LOCUS       NZ_CP048835            26510 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7485987
            Orig. end                         :: 7512497
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26510
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="20"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26510
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26510
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16510](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16510
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            844..1401
                     /locus_tag="C8250_RS33545"
                     /old_locus_tag="C8250_033560"
     CDS             844..1401
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175222.1"
                     /locus_tag="C8250_RS33545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033560"
                     /product="ATP-binding protein"
                     /protein_id="WP_232485548.1"
                     /transl_table=11
                     /translation="MVDAVMEVRGSVPPDPATAEVPVDPDDPGGPGASGGPGGPFAPPP
                     PYAGAWRFTAPAVDSSVPQVRHGVRDLITDRKVPVGDDLMAGILLIVSELVTNAVRHAA
                     LLSPQITIEVAVGPDWIRVGVEDNHPYRPKALEAEYGDTGGRGLLLVKAITAEAGGMCD
                     VTHTDSGGKVIWALLPLPFPNS"
     gene            complement(1496..2104)
                     /gene="idi"
                     /locus_tag="C8250_RS33550"
                     /old_locus_tag="C8250_033565"
     CDS             complement(1496..2104)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766530.1"
                     /locus_tag="C8250_RS33550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033565"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_138355758.1"
                     /transl_table=11
                     /translation="MPTSPATGRPGTPATDPSSNGVAEPIMLELVDEAGVTIGTAEKLS
                     AHLAPGRLHRAFSVFLFDDEGRLLLQRRAMGKYHSPGVWSNTCCGHPYPAEPPFVAAAR
                     RTAEELGTAPALLREAGTVRYNHPDPASGLVEQEFNHLFVGLVRAQLRPDPEEIGETAF
                     VTPPELEEIRERGPFSAWFGTVWDASLPAIRELTGDAGW"
     misc_feature    complement(2390..2404)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            2572..4383
                     /locus_tag="C8250_RS33555"
                     /old_locus_tag="C8250_033570"
     CDS             2572..4383
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="C8250_RS33555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033570"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_138355759.1"
                     /transl_table=11
                     /translation="MPTAILTGPPAPASPLEGDLRSLGFDVIEAPESGSESEAAAGGLA
                     ARIAAVPATDRVAIVDRRFVGHTHALRLALTDPRFDASAVPGALAVQAAARPALVRALA
                     AGPAEGLLPDTLATAIEAEGVAPHRPELGVLVAAVPASDADRAEAAAAVAAVDGEKVRL
                     RNAVKARDGFFTTYCISPYSRYLARWCARRGLTPNQVTTASLLVALIAAGCAATGTRPG
                     FVAAGVLLIASFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLALGAARGG
                     DDVWALALGAMVLQTCRHVVDFSFTEANHDATANTSPTAALSDKLDSVGWTVWVRRMIV
                     LPIGERWAMIAVLTAVTTPRITLTVLIIGCALAACYTTAGRVLRSLTRKAVRTDRAAQA
                     LAELADSGPLAEAVARATGPLARRLPSFTAPAIALLGAAALVATAALAPWGSWWPVLAA
                     VVYVLTSGLAVARPLKGALDWLVPPFFRAGEYTTILALAAVSDVNGALPAAFGLVAAVA
                     YHHYDTVYRIRGGTGAPPRALVRATGGHEGRALAVTAAAALAHHTGFTVTLTVIAGALT
                     LVVLTESIRFWVSSAAPAVHDESGEPA"
     gene            4380..5129
                     /locus_tag="C8250_RS33560"
                     /old_locus_tag="C8250_033575"
     CDS             4380..5129
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838712.1"
                     /locus_tag="C8250_RS33560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033575"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_138355760.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.6e-08, bitscore:
                     33.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDPEGAGTTTVLDLTLGN
                     FAEVGLTDAAIVIGYRGEAVVERKAALEKKYGVKLHLVDNDKAETWNNAYSLWCARDIL
                     TEGVILANGDTVHPVSVEKTLLAARGQDRRIILALDTVKKLADEEMKVITDPAKGVQRI
                     TKLMDPATATGEYIGVTLIESSAAADLADALKTTFEKDPDLYYEDGYQELVNRGFTIDT
                     APIGDVAWVEIDNHDDLKKARGIACQY"
     gene            5117..6178
                     /locus_tag="C8250_RS33565"
                     /old_locus_tag="C8250_033580"
     CDS             5117..6178
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="C8250_RS33565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033580"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_138355761.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.3e-20, bitscore: 72.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDINGGALADLAGLLADQRISSSGKLAVAVSG
                     GSGLKLRDRLAPELPGADWYPVDGGTIDAAVKLADAMRGKRYDAVVGLGGGKIIDVAKY
                     AAARVGLPMVAVATNLSHDGICSPVSTLDNDNGRGSYGVPTPIALVIDLDVIREAPVRY
                     VRSGIGDAISNLSAIADWELSHRETGEPIDGLAAAMARSAGESVLRHPGGVGDDAFLTT
                     LAEGLVLSGIAMSISGDTRPSSGACHEISHAFDLLYPKRAAAHGEQVGLGAAFAMYLRG
                     AHEESGLIAEVLRRHGLPVTPGEIGFSDEEFVKAVEYAPQTRPGRYTILEHLDLSADQI
                     KDAYADYAKTISS"
     gene            6156..6935
                     /locus_tag="C8250_RS33570"
                     /old_locus_tag="C8250_033585"
     CDS             6156..6935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="C8250_RS33570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033585"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_138355762.1"
                     /transl_table=11
                     /translation="MPKPSVAELRPVVHPPGVKDRRSGEHWAGRLYMRELSLRIDRHLV
                     NTRVTPNQVTYVMTVAAVLAAPALLVPGIAGAVLGVVMVQLYLLFDCVDGELARWKKQY
                     SLGGVYLDRVAAYLCDAAVLVGFGLRAADLWGSGRIDWLWAFLGTLAALGAVLIKAETD
                     LVGVARHQHGLPPVKEAASEPRSSGMALARKAAAALKFHRLVLGIEASLLILVLAILDQ
                     VRGDLFFSRLGVAVLAGIALLQSLLHLVSILASSRLK"
     gene            6944..7825
                     /locus_tag="C8250_RS33575"
                     /old_locus_tag="C8250_033590"
     CDS             6944..7825
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="C8250_RS33575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033590"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_138355773.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-12, bitscore:
                     46.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPVELRDLLDSVAKQDGPPIEVALVGNGSPLPE
                     LEGSAPRLRTVELPENLGIPGGRNVGVELFGPNGSDVDVVLFLDDDGLLPGTDTGELLR
                     EAFAADPELGIVSFRISDPETGTTQRRHVPRLRASDPMHSSRVTTFLGGASAVRTKVLA
                     QVGGLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPLTEPSRHAVYHRMVARNRV
                     WLARRNLPWPLVPAYLGTWILLTLARRPSGPALRAWIGGFREGWATPCGPRRPMKWRTV
                     WRLTRLGRPPII"
     misc_feature    7895..7913
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.28"
                     /tool="antismash"
     gene            7907..8836
                     /locus_tag="C8250_RS33580"
                     /old_locus_tag="C8250_033595"
     CDS             7907..8836
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="C8250_RS33580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033595"
                     /product="ABC transporter permease"
                     /protein_id="WP_187145071.1"
                     /transl_table=11
                     /translation="MSGTAHDGAVAVSVPSDSPADDGLSASELAAKYGLSVSGARPGLG
                     EYTRQLWGRRHFINEFAKARTQAQYTDARLGQLWQVMTPLLNAAVYYLIFGLLLGTDRG
                     VDNFIAFLVTGIFIFTFTQSSIMSGVKAVSGNLGLIRALHFPRASMPIAFTLMQLQQLL
                     MSMLVLFSIVLMTGEVPTWSWLLAIPALFIQSIFNAGLALAVARLGSKMTDLAQLMPFI
                     LRTWMYTSGVMYSIANFTKDAPYFVKILLDINPVAVYIDLMRFALIDSVTAEQMPPHVW
                     AVAVGWALLAGIGGYVYFWKAEEKYGRG"
     gene            8829..9605
                     /locus_tag="C8250_RS33585"
                     /old_locus_tag="C8250_033600"
     CDS             8829..9605
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145642.1"
                     /locus_tag="C8250_RS33585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033600"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_244809512.1"
                     /transl_table=11
                     /translation="MAEQTETRVPTVIVDDVNIVYRVHGAGNSKGSATAALGRIISRKS
                     SPNVRLVHAVRGVSFTTYRGEAVGLIGSNGSGKSTMLRAIAGLLPPESGRVYTDGQPSL
                     LGVNAALMNDLTGERNVILGGLAMGMSQEEIRERYQGIVEFSGINEKGDFISLPMRTYS
                     SGMAARLRFSIAAAKNHDVLMIDEALATGDRSFQRRSEARIRELRKEAGTVFLVSHNNK
                     SIRDTCDRVLWLEKGELLMDGPTDDVLKAYEEASNK"
     gene            10001..10888
                     /gene="hpnC"
                     /locus_tag="C8250_RS33590"
                     /old_locus_tag="C8250_033605"
     CDS             10001..10888
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951782.1"
                     /locus_tag="C8250_RS33590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033605"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_138358808.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.9e-41, bitscore:
                     138.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3e-38,
                     bitscore: 130.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTADAQSRAVLDKAARENFPVAPFFVPKAWRGDLMAVYGFARLVD
                     DIGDGDLANGGRDDAARLGLPQDAAEDRIVMLDAFEADLRKVFDGTPRHPLLLALQPTV
                     RRHGLTPGPFEGLIEANRQDQRVRRYDTYEDLLAYCELSANPVGRLVLGITGTSTPERN
                     RLSDAVCTALQIVEHLQDVAEDLGRDRIYLPAQDMKRFGVTEADLAAPTAGAQVRALVA
