERLVERHEMFAVAVVRGDGRQQVLEVVPP
                     VVVGLEDLSGVEGVVAAGRVAAVRDELSHEVRPADVWPLFEVRVQRLPGGVSRVHFSLD
                     LLVADAGSVQIVLEEWALLYADPGVELAPLGCSFRDYVRALEGVESSEGFERARGYWLG
                     RIEDLPAAPELPLVVAPSGVEPRFVRRQFVLDGVRWGVLKERAASFGLTASAVLAAAYA
                     EVLGVWSKSPRFTLNFTVADRWPLHADVNRLVGDFTSVLLVEADV"
     aSModule        25043..28987
                     /complete
                     /domains="nrpspksdomains_C8250_RS34865_Heterocyclization.1"
                     /domains="nrpspksdomains_C8250_RS34865_AMP-binding.1"
                     /domains="nrpspksdomains_C8250_RS34865_PCP.1"
                     /domains="nrpspksdomains_C8250_RS34865_Epimerization.1"
                     /locus_tags="C8250_RS34865"
                     /monomer_pairings="Cys -> D-Cys"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       25058..25120
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0001"
                     /evalue="3.40E-03"
                     /label="C2_DCL_024-062"
                     /locus_tag="C8250_RS34865"
                     /protein_end="27"
                     /protein_start="6"
                     /score="9.7"
                     /tool="antismash"
                     /translation="DFDVVRARVALERLVERHEMF"
     CDS_motif       25097..25153
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0002"
                     /evalue="1.90E-01"
                     /label="Cy2"
                     /locus_tag="C8250_RS34865"
                     /protein_end="38"
                     /protein_start="19"
                     /score="4.7"
                     /tool="antismash"
                     /translation="LVERHEMFAVAVVRGDGRQ"
     CDS_motif       25334..25378
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0003"
                     /evalue="4.50E-05"
                     /label="Cy3"
                     /locus_tag="C8250_RS34865"
                     /protein_end="113"
                     /protein_start="98"
                     /score="16.6"
                     /tool="antismash"
                     /translation="RVHFSLDLLVADAGS"
     CDS_motif       25670..25729
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0004"
                     /evalue="5.00E-08"
                     /label="Cy4"
                     /locus_tag="C8250_RS34865"
                     /protein_end="230"
                     /protein_start="210"
                     /score="25.7"
                     /tool="antismash"
                     /translation="GLTASAVLAAAYAEVLGVWS"
     CDS_motif       25781..25840
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0005"
                     /evalue="2.70E-09"
                     /label="Cy5"
                     /locus_tag="C8250_RS34865"
                     /protein_end="267"
                     /protein_start="247"
                     /score="29.1"
                     /tool="antismash"
                     /translation="HADVNRLVGDFTSVLLVEAD"
     CDS_motif       25904..25948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0006"
                     /evalue="4.70E-06"
                     /label="afterCy5"
                     /locus_tag="C8250_RS34865"
                     /protein_end="303"
                     /protein_start="288"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LEHRAYGGVRVLRDL"
     CDS_motif       25979..26008
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0007"
                     /evalue="5.60E-03"
                     /label="Cy6"
                     /locus_tag="C8250_RS34865"
                     /protein_end="323"
                     /protein_start="313"
                     /score="9.6"
                     /tool="antismash"
                     /translation="MPVVFTSAIG"
     CDS_motif       26057..26104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0008"
                     /evalue="8.70E-07"
                     /label="Cy7"
                     /locus_tag="C8250_RS34865"
                     /protein_end="355"
                     /protein_start="339"
                     /score="21.8"
                     /tool="antismash"
                     /translation="ISQTPQVTLDHQVYER"
     aSDomain        26339..27532
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34865_AMP-binding.1"
                     /evalue="6.00E-97"
                     /label="C8250_RS34865_AMP-binding.1"
                     /locus_tag="C8250_RS34865"
                     /protein_end="831"
                     /protein_start="433"
                     /score="316.7"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="AAGRWAGRDAVVWPGGRMSFGELVSRAWRIGRRLREAGVRPGEPV
                     VVAARKGWEQIAGVLGVLASGGAYVPVDPDQPERRLHGLIHRTGTRTILTQSSLKDMVG
                     WPAAVDVIPVDDDSEWAQTSDEPLEWVQDPSDLAYVIFTSGSTGEPKGVMIDHRGALNT
                     IIDINDRFRVTENDRVLGLSSLSFDLSVWDVFGVLAAGGALVLPDPDGSRDPAQWAELL
                     RREQVTVWNTVPALLELLAEHLTTHGAEGVGLRLALLSGDWIAVSLPDRVRDLVPGLEV
                     VSLGGATEASIWSIAYPIGVVDPSWRSIPYGRPLVNQSFRVVDGNLRHRPDFVAGELQI
                     GGVGVAMGYWGDPERTAASFVTDPVTGERWYRTGDLGRYLPDGTIEFLGREDFQVKIG"
     CDS_motif       26516..26557
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0009"
                     /evalue="7.30E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="C8250_RS34865"
                     /protein_end="506"
                     /protein_start="492"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LGVLASGGAYVPVD"
     CDS_motif       26750..26809
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0010"
                     /evalue="5.30E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS34865"
                     /protein_end="590"
                     /protein_start="570"
                     /score="34.2"
                     /tool="antismash"
                     /translation="AYVIFTSGSTGEPKGVMIDH"
     CDS_motif       26921..26956
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0011"
                     /evalue="1.90E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="C8250_RS34865"
                     /protein_end="639"
                     /protein_start="627"
                     /score="2.8"
                     /tool="antismash"
                     /translation="FGVLAAGGALVL"
     CDS_motif       27329..27418
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0012"
                     /evalue="4.20E-13"
                     /label="NRPS-A_a6"
                     /locus_tag="C8250_RS34865"
                     /protein_end="793"
                     /protein_start="763"
                     /score="41.5"
                     /tool="antismash"
                     /translation="PDFVAGELQIGGVGVAMGYWGDPERTAASF"
     CDS_motif       27497..27562
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0013"
                     /evalue="7.40E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="C8250_RS34865"
                     /protein_end="841"
                     /protein_start="819"
                     /score="34.1"
                     /tool="antismash"
                     /translation="FLGREDFQVKIGGYRIELGEIE"
     aSDomain        27854..28054
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34865_PCP.1"
                     /evalue="9.50E-21"
                     /label="C8250_RS34865_PCP.1"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1005"
                     /protein_start="938"
                     /score="65.8"
                     /tool="antismash"
                     /translation="EQTLTGIWSELLATERIGVHDNLFELGADSLLALRAVAAADTAGL
                     HLELRDVFAHPTIATQATHTTQ"
     aSDomain        28088..28987
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34865_Epimerization.1"
                     /evalue="3.40E-66"
                     /label="C8250_RS34865_Epimerization.1"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1316"
                     /protein_start="1016"
                     /score="215.3"
                     /specificity="E activity: inactive"
                     /specificity="Active site motif: HWLAVDH"
                     /tool="antismash"
                     /translation="GPTLMTPNQIWFLEQDLPERHHWNDASFLLSLQKPLDLEPLRRAT
                     EQILEHHDGLRLRFRQEEGTWQATLAEAGTGELPLTVYAFPNLTGRQQKDAVTEVAEFL
                     QRSMNLSDGPIIRLAYFDLGERPHCLLVLGHWLAVDHYSARILLEDLLASYFQYSQGAA
                     KAALPAKTTSFPQWTQALHECAKGPVTQGERDYWQSRTRGHQLHFDKAEGPNRLESLRT
                     TTLRLDHDLTDAVLSGIPTATGADILDTLCTALVQALPLADAGPEEPRRTLIDLERHGR
                     DLYFEGLSVSRTVGRFSTI"
     CDS_motif       28178..28267
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0014"
                     /evalue="3.40E-05"
                     /label="C2_starter_024-063"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1076"
                     /protein_start="1046"
                     /score="16.5"
                     /tool="antismash"
                     /translation="SLQKPLDLEPLRRATEQILEHHDGLRLRFR"
     CDS_motif       28475..28540
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0015"
                     /evalue="3.30E-04"
                     /label="NRPS-E2"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1167"
                     /protein_start="1145"
                     /score="13.4"
                     /tool="antismash"
                     /translation="LLVLGHWLAVDHYSARILLEDL"
     CDS_motif       28955..28999
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0016"
                     /evalue="2.00E-03"
                     /label="NRPS-E5"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1320"
                     /protein_start="1305"
                     /score="11.0"
                     /tool="antismash"
                     /translation="VSRTVGRFSTITPTL"
     CDS_motif       29048..29104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0017"
                     /evalue="6.20E-06"
                     /label="NRPS-E6"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1355"
                     /protein_start="1336"
                     /score="18.7"
                     /tool="antismash"
                     /translation="HSQLEAVPQRGAGYGLLRH"
     CDS_motif       29135..29179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34865_0018"
                     /evalue="3.20E+01"
                     /label="Cy7"
                     /locus_tag="C8250_RS34865"
                     /protein_end="1380"
                     /protein_start="1365"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="PTAQVGLNYVGQVDE"
     gene            29560..30423
                     /locus_tag="C8250_RS34870"
                     /old_locus_tag="C8250_034895"
     CDS             29560..30423
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017390.4"
                     /locus_tag="C8250_RS34870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034895"
                     /product="M56 family metallopeptidase"
                     /protein_id="WP_187145107.1"
                     /transl_table=11
                     /translation="MIRARGRAIRTTLFLAALSAQYIVLIVIAEFIVRLELSEEEVRPC
                     QPLLALGLLVVIKVGIATGSCLRQISLSRTLRSMVRSSSADASHTQALIDRSGLRNRVT
                     VIDEPSLVACTSGLFRTRVIISTGLVDRLTTGQLEAVLRHEESHANAADPLLYLLIDVT
                     RRMFFYLPAVCGALERLLTRRELAADAHAVEVCGVGPLAGALLIALKEQPPAGQTGIPA
                     LWPALAGPGGLLESRLEQLETGRAPLPGRLPRRSLLWTLPGVIGLSLISLWILQMCAVC
                     FGCADC"
     gene            complement(30557..30985)
                     /locus_tag="C8250_RS34875"
                     /old_locus_tag="C8250_034900"
     CDS             complement(30557..30985)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014132.4"
                     /locus_tag="C8250_RS34875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034900"
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="WP_138359439.1"
                     /transl_table=11
                     /translation="MALDVSAFERLKAVAGERKGEGLARYAEEHEGGPQGLLDEVFANM
