LOCUS       NZ_CP048835            13021 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7054512
            Orig. end                         :: 7067533
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13021
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="17"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13021
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13021
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8021](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8021
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            complement(376..756)
                     /locus_tag="C8250_RS31560"
                     /old_locus_tag="C8250_031570"
     CDS             complement(376..756)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS31560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_031570"
                     /product="hypothetical protein"
                     /protein_id="WP_138356531.1"
                     /transl_table=11
                     /translation="MAAWALAGIHGALAGFLAAYLVLLAPVSCHAGTGPGPDLLRLFVH
                     TPAILIAAVATALGTFALAVRITLSAPLAVRLTVPPLLLCTALALLVWADFAWFGAVAG
                     VPNPGLCPADNVPPWWPHWIPA"
     gene            complement(855..1694)
                     /locus_tag="C8250_RS31565"
                     /old_locus_tag="C8250_031575"
     CDS             complement(855..1694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563246.1"
                     /locus_tag="C8250_RS31565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031575"
                     /product="PaaX family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_138356532.1"
                     /transl_table=11
                     /translation="MTEHTPSSLIVTFFGAYGRAELDGRVPVAALIRLMGAVDVDPQSV
                     RSAVSRLKRRELLVPDRVGGAAAYALSDDARQLLADGDRRIYGGPGSAEGDGNSDGDGS
                     WVLAVFSVPETERHKRHLLRSRLARLGFGSAAPGVWIAPAHVQEEARHTLRRLELDSYV
                     DLFHGTHLGFEPTATAVRRWWDLDAIAKLHRTFLDAHEPVLDRWSRRPDVPPRDAFPDY
                     LRALDSWRQLPYADPGLPTALLPPDWPGARASQVFTELHQRLHAAGAAFVRAAPGPA"
     gene            complement(1699..3318)
                     /locus_tag="C8250_RS31570"
                     /old_locus_tag="C8250_031580"
     CDS             complement(1699..3318)
                     /NRPS_PKS="Domain: AMP-binding (49-442). E-value: 2.6e-84.
                     Score: 275.1. Matches aSDomain:
                     nrpspksdomains_C8250_RS31570_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840191.1"
                     /locus_tag="C8250_RS31570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031580"
                     /product="AMP-binding protein"
                     /protein_id="WP_138356533.1"
                     /sec_met_domain="AMP-binding (E-value: 6.2e-91, bitscore:
                     304.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLLPSAHVDTFARDHLPPRDQWPELAFELPALHYPDRLNCAAEL
                     LAGGSPGAPCLRTPGGEVWSYEDLNATAARIAHVLADDLGVRPGNRVLLRGPTTPWLVA
                     CWFAVLKAGAVAVTVLAAQRSGELATICDIAAVRHALCDLRSVDDLAKAEIPDLRITTY
                     GGEAPEDLLRRAADKPDHFTDVATSSDDVALIAFTSGTTGRPKGCMHFHRDVLAIADTF
                     SAQVLCPRADDVFAGSPPLGFTFGLGGLVIFPMRAGASSVLLEQAGPEQLLAAVARHRV
                     SVLFTAPTAYRAMLGHLNDASSSASYDVSSLRRCVSAGENLPAATWQAWHDRTGLRIIN
                     GIGATELLHIFISAADDAIRPGTTGLPVPGYRARIVDAAGEPVPDGEPGLLAVRGPTGC
                     RYLADERQTVYVQGGWNLTGDTYVREPDGYFRYVARADDMIISAGYNIAGPEVEEALLR
                     HPDVSEAAVIGVPDEERGQIVRAFVVLRDGVPRGTATVGALRDFAKGVIVPYKCPRDIV
                     FLDALPRTPTGKLQRFRLRDLE"
     aSDomain        complement(1993..3171)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS31570_AMP-binding.1"
                     /evalue="2.60E-84"