                     FEAERARDLLNEGTPLVGSVRGRLRLLLAGFVGGGRAALKAVESAGYDVLPGPPKATRP
                     SLLREVGSTLRRKG"
     gene            10897..11835
                     /gene="hpnD"
                     /locus_tag="C8250_RS33595"
                     /old_locus_tag="C8250_033610"
     CDS             10897..11835
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552437.1"
                     /locus_tag="C8250_RS33595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033610"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_138358810.1"
                     /sec_met_domain="phytoene_synt (E-value: 3e-54, bitscore:
                     183.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6e-66,
                     bitscore: 221.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGSAHTSGPVLAAYRYCESVTGHEARNFAYGIRLLPLPKRQAMS
                     ALYAFSRRVDDIGDGDLDPAVKQIRLDETRALLARIRAGEIREDDTDPVAVALTDASRR
                     FPLPLGGLDELIDGVLMDVHGETYETWDDLAAYCRCVAGAIGRLSLGVFGTVGPGGRGT
                     GDMERAAGYADTLGLALQLTNILRDVREDASNGRTYLPAQDLAKFGCSEGFHTDTPPPG
                     SDFAGLIEYEVRRARALFATGYQLLPMLDRRSGACVAAMAGIYRRLLDRIAADPEAVLR
                     GRVSLPGHQKAYVAVRGLAGLDARRSARGRG"
     gene            11927..13333
                     /gene="hpnE"
                     /locus_tag="C8250_RS33600"
                     /old_locus_tag="C8250_033615"
     CDS             11927..13333
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100145.1"
                     /locus_tag="C8250_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033615"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_138358812.1"
                     /sec_met_domain="DAO (E-value: 9.3e-07, bitscore: 27.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGSEVSGRPPEAAAVVVGGGLAGTTAALALADAGLRVTLIESRP
                     RLGGLAFSFQRGELTVDNGQHVFLRCCTAYQWFVDRIAARDLVTLQDRLDVPVLDAANM
                     RLGRLRRAALPVPLHLAASLATYPHLSLRERATVGRAALALRALDLADPALDDTDFASW
                     LRDRGQSPRTIEALWDLVGVATLNATAANASLGLAAMVFKTGLLSEAGAADIGWAAAPL
                     GELHDDRARKALDAAGVRIMLRSRVTGIKPAAGGGWLVDAETGPGRGEQLDAGTVVMAL
                     PQRETHGLLPEGALDDPDALLGIGTAPILNVHVVYDRQVLRQPFFAALGSPVQWVFDRT
                     ASSGMTGPGQYLAVSQSAVEDEIDLPVAELRERYLPELERLLPAARGAGVTDFFVTRER
                     TATFAPAPGVGRLRPGAATRAPGLYLAGAWTDTGWPATMESAVRSGLHASREALTALGL
                     PFENDVVRAV"
     gene            13330..14400
                     /locus_tag="C8250_RS33605"
                     /old_locus_tag="C8250_033620"
     CDS             13330..14400
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713873.1"
                     /locus_tag="C8250_RS33605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033620"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_138358814.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.5e-59, bitscore:
                     197.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTASATRGVNVTAAGVLELLERGRTLSTPVLRSAVERLAPPMDT
                     VAAYHFGWIDAAGRPADGDGGKAVRPALALLSAEAAGVPPEVGIPGAVAVELVHNFSLL
                     HDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLEQCTVDAGRATRRLTVA
                     TRKLIDGQAQDISFEHRERVTVEECLEMEGNKTGALLACASSIGAVLGGASDSDADALE
                     EYGYHLGLAFQAIDDLLGIWGDPAATGKQTWSDLRQRKKSLPVVAALAAGGSASEQLGE
                     LLAADAKNPETGAFSEEEFALRAALIEEAGGREWTSQEARRQYATAIAALDKMDMPDEI
                     QRKLVGLADFVVVREK"
     gene            14498..16510
                     /gene="shc"
                     /locus_tag="C8250_RS33610"
                     /old_locus_tag="C8250_033625"
     CDS             14498..16510
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037632.1"
                     /locus_tag="C8250_RS33610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033625"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_138358816.1"
                     /sec_met_domain="T2TS (E-value: 8.4e-151, bitscore: 502.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSPGAPAPQAPSASTTSAPHPVHVGGAEAAAERAARRAA
                     ANLLAAQHPDGWWKGDLETNVTMDSEDLLLRQFLGIQDERTTQAAARWIRSLQRDDGSW
                     PTFHSGPGDLSATVEAYVALRLAGDTPEAPHMANASAWVREAGGVVGARVFTRIWLALF
                     GWWRWEDLPELPPEIIYLPKWFPLNIYAFGCWARQTIVPLTVVAAHRPVRPAPFGISEL
                     HKDPAQPNPPRPPAPLASWDGLFQRLDRALHLYRKVGVRPLRRTALKACARWIIERQED
                     DGCWGGIQPPAVYSVIALHLLGYELDHPVVRAGLDSLDRFAVWPDEDTRMIEACQSPVW
                     DTCLATIALADAGVATDHPALVKAVDWMLDEQITKPGDWAVQRPGLQPGGWAFEFHNDN
                     YPDIDDTAEVVLALLRVQHPDPGRVDAAVEKAVRWNIGMQSKNGAWGAFDADNTSAFPN
                     RLPFCDFGEVIDPPSADVTAHVVEMLASLGLEDDTHTRRGIDWLLAEQEDSGAWFGRWG
                     VNYIYGTGSAVPALVAAGLPVSHPAVRRAVGWLESVQNQDGGWGEDLRSYSDQEWIGRG
                     VSTASQTAWALLALLSAGERDSDAVERGVRWLVDTQKADGSWDEPYFTGTGFPRDFSIN
                     YHLYRMVFPLTALGRYARSEPLGVIGNVTKGKAAG"
     gene            16507..17100
                     /locus_tag="C8250_RS33615"
                     /old_locus_tag="C8250_033630"
     CDS             16507..17100
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139896.1"
                     /locus_tag="C8250_RS33615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033630"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_138358818.1"
                     /transl_table=11
                     /translation="MTALLVVCALGVERFALRGGDRTGAAGPVALLRTGMGPQAADRAV
                     TEALRAPELRDAAVLATGFCAGLSPGMRPGDLVVSDETHGAGQLAAALEAAGHTVHTGR
                     LAGSDHVVRGAERSVLRSTGAIAVDMESTAILHAALARGPRPVAAVRVVVDTPEHELLR
                     VGTLRTGITAFRVLRAILPAFFEWHRTTAVLSWR"
     gene            17106..18131
                     /gene="hpnH"
                     /locus_tag="C8250_RS33620"
                     /old_locus_tag="C8250_033635"
     CDS             17106..18131
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981497.1"
                     /locus_tag="C8250_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033635"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_138358820.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-17, bitscore: 63.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.6e-08, bitscore: 33.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIRVGTYLMEQKLRRRDKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIHEIVRQLVAKRKYVF
                     LCTNALLMRKKMDKFTPSPYFAFTVHIDGLKERHDESVAKEGVFEEAVEAIKEAKKRGF
                     RVTTNSTFFNTDTPQSIIEVLDYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKSFANGNRRKWRLNHSPLFLDFLEGKVDFPCTAWGIPNYSLFGWQRPCYLMSDGYVP
                     TYRELVEETDWDKYGRGKDPRCSNCMAHCGYEPTAVLATMGSLKESLRAARETVAGNRG
                     K"
     misc_feature    complement(17152..17166)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.62"
                     /tool="antismash"
     gene            18149..19306
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="C8250_RS33625"
                     /old_locus_tag="C8250_033640"
     CDS             18149..19306
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957229.1"
                     /locus_tag="C8250_RS33625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033640"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_138358832.1"
                     /transl_table=11
                     /translation="MEPVALGLPAVPSRPLSVRRPSRRIEVGSVPVGGDAPVSVQSMTT
                     TVTADVNATLQQIAELTAAGCQIVRVACPSQDDADALAAIARKSQIPVIADIHFQPKYV
                     FAALDAGCAAVRVNPGNIRQFDDKVKEIAKAAASVGTPIRIGVNAGSLDRRLMEKYGKA
                     TPEALVESALWECSLFEEHGFRDIKISVKHNDPVVMVNAYRLLAGRCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPVEEVKVGIQILESLNLRQRRLEIVSC
                     PSCGRAQVDVYTLANQVSAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVIKTVPESKIVETLIEEAMKIAEQMESDGAFSGVPEVTVG"
     gene            19343..21268
                     /gene="dxs"
                     /locus_tag="C8250_RS33630"
                     /old_locus_tag="C8250_033645"
     CDS             19343..21268
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676210.1"
                     /locus_tag="C8250_RS33630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033645"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_138358822.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 6e-109, bitscore:
                     362.4, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.2e-06, bitscore:
                     25.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILENIRGPRDLKALPESRLDELAADIRHFLVQAVARTGGHLGP
                     NLGVVELTIALHRVFDSPADRVLWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSRAE
                     SEHDVIENSHASTVLGWADGLAKANQVLGKQDHVVAVIGDGALTGGMAWEALNNIAAAK
                     DRPLIIVVNDNERSYGPTIGGLANHLATLRTTDGYERFLAWGKDLLQRTPVVGQPLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPIDGHNIAAVESALRRAARFHGPVLVHCLTQK
                     GRGYAAAEQDEADRFHTVGAMDPLTCEPLAPSNGPSWTSVFGAEMLRIGAERPDVVAIT
                     AAMLQPVGLGAFAAAFPDRIYDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     VLMDVALHKCGVTFVLDRAGVTGVDGASHNGMWDMSILQVVPGLRIAAPRDADQLCAQL
                     REAVEVDDAPTVVRFPKETVGAAVPSLERIGGLDVLRRDLRQDVLLVSVGALAGTCLAV
                     ADLLDERGLGVTVVDPRWVKPVDAALPPLAAGFRMVAVVEDNSRTGGVGSAVAQALRDA
                     DVDVPLRDFGIPQDFLAHAKRGEVLADIGLTPAEIAGRISATLARRNGAGDVGDAIKEL
                     APDDTV"
     misc_feature    19346..19362
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.14"
                     /tool="antismash"
     gene            21255..22679
                     /locus_tag="C8250_RS33635"
                     /old_locus_tag="C8250_033650"
     CDS             21255..22679
                     /NRPS_PKS="Domain: Aminotran_3 (54-376). E-value: 2.7e-90.
