LOCUS       NZ_CP048835            32712 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6934206
            Orig. end                         :: 6966918
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..32712
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="16"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..32712
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32712
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:18712](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..18712
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    310..321
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(978..988)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            1401..2123
                     /locus_tag="C8250_RS31045"
                     /old_locus_tag="C8250_031060"
     CDS             1401..2123
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520784.1"
                     /locus_tag="C8250_RS31045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031060"
                     /product="class III extradiol dioxygenase subunit B-like
                     domain-containing protein"
                     /protein_id="WP_138357317.1"
                     /transl_table=11
                     /translation="MLVAAAVCPSAPLLVPEVAAGAAFELDALRAACADAVGVLAASRP
                     DRLVVIGPAGQPDRGRHHEGARGSFREFGVDLDVRLGTAPGTPSEDVGADRALPPSLAV
                     AAWLLRGWAAAPLEGLGVGEPLEQDRCAATGAMIASTADRVALLVMGDGSACRTLKAPG
                     YLDERAAPFDASVAAALAAADTEALAALDAELAETLQAAGRAPWQVLAGAAQGAGLAGQ
                     LLYEDAPYGVGYFVATWT"
     gene            complement(2246..2485)
                     /locus_tag="C8250_RS31050"
                     /old_locus_tag="C8250_031065"
     CDS             complement(2246..2485)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128045.1"
                     /locus_tag="C8250_RS31050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031065"
                     /product="antitoxin"
                     /protein_id="WP_138357316.1"
                     /transl_table=11
                     /translation="MGLMDTIKDRLGLARNKAGDLAQQHGGKIESGLEKAARTVDSRTH
                     GKYTDKIDTGVHKAKGALDHLKSGKEGSGPDTPA"
     gene            complement(2508..2744)
                     /locus_tag="C8250_RS31055"
                     /old_locus_tag="C8250_031070"
     CDS             complement(2508..2744)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060983.1"
                     /locus_tag="C8250_RS31055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031070"
                     /product="hypothetical protein"
                     /protein_id="WP_138357315.1"
                     /transl_table=11
                     /translation="MGVFGWFRRQSADPSTEAAEAVTLTAEPEGVEAVAEPAEAAEPAG
                     DAEPAGAAEPVGIPKQQSTADAADSEAGEGARA"
     gene            2940..3890
                     /gene="miaA"
                     /locus_tag="C8250_RS31060"
                     /old_locus_tag="C8250_031075"
     CDS             2940..3890
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382842.1"
                     /locus_tag="C8250_RS31060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031075"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_138357322.1"
                     /sec_met_domain="IPPT (E-value: 2.5e-81, bitscore: 271.9,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTPGERPPVLPSKDLVIAVVGPTAAGKSDLGVALAQALNGEVVN
                     ADSMQLYRGMDIGTAKLTTDERHGVPHHLLDIWDVTEAASVAEYQRLARAEIDRLHAAG
                     RTPVLVGGSGLYVRGAIDALEFPGTDAAVRARLEAELAEQGSAALHARLAAVDPEAGRA
                     ILPSNGRRIVRALEVVEITGRPFTANLPGPDSIYGTVQIGVDVPRPELDERIALRVDRM
                     WDAGLVDEVRELAAVGLRDGRTASRALGYQQVLASLVGECTDDEARAETVRATKRFARR
                     QDSWFRRDQRVHWLSARGPELTDQALTLVEAAVTA"
     gene            3996..4454
                     /locus_tag="C8250_RS31065"
                     /old_locus_tag="C8250_031080"
     CDS             3996..4454
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561822.1"