                     REVFRPDKAKGQQADFQYCIRSGDDEYNYFITVDNGQCQTGRGTVDSPRVTMRVKLPDF
                     VRLVTGKLNSMQAFLTGKVKISGDTFYATKFEAWFERP"
     gene            complement(31023..32108)
                     /locus_tag="C8250_RS34880"
                     /old_locus_tag="C8250_034905"
     CDS             complement(31023..32108)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959043.1"
                     /locus_tag="C8250_RS34880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034905"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_138359437.1"
                     /sec_met_domain="AurF (E-value: 1.2e-12, bitscore: 46.6,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRIYTLPIEQTKWKVPSGNTTVFSWDYDEGNDRLLALYEKGKA
                     KQWNSSERIDWSIAVDLDSPDLVPDEYVPIYGSDLWDRLGTKERQEVKQHVTSWQFSQF
                     LHGEQGALICASKIVQTVPDLDSKFYAATQVMDEARHVEVFSRYLQEKVGFAYPINDSL
                     KIMLNDTISDSRWDLTYLGMQVLLEGLALAGFGVTRDQTREPLARALNAYVMQDEARHV
                     AFGRLALKDFYKELSSAELADREEFCVEACFLLRDRFLGEEIWETLDLAPTEAVAHINN
                     SEAFKLFRSLLFTRIVPTLRDIGLMGPKVIKAFTEMDVLGFQDIDIEAVMDYDEQAAEE
                     IDAQRLAQVQEAISLGAGDTE"
     gene            complement(32105..32953)
                     /locus_tag="C8250_RS34885"
                     /old_locus_tag="C8250_034910"
     CDS             complement(32105..32953)
                     /NRPS_PKS="Domain: Abhydrolase_1 (20-127). E-value:
                     2.3e-23. Score: 75.0. Matches aSDomain:
                     nrpspksdomains_C8250_RS34885_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="C8250_RS34885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034910"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_269288405.1"
                     /sec_met_domain="PF00561 (E-value: 3.2e-18, bitscore: 65.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.5e-20, bitscore:
                     73.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 8.2e-07, bitscore:
                     28.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATLTAGSWNLRVHCQGEGPTIVLLHGLMTDHRAWDGVVAALRD
                     RYRLITVDAPGHGGSPARPGAYSLEDEADALVEALGDLGVEFPVVWAGHSMGGMKALRI
                     ALRHPDAVSRLVLVSTQPYVEPERTARPYTAMVEAASSWGISVDLAEVIGRLNFHPSFL
                     AGPQGQQWVEHFTHLRGQDIDEACASVFRRGDISDQLGDIKAPSLVVHGEADIPIRIKV
                     ARAWVPLLPDAEFLEVPDCGHTPPCEQPELIAASIDAFLQRLGTGQRSTGAGALTGKGA
                     L"
     aSDomain        complement(32573..32893)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34885_Abhydrolase_1.1"
                     /evalue="2.30E-23"
                     /label="C8250_RS34885_Abhydrolase_1.1"
                     /locus_tag="C8250_RS34885"
                     /protein_end="127"
                     /protein_start="20"
                     /score="75.0"
                     /tool="antismash"
                     /translation="PTIVLLHGLMTDHRAWDGVVAALRDRYRLITVDAPGHGGSPARPG
                     AYSLEDEADALVEALGDLGVEFPVVWAGHSMGGMKALRIALRHPDAVSRLVLVSTQPYV
                     EPE"
     CDS_motif       complement(32639..32680)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS34885_0001"
                     /evalue="2.80E-03"
                     /label="NRPS-te1"
                     /locus_tag="C8250_RS34885"
                     /protein_end="105"
                     /protein_start="91"
                     /score="10.3"
                     /tool="antismash"
                     /translation="AGHSMGGMKALRIA"
     gene            complement(32950..33390)
                     /locus_tag="C8250_RS34890"
                     /old_locus_tag="C8250_034915"
     CDS             complement(32950..33390)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014132.4"
                     /locus_tag="C8250_RS34890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034915"
                     /product="SCP2 sterol-binding domain-containing protein"
                     /protein_id="WP_138359433.1"
                     /transl_table=11
                     /translation="MAVFPSGDWLDEYVARINTSPEFAEAARTFEADIAYVFEAEPELG
                     HQADIWARAGVGGGKCLWWKYDVTPQEGRESQFVLQGPYSLWKQIIQGELDPMEAMLDG
                     ELAVTGHLPTLLRYVRAANALVSIAATGTTAFADEVAPAARP"
     gene            33708..34187
                     /locus_tag="C8250_RS34895"
                     /old_locus_tag="C8250_034920"
     CDS             33708..34187
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS34895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_034920"
                     /product="hypothetical protein"
                     /protein_id="WP_138359431.1"
                     /transl_table=11
                     /translation="MEHPRAVRWSIAAGLFVEFVGFLYDTLWHDQHLSEVAIPPSKLMT
                     VHSGIYLGELLVLGIALATLALRTRRAHPQAILWAVVAGGVVQIAGSGLDMWSHAHAYE
                     KPLYHDTIYTGAAVTIIGYLLLEMVASRAARREQLPVPERLADHRSDEAKQTAER"
     gene            34243..34452
                     /locus_tag="C8250_RS34900"
                     /old_locus_tag="C8250_034925"
     CDS             34243..34452
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS34900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_034925"
                     /product="hypothetical protein"
                     /protein_id="WP_138359429.1"
                     /transl_table=11
                     /translation="MAQNQDDLTPDIGAGWVLLPQSLIDMLREERFEQGWAWLDGGPKG
                     MNAAQHEDDVPDTTPAAEVLPSTS"
     gene            34543..36528
                     /locus_tag="C8250_RS34905"
                     /old_locus_tag="C8250_034930"
     CDS             34543..36528
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035501.1"
                     /locus_tag="C8250_RS34905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034930"
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="WP_187145108.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.8e-08, bitscore:
                     33.2, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATTPPPRSGRAASEVAVPDVTSQVSSPAVGQPLLGEQRKPAK
                     EVQRLDRVIIRFAGDSGDGMQLTGDRFTSETASFGNDLSTLPNFPAEIRAPAGTLPGVS
                     SFQLHFADHDILTPGDAPNVLVAMNPAALKANIADLPRGAEIIVNTDEFTKRAMAKVGY
                     AASPLEDGSLEAYAIHPVPLTSLTVEALKDSGLARKDAERAKNMFALGLLSWMYHRPTE
                     GTEKFLRKKFATKPDIAEANVAAFRAGWNFGETTEDFAVSYEIAPASAAFPAGTYRNIS
                     GNLALSYGLVAASKQADLPLYLGSYPITPASDILHELSKHKNFGVRTFQAEDEIAAIGA
                     ALGAAFGGALAVTTTSGPGVALKSETIGLAVSLELPLLVVAIQRGGPSTGLPTKTEQAD
                     LLQAMYGRNGEAPVPIVAPATAADCFDAAIEAARIALTYRTPVFLLSDGYLANGSEPWR
                     IPDIDELPDLRVQFATGPNHTLDNGDEAFWPYKRDPQTLARPWAVPGTPGLEHRIGGIE
                     KQDGTGNISYDPANHDFMVRTRQAKIDGIAVPDVTVDDPSDESPVLLIGWGSTYGPIAA
                     AIRRLRAQGHQVAQVHLRHLNPLPANLGDILGGYRHVLVPEMNLGQLAHLLRAKYLVDA
                     QSYTQVTGLPFKSEQLADHVKETFDV"
     gene            36521..37594
                     /locus_tag="C8250_RS34910"
                     /old_locus_tag="C8250_034935"
     CDS             36521..37594
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674311.1"
                     /locus_tag="C8250_RS34910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034935"
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit beta"
                     /protein_id="WP_187145109.1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8.7e-30, bitscore:
                     102.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEIRSLSLVPKSDTKQSMKDFKTDQEVRWCPGCGDYAVLAAVQS
                     FMPELGLARENVVFVSGIGCSSRFPYYMNTYGMHSIHGRAPAIATGLASSRRDLSVWVV
                     TGDGDALSIGGNHLIHALRRNVNLKILLFNNRIYGLTKGQYSPTSEVGKITKSTPMGSL
                     DAPFNPVSLAIGAEASFVARTIDSDRKHLQSVLREAAAHPGTALVEIYQNCNIFNDGAF
                     DALKDQQTAQDALIRLEHGQPIRFGAPAEDGLGSKGVVRDLATGELKVIDVTVEGTAGV
                     LVHDSHAASPTTAFALSRLADPDTLHHTPIGVLRSVERPVYDADMSDQLERAVEEKGKG
                     DLAALLAGQDTWTVNPR"
     gene            37609..37926
                     /gene="fdxA"
                     /locus_tag="C8250_RS34915"
                     /old_locus_tag="C8250_034940"
     CDS             37609..37926
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fdxA"
                     /inference="COORDINATES: protein motif:HMM:NF045480.1"
                     /locus_tag="C8250_RS34915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034940"
                     /product="ferredoxin"
                     /protein_id="WP_138359213.1"
                     /transl_table=11
                     /translation="MTYVIAQPCVDVKDRACIDECPVDCIYEGPRKLYIHPDECVDCGA
                     CEPVCPVEAIFFETDVPSEWAPYLTADREVFAGDQPSGASDHPLTADHSVVDAEPVSEV
                     Q"
     gene            complement(38021..39874)
                     /locus_tag="C8250_RS34920"
                     /old_locus_tag="C8250_034945"
     CDS             complement(38021..39874)
                     /GO_component="GO:0042597 - periplasmic space [Evidence
                     IEA]"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017262.4"
                     /locus_tag="C8250_RS34920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034945"
                     /product="copper resistance protein CopC"
                     /protein_id="WP_138359211.1"
                     /transl_table=11
                     /translation="MTQARRPHRNEMVGKALLLLVTAACWLFTATGVASAHAALLTSDP
                     VPGSVAKVAPRQVTLVFGESVRLFDDSIRVIAPDGRRVDAGTPQNLVGEQNAGRVALRE
                     DLQPGSYTVAWRAVSADSHIISGAFVFAFGHTSATASVPAVRAAPAISMLYGTARALGY
                     VGYALTVGTAGFVLVCWPAGANHRGVRRLLLAGWITLTTATASALALSGPYQSAGTFSQ
                     MFDTSLLSGTLHTPIGGALAQRMVLLAAVGPFLWLLCSQLGRELSPLHERREEAASKQR
                     DIRRGLTAAGVVLAGAIAVNWASAGHAAEGIQVPLALLSDSLHLLSMGLWIGGLVALLV
                     TLKPSPGPKGPTAASVDRFSVLAESCVAVLVVTGIYQSWRGLGSWGAMTGSGYGRLLLL
                     KVGAVVLLVALGALSRRHLVRQRASASARSSAPSRQVVPGTVRVLERADTAPVINPDDP
                     RRLRRSVAAETAVAVIVLAVTTLLTNSAPGRSQAVAAPGSVRPADIRTAVPYDTGGAGP
                     DASGRVVVSLRSAPDTGASQLTAEVINADGRAARVAEVRMAFTLPSRDVGPLRVVLSSV
                     GAGRWTTPAVQLPFPGDWQMAVTVRSSDIDEATRTTSLRIG"
     gene            complement(39871..40572)
                     /locus_tag="C8250_RS34925"
                     /old_locus_tag="C8250_034950"
     CDS             complement(39871..40572)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019599.4"
                     /locus_tag="C8250_RS34925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034950"
                     /product="YcnI family protein"
                     /protein_id="WP_346268780.1"
                     /transl_table=11
                     /translation="MHRVPGSLFGTGVHRSPLIVTTVAAAAFLLSAPAAAAHVTVQPDH
                     AVQGSYVSVVFHVPSEQKNTTTTRVEVVLPTDHPIASVRTRPLPGWSSQVEKSSLKTPL
                     STDDGQVTETVSKVVWTGGAIGIDQFEEFELAMGPLPTAGDALVFKVLQTYGNGTVARW
                     IDQPSTTGAEPENPAPVLRLTAAPAKSPSAAAVTPASSSPDVLARVLAVLGLAAATGAA
                     ALSVVRRRGTR"
     misc_feature    40535..40550
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
     gene            complement(40577..41227)
                     /locus_tag="C8250_RS34930"
                     /old_locus_tag="C8250_034955"
     CDS             complement(40577..41227)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03083.1"
                     /locus_tag="C8250_RS34930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034955"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_187145110.1"
                     /transl_table=11
                     /translation="MPIAVAGSSCAERLLLTEQRDLIPVLRAAPVRWFAHPTACPGWNV
                     RDLLAHCSAALTRITLDQVHDFSPECNQRDVTDRQDWPISRIIDELDHGYGTAGPVISN
                     SAGQLDVIGLGEWVHAGDIRAAWDLTPAYAAAGTDDALELLARCSAQRNTPLLIAHLPD
                     RDLELGTWLPDQQYVADLVTDAETLIRLYTGRPIAERPFVLSGATAQDLVIYR"
     gene            complement(41281..42312)
                     /locus_tag="C8250_RS34935"