                     Score: 294.8. Matches aSDomain:
                     nrpspksdomains_C8250_RS33635_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561019.1"
                     /locus_tag="C8250_RS33635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033650"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_138358824.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.8e-87, bitscore:
                     292.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPSESQPVGPPSVAKGFDLATLLAERGGERYDLHTRHLNHQLPR
                     MLHTIGFDKVYERAEGAHFWDAEGQDYLDMLAGFGVMGLGRHHPVVRKALHDVLDAGLA
                     DLTRFDCQPLPGLLAEKLLTYSPHLDRVFFGNSGTEAVETALKFARYATGRPRILYCSH
                     AFHGLTTGSLSVNGEDGFRDGFAPLLPDTAIPLGDLEALERELKRGDVAALIVEPIQGK
                     GVHETPPGYLRAAQELLHKHKALLIADEVQTGLGRTGDFYAYQHEAGVEPDLLCVSKAL
                     SGGYVPVSATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLATLSVMDDEGVVAN
                     ARHTGDLLRTRLAALVDRYELLREVRGRGLMIGIEFGKPTSLGLRSRWAMLQAARKGLF
                     AQMVVVPLLQRHRILTQVSGDHLEVIKLIPPLIIDESDVDRFVEAFTAVMDDAHGGGGL
                     MWDFGRTLVKQAVANR"
     aSDomain        21417..22382
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS33635_Aminotran_3.1"
                     /evalue="2.70E-90"
                     /label="C8250_RS33635_Aminotran_3.1"
                     /locus_tag="C8250_RS33635"
                     /protein_end="376"
                     /protein_start="54"
                     /score="294.8"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDAEGQDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DAGLADLTRFDCQPLPGLLAEKLLTYSPHLDRVFFGNSGTEAVETALKFARYATGRPRI
                     LYCSHAFHGLTTGSLSVNGEDGFRDGFAPLLPDTAIPLGDLEALERELKRGDVAALIVE
                     PIQGKGVHETPPGYLRAAQELLHKHKALLIADEVQTGLGRTGDFYAYQHEAGVEPDLLC
                     VSKALSGGYVPVSATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLATLSVMDDE
                     GVVANARHTGDLLRTRLAALVDRYELLREVRGRGLMIGIEF"
     gene            22697..23890
                     /locus_tag="C8250_RS33640"
                     /old_locus_tag="C8250_033655"
     CDS             22697..23890
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010350583.1"
                     /locus_tag="C8250_RS33640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033655"
                     /product="serpin family protein"
                     /protein_id="WP_138358826.1"
                     /transl_table=11
                     /translation="MDTATVRAVNALTARWAGVAVTPGKGTAFSAVGVWPLLAFLGGAA
                     DGPARAELEQALGVPAHRAIEHGRALLEALGAADGIDTALGVWTKREVPLREDWVERLP
                     PTVAGRLTGDAAMDRKELDAWAARNTGGLIEEMPVELEASTLMVLASALCVQTRWQQPF
                     TPTTLQPKRGPWAERKVAGLSRSGSDLALLGLAATPAGALTVLDVQGANGIDVRLLLGE
                     ETAGAGDVLRAGTEVLAGAHEVVPGGRLAEGIPGPGIAIQKITSFSSDPQLYTTTAAFT
                     VSDDHDLLQRAELFGLDAARDTSRGHFPGVSEVPLAVAGARQSITASFSAEGFQAAAVT
                     AFAMTAGAAPQKKAKFVAVTFDRPFGFLAVHRATGLVLAAGWVTDPHDAVVDERWSW"
     gene            complement(23906..24748)
                     /locus_tag="C8250_RS33645"
                     /old_locus_tag="C8250_033660"
     CDS             complement(23906..24748)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962500.1"
                     /locus_tag="C8250_RS33645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_033660"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_138358834.1"
                     /transl_table=11
                     /translation="MPQTPATDTEAGTGTATCAEPVLTGVRNFRDVGGLRAADGRRVRP
                     GKLFRSGHLAHTTDEDAAFLATLGLHTIFDFRNADDIRMEGPDVDLPGVQNINMPLSDP
                     AHGADFWHTVRDGDLDALRDALGDGKGAERMTTAYRQLILDRTAQHSRMLELLAEEPAV
                     PALLHCAAGKDRAGTSMAIILLALGVDRADIEADYLESNAAHRRYKVQRGDGATGSAID
                     PEIMKLLSPLFEARLEYLTAAFDTIDEHWGSVDRYLSEGLGCTEERRARLRELLLTDA"
     misc_feature    25134..25143
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    complement(25542..25555)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
ORIGIN
        1 cgcagtttcg gatggcttgc cgcactcggc gccgtcctgg tgctgtgcgg gctgttcggt
       61 ctcgcctaca cggccttcgc caccctcacc tcggtgctgc tcttcggctg gctgctgctg
      121 atcgggggct tcgtcggcct gctgcacgcc gtccagtcac gcgacacgaa cttcttctgg
      181 ctcgcgctgg tcgtcgcggc gctgaacctg gcggcggggg tcgtcgtcat ccgcaggccg
      241 gacggcaccg ccgcggcact gacgatgttc gccgcgctgc tcttcctgac cggcggggtg
      301 ttccggctgt tcggcggcct ggtggtgcgc ggaccgcaga cgctctcgac cgtggtgcag
      361 ggcgcggtcg gcatcctgct gggcgtcctg gtgctggcca actggccgga gagcagccgc
      421 tacgtcctcg gcttcttctt ctccctcatg ctgctcttgg acggcctcgg actgatggcc
      481 ggcggtatcg gcggccggcg ggtcgtcggc atggtcacgg acgcccgcac cgaggcggac
      541 gcccaggcgg aagcccggcg ggaggccgtt gcgggggcgg gcccggaatc cgcggcgtcg
      601 gcgggaccgc cgaatgaccc gatggtggaa cattccacga agcaggaaca aggcgatcgg
      661 aatcggtcgc ccgagtgaca aagtctttcg ctgatggaca tgaagcgccg aaaggtgcgg
      721 acttacgggc acccgcccag tgaactgccc cccactccgg agactcgatc cgtgaggcgg
      781 atctcgccgt cggcccgaca gcgggcagcg gcaagaactg cggggacacg tcacacgaag
      841 gcgatggtgg atgccgtcat ggaggtccgc gggagcgtcc cgcccgatcc ggcgacggcc
      901 gaggtgccgg tcgatccgga tgatccgggt ggtcctggcg cttcgggcgg gccaggcggt
      961 ccgttcgctc cgccgccgcc gtacgccggg gcgtggcgtt tcaccgcacc ggcggtggac
     1021 tcctcggtac cccaggtccg gcacggtgtc cgggatctca tcaccgaccg gaaggtgccc
     1081 gtcggcgacg atctgatggc cggcatcctg ctgatcgtgt cggagctggt gacgaacgcg
     1141 gtccggcacg cggcgctgct gtcgccgcag atcaccatcg aggtcgcggt gggcccggac
     1201 tggatccggg tcggcgtcga ggacaaccac ccctaccgtc ccaaggcgct ggaggcggag
     1261 tacggcgaca ccggcggccg cggcctgctg ctggtcaagg ccatcacggc ggaagccggc
     1321 ggcatgtgcg acgtgacgca caccgactcc ggcggcaagg tgatctgggc gctgctgcca
     1381 ctgccgttcc cgaactcctg agacgtgccc gaacccctga ggctgaaccc ctgaggccgc
     1441 ggagccggtc cgccgggccc gctccgcgga gccgccccgg cggatcagcg cgttcctacc
     1501 agccggcgtc gccggtcagc tcgcggatcg cgggcagcga cgcgtcccac accgttccga
     1561 accaggcgga gaacggcccg cgctcgcgga tctcctccaa ctccggcggc gtcacgaacg
     1621 cggtctcgcc gatctcctcg gggtcgggcc gcagctgcgc ccgtacgagg ccgacgaaca
     1681 ggtggttgaa ctcctgctcg accagcccgg acgccgggtc cgggtggttg tagcggacgg