                     /locus_tag="C8250_RS31065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031080"
                     /product="hypothetical protein"
                     /protein_id="WP_138357321.1"
                     /transl_table=11
                     /translation="MEAGPRDSSPDRHAETEAQLGTDELLEPGSLIDPEAMIEPELVPV
                     ELRPQRRLRIWQLAPIVALGVGGSLMFAFPLAFEFGDGGAVVAMLGLLLSCCSAGWGIM
                     AARRVGYTWPGLPARGSGRRADWRFIVAYTLISGLLAVLAIWRVARLR"
     gene            4515..5423
                     /gene="dapF"
                     /locus_tag="C8250_RS31070"
                     /old_locus_tag="C8250_031085"
     CDS             4515..5423
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175919.1"
                     /locus_tag="C8250_RS31070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031085"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_138357314.1"
                     /transl_table=11
                     /translation="MTTTQPTTHQGLSFLKGHGTENDFVIVPDADGRIELSAAAVARLC
                     DRRAGIGGDGLLRVVRSEAHPEAAGMAGEAEWFMDYRNSDGSIAEMCGNGVRVFARYLQ
                     RAGLTGPGDLAVATRAGVRRVHIAKTDADGTLGGITVGMGAAALPAGEVTVTVDGRSWL
                     ASNVNMGNPHAVAFVGSLDDAGNLYTAPTVTPAAAYPTGVNVEFVVDRGERHVAMRVHE
                     RGSGETRSCGTGACAVMVAAARRDGADPAITGRPVTYTVDVPGGRLVITERADGEIEMT
                     GPAVIVAEGTIDREWLDAPSA"
     gene            5654..7831
                     /locus_tag="C8250_RS31075"
                     /old_locus_tag="C8250_031090"
     CDS             5654..7831
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055359.1"
                     /locus_tag="C8250_RS31075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031090"
                     /product="HD domain-containing protein"
                     /protein_id="WP_138357313.1"
                     /transl_table=11
                     /translation="MSADNAVDAAPAPDDEGRRRGLRRIDLRRLGRAALLGPGGREWGL
                     PAGGRGQRVPDAIEHLAKVHRLRHPGVGAAGIETLRRAYLLAESSHRGQMRKSGEPYIT
                     HPLAVTLILAELGAETTTLTASLLHDTVEDTEVTLDQVREEFGEEVCYLVDGVTKLERV
                     DYGAAAEPETFRKMLVATGSDVRVMSIKLADRLHNMRTLGVMRPDKQARIAKVTRDVLI
                     PLAERLGVQALKSELEDLVFAILHPEEYARTRAMIRANSVRPDPLAAVADAVRAVLREA
                     GIAAEVAIRPRHTVSVHRVLLKRGADELGGCEFGRILVLVAEDADCYAVLGELHTCFIP
                     VIAEFKDFIAAPKFNLYQSLHTAVADEEGRIAEVLVRTRQMHRVAEAGVIALGNPHTVD
                     EPPQAADGERVDPTQPGWLSRLLEWQRDAPDPDTFWTALRADLAQDREVTVFSAHGGDT
                     TGTIRLPAGASCVDAAYALHGEAGHACVGARVNGRLAPLRSKLRDGDIVQILLDETGAS
                     GPSADWLEHVRTPAARIAVTRWLELHPVPPADEEPAARAERPAYSADTAAEDEPVAVTD
                     LAGAAVRLARCCTPVPPDEVTGFVIRGGTVAVHREECPTAVRMIGAGREPVPVRWRGGR
                     PAGAGFRATLLAEALGRPRLLADLTEAIAGQGVGIVSASVEPPQEHRVRHTYTVELPDA
                     EALPSLMRAMRSVPGVYDVYRAQRAMAAARR"
     gene            7982..9454
                     /locus_tag="C8250_RS31080"
                     /old_locus_tag="C8250_031095"
     CDS             7982..9454
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034839.1"
                     /locus_tag="C8250_RS31080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031095"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_138357312.1"
                     /transl_table=11
                     /translation="MIPITPRSGAVLAAFAAVLTLTAADLPGDPAVSTSGLGDRLYPDL
                     GNPGYDVAAYDLSFDYHGQDRPLDAVTRIKARATAPLTGFHLDFAAGTVSSVQVNGHPA
                     VYTREREELVVTPEEPVPDGGELLIAVTHTSDPRAANTGWVRTADGLAMANQADAAHSV
                     FPCNDHPSDKAAFTFHVTAPKDLTVITNGVPDAVPEAAPASALTWTYRPASPMATELAQ
                     VSIGRSAVLHRAGPHGLVLRDVVGAADRDRLEARLAMTPGQISWMEEQVGPYPFETYGI
                     LSADTTTGFELETQTLSLFERRVLLAPEALAAPLMVHELAHQWFGDSVTPAAWSDLWLN
                     EGHATWYQWLYNAQKYGVGLDQQVRAAYEGDNRVRAADGPPAEPKVPEPGKLGIFRNNV
                     YDGGALALYALRQEIGAPAFQRLERAWVARHQDGNASTADFTALASEVAERDLSGFLHA
                     WLYGTVTPPMPGHGDWVAGAARARAATAAKPA"
     gene            9535..11040