                     /old_locus_tag="C8250_034960"
     CDS             complement(41281..42312)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124758.1"
                     /locus_tag="C8250_RS34935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034960"
                     /product="carbohydrate kinase family protein"
                     /protein_id="WP_138359205.1"
                     /transl_table=11
                     /translation="MRLAVTGSIATDHLMTFPGRFSDQLIADQLAHVSLSFLVDSLHIR
                     RGGAAANIALGLGRLGLNPLLVAAVGGDFSDYAVWLNGNGVDTQHIRTIPDAYTARFLC
                     TTDAAQNQIASFYPGAMRHARDIDLASVLEAAGPVDLVLIAPDDPEAMLRHTRACRATG
                     TPFAADPSQQLATLDTDRVKGLVNGARYLFTNAYERALLLERTGWPESTVLERVGTWIT
                     TLSEGGVRIDRSGHTTLHVPAVPVPHVTDPTGAGDAFRAGFLAATAHGLDAGAAALLGC
                     TMAACALEAVGPQSYRATLPELTARLTQAYGPAATSELRAMLAGTNSAAESHAPEPSPV
                     SRS"
     gene            complement(42438..42677)
                     /locus_tag="C8250_RS34940"
                     /old_locus_tag="C8250_034965"
     CDS             complement(42438..42677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542386.1"
                     /locus_tag="C8250_RS34940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034965"
                     /product="acyl carrier protein"
                     /protein_id="WP_138359203.1"
                     /transl_table=11
                     /translation="MDAPLQQIKDWILKRHPEREDIPGDLDLIENRLIDSLTFVEFLFL
                     LEQLSGRSIDMDAIDIEDVRCLDVIHERYLLPVG"
     gene            complement(42619..43137)
                     /gene="acpS"
                     /locus_tag="C8250_RS34945"
                     /old_locus_tag="C8250_034970"
     CDS             complement(42619..43137)
                     /EC_number="2.7.8.7"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (16-74). E-value: 3.4e-07. Score:
                     22.1. Matches aSDomain:
                     nrpspksdomains_C8250_RS34945_ACPS.1"
                     /codon_start=1
                     /gene="acpS"
                     /inference="COORDINATES: protein motif:HMM:TIGR00556.1"
                     /locus_tag="C8250_RS34945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034970"
                     /product="holo-ACP synthase"
                     /protein_id="WP_138359201.1"
                     /transl_table=11
                     /translation="MPRDENGPGAECPPGDIGVDIMLTSRVDRMLAEHGDEVLARMLTP
                     AELGDCHRDGSLDILSVAGRLAAKEAAFKTLNTSGVVLPWLAMEVRKAPGGKPVLSLRS
                     TARRLAEQAGVSGIRISISHDGAYAVAIAAASPGSFPPPRTAPSAKENSHGRTAAADQG
                     LDPQAPSRA"
     aSDomain        complement(42916..43089)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34945_ACPS.1"
                     /evalue="3.40E-07"
                     /label="C8250_RS34945_ACPS.1"
                     /locus_tag="C8250_RS34945"
                     /protein_end="74"
                     /protein_start="16"
                     /score="22.1"
                     /tool="antismash"
                     /translation="IGVDIMLTSRVDRMLAEHGDEVLARMLTPAELGDCHRDGSLDILS
                     VAGRLAAKEAAFK"
     gene            complement(43124..43972)
                     /locus_tag="C8250_RS34950"
                     /old_locus_tag="C8250_034975"
     CDS             complement(43124..43972)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267316.1"
                     /locus_tag="C8250_RS34950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034975"
                     /product="hypothetical protein"
                     /protein_id="WP_138359199.1"
                     /transl_table=11
                     /translation="MTPLSTRSTTAAPPTGVAVLGPQATALLYLLDRAFESWGVQAGAQ
                     PMIMPPLIPVEQLAELDYYRNFPHQAVVTAPLRLNGPDAGHDPVDGGFAPQTLETARLA
                     LPSAACYGVYLHLAGQELDAPQRVTVLGRCFRREEQYEDLRRLLGFHMREIVAVGDREF
                     TEEHLRHFTAQVENFAARLELPLRKEAATDPFYDCGGSRARLQQLAPVKYEFLYEDLAI
                     ASVNVHRNFFGERLAITLNGESVFTSCVAFGLERWLSALTRRFGGWAEATAAVEQALAQ
                     G"
     gene            complement(43999..44892)
                     /locus_tag="C8250_RS34955"
                     /old_locus_tag="C8250_034980"
     CDS             complement(43999..44892)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542388.1"
                     /locus_tag="C8250_RS34955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034980"
                     /product="diiron oxygenase"
                     /protein_id="WP_274599410.1"
                     /sec_met_domain="AurF (E-value: 1.9e-32, bitscore: 111.6,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITDHAVPDRFVEILDRLGRMSVEDYYNPYRMFEWADQLPENAY
                     WMTPELITAHGTPVEDEIGVEGMKRLSRWESINFYSLNVHGIRELLIEVIRRIHTPGFE
                     VPSEFFHHFIGEENEHMWFFAEFCRRYGAGKIYSTPSIKTQDAGSAETENFLVFARILL
                     FEEIVDHYNARMADDADLHETIRQVNRIHHHDESRHIAFGRELVSLLYQRVREQAGEEQ
                     LRELEAYLKRYIVFSLQSFYNPQVYRDAGFSDPLQVRSRILADPYRRTAERKAVRKPVS
                     FFVKTGIFSDSELYAA"
     gene            complement(44951..46006)
                     /locus_tag="C8250_RS34960"
                     /old_locus_tag="C8250_034985"
     CDS             complement(44951..46006)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035272.1"
                     /locus_tag="C8250_RS34960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034985"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_346268781.1"
                     /transl_table=11
                     /translation="MNTHPAQEFQQRLVSDAAAAVRGLTVSLGDRLGLYRAMADSKPVT
                     AEELASRTGIQPMYAREWLHAQVSGGYLRTDAAGARYWLPAEHVPALADRDSDLHAAPF
                     FSALAALYTSEDSLVYAYRDGGGVGWDEHDGTLDDALARYFLPGYRAHLVQRWIPALEA
                     AEDRLKDGGRIADVGCGVGYSTFLMAEAFPAAQVRGFDYYALAIEQARDLAAQRGLPEE
                     RVDFSTAGADAFEGGPYDLVTTFNCVHDIGDPDAVARHIRSQLSTDGTWMIVEPNADPD
                     PLRNTHPAGRLFMALSAVMCLPAAAAQKGPRALGNHSGEDTLREIARSAGFTRWRKADA
                     TPVSAVYEARP"
     misc_feature    46097..46113
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
     gene            complement(46229..47053)
                     /locus_tag="C8250_RS34965"
                     /old_locus_tag="C8250_034990"
     CDS             complement(46229..47053)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542383.1"
                     /locus_tag="C8250_RS34965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034990"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_138359195.1"
                     /transl_table=11
                     /translation="MEAVSCTAQWTAAARALESERDDRLFDDPFARTLAGDTGFALLKR
                     YTGAGTVPFLALRTKYLDDQALAAVARSGARQVVFVAAGMDTRAWRLTWPEHTVIYELD
                     RPALLEAKSAQLADAPLPAGRRRRAVAVDLAGDWAGSLTDAGFQPAEPTVWVMEGLLFF
                     LPEQAVRSVLATLLRLSAPGSILAGDMASRASLTNPMARGFLSALREDGAAWQFGHDEP
                     EDFLRSCGWHTTRTLQPGEAGASYGRWPYPLIARKVRDVPRSFFFTAEPSVS"
     gene            complement(47087..47542)
                     /locus_tag="C8250_RS34970"
                     /old_locus_tag="C8250_034995"
     CDS             complement(47087..47542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267312.1"
                     /locus_tag="C8250_RS34970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_034995"
                     /product="MaoC family dehydratase"
                     /protein_id="WP_138359193.1"
                     /transl_table=11
                     /translation="MRYFEDFAAGDVHDLGSVTVTAEEIIEFGKRYDPQPFHTDPAAAE
                     GSAFGGLIASGWLTASLFMRAYVDGLLRDSACAGSPGVDEIRYHRPVCPGDTLSARLTV
                     LRTGPVLGRKDRGLVQPRCELLDDAGRQVFSMTLHSLFLRRPASAGA"
     gene            complement(47573..48793)
                     /locus_tag="C8250_RS34975"
                     /old_locus_tag="C8250_035000"
     CDS             complement(47573..48793)
                     /NRPS_PKS="Domain: Aminotran_5 (75-224). E-value: 7e-09.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_C8250_RS34975_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015034778.1"
                     /locus_tag="C8250_RS34975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_035000"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_138359191.1"
                     /sec_met_domain="Aminotran_5 (E-value: 5.3e-06, bitscore:
                     24.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGIDASKQASGLGTGLQHPQTRAIHVSAPPLRRCQPLSVPLYQS
                     SAFAFDHPDDLAEAMNGPDGAFVYSRRGNPTVRALEETVAELEGGEAALATASGMGAIS
                     AVLLSALQTGDHVIAQRCLYGGTYSLFTDLSERFGIEVSYVSGQSADEVRDLLRPTTRL
                     LYLETIANPTTRIPDLPGVLAVGRQAGLLSVVDNSFASPLLCRPLEFGADVVVHSSTKY
                     LGGHSDVTGGVAVFASRGLYEACWKHAVELGATADPFAAWLTIRGLQTLSLRMERHCAN
                     ASSLADRLAEHPTVTAVHWPGRDDHPDHVLAKRVLDGFGGVLAFDLAGGRPAGRTFLAG
                     LHLARLAPSLGGVETLVLHPASISHRELDAKELAAAGIGEGTVRVSVGLEHFDDLWGDF
                     AHALSGL"
     aSDomain        complement(48122..48568)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS34975_Aminotran_5.1"
                     /evalue="7.00E-09"
                     /label="C8250_RS34975_Aminotran_5.1"
                     /locus_tag="C8250_RS34975"
                     /protein_end="224"
                     /protein_start="75"
                     /score="27.0"
                     /tool="antismash"
                     /translation="TVRALEETVAELEGGEAALATASGMGAISAVLLSALQTGDHVIAQ
                     RCLYGGTYSLFTDLSERFGIEVSYVSGQSADEVRDLLRPTTRLLYLETIANPTTRIPDL
                     PGVLAVGRQAGLLSVVDNSFASPLLCRPLEFGADVVVHSSTKYLG"
     misc_feature    complement(48743..48745)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(48890..48905)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
ORIGIN
        1 ccgccccaag gaactcctga tccatgacca ccgcgctcaa agcgccggcg gacgccgcgt
       61 ggacgatctg cgtggccgcg aacggcaacc cctcgcggcg ggccagatcc ccggcagcga
      121 acaccccctg cacggatgtc tgctgaaagt cattgaccac cacgctgccg tcctcgaaga
      181 acgtgcagcc cagcatctcg ggcaacctgc tgccctggcg ggtgaacggc cgcaggaaca
      241 gcgcgtcgca ttccagggtg tcgccgtcgt cgaagaccac cgcgcgcagg cggcctccac
      301 gctcgtccag ccggtcgatc ggttcctcgt gcagacccat gccctgggag accatcaggc
      361 gcagtagttc ttcgtcctcg atgggagctc caccggtaca cagaacgagg tcctcgcaca
      421 gccggaacat ctgcacggcg aggcgcaacg caccgctgtc gccgcccagg acggcgacgc
      481 gccgcccgcc cgcctcgtat ccgtcgcagt acgtgcagtt gaacgcgctc accccccaga
      541 tttcggccag gcccggcaca tcgggcaatc ggtcgatcat tccggtggcg agcagtagcc
      601 gacgcccttg ggcctcgctg ccgtcctgaa aaccgacggt gaacgcgccg gctgtgccct
      661 cggctgccag gaccatgctg tcgcgcagct cgacaccgtc gtatccggcg agttccttgc
      721 gtcctgcggt gcgcagctca tcggggggca tgccgtcgcg cgtgaggaac ccgtggctgt
      781 tcggggcgct ccggttccgt ccggcgccgg cgtcgcacac cagggcggtg cgacgggagc
      841 gccccagggt cagcgcggca ctgagtccag cgggaccgcc gccgatgatg attacgtcgt
      901 gcataaaagc ctccactctt cctactacgc aaccgtagta ggaagagtgg agggtggcaa
      961 ccgttcccgc ccctcagcgg ccggtcaccc gcaggtccag gcggatcagg cggcgttgga
     1021 tgaagaccgg cagccactcc tgccggtcgc tgaccggctc gaattgcagc tgacggcgcg
     1081 ccagttcctc caggaccatg cgtccttggg ccttcaccag ggcagccccg acgcagtagt
     1141 gcaggccgtg ccccagtgcc aggtgccgga ttcccggccg ggtgatgtcg aagtgatcgg
     1201 ggtcctgata gacgtgcggg tcccggttgg ccgctgccac caaggtcagt acgcgactgt
     1261 gttccgggat gagccgtccc gcgatctcga tgggtgcggc ggcccaccga ccgccgccgg
     1321 cggtggccag ctgcaatggg ctctcgaagc gcagcacctc gttggcggcc tgccccgcca
     1381 gttctggcgt ggaacgcagc aggtcgaact gatcgggatg cgcgagcagg gtgttgaggg
     1441 cattggcgat gaggccgacc agggtgtcgt gccccgagac gaagatcagg gcagccattg
     1501 cgtggagttc ggcctgggtg atcacgccct cggcctcggc ggccagaagg ggcatgagga
     1561 gcccctggcc gccggagacc cggagtcgtt ccgacagagc gccgaagtag tggtcgaatc
     1621 ccagatatgc ctcggtggct ccctccaccg ctccgggcct tgaagggatg tcggccgccg
