LOCUS       NZ_CP048835            11327 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7141986
            Orig. end                         :: 7153313
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..11327
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="18"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11327
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11327
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6327](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6327)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            730..1464
                     /gene="hemQ"
                     /locus_tag="C8250_RS31930"
                     /old_locus_tag="C8250_031940"
     CDS             730..1464
                     /EC_number="1.3.98.5"
                     /codon_start=1
                     /gene="hemQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981978.1"
                     /locus_tag="C8250_RS31930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031940"
                     /product="hydrogen peroxide-dependent heme synthase"
                     /protein_id="WP_138354291.1"
                     /transl_table=11
                     /translation="MTDSTAAPDAPDRTPNAGKKAKDLNEIIRYTLWSVFRLRDVLPED
                     RSGYADEVEELFAQLAAKDVTVRGTYDVSGLRADADLMIWWHAETAEALQEAYNLFRRT
                     RLGRAMVPVWSNMALHRPAEFNKSHVPAFIADETVRKYVSVYPFVRSYDWYLLPDEDRR
                     RMLADHGKMARGFPDVRANTVPAFTLGDYEWILAFEADELHRIVDLMRHLRASEARMHV
                     REEVPFYTGRRKEIGELVAGLA"
     gene            complement(1473..3044)
                     /locus_tag="C8250_RS31935"
                     /old_locus_tag="C8250_031945"
     CDS             complement(1473..3044)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (106-472). E-value:
                     1.1e-21. Score: 69.6. Matches aSDomain:
                     nrpspksdomains_C8250_RS31935_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824197.1"
                     /locus_tag="C8250_RS31935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031945"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_138354292.1"
                     /sec_met_domain="PF00561 (E-value: 1.6e-26, bitscore: 92.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSIALYGVAGTLALSTLAIAPPGSAAPGPPHGDRVAEARGAAVA
                     AERAALAGVTFGRCAGATRLPASVRCGTVSVPLDYARPDGERINLVISRVAATGPAGER
                     QGALVYNPGGPGGSGLYFPLFSVLKVKEYAKAARAYDFVGFDPRGVGRSAPISCEAPAD
                     YVKAPTRDPRPTSERDKQARIEDAKAYAEGCERRSGHLLPYLTSLNSARDLDVIRAALG
                     ERKLNFYGASYGTYLGAVYATLFPRHVRRMVFDSVVDPDPRQIWYQANLEQDAAFEIRW
                     ADWRDWVAKYDSAYHLGTDRTQVQEAYDAVRAELAVRPAGGVVGPGQLQAAYLGAGYYD
                     DTWPELAAALSAYVHGDPKPLITEASPNPARAVENENGNAVYTAVECADSPWPRDWFTW
                     DRDNTALARTAPFETWDNAWMNLPCAFWKGPHRQPLEVRTFGHELPPVLLVSAERDAAT
                     PHAGAVELQRRLPRSVLLTERRSGSHGVAYGSNTCVNNRVDAYLLRGETGTDRTPTCGP
                     HPEPKP"
     aSDomain        complement(1629..2726)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS31935_Abhydrolase_1.1"
                     /evalue="1.10E-21"
                     /label="C8250_RS31935_Abhydrolase_1.1"
                     /locus_tag="C8250_RS31935"
                     /protein_end="472"
                     /protein_start="106"