                     /gene="hflX"
                     /locus_tag="C8250_RS31085"
                     /old_locus_tag="C8250_031100"
     CDS             9535..11040
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="hflX"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018535926.1"
                     /locus_tag="C8250_RS31085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031100"
                     /product="GTPase HflX"
                     /protein_id="WP_138357311.1"
                     /transl_table=11
                     /translation="MTSSSSSSNDRQRLPESLRADALMEEDVAWSHEIDEERDGAQLER
                     SDRASLRRVVGLSTELEDVTEVEYRQLRLERVVLVGVWTSGTVHDAENSLAELAALAET
                     AGALVLDGVIQRRDKPDPATYIGSGKARELRDIVQETGADTVVCDGELSPGQLIQLEDV
                     VKVKVVDRTALILDIFAQHAKSREGKAQVSLAQMQYMLPRLRGWGASLSRQMGGGGSSG
                     GGAGGGGGMATRGPGETKIETDRRRIREKMAKMRREIAEMKTGRDLKRQERKRNKVPSV
                     AIAGYTNAGKSSLLNRLTGAGVLVENTLFATLDPTVRRAETPGGRLYTLTDTVGFVRHL
                     PHHLVEAFRSTMEEVAEADLILHVVDGSHPVPEEQLAAVRDVFREVEALKVREIVVINK
                     ADLADPLVLQRMLRNEKHAIAVSARTGQGIDELLALLDEELPRPEVEVDVLVPYSQGAL
                     IARAHADGEVLSEEHTGEGTLLKARVHEDLAAEFASFALVAKH"
     gene            complement(11127..12290)
                     /locus_tag="C8250_RS31090"
                     /old_locus_tag="C8250_031105"
     CDS             complement(11127..12290)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742942.1"
                     /locus_tag="C8250_RS31090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031105"
                     /product="hypothetical protein"
                     /protein_id="WP_138357310.1"
                     /transl_table=11
                     /translation="MPSISRPLAAAAVAALLAVSATACGPSDDKADPKPSAPVTSADGP
                     KLPSALPTSLGDLEKWKKAYKDGAWKNWDKDQWLRKASDFINPVIDGLWDNDRMKGAEQ
                     NDKKVPDDVAADKGKTDAVPAVNKAKAVDAPYHENGPGDGKIFFDGPKGSMVCSGTVVQ
                     DPAHPGKSNLVWTAGHCVHAGGAGGWYRNVIFVPSYNDAGRTEAQLKGAKRDELAPLGV
                     FWADGAATSDQWIANGAETGGKGSPYDFAVLHVTPDKASGTKSLEEKVGSALPVWFNAP
                     SVTKMGNIGAWGYPAAPPFDGQRLFNCTGKAGRLSLFADQPTEYRLGCTMTGGSSGGGW
                     YAKNPANNQVSLVSNTSIGPVTATWLAGPHLGAEAKAVYDKVSKQFK"
     gene            12454..14004
                     /locus_tag="C8250_RS31095"
                     /old_locus_tag="C8250_031110"
     CDS             12454..14004
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (56-398). E-value: 2.9e-88.
                     Score: 288.0. Matches aSDomain:
                     nrpspksdomains_C8250_RS31095_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003983928.1"
                     /locus_tag="C8250_RS31095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031110"
                     /product="diaminobutyrate--2-oxoglutarate transaminase
                     family protein"
                     /protein_id="WP_138357309.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.5e-89, bitscore:
                     297.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDVDRRSEHVAAIQSGPDQLAASADDFVAGEGILRRQSLRESAA
                     RTYARSLPVVPVRARGMTVEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRAVLDSGAP
                     LHVLDLATPVKDAFTTALFETLPPELAAHGRVQFCGPAGTDAVEAAIKLVRNATGHAGL
                     LAFTGAYHGMTAAALAATGDTAARATVGEADARVTRLPYPYEYRCPFGTGGDRGAELSA
                     RWTASLLDDPKGGVQPPAGMLLEVVQGEGGVIPAPEAWLRRMREITARRGIPLIVDEVQ
                     TGVGRTGTFWAVEQSGIVPDVMVLSKAIGGSLPLAVIVYREELDTWRPGAHAGTFRGNQ
                     LAMAAGAVTLKYVREHGLDVRAGTLGSRMSARLRGLAAHHPCIGDVRGRGLMIGLELVD
                     TEAEPDDYGSLPAAPRLAAAVQQEALRRGLIIELGGRHSSVVRLLPPLTITDEQAEAVL
                     DRLADSIAAAERAVSGAPGAPGAPGTSGGSGTAGTPGARVGPGFSGASAGAGAVEERA"
     aSDomain        12622..13647
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS31095_Aminotran_3.1"
                     /evalue="2.90E-88"
                     /label="C8250_RS31095_Aminotran_3.1"