     1741 tgccggcctc ccgcagcagc gcgggagccg ttcccagctc ctcggcggtg cggcgggcgg
     1801 cggccacgaa cggcggctcg gccgggtacg ggtgcccgca gcaggtgttc gaccagacgc
     1861 cgggggagtg gtacttgccc atcgcccggc gctggagcag cagccggccc tcgtcgtcga
     1921 agaggaagac ggagaaggcg cggtgcagcc ggccgggggc cagatgagcg gacagcttct
     1981 cggcggtgcc gatcgtcaca ccggcctcgt cgaccagctc cagcatgatc ggttccgcga
     2041 ccccgttgct ggagggatcc gtcgcggggg tgccgggccg gccggtggcg ggactggttg
     2101 gcatgtccat ccttcgcatt cgacgacaag tcctcagtct gcctcacgcg ccgctcaccg
     2161 aagtggttgc accgcatgct ccctgtcacc cggacggggt cgctggcaca cgtgtgcctc
     2221 acgttccgga tgccggtgcg acggcatgac gcacagtggc ggggccgcta ccggtgaccc
     2281 ccgtcgtccg cgatgagctg cggcgatgaa gggcgcgaga gccgcgtcgg tgtcacccgg
     2341 acggccgggt acggccaccg cacggccgct gtttgttgct ggcgcccgga tcgaccatga
     2401 tgatcacgtc attcgcacgg cggggagggc cccggcgaag cgcacgagga agcaaacggg
     2461 tggtgaacgg ccgcttccgc ggatccgata gcctctgccg accgccgtcc acaccggccc
     2521 gcccaccgcc gtcctcgccg gcatccccac atgtccaggg agtgagttcc tctgccgacc
     2581 gccatcctca ccggcccgcc ggctccggcg tcgccgctcg agggcgacct gaggtcgctc
     2641 ggattcgacg tgatcgaagc gccggagtcc ggaagcgagt ccgaagcggc ggccggcggt
     2701 ctcgcggcac gtatcgccgc ggtgcccgcc accgaccggg tggcgatcgt cgaccggcgc
     2761 ttcgtcggcc acacgcacgc gctgcggctg gcactcacgg acccccgctt cgacgcctcc
     2821 gccgttcccg gcgcgctggc cgtccaggcc gcggcgcgtc ccgcgctggt cagggcgctc
     2881 gccgccgggc cggccgaggg tctgctgccg gataccctcg ccaccgccat cgaggccgag
     2941 ggggtggctc cgcaccgccc tgagctcggt gtcctggtcg ccgccgtacc cgcctcggac
     3001 gccgaccggg ccgaagccgc agcggccgtc gccgcggtcg acggggagaa ggtccggctg
     3061 cgcaacgccg tcaaggcgcg cgacggcttc ttcaccactt actgcatcag cccgtactcc
     3121 cgctacctcg cgcgctggtg tgcccgccgc gggctgaccc ccaaccaggt caccacagcg
     3181 tccctgctcg tcgcgctcat cgcggccggc tgcgcggcca ccggcacccg gccgggcttc
     3241 gtcgccgccg gtgtcctgct gatcgcctcg ttcgtcctgg actgcaccga cgggcagctg
     3301 gcccgctact cgctgcagta ctcgacgctc ggcgcctggc tcgacgccac cttcgaccgg
     3361 gccaaggagt acgcgtacta cgccggcctc gcgctcggcg cggcccgagg cggtgacgac
     3421 gtgtgggcgc tggcgctcgg cgcgatggtg ctgcagacct gccggcacgt cgtcgacttc
     3481 tcgttcaccg aggccaacca cgacgcgacg gccaacacga gtccgaccgc cgccctgtcc
     3541 gacaagctcg acagcgtcgg ctggacggtc tgggtgcgcc ggatgatcgt gctgccgatc
     3601 ggtgagcgct gggcgatgat cgcggtgctc accgccgtca ccacgccccg catcaccctg
     3661 accgtgctga tcatcggctg cgcgctcgcc gcctgctaca ccaccgccgg ccgggtgctg
     3721 cgctcgctca cccgcaaggc ggtccgcacc gaccgggccg cccaggcgct cgccgagctg
     3781 gccgacagcg gtccgctcgc cgaagccgtc gcccgcgcca ccgggccgct cgcccgccgg
     3841 ctgccgtcct tcaccgcccc cgccatcgcc ctgctcggcg ccgccgcgct ggtggcgacc
     3901 gcggcgctgg ccccatgggg cagctggtgg ccggtgctgg ccgccgtcgt atacgtcctg
     3961 acctcgggtc tggccgtcgc gcggccgctg aagggtgccc tcgactggct ggtcccgccg
     4021 ttcttccggg cgggcgaata caccacgatc ctcgcgctgg cggccgtctc ggacgtgaac
     4081 ggggcattgc ccgccgcttt cggcctggtg gccgccgtcg cctaccatca ctacgacacg
     4141 gtgtaccgca tccgcggcgg caccggggcg ccaccgaggg ccctggtacg cgcgaccggc
     4201 ggacacgagg gcagggcgct ggcggtcacc gcggcggccg ccctcgcgca ccacacaggt
     4261 tttaccgtca cgctgacggt catcgccggg gcgctgacac tcgtggtgct caccgagagc
     4321 atccgtttct gggtgtcgtc agccgcaccc gctgtacacg acgaatcagg agaacccgca
     4381 tgatcggcct cgtgctggca gccggcgccg gacggcgtct gcgtccctac accgacaccc
     4441 tgcccaaggc tctggtgccg gtcgatcccg agggggcggg caccaccacc gtcctggacc
     4501 tgaccctggg caacttcgcc gaggtcggcc tcaccgacgc ggcgatcgtg atcggctacc
     4561 gcggcgaagc cgtcgtcgag cgcaaggccg ccctggagaa gaagtacggc gtcaagctgc
     4621 acctcgtcga caacgacaag gcggagacct ggaacaacgc ctactcgctg tggtgcgccc
     4681 gggacattct cacggagggt gtgatcctcg ccaacggcga caccgtgcac ccggtctccg
     4741 tggagaagac cctgctggcc gcccgcggcc aggaccggcg gatcatcctc gccctcgaca
     4801 cggtgaagaa gctcgccgac gaggagatga aggtcatcac cgacccggcc aagggtgtgc
     4861 agcgcatcac caagctgatg gacccggcca ccgcgaccgg cgagtacatc ggcgtgacgc
     4921 tgatcgagtc gtcggccgcc gccgacctgg ccgacgcgct gaagacgacc ttcgagaagg
     4981 accccgacct ctactacgag gacggctacc aggagctcgt caaccgcggc ttcaccatcg
     5041 acaccgcgcc gatcggcgac gtggcctggg tcgagatcga caaccacgac gacctgaaga
     5101 aggcacgggg gatcgcgtgc cagtactgac ccggctgatc ccctcgccgg tcgtcgtcga
     5161 catcaacggc ggcgctctcg ccgatctggc cggcctcctg gccgaccagc ggatctccag
     5221 ctcgggcaag ctcgccgtcg cggtcagcgg cggctccggc ctcaagctgc gcgaccggct
     5281 ggctcccgag ctgcccggcg ccgactggta cccggtcgac ggcggcacta tcgacgccgc
     5341 cgtcaagctc gccgacgcca tgcgcggcaa gcggtacgac gcggtcgtcg gcctgggcgg
     5401 cggcaagatc atcgacgtcg cgaagtacgc ggccgcccgg gtcgggctgc cgatggtggc
     5461 cgtcgcgacg aacctctcgc acgacggcat ctgttcgccg gtctccacgc tggacaacga
     5521 caacgggcgc ggctcctacg gggtgcccac cccgatagcg ctggtcatcg acctggacgt
     5581 gatccgcgag gccccggtgc gctatgtgcg ctccgggatc ggcgacgcga tctccaacct
     5641 ctccgccatc gcggactggg aactgtcgca ccgtgagacc ggtgagccga tagacggtct
     5701 cgccgccgcc atggcccgct ccgcgggcga gtccgtactg cggcacccgg gcggggtggg
     5761 tgacgacgcg ttcctcacca cgctcgccga gggcctggtg ctctccggca tcgccatgtc
     5821 gatcagcggg gacacccgcc cgtcgtccgg cgcctgccac gagatcagcc acgccttcga
     5881 cctgctgtac ccgaagcgcg ccgccgcgca cggcgagcag gtcggcctgg gcgccgcctt
     5941 cgccatgtac ctgcgcgggg cgcacgagga gtccggcctg atcgccgagg tgctgcgacg
     6001 ccacggcctg ccggtcacgc ccggcgagat cggcttctcc gacgaggagt tcgtcaaggc
     6061 ggtcgagtac gcaccgcaga cccgccccgg gcgctacacg atcctggaac acctcgacct
     6121 gtccgcagac cagatcaagg acgcatacgc cgactatgcc aaaaccatca gtagctgaac
     6181 tccgcccggt cgttcacccc ccaggggtga aggaccggcg gagcggcgag cactgggccg
     6241 gccggctcta catgcgtgag ctctcgctgc gcatcgaccg gcacctggtg aatacgcggg
     6301 tcacccccaa ccaggtgacg tacgtgatga ccgtcgccgc cgtcctcgcc gccccggctc
     6361 tgctggtgcc ggggatcgcc ggtgccgtgc tcggtgtggt gatggtccag ctgtatctgc
     6421 tgttcgactg cgtcgacggc gagctcgccc gctggaagaa gcagtactcg ctgggcgggg
     6481 tgtacctgga ccgcgtcgcc gcctatctgt gcgacgccgc cgtgctggtc ggcttcggtc
     6541 tgcgtgccgc cgatctgtgg ggctccgggc ggatcgactg gctgtgggcg ttcctcggca
     6601 cgctggccgc cctcggtgcc gtgctgatca aggcggagac cgacctggtc ggcgtcgccc