                     /score="69.6"
                     /tool="antismash"
                     /translation="ALVYNPGGPGGSGLYFPLFSVLKVKEYAKAARAYDFVGFDPRGVG
                     RSAPISCEAPADYVKAPTRDPRPTSERDKQARIEDAKAYAEGCERRSGHLLPYLTSLNS
                     ARDLDVIRAALGERKLNFYGASYGTYLGAVYATLFPRHVRRMVFDSVVDPDPRQIWYQA
                     NLEQDAAFEIRWADWRDWVAKYDSAYHLGTDRTQVQEAYDAVRAELAVRPAGGVVGPGQ
                     LQAAYLGAGYYDDTWPELAAALSAYVHGDPKPLITEASPNPARAVENENGNAVYTAVEC
                     ADSPWPRDWFTWDRDNTALARTAPFETWDNAWMNLPCAFWKGPHRQPLEVRTFGHELPP
                     VLLVSAERDAATPHAGAVELQRRLPR"
     gene            complement(3153..3893)
                     /locus_tag="C8250_RS31940"
                     /old_locus_tag="C8250_031950"
     CDS             complement(3153..3893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535540.1"
                     /locus_tag="C8250_RS31940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031950"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_138354293.1"
                     /transl_table=11
                     /translation="MWMLFLLVACVAAVVSCARLCRAAIAAGALPAAGPGGRPQVAGLG
                     LYETAFLSGGPRRVTDLTLVSMAGEQRLLLAHTGWATVVDAEGRDDLERSLIASIGPDG
                     QSPVAAIRVAHAAAGAIRALGERLVGDGLAVPAAARESVTAGIRQVRGAILLNLLMAGA
                     ALVLSAGGQPDGGQAQAWFALPLLLTTGCWIIARVEVHPYTRWASPAGQDALRAVPDGP
                     GPLSALAVRGPAALLDPAQRAALG"
     gene            complement(3967..4995)
                     /locus_tag="C8250_RS31945"
                     /old_locus_tag="C8250_031955"
     CDS             complement(3967..4995)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="C8250_RS31945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031955"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_138354294.1"
                     /transl_table=11
                     /translation="MNVMTGLMLTVYLLIAATSAYLVGEKIRARRFTRPYHGDIPRDPL
                     ETAFLAGGPGRVADTVIAAMHADGRIAVDASGQLTVLRPVASNPVETALLEACGAEWGG
                     GLRQVRTAVLTGSPVQSIGDRLARRGLFFQPEVHRRWRRVSTLHKTVWCLLLFLSLAEV
                     MPHLVVGSGLPLFVRVLPGLAVGLFVLLTCSAPRGRLTPAGKRVLHGLRLSNRPLLASR
                     TASTGSDATMLFALAGAASIQDTVLRDQLAQSSQPSSDASDPGSWGDAAGGWAGGGTSC
                     GGSASSCGGSSSSCGGGGGSASSCGGGSGSGCGSSSGSSCGSSSGSSCGSSSGSSCGSS
                     SS"
     gene            complement(5001..6327)
                     /locus_tag="C8250_RS31950"
                     /old_locus_tag="C8250_031960"
                     /pseudo=""
     CDS             complement(5001..6327)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055542.1"
                     /locus_tag="C8250_RS31950"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031960"
                     /product="DUF692 domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="DUF692 (E-value: 8.3e-91, bitscore: 302.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDLGTGIGWRPEIADAIAELPGVDWVEVVSENLCADHLPEPLRR
                     LRESGTTVIPHGVSLGLGGAERPDPGRLAALATRIGLLGAPLVSEHIAFVRAGGPLTGS
                     PRLEAGHLLPVPRTRDALDVLCANVRIAQDALPVPLALENIAPLLGWPDEEFSEGEFLY
                     ELVERTGVRLLIDVANLHTNHVNRGEDPVAVLDELPLEAIAYVHVAGGTEKDGVWHDTH
                     AHPVTRPVLNVLAALRERIRPPGVLLERDDNFPSAAELAAELAAIRGVPSAERPQEAHC
                     V"