                     /label="C8250_RS31570_AMP-binding.1"
                     /locus_tag="C8250_RS31570"
                     /protein_end="442"
                     /protein_start="49"
                     /score="275.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="SPGAPCLRTPGGEVWSYEDLNATAARIAHVLADDLGVRPGNRVLL
                     RGPTTPWLVACWFAVLKAGAVAVTVLAAQRSGELATICDIAAVRHALCDLRSVDDLAKA
                     EIPDLRITTYGGEAPEDLLRRAADKPDHFTDVATSSDDVALIAFTSGTTGRPKGCMHFH
                     RDVLAIADTFSAQVLCPRADDVFAGSPPLGFTFGLGGLVIFPMRAGASSVLLEQAGPEQ
                     LLAAVARHRVSVLFTAPTAYRAMLGHLNDASSSASYDVSSLRRCVSAGENLPAATWQAW
                     HDRTGLRIINGIGATELLHIFISAADDAIRPGTTGLPVPGYRARIVDAAGEPVPDGEPG
                     LLAVRGPTGCRYLADERQTVYVQGGWNLTGDTYVREPDGYFRYVARADDMIIS"
     CDS_motif       complement(2683..2742)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS31570_0001"
                     /evalue="7.40E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="C8250_RS31570"
                     /protein_end="212"
                     /protein_start="192"
                     /score="21.7"
                     /tool="antismash"
                     /translation="ALIAFTSGTTGRPKGCMHFH"
     gene            3417..4532
                     /locus_tag="C8250_RS31575"
                     /old_locus_tag="C8250_031585"
     CDS             3417..4532
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175801.1"
                     /locus_tag="C8250_RS31575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031585"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_138356534.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 9.7e-07, bitscore:
                     28.4, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-22, bitscore:
                     78.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-47, bitscore:
                     160.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAFALDPEQLKWCAEVRSLAAGRLRPLAEAGEPGRVNRPLLAEL
                     GELGLLERVFPPGGKVSAMDLCLLRESLARECTEAETALALQGLGAHPVLHNAELAARW
                     IPEVTAGRAVAAFALTEPAAGSDAAALELAAEPDGTGWRLTGEKCWISNAPQADFYTVF
                     ARTTPGAGSRGVTAFLVPAGRPGLSGEHLDMLSPHPIGRLAFDGVPVGPGDLLGEPGRG
                     FRVAMGTLNLFRPSVGAFAVGMAQAALDAATEHAGGRTAFGGPLKDLQAVSHALAETAT
                     RTEAARLLVYAAAEAYDSGAPDIAKRSAMAKLYATETAQFAVDRAVQIHGARALERGHL
                     LEHLYREVRAPRIYEGATEVQRTIIAKELYR"
     gene            4529..4927
                     /locus_tag="C8250_RS31580"
                     /old_locus_tag="C8250_031590"
     CDS             4529..4927
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563243.1"
                     /locus_tag="C8250_RS31580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031590"
                     /product="RidA family protein"
                     /protein_id="WP_138356535.1"
                     /transl_table=11
                     /translation="MSLRRINPGELSPPTGFSHAVTATGRTMVFLAGQTALDQAGKIVG
                     DTLPAQFELALTNLLAALAAAGGGPADLARITVHTTDVAAYREHAAELGRLWRSLAGRD
                     YPAMAVVGVVRLWDEEALVELDGIAVLA"
     gene            5001..6206
                     /locus_tag="C8250_RS31585"
                     /old_locus_tag="C8250_031595"
     CDS             5001..6206
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642316.1"
                     /locus_tag="C8250_RS31585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031595"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_138356536.1"
                     /sec_met_domain="DAO (E-value: 1.5e-69, bitscore: 234.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRHSLDVVIVGAGVVGAACAYYASRSGLSVAVVDRGSVAGGTT
                     GAGEGNLLVSDKEPGPELDLALLSTRLWRELADELPPEIEFESKGGLVVASDEARLDAL