     6661 gtcaccagca cgggctgccg ccggtcaagg aggcggcctc cgagccgcgt tcgtccggta
     6721 tggcgctggc ccgcaaggcc gccgcggcgc tgaagttcca ccggctcgtc ctcggcatcg
     6781 aggcgtcgct gctgatcctg gtgctggcga tcctggacca ggtcaggggc gacctgttct
     6841 tctcgcgcct cggtgtcgcc gtgctggccg gcatcgcgct gctgcagtcc ctcctgcacc
     6901 tggtcagcat cctcgcgtcg agcaggctga agtgagtacg ccgctgaagc tcggcgcggt
     6961 gatcatcacc atgggcaacc gtcccgtgga gttgcgcgac ctgctggact ccgtagccaa
     7021 gcaggacggc ccgccgatcg aggtcgcgct ggtcggcaac ggctccccgc tccccgagct
     7081 ggaagggtcc gcgccgcggc tgcgcaccgt cgagctgccc gagaacctgg gcattcccgg
     7141 cggccgcaac gtcggcgtcg agctcttcgg cccgaacggc tccgatgtcg acgtggtgct
     7201 gttcctggac gacgacgggc tgctgcccgg caccgacacc ggggagctgc tccgcgaggc
     7261 cttcgcggcc gacccggagc tgggcatcgt cagcttccgg atctcggacc cggagaccgg
     7321 caccacccag cgccgccacg tgccgcgcct gcgggcgtcc gacccgatgc actcctcgcg
     7381 ggtgaccacc ttcctgggcg gcgccagcgc ggtccgtacg aaggtgctgg cgcaggtcgg
     7441 cgggctgccg gacgagttct tctacgcgca cgaggagacg gacctggcct ggcgggcgct
     7501 ggacgccggc tggatgatcg actaccggtc ggacatggtc ctgcaccacc cgctcaccga
     7561 gcccagccgg cacgcggtct accaccggat ggtggcccgc aaccgggtgt ggctggcgcg
     7621 ccggaacctg ccctggcccc tggtgcccgc ctatctcggc acctggatcc tgctgacact
     7681 ggccagacgt ccttccggtc ccgccctgcg ggcgtggatc ggtggcttcc gggagggctg
     7741 ggcgacgccc tgcggccccc ggcgccccat gaagtggcgc acggtatggc ggctgacccg
     7801 actgggccga cccccgatca tctgacaagc tcgaacctga gagcatcggt cgcagtccgg
     7861 gaccccccta ccccggacgc gcaccttgag gacgaaagtg tctactgtga gcggaacagc
     7921 gcacgacggc gccgtcgccg tgagtgtccc atcggactcc ccggccgacg acgggctgtc
     7981 ggcttccgag ctggcggcga agtacgggct gtcggtcagc ggtgcccggc cgggcctcgg
     8041 cgagtacacc cggcagttgt ggggccggcg gcacttcatc aacgagttcg cgaaggcgcg
     8101 gacgcaggcg cagtacaccg atgcccggct gggtcagctg tggcaggtga tgacgccgtt
     8161 gctgaacgcg gcggtgtact acctgatctt cgggctgttg ctgggtaccg accgcggtgt
     8221 ggacaacttc atcgcgttcc tggtgacggg catcttcatc ttcacgttca cccagtcgtc
     8281 gatcatgagt ggcgtgaagg cggtctcggg gaacctgggc ctcatccggg ccctgcactt
     8341 cccccgggca tcgatgccga tcgcgttcac gctgatgcag ttgcagcagc tgctgatgtc
     8401 gatgctggtg ctgttctcga tcgtgctgat gaccggcgag gtgccgacct ggtcgtggtt
     8461 gctggcgatt ccggcgctgt tcatccagtc gatcttcaat gccggcctgg cgctggcggt
     8521 ggcccggctg ggcagcaaga tgacggacct cgcgcagctg atgccgttca ttctgcggac
     8581 gtggatgtac acctccggcg tgatgtacag catcgccaac ttcaccaagg acgcaccgta
     8641 cttcgtgaag atcctgctgg acatcaatcc ggtggccgtc tacatcgacc tgatgcgctt
     8701 cgcgctgatc gacagcgtga ccgccgagca gatgccgccg cacgtgtggg cggtcgcggt
     8761 gggctgggct ctcctggcgg gtatcggcgg gtacgtgtat ttctggaagg ctgaggagaa
     8821 gtacggccgt ggctgagcag accgaaaccc gcgtccccac cgtgatcgtc gacgatgtga
     8881 acatcgtcta ccgggtgcac ggcgcgggga acagcaaggg cagcgcgacc gctgccctgg
     8941 gacgcataat ctcgcgcaag tcgtcgccca acgtccggct ggtccatgcc gtacgcgggg
     9001 tgagtttcac tacgtaccgg ggcgaggcgg tcggtctgat cgggtcgaac gggtcgggca
     9061 agtcgacgat gctgcgggcg atcgcgggtc tgctgccgcc ggagagcggc cgggtctaca
     9121 ccgacggcca gccgtcgctg ctgggggtca acgccgcgct gatgaacgat ctgaccggcg
     9181 agcggaacgt gattctcggc ggtctggcga tggggatgtc gcaggaggag atccgcgagc
     9241 ggtaccaggg aatcgtggag ttctcgggaa tcaacgagaa gggcgacttc atctcgttgc
     9301 cgatgcggac gtactcctcg ggcatggcgg cccggctgcg gttctcgatc gcggcggcca
     9361 agaaccatga cgtgctgatg atcgacgagg cgctggccac cggcgaccgc tccttccagc
     9421 gccgctccga ggcccgcatc cgcgaactgc gcaaggaagc gggcacggtc ttcctggtca
     9481 gccacaacaa caagtcgatc cgtgacacct gtgaccgggt gctgtggctg gagaagggcg
     9541 agctcctcat ggacggcccg acggacgacg tgctgaaggc ctacgaagag gccagcaaca
     9601 agtagccggc ggaccggaac agcggtccac gccgccgcac cgacgatcgg gcccccgccg
     9661 ggcagaaccg gcgggggccc gtccggttcc cgcgtgatcc gccgccaggg cccgggcaca
     9721 tcccgtgcgc ccctctccgg ggacgccaac cggcgctgcc gggagcccga ttgccggcgg
     9781 acggggggaa tccgaacgga atcccgcctg tcgctcgcgc ccccggcgta cgccggtgac
     9841 ctgcccgacg taagctgtag cggtgctccg gggtgggcgc ggcgtgtccg aaatgggaag
     9901 attcttccca gcggtgtaga acggggagtg tggcggccat gaagatcggg accatccagc
     9961 tccacagcgc gccggtcgcg catgggacgg gaagcccgcg gtgaccgccg acgcgcagtc
    10021 gcgcgccgtc ctcgacaagg ccgcccgcga gaacttcccc gtcgcaccgt tcttcgtgcc
    10081 gaaggcgtgg cgtggcgatc tgatggccgt ctacggcttc gcccggctcg tcgacgacat
    10141 cggcgacggc gatctggcca acggcggccg ggacgacgcc gcccggctcg gccttccgca
    10201 ggacgcggcc gaggaccgga tcgtcatgct cgacgcgttc gaggccgatc tgcggaaggt
    10261 gttcgacgga accccccgcc atccgctgct cctggcactg cagcccaccg tccgccggca
    10321 cgggctgacc cccggcccct tcgagggtct gatcgaggcc aaccgccagg accagcgggt
    10381 ccggcgctac gacacgtacg aggatctgct cgcctactgc gagctgtccg ccaacccggt
    10441 gggccggctc gttctgggga tcacaggcac ctcgacaccc gagcggaacc ggctctccga
    10501 cgccgtctgc accgcgctgc agatcgtcga gcacttgcag gacgtggccg aggacctcgg
    10561 tcgcgaccgt atctacctgc cggcacagga catgaaacgc ttcggagtca ccgaagcgga
    10621 cctcgccgcc cccaccgctg gcgcacaggt gcgcgcactg gtggcattcg aagcggaacg
    10681 cgcccgggac cttttgaatg aaggcacccc attggtgggt agcgtccgtg gcaggctcag
    10741 gcttctgctc gccggcttcg tcggcggcgg gcgtgccgcg ctgaaggcgg tcgagagcgc
    10801 gggctacgac gtgctcccgg gaccgccgaa agccaccaga ccaagcctgc tgcgcgaagt
    10861 ggggtcgaca ttgcgaagaa aggggtgagg cggaccgtga acggttctgc ccacacgtcc
    10921 gggccggttc tcgccgccta ccgttactgc gagagcgtga ccgggcacga ggcccgcaac
    10981 ttcgcctacg gcatccgcct gctgcccctc cccaagcggc aggccatgtc ggccctctat
    11041 gccttctccc gccgcgtcga cgacatcggc gacggcgacc tcgaccccgc ggtcaagcag
    11101 atccggctcg acgagacccg ggccctgctg gcccggatcc gcgcgggtga gatccgcgag
    11161 gacgacaccg atccggtcgc ggtggcgctc accgacgcgt cacgccggtt tccgctgccg
    11221 ctcggcggac tcgacgagct gatcgacggc gtgctgatgg acgtgcacgg cgagacgtac
    11281 gagacctggg acgacctcgc ggcgtactgc cgctgcgtcg cgggcgccat cggacggctc
    11341 tcgctgggcg tcttcggcac ggtcggcccc ggcggacggg gcaccggcga catggagcgc
    11401 gccgccggat acgccgacac cctcggcctc gccctgcaac tcaccaacat cctgcgggac
    11461 gtccgggagg acgccagcaa cggccggacc tatctgcccg cccaggacct cgccaagttc
    11521 ggctgctcgg aggggttcca caccgacacc ccgccgcccg gctcggactt cgccggcctg
    11581 atcgagtacg aagtacgccg ggcccgcgcc ctgttcgcga ccggctacca attgctacct