     1681 gaaccatcgc ctgggaccat ggcttgagca tctccagatc cgctgccgga acccccatgg
     1741 tctcgccgat gatgcgcagc gcgacggggt aggcgagatc gtcgaccaca tcgaactggc
     1801 ggcccggctc caggtcgtcc agcaccgcac aggccacctc ccggccacga gccatagcag
     1861 cgtccagtgc cacaggggtg aacgcgtgac gtaccagcgc ccgtagccgg gtgtggtccg
     1921 gcgggtcggc gaacaacatg gtgcgttgca tcggcaacag agcggccggc accaccgaag
     1981 ccaggagcgc ggccaccgcc ggcggcggtt cgaccgtcag acggggatcg gccagcaccg
     2041 cggtggcatc agcgtgccgg gccacgacat gggcctccat gtagtcccag tacaccgggc
     2101 ctcccatgga caggattcgc cggtagtgcg gatacgggtc ctggcggaac tgatcggagt
     2161 agggatggaa atcctccagg accggtgttt cggcggtccg tggcatcgtc tcgagcacgg
     2221 ggtctccctt ccaaggaggc ggggtgatga ggccgagctg ctcatcgctc agccagtcgc
     2281 ggcagcctgg cgtgtcagag tgcgctcccg gtcgccgacg tccttggagc gttccaccaa
     2341 cccgcccatg tgctcgtcgg agaagaactc gatgaccgag gtggtgccgg cgaccaggcc
     2401 caggaaggcg ttcgcctcgg cctggtcgta cgacaggacg gtgaaggcct gacgcatccg
     2461 gtcgctgaac tgcagagtcg cggccaggca ggtgaactcg tagagcgcgg cggtggcctg
     2521 gttacgggtc tcctcgtagt tggccatctc ctgatcccac tccccggtgc cggtcagtac
     2581 ccggtgcagc gcggttgaca gcacgtcggc gtcccggaag gcgtcggcga ttccctgtcc
     2641 ggtgaccgga tccttgtgga acccggcgtc cccggccagc gcccaaccgg tgccgtacgg
     2701 gcggcggtag aagttcggca ggtccttggt accggtgaac ttctccatct gctgtccgtg
     2761 ctcgcgcatc tccttgccca gttcagggca ggtgtcctcg atgatctggt ggtaggtgcc
     2821 ctccacgtcg gcgcggtagc ggccgaactc cgcgttcggc agtgcgcaga cgatcaggca
     2881 ggcgtcgccg tgcgtgggca tgaccgcgac ctgctgttca ttgcccaggt agacctcgta
     2941 accgcgcttg agcccggtcc agtacgtgta gtaggccacc gtgatcgacg ggcgctcctt
     3001 gtagacctcg gcgttcatcg tccgggcgac cagggaccgg tgcccgtccg ctccgacgac
     3061 ggcacgcgcc cgaagctcct cttcctgtcc tccgtgactg cggccgcgaa cacccaccac
     3121 ggtgccgtcc tcgatgatca gttcgcggac ggtgaagccc tcgcggatct ccgccccggc
     3181 ctcgcgggcg gcgtccacca gcatggcgtc cagcacgatg cgccgcgggg cataagcctc
     3241 cgcgacaccg tcgtaggccg gcgcgctgcc gcggatcggc aggtcgccgt accaccagac
     3301 cgcctcggtg atgggcgggc agccggtcgc ggccagtcgg tcgagcagac cccatgaccg
     3361 cagccgggcc agtccgctct ggtgcatgaa gtgggtggac atggtgtctg aagggaactc
     3421 ggcccggtcc agcaccagta cccggtgccc cttccgggcg agcagcatgg cggtggggga
     3481 gccggcacag cgggctccga ccacgatgac gtcgtacatg cagcctccgg agaactcgcg
     3541 ggtggtaatc gtccccgtaa gcgaaccggc acaccggccc gggtgaaaga cccgaccaga
     3601 ggccccgaac ggtcaccttg gggcgggccg gatcggaggc tgcgttggtg ctgctccgct
     3661 gaggctggct cacgtgacgg cgcctcaccc atggtggcag ctctgtctct tacggaggag
     3721 tccatggata tcgggatctc actgcccaca gtgggtccgg cgggccggcg caagtacgtg
     3781 ctccaggtag cggaggcagc tgaccgactc ggcttccact cactgtggat cagcagtcac
     3841 gtcgccctgc ccgccgagcg ccattccacc tgtctctacc cgcgagccac cacatccgac
     3901 gcttacaact ggggtgtcgc ctggctcgac ccgatcgccg tcatgggagt ggtcgcaggc
     3961 gcgaccgagc gcatccgcat cggcacccac gtccttgccc tgccctatcg gaatcccgtc
     4021 atcctcgccg gggaactcgc ggcgctggac caactgtcgg aggggcggat cgacctgggt
     4081 gcgggtatcg ggtggatgga cgaggagttc gccgcagtcg gcatcccgcg ccgcgagcgc
     4141 ggagctcgta ccgacgaggc cattgccgtg atgaggaccc tgtggtccgc tgccgacccg
     4201 gtgtccttcc acggccgctt cagcaccgtt gacgacatgt ggctgaccag ccggccgtat
     4261 cgtcccggcg ggccgcccat ccacgtcggt ggtaactccg acccggccct gcggcgtgtc
     4321 ggccggctgg gggacggctg gctcggccat gaggtctacc cggaggagat tcccccggct
     4381 cgtgacctga tccaccgcca tgcggaagag gccggacggg acccgggcac catcatgctc
     4441 tccgcccggc gagggctgat tccgccattc cccgtcatga acttcatgtc ggaccggaac
     4501 aacctcagcg gcactcccgc cgacctcgcg gagaccttcg acgcctatcg cgagaacggc
     4561 atttcgatga tggtcctcga cctcaatctg aggccccagg agatcgtcga caccctggaa
     4621 tggctgtcca aggacgtcct tccgctgctg tcctgaccgc cgcccgcccg ctgggagcgc
     4681 agcgggcggc acccaccacg gaaggaattc cgatgctccg tcctgccagg ctccggcgca
     4741 gccgccgtgt ccgcctcctc aacatcctgc ccgtcgtcct ggtcctgctc gccgccggcg
     4801 cattcatcta tgcctccaag gccccgcaga cgctgttctc ccccaaactc accgcgatca
     4861 gcatcgacca ggccgtggag caataccggc agcatccgac ggcgctgcgg gaggacctcc
     4921 acctgccgac caagatgccc gtcgctccca atgccgcgct ggccggcttc acagcacccg
     4981 ctccgggggt gtacacctac gccacccagg ggcaggactg ggtcgagtac aacgggcaga
     5041 agtacgtccg tccatttccc gcggtcagtc cggccacggt gctgcgctcc agcgggtgtg
     5101 gctgggagct ctacttccag acgggcaagg agtacaccga cggacaccgc cagtgcagtg
     5161 cgcccggtga attcctgtgc atggcgcata tctccgagat caccttcgga tcggtgcacc
     5221 gagcgatgac gcacgtgtgc aatcccggca tggtccaggt aggtggcaag gccgtcggcc
     5281 ctggtgggcg ccagtccacc atctgctatg cgtcgggcat ggactcttcc cgcatcgaca
     5341 ttctgttcaa gaacacagag accgtcatgg tgggcggcaa gccggtccag gcctaccacg
     5401 tcgagctgga cagctccgtc cagggcgagt tgaacggcac cgcggtggcc gacgtctggt
     5461 ttgagacaca taccggcacc tatctgaaaa tgatccgtaa gcaagacacc agctcaaagc
     5521 tccctgacgg atcgaaggtc aactacaggg tgcgcgtgac ctacgaactc cagtcgctga
     5581 cgcctcgtat ctgacatcct tgacgcccag gacccgcgga ccgtcccacg gactgcgggt
     5641 cctgaggtat cgctccaagc ggtatcggga agtgaacggg cagtagccgt cggcttcccg
     5701 gccgggggca ggatgcgaac gcggaggtgg acgccatgcc ggtgcccgtc gacggcgaaa
     5761 caagaaccag cggtcggttc accgggttgt tcgaacggtg cggctatgcc gtggaacgca
     5821 gatgcgccgg ccatgcccga tcggacttgg tgagcccgct gttcgggcgc gttctggaat
     5881 tgagtgcggg aagcggggag aatctggccc actaccaatg ggccactcac gtagtcgccg
     5941 cggaaccctc ccgggcactg cgcgcgcgtc tgcagagtaa tgtctcccgg tcgcgagtcc
     6001 ccgttacagt tgtggacgcc accgctgatg atctgccttt ccctgatgcc agtttcgacg
     6061 ccgtggtggc gatactgacc ttgtgcagcg tgaaggacca ggcccgagcg ctctccgaga
     6121 tccgccgcgt cctcaccctg gacggcacgc tggtctttct ggaacatgtg cgctcccgga
     6181 atccctgggt ggccggtgcc cagagcgcag ttactcctct ggtgcgccat atggcagccg
     6241 gctgccgcct caaccgcgat accgtcacgg ccattggtgc ggccggcttc gccatcagca
     6301 tcctcgacac ggttcgcccc aacacctgga cgccgttgat gagcaccttc gtgcgagggc
     6361 gcgcctatgt gccctgatcg gtgatcctgg gaagtcggtg acgagtggct ggcctcgcag
     6421 agggcccgcg ccgggctttt cgtaacagga acaggctgtt cagcacgagg tggagggcag
     6481 gtcccgcagc ggacctgccc tccaccacgc gctgaaccac cagctcaggg cagccgcacc
     6541 acctgggctg cgtgtgccag cccggccccg aatcccagaa gcagagccag gcctcccgca
     6601 ggagcctttc cactggccag caactcctcc atggccatgg gtatggaggc cgccgatgtg
     6661 tcacccattt cgaccagatc ccgggcgatg gccactcggc gcgggaggtt cagagcccgg
     6721 gcgatgccgt ccacgatcct ttggttggcc tggtggggga tgaaggcatc caattccgag
     6781 gccttcacct cggccaggtc aagagcggtc tgggcgatct gcgggagttc cgacatcgcc
     6841 cagcgaaaca cctgggttcc gtccatccgc aggtagggcc agctgttggt ggcctgtgac
     6901 cgcagactca cccacgcttc gccgcggctg gccagaccgc gctcggactc ctcggggcgc
     6961 cagctgactg ggcctatgcc cagctggcgg gacggcccca cgaccatggc gccggcgccg
     7021 tcgccgaaca gtgccgcagt gctgcggtcg cgtgggtcga cgatgtccag catccgctcg
     7081 gtgccgacca ccaggacgca ccgtgcctgc tcggtgacga cggcattgcg ggccagcgcc
     7141 aacgccgagg tgaagcccgc gcagacggcg gagatgtcgg agatggtcgc tcgtctggtc
     7201 ggcagccgct gggccagttc gctggacacc ggtggatggc caccgggccg gctcatcgtg
     7261 gtgacgatga tgtgatccac ttcgcccggt cggaaacctg cggaggccag cgccttggcc
     7321 gacgcggcat gcgccatggc tgcgagtgat tcgctgggag ccgccctccg acgactgcgg
     7381 atccctgagc gcagaacgac cgcccggcct gcggcatcca gcacctggca cagttcgtcg
     7441 ttgtccagca ctcgggccgg acggtaggcg cccacgccca gaatggcggc gttcggtgcc
     7501 gtgacggccc gcggagcccg cgtcaccgcc ggtcccaagg cggtgtctcg gcgtgcgcca
     7561 ggacatcctg aacgagaccg atggggtcgt cgtgcaggaa gaagtggtca cccggccggg
     7621 tggcgaggga gaagccgccc agcgtgtgca gttgccaggc ctgcatggca gcaggccctg
     7681 cctgggggtc atccgcgccg gcgtaggcca gtacgcggca gctgagcggt ggtcctgagg
     7741 tgaaccggta ggtctcacag gcggcgaagt ccgcacgcag tcgcggctcg gtcgccagcc
     7801 ggagttccgg gctgcggagc acctccgggg gcgtgccgcc gagcgccccg acctcctgcc
     7861 agaaggatcc ggacgccaag gtgtgcaccg gcggtcgctg ccgtgccaga tgaggagcgg
     7921 cgtgggcggc gaccacgagc acttgcgggc cgcgcacgcc gcgtcggtgg agctcgcgca
     7981 ctgtctcgaa ggcgaccagg ctccccatgc tgtgcccgag gaagatggca ccagggccgg
     8041 gccgcagccg gtcggcgatc gcggatgcca ccgcggtgat gctgcgggcg ccgccgggag
     8101 ccgggtcggg ataaccgacc gcgtgcaccc gcacctgccc ggccagcgcg gtgttccatg
     8161 ggaggaacgt ggggacaccg ccgcccgcat gcgggaagca gtacagatcc ggtacgggat
     8221 gtacggatgc gtcctgtgcc tgggcgggcg gtagcaggcg gaccgtggcg gcggtcatcg
     8281 cccggagccc gtcgtctgcg ccccggtaga ggcattgcgt gcggcccgcc ccagcaccgg
     8341 cagggagttc gcctggtaga gctcccgaca ccgtccgcgc tgtcgcttgc ccgaggtggt
     8401 cttgggcacg gtggaggccg gacagatcag cacctcgtgc ggaggcaccg gcagttgacg
     8461 gcgcagatga tccatcagac gccgcgcgag ggcgtcggcc tggccggccg gcacgcggcc
     8521 ctcggccacc aggatcatcc tgtcggtggc gtggtcgtag aaggcagcgg tattgcccat
     8581 ccggataccg tccacggatt cggcctccgc ttcgaagtcc tcggggtaga tgttgcggcc
     8641 attgagaatg atcatgtcct tgcggcggcc gcagaccacg aggccctgtt cgcccatgta
     8701 gcccaggtca ccggtacgca gccatccgtc gaccaggatc tcctcggttc cccgggggtc
     8761 gttccagtac ccggaggtga cgcactggcc tgagatgtag atctctccga cgtgcccgtc
     8821 ggggagatcg gatccgtcct cggcccgtat ggccagccgg gtgccgggta tcggatgacc
     8881 gcaggccacc agccggcggt tcccgggtgc gtcggccggg accgggactg cgcggccctg
     8941 gacctccagc gcgtcgcggt ccacccaggc cacggccaga ggggtatcgg tgggcagcat
     9001 ggtcacgcag agcgttgctt cggccagccc gaacacgggg catggcactg tcggccgcat
     9061 cccgtagcgt tcggcagcgg tggtgaaggc agtgaggctc tcgacgtcga taggctcggc
     9121 gccgttgacc gcccatttca ggcaggacag atcgagcttg cgctgggtgt tccgcaagag
     9181 gcgccccgcg agcgcgtagg cgaagttcgg ggcgccgatg agcgagaccc ggtagcgcga
     9241 gatcgcactg agccaggaca gggggctcgc gacgaagtcc tccggcgatt gcaccaccac
     9301 gtcgttgccc cgtgccacgc agccgagcag tccgatgatg cccatgtcgt ggttgagcgg
     9361 cagccaggtc atgccgacct catcgggccc cacaccgtag ccgtgccaga ccgctgccat
     9421 gttggacagc acgttgtggt ggctgagcat cacggcgcgc gaggacttgg tcgtccccga
     9481 ggtgaactgg agcagtgcgg tggcctgggg atcctgaggc agcggcggcg cggatccggg
     9541 tccacccgcg gccagatcac tcatggccgc gacgcggcgc tccggccgcg ccagatcccg
     9601 gaagagctcc gcataggcgt cggcgacgcc caggacccgg gcgtccaccg cctcgacgcg
     9661 ccggccgatg tccgcaagga agccgtccag ctcgcctcgc ctgcgtggca gaggtagcag
     9721 taccggaatc gccccggcgt accagacacc gaacagcgtc cgcagcagcg gttcatcggt
     9781 ccctgacagc agacagaccc ggtcgccagg tcgcaccccg tctgccacca gtccggcggc
     9841 gacgcgctga gcgctgtcat gcaattcgcg atatgtcagg cggcactcgg tgagatcgcc
     9901 gtcgaccagg aagatgccct tgtcagtgag cgcggcgcgg gtcagagtcg cgggtacggt
     9961 aacggacccg aagaacacag cgggctcgat ggcggaggaa gtcgtcgcag aagagatcgg
    10021 ctcgacctgg gtgaccatag aaactcctcg aaactccacg gacggcggtg gcgggctcct
    10081 cagcgctcga cggcgcgccg gaacagcggg atgacgaagc cttgggtgag cgcgataccg
    10141 acgacgagta cggcggcggc gggcagcagg gcatgcgctg tgaccggtcc ggtcatcagc
    10201 gctcgcgcgc cttcggtgac gtaggtgaac gggttgtagt gcgccaggga ggccagccag
    10261 cccggttgca gggacgtggg catggccgcc gtgctggtga acatcagcag gatgaacagc
    10321 ggggacatcg ccaatggggc ctgagggttc caggtggtca gcgcaacgat gtagaagagt
    10381 ccgccgtacg ccaccgacca ggcgctgcac atcaccagca gccccaccac ggacgccggg
    10441 ccggattcca gacgggctcc cagggccaga cccaccagga gcacgacgac tgcggcgggc
    10501 agtactcgca gggcgtcgaa gatgatccgg gacagcagaa tcgcggacgg gcgcacgttc
    10561 agaagccgca gccgctggag gaatccggtc tggacgtcca gcacgagagc ggtggcggag
    10621 tatccggagc ccatcatgcc ggccagcagc atcatgcccg gggccatgta ggcggtgtag
    10681 ggctggatgg gaaagctctc cagggacgag acccgggcgt acgacgaggc gacgagggtc
    10741 tcggcgaaga gcgggaacag cacgggaaag atgaaggcga tcaccgggct gcgcaaagcc
    10801 tcgcggatat tgcggcgcag cagcatccat acctcgcccg cgaggtgatt ctgggacacg
    10861 ctctgggagg tgccgtgggg tgtgcgccac gccgcggtgt ccggagctac atcggtgtcg
    10921 gtcacgtccg gtttccctta cccctggtgg tggccaggct cctgccgaga gcggcgagcc
    10981 cggcggcggt ctgtgcttcg ccgtcggtgg cgggcgcgga accggtgagg cggacgaaga
    11041 cgtcctccaa ggtcggttcc tcgatgctgt aggcggtctc gggtactccg aggcaggcga
    11101 gccggtcgat ggtcttgagc aggagaccgg gagctgccgc gtccagggtc actccgtcag
    11161 gtcctgcggt cgcagacggc ccgaactccg cgaggacacg caggtgttcg tcgccgtcgg