                     STFAAQQTAAGVTAARVPADRLHEFEPHLAPGLAGAFHYPQDAQVQPALAAAHLLRAAR
                     RAGALLCLGEEVTAVLTGPGGAVRGVRTDRGELSAPAVVNAAGTWGGELAALAGVDLPV
                     MPRRGFVLVTEPLPRIVRHKVYAADYFADVASGSAALQTSPVVEGTPSGPVLIGASRER
                     VGFDRTLRVEVLRRLAAGAAGLFPVLAGVRVMRAYHGFRPYLPDHLPAIGPDPRAPGLF
                     HACGHEGAGIGLAPATGLLLTAAIRGQRPALDLAPFRPDRFSRRGPDSRRGTGRTRGPE
                     RT"
     gene            6209..6523
                     /locus_tag="C8250_RS31590"
                     /old_locus_tag="C8250_031600"
     CDS             6209..6523
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091458.1"
                     /locus_tag="C8250_RS31590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031600"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_138356537.1"
                     /sec_met_domain="Fer2_4 (E-value: 4.4e-23, bitscore: 80.1,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARNPVELAGATPEPSFEITMDGRVLPALPGQSIAAALWSAGILA
                     WRTTRVNGRPRGAFCGIGSCFDCLATVNGAPNQRACLVPARPGDLVTTQEGHGRADLAV
                     "
     misc_feature    6254..6267
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            6504..8021
                     /locus_tag="C8250_RS31595"
                     /old_locus_tag="C8250_031605"
     CDS             6504..8021
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606671.1"
                     /locus_tag="C8250_RS31595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031605"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_138356538.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.5e-24, bitscore:
                     85.0, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 3.1e-12, bitscore:
                     45.7, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPISPSEPPVPPEYDLAIVGAGPAGLSAAVAAADLGLSVVVLDAA
                     AAPGGQYYRHPAPGLGAARPEALHHGWAAFAALVRRLGRHTGTGKVRHLTHHHVWTVER
                     GSSTAWTVHAVTGPDGPEQGRAAVTSRALLLATGSYERQLPFPGWTLPGVVGAGGAQAM
                     LKSGLVLPGRRIVVAGSGPLLLAVAGSLAAAGAKVPAVVEAAGYTAYAGSPRTLAANPG
                     KLLEGAVHGAALLRHGLRPRTRSAVTEAHGTDRVEAVTVSRLDRDWRPVPGTGRRIACD
                     ALAVGHGLVPQLELATGLGCATHRTPDGTYALALDDSQRTSVPGVWAAGEAGGVGGAQL
                     ALAEGELAAFAIAAVSRSAVRPDARRAVALRRTRARLRAFAAVMAAAHRPGPGWPDWLS
                     DDTDVCRCEEVSAGEVRAAVTDLGAHDARTVKLFTRAGMGWCQGRMCGPAVDCLARADS
                     HADADADADADADADAGPDRRPLSCPVPLAALSRPAALSGPDGPPRS"
     misc_feature    8079..8095
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.6"
                     /tool="antismash"
     misc_feature    8083..8093
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            8161..9024
                     /locus_tag="C8250_RS31600"
                     /old_locus_tag="C8250_031610"
     CDS             8161..9024
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514377.1"
                     /locus_tag="C8250_RS31600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031610"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_138356562.1"
                     /transl_table=11
                     /translation="MVATALPFHADLRVDHDGYAEHVAWLIESGCDGVVPNGSLGEYQT
                     LTDDERARVVRTAVEAAGDGDRVMPGVAAYGSDEARRWAEQAGEAGAGSVLLLPPNAYR
                     ADERAVRAHYAEVARAGLPVVAYNNPYDTKVDLTPQLLAELYNEGSIVAVKEFTGDVRR
                     AYEIAELAPGLDLLVGADDVLLELGIAGAVGWIAGYPNAFPEACATLYRAALSGDLDTA
                     VPLYRALHPLLRWDSKPEFVQAIKVSMDLVGRPGGPVRPPRSPLPADIEAVVRAATEKA
                     MAEGLG"
     gene            9117..10118
                     /locus_tag="C8250_RS31605"
                     /old_locus_tag="C8250_031615"
     CDS             9117..10118
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891275.1"