    11641 atgctcgacc gccgcagcgg cgcctgtgtg gccgcgatgg cgggtatcta ccgcagactg
    11701 ctggaccgga tcgccgcgga tcccgaggcg gtgctgcgcg gccgggtatc gcttccgggt
    11761 caccagaagg cgtacgtcgc cgtacgcggt ctggccggtc tcgacgcccg ccgctcggca
    11821 cgggggcgcg ggtgacgttc ctagcaacca gtcaggtccc cagcgcgtca gtgccggtga
    11881 cggagcgtcg cgtcgcgtcg ggcgccagcg gaagggggga gtgccgatga ccgggtccga
    11941 ggtttccgga cgtcctccgg aggcggccgc ggtggtcgtg ggcggcgggc tggccggcac
    12001 cacggcggca ctggcgctcg ccgacgccgg gctccgggtg accctgatcg aatcacgtcc
    12061 ccggctgggc ggactggcgt tctcgttcca gcgcggtgag ctgaccgtcg acaacggaca
    12121 gcatgtcttc ctgcgctgct gcaccgccta ccagtggttc gtcgaccgga tcgcggcccg
    12181 cgacctggtc actctccagg accggctcga cgtgcccgtc ctggacgcgg cgaacatgcg
    12241 gctgggccgg ctgcgccgtg ccgcgctgcc cgtaccgctg cacctggcgg cgagcctcgc
    12301 gacgtatccg cacctgtcgc tcagggagcg ggccacggtc ggccgcgccg cgctggcgct
    12361 gcgcgccctg gacctggcgg acccggcgct cgacgacacc gacttcgcca gctggctgcg
    12421 ggaccggggc cagtccccgc gcaccatcga ggcgctgtgg gacctggtgg gcgtcgccac
    12481 gctcaacgcc accgcggcga acgcctcgct ggggctggcc gccatggtct tcaagaccgg
    12541 gctgctgtcc gaggccggcg ccgccgacat cggctgggcg gccgcgccgc tcggcgagct
    12601 gcacgacgac cgggcccgca aggccctgga cgcggcgggc gtacggatca tgctgcggtc
    12661 ccgggtgacc ggcatcaagc cggccgccgg gggcggctgg ctggtcgacg ccgagaccgg
    12721 gccgggtcgc ggcgagcagc tcgacgccgg caccgtcgtc atggccctgc cgcagcgcga
    12781 gacccacggg ctgctgcccg agggcgcgct ggacgacccg gacgcactgc tggggatcgg
    12841 cacggcgccg atcctgaacg tgcacgtcgt ctacgaccgc caggtgctgc gacagccgtt
    12901 cttcgccgcg ctcggcagtc ccgtccagtg ggtcttcgac cggaccgcga gctcgggaat
    12961 gaccggtccc ggccagtacc tggccgtctc gcagtccgcc gtcgaggacg agatcgatct
    13021 gccggtcgcg gaactgcggg agcgctatct gccggagctg gaacgcctgc tgcccgcggc
    13081 caggggcgcc ggtgtgacgg acttcttcgt cacccgggag cgcacggcga ccttcgcccc
    13141 ggctcccggc gtcggccggc tgcggccggg agcggccacc cgcgcccccg gtctgtacct
    13201 ggccggcgcg tggaccgaca ccggctggcc cgcgaccatg gagagcgccg tgcgcagcgg
    13261 actgcacgcc tcccgagaag ctttgaccgc actaggcctt ccgttcgaga acgatgttgt
    13321 gagggccgta tgagcacagc cagtgcaacc agaggagtaa acgtgaccgc tgccggcgtc
    13381 cttgagctgc tggagcgcgg ccgcaccctg tccacaccgg tgctccgctc ggccgtggaa
    13441 cggctcgcgc caccgatgga caccgtcgcc gcctaccact tcgggtggat cgacgcggcc
    13501 ggccggccgg ccgacggcga cggcggcaag gccgtgcgcc ccgcgctggc cctgctgtcc
    13561 gccgaggcgg cgggagtgcc gcccgaggtc ggcatccccg gcgcggtcgc cgtcgagctg
    13621 gtgcacaact tctcactgct gcacgacgac ctgatggacg gcgacgagca gcgccggcac
    13681 cgcgacaccg tatggaaggt gcacggtccc gcccaggcga tcctggtcgg tgacgcgctg
    13741 ttcgcgcttg ccaacgaggt gctgctggaa cagtgcaccg tggacgcggg ccgcgccacc
    13801 cggcggctca ccgtcgcgac ccgcaagctg atcgacggcc aggcccagga catctccttc
    13861 gagcaccgcg agcgggtcac cgtcgaggag tgcctggaga tggagggcaa caagaccggc
    13921 gccctgctgg cctgcgcctc ctccatcggc gcggtgctcg gcggcgcgtc ggactccgac
    13981 gccgacgcgc tggaggagta cggctatcac ctcgggctgg ccttccaggc gatcgacgat
    14041 ctgctcggga tctggggcga cccggccgcg accggcaagc agacctggag cgatctgcgg
    14101 cagcgcaaga agtcactgcc cgtggtcgcc gcgctggcgg cgggcggcag cgcctcggaa
    14161 caactcgggg aactgctcgc ggcagatgcc aagaatcctg aaacaggtgc gttcagtgag
    14221 gaagagttcg ccctgcgggc ggcgttgatc gaagaggcgg gaggccggga gtggacatcc
    14281 caggaagccc gccggcaata cgccactgca atcgccgcgc tggataaaat ggacatgccg
    14341 gacgaaattc aacgtaagct cgtaggcctg gcggattttg tggtggttcg cgagaaataa
    14401 cgatctaacg tggagcgcag cacgtcgccg accaagcacg tgtaacggtc gacggcagcc
    14461 ccaacaccgc agaagtctca actgcaaagg ggaagccatg acagcgacga ccgacggcag
    14521 tccgggggcc ccagcccccc aggcaccttc ggccagcacc acctcggcac cgcaccccgt
    14581 acacgtcggt ggtgccgagg cggcggcgga gcgcgccgcg cggcgcgccg ccgccaacct
    14641 cctggcagcc cagcatcccg acgggtggtg gaagggcgac ctcgagacca acgtgacgat
    14701 ggactccgag gatctgctgc tccgtcagtt cctgggtatc caggacgagc ggaccacgca
    14761 ggccgccgcc cgctggatcc gctcgctgca gcgtgacgac ggttcctggc ccaccttcca
    14821 cagcgggccg ggggacctgt ccgcgacggt cgaggcgtat gtcgcgctgc ggctggcggg
    14881 cgacacgccg gaggcgccgc acatggcgaa cgcctcggcg tgggtgcgcg aggccggtgg
    14941 tgtcgtcggg gcccgggtct tcaccaggat ctggctggcc ctgttcggct ggtggcggtg
    15001 ggaggacctc cccgagctgc cgccggagat catctacctt cccaagtggt tcccgctcaa
    15061 catctacgcc ttcggctgct gggcccggca gaccatcgtc ccgctcaccg tcgtcgccgc
    15121 ccaccggccg gtccggccgg cgcccttcgg gatcagcgaa ctgcacaagg accccgcgca
    15181 gcccaatccg ccgcgcccgc ccgcaccgct cgccagctgg gacggcctgt tccagcggct
    15241 ggaccgggcc ctgcacctgt accgcaaggt cggcgtccgg ccgctgcgcc gtaccgcgct
    15301 caaggcctgc gcgcgctgga tcatcgagcg ccaggaggac gacggctgct ggggcgggat
    15361 ccagccgccc gccgtgtact cggtgatcgc cctgcatctg ctcggctatg aactcgacca
    15421 tccggtcgtg cgggccgggc tcgactcgct ggatcgtttc gccgtgtggc cggacgagga
    15481 cacccgcatg atcgaggcct gtcagtcccc ggtctgggac acctgtctcg ccaccatcgc
    15541 gctggccgac gcgggggtgg cgaccgacca cccggcgctg gtcaaggcgg tcgactggat
    15601 gctcgacgag cagatcacca agccgggcga ctgggcggtc cagcggccgg ggctgcagcc
    15661 gggcggctgg gcgttcgagt tccacaacga caactacccg gacatcgacg acaccgccga
    15721 ggtcgtgctg gccctgctgc gggtccagca ccccgatccg ggacgggtcg acgccgccgt
    15781 ggagaaggcc gtccgctgga acatcggcat gcagtcgaag aacggcgcgt ggggtgcgtt
    15841 cgacgccgac aacaccagcg cgttccccaa ccggctgccg ttctgcgact tcggtgaggt
    15901 catcgacccg ccgtccgccg atgtcaccgc gcacgtggtg gagatgctcg cctcactcgg
    15961 cctggaggac gacacccaca cccggcgcgg catcgactgg ctgctggccg aacaggagga
    16021 cagcggggcc tggttcggcc gctggggcgt caactacatc tacggcaccg gctcggcggt
    16081 gcccgcgctg gtggccgccg gtctcccggt gagccacccc gccgtccggc gggccgtcgg
    16141 ctggctggag agcgtccaga accaggacgg cggctggggc gaggacctgc gctcctactc
    16201 cgaccaggag tggatcggcc gcggtgtctc gaccgcctcg cagaccgcct gggcgctgct
    16261 cgccctgctg tcggcgggcg agcgcgacag cgacgcggtg gagcgcgggg tgcgctggct
    16321 cgtcgacacc cagaaggccg acggatcctg ggacgagccg tacttcaccg ggaccgggtt
    16381 cccccgggac ttctcgatca actaccacct gtaccggatg gtcttcccgc tcacggcgct
    16441 cgggcgctat gcgcggagtg aaccgctcgg agtcatcggc aacgtgacga aggggaaggc
    16501 ggccggatga cggctctgct ggtcgtctgc gctctcggcg tcgaacggtt cgccctgcgg
    16561 ggcggggacc ggaccggcgc cgcggggccc gtcgccctgc tgcgtaccgg catgggaccg