    11221 tggggcgcac ctggacccgt tttcctccgt agcgggcttt gagccggcga ggagtgtcca
    11281 ggaccgcgac ccggccgcgg tccatgaccg cgatccgatc ggccaggaca tcggcctcct
    11341 ccaggtactg cgtggtgagc agtacggtgc cgccgttgac ggcgaaggcg cggacccagc
    11401 cccacagggc acgccggctc tgcgggtcca ggccggtggt cggctcatcc aggaacagca
    11461 cgtccgggtc gcgcatcagg gccagagcga ggtccagccg acgacgtgta ccgccggaac
    11521 agacggccac gaccttgtcc atggcactgc cgagtccgaa caggtcgatg agttcctcag
    11581 cgcgcgcggt ggcgcccgag gtgctcagtc cggccagccg gccaatgaag gccaggtgct
    11641 cgcggccggt catcagctcg tcgagtgcga cctgttgcag ggacgcgccg atccgtgcgc
    11701 gaaccgaggt gcgctcgcgc accacatcgt gtccgcacac ctgggcggat ccgctggtgg
    11761 gcgtctccaa ggtggtgagc aggttgatca gagtggtctt accggcgccg ttccgtccca
    11821 gacagccgaa cgtctcgccg cgcggaatat cgaacgtgag agtgcggtac gtgatcttct
    11881 gtcctgctta tgatcactcg atggggtgac ggtgaagcat tattgccggt caggcgttcg
    11941 ggattcgctt gggtgacggg atgagcgatc gcaagtcgta ctcgagtgat gtctccgacg
    12001 agcagtgggc cctggtcgag cccgtggtca cggcgtggaa ggccgcgcat ccgtcggtca
    12061 gtggccacca gggcagatac gcgatgcggg agatcgtcaa cgcgatcctg taccagaacc
    12121 gcagcggctg ccagtgggac ctgctgcccc acgacctgcc gcccgccggt gcggtgaagt
    12181 actacttcta caagtggcgc gacgatggca ccgatcagac cattcatgat ctgctgcgat
    12241 ggcaactgcg ggagaagaag cggcgattag ccgacccgag cctcatcgtc atggacacgc
    12301 agagcatccg cgtggccgtc ggcgtcccgg ccgccacgac cggcaaggac gcggcgaaac
    12361 gggtgccggg gcggaagaga tgcctggccg tggacgtatt gggactcgtc gtcgaggctg
    12421 tcgccctgta aagcgtccgc acacgacaac gccgccggaa tcgcgctgct ggacggcgtg
    12481 gccgcccaga tgggcaccgt gaggaaggcc ttggtcgacc aggggttcaa gaaggccgtc
    12541 gtcgaccacg gcgagcagta cggcatcgac gtcgagatcg ttgaacgcaa cccggccgac
    12601 aagagcttca ttccgcaggc caagcggtgg gtcgtggagc agacgaacgg gatcctgatg
    12661 ttctaccggc gcctggtccg cgactacgag caccggctcg ccacctcgcg ctctcgcgtc
    12721 ttctgggcga tgacctctgt catggcccgt aagctcaccg gcgccaccct gccctcctgg
    12781 aggaccgcgt gagcgacaac ccgcagatca gaaacgtcct tgcctacgtc gaggcccgcg
    12841 agaacgaact cgacaagcag gccgggcagc tccgcgcgtc catcgaggac ctcaccgccc
    12901 gcctcggcga actcgacgcg gagaccgaga acctgcgcat cacccgcaag acgctcctga
    12961 acatcccggc accggagccc gccgacgatc cgccacggcc cgaggcgccg gaccaccccg
    13021 cttaccagca gattctcgct gtcttcaccg acaccggcca tccgatgcgt gctcgagacc
    13081 tgtgcgaggc actcgacctg ccgatcctcc cgaagaacac cgaaggcatc cggtccaaac
    13141 tgaaacgcct ggtcacacgg ggcattctca ccgaacccga acccggcctg ttcgctcagc
    13201 cccgcacctg agtaccagtc cgccccgccg accaggactc ctcacccaac cccaagcatc
    13261 aaccggacat caggtcacgt accgcactct gagatcgtcc agggcctgtg tgccgtccgg
    13321 atagaccttt cccaacgact ggagcgcgat ggccgcgttc cccatggtcg tctcctccct
    13381 ggccggccgg taggaccggc tcctggcgaa gcgagcatcg cgcgtgggcg gctacggcgc
    13441 acagtccact ccgggcggcc tttgtaagca cgaaggccga tcggacgtag tgcccgatcg
    13501 gccatgccgc acggccggaa agggccgacg tggggagaag tgaggttcag tcggtgacag
    13561 gcagcggaga gggatctccg gtcgccgtcg aggaggcgcg tcctgcgctg cggcgcggcc
    13621 accagacagc atccccgagg tcgagaacga gagccggcac cagcagcgag cggacaacga
    13681 tggcgtccag gagtacgccg aaggcaacgg cgaagccgac ttcggccagg gggacgaacg
    13741 ggaggactgc gagggccgcg aaggtaccgg cgagaaccac gccggccgag gtgatcactc
    13801 caccggtgcc ctccagcgcc cgcagcatgc cgattctggt gccgtgctgc gcgctctcct
    13861 cccgcactcg gtgcatcaag aagatgttgt agtcgacgcc gagggccacg agaaagatga
    13921 acacatacaa cgggatggac gggttgatgc cggcgtagcc catgacgtgg tcgaagaacg
    13981 ccgtactcgt gccgaatgcc gcggcgaagc tgagtacgac ggtcaacacc agcagcagcg
    14041 gtcctaggac ggcgcgcagc agcagcatga ggatcagcag gatgacaccg aggacgagcg
    14101 gggcgatgac cgcgtcatca cgcgctgccg ctgcgcgggt gtccacctgg gtcgctgtcg
    14161 gtccgcccac ccacgcctgg ctgccgattt cggccgccag ccgcgaacgc aaggtgcgga
    14221 ccgtggccaa tgcccgcccg ctgtacgggt cgtcgcccag gacggtgatg atctccgttc
    14281 gctgaccgat gtgccgcgtg gcggtcactt cgttcacccc cggggtgcgt tccacgacgg
    14341 cgatggtcct cgcggccagt tcggaaggca ccacgaccga cgtcggcgct gaggcgcctg
    14401 cggggaagct gccggcgatc agtttctggc cggtcaccgc atcgaccgag gacggaaact
    14461 cgttgagcgg attcagttgg gtggacgcgc cgagcagtgc tgccgccatc accaggagca
    14521 ccgcggcggt tcctgcccag accgtccggg gccgcttggc cactgttgcc ccgattcgcg
    14581 cccacagtgc ggtgcggttc gccgcgacgg ctcctacccg agggaccagg ggccagaaga
    14641 gccagcggcc gaacagagcc aacagcgcgg gcagcaaggt cattgtcacc aggtagacca
    14701 cggtgacgcc catggccgcc acgggaccca gaccgcggtc ggagttgagt tcggcggcca
    14761 gcagacagag catgccggcc acgaccgtgc cggccgaggc cgtgatggca cccacgctgc
    14821 gacgcagtgc ttcagccagc gcctcatggc ggtcggcgtg cacccgcaac tcctcgcggt
    14881 agcgggagat caggagcagg gcgtagtccg ttccggcgcc gaaggccagc accgtcagaa
    14941 tgcccgcgga gaggtccgac acggtgccgc cgttgcttcc gtagccgtag acggccgcct
    15001 gagcgacgcg cagtccaaga cccacggtga acagcggcag caaccagagc accgggctgc
    15061 gatacgtcag cagcagcaac acagcgacga ccagagcggt cgcgtacagc aacgtggtgc
    15121 ccacgccgga gaagatctcc gcatggtcca gctgaagccc tgctgctcct gtcacgcgca
    15181 cctggaggcc gtcgcggtcg gcggcgtttt cgcgcagtgc cttgacggtg tccttcagtt
    15241 ggtcgtcgcc cgctttccgg tcgacggcga tggtgtacac ggctgtcgtg ccgtccgggg
    15301 cgacgtgcac gggaccgggt tgctgcgcgc cgggcagtcg cagcgcgacg atccgccggc
    15361 gctcctggtc gagccgctgc cgatcggtgg cggtgagtcc gctgtcgcgg tggtagacga
    15421 ggaccgcgtc caaggcgtcc ccgccggggg cggtcctcag gaccgcactt acctgcgtcg
    15481 attgggaact gcgtggcagg aaggacatct cgtcggtctt ctcgaccgac gtcagacggt
    15541 tggcgaagga tcccagggcg acggcgagca ggagccagca caccagcacc ggccacttgc
    15601 ctcgtcgtaa ggctgtcccc aaccgagtcc gaccgtcaga agccggcagg tcatgggcgt
    15661 gggctgacgc gttgcgcggc ctggtctgta aaggagacat ggcatctcgc atccgggatg
    15721 tcgggaacga acggaccgga gaacggcccg ggagggcgac gctccatcca aactactacg
    15781 ctaccgtagt agtaaatagt gttccggaca aacgagggcc ccggcgatgc cggggctcct
    15841 cctggatcgg tctgggctcg tgcgcgagcg ggaaggcgtc aggggcagcc caggacgtag
    15901 atcgcgctga cggcgaccat ggcgaccgcc gccatcccga gggaactgcg gagcatcagg
    15961 ctccaggtca gcggagggga ggggacggtc tgcccctcca ggtgcgcgat gcgggccccc
    16021 aggagtgcgg ggtttgccat ggcagccgtc acggggtccg gtccggcctc tcgtgaaacc
    16081 gccagcaacg ccccggcgac ggctcggcag ccgcatgcgt cgagggcatg gcggtcggcc
    16141 cgcagctcct ggcgcatcac ctgaaccgac tgccagtagc ggaccagcgg aacataccaa
    16201 aaggtcgccg aggcaacggc caacaggctg cggcgtagcg ggtccaggcg ccgcaggtgt
    16261 gcttcctcgt gtcgcagtac ggcttcgagt tgttcaggag cgagttcctc gatcaacagc
    16321 cgggagacgg cgatacgggg ccggccggcg ccgtatgtga acgccgtcgt ccgtgggtcg
    16381 tcgatctcga ccacccggtc gagcattccg agggggcccg cagcctcgat cagcggcggg
    16441 gaagcgggca gggtggatcg ctcgatggtt cggtgcaggg cgcgagtgtc gcgcccccat
    16501 cggatgagga gcagatgcga gaccgaccat ccgatggccg cgagcgccag ggcggccagt
    16561 acggcaccac gcctccagcc gttcaacgcc ccggcccctc gggttgtgac gaaggagaaa
    16621 gccacgaaca tgaagaatgc ggtcccggcc aaccgcacgg ccaggcctgc cgcgggtagc
    16681 cacacgcccc attgggcacg gtgggtggag ccgccgatca cttgcggtcg ccttcttgca
    16741 tcaggcgctc cagccgggcc atgaggtctg gggcgttgcg ggcctcgtcg acgaagtgcg
    16801 cgacggcggc cgccccgaat ccgcggatca cctcgcggac cgccaatgcc gcctcgtcgg
    16861 cgaccgcggc ggtataggca tagccccggc cttccttggt gcgcgcggca gcgcccttgt
    16921 cggccagtcg ggagagcaca gtcatcacag tggtgtaggc aagcggggtt ccgcgggtgc
    16981 cgttgagggc gtcgaggacg tcccggacgg agaccggggc cggtgcactc cacagcacgt
    17041 tcatgatctc gacctcgaga gggccgagaa cgagaccagt gggagcaggt tcggacatca
    17101 catcctcaat ctactacgca agcgtggtag acgatagctc tgctcggggt ccccccgggc
    17161 cggccccttg gggaaggccg gcccggggag accccggggt gggtcacgga acctggggca
    17221 ccagaccgtc ccgcagagcc atcgcgaccg ccaaggtcct gttggagcag ttcagctttg
    17281 caagaacgtt cgcaacgtgc cgctttgccc cgtgctccga aatgttcagc cgtcgtgcga
    17341 tctgcttgtt gctgtagcca tccaccagga gcgcaagcgc ctcctgctcg cgcggagtga
    17401 ggaagagccc gcgcggcgcc ttgtccctgc gacgcaccat ggacagcagc tcgcgggcca
    17461 gggccgtcgg cattggcatc tcgccccgta gaagccggct gagggcatcc tgcaagacct
    17521 cgggagtgag acccgtctcg agcaggaacc catccgcgta ctgtgcggcg gcctggatca
    17581 tcgcttcgtc gccggcattg ctgagcagca acaacagctt tccgcccgcg gcgtgaacct
    17641 gtgtgctgag ctgtgccaaa tcaccgttga gagccgagga tgccaccact acgtcctgcg
    17701 gagactgctg caacaggttc agcgcctcgc ggtgagtccc gcaaccggtc gtctgatgca
    17761 cggtggggag agcgtcgagc atggagcaca gaccccaacg cacaacatcg ttgtcaagcg
    17821 cgacgagcag cttgaggtga ctacatcgag ccatgtcgtc cagctcgcga acgggttctg
    17881 tctgggtctg ttggatcgcc tcggtggtca tgcggtgccc ccatgcgaaa tgcggtcggg
    17941 cgtgcccggc cgttcgggta caggtggttg tgcgggttgc ggcacaggat cctggaggga
    18001 gtgctcaggg ggaacgaccg atagggcctg ctgaaccccc gtgtgcagca agtgggttga
    18061 ccgggtgtgg tgcccggtcg gcgctcgaac aagtgagcta catggtgctt ctggttctat
    18121 atatactacg accctgtagt ggtaatccag gggtccttga ccgctagagg ccaaaccccc
    18181 ctccggtatc cgtcataccg gaccaaagtc agcggccgca ggccaaacgg agggcagatc
    18241 gatggatgac gaggcgttct accgtccgct gggagacgac tccttccgtc cgaccgtctg
    18301 cgctcaaggc cctacccatc agtacggggg agccgtcgct gctttgctca tcaaggcggc
    18361 agaggactct gttgccgctc ctgggttcca actgacccga gccacatgcg acttcctggg
    18421 accggttccg atcgcggatg tcacgatcgc ggcgcacacg gcccgccaag gcgccagcct
    18481 ccaactcgtc gtcgctgaac tctctgtcgc aggcaagacg tgtgccactt tgaggggttg
    18541 gtggatgcga tccactcggc tcgacctccc ccggcaggat gaggagcggc cggtgcccgt
    18601 cataccgccc gcgcagccgc atccccgacc accgttcggc tacctccggg cctccgagcg
    18661 ccgattcgtg cgaggagact tcctcgagcc ggggccggtg ttcgtctggt cccgtacccc
    18721 gctgccgctg gtcgccggga tacctgccac tcgcctgcaa cacctgttca tcaacaccga
    18781 catcgcctgc ggtgtcagct ccgtgctcga ctggaacgaa ttcgtcttcg ccaacgtcga
    18841 tctgacgctc caccttcacc ggcaacccac cggtgaatgg accggactgg acgccacgac
    18901 gcacatcagt gaccacggca ccggcaccac ccacacccaa ctgtgggacg aaaagggcct
    18961 catcgggagt gccgctcagg ccctgtacgt cgcccgccgc tgagcgtgca gtcggcggac
    19021 gaaggcctcg tccctcagat ctgttccatg atctccgaac cgtcacgttc ccacagagtg
    19081 atgtcgccag ggctcgagac ggctaccgcc cctacatagc cggcgccaag cggactggac
    19141 agcatgcgca accgcatctg tgccttggct acaccctccg gccatgccag gactcttggg
    19201 ggctcgccag gaccggagac aatcaaggtc tcgggcggca ccaccaggcc gcagcccagg
    19261 gccttcagga ccgcttcctt gcgcgtccaa tgggcgagta gggcctcggc ctgttcggcc
    19321 gccggtaccc gatccagttg ccggtgctcc atcgccgaca gcgtcgcggc ggcgatccgg
    19381 ttcaggttct tcagcggtcg gacgcgctcg atgtccacgc cggtcgaggc atcaccgacg
    19441 gcgacgacga cgcggccggc ggtatgggac agcgagacct ccagatccgg gccatgacgc
    19501 gcctgcactc gcggtttgcc gtgcggttca ccgcattgcg tgcaacttcg cacgatcaga
    19561 acgtgatccg ccggttctcg taggtacccc gatgccagga cccgcagcag gcagtgcgcc
    19621 gtgctgaagc gatctcggtc ggcaggcttc gacagccgct ccatccgaat gcgctcctgg
    19681 tcgtccagta gctggagcat cgctggcacc gatgaacgaa ccggagccca ccacacatga
    19741 caggacccgg cgtccggccg agtcaaaccc gccatctcat tgcttcctct cccggaggtc
    19801 cgcgagcctc aatccaacac gaagaggggc agggcaggcc atagcgctcc gccgccccga
    19861 gtgagtagta gccgaccggg cagggcgccc gcacatgtga ggcatcgccc atcgccccgc
    19921 caggcggggc ttaatcctgg ggcggaactc gaccacgctg gtccgttgtg aactcgcccg
    19981 tcagccgtgg aggaatcgcc gtggacgtca gccctgccat tacggaaatc acgaccgccg
    20041 cgggatccgg gccggaagcg gctggaggca cgctctcgga ctcgcagcag cttcagttgc
    20101 gcgcactgtg cgcccaggta agtcccgact gggacgagtc cagtacggac ggcgacacgc
    20161 cgctgtactt cgaatcaatc gcggctgcag aactcaaagc cctcattgag gcccagttcc
    20221 acgccagcct tcccctcgtc gagctcatcg aagagccgac gctgaacagc ctgatcgacc
    20281 tgataagcgc cgcactggaa tccggcacga cccccgacga ccttccggtg ttggtggggg
    20341 atgtgggggg tcggtttgag gcgtttggtt tgactgatgt gcagcatgcg tattggttgg
    20401 gtcgttctgg gttgtttgag ttggggcagg tgtcgactca tttgtatgtg cagtttgagt
    20461 cggctgattt tgatgtggtg cgggcgcggg tggcgttgga gcggttggtg gagcggcacg
    20521 agatgttgcg tgcggtggtg cggggtgatg ggcggcagca ggtgttggag gtggtgccgc
    20581 cggtggtggt ggggttggag gatttgtcgg gggttgaggg tgttgtggct gcggggcggg
    20641 tggctgcggt gcgggatgag ttgtcgcatg aggtgcggcc ggctgatgtg tggccgttgt
    20701 tcgaggtgcg ggtgcagcgg ttgcctggtg gggtttcgcg ggtgcatttc agtttggatc