                     /locus_tag="C8250_RS31605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031615"
                     /product="proline racemase family protein"
                     /protein_id="WP_138356539.1"
                     /transl_table=11
                     /translation="MRSRNIYHAVDSHTEGMPTRVITGGVGVIPGATMAERRLYFMEHH
                     DRVRTLLMYEPRGHSSMSGAILQPPTRPDADYGVLYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVPVTEPVTTVRLDTPAGLVTVDVQVEDGEATAVTLRNVPAFSAGLDLKVDVPGHGT
                     LTYDLAYGGNFYAMLPLADLGLPFDRERKNDILAAGLAVMEAINAADRPVHPEDPDING
                     VKHVQLIAPGSDARLSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTDFVNES
                     FIGTFFTGRLVEETTVGGLPAVVPTVTGRAWITGTAQYFLDPSDPFPGGFLL"
     gene            10207..11136
                     /locus_tag="C8250_RS31610"
                     /old_locus_tag="C8250_031620"
     CDS             10207..11136
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038315.1"
                     /locus_tag="C8250_RS31610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031620"
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_244809474.1"
                     /transl_table=11
                     /translation="MTLPHLDATAIARLLGPADAADAVEAVLRGGLDPETGPPRTGVPV
                     PAGELLLMPAATKDFAGVKIAGVAPGNPARGLPRITGSYLLLDGATLQPVALLDGPALT
                     SLRTPAVSAVAIRHLAVPDASHLVLFGAGPQAYGHLAAALAVRPLTRLTVVARRPEPAQ
                     ALVAHARRLGLDAVTGGPDAVAKADLVICCTTARTPLFDGSTVAGHTTVVAVGSHEASA
                     RETDTALVTRATVVVEARSAALREAGDILVPIAEGAYRPEDLAGTLADLVAGRLRPEAG
                     RPRFFKGTGMAWQDLAVAAEIFRAAKAT"
     gene            11178..11900
                     /locus_tag="C8250_RS31615"
                     /old_locus_tag="C8250_031625"
     CDS             11178..11900
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237887.1"
                     /locus_tag="C8250_RS31615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031625"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_138356540.1"
                     /transl_table=11
                     /translation="MGDLKQRNLITAQERLRDQVGHALRAALIAGELRPGVVYSAPALA
                     ADFGISATPVREAMLDLAREGLVEPVRNKGFRVTEMNERDLDQYTEIRALIEVPTVGRV
                     TRTATPEQLEELRPAAEEIVAAARAHDLIGYLEADRRFHLTLLGLAGNERLVEAVGDLR
                     KRSRLYGLTRLDERGELVSSAEEHIELLDLMIFGDAEAAEECMARHLGHVRSLWAVGKE
                     EPAAAKPEPVLKRKLGKA"
ORIGIN
        1 ccgccgtgta ggccatgtcg cccagaacgt cgtacgcctg cagctcgaac acgtacgaag
       61 tgcagtcgga gaagcttttc ccgagggagc tgaagagctg gtcgatctcc tgctgaccgt
      121 tggcattgcg ccacgccccc aggacgctga cgggctcgtt gcgtgaccag agcgcccggc
      181 ggggagccgg atcgccgttg tgcagcgcac gttccgcctc gtacaggtcg gtcttcaccc
      241 acgccaggaa atcgtcgcgg tcgctcatgc cttcatcatg cacccgtcga tgaggggtgg
      301 cacggtcagc catcggcgct gcgcacggca tggatacgcc gacggcgccg acatcacctg
      361 ccccggcacc cgcgctcagg ccggtatcca gtgcggccac cacggaggga cgttgtccgc
      421 ggggcagagc ccggggttgg gtaccccggc gaccgctccg aaccacgcga agtcggccca
      481 gacgagcagc gcgagcgccg tgcagagcag caagggcggc acggtcagcc ggacggccag
      541 gggcgcggag agggtgatgc gcaccgccag ggcgaaggtg ccgagcgcgg tcgcgacggc
      601 cgcgatcagg atcgccgggg tgtggacgaa cagccgcagg aggtcgggac ccgggcccgt
      661 cccggcatgg cacgagaccg gggccagcag gaccaggtag gcggcgagaa agccggcgag
      721 cgcaccgtgg attcccgcga gtgcccaggc ggccatgcgg tggcgggagc cgaagggcgt
      781 gaacctgccg ggtggtgaag gtgtccgcat ggggcgggag acggtgtgcg gtacccgacg
      841 gttccccggc ccgctcaggc gggcccggga gccgcgcgga cgaaggcggc acctgctgcg
      901 tgcaggcgtt ggtgcagttc ggtgaagacc tgggaggcgc gggcgcccgg ccagtcgggg
      961 ggcagcaggg cggtggggag gccggggtcg gcgtagggga gttggcgcca ggagtcgagg