    16621 caggccgccg accgggccgt caccgaagca ctgcgcgccc cggagctgcg ggacgcggcg
    16681 gtgctcgcca ccggattctg cgccgggctc agccccggca tgcgccccgg cgacctggtg
    16741 gtctcggacg agacccacgg ggccggacaa ctggccgccg cgctcgaagc ggcggggcac
    16801 accgttcaca ccggacgcct ggccgggtcc gaccatgtcg tacggggcgc ggaacgctcc
    16861 gttctgcggt cgacaggagc gatcgcggtc gatatggaat ccaccgcaat actccacgcc
    16921 gccctggcgc gcggaccgcg gcctgtcgcc gccgtccgcg ttgttgtcga cactcccgag
    16981 catgaattgc tccgtgtcgg cacgctgcgc accggaatta ccgcattccg cgtgctaagg
    17041 gctattcttc ctgccttttt cgaatggcac cgtactaccg ctgtgctctc ctggaggtga
    17101 gctagatggc tatgccgctc cgccagtcca tccgggtcgg aacgtacctc atggaacaga
    17161 agctccgacg ccgtgacaag ttccccttga tcgtggaact ggagccgctg ttcgcctgca
    17221 acctggcctg cgagggctgt ggaaagatcc agcacccggc gggagttctc aagcagcgca
    17281 tgccggtcgc ccaggcggtc ggcgcggtgc tcgaatccgg tgccccgatg gtgtccatcg
    17341 ccggtggtga gcccttgatg caccctcaga tccacgagat cgtgcgtcag ttggtggcca
    17401 agcggaagta cgtcttcctc tgcaccaacg cgctgctgat gcgcaagaag atggacaagt
    17461 tcacgccgtc cccgtacttc gccttcacgg tccacatcga cgggctgaag gagcggcacg
    17521 acgagtcggt cgccaaggag ggtgtcttcg aggaagcggt cgaggcgatc aaggaggcca
    17581 agaagcgcgg cttccgggtc accaccaact cgaccttctt caacaccgac accccgcaga
    17641 gcatcatcga ggtcctcgac tacctcaatg acgatctgaa ggtcgacgag atgatgatct
    17701 cgcccgccta cgcctacgag aaggcgcccg accaggagca cttcctcggc gtcgagcaga
    17761 ccagggagct gttcaagaag tccttcgcga acggcaaccg caggaagtgg cggctcaacc
    17821 acagcccgct tttcctggac ttcctggaag gcaaggtgga cttcccgtgc accgcctggg
    17881 gcatccccaa ctactcgctc ttcggctggc agcgcccctg ctacctgatg agcgacgggt
    17941 atgtgccgac gtaccgggag ctcgtcgagg agaccgactg ggacaagtac ggccgcggca
    18001 aggacccgcg ctgctccaac tgcatggcgc actgcggcta cgagccgacc gccgtactcg
    18061 ccacgatggg ctccctcaag gagtcgctcc gcgccgcccg tgagacggtg gccggaaacc
    18121 gcgggaagtg acgagcgcga tgtcgggaat cgagccggta gcgctcggcc tgcccgccgt
    18181 accgtcccgc ccgctctcgg tgcgccgccc ctcgcggcgc atcgaggtcg ggtcggtccc
    18241 ggtgggcggg gacgccccgg tgtcggtcca gtcgatgacg acgacggtga ccgcggacgt
    18301 gaacgcgacg ctgcagcaga tcgcggagct gacggccgcc ggctgccaga tcgtccgggt
    18361 ggcctgccct tcgcaggacg acgcggacgc gctggcggcg atcgcgagga agtcgcagat
    18421 cccggtgatc gcggacattc acttccagcc gaagtacgtc ttcgcggcgc tcgacgccgg
    18481 ctgtgcggcg gtgcgggtga atcccgggaa catccggcag ttcgacgaca aggtcaagga
    18541 gatcgcgaag gcggcggctt cggtcggcac cccgatccgg atcggtgtca acgcgggttc
    18601 gctggaccgc cggctgatgg agaagtacgg caaggcgact cctgaggcgc tggtggagtc
    18661 ggcgctgtgg gagtgctcgc tgttcgagga gcacggtttc cgtgacatca agatctcggt
    18721 gaagcacaac gacccggtcg tgatggtcaa cgcctaccgg ctgctcgccg gcaggtgcga
    18781 ctacccgctg cacctgggtg tgaccgaggc cggtcccgcg ttccagggca ccatcaagtc
    18841 cgccgtcgcg ttcggcgcgc tgctgtccga gggcatcggc gacaccatcc gcgtctcgct
    18901 ctccgccccg ccggtcgagg aggtgaaggt cggcatccag atcctggagt cgctgaatct
    18961 gcggcagcgg cggctggaga tcgtgtcctg tccgtcgtgc gggcgggcgc aggtcgacgt
    19021 ctacacgctc gcgaaccagg tctcggccgg tctggagggg atggaggtgc cgttgcgcgt
    19081 cgccgtcatg gggtgcgtcg tcaacggtcc gggggaggcc cgggaagcgg atctcggtgt
    19141 cgcgtccggc aacggcaagg gccagatctt cgtcaagggc gaggtcatca agaccgtgcc
    19201 ggagtcgaag atcgtggaga ccctgatcga agaggcgatg aagatcgccg agcagatgga
    19261 atccgacggc gcgttctccg gggtaccgga agtcactgtc ggctgaccgc agcaatcccg
    19321 gtagggggga acgaggtcca tcgtgtcgat actggagaac atccggggcc cgcgcgacct
    19381 gaaggcactg cccgaatccc gactcgacga actcgccgcc gatatccgcc acttcctcgt
    19441 gcaggcggtg gcgagaaccg gcggccatct cggacccaac ctgggcgtgg tcgagctgac
    19501 catcgccctg caccgggtct tcgactcgcc cgccgaccgt gtcctgtggg acaccggtca
    19561 ccagtcctac gtccacaagc tgctcaccgg gcggcaggac ttctcgaagc tgcgcggcaa
    19621 gggcggcctg tccggctatc cgtcgcgcgc cgagtccgag cacgacgtca tcgagaacag
    19681 ccatgcctcg acggtgctgg ggtgggccga cggcctcgcc aaggccaacc aggtgctcgg
    19741 caaacaggac cacgtggtcg cggtcatcgg tgacggcgcg ctgaccggcg gtatggcctg
    19801 ggaggcgctg aacaacatcg ccgcggccaa ggaccggccg ctgatcatcg tcgtcaacga
    19861 caacgagcgc tcctacgggc cgacgatcgg cggcctcgcc aaccacctgg cgacgctgcg
    19921 caccaccgac ggctacgagc gcttcctcgc ctggggcaag gacctcctgc agcggacccc
    19981 ggtcgtgggc cagccgctgt acgagtccct gcacggcgcg aagaagggct tcaaggacgc
    20041 cttcgccccg cagggcatgt tcgaggacct ggggctgaag tacgtcggac cgatcgacgg
    20101 ccacaacatc gcggccgtcg agtccgcgct gcgccgcgcc gcgcgcttcc acggaccggt
    20161 gctcgtgcac tgcctgaccc agaagggccg cggttacgcg gcggcggagc aggacgaggc
    20221 cgaccgcttc cacaccgtcg gcgccatgga cccgctcacc tgcgagccgc tcgcgccgtc
    20281 caacggcccc tcgtggacgt cggtcttcgg cgccgagatg ctgcggatcg gcgcggagcg
    20341 cccggacgtc gtcgccatca ccgccgccat gctgcaaccc gtcgggctag gcgccttcgc
    20401 cgccgcgttc ccggaccgga tctacgacgt cggtatcgcc gagcagcatg ccgccgtctc
    20461 ggcggcgggc ctggccaccg gcgggctgca cccggtggtc gcggtgtacg cgacgttcct
    20521 gaaccgcgcg ttcgaccagg tgctgatgga tgtggcgctg cacaagtgcg gtgtgacgtt
    20581 cgtgctggac cgggcgggcg tcaccggtgt ggacggcgct tcgcacaacg gcatgtggga
    20641 catgtcgatc ctccaggtcg tgcccgggct gcggatcgcc gccccgcgcg acgccgacca
    20701 gctgtgcgcc cagctgcgcg aggccgtcga ggtcgacgac gcgcccaccg tcgtccggtt
    20761 ccccaaggag acggtcggtg cggcggtgcc gtccctggag cggatcggcg ggctcgacgt
    20821 cctgcgccgc gaccttcgcc aggacgtgct gctggtatcg gtcggcgccc tcgccggcac
    20881 ctgcctggcg gtcgcggacc tgctggacga acgcggcctc ggcgtcacgg tcgtcgaccc
    20941 ccgctgggtc aaaccggtcg acgccgcgct gccaccgctc gccgccgggt tccgcatggt
    21001 ggcggtcgtc gaggacaaca gccgtaccgg cggcgtcggt tcggccgtcg cgcaggcact
    21061 gcgggacgcg gacgtcgacg taccgctgcg cgacttcggc atcccgcagg acttcctggc
    21121 ccatgccaaa cgcggcgaag tgctcgccga catcggactc accccggccg agatcgccgg
    21181 ccggatcagt gccacactcg cccgccgcaa cggggccggc gacgtgggcg acgcaatcaa
    21241 ggagctggca cccgatgaca ccgtctgagt cgcagcccgt cggaccacca tccgtggcca
    21301 agggcttcga cctcgcgacc ctcctcgccg aacgcggcgg cgagcgctac gacctgcaca
    21361 cccggcacct caaccaccaa ctgccgcgca tgctgcacac catcggcttc gacaaggtct
    21421 acgagcgggc cgagggcgcg cacttctggg acgccgaggg ccaggactat ctcgacatgc
    21481 tcgccggctt cggggtgatg ggcctgggcc ggcaccaccc cgtcgtccgc aaggcgctgc