     gene            complement(6465..7154)
                     /locus_tag="C8250_RS31955"
                     /old_locus_tag="C8250_031965"
     CDS             complement(6465..7154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030616.1"
                     /locus_tag="C8250_RS31955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031965"
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="WP_244809482.1"
                     /transl_table=11
                     /translation="MTSIDRDAAPQFVLPLVVRIEKDDPPARTDALETAARAVLTLLSD
                     ERAAGDGEWAEAVRDWQDARIRKVVRRARGSEWRRAGYLPGITVTGLEAEVRVYPPVPL
                     DGWPKVLAKLQVSGTELDDPEPPPVAEAGLPVLWMNPELDMSAGKAMAQAGHGAQLAWW
                     ELTDAERTAWRDAGFPLAVRTPAPAQWPALTGSGLPVVRDAGFTEIVPGSCTVVSDYLP
                     LRRTTSA"
     gene            7270..8025
                     /locus_tag="C8250_RS31960"
                     /old_locus_tag="C8250_031970"
     CDS             7270..8025
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (137-200). E-value: 5.5e-09. Score:
                     27.9. Matches aSDomain:
                     nrpspksdomains_C8250_RS31960_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007497743.1"
                     /locus_tag="C8250_RS31960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031970"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_244809484.1"
                     /transl_table=11
                     /translation="MDTAAIRVPSELDPVARVERMALPAPGDPPRLWLVNAARHADFAA
                     RLASDVLDPQELRSAAAFRADADRDCYRAAHVGLRLLLGAQLGSAPGNVRLVREDCPGC
                     GGPHGRPAVAGGGVHFSLSHSGSFALLAFAATPVGVDVETVPSDDAVADIASVMHRVEI
                     AELGALEPPERPAAFARAWVRKEAYLKGLGIGLGRDPSADYVGTGETPAAGPAGWSIAD
                     VAVGENRAAAVAVADPGAADITPSAATAH"
     aSDomain        7681..7869
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS31960_ACPS.1"
                     /evalue="5.50E-09"
                     /label="C8250_RS31960_ACPS.1"
                     /locus_tag="C8250_RS31960"
                     /protein_end="200"
                     /protein_start="137"
                     /score="27.9"
                     /tool="antismash"
                     /translation="VGVDVETVPSDDAVADIASVMHRVEIAELGALEPPERPAAFARAW
                     VRKEAYLKGLGIGLGRDP"
     gene            complement(<8139..8603)
                     /locus_tag="C8250_RS31965"
                     /old_locus_tag="C8250_031975"
                     /pseudo=""
     CDS             complement(<8139..8603)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="C8250_RS31965"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031975"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQTGLAFLPAPLVIGTMSLFFSVKLTIRYGTRRVLLTGLAALAIG
                     LVLLSRAPVDGNYWQHVMPTLVIQGFGMGLAVPAVIMRAMSGAAPEDAGLASGLNSTAQ
                     QSGAAVGLAVLATVATSRSNSLLDKGAENISALRDGYSLAFLFSAGFVALG"
     gene            complement(8564..8956)
                     /locus_tag="C8250_RS31970"
                     /old_locus_tag="C8250_031980"
     CDS             complement(8564..8956)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS31970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_031980"
                     /product="hypothetical protein"
                     /protein_id="WP_138354296.1"