     1021 gcgcggaggt agtcgggaaa ggcgtcgcgc gggggtacgt cgggacgccg ggaccagcgg
     1081 tcgagcaccg gctcgtgggc gtcgaggaag gtgcggtgga gcttcgcgat ggcgtcgagg
     1141 tcccaccagc ggcggacggc ggtggcggtc ggttcgaagc cgaggtgcgt gccgtggaag
     1201 aggtccacgt aggagtcgag ttcgaggcgg cgcagggtgt ggcgggcctc ctcctggacg
     1261 tgggccgggg ctatccagac gccgggcgcc gcgctgccga agccgagccg ggccagccgg
     1321 gagcgcagca gatggcgctt gtggcgctcg gtctcgggga cggagaagac ggcgagcacc
     1381 caggagccgt cgccgtcgct gttgccgtcg ccttcggcag agccggggcc gccgtagatg
     1441 cggcggtcgc cgtcggcgag gagctggcgg gcgtcgtcgg agagcgcgta cgcggcggcg
     1501 ccgccgacac ggtccgggac cagcagctcg cgccgcttga gccgggagac ggccgagcgg
     1561 accgactgcg ggtcgacgtc caccgcgccc atcagccgga tgagggcggc gaccggtacc
     1621 cggccgtcca gttcggcgcg cccgtaggcg ccgaagaagg tcacgatcag cgaactgggg
     1681 gtgtgctcgg tcacatgatc actctaggtc gcgcagccgg aagcgctgca gtttcccggt
     1741 gggagtgcgg gggagggcgt ccaggaagac gatgtcgcgc gggcacttgt agggcacgat
     1801 cacgcccttg gcgaagtcgc gcagcgcccc caccgtggcc gtgccgcgcg gtacgccgtc
     1861 gcgcaggacg acgaaggcgc ggacgatctg gccgcgctcc tcgtccggga cgccgatgac
     1921 ggccgcctca ctgacgtcgg ggtgccgcag cagcgcctcc tcgacctccg ggcccgcgat
     1981 gttgtagccc gccgagatga tcatgtcgtc ggcgcgggcc acatagcgga agtagccgtc
     2041 gggttcacgg acataggtgt ctcccgtgag gttccagccg ccctgcacgt acacggtctg
     2101 acgctcgtcg gcgaggtagc ggcagcccgt cgggccgcgc accgcgagca gccccggctc
     2161 gccgtcgggg accggctccc cggcggcgtc gacgatccgc gcccggtagc cgggcaccgg
     2221 caggcccgtg gtgccggggc ggatggcgtc gtcggcggcg gagatgaaga tgtgcagcag
     2281 ctcggtggcg ccgatgccgt tgatgatgcg cagaccggtg cggtcgtgcc acgcctgcca
     2341 ggtggccgcg ggcagattct cacccgccga aacgcagcgc cgcagcgacg agacatcgta
     2401 cgaggcggag ctgcttgcgt cattcaggtg accgagcatc gcccggtacg ccgtcggcgc
     2461 cgtgaacagc acgctcaccc ggtgccgggc gacggccgcc agcaactgct ccggtccggc
     2521 ctgctccagc agcacgctgg acgccccggc ccgcatcggg aagatcacca gcccgccgag
     2581 gccgaaggtg aagccgagcg gcgggctgcc cgcgaagacg tcgtcggcgc gtgggcacag
     2641 cacctgggcg gagaacgtgt cggcgatggc caggacgtcg cggtggaagt gcatacagcc
     2701 cttggggcgg ccggtggtcc ccgaggtgaa ggcgatgagc gcgacatcgt cggacgaggt
     2761 ggcgacgtcg gtgaagtggt cgggcttgtc ggcggcccgg cgcaacaggt cctcgggcgc
     2821 ctctccgccg tacgtggtga tccgcaggtc cgggatctcg gccttggcca ggtcgtccac
     2881 cgaccgcaga tcgcacagcg cgtgccggac ggccgcgatg tcgcagatcg tcgcgagctc
     2941 ccctgaacgc tgcgcggcca gtacggtcac ggccaccgca cccgccttga gcaccgcgaa
     3001 ccagcaggcc accagccacg gggtggtcgg gccgcgcagc aggacccggt tgccgggccg
     3061 caccccgagg tcgtcggcca ggacgtgcgc gatacgcgcg gcggtggcgt tcaggtcctc
     3121 gtaggaccag acctcgccgc cgggggtgcg cagacagggg gcgccggggc tgccgccggc
     3181 cagcagctcg gccgcgcagt tgagccggtc ggggtagtgc agcgcgggca gctcgaaggc
     3241 gagttccggc cactggtcgc gcggcgggag atggtcccgc gcgaaggtgt ccacgtgggc
     3301 ggatggcagc aggtccatgg cggtaccgcc ttcgttggca cctgagagcg gacgaattca
     3361 gcgtaacgtg ttgctgacga cagtcaacgg tacgcgatac cgcttggagg cgccggatgc
     3421 ccgcgttcgc tctcgacccg gaacagctga agtggtgcgc cgaggtccgt tccctcgcgg
     3481 cgggccggct gcggccgctg gccgaggcgg gcgaacccgg ccgggtcaac cgcccgttgc
     3541 tcgcggaact gggcgaactc gggctgctgg aacgggtctt cccgcccggc ggcaaggtgt
     3601 cggcgatgga cctgtgcctg ctgcgggaat cgctggcccg tgagtgcacc gaggccgaga
     3661 cggccctcgc cctgcaggga ctgggcgcgc acccggtgct gcacaacgcc gagctggccg
     3721 cccgctggat cccggaggtc acggcgggcc gggccgtcgc cgccttcgcg ctcaccgaac
     3781 ccgccgccgg ctccgacgcg gcggcgctgg agctggccgc cgagccggac ggcacgggat
     3841 ggcggctgac cggcgagaag tgctggatct ccaacgctcc gcaggccgac ttctacacgg
     3901 tcttcgcccg caccacaccc ggcgcggggt cgcgcggggt gacggcgttc ctcgtccccg
     3961 ccggccggcc ggggctgtcc ggtgagcatc tggacatgct ctccccgcac cccatcgggc