    20761 tgctggtggc tgatgcgggg tcggtgcaga ttgtgttgga ggagtgggcg ttgttgtatg
    20821 cggatccggg ggtggagttg gcgcctttgg gttgttcgtt ccgtgattat gtgcgggcgt
    20881 tggagggggt ggagtcttcg gaggggtttg agcgtgcgcg ggggtattgg ttgggtcgga
    20941 ttgaggattt gcctgcggcg ccggagttgc cgttggtggt tgcgccttct ggggtggagc
    21001 cgaggtttgt gcggcggcag tttgtgttgg acggggttcg gtggggggtg ttgaaggagc
    21061 gggcggcgtc gtttggtttg acggcgtctg cggtgttggc ggcggcgtat gcggaggttt
    21121 tgggggtgtg gtcgaagtcg ccgcggttca cgttgaattt tacggtggct gatcggtggc
    21181 ctttgcatgc ggatgtgaat cgtctggtgg gtgatttcac gtcggtgttg ttggtggagg
    21241 cggatgtttc gggttctgtg gggtttgtgg atcgggcgcg ggcgttgcag cgtcaggtgt
    21301 gggaggggtt ggagcaccgg gcgtatggcg gggttcgggt gttgcgggat ctggcgcgtg
    21361 agcatggtgc ggaacgggcc tccatgcccg tcgtcttcac cagcgccatc ggacatccca
    21421 tgggtgacgc gcacggagac ttccctccgt tcgggcggct cgtcgacgcc atctcccaga
    21481 cccctcaggt tctgctcgac atgcagatca ttgagaagca aaccggcctg aacgtcagct
    21541 gggacgcggt ggatgccgcc ttccccgaag gtgtgctcga ccaggctttc gccaccctga
    21601 aggccctcct tctgcgcctc tcggagcagg acagtgaggc ctggacccag gtgcagagcc
    21661 ccctcctgcc gtcggggcag ttggtggtgc gtgaggcggc taatggtgcg gtgggtgtgg
    21721 tgtcgggtgg gttgttgcat gagggggttt ttgcggctgc gggtcggtgg gcgggtcggg
    21781 atgcggtggt gtggccgggt ggtcggatgt cgttcggtga gttggtgtcg cgggcgtggc
    21841 ggatcggtcg gcggttgcgt gaggccgggg tccggccggg tgagccggtg gtggtcgcgg
    21901 cgcgtaaggg ctgggagcag attgccgggg tgctcggtgt cctggcgtcg ggtggcgcgt
    21961 atgtaccggt ggatcctgac cagcccgagc ggcgtctgca cggcctgatc caccgcaccg
    22021 gaacccgcac catcctcacc cagcaggatc tgttctccag tacgagctgg cctgacggca
    22081 tgagcgtgtg gtccatcgat gacgatgcgg cgtgggacgg catcccggac gagccgttgg
    22141 agtgggtgca ggatccgtcg gatctggcgt atgtgatctt cacgtcgggt tcgacggggg
    22201 agccgaaggg cgtgatgatc gatcaccgcg gcgccctgaa caccatcatc gacatcaacg
    22261 accgattccg ggtgacggag aacgaccggg tgttgggtct gtcgtcgctg agctttgacc
    22321 tgtcggtctg ggacgtcttc ggagtcctgg ccgccggcgg cgccgtagtt ctgcccgatc
    22381 cggacggact ccgcgacccg tcccactggg cagatctgat ccgtgtcgag ggcgtcacca
    22441 tctggaattc cgtccctgcg ctgctggaac tcttcagcga atacgtcgcc tctcatggtg
    22501 cggagggggt gggtttgcgg ttggcgttgt tgtcggggga ctggattgcg gtgtcgttgc
    22561 cggatcgggt gcgggacctg gtgcccggtt tggaggtggt gagcctgggt ggtgctacgg
    22621 aggcgtcgat ctggtcgatc gcgtatccga tcggtgtggt agatccgtcg tggcggagca
    22681 tcccgtacgg gcgtccgctg gtgaaccaga gtttccgggt ggtggacggg aatctgcggc
    22741 atcgcccgga cttcgtggcc ggcgagctgc agatcggcgg ggtcggggtc gcgatggggt
    22801 actggggcga tccggaacgg accgctgcct cgttcgtgac cgatccggtg acgggggagc
    22861 ggtggtaccg gactggggat ctgggccggt acctgccgga cggaacgatt gagttcctgg
    22921 gccgggagga cttccaggtc aagatcggcg gctaccgcat cgagctgggt gagatcgagg
    22981 ccgcgctgct ggccgacccg caggtcgaag ccgctgtggc gcatgcctgg ggggcacctg
    23041 gcgggccgcg ccgactggct gcgtatgtcg tgcccgtcga aggggcgatc ctggaggtcg
    23101 acaaggtccg ggcccaggcc gcggaggtcc tgccggcgta tatggtgccg gccgctttgg
    23161 tggtgctgga cgcgctgccc ttgacgggca acggcaagat cgaccgcaag gcgctgcccg
    23221 atccgggtga agccgcccgc cagccgtatg tggcaccggc cactccgatc gagcagaccc
    23281 tgaccggcat ctggtcggag ctgctggcca ccgaacgcat cggcgtccac gacaacctct
    23341 tcgaactcgg cgccgactcc ctcctcgccc tccgtgcggt cgccgcggcc gacaccgccg
    23401 gcctccacct cgaactccgc gacgtcttcg cccaccccac catcgccacc caagccaccc
    23461 acaccaccca aggacgcagc actcttccgg tgttggtggg ggatgtgggg ggtcggtttg
    23521 aggcgtttgg tttgactgat gtgcagcatg cgtattggtt gggtcgttct gggttgtttg
    23581 agagtgcggt acgtgacctg atgtccggtt gatgcttggg gttgggtgag gagtcctggt
    23641 cggcggggcg gactggtact caggtgcggg gctgagcgaa caggccgggt tcgggttcgg
    23701 tgagaatgcc ccgtgtgacc aggcgtttca gtttggaccg gatgccttcg gtgttcttcg
    23761 ggaggatcgg caggtcgagt gcctcgcaca ggtctcgagc acgcatcgga tggccggtgt
    23821 cggtgaagac agcgagaatc tgctggtaag cgggtggtcc ggcgcctcgg gccgtggcgg
    23881 atcgtcggcg ggctccggtg ccgggatgtt caggagcgtc ttgcgggtga tgcgcaggtt
    23941 ctcggtctcc gcgtcgagtt cgccgaggcg ggcggtgagg tcctcgatgg acgcgcggag
    24001 ctgcccggcc tgcttgtcga gttcgttctc gcgggcctcg acgtaggcaa ggacgtttct
    24061 gatctgcggg ttgtcgctca cgcggtcctc caggagggca gggtggcgcc ggtggccggc
    24121 gggccatgac agaggtcatc gcccagaaga cgcgagagcg cgaggtggcg agccggtgct
    24181 cgtagtcgcg gaccaggcgc cggtagaaca tcaggatccc gttcgtctgc tccacgaccc
    24241 accgcttggc ctgcggaatg aagctcttgt cggccgggtt gcgttcaacg atctcgacgt
    24301 cgatgccgta ctgctcgccg tggtcgacga cggccttctt gaacccctgg tcgaccaagg
    24361 ccttcctcac ggtgcccatc tgggcggcca cgccgtccag cagcgcgatt ccggcggcgt
    24421 tgtcgtgtgc ggacgtaagc agggcgacag cctcgacgac gagtcccaat acgtccacgg
    24481 ccaggcatct cttccgcccc ggcacccgtt tcgccgcgtc cttgccggtc gtggcggccg
    24541 ggacgccgac ggccacgcgg atgctctgcg tgtccatgac gatgaggctc gggtcggcta
    24601 atcgccgctt cttctcccgc agttgccatc gcagcagatc atgaatggtc tgatcggtgc
    24661 catcgtcgcg ccacttgtag aagtagtact tcaccgcacc ggcgggcggc aggtcgtggg
    24721 gcagcaggtc ccactggcag ccgctgcggt tctggtacag gatcgcgttg acgatctccc
    24781 gcatcgcgta tctgccctgg tggccactga ccgacggatg cgcggccttc cacgccgtga
    24841 ccacgggctc gaccagggcc cactgctcgt cggagacatc actcgagtac gacttgcgat
    24901 cgctcatccc gtcacccaag cgaatcccga acgcctgacc ggcaataatg cttcaccgtc
    24961 accccatcga gtgatcataa gcaggacaga agatcacgta ccgcactctg agttggggca
    25021 ggtgtcgact catttgtatg tgcagtttga gtcggctgat tttgatgtgg tgcgggcgcg
    25081 ggtggcgttg gagcggttgg tggagcggca cgagatgttt gcggtggcgg tggtgcgggg
    25141 tgatgggcgg cagcaggtgt tggaggtggt gccgccggtg gtggtggggt tggaggattt
    25201 gtcgggggtt gagggtgttg tggctgcggg gcgggtggct gcggtgcggg atgagttgtc
    25261 gcatgaggtg cggccggctg atgtgtggcc gttgttcgag gtgcgggtgc agcggttgcc
    25321 tggtggggtt tcgcgggtgc atttcagttt ggatctgctg gtggctgatg cggggtcggt
    25381 gcagattgtg ttggaggagt gggcgttgtt gtatgcggat ccgggggtgg agttggcgcc
    25441 tttgggttgt tcgttccgtg attatgtgcg ggcgttggag ggggtggagt cttcggaggg
    25501 gtttgagcgt gcgcgggggt attggttggg tcggattgag gatttgcctg cggcgccgga
    25561 gttgccgttg gtggttgcgc cttctggggt ggagccgagg tttgtgcggc ggcagtttgt
    25621 gttggacggg gttcggtggg gggtgttgaa ggagcgggcg gcgtcgtttg gtttgacggc
    25681 gtctgcggtg ttggcggcgg cgtatgcgga ggttttgggg gtgtggtcga agtcgccgcg
    25741 gttcacgttg aattttacgg tggctgatcg gtggcctttg catgcggatg tgaatcgtct
    25801 ggtgggtgat ttcacgtcgg tgttgttggt ggaggcggat gtttcgggtt ctgtggggtt
    25861 tgtggatcgg gcgcgggcgt tgcagcgtca ggtgtgggag gggttggagc accgggcgta
    25921 tggcggggtt cgggtgttgc gggatctggc gcgtgagcat ggtgcggaac gggcctccat
    25981 gcccgtcgtc ttcaccagcg ccatcggaca gcagatcccc gcaaccatcc ccggtctggg
    26041 caggcaggtc gaagccatct cccagacccc ccaggtcacc ctcgaccacc aggtctatga
    26101 acgcactgac ggcctggtca ctgcgtggga ctgcctggag gccctcttcg accccgctct
    26161 tctcgacgac atgttcgccg cgtaccagaa cctcatcacc tccctcaccg aagacttgtc
    26221 ggcgtggcag gaccctcaca ccgtcggcgc gccgtcgggg cagttggtgg tgcgtgaggc
    26281 ggctaatggt gcggtgggtg tggtgtcggg tgggttgttg catgaggggg tttttgcggc
    26341 tgcgggtcgg tgggcgggtc gggatgcggt ggtgtggccg ggtggtcgga tgtcgttcgg
    26401 tgagttggtg tcgcgggcgt ggcggatcgg tcggcggttg cgtgaggccg gggtccggcc
    26461 gggtgagccg gtggtggtcg cggcgcgtaa gggctgggag cagattgccg gggtgctcgg
    26521 tgtcctggcg tcgggtggcg cgtatgtacc ggtggatcct gaccagcccg agcggcgtct
    26581 gcacggcctg atccaccgca ccggaacccg caccatcctc acccaaagct cgctcaagga
    26641 tatggtcggc tggccggcgg ccgtagacgt tatcccggtg gacgacgact ccgagtgggc
    26701 ccagacctcc gacgagccgt tggagtgggt gcaggatccg tcggatctgg cgtatgtgat
    26761 cttcacgtcg ggttcgacgg gggagccgaa gggcgtgatg atcgatcacc gcggcgccct
    26821 caacaccatc atcgacatca atgaccgatt ccgggtgacg gagaacgacc gggtgttggg
    26881 tctgtcgtcg ctgagcttcg acctgtcggt ctgggacgtc ttcggagtcc tggccgccgg
    26941 tggcgccctg gtcctgcccg accctgacgg ttcccgtgat ccagcccagt gggcggagtt
    27001 gctccgccgg gagcaggtga ccgtatggaa caccgtcccc gcacttttgg aactcctggc
    27061 ggagcacctg acaacccatg gtgcggaggg ggtgggtttg cggttggcgt tgttgtccgg
    27121 cgattggatt gcggtgtcgt tgccggatcg ggtgcgggac ctggtgcccg gtttggaggt
    27181 ggtgagcctg ggtggtgcta cggaggcgtc gatctggtcg atcgcgtatc cgatcggtgt
    27241 ggtggatccg tcgtggcgga gcatcccgta cgggcgtccg ctggtgaacc agagtttccg
    27301 ggtggtggac gggaatctgc ggcatcgccc ggacttcgtg gccggcgagc tgcagatcgg
    27361 cggggtcggg gtcgcgatgg ggtactgggg cgatccggaa cggaccgctg cctcgttcgt
    27421 gaccgatccg gtgacggggg agcggtggta ccggactggg gatctgggcc ggtacctgcc
    27481 ggacggaacg attgagttcc tgggccggga ggacttccag gtcaagatcg gcggctaccg
    27541 catcgagctg ggtgagatcg aggccgcgct gctggccgac ccgcaggtcg aagccgccgt
    27601 cgcacaggcc tggggagcac ctggcggccc gcgccgactg gctgcctatg tcgtgcccgt
    27661 cgaaggggcg atcctggagg tcgacaaggt ccgggcccag gccgcggagg tcctgccggc
    27721 gtatatggtg ccggccgctt tggtggtgct ggacgcgctg cccttgacgg gcaacggcaa
    27781 gatcgaccgc aaggcgctgc ccgatccggg tgaagccgcc cgccagccgt atgtggcacc
    27841 ggccactccg atcgagcaga ccctgaccgg catctggtcg gagctgctgg ccaccgaacg
    27901 catcggcgtc cacgacaacc tcttcgaact cggcgccgac tccctcctcg ccctccgtgc
    27961 ggtcgccgcg gccgacaccg ccggcctcca cctcgaactc cgcgacgtct tcgcccaccc
    28021 caccatcgcc acccaagcca cccacaccac ccaaggacgt atcggagcgg aacagggaac
    28081 gctgtccgga ccgacactca tgacgcccaa tcagatctgg ttcctcgaac aggatctgcc
    28141 cgagcgccac cactggaacg acgcgtcctt cctcctctcg ctgcagaagc ctctcgatct
    28201 ggagccactg cggcgagcca ccgaacagat tcttgagcac cacgacggcc tgcggctgcg
    28261 gttccggcag gaagagggca cctggcaggc aaccttggcc gaagcaggca ccggggaact
    28321 ccccctcacc gtctacgcct ttccaaatct gacaggacgt cagcaaaagg acgccgtcac
    28381 agaggtcgct gagtttctgc agcgcagcat gaacctctct gacggcccca tcatccggtt
    28441 ggcctacttc gacctgggcg aacgcccaca ctgcctgttg gtgctcggcc actggctcgc
    28501 ggtcgaccac tactcggcgc ggatcctgct ggaggacctg ctcgcgtcct acttccagta
    28561 ctcccagggc gcagccaaag ccgcccttcc ggcaaagacc acctcgttcc cgcagtggac
    28621 ccaggcgctg cacgagtgcg cgaagggccc cgtcacgcag ggcgagcgtg actactggca
    28681 gagccgtacc aggggacacc aactgcattt cgacaaggca gagggcccca accgactgga
    28741 aagtctgcga acaacgaccc tacgactgga ccacgacctg accgatgcgg tgctctccgg
    28801 cattcccacc gccaccggcg ccgacatcct ggacacgctg tgcacggcgc tcgtccaggc
    28861 gctgccactg gcggacgccg gccccgagga gccccggcgg accctgatcg atctggagcg
    28921 gcacggccgt gatctctact tcgaggggct gtccgtctcc cgcaccgtcg gccgcttctc
    28981 cactattacc cccaccctcg tcgagatcga tcccctgacc tcgccggccg gccagctggc
    29041 agcagtccac agccaactgg aggccgttcc gcagcggggt gccggctatg gactgctccg
    29101 ccacgcggca gccgatcccg ctcttcggaa cgcccccaca gcccaggtcg gcctcaacta
    29161 cgtcggacag gtcgatgaag tgtttcttcg gtcggatctg ctgagcgtgc cgcggatgtc
    29221 cttcggagag cagcacagca gcgtcgggac gcgttttcgc gacgtggacg tcctcggcta
    29281 cgtcgtcgga cgccgcctca ccttctccat cggctacagc tcgcactatt tcgacgacga
    29341 caccatgacg cggttcgccg cggcgttcga gcagaagctg cgacagctcg ccgaagacgc
    29401 acgtcgcgac tgatccaccc gccctttcgg gccccactgg tgaggcgtcc ttgatggaca
    29461 cctcaccagt ggggaggatg agcacaaagg gactaccgca gccggcctcg gaacgctctg
    29521 tccttctgcg gccggctctc tgccacgggg gccagagcat tgattcgtgc acggggtcgc
    29581 gccatccgca ccacgctctt ccttgccgcg ctgtcggcgc agtacatcgt cctgatcgtg
    29641 atcgcagagt tcattgtgcg gctggaactg tcagaggaag aggtcagacc gtgccaaccg
    29701 ctactggctc ttgggctgct ggtcgtcatc aaggtgggta tcgccaccgg cagctgcttg
    29761 cgccagatat cgctgagcag gactctgcgg tcaatggtgc ggagctcttc ggccgacgct
    29821 tcgcacacgc aggcgctcat cgaccgttca ggactgcgga accgggtgac cgtcatcgac
    29881 gaaccgtccc tcgtggcctg cacgagcgga ctgttccgca cacgggtcat catcagtact
    29941 ggtctggtgg accgtcttac gactggtcag ctcgaagcgg tgctgcggca cgaggagagt
    30001 cacgccaatg cggcggaccc gctgctgtat ctgctgatcg acgtcacccg acgcatgttc
    30061 ttctatcttc ccgcggtctg cggcgccctg gagcggctgc tcacccgtcg ggaacttgcc
    30121 gctgacgcgc acgcggtgga ggtctgtggg gtggggccgc tggccggcgc actcctgatc
    30181 gcactcaagg aacagccccc ggctggccag accgggattc cggccttgtg gcctgccctc
    30241 gccggtccgg gtgggctgct cgaaagccgg ctggagcagt tggagaccgg tcgtgcgccg