    21541 acgacgtcct ggacgcgggt ctcgccgacc tgacccgctt cgactgccag ccgctgcccg
    21601 gactgctcgc cgagaagctg ctcacctaca gcccgcacct ggaccgggtg ttcttcggca
    21661 acagcggcac cgaggccgtc gagaccgcgc tgaagttcgc ccgctacgcc accggcaggc
    21721 cgcggatcct gtactgctcg cacgccttcc acgggctgac gacggggtcg ctgtccgtca
    21781 acggcgagga cggcttccgc gacggcttcg ccccgctgct gcccgacacc gcgatcccgc
    21841 tcggcgatct ggaggcgctg gaacgggagt tgaagcgcgg tgacgtggcc gcactgatcg
    21901 tggagcccat ccagggcaag ggcgtccatg agaccccgcc cggctacctc cgcgccgcgc
    21961 aggaactgct gcacaagcac aaggcgctgc tgatcgccga cgaggtgcag accggcctcg
    22021 gacggaccgg cgacttctac gcctaccagc acgaggccgg ggtcgagccc gatctgttgt
    22081 gcgtttccaa ggcgctgtcg ggcggctatg tgccggtcag cgccacgctc ggcaaggact
    22141 ggatcttcaa gaaggtctac tcctcgatgg accgggtcct ggtgcactcc gccagcttcg
    22201 gttccaacgc ccaggcgatg gcggcggggt tggccaccct gtccgtcatg gacgacgagg
    22261 gcgtcgtcgc caacgcccgg cacaccggcg acctgttgcg cacccggctg gccgccctcg
    22321 tcgaccgcta cgagctgctg cgcgaggtgc gcgggcgcgg gctgatgatc ggtatcgagt
    22381 tcggcaagcc gacctccctg ggcctgcgca gccgctgggc gatgctccag gccgcccgca
    22441 agggcctgtt cgcgcagatg gtggtggtgc cgctgctgca gcggcaccgg atcctcactc
    22501 aggtctcggg cgatcacctc gaagtcatta agctgatccc tccgctgatc atcgacgagt
    22561 cggacgtgga ccgcttcgtc gaggcgttca ccgccgtgat ggacgacgcg cacggtggcg
    22621 gcgggctgat gtgggacttc gggcggacgc tggtcaagca ggcggtcgcc aatcggtgag
    22681 aacggggtgg cgagtgatgg acacggcgac ggtgcgggcg gtcaacgcgt tgacggcgcg
    22741 gtgggcgggg gtggcggtca cgccgggaaa gggcaccgcg ttcagcgcgg tcggcgtctg
    22801 gccgttgctg gccttcctcg gcggtgcggc ggacggcccg gcccgcgctg agctcgagca
    22861 ggcgctcggt gtgcccgcgc accgcgccat cgagcacggc cgcgcgctgc tggaggcgct
    22921 gggcgcggcc gacggcatcg acacggcact gggcgtctgg acgaagcggg aggtgccgct
    22981 gcgcgaggac tgggtggagc gccttccgcc caccgtcgcc ggccggctga ccggcgacgc
    23041 ggccatggac cgcaaggaac tcgacgcctg ggccgcacgc aacaccggcg gtttgatcga
    23101 ggagatgccc gtcgaactgg aagcctccac gctgatggtg ctcgcgagcg cgctgtgcgt
    23161 gcagaccagg tggcagcagc cgttcacgcc gaccactctg cagccaaagc gcggcccctg
    23221 ggcggagcgc aaggtcgcgg ggctgtccag gtccggctcc gacctggctt tgctgggcct
    23281 cgcggcgacc ccggccggag cgctcaccgt cctggacgtc cagggtgcga acggcatcga
    23341 cgtccggctg ctgctcggcg aggagactgc cggggccggt gacgtgctcc gggcgggtac
    23401 tgaggtgctg gccggggcgc acgaggtggt acccggcggg cggctggccg agggcatccc
    23461 gggtcccggg atcgcgatcc agaagatcac cagcttcagc tccgacccgc agctgtacac
    23521 gacgaccgcg gccttcaccg tcagcgacga ccacgacctg ctgcagcgag cggagttgtt
    23581 cggcctcgac gcggcccgcg acacgagccg cggtcacttc ccgggggtca gcgaggtgcc
    23641 gctggcggtg gccggcgccc ggcagtcgat cacggcctcg ttcagcgcgg agggattcca
    23701 ggccgcggcc gtgaccgcct tcgccatgac cgcgggcgcg gcaccgcaga agaaggcgaa
    23761 gttcgtggcc gtgaccttcg accgcccctt cggcttcctc gccgtgcacc gcgccaccgg
    23821 gctggtgctg gccgcgggct gggtcaccga cccgcacgac gcggtcgtcg acgagcggtg
    23881 gagctggtga cccggcgggc gtgtctcagg cgtccgtgag gagcagctcg cgcagtcgcg
    23941 cgcgccgctc ctccgtacag cccaggccct cggagagata gcggtcgacg gagccccagt
    24001 gctcgtcgat ggtgtcgaag gcggcggtca ggtattccag ccgggcctcg aagagcgggc
    24061 tgaggagctt catgatctcc gggtcgatgg cggagccggt ggcgccgtca ccgcgctgga
    24121 ccttgtagcg gcggtgggcc gcgttgctct ccaggtagtc ggcctcgata tcggcgcggt
    24181 ccacgccgag ggcgagcagg atgatcgcca tcgacgtacc ggcccggtcc ttgcccgcgg
    24241 cgcagtgcag cagggccggg acggcgggct cctcggcgag cagttccagc atgcggctgt
    24301 gctgggcggt gcggtccagg atgagctgcc ggtaggcggt ggtcatccgc tcggcgccct
    24361 tgccgtcgcc gagggcgtcg cgcagcgcgt ccaggtcgcc gtcgcgcacg gtgtgccaga
    24421 agtcggctcc gtgagccggg tcgctgagcg gcatgttgat gttctggacg cctggcagat
    24481 cgacgtcggg gccttccatc ctgatgtcgt cggcgttgcg gaagtcgaag atcgtgtgca
    24541 gaccgagggt ggccaggaag gccgcgtcct cgtcggtggt gtgcgcgagg tgaccgctgc
    24601 ggaacagctt ccccggccgg acccggcgac cgtcggcggc gcggagaccg cccacgtcac
    24661 ggaagtttcg gacaccggtc agtaccggct cggcacaggt cgcggtgccg gtccctgctt
    24721 cggtgtcggt ggcgggggtc tgcggcagct gctgggtcac cggcgctcct tcgggtcacg
    24781 gctcagagct cggggctgaa cctcagccga cgatacgaca ccggctccac cgacgtaccg
    24841 gccggtatgt gtccgccgcg ccattgcctt cgggttccgc ccgcgtaacg atgttcggac
    24901 gtgatcggaa aaggggagtt ctgatgatcg agacgggcgg aaccgggcgg ctgtggctgc
    24961 tctcgggtcc cggcagcagc tacgccgtgc atctgaccga gcgcgacgag ctgcttcatc
    25021 tgcactgggg cgcccgcatc cagctcgccg acgccgaggc gctggccgcg gaaccgctcc
    25081 ctgacgggag ctccttcgag tcggcgctcg acggccacga ggagtacccc gtcgaaggcg
    25141 gcccgcgctt cgtccggccc gcgctctcgg tccgtgacgc cacggcgcgc ggtaccgaat
    25201 ggtgcttcga ggaggccgag accgaggacg acgagctgcg gctgcacttc cacgactccg
    25261 tccaccatct cgacctgacg ctgcactacc gggtccgcgc gggatccgac gtcgtcgagc
    25321 gctggaccac cgccacccat gtggccaacg gacacaccgg cgccgtcgag ttgctgcgcg
    25381 ccgattccgc cgcctggacc ctgccggaac gcgacggctg gcggctgtcg cacctgcacg
    25441 gccgctgggc ggccgagacc cggctggcga ggaccgcact caccgccggt gagaaggtga
    25501 tcggcagccg gcgcggccac accggccacc accacctgcc gtggatcggc ctcgacgcgg
    25561 gcgacgcggg cgaggagcag ggcgaggtgt ggaccgccgc gctggcctgg tccggctcct
    25621 ggcgcatcgc cgtgcagcag ctgcccgacg gccgggtgca ggccaccggt ggcgccgggc
    25681 acgacgacgc gggactggtg ctgctcgagc cgggggagtc cttcaccacc ccggtcttcg
    25741 ccgggctcca cacggacggc ggcttcggcg ccgccagccg cgcctggcac gcctaccagc
    25801 tggcccatgt gatcccggac gccgggcagc cgcggccggt gctctacaac tcgtgggagg
    25861 cgacccgctt cgacgtcggc gaggagcagc agcgcgaact cgcccgccgg gccgcggcga
    25921 tgggcgtcga gctcttcgtc gtcgacgacg gctggttcgg tgccaggacc agcgaccgcg
    25981 ccggactggg cgactggacc gccaaccccg accggttccc gaacgggctc aagccgctcg
    26041 ccgacgatgt gcacgccctc ggcatgcggt tcggcatctg ggtggaaccg gagatggtca
    26101 accccgacag cgacctgtac cgagcgcatc cggactgggt gcagcaccac accggacgac
    26161 ggcgcaccga gttccgcaac cagctgatcc tcaacctcgc ccgcgaggac gtgcgcgagt
    26221 acctgtggga gcagttggac gcgctgctgc acagcgcccc cgtcgactac gtgaagtggg
    26281 acttcaaccg gtgcttcacc gacgccggct ggcccggtga gccgtacccg cagcggctgt
    26341 gggtcgacca tgtgcagggg ctgtacgggc tgctcgaccg gctgcgggcc gcacaccccg
    26401 gcgtcgcctt cgaatcctgc tcgggcggcg gcggccgggt ggacctcggg atcctgtccc
    26461 gtaccgacca ggtgtggacc tcggacaaca ccgacccgct ggaccggctg
//