                     /transl_table=11
                     /translation="MIAILARRPPPRQGPGAHGLHGHPLQRVGAHLVRLLPPGTPAEQA
                     RGGAVVDTEGTYTAYLNGIGARAVLVRPDFYVFGGTADTEGTPALVDALRDALPEAALT
                     GSAAGPRGCSVSTPCRPDSPSCPHRW"
     gene            8955..9632
                     /locus_tag="C8250_RS31975"
                     /old_locus_tag="C8250_031985"
     CDS             8955..9632
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153329.1"
                     /locus_tag="C8250_RS31975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031985"
                     /product="AIM24 family protein"
                     /protein_id="WP_138354297.1"
                     /transl_table=11
                     /translation="MNSDLFAAENMAKPATEPGMTLENAKSVKYAVNGECYARQGAMIA
                     FRGNLQFEVKGQGVGKFLKRAFTGEGLPLMSVRGTGEAWFAHEAANCFIISLDQGDAIT
                     INGRNVLCFDTTLDYEIKVVKGAGMVGGGLFNSVFTGHGRLGVICEGNPIIIPVSPQSP
                     VYVDTDAVVGWSAHLETSVHRSQSFGSMLRGGSGEALQLMLQGDGFVIVRPSEAKPVQP
                     AAH"
     gene            9634..>10440
                     /locus_tag="C8250_RS43810"
                     /pseudo=""
     CDS             9634..>10440
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088893.1"
                     /locus_tag="C8250_RS43810"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRLERVGRRYGLGGPWVLRDVDLDVPPGSLLRVQGANGSGKSTLL
                     RIVAGVDRPSTGRITGRPATAYVPERFPPALPFDAHGYLVHLGAIHGLRRTTAGRRAGE
                     WLERFGAAGHARTPMDELSKGTAQKIAVVQALLAEPRLLVLDEAWTGLDEAARTVLDDA
                     VRERVAAGGAVVFVDHDAWRLAGEPSGVHRFADGRLTAVAAAGAEADVPRVVVEASGPG
                     EPPALPGTPGYGPAAPGRIRITVPAHESDAVLRALLTADPPWHIRAV"
     gene            10526..11191
                     /locus_tag="C8250_RS43815"
     CDS             10526..11191
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997023.1"
                     /locus_tag="C8250_RS43815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter"
                     /protein_id="WP_232485438.1"
                     /transl_table=11
                     /translation="MTALVRYQAALLIRSQRWLPPVLLYGVIMAIGISSGQPLLDSLAF
                     AAAGMLPVAAWLVRVCVTNEPPAARACAAAAAGPGRVHLSSVLTALLAAGALGAAGVAV
                     VAVISDAHTADRRHVVPLGPAVTAGLLAVLVSALLGLAVGALTNPPVLRRAGWAIPVSG
                     LSALLVLVIGGSPANAAVSGLVSGSQTGTVGLPLVPLCLAAVAAAAATAVACALGSRR"
ORIGIN
        1 gggccgccgg cgtcaccatc gagaccggcg cgccggccag ggagctgcgg cgcaccgcgg
       61 gcggctggca ggtcaccgtc ggcgaccggg tgctcgacgc ggacgccgtc ctgatcgccg
      121 cgcccgcccc ggccgccgcc cggctgctgg cggccgagtc acccgtcgcc gccgcggagc
      181 tgtcggcggt ggagtacgcc agcatggcgc tggtcaccat ggcgttccgg cggcgcgacg
      241 tgctgcggat gccgaagggc accggcttcc tggtgccgcc ggtcgacgga aagacgatca
      301 aggcgtccac cttctcctcc cacaagtggg gatggatcaa cgaggccgga cccgacacct
      361 tcctgctgcg cacctccgtc ggccggcacg gcgacgaggc ggacctggcc tgggacgaca
      421 ccgatctcgt ccgcctgtcg cggcgcgacc tgggcgaggc catcgggctg tccgcggcgc
      481 ccgtcgcggc ccgtgtcacc cgctgggacg gcggactgcc gcagtacccg gtcggtcatg
      541 tcgagcgcgt cgccaggatc cgcgagcagg tcgggaagct gccggggctc gcggtctgcg
      601 gcgcggtgta cgacggggtc gggattccgg cctgtgtcgc cagcgcccgc aaggcggccg
      661 acgaggtact gacctccctg gccacgaccc tggcgacagg cggcgcgcgg gacacgggag