     4021 ggctcgcctt cgacggcgtc ccggtcggcc ccggcgatct gctgggcgag ccgggccggg
     4081 gcttccgggt cgccatgggc accctgaacc tgttccggcc cagcgtcggg gcgttcgccg
     4141 tcggcatggc gcaggccgcg ctcgacgccg ccaccgagca cgcgggcgga cgcaccgcct
     4201 tcggcgggcc gctgaaggat ctgcaggcgg tgtcccacgc gctggcggag accgcgaccc
     4261 gcacggaggc cgcacggttg ctcgtctacg ccgcggcgga ggcgtacgac agcggggcgc
     4321 cggatatcgc caagcggtcg gcgatggcga agctgtacgc gaccgagacg gcgcagttcg
     4381 ccgtggaccg cgcggtccag atccatggcg cccgcgccct cgaacgcggc catctgctcg
     4441 aacacctcta ccgtgaagtg cgggcgccgc gtatctacga aggtgccacc gaggtccagc
     4501 gcaccatcat cgcgaaggag ctgtaccgat gagcctgcgg cgcatcaacc cgggcgagct
     4561 gtcgccgccc accggcttca gccacgccgt caccgcgacc ggccgcacga tggtcttcct
     4621 ggccggccag accgccctcg accaggcggg caagatcgtc ggcgacacgc tgcccgccca
     4681 gttcgagctg gcgctcacca atctgctggc ggcgctggcc gcagcgggcg gcggccccgc
     4741 cgacctcgcc cggatcaccg tccacaccac cgacgtcgcc gcctaccggg agcacgccgc
     4801 cgaactcggg cggttgtggc ggtcgttggc gggccgcgac tatccggcga tggcggtcgt
     4861 cggggtggtc cggctgtggg acgaggaagc gctggtggaa ctcgacggga tcgccgtcct
     4921 ggcgtagcgc gggaagcgtg cgcggacggg atcccgcggc gtcccttggc accgcgtaag
     4981 ccatgtgaca tattactgcc gtgctcacga gacactcgct ggacgtcgtc atcgtcgggg
     5041 ccggggtggt cggcgcggcc tgcgcctact acgcctcccg gtccggactg tccgtcgccg
     5101 tggtcgaccg cggctccgtc gcgggcggca ccacgggcgc cggtgaaggc aatctgctgg
     5161 tctccgacaa ggagcccggc cctgaactcg accttgcgct gctgtccacc aggctctggc
     5221 gcgagctcgc cgacgaactc ccaccggaga tcgagttcga gtccaagggc ggcctcgtcg
     5281 tagcgtccga cgaggcccgc ctggacgccc tgagcacgtt cgcggcccag cagacggcag
     5341 cgggtgtcac cgcggcccgg gtgccggcgg accggctgca cgagttcgaa ccgcatctgg
     5401 cgcccggcct cgccggcgcc ttccactacc cgcaggacgc ccaggtccag cccgccctgg
     5461 ccgccgccca tctgctgcgc gccgcccggc gcgccggcgc gctgctgtgt ctcggcgaag
     5521 aggtcaccgc cgtcctgacc ggccctggcg gcgcggtccg cggggtgcgc accgaccgcg
     5581 gtgaactgtc ggcacccgcc gtggtcaacg cggccggcac ctggggcggc gaactcgccg
     5641 cgttggccgg ggtggacctg ccggtcatgc cccggcgcgg cttcgtcctc gtcacggaac
     5701 cgctgccccg catcgtccgg cacaaggtct acgccgccga ctacttcgcc gatgtggcga
     5761 gcggctccgc ggccctgcag acgtcaccgg tggtcgaggg caccccctcg ggaccggtgc
     5821 tcatcggcgc cagccgggag cgggtgggct tcgaccggac gctgcgggtc gaggtgctgc
     5881 gccggctcgc ggccggggcc gccgggctct tcccggtgct ggccggggtc cgggtgatgc
     5941 gcgcctatca cggcttccgg ccctatctgc cggaccatct gcccgcgatc gggcccgacc
     6001 cgcgcgcccc cggcctcttc cacgcctgtg gccacgaggg cgcaggcatc ggactcgcgc
     6061 ccgcgaccgg actgctgctc accgccgcga tccggggcca gcggcccgcc ctggacctgg
     6121 caccgttccg ccccgaccgc ttttcccgcc gcggacccga ttcccggcgg ggaaccgggc
     6181 ggacccgcgg acccgagagg acatgacgat ggcgcgtaac cccgtcgagc tggccggggc
     6241 cacccccgag ccgtcgttcg agatcacgat ggacggccgc gtcctgcccg cgctgccggg
     6301 ccagagcatc gccgccgccc tgtggtcggc cggcatcctc gcctggcgta ccacccgggt
     6361 gaacggccgc ccgcgcggcg ccttctgcgg catcggctcc tgcttcgact gcctcgccac
     6421 cgtcaacggc gccccgaacc agcgggcctg cctggtcccg gcccgtccgg gcgatctcgt
     6481 caccacgcag gagggccacg gccgtgccga tctcgccgtc tgagccgccg gtacctccgg
     6541 agtacgacct cgcgatcgtg ggcgcgggcc ccgccgggct ctcggccgcc gtggccgcgg
     6601 ccgatctcgg gctgagcgtc gtcgtgctcg acgcggccgc cgcccccggc ggtcagtact
     6661 accgccatcc cgcgccggga ctcggcgccg cgcgccccga ggcgctgcac cacggctggg
     6721 ccgccttcgc cgcgctggtg cgacggctcg gccggcacac cgggaccggc aaggtccggc
     6781 acctgaccca ccaccatgtg tggacggtgg aacgcggcag ttcgacggcg tggacggtgc
     6841 atgccgtgac cggtcctgac gggccggagc agggccgggc ggccgtgacg tcacgcgcac
     6901 tgctgctggc caccggctcc tacgagcgcc aactgccgtt ccccggctgg acgctgcccg
     6961 gggtggtcgg tgcgggtggc gcccaggcga tgctcaagtc cggcctggtg ctgcccggac