                     /locus_tag="C8250_RS31095"
                     /protein_end="398"
                     /protein_start="56"
                     /score="288.0"
                     /tool="antismash"
                     /translation="VRARGMTVEGADGRRYLDCLSGAGTLALGHNHPVVLEAIRAVLDS
                     GAPLHVLDLATPVKDAFTTALFETLPPELAAHGRVQFCGPAGTDAVEAAIKLVRNATGH
                     AGLLAFTGAYHGMTAAALAATGDTAARATVGEADARVTRLPYPYEYRCPFGTGGDRGAE
                     LSARWTASLLDDPKGGVQPPAGMLLEVVQGEGGVIPAPEAWLRRMREITARRGIPLIVD
                     EVQTGVGRTGTFWAVEQSGIVPDVMVLSKAIGGSLPLAVIVYREELDTWRPGAHAGTFR
                     GNQLAMAAGAVTLKYVREHGLDVRAGTLGSRMSARLRGLAAHHPCIGDVRGRGLMIGLE
                     LV"
     gene            14001..15998
                     /locus_tag="C8250_RS31100"
                     /old_locus_tag="C8250_031115"
     CDS             14001..15998
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564693.1"
                     /locus_tag="C8250_RS31100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031115"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_244809467.1"
                     /sec_met_domain="IucA_IucC (E-value: 3.2e-73, bitscore:
                     245.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPQATAEYPQTSGPTGPTDTRSTGMSVCPGTNADPAADSTPAQ
                     AGAAQQDRPTLHGGPAHQTGTAVQDSTALVPPQSRRAALPLPGEPDPLEASDAYAAADA
                     ASIESLLRCWVRETALPEPRDGVLRVPLPASGTGFDVRVRHWSATGHHRFGTVRLALAD
                     QVPLTAVCLAALLAREAGTDPAEGGDLIGRVADSARRTALFLTDRRERPAAPAATDPFL
                     EAEQSLLLGHPLHPTPKGREGLSEAESRAYSPELRGSFPLHWFAVDRSLIATDSAWTER
                     GRAIPAEQLLTDLAGPGLELPDGAAALPLHPWQAREVQHRPEVRELFETGQLRDLGPLG
                     DPWHPTSSVRTVYRSGAPALLKLSLALRITNSRRENLRKELRRGTEVHRLLRSGLAEQW
                     RAAHPGFDIVRDPAWLAVNAPGGEPLQGLDVVLRHNPFGPGDQTHCLAGLTSPRPWPGQ
                     AAPALRSRLADLTGRLAARTGRPAAAVATEWFLRYLDAVVRPVLWLDGEAGIALEAHQQ
                     NTLVLLDADGWPSGGRYRDNQGYYFRESHRAALERRLPGIGAESDTFVADAIADERFAY
                     YLGINNVLGLIGAFGSQGLADERLLLAAFRRFLGLAAATGRSRLPEQLLGAATLRCKAN
                     LLTRLHGMDELVGPVDTQSVYVTIRNPLAA"
     gene            16028..16720
                     /locus_tag="C8250_RS31105"
                     /old_locus_tag="C8250_031120"
     CDS             16028..16720
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018561830.1"
                     /locus_tag="C8250_RS31105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031120"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_307811530.1"
                     /transl_table=11
                     /translation="MLPPADSNTEDTLDLTLSDEVLALFNAPDPARSAGAPGADGGLLG
                     GVADWGPTATRAGTFQLVPATVERDLPMISGWMNDPAVAEFWELSGEPRITERHLRGQL
                     DGDGRSVPCLGVLDGTPMSYWEIYRADLDSVARYYPSRPHDTGVHLLIGGVDDRACGLG
                     TTLLRAVADLVLDHRPACARVIAEPDLRNTPSVAAFLAGGFRFSAEVELPGKRAALMIR
                     DRAVRHLL"
     misc_feature    complement(16077..16091)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            16952..18712
                     /locus_tag="C8250_RS31110"
                     /old_locus_tag="C8250_031125"
     CDS             16952..18712
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266984.1"
                     /locus_tag="C8250_RS31110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031125"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_138357319.1"
                     /sec_met_domain="IucA_IucC (E-value: 2.9e-72, bitscore:
                     242.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAKMLAEYAYEAVITPEPDPDADADADLDTGTGTGSRSGTGWSP
                     YRLVLRDDVVYRFRARRGAYGSWSVDAGSITPTGDPLHFLAHGHDTVLDLPGDTTGHLI
                     RELLATLAADVRLDASAVTAAELAALDYADLEGHQTGHPWLVANKGRLGFSAADSALWA
                     PEARRHHRLPWIAVHRDLAQYRGVAALDTPDRLYAEELPPDVRAGFARTITDQGRDPAD
                     YLLLPVHPWQWEETIAPLFAAHLADGSILPLATDNDLRLPQQSIRTFLNTSRPDRRTVK
                     LPLSVLNTLVWRGLPTERTLAAPAVTAWVHGLRDADPFLRDETRVILLGEVASITVEHP