      721 aatgacggca tgactgactc gactgctgct cccgacgccc cggacaggac tccgaacgcc
      781 ggcaagaagg cgaaggatct caacgagatc atccgctaca ccctctggtc cgtcttccgg
      841 ctgcgcgacg tgctgcccga ggaccgctcc ggatacgccg acgaggtgga ggagctgttc
      901 gcgcagctcg ccgcgaagga cgtcacggta cgcggcacct acgacgtgtc ggggctccgg
      961 gcggacgccg acctcatgat ctggtggcac gcggagaccg cggaggcgct gcaggaggcc
     1021 tacaacctct tccgccgcac ccggctcggc cgcgcgatgg tcccggtctg gtcgaacatg
     1081 gcgctgcacc gccccgcgga gttcaacaag tcgcacgtcc cggcgttcat cgccgacgag
     1141 accgtgcgca agtacgtcag cgtctacccg ttcgtgcgct cctacgactg gtacctgctg
     1201 cccgacgagg accgccgccg gatgctcgcc gaccacggca agatggcgcg cggcttcccg
     1261 gacgtgcggg ccaacaccgt cccggccttc acgctcggcg actacgagtg gatcctcgcc
     1321 ttcgaggcgg acgaactgca ccgcatcgtc gacctgatgc ggcacctccg cgcatccgag
     1381 gcacggatgc acgtacgcga ggaggtgccg ttctacaccg ggcggcgcaa ggagatcggc
     1441 gagctggtgg ccggcctggc gtaaggctgg cgctacggct tgggctcggg atgcggaccg
     1501 cacgtcggcg tgcggtccgt tcccgtttca ccgcgcagga gatacgcgtc gacgcggttg
     1561 ttgacgcaag tgttggagcc gtacgccacg ccgtgcgagc cggagcggcg ctcggtgagg
     1621 agcacggaac ggggcagccg gcgctggagt tccacggcgc ccgcgtgcgg ggtcgcggcg
     1681 tcgcgctcgg cggagacgag gagcaccggc ggcagttcat ggccgaacgt gcgcacctcc
     1741 aggggctgcc ggtgcggtcc cttccagaag gcgcacggca ggttcatcca ggcgttgtcc
     1801 caggtctcga agggggcggt gcgggccagc gcggtgttgt cgcggtccca ggtgaaccag
     1861 tcgcgcggcc agggcgagtc ggcgcactcg acggccgtgt agaccgcgtt gccgttctcg
     1921 ttctcgacgg ccctggcggg gttgggggag gcctcggtga tcagcggctt cgggtcgccg
     1981 tggacatacg cggacagggc tgcggccagc tccggccagg tgtcgtcgta gtacccggcg
     2041 cccaggtagg cggcctgcag ctggccgggg ccgaccacgc cgcccgccgg ccgcacggcc
     2101 agctcggcgc gcaccgcgtc gtaggcctcc tgcacctgcg tccggtcggt gcccaggtgg
     2161 tacgcggagt cgtacttggc cacccagtcg cgccagtcgg cccagcggat ctcgaaggcg
     2221 gcgtcctgct ccaggttggc ctggtaccag atctggcgcg ggtcgggatc gacgacgctg
     2281 tcgaagacca tgcggcgcac atgccggggg aagagcgtcg cgtacaccgc gccgaggtac
     2341 gtgccgtagg acgcgccgta gaagttgagc ttgcgttcgc cgagcgcggc gcggatgaca
     2401 tcgaggtcgc gggcgctgtt gagcgaggtg aggtacggca gcagatgccc ggagcgccgc
     2461 tcgcagcctt cggcgtacgc cttcgcgtct tcgatccggg cctgcttgtc gcgctcgctc
     2521 gtcggccgtg ggtcgcgggt gggggccttg acgtagtccg ccggggcttc gcaggagatg
     2581 ggcgcggacc ggccgacccc gcgcgggtcg aagcccacga agtcgtaggc gcgggcggcc
     2641 ttggcgtact ccttgacctt caggacgctg aacagcggga agtacagccc cgagccgccg
     2701 ggtccgccgg ggttgtagac cagggcaccc tgccgctcgc cggccggccc ggtggcggcg
     2761 acccggctga tgaccaggtt gatccgctcg ccgtccggcc gggcgtagtc cagcggtact
     2821 gacacggtgc cgcaccggac cgaggcgggc agccgggtcg cgccggcgca cctgccgaac
     2881 gtcaccccgg ccagagcggc gcgctcggcg gcgacggccg cgccgcgcgc ctcggccacc
     2941 cggtcgccgt gcggcggtcc cggcgccgcc gatccggggg gagcgatggc cagggtgctc
     3001 agcgccaggg ttcctgcgac gccgtacagg gcaattgatc gcaccgatga tcctctcgtg
     3061 tcaggtcatg acaaaaggga tccttggggc ggtggtggat gaagtaaagg acaagcggcg
     3121 ggtgtcgtcc ccgaccaccc cggccggggt ggtcagccga gcgcggcccg ctgcgccggg
     3181 tccagcagcg cggccgggcc gcgcaccgcc agcgcgctga gcgggccggg gccgtccgga
     3241 acggcgcgca gcgcgtcctg cccggcaggg gaggcccagc gggtgtacgg atggacctcc
     3301 acgcgggcga tgatccagca cccggtggtc agcagcagcg gcagcgcgaa ccaggcctgc