    30301 ctgcctggcc gcctgccgcg tcgcagcctg ttgtggacgc tgcccggagt tatcgggctg
    30361 agcctgatca gcttgtggat tctacagatg tgcgcagtct gcttcggatg cgcagactgc
    30421 tgaacacgtt cgtaagagcg tgcccggtac cggcccagga catggacctg ccgccgcatg
    30481 gaacggacgg ggggcacgtc ccatacggcg gcaggagaag aagggggcgc ccgcaaagcg
    30541 ggcaccccgg gagaactcag ggccgctcga accaggcctc gaacttggtg gcgtagaagg
    30601 tgtcaccgga gatcttgacc ttgccggtca ggaacgcctg catgctgttg agcttgcccg
    30661 tcaccaggcg cacgaaatcg ggcagcttca ccctcatcgt cacccgcggg gaatccaccg
    30721 tcccacggcc ggtctggcac tggccgttgt cgaccgtgat gaagtagttg tactcgtcgt
    30781 cgccggagcg aatgcagtac tggaagtccg cctgctgtcc cttcgccttg tcgggacgga
    30841 agacctcgcg catgttggcg aacacctcat cgagcaggcc ctgcgggccg ccctcgtgct
    30901 cttcggcgta gcgcgcgaga ccctcgccct tgcgctctcc ggccacggcc ttgagccgct
    30961 cgaatgctga tacgtccaat gccatcgttt gtactcctga ttcctggctc gcggatcgct
    31021 gtctactcgg tgtcgccggc gccgaggctg atggcctcct ggacctgagc cagccgctgc
    31081 gcgtcgatct cctccgcggc ctgctcgtcg tagtccatga ccgcctcgat gtcgatgtcc
    31141 tggaagccca ggacatccat ctcggtgaag gccttgatca ccttggggcc catcagcccg
    31201 atgtcgcgca gggtcggcac gatccgggtg aacagcaggg accggaagag cttgaacgcc
    31261 tcgctgttgt tgatgtgggc gacagcttcc gtgggagcca gatccagtgt ctcccagatc
    31321 tcctcgccca ggaaccggtc ccggagaagg aagcaggcct ccacacagaa ttcctcgcgg
    31381 tcggcgagtt ccgcggagga cagttccttg tagaagtcct tgagcgcgag ccggccgaag
    31441 gcgacatgcc gtgcttcgtc ctgcatcacg taggcgttca gcgcacgggc gagcggctcg
    31501 cgggtctggt cccgggtgac tccgaagcct gccagcgcga gcccttcgag cagcacctgc
    31561 atgcccaggt aggtcaggtc ccaccggctg tcggagatcg tgtcgttgag catgatcttg
    31621 aggctgtcgt tgatcggata ggcgaagccg accttctcct gcaggtagcg ggagaagacc
    31681 tcgacatgcc gtgcctcgtc catgacctga gtggccgcgt agaacttgga gtccaggtcc
    31741 gggaccgtct gcacgatctt ggaggcgcag atgagggcgc cctgctcacc gtggaggaat
    31801 tgggagaact gccaggacgt cacatgttgc ttgacctcct gacgctcctt ggtgcccagc
    31861 ctgtcccaca ggtcggagcc gtagatcggc acgtactcgt ccggaaccag gtccgggctg
    31921 tcgaggtcga cggcgatgga ccagtcgata cgctccgagg agttccactg tttggccttg
    31981 cccttctcgt acagggccag cagcctgtcg ttgccttcgt cgtagtccca ggagaagacg
    32041 gtggtgttcc cgctgggaac cttccacttc gtctgttcaa tgggcagagt gtagatccgg
    32101 gtactcacag tgctcctttt ccggtcagcg cgcctgcgcc cgttgaccgc tgtccagtgc
    32161 cgaggcgttg aaggaaggcg tcaatcgacg cggcaatcag ttcgggctgc tcgcacgggg
    32221 gcgtgtggcc gcagtccggt acctccagga actcggcatc cggcagcagc gggacccatg
    32281 cacgggcgac cttgatgcgg atcggaatgt ccgcctcgcc gtgcaccacc aggctcgggg
    32341 ccttgatgtc ccccagttgg tcggagatgt ccccgcgccg gaataccgag gcgcaggcct
    32401 cgtcgatgtc ctgcccgcgc aagtgagtga agtgctccac ccactgctgc ccctgcgggc
    32461 cggccaggaa ggagggatgg aagttgagcc ggccgatgac ttcggccaga tcgaccgaga
    32521 tcccccagga agaggcggcc tcgaccatcg ccgtgtacgg ccgcgctgtg cgctcgggct
    32581 ccacataggg ctgggtggac accaggacga ggcgggaaac ggcgtccgga tggcgcagtg
    32641 ctatgcgcag cgccttcata ccgcccatcg agtgccctgc ccagaccacc ggaaactcga
    32701 cgcccaggtc ccccagggct tccacgaggg cgtccgcctc gtcctccagg gagtaggcgc
    32761 cgggccgtgc cgggctgccg ccgtggccgg gcgcgtccac cgtgatcaag cggtagcggt
    32821 cacgcagagc cgcgaccacg ccgtcccagg cccggtggtc ggtcatgagg ccatgaagca
    32881 gcacgatggt gggaccttcg ccctgacagt ggacgcgtag gttccacgaa cccgcggtca
    32941 gggttgccgt cacggccggg ccgccggcgc aacctcgtcc gcgaatgccg tcgttcctgt
    33001 cgcagcaatg ctcaccaggg cattggcggc cctgacatag cgcaacagcg tcggcagatg
    33061 cccggtgacc gcaagctccc cgtcgagcat cgcctccatc gggtcgagct cgccctggat
    33121 gatctgcttc cacagggagt acgggccctg gagtacgaat tgggactcgc ggccctcctg
    33181 cggtgtgacg tcgtacttcc accacaggca tttgccgcct ccaacgccgg ctcgggccca
    33241 gatatcggcc tggtgcccca gctccggttc ggcttcgaag acataggcga tgtcggcctc
    33301 gaaagtacgt gctgcctccg cgaactccgg agacgtgttg atacgggcga cgtattcatc
    33361 gagccagtcg ccactcggga agactgccat cctcactcct tgtcgtgcgg aacccgcagg
    33421 agggcctggc tgggccggcc gcgtgcacgg gactcagcca agcggttcgg tctgactcgc
    33481 agaacacccg tcggacctgc cgtgtggtcc ccgaatcgga cagggccgca ggggtacccc
    33541 gaccgggcca cccatctgtc ctcgaccgcg cactcggcct gcccgatcag gcgctccggc
    33601 ttgccgcgca gaggcggctg ggaatcgggc tccagagctt ccaaggtgtc agggaacaac
    33661 cgcagtccgg catcgctcgc cgggcctaac cgtgaggaag ggtgacgatg gagcatcccc
    33721 gggctgtccg atggtcgata gcagccggcc tgttcgtcga gttcgtaggg ttcctgtacg
    33781 acaccttgtg gcatgaccag cacctgtctg aggtggccat cccgcccagc aagctgatga
    33841 ccgtgcacag cggtatctac ctcggtgagc tactcgtcct gggcatagca ctggccaccc
    33901 ttgcgctgcg tacccgccgg gcccacccac aagccattct gtgggcggtg gtggcgggag
    33961 gcgtcgtcca gatcgccggc agcggccttg acatgtggag ccacgcccac gcctacgaga
    34021 agccgctcta ccacgacacg atctacaccg gcgcagccgt cacgatcatc ggctacctgc
    34081 tgctggaaat ggtggcctcg cgcgcggccc ggcgagagca gctccccgtc ccggaacggc
    34141 ttgccgacca ccgctcggac gaggcgaagc agaccgcgga gcgctgaagg tgctccaccg
    34201 cacggtgacc tgcccggaac ggaacccgca gaggggatcc atgtggcaca gaaccaggat
    34261 gacctcacac ccgatatcgg cgccggctgg gtgctgctcc cgcagagcct gatcgacatg
    34321 ttgcgcgagg agcggttcga gcagggatgg gcctggctgg acggcggtcc gaaaggcatg
    34381 aacgcagcgc agcacgagga cgacgtccct gacacgaccc ccgccgccga ggtactgccg
    34441 agcacttcat gaccgcgttc cggcgcaccg ggacagaccc cgccccacgg ccttccgcga
    34501 gcgccttccg tcctgaccgg ccactaggaa aagacacctg ccatgacgac agccaccacg
    34561 cccccacccc gcagcggccg tgcggcttct gaggtagcgg ttcccgacgt caccagccag
    34621 gtcagcagcc cagccgtagg acagccgctg ctcggtgaac agcgcaaacc ggccaaggag
    34681 gtccagcggc tggaccgggt gatcatccgg ttcgccgggg actcgggtga cggaatgcag
    34741 ctcacgggtg accggttcac ctcggaaacg gcgtcgttcg ggaacgacct ttccacgctg
    34801 ccgaacttcc ccgccgagat ccgggcaccc gcgggaaccc tgccgggcgt gtccagtttc
    34861 cagctccact tcgccgatca cgacatcctc acgcccggcg acgcgcccaa cgtgctcgtc
    34921 gcgatgaacc cggccgcgct gaaggcgaac atcgccgatc tgccgcgcgg cgcggagatc
    34981 atcgtcaaca cggacgagtt caccaagcgg gcgatggcga aggtcggtta cgcggccagc
    35041 ccgctggagg acggctcgct ggaggcgtac gcgatccacc cggtgccgct gacgagcctg
    35101 accgtggagg ccctgaagga ctcggggctg gcgcgcaagg acgcggagcg cgcgaagaac
    35161 atgttcgcgc tgggcctgct gtcgtggatg taccaccggc cgaccgaggg aaccgagaag
    35221 ttcctgcgga agaagttcgc gacgaagccc gacatcgccg aggcgaacgt cgcggcgttc
    35281 cgggccggct ggaacttcgg ggagaccacc gaggacttcg cggtctccta cgagatcgcc
    35341 ccggcctccg ccgccttccc ggccggcacc taccgcaaca tctcggggaa cctggcgctg
    35401 tcgtacggcc tggtcgccgc gagcaagcag gccgacctgc cgctgtacct gggctcgtac
    35461 ccgatcaccc cggcctccga catcctgcac gagctgtcga agcacaagaa cttcggtgtg
    35521 cggacgttcc aggccgagga cgagatcgcg gccatcggcg ccgcgctggg cgccgcgttc
    35581 ggcggggcgc tggccgtcac caccacctcg gggcccggtg tggcgctgaa gtcggagacc
    35641 atcgggctgg cggtgtcgct ggaactgccg ctgctggtgg tggcgatcca gcgcggcggc
    35701 ccgtccaccg ggctgccgac caagaccgag caggccgacc tgctgcaggc gatgtacggg
    35761 cgcaacggcg aggcgccggt gccgatcgtg gccccggcca ccgcggccga ctgcttcgac
    35821 gccgccatcg aggcggcccg gatcgcgctc acctaccgca ccccggtgtt cctgctctcc
    35881 gacggctacc tggccaacgg cagcgagccg tggcggatcc ccgacatcga cgaactgccg
    35941 gacctgcggg tgcagttcgc caccggcccg aaccacacgc tggacaacgg cgacgaggcg
    36001 ttctggccgt acaagcgcga cccgcagacg ctggcccgcc cctgggcggt gcccggcacc
    36061 cccggtctcg aacaccggat cggcggtatc gagaagcagg acggcacggg caacatctcc
    36121 tacgacccgg ccaaccacga cttcatggtc cgcacccgcc aggcgaagat cgacggcatc
    36181 gccgtacccg atgtgaccgt cgatgatccg agtgatgaat ccccggttct gttgatcggc
    36241 tggggctcga cgtacggccc catcgccgct gccatccgcc gactccgtgc ccagggacat
    36301 caggtcgcgc aggtccatct gcgccacctc aacccccttc ccgcaaacct gggcgacatc
    36361 ctcggcggat atcgccatgt cctggtcccg gagatgaacc tcggccagct cgcccacctg
    36421 ctgcgggcga agtacctggt ggacgctcag tcttacaccc aggtgaccgg cctgccgttc
    36481 aagtccgagc agttggctga ccacgtcaag gagaccttcg atgtctgaga tccgctccct
    36541 gtcgttggtc cccaagtccg acaccaagca gtcgatgaag gacttcaaga cggaccagga
    36601 ggtgcgctgg tgccccggct gcggtgatta cgcggtcctg gccgccgtcc agtccttcat
    36661 gcccgagctg ggactcgccc gcgagaacgt cgtcttcgtc tccggcatcg gctgctcgtc
    36721 gcgcttcccg tactacatga acacctacgg gatgcactcc atccacggcc gcgccccggc
    36781 catcgccacc ggactcgcct cctcccggcg ggacttgagc gtctgggtgg tcaccggcga
    36841 cggggacgcg ctgtccatcg ggggcaacca cctcatccac gcgctgcgcc gtaacgtcaa
    36901 cctcaagatc ctgctgttca acaaccggat ctacggcctg acgaagggtc agtactcgcc
    36961 cacctccgag gtcggcaaga tcaccaagtc gaccccgatg ggctcgctgg acgcgccgtt
    37021 caacccggtc tcgctcgcca tcggcgccga ggccagcttc gtggcgcgca ccatcgactc
    37081 cgaccgcaag cacctgcagt cggtgctgcg cgaggccgcc gcccacccgg gcaccgcgct
    37141 ggtggagatc taccagaact gcaacatctt caacgacggc gccttcgacg cgctcaagga
    37201 ccagcagacg gcgcaggacg ccctgatccg gctggagcac gggcagccga tccggttcgg
    37261 cgcgccggcc gaggacggtc tgggctccaa gggcgtcgtc agggacctgg ccaccggcga
    37321 actcaaggtg atcgacgtga ccgtggaagg gacggcaggg gtgctcgtcc acgactccca
    37381 cgccgcgtcg cccaccaccg ccttcgccct gtcccgcctc gccgacccgg acacgctgca
    37441 ccacaccccc atcggggtgc tacgcagcgt cgaacggccg gtctacgacg ccgacatgtc
    37501 cgaccagctg gaacgcgccg tcgaggagaa gggcaagggc gacctcgccg cgctgctcgc
    37561 cggccaggac acctggaccg taaaccctcg ttaggagctg gaactcgaat gacgtacgtg
    37621 atcgcgcaac cgtgtgtcga cgtgaaggac cgggcctgca tcgatgaatg ccccgtcgac
    37681 tgtatttacg agggcccccg caagctctat atccatcccg acgaatgcgt cgactgtggc
    37741 gcgtgcgaac cggtctgccc cgtcgaggcg attttcttcg agacggatgt gccgtccgag
    37801 tgggcgccct acctgaccgc ggaccgggaa gtgttcgccg gcgatcagcc ctccggagcg
    37861 agcgaccatc cgctgacggc cgaccacagt gtggtggatg cggagccggt cagcgaagtt
    37921 cagtgattcc ggggagctgc tgcgccgtgg ggtggtccgg gcctggaggc tcggaccacc
    37981 ccacggttcg tgtcggcccg ggatgccgac cggtcgggag tcagccgatc cggagagagg
    38041 tcgtgcgggt cgcctcgtcg atgtcggagc tgcggaccgt cacggccatc tgccagtcac
    38101 ctggaaaggg cagctggacc gcgggggttg tccaccgtcc agcgccgacg gacgacagga
    38161 ccacgcgcag cgggccgaca tccctgctcg gcagagtgaa ggccatcctc acctcggcca
    38221 cccgtgcggc gcgtccatcg gcgttgatga cctccgctgt caactgagag gcgcccgtat
    38281 cgggagcaga gcgcaacgac accacgactc gtcctgaggc atcgggaccc gcgccacctg
    38341 tgtcgtaggg gacggcggtt ctgatgtcgg cgggccgcac agagccgggt gcggcgacgg
    38401 cctggctgcg accgggcgcg gagttggtga ggagcgtggt gacggccagg acgatgaccg
    38461 ctacggcggt ctcggctgcg acggagcgcc ggagtcgtcg cggatcgtca gggttgatga
    38521 cgggagcagt gtccgcacgc tccaggacac gaaccgtgcc cggaacgacc tgtctggacg
    38581 gtgcggagct acgtgccgac gcgctggcgc gttgcctgac gagatggcgc cgggacagcg
    38641 cccccagggc gaccagcagt acgacagcgc cgaccttgag cagtagcagc cggccgtatc
    38701 cgctgccggt catggccccc catgagccca agccgcgcca cgactgatag atcccggtga
    38761 cgacgagtac cgcgacgcag gactcggcga gcacggagaa ccggtcgacc gatgctgcgg
    38821 tcggcccttt cgggccgggg ctgggcttga gcgtgacgag cagcgcgacc aggccaccga
    38881 tccacaggcc catcgagagc agatgcaggc tgtcggacag cagggccagc ggaacctgaa
    38941 tgccctcagc cgcatgaccg gcggacgccc agttcaccgc gatggcgccc gccagcacca
    39001 ctcccgctgc cgtcagcccg cggcggatgt cccgctgctt gctcgctgcc tcttcccgtc
    39061 gttcgtggag cgggctcaac tcacgtccca gctgactgca cagcagccac aggaaggggc
    39121 cgactgccgc gaggaggacc atccgctggg ccagggcgcc gccgatgggc gtatgaaggg
    39181 tgccggagag caacgacgtg tcgaacatct gggagaacgt tccggcgctt tggtagggcc
    39241 cgctcagcgc cagtgcactc gccgtcgccg tggtgagcgt gatccagccg gccagcagca
    39301 ggcggcgcac gccgcggtgg ttcgcacccg caggccagca gacgagaacg aagccggctg
    39361 ttcccacggt caaggcgtat cccacatacc cgagtgcgcg cgccgttccg tagagcatgc
    39421 tgatggcggg cgccgcgcgt acggcgggca cggacgcggt ggctgaggtg tgcccgaagg
    39481 cgaagacgaa tgccccggag atgatgtgtg agtctgcgga gacggcccgc caggcgacgg
    39541 tgtagctgcc gggttggagg tcctcgcgca gcgcgacgcg cccggcgttc tgctcaccga
    39601 ccaggttctg cggggtaccc gcgtcaacgc gtcggccatc gggagcgata acgcggatcg
    39661 agtcgtcgaa cagtctgacg gactccccga agaccaaggt cacctgccgc ggagcaacct
    39721 ttgccacgga gcctggcacg ggatcggacg tcagcagcgc cgcgtgagcc gaggcgactc
    39781 ctgtcgcggt gaagagccag cacgcagccg tcaccaggag cagcagggcc ttgccgacca
    39841 tctcgttccg atgcgggcgc cgcgcctggg tcatcgtgtg ccccgccgcc ggaccacgct