                     LYDRIPGVPYQYRELLGCIWREPLTGRLGPGERARTLAALLHTDPEGRAFTAELVERSG
                     LAPRVWLRHLFAALLPPLLHFLYQYGTVFSPHGENAIVVFDEHDIPVRLAVKDFVDDMN
                     VSAEPLPEHGSMPADVRAVLLTEPPAFLTQFIHSGLFIGVLRYLAPLCEDQLGVPEGDF
                     WGLVRETILRHQDRFPELKERFATFDLLTPRIDRLCLNRNRLHLDGYRDRPDRPHAAVH
                     GTVRNPLSGP"
     misc_feature    17432..17434
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18777..19274
                     /locus_tag="C8250_RS31115"
                     /old_locus_tag="C8250_031130"
     CDS             18777..19274
                     /GO_function="GO:0051219 - phosphoprotein binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012708.4"
                     /locus_tag="C8250_RS31115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031130"
                     /product="FHA domain-containing protein"
                     /protein_id="WP_138357307.1"
                     /transl_table=11
                     /translation="MRDGGEGRDGEDHGTGRPCPECGLAGAVAGQLVCRGCYVPFALMT
                     APTKAAPLTLPGITRRDAPGRALRLVFPDGAAVVEPGGRIRLGRDPQQCPAVRFLGGRD
                     NLSRVHASVGVDPDGSAWITDEGSTNGTFVRGTRITAGERVALRPGDALRLAADVTARV
                     ES"
     gene            complement(19252..20508)
                     /locus_tag="C8250_RS31120"
                     /old_locus_tag="C8250_031135"
     CDS             complement(19252..20508)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="C8250_RS31120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031135"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_138357306.1"
                     /sec_met_domain="Pkinase (E-value: 1.6e-51, bitscore:
                     174.1, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFELAGEIGVGTVLSGRYRLEVALGGGGFGQVYSACDQALGRQV
                     AVKVLTLRPEWADGERSARQGRFRREATAAARLSHPNVAAVHDAGEHSGAPYIVMELLR
                     GKNLRQVLLEQGALPVADVVEYGIQICAGLEHAHGQGLVHRDIKPENLMLLPRGIVKIC
                     DFGLVAERDANVTRYTEPMSILGSPQYFSPEQALGHEVTGRSDLYSLGCVLYALLAASP
                     PFEAGNTVGYAYQHVHEVPEQLAARRPGVPAALAELVHALLAKNPADRPAGAAEAAERL
                     RAAGRPAPAPEPKPAPKPAPKPEMPRTPTVLDRGPQDTAWSRLEEAERLLAAGRFGDAD
                     RCYWNLYQQLSRSGGEGEPAAFAALFGRARVLEGLNGAATVVRRLTDLSARTAAALGPD
                     HALARCVTSYAAVRTPRGR"
     gene            20612..22687
                     /locus_tag="C8250_RS31125"
                     /old_locus_tag="C8250_031140"
     CDS             20612..22687
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983901.1"
                     /locus_tag="C8250_RS31125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031140"
                     /product="ATP-dependent DNA helicase"
                     /protein_id="WP_138357305.1"
                     /transl_table=11
                     /translation="MTKPALTELLHAAVTAVGGVERPGQVTMAQAVETAVDDSAHLLVQ
                     AGTGTGKSLGYLVPALAHGERVVVATATLALQRQLVERDLPRTVQALKPLLRREPQFAM
                     LKGRSNYLCLHRLHEGVPQEEEDGLFDVFEAAAPTSKLGKDLLRLRDWADETETGDRDG
                     LTPGVSDKAWSQISVTSRECLGATKCAYGAECFAEAARERAKLADVVVTNHALLAIDAI
                     EGAPVLPSHEVLIVDEAHELVSRVTGVATGEISPGSVNRAVRRAAKLVNEKAADALLSA
                     SEGFERLMELSLPGRLEEIPEDLGYALAALRDACRQVITAIGETRDKSVQDENAVRKQA
                     LASVEHVHEVAERIVQGSEYDVVWCESHDRFGASLRVAPLSVSGLLREKLFTERSVVLT
                     SATLKLGGDFNGVAASLGLAPEGVEGEDVPPWKGIDVGSPFDYPKQGILYVAKHLAQPG
                     RDSRREDMLDELAELIQAAGGRTLGLFSSMRGAQAAAEDLRGRLDHPILLQGEETLGEL
                     IRTFSEDAATCLFGTLSLWQGVDVPGVNCQLVVMDRIPFPRPDDPLMSARQKAVEERGG
                     NGFMSVAATHAALLMAQGAGRLIRASGDRGVVAVLDPRLATARYGSFLRAGMPDLWYTT
                     DRNQVRRSLAAIDATASAIAETAEEVAEEAEAEETVTEEAAEVAAVDAAEEVPATG"
     gene            complement(22780..23550)
                     /gene="lexA"
                     /locus_tag="C8250_RS31130"
                     /old_locus_tag="C8250_031145"
     CDS             complement(22780..23550)
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526308.1"