     3361 gcctggccac cgtcgggctg cccgcccgcc gacaggacca gggcggcgcc ggccatcagc
     3421 aggttcagga gtatggcgcc gcgcacctgc cggatcccgg cggtgacgct ctcccgggcc
     3481 gccgccggca ccgcgaggcc gtcgcccacg agccgttccc cgagggcgcg gatggcgccg
     3541 gccgcggcgt gcgccacccg tatcgcggcg accggggact ggccgtccgg cccgatggag
     3601 gcgatcagcg accgttcgag atcgtcacgg ccctcggcgt cgaccactgt cgcccacccg
     3661 gtgtgcgcga gcagcagccg ctgctcgccc gccatcgaga ccagcgtcag atcggtgacc
     3721 cggcgcggtc cgccggacag gaacgccgtc tcgtacagcc cgagtccggc gacctggggc
     3781 cggccgccgg gcccggctgc gggcagagcg cccgcggcga tcgcggcccg gcacagacgc
     3841 gcgcaggaga cgaccgccgc gacgcacgcg acgagaagga acagcatcca cataagggat
     3901 ttctactcga cggtagtgac actccgccgg gaatttcgcg gatcgacccg tgcggcggcc
     3961 ggcccgttac gaactgctgc tgccgcaact ggatcccgag ctggatccgc agctggaacc
     4021 ggaactcgaa ccgcagctcg accccgaact cgaaccgcaa ccggatcccg agccgccgcc
     4081 gcagctcgac gcggatccgc ccccgccacc gcagctcgac gacgaccctc cgcaactcga
     4141 agcggaacca ccgcagctgg tgccgccgcc ggcccagccg cccgcggcat cgccccacga
     4201 gcccgggtcg gacgcgtcgg acgacggctg cgaggactgc gccaactggt cgcgcaggac
     4261 ggtgtcctgg atcgaggcgg caccggccag cgcgaacagc atggtggcgt ccgagccggt
     4321 ggaggcggtg cgggaggcca gcagcggacg gttgctgagc cgcagcccgt gcagcacccg
     4381 cttgccggcc ggtgtgagcc ggccgcgcgg cgccgagcac gtcaggagga cgaagagccc
     4441 gacggcgagc cccggcagca cccggacgaa cagcggcagc cctgaaccga cgacgaggtg
     4501 cggcatcacc tccgccagcg acaggaacag cagcaggcac cagacggtct tgtgcagcgt
     4561 cgacacccgc cgccatctgc ggtgcacctc gggctggaag aacaggccgc ggcgggcgag
     4621 ccggtcgccg atcgactgca ccggagatcc ggtcagcacc gctgtacgga cctggcgcag
     4681 gccgccgccc cactcggcgc cgcaggcctc cagcagggcg gtctcgaccg gattcgatgc
     4741 gaccggccgg agcacggtca gctgtcctga agcgtccacg gcgatccggc cgtccgcgtg
     4801 catcgccgcg atcacggtgt cggcgacccg gcccggaccg ccggccagga aggcggtctc
     4861 cagcggatcc cgggggatgt cgccgtggta cggccgggtg aagcggcggg cgcggatctt
     4921 ctccccgacg aggtacgccg aggtggcggc gatcagcagg tacacggtga gcatgaggcc
     4981 ggtcatgacg ttcatcgagg tcaccttccc ggcagcgcgg tgcgcgcggc gtccatgatc
     5041 cggccgaacc ggccgaaccg gccgaaccgt ccggtccgca cgaggcggcc ggggcgggcg
     5101 gccgcggaca gcggcgcggg acccgagcgc tcccgccacc agccgtccag cagacggcgg
     5161 gtggcgtcgt cgagcgcttc cgcgtcatcg tccagcacat gctccgcgaa gcacagcgcg
     5221 tcgaggcggt agccgccctg cagcgggtgc gtggccgcgt accgcaggaa ggcgggacgg
     5281 tagcggtcgc cgaggatttc cggcagttcc ggggccacct tggcggtcac atcggcgcgc
     5341 ttggccgcga gggcccgcga ctggacgccg atccggccgc ggtcgaaacc ctccgggacg
     5401 ggggtgcccg ccaccagcgc ggagagcagc gccgtctgcg cgagcgcgag ccgctgccgt
     5461 gcggcggcgc tgtcggcgtc agacacagtg cgcctcctgg ggccgctccg ccgacgggac
     5521 accgcggatc gccgcgagtt ccgcggcgag ttcggccgcg gacgggaagt tgtcgtcccg
     5581 ctccagcagg acgcccggcg gccggatccg ctcgcgcagc gccgcgagca cgttcagcac
     5641 cggccgggtc accggatggg cgtgcgtgtc gtgccagacg ccgtccttct cggtcccgcc
     5701 cgccacatgg acgtaggcga tggcctccag cggcagttcg tcgagcaccg cgaccgggtc
     5761 ctcgccccgg ttcacatggt tggtgtgcag attggcgacg tcgatgagca gccgtacgcc
     5821 ggtgcgctcc accagctcgt acaggaactc gccctcgctg aactcctcgt cgggccagcc
     5881 gagcagcggc gcgatgttct ccagcgcgag cggcacgggc agcgcgtcct gcgcgatgcg
     5941 gacgttcgcg cagagcacgt cgagcgcgtc gcgggtgcgg ggtacgggca gcaggtgccc
     6001 ggcctccagc cgcggcgaac cggtcagcgg cccgccggcc cgcacgaacg cgatgtgctc