    39901 cagggccgcc gcaccggttg cggccgcgag gcccagcacg gccaggaccc gtgccagcac
    39961 gtccggagat gacgacgcgg gcgtcactgc cgcagcactg gggctcttgg ccggtgcagc
    40021 ggtcaggcgc agcaccgggg ccggattctc cggctcggct ccggttgtcg acggttggtc
    40081 gatccagcga gccacagtgc cgttgccgta ggtctgcagg accttgaaaa ccagggcatc
    40141 gccggcggtg ggcaaggggc ccatggccag ttcgaactcc tcgaactggt cgatgccgat
    40201 ggctcctccg gtccacacca ccttggacac cgtctcggtg acctgaccgt cgtccgtgga
    40261 cagtggggtt ttgagactgc tcttctccac ctgggaggac caccccggca gcggtcgcgt
    40321 acggaccgag gcaatcggat ggtcagtggg gagcactact tccactcgtg tcgtggtcgt
    40381 gttcttctgc tcactcggta cgtggaagac aactgagacg tagctgccct gaaccgcgtg
    40441 gtccggctgc accgtcacat gcgcggccgc ggccggagca gacagaagga aggcagcggc
    40501 ggcaacagtc gtaacgatca ggggactgcg gtgcacgccg gtaccgaaga gtgaaccggg
    40561 cactcgatgc accgtcctac cggtagatga ccaggtcctg agcggtagct ccgctgagaa
    40621 cgaaggggcg ttcggcgatc ggccgaccgg tgtacaggcg aatgagtgtc tccgcgtcgg
    40681 tcaccaggtc cgccacatac tgctggtcgg gcagccaggt cccgagttcc agatcccggt
    40741 ccggcagatg ggcgatcagc agcggggtgt tgcgttgcgc actgcacctc gccaacagtt
    40801 ccagggcatc gtcggtgccg gccgccgcat aggcgggtgt gagatcccaa gccgcgcgga
    40861 tgtcgcctgc atggacccat tcccccagcc cgatcacatc cagctgcccg gcggagttgc
    40921 tgatgactgg tcccgcggtc ccatagccgt ggtccagctc gtcgatgatc cggctgatgg
    40981 gccagtcctg ccgatcggtg acgtcgcgct ggttgcactc gggggagaag tcgtgcacct
    41041 ggtcgagggt gatgcgggtg agggcggccg agcagtgcgc caaaaggtcc cgtacgttcc
    41101 agccggggca tgcggtcgga tgtgcgaacc accgcaccgg ggccgcgcgg aggacaggaa
    41161 tcaggtcgcg ctgctcggtc agcagaaggc gttcggcaca ggacgagccc gccacggcga
    41221 tgggcatcgt gcggcccccc tgtgcatcgg agggactggc tgtaggcagg acttccatgg
    41281 tcaactccta gaaacagggc tgggctccgg tgcatgcgat tccgccgcgc tgttcgtccc
    41341 tgccagcatc gctcgcagct cactggtggc ggcaggaccg tatgcctggg tgagccgtgc
    41401 ggtgagctcc gggagggtgg cccggtagct ctgcggtccg acggcttcca gagcgcaggc
    41461 cgccatggtg cagcccagca gcgcggccgc gcccgcgtcc aggccgtgcg ctgtcgcagc
    41521 caggaagccg gcgcggaatg cgtcacctgc tccggttgga tccgtgacgt gcggaacggg
    41581 aacggcgggt acgtgcaagg tggtgtgacc gctgcggtcg atgcggacgc caccctcgct
    41641 cagcgtggtg atccaggtgc cgacccgttc caggaccgta ctttccggcc agcctgtgcg
    41701 ctcaaggagc aacgcccgct cgtaggcgtt ggtgaacaag tacctggcgc cgttgaccag
    41761 gcccttgact cggtcggtgt cgagtgttgc caactgctgg gaagggtcgg ccgcgaacgg
    41821 ggtgccagtg gcgcggcagg cgcgggtgtg ccgcagcatc gcttcggggt cgtcgggagc
    41881 gatcagtacg agatccaccg ggcccgctgc ctcaaggacc gaagcgaggt cgatgtctct
    41941 cgcatgacgc atcgctccgg gatagaagga tgcgatctgg ttctgcgcgg cgtcggtggt
    42001 gcacaggaaa cgagcggtgt aggcatccgg aatggttcgg atgtgctgag tgtcgacgcc
    42061 attgccgttc aaccacacgg cgtagtcgga gaagtcgccg cccaccgccg cgacaagcag
    42121 cggattcagc cccagtcgtc ccaggccgag cgcgatgttg gccgcagcgc cgccccggcg
    42181 tatgtggagg ctgtccacca ggaaggacag cgacacgtga gccaattgat cggcgatgag
    42241 ctggtcactg aaccgcccgg ggaacgtcat cagatggtca gtggcgatgg agccggtgac
    42301 agccaggcgc acagcgtgtc ccttctggtg gttcacggac ggattccggc agagacatcg
    42361 gcaggaggcg ctcgttccga aagtggtcag cggccccgcc aggccactga caccggcggg
    42421 gccgcaggca caggggttca gccgacgggc aggaggtacc gctcgtggat gacatccaga
    42481 catcgcacgt cctcgatgtc gatggcgtcc atgtcgatac tgcgaccgct gagctgctcc
    42541 agcagaaaca ggaactccac gaaagtgagg gagtcgatca gccggttctc gatgaggtcg
    42601 aggtcaccag gtatgtcctc acgctcggga tggcgcttga ggatccagtc cttgatctgc
    42661 tgcagcggtg cgtccatggg agttctcctt cgctgagggg gcggtgcgtg ggggagggaa
    42721 tgatccgggg gacgccgccg cgatggcgac cgcataggct ccgtcgtggc tgatgctgat
    42781 ccgtatgccg gatacaccgg cttgttctgc cagccttcgc gcggtggacc gcaggctcag
    42841 gacgggcttg ccgccgggag ccttccgtac ttccatggcg agccagggca gtacgacacc
    42901 gctcgtgttc aaggtcttga aggcggcctc cttggcggcc aaacggccgg ccacggagag
    42961 gatgtccaga ctcccgtcgc gatggcagtc gcccagttcg gccggtgtga gcatgcgcgc
    43021 cagcacctcg tcaccgtgct cggccagcat gcggtccacg cggctggtca gcatgatgtc
    43081 gaccccgata tcgccgggcg ggcactcggc gccgggaccg ttctcatccc tgggcaagtg
    43141 cctgctccac ggcggcagtg gcttccgccc agccgccgaa gcgccgggtc agggccgaga
    43201 gccaccgctc gaggccgaag gccacacaac tggtgaagac cgattcgccg ttcagggtga
    43261 tcgccagtcg ttcgccgaag aagttgcgat gcacgttgac cgaagcgatg gccagatcct
    43321 cgtacaggaa ctcgtacttc accggtgcca gctgctggag ccgggcccgg gagccgccgc
    43381 agtcgtagaa gggatccgtc gccgcctcct tgcgcagggg cagctccagg cgggccgcga
    43441 agttctccac ctgggcggtg aagtgccgta gatgttcctc ggtgaactcc cggtcgccga
    43501 ctgccacgat ctcccgcatg tggaagccca ggagacgtcg caggtcttcg tactgctcct
    43561 cacggcggaa acatcggccc aataccgtga cgcgttgcgg agcgtcgagc tcctggccgg
    43621 cgaggtgcag atacacgccg tagcaagcgg ccgacggaag ggccaagcgg gccgtttcca
    43681 gtgtctgggg ggcgaaaccg ccgtcgaccg gatcatggcc ggcgtccgga ccgttcagac
    43741 gcaacggggc ggtgaccacg gcctggtgcg ggaagttccg gtagtagtca agctccgcca
    43801 gctgctcgac cggtatgagc ggcggcatga tcatgggttg ggctccggcc tggacacccc
    43861 aggactcgaa ggcccggtcg agcaggtaca gcagtgcggt cgcctgcggg ccgaggacgg
    43921 cgacgccggt ggggggcgcg gccgtggtcg accgggtgga caggggagtc atcgtgttcc
    43981 ttccgccggg cgcgccattc aggccgcgta cagctcggag tcggagaaga tgccggtttt
    44041 gacgaagaac gacacgggct tgcggactgc tttgcgttcc gcggtgcgcc ggtacggatc
    44101 ggccaggatg cggctgcgca cctgcagagg atccgagaag cccgcgtccc ggtagacctg
    44161 ggggttgtag aacgactgca ggctgaagac gatgtaccgc ttgaggtagg cctccagctc
    44221 cctcagctgc tcctcgccgg cctgctcgcg gacccgctgg tacaggagcg agacgagttc
    44281 ccgcccaaag gcgatatgcc gtgattcgtc gtgatgatgg atccggttga cctgccggat
    44341 ggtctcgtgc agatcggcgt catcggccat ccgggcgttg tagtggtcga cgatctcctc
    44401 gaagagcaga atgcgggcga agacgaggaa gttctcagtt tcggcactgc ccgcatcctg
    44461 agtcttgatg gaaggggtgg aatagatctt tccagcgccg taacgccgac agaactcggc
    44521 gaagaaccac atgtgctcgt tctcctcacc gatgaagtgg tggaagaact cggagggaac
    44581 ttcgaacccc ggcgtatgga tgcgcctgat gacctcgatc agaagctcac ggattccgtg
    44641 cacgttgagg ctgtagaaat tgatgctctc ccatcgcgac agccgcttca ttccctccac
    44701 gccgatctcg tcctcgaccg gtgtgccatg ggcggtgatc agttcaggag tcatccagta
    44761 ggcgttctcc gggagctggt ccgcccattc gaacatgcga tacgggttgt agtagtcctc
    44821 gacggacatg cggccgagcc ggtcgaggat ttcgacgaag cggtccggca cagcgtggtc
    44881 ggtgatggtc acggatcctc cggagagcga gggggcgggc gggaagcggc acggtacgtc
    44941 ggcgcgacgg ctaggggcgc gcctcgtaga cagcgctgac cggtgtcgcg tctgccttcc
    45001 gccatcgcgt gaatccggca ctgcgggcta tctcgcgcaa ggtgtcctcg cccgagtggt
    45061 tgcccagggc gcgagggccc ttctgggcgg ccgcggccgg cagacacatc actgccgaca
    45121 gagccatgaa cagccgaccc gccgggtgcg tgttgcgcaa cgggtcaggg tcggcgttcg
    45181 gctcaacgat catccacgtg ccgtcggtgg acagctggga gcggatgtgg cgtgccacag
    45241 cgtcgggatc gccgatgtcg tgcacgcagt tgaacgtggt caccaggtcg tacgggccgc
    45301 cctcgaacgc gtccgccccg gcagtcgaga agtccactcg ctcttcgggc aggccgcgtt
    45361 gtgccgccaa gtcccgggcc tgctcgatgg ccagcgcgta gtagtcaaaa ccccgcacct
    45421 gtgcggccgg gaaagcctca gccatgagga acgtggagta ccccaccccg caccccacgt
    45481 ccgcgatccg tccaccatcc ttgagccggt cctctgccgc ctccagcgcg ggtatccacc
    45541 gctgaacaag atgggcgcga tagccaggta ggaagtaccg ggccagggcg tcgtccagcg
    45601 tcccgtcgtg ctcgtcccat cccactccac cgccgtcccg gtacgcgtac accagcgagt
    45661 cctcgctggt gtagagcgcg gccagggcgg agaagaacgg cgccgcgtgg aggtcgctgt
    45721 cgcggtcggc gagggccggc acgtgctcgg ccggcagcca gtaccgcgcg cctgccgcgt
    45781 cggtgcgcag atacccgcca ctgacctggg cgtgcagcca ttcgcgtgcg tacatcggct
    45841 ggatgccggt ccgggaggcc agctcctcgg ctgtgaccgg cttcgaatcg gccatcgcgc
    45901 gatacaggcc gagacggtct ccgagggaga ccgtcaggcc gcgcacggcg gcggccgcat
    45961 cacttacgag gcgttgctga aattcctggg cgggatgggt gttcacagtc ctcgtctcga
    46021 ttccgatggg gaatggaagc ctgcgatgac gcctggccgg cggctcttcg gagacgcccg
    46081 gcggccgaaa agtacggtac ctcggtaggg tattggctcg gccaggtgca gttgaggtag
    46141 cagttccacc cgtccgcccg gctaccccgg aaggggtggc cactcggtca ccacccgccg
    46201 catgcccttg gccccgcgcg cgatgtcctc agctcaccga aggctccgcg gtgaagaaga
    46261 aggagcgggg gacgtcgcgg accttccggg cgatcagcgg gtacggccaa cggccgtagg
    46321 aggcaccggc ttcgcccggt tgaagggtcc gggtggtgtg ccaaccgcag gaacgcagga
    46381 agtcctccgg ctcgtcatgg ccgaactgcc aggcggcgcc gtcctcccgc agagcgctca
    46441 ggaagccgcg cgccatcgga ttggtgagcg atgcgcggct ggccatgtcc cctgccagga
    46501 tgctgccggg tgccgaaagc cgcagcaagg tggcgagcac gctgcgcacg gcctgctccg
    46561 gaaggaagaa cagcagacct tccatgaccc atacggtcgg ctccgcgggc tggaagcccg
    46621 cgtccgtcag tgatccggcc cagtcaccgg cgagatcgac cgctacggca cgccgccggc
    46681 gacccgccgg cagcggggca tcggcgagct gagcgctctt ggcctccagc agggcggggc
    46741 ggtcgagttc gtagatcacc gtgtgctccg gccaagtcaa ccgccacgca cgggtgtcca
    46801 ttcccgcagc gacgaacacc acctgccgtg ccccactgcg cgccaccgct gccaacgcct
    46861 ggtcgtccag gtacttcgtc cgcaacgcca ggaagggcac cgttccggcg ccggtatagc
    46921 gcttgagcag agcgaaaccg gtgtcaccgg ccagcgttcg cgcgaacggg tcgtcgaaca
    46981 gccggtcatc acgttcgctc tccagcgcac gagctgcggc ggtccattgg gctgtacagg
    47041 aaacggcttc cacgatctgt gatcctttcg atggtgacgc ggttcctcag gcccccgccg
    47101 atgctgggcg tcgcaggaag agactgtgca gcgtcatgct gaatacctgc cgccctgcgt
    47161 catcgagcag ttcgcagcga ggctgcacca gcccgcggtc cttgcgaccc agaaccggac
    47221 ccgtgcgcag cacggtcagc cgtgcgctga gggtgtctcc ggggcacacc ggccggtgat
    47281 agcggatctc gtccactcca ggggatcccg cgcaggcgct gtcgcgcagg agaccgtcga
    47341 cgtaggcccg catgaacagc gacgcggtca gccacccact cgcaatcaga cccccgaaag
    47401 ccgaaccctc tgcggcggcc gggtcggtgt ggaagggctg agggtcatac cgtttgccga
    47461 actcgatgat ctcttcggcg gtgacggtca ctgacccgag gtcgtggaca tctccggcgg
    47521 caaagtcttc gaaatagcgc aagatgagcc tcccagggac ggttcgggcg ggtcacagac
    47581 cggacagggc atgtgcgaag tcgccccaca gatcgtcgaa gtgctccagc ccgaccgaga
    47641 cccgtacggt gccttcgccg ataccggccg ccgccaactc cttggcgtcc aattcacgat
    47701 gggaaatgct ggctggatgc agcaccaggg tctccacccc tcccaacgag ggcgccagtc
    47761 gggccaggtg caggcctgcg aggaaggtcc ggccggctgg gcgaccgccg gccagatcga
    47821 aggcgagcac ccctccgaag ccgtccagta cccgcttggc gagaacgtgg tccggatggt
    47881 cgtcgcggcc gggccagtgc accgcggtca ccgtcggatg ctctgcgagg cggtcggcca
    47941 atgacgaggc gttggcgcag tgacgttcca tccgcaggct caatgtctgc aagccgcgga
    48001 tggtcagcca ggcagcgaac gggtcggcgg tggcacccag ttcgacggca tgcttccagc
    48061 acgcttcgta gagcccccgg gaggcgaaga cggcaacgcc acccgtgaca tccgagtggc
    48121 cgcccaggta tttggtgctg gagtggacca cgacgtctgc gccgaattcc agcggccgac
    48181 acagcagtgg agaggcgaag gagttgtcca ccacactgag aaggccggcc tgtcggccga
    48241 ccgccagtac tccgggcagg tcgggaatcc gggtggtggg gttggcgatg gtctccagat
    48301 acagcagccg cgtcgtcggt cggagcagat cccttacctc gtccgcgctc tgccccgaaa
    48361 cataactcac ttcgataccg aaccgctcac tcagatcggt gaacagggag tacgttccgc
    48421 cgtacagaca gcgttgcgcg atcacatggt cgccggtctg cagagccgac agcagcacgg
    48481 cgctgatcgc gcccataccc gaagccgtgg ccagcgcagc ctccccgccc tcgagttcag
    48541 ccactgtctc ttccagcgct cgcacggtgg gattcccgcg ccggctgtag acgaatgcac
    48601 cgtccggacc gttcatcgcc tctgccagat cgtcgggatg atcgaatgcg aatgcggaac
    48661 tctgatagag cggcacgctc agcggctgac aacgtctcag cgggggagcc gagacgtgga
    48721 tggcacgcgt ctgaggatgc tgtaaaccag ttccgagccc ggaagcctgc ttggatgcgt
    48781 cgatgcccac catgggttcc atgctgtaga aagtcgcggg tttccgatag ggagacaaac
    48841 ggtcacctcg ccgcctgatg gaacgtcagg ccattcgagg tgcagcgcag tgaccgatcg
    48901 gtcacaccat cctctgtagc cgaacggcag ggagaacggc catggatcat ccgcaggtac
    48961 tccacgacca tcagatcgaa cgcgccctcg tcatcaccgc acaccccgat gacgtcgact
    49021 tcctcgcctc cggaacggtt gcgaagtgga ctgcgagcgg tatcgaagtc acctactgcg
    49081 tcctcacgga cggcgacgcc ggtggattcg accccgccat ccaacgcgcc gatattccgg
    49141 cgctccgtcg tgaggagcaa cgccgggccg ccgacatcgc cggggtcaag gaagttcact
    49201 tcttgggtta caccgatggc gccctcgaag tcactacgag tctgcgactc gacctcagcc
    49261 gcgtgatccg ccaggtacgc ccgcaacgga tcgtgatgca cagccccgag atcaactggc
    49321 cccacctacc ggatttccac cccgatcacc gcatggcagg cgaagcgaca ctgcgcgcgg
    49381 tctacccgga cgcccgtaac cccttcgccc acc
//