     7021 ggcggatcgt cgtcgcgggc agcggcccgc tgctgctggc ggtcgccggc tcgctggccg
     7081 ccgcgggcgc gaaggtgccc gccgtcgtcg aggcggccgg gtacaccgcg tacgccggaa
     7141 gcccccggac gctggccgcc aaccccggca agctgctcga aggcgcggtg cacggcgccg
     7201 ccctgctgcg ccacggcctg cgcccgcgca cccgcagcgc ggtgaccgag gctcacggca
     7261 ccgaccgggt ggaggccgtc accgtctccc ggctggaccg cgactggcgt cccgtgccgg
     7321 gcaccggccg ccgcatcgcc tgcgacgcgc tcgcggtggg ccacggtctg gtgccgcagc
     7381 tggagctggc caccggactc ggctgcgcca cccaccgcac ccccgacggc acgtacgcgc
     7441 tcgctctcga cgacagccag cggacctcgg tgcccggcgt ctgggcggcc ggcgaggccg
     7501 gaggagtggg cggcgcccaa ctcgccctcg ccgaggggga actggcggcc ttcgccatcg
     7561 cggccgtgtc gcgttccgcg gtacgccccg acgcccggcg ggcggtcgcg ctgcgccgta
     7621 cccgagcccg gctgcgggcc ttcgcggcgg tcatggccgc cgcccaccgg ccgggccccg
     7681 gctggccgga ctggctgagc gacgacaccg atgtgtgccg ttgcgaggag gtctccgcag
     7741 gggaggtccg cgcggcggtc accgatctcg gcgcccatga cgcccgcacc gtcaagctgt
     7801 tcacccgcgc cgggatgggt tggtgccagg gccggatgtg cggcccggcg gtcgactgcc
     7861 tggcgcgcgc cgactcgcac gcagacgcag acgcagatgc ggacgcagac gcagatgcgg
     7921 acgccggccc cgaccgccga ccgctgtcgt gtcccgttcc gctggccgcc ctgtcccgac
     7981 cggcggctct gtccggtccg gacgggccgc cccgctcgtg agcacggaag aaccgtagga
     8041 ctctcctcgg tgagcctctt gtggtctccg tccacgacac agtaaaatgt cacatctcac
     8101 taagggagaa ccaccgtgac cacgaacacc ccgccccgcg accagccctg gcacggcatc
     8161 atggtcgcca ccgccctccc gttccatgcc gacctgcgcg tggaccacga cggttacgcc
     8221 gagcacgtcg cctggctcat cgagtccggc tgcgacggtg tcgttcccaa cggctccctg
     8281 ggggagtacc agaccctgac cgacgacgag cgggcccggg tcgtccgtac cgccgtcgag
     8341 gcggccggtg acggggaccg cgtcatgccc ggtgtcgccg cctacggcag cgacgaggcc
     8401 cgccgctggg ccgaacaggc cggagaggcc ggtgccggct ccgtcctgct gctgccgccc
     8461 aacgcctacc gcgccgacga gcgggcggtg cgcgcgcact acgccgaggt ggccagggcc
     8521 gggctgccgg tcgtcgcgta caacaacccg tacgacacca aggtcgacct cactccgcag
     8581 ctgctcgccg agctctacaa cgagggcagc atcgtcgcgg tcaaggagtt caccggcgat
     8641 gtccgccggg cctacgagat cgccgaactc gcccccggac tggatctgtt ggtcggggcc
     8701 gacgacgtcc tgctcgaact cggcatcgcg ggcgccgtgg gctggatcgc gggctacccc
     8761 aacgcgttcc ccgaggcctg cgccaccctg taccgggcgg cgctctccgg cgacctcgac
     8821 accgccgtgc cgctctaccg cgcgctgcac ccgctgctgc gctgggactc caagcccgag
     8881 ttcgtccagg ccatcaaggt gtccatggac ctcgtgggcc ggcccggcgg cccggtccgt
     8941 ccgccgcgct ccccgctccc ggccgacatc gaggccgtgg tccgcgccgc gaccgagaag
     9001 gcgatggccg aaggactcgg ctgacccacg agcaggccga cgggctggcc gacgggctgg
     9061 ccaacgagct ggccaatgag ccagtcaacg agaactccga cgagaaggag gaccccttgc
     9121 gcagccggaa catctaccac gccgtcgact cgcacaccga aggcatgccg acccgcgtca
     9181 tcaccggcgg cgtgggcgtc atccccggcg ccacgatggc cgagcgccgg ctgtacttca
     9241 tggagcacca cgaccgggtg cgcacgctgc tgatgtacga gccgcgcggg cactcgtcga
     9301 tgagcggcgc gatcctgcag ccgccgacgc ggcccgacgc ggactacggg gtgctgtaca
     9361 tcgaggtctc cggctacctc ccgatgtgcg gccacggcac catcggcgtc gccaccgtcc
     9421 tcgtcgagac cgggatggtg ccggtcaccg aaccggtcac caccgtccgg ctggacaccc
     9481 ccgccgggct cgtcaccgtc gacgtccagg tcgaggacgg ggaggccacc gccgtcaccc
     9541 tccggaacgt cccggcgttc tccgccggcc tggacctcaa ggtcgacgtc cccggccacg
     9601 ggacgctcac ctacgacctc gcctacgggg gcaacttcta cgcgatgctg ccgctggccg
     9661 acctcgggct gcccttcgac cgggagcgca agaacgacat cctcgccgcc gggctcgccg
     9721 tcatggaggc catcaacgcg gcggaccggc cggtgcaccc ggaggacccg gacatcaacg
     9781 gggtcaagca cgtccagctg atcgcccccg gctccgacgc gcggctgtcc cggcacgcga
     9841 tggccatcca ccccggctgg ttcgaccgct cgccgtgcgg caccggcacc tcggcgcgga
     9901 tggcgcagct gcacgcgcgt ggtgaactcc cgctgcacac cgacttcgtc aacgagtcct
     9961 tcatcggaac gttcttcacc ggccggctcg tcgaggagac cacggtcggc gggctgcccg