                     /locus_tag="C8250_RS31130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031145"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_138357304.1"
                     /transl_table=11
                     /translation="MTTTADTAALTAQDRSQDRLSPMDAMNDETPKPTRSLPGRPPGIR
                     ADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALERKGFLR
                     RDPHRPRAYEVRGSDATHSQPTDTTGKPSASYVPLVGRIAAGGPILAEESVEDVFPLPR
                     QLVGDGELFVLKVVGDSMIEAAIVDGDWVTVRRQPVAENGDIVAAMLDGEATVKRFKRE
                     DGHVWLLPHNAAYQPIPGDEATILGKVVAVLRRV"
     misc_feature    23669..23682
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.92"
                     /tool="antismash"
     misc_feature    complement(23708..23723)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    23709..23722
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.93"
                     /tool="antismash"
     misc_feature    complement(23709..23722)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
     misc_feature    complement(23728..23742)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.05"
                     /tool="antismash"
     misc_feature    23729..23742
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.32"
                     /tool="antismash"
     misc_feature    complement(23773..23788)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.15"
                     /tool="antismash"
     misc_feature    23774..23787
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.65"
                     /tool="antismash"
     misc_feature    complement(23932..23946)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 21.32"
                     /tool="antismash"
     gene            24112..24624
                     /gene="nrdR"
                     /locus_tag="C8250_RS31135"
                     /old_locus_tag="C8250_031150"
     CDS             24112..24624
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105329.1"
                     /locus_tag="C8250_RS31135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031150"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_138357303.1"
                     /transl_table=11
                     /translation="MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCGRRFTTVETAS
                     LMVIKRSGVTEPFSRNKVIAGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAELSTHD
                     VGLAILGPLQDLDLVAYLRFASVYRAFDSLEDFEAAIVELREQLPPTNLRGLDEDLGVP
                     APAPAAD"
     gene            24758..27655
                     /locus_tag="C8250_RS31140"
                     /old_locus_tag="C8250_031155"
     CDS             24758..27655
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092898.1"
                     /locus_tag="C8250_RS31140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031155"
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="WP_138357302.1"
                     /transl_table=11
                     /translation="MTETTNGAARGSRTKGSKGGKGLRIERIHTTPGVHPYDEVVWQHR
                     DVVMTNWRDGSINFEQRGVEFPDSWSVNAVNIVTSKYFRGAVGSPTRESSLKQLIDRVV
                     KSYRKGGEDNGYFASPADAEIFDHELTYALLHQVFSFNSPVWFNVGTAQPQQVSACFIL
                     SVDDSMDSILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADAS
                     AGTIKSGGATRRAAKMVVLDVDHPDVEAFIETKVKEEEKIRALRDAGFDMDLGGDDITS
                     VQYQNANNSVRVNDEFMKAVESGSKFGLRARMTGEIIEEVDAKSLFTKMAEAAWACADP
                     GIQYDDTINHWHTSPETGRITASNPCSEYMHLDNSSCNLASLNLMKFLRDDDKGNQSFD
                     ADRFAKVVELVITAMDISICFADFPTEKIGETTRAFRQLGIGYANLGALLMATGHAYDS
                     DGGRALAGAITSLMTGTSYKRSAELAAVVGPYDGYARNADAHKRVMKQHSDANAVAKRT
                     DDLDVPVWAAATEAWQDVLRLGEKNGFRNAQASVLAPTGTIGLMMDCDTTGVEPDLALV
                     KFKKLVGGGSMQIVNGTVPQALRRLGYQPEQVDAIVAHIAEHGNVVDAPALKTEHYSVF
                     DCAMGERSISAMGHVRMMAAAQPFLSGAISKTVNVPETATVEQIEEVYYEGWKLGLKAL
                     AIYRDNCKVGQPLSAKKKEPAAEAVVPAEVQKVVEYRPVRKRLPKGRPGITTSFTVGGA