     6061 gctgacgagc ggcgccccca gcagcccgat ccgcgtggcg agcgccgcca gccggccggg
     6121 gtcggggcgc tccgcgccgc ccaggcccag cgagaccccg tgcgggatca ccgtcgtgcc
     6181 gctttcgcgc agccgccgca gcggttccgg gaggtgatcg gcgcagaggt tctccgagac
     6241 gacctccacc cagtcgacac cgggcagctc cgcgatcgcg tccgcgatct ccggccgcca
     6301 gccgatacct gtacccaagt ccttcatgcc gtccccctcc gcgtttcccg cacacgccgt
     6361 gccggggtga tggccccgcc gggaccgggc gaaccctgtg ggtggccggt tcagagcttg
     6421 atttgaggtt cccgtgccgg tgcgggcccg tcgcccgccc ggtgtcacgc gctggtggtg
     6481 cggcgcagcg ggaggtagtc ggagacgacg gtgcaggagc cggggacgat ctcggtgaaa
     6541 ccggcgtcgc gcaccacggg caggccggag ccggtgagcg ccggccattg ggcgggcgcc
     6601 ggagtgcgga ccgcgagcgg gaaaccggcg tcgcgccacg cggtgcgttc ggcgtccgtc
     6661 agttcccacc aggcgagctg cgcgccgtgg cccgcctggg ccatggcctt gcccgcggac
     6721 atgtcgagct ccgggttcat ccagagcacc ggcagcccgg cctccgccac gggcgggggt
     6781 tccggatcgt ccagttcggt gcccgagacc tggagcttcg ccagcacctt gggccagccg
     6841 tccagcggga ccggcggata gacccgtacc tcggcctcca gcccggtcac ggtgatgccc
     6901 ggcagatatc cggcccggcg ccactccgag ccgcgcgccc ggcggacgac cttgcggatc
     6961 cgggcgtcct gccagtcgcg taccgcctcg gcccattcgc cgtcgcccgc ggcccgttcg
     7021 tcggacagca gggtgagcac ggcgcgcgcc gcggtctcca gggcgtcggt gcgcgccggc
     7081 gggtcgtcct tctcgatgcg gacgacgagc gggaggacga actggggcgc cgcgtcgcgg
     7141 tcgatgctgg tcacggccac agtctgccac cgagcagggc gccggacgcg ttcggtccgc
     7201 cggggctcgc cgccgcgccc gccatcgggt ccgcccagcc gggaaccgcc gacgatctac
     7261 gatgaccggg tggatacggc cgcgatacgc gttcccagcg agctcgaccc ggtggcacgg
     7321 gtcgagcgga tggcgcttcc cgcccccggc gacccgccgc ggctgtggct ggtgaacgcg
     7381 gcccggcacg ccgacttcgc ggcgcggctg gcgtccgacg tcctcgaccc gcaggaactg
     7441 cgcagcgccg cggcgttccg cgccgacgcc gaccgggact gctaccgcgc cgcgcacgtc
     7501 ggactgcggc tgctgctcgg cgcccagctc ggcagcgccc ccggaaacgt acggctggtc
     7561 cgggaggact gcccggggtg cggcgggccg cacggccgtc ccgccgtggc gggcggcggt
     7621 gtgcacttct cgctgtcgca cagcggcagc ttcgccctcc tggcgttcgc cgcgaccccg
     7681 gtgggggtgg atgtggagac cgtcccgtcc gatgacgcgg tggcggacat cgcctccgtg
     7741 atgcaccggg tggagatcgc cgaactcggc gccctggagc cgccggagcg gcccgccgcc
     7801 ttcgcgcggg cgtgggtgcg gaaggaggcg tacctcaagg ggctgggcat cggtctcggc
     7861 cgcgacccct cggcggacta cgtggggacc ggcgagacgc ccgcggccgg cccggcgggc
     7921 tggtccatcg ccgacgtggc cgtgggggag aaccgcgccg ccgcggtcgc cgtggccgac
     7981 ccgggcgcgg cggacatcac gccctccgca gccaccgcgc actgaaccgg cgctccgttc
     8041 tggacgggac cggcgtcctg ctggtcctgg gccgtctcca cctcgggagc cggctccgtc
     8101 ttcggggcgt ccttgaggat gaagtacgtc gccaggaagc ccagcgccac gaacccggcg
     8161 gagaacagga aggccaggct gtagccgtcc cgcagtgccg agatgttctc cgcgcccttg
     8221 tcgagcaggg agttgctgcg cgaggtggcc acggtcgcca ggacggcgag gccgacggcg
     8281 gcaccggact gctgggcggt gctgttgagg ccggaggcga gaccggcgtc ctcgggagcg
     8341 gcgccggaca tcgcccgcat gatcacggcc gggaccgcga gacccatacc gaagccctgg
     8401 atgacgagcg tcggcatcac gtgctgccag tagttgccgt cgaccggtgc gcggctgagc
     8461 aggaccaggc cgatggcgag ggccgcgagt ccggtcagca ggacccggcg ggtgccgtag
     8521 cggatggtga gcttcacgga gaagaacagc gacatcgtgc cgatcaccag cggtgcgggc
     8581 aggaaggcga gtccggtctg catggagtcg aaaccgagca cccgcgcggc cccgctgcgc
     8641 tgccggtgag cgccgcctcg ggaagggcgt cgcgcagggc gtccacgaga gcgggcgtgc