    10021 ccgtggtgcc cacggtcacc ggccgcgcct ggatcaccgg caccgcccag tacttcctcg
    10081 acccgtccga ccccttcccc ggcgggttcc tgctgtgatc accgacggcg ggtacggtcg
    10141 ggaggaaggg gctcaccggg ccgcggtgcc gccctccgac gaccttccgg gaacgggacc
    10201 accgctgtga cactgccgca cctcgacgcc accgccatcg cccggctcct cgggcccgcc
    10261 gacgcggcgg acgccgtcga agcggtgctg cgcggcgggc tcgacccgga gaccgggccg
    10321 ccgcgcaccg gcgtcccggt cccggccggc gagttgctgc tgatgcccgc cgccacgaag
    10381 gacttcgctg gagtgaagat cgccggggtg gcgccgggca acccggcccg cgggctgccc
    10441 cggatcaccg gcagctacct cctcctcgac ggcgcgaccc tccagccggt cgcgctgctc
    10501 gacgggcccg ccctcacctc gctgcgcacc ccggcggtgt ccgccgtcgc gatccgccac
    10561 ctggccgtgc ccgacgcctc gcacctcgtc ctgttcggag cgggaccgca ggcgtacggg
    10621 cacctggcgg cggccctcgc ggtccggccg ctgacccggc tcaccgtggt cgcccgcagg
    10681 cccgagcccg cgcaggcgct ggtggcccac gcccgccggc tcggactgga cgccgtgacc
    10741 ggcggacccg acgcggtggc caaggccgac ctggtgatct gctgcaccac ggcccgcact
    10801 ccgctgttcg acggcagcac cgtcgccggg cacacgaccg tggtcgccgt cggctcgcac
    10861 gaagcgtcgg cccgcgagac cgacaccgcg ctggtgaccc gggccaccgt cgtcgtcgag
    10921 gcgcggtcgg ccgcgctgcg cgaggcgggg gacatcctgg tcccgatcgc ggagggcgcc
    10981 taccggccgg aggatctcgc gggcaccctc gccgacctcg tcgccggccg gctgcgccct
    11041 gaagcgggcc gcccgcgctt cttcaagggc acgggtatgg cgtggcagga tctcgccgta
    11101 gctgctgaga tcttccgggc cgcgaaagca acgtgacatt gtacgctgga gctccgcgcg
    11161 atgacggagg aacagcgatg ggtgacctga agcagcgcaa cctgatcaca gcgcaggagc
    11221 ggctgcgcga tcaggtgggc cacgccctgc gtgccgcgct catcgccggt gaactgcgcc
    11281 ccggcgtggt ctactcggcg cccgccctcg ccgcggactt cggcatctcc gccaccccgg
    11341 tgcgtgaggc gatgctcgac ctggcgcgcg agggcctggt cgaaccggtg cgcaacaagg
    11401 gcttccgggt caccgagatg aacgagcgcg acctcgacca gtacaccgag atccgcgccc
    11461 tcatcgaggt cccgaccgtc ggccgggtca cccgcaccgc caccccggaa cagctggagg
    11521 aactgcggcc ggccgccgag gagatcgtcg ccgccgcccg ggcgcacgac ctcatcggct
    11581 atctggaggc cgaccgccgt ttccacctca ccctcctcgg cctggccggg aacgagcggc
    11641 tggtcgaggc cgtcggcgat ctccgcaagc gctcccggct gtacgggctg acgcggctgg
    11701 acgagcgcgg cgagctggtc tcgtcggccg aggagcacat cgagctgctc gacctgatga
    11761 ttttcgggga cgcggaggcc gcggaggagt gcatggcccg gcacctcggg catgtgcggt
    11821 cgctgtgggc ggtgggcaag gaggagccgg ccgcggcgaa gccggagccg gtcctcaagc
    11881 gcaagctcgg caaggcttag gccggttgcc ctgcggggcg agggcgaaag ccccgcaggg
    11941 cgcccccgct aaccgagcag ctcgcccatc cagctctcga tccccgcgac atcgcgcggc
    12001 agtgcccccg acatcaggcg ggccccgtcg gacgtgatga ccaggtcgtc ctcgatccgg
    12061 atgccgatgc cgcgcagttc cagcggcagc gtctcgtcgt cgggctggag gtacaggccc
    12121 ggttcgacgg tgaggacatg gccctcctcc agtaccgcgt cgaggtaggt ctcggcgcgg
    12181 gcctgggcgc agtcgtgcac gtcgaggccg agcatgtggc cgctgttgca cagcgtgtag
    12241 cggcggtaga ggccgctgtc ctcggcgagc gcctcgtcgg cggagatccg cagcacgccc
    12301 cagtcggcga gcccttcggc gatgacgcgc atgcccgcga ggtggaagtc ccggaagctg
    12361 gcgccgggtt tgagggccgc gataccggcg tcctgggccg ccaggaccag ttcgtacagc
    12421 tggcgctgga cgggggagaa gatgccggac agcggcagcg tgcgggtgac gtcggcggtg
    12481 tagagggtgt cggcctccac gcccgcgtcg agcagcagca gttgcgtggg gtccagcgcg
    12541 ccgtcgttgc gtatccagtg cagtacgcag gcgtgcgcgc cggacgcggc gatggtgttg
    12601 tacccggtgc cgttgccctc ggcgcgggcg cgctggttga acgccccctc gatccagcgt
    12661 tcgccgcgcg cgtgccgcag ggcgcgcggc agggaccgta cggcgtcctc gaagccggcg
    12721 accgtgtggt cgacggcgag ttgcagctgg ccgacctccc acgcgtcctt caccagccgc
    12781 aactccgaga gcgcactggc gagttcggtg tccgtcgtgg cgtcgcggcc cggcggcagt
    12841 gcgccgaacc cgtcgaggtg ctcgcaccgg atgccggtca tccgctcggc ttccgcgagg
    12901 tcggggcggc gcccgaccca gaactccccg tagcggcggt cgcggtagaa cccggcctcg
    12961 gtgcgcggtg agcgcggccg cagatacagc acggcctcgt gcccggaggg accggacggc
    13021 t
//