                     EGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGMQYGVPLETYVSKFTNM
                     RFEPAGLTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAGERQRHLDTGSYEP
                     GDDDVDVEGLAQSAPRQVEAPAPKAAAPKPVAVAKPENPAAVPAPKQAHNSTELLEIQL
                     GLNADAPLCFSCGTKMRRAGSCYLCEGCGSTSGCS"
     gene            27862..28644
                     /locus_tag="C8250_RS31145"
                     /old_locus_tag="C8250_031160"
     CDS             27862..28644
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145285.1"
                     /locus_tag="C8250_RS31145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031160"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_138357301.1"
                     /transl_table=11
                     /translation="MTELDIHYVGGPTAVIVIGGLRLLTDPTFDAPGEYPMGNRALVKT
                     TGPAVDADAVGAVDAVLLSHDQHPDNLDTSGRAYLASAPLTLSTGSALGRIGGNVTALP
                     NWEHTELTRPDGGTLRITGVPAQHGPDGSEPVVGEVTGFVLSGEGLPTVYVSGDNASLQ
                     VVREIAERFGPFDVAVLFAGAAQTPLLPGADLTLGSVHAAEAAEILGARQVVPLHFEHW
                     GHFTQNGDTLVDAFERAGISDRLHLLKPGERFESGTAR"
     gene            28641..29534
                     /locus_tag="C8250_RS31150"
                     /old_locus_tag="C8250_031165"
     CDS             28641..29534
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015036666.1"
                     /locus_tag="C8250_RS31150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031165"
                     /product="arylamine N-acetyltransferase"
                     /protein_id="WP_138357300.1"
                     /transl_table=11
                     /translation="MTATPAGPVAERETAAGSVAESVWSGDRLDLDAYLARTGYTGGLE
                     RTAETLRGLHRAHTAAIPFENLEVALEREVRLDLDSVQRKLVTERRGGYCYEQNSLFAA
                     VLERLGFVFTAHGARVRTAGPTLRPITHVLLRVVVDGAEWISDTGFGGPGTLEPVELRV
                     GTPAWQGGWAFEVAEEAGGVRVLRSLGARGWSDLYAFAPSPLYPVDLVVLNHYTSTHPL
                     SRFTGQAVVQRVTPQARYSLVRDELTVTRAGAADGAEERRKVPAGELPEVLESTFGLVL
                     AAADTERLGRLHDPAR"
     gene            complement(29568..29972)
                     /locus_tag="C8250_RS31155"
                     /old_locus_tag="C8250_031170"
     CDS             complement(29568..29972)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014145287.1"
                     /locus_tag="C8250_RS31155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031170"
                     /product="VOC family protein"
                     /protein_id="WP_138357299.1"
                     /transl_table=11
                     /translation="MDALHPRLLVEDFATAAEFWTAALRDLLGIEPVKVIPEAGYANWD
                     LNGEGVLVLFSRAAVAAVVGTQALPARPAGQDTSMLVFRVDSVDDAAPLLTAHGAKVVT
                     GPQDRPAWGPGLRTAHLRTPDGTLVELQSY"
     gene            30059..30664
                     /locus_tag="C8250_RS31160"
                     /old_locus_tag="C8250_031175"
     CDS             30059..30664
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1258: Antibiotic biosynthesis monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611911.1"
                     /locus_tag="C8250_RS31160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031175"
                     /product="YdbC family protein"
                     /protein_id="WP_138357298.1"
                     /transl_table=11
                     /translation="MLVKWIRCGVVDRAGFERGQRKWAGLRGQPGFRGQGGGWSRAQPG
                     VAHLFAFWDSRAAYDAFMTGGHDQLAGSQADSYENLGVLLFEHLLDVRVGFEARFADAD
                     LLRVAHSKVRPGRGEHFAEMQKKVWNPAMAGSPGLLRGAFAEGPDSDFLVLSLWISANE
                     RGKYRPAAMTRLAERTELETDVVSVAGDVVDIVQAWTV"
     gene            30801..31469
                     /locus_tag="C8250_RS31165"
                     /old_locus_tag="C8250_031180"
     CDS             30801..31469
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266992.1"
                     /locus_tag="C8250_RS31165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031180"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_138357297.1"
                     /transl_table=11