     8701 cctccgtgtc cgcggtgccg ccgaagacgt agaagtccgg gcggaccagg acggcacgcg
     8761 ccccgatgcc gttcagatac gccgtgtacg tgccctcggt gtcgacgacc gcgccgccgc
     8821 gcgcctgttc ggctggcgtg ccgggcggca gcagccgcac caggtgcgca ccgaccctct
     8881 gcagcgggtg cccgtgcagg ccatgggccc cagggccttg gcggggaggg ggtcggcggg
     8941 cgaggatggc gatcatgaac agtgaccttt tcgcggccga gaacatggcc aagccggcca
     9001 ccgagcccgg tatgaccctg gagaacgcca agtccgtcaa gtacgcggtg aacggcgagt
     9061 gttacgcccg ccagggtgcg atgatcgcct tccgcggcaa cctccagttc gaggtgaagg
     9121 gccagggcgt cggcaagttc ctcaagcgcg ccttcaccgg cgagggactg cccctgatgt
     9181 ccgtacgcgg cacgggcgag gcgtggttcg cgcacgaggc ggccaactgc ttcatcatca
     9241 gcctcgatca gggcgacgcc atcacgatca acgggcgcaa cgtgctctgc ttcgacacca
     9301 cgctcgacta cgagatcaag gtggtgaagg gcgcgggcat ggtcggcggc ggcctcttca
     9361 acagcgtctt caccggccac ggccggctgg gtgtgatctg cgagggcaac cccatcatca
     9421 tccccgtcag cccgcagtcg ccggtctacg tcgacaccga cgcggtcgtc ggttggagcg
     9481 cccacctgga gacctccgtg caccgctcgc agagcttcgg ctcgatgctg cgcggcggtt
     9541 caggcgaagc gctgcagctc atgctgcagg gcgacgggtt cgtcatcgtc cggccgagcg
     9601 aggccaaacc cgtccagccg gccgcccact gacatgaggc tggagcgcgt cggccggcgc
     9661 tacggcctcg gcgggccctg ggtgctgcgg gacgtggacc tcgacgtgcc accgggttcg
     9721 ctgctgcgcg tccagggcgc caacggcagt gggaagtcga cgctgctgcg catcgtcgcc
     9781 ggcgtcgacc ggccgtccac ggggcggatc accggccgcc ccgcgaccgc gtacgtgccc
     9841 gaacgcttcc cgcccgcgct gccgttcgac gcccatggct acctcgtcca cctcggcgcg
     9901 atccacgggc tgcgccgcac cacggcaggc cggcgcgcgg gggagtggct ggagcggttc
     9961 ggggccgccg gccacgcccg caccccgatg gacgagctgt ccaagggcac cgcccagaag
    10021 atcgccgtcg tccaggcgct gctcgccgag ccgcggttgc tggtcctgga cgaggcgtgg
    10081 acgggcctgg acgaggcggc ccgcacggtc ctcgacgacg cggtgcgcga acgggtcgcg
    10141 gcgggcggtg ccgtcgtctt cgtcgaccac gacgcgtggc ggctcgcggg cgagccgtcc
    10201 ggcgtccacc ggttcgcgga cggccggctc accgccgtag cggcggccgg cgcggaagcg
    10261 gacgtcccac gggtggtcgt cgaagcgtca ggccccggtg aaccgcccgc ccttccgggc
    10321 actcccggct acgggcccgc cgcaccgggc cggatccgga tcactgtccc ggcccatgag
    10381 tccgacgcgg tcctgcgcgc gctgctcaca gccgacccgc cctggcacat ccgggccgtc
    10441 cggccggagc cgggaccggg ggccgcgggc ccggagaccg gtcccggctc cggccggggc
    10501 ccgccgacac ccggggagac accggatgac cgcccttgtc cgctaccagg ccgcgctgct
    10561 gatccgctcc cagcgctggc tgccgccggt gctgctctac ggggtgatca tggccatcgg
    10621 gatctcgtcg gggcagccgc tgctcgactc gctggccttc gccgccgccg gaatgctccc
    10681 cgtcgccgcc tggctggtgc gggtgtgcgt caccaacgag ccgcccgccg cgcgggcctg
    10741 tgccgccgcg gcggccggac cgggccgcgt gcatctgtcg agcgtgctga cggcgctgct
    10801 cgcggccggt gccctcggcg ccgccggggt ggcggtggtc gcggtgatca gcgacgcgca
    10861 caccgccgat cgccggcacg tggtcccgct cggaccggcg gtcacggccg ggctgctggc
    10921 cgtgctcgtc tccgcgctgc tcggcctcgc ggtcggcgcg ctcaccaacc cgccggtgct
    10981 gcgccgcgcc ggctgggcga tcccggtctc cggactgagt gccctgctgg tgctggtcat
    11041 cggcggctcg cccgccaacg ccgccgtgtc gggactggtc agcggctcgc agaccggcac
    11101 ggtcgggctg ccgctggtgc ccctgtgcct ggcggcagtc gcggcggccg cggcgaccgc
    11161 ggtcgcctgt gcgctcggtt cacgccgctg acgatccggc ctccagccgc cggccgggcc
    11221 cggggggcgg gccgtgccgg tccggcgggc cgaactccgg cccggtcacc gcccgctggg
    11281 ccgcccgtgc cagcgaacgg cggtcgtggt gggcaccggg cgggatc
//