                     /translation="MGRPRHIVLIRHGESQGNADDTIYERVPDHALELTATGRRQAADA
                     GENLRALFGDEPVQAFVSPYRRTWQTFRGLDLDPSLTHAMEEPRLREQDWGNWQDVDDV
                     QRQRKARDAYGHFFYRFAQGESGADVYDRVGAFLETLYRAFDKPDFPPNVLLVTHGLTM
                     RLFCMRWFHWTVEEFESLSNPGNAESRVLLIGPSGRYTLDRPFARWRLPDPMVDEGFRR
                     "
     misc_feature    31487..31500
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            31526..32440
                     /locus_tag="C8250_RS31170"
                     /old_locus_tag="C8250_031185"
     CDS             31526..32440
                     /EC_number="3.2.2.-"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491599.1"
                     /locus_tag="C8250_RS31170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_031185"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_138357296.1"
                     /transl_table=11
                     /translation="MTAHPVDSENISRALASLRGLAVGDALGSQFFVPSNYQALQNGGL
                     PPGVWQWTDDTEMACSVLAVLAAHGRIDQDALAMSFAEHHDFDRGYGPAVNRMLRLIRQ
                     EGADWRELAAGLFNGQGSWGNGAAMRVAPLGAWYAGDAEQATHQAEISAYTTHQHREAV
                     VGAMAVAAMAALVADPDGPKDPSALLGAVLDLVPTSAVKAGIRRARDMLDYADVATVAA
                     VLGCGRRTSAHDTVPFALWSAARHLDDYQQAFWTTAKAGGDVDTTCAIVGGIIAARPTG
                     QPPAGWLERTEPLPLWVAAPAEA"
ORIGIN
        1 ggtcgacgtg gtcttcggca cccacaacat cggccggctg ccggtgctgc tggagcgggc
       61 caggatcgcc gaagaggcgc aggtcgagat cgccgagtcg ctggaggcgt tcccctccac
      121 gctgccgtcc cgccgcgagt ccgcctacgc cgcgtgggtc tcggtctcgg tgggctgcaa
      181 caacacctgc accttctgca tcgtgcccgc gctgcgcggc aaggaggagg accggcggcc
      241 cggcgacatc ctcgccgagg tggaggcgct ggtcgccgag ggcgtcgtcg agatcaccct
      301 gctcgggcag aacgtgaacg cgtacggctc gggcatgggc gaccgcgagg cgttctccaa
      361 gctgctgcgg gcgaccgggc agatcgaggg gctggagcgg gtgcgcttca cctccccgca
      421 cccgcgggac ttcaccgacg acgtgatcgc cgccatggcc gagacgccga acgtgatgca
      481 ccagctgcac atgccgctgc agtccggctc cgacaccgtc ctcaaggcga tgcgccgctc
      541 gtaccggcag gaccgttacc tcggcatcat cgagaaggtg cgcgcggcca tgccggacgc
      601 cgccatctcc accgacatca tcgtgggctt cccgggcgag accgaggcgg acttcgagca
      661 gacgatgcac gtggtgcgcg aggcgcgctt cgcgcaggcc ttcaccttcc agtactccaa
      721 gcgccccggg accccggccg ccgacatgga cgggcagatc cccaaggagg tcgtccagga
      781 gcgctacatg cggctgtcgg cgctccagga ggagatctcc tggcaggaga acaagacgca
      841 gatcggccgc acgctggagg tcctggtcgc cgagggcgag ggccgcaagg acaaggcgac
      901 gcaccggctg tccggccggg cccccgacag ccgtctggtg cacttcgaga agccggcggg
      961 caccgacccg cgccccggtg acatggccac ggtggagatc acctacgccg ccccgcacca
     1021 cctgctcgcc gagcgccccg cgctctccgt gcggcgcacc cgggccggcg acgcgtggga
     1081 gcagcgcaac gccgcgccca aggcgccggc cggagtgatg ctcgggctgc cgacgatcgg
     1141 cgctccggcg ctgtcgcccg tggtggagag cggctgcggg ctcggctgac gacagcgtcc
     1201 gatcacggtt ccgccggacc ggtgccgacg gtccggcggt gcggccgcgc cagctcacgc
     1261 cgtggctggt cagtttccga ggccggccgt cgtcctcgag ggtgaaggcc cacaggtcgg
     1321 tggcggggat gtcggcgaca ggggtcggaa cggtgtgcac ggtcctgggg aacggtgatc
     1381 agccccatta ggctgcgttc atgctcgtag ccgccgcagt ctgcccgtcc gccccgctgc
     1441 tcgtacccga ggtcgcggcc ggtgccgcgt tcgaactgga cgcgctgcgc gcagcctgcg
     1501 ccgacgcggt cggggtgctc gcggcgtccc ggccggaccg gctggtggtg atcggcccgg
     1561 ccgggcagcc cgaccggggg cggcaccacg agggcgcccg gggctcgttc cgggagttcg
     1621 gcgtggacct ggacgtacgc ctcggcaccg cacccgggac tccgtccgag gacgtcggcg
     1681 ccgaccgcgc gctgccgccc tcgctggccg tcgccgcctg gctgctgcgc ggctgggccg
     1741 ccgctccgct ggagggcctg ggcgtgggcg agccgctcga acaggaccgc tgcgccgcca
     1801 ccggtgccat gatcgcgtca acggcggacc gggtcgcgct gctggtgatg ggcgacggca
     1861 gcgcctgccg caccctcaag gctcccgggt atctggacga gcgcgcggca cccttcgacg
     1921 cctcggtcgc cgccgcgctg gccgccgccg acaccgaggc gctggccgca ctggacgcgg
     1981 aactggcgga gacgctccag gccgcgggac gcgccccctg gcaggtcctc gcgggcgccg
     2041 cgcagggcgc gggcctggcc ggacaactgc tctacgagga cgccccgtac ggtgtcggct
     2101 acttcgtcgc cacgtggacg tagccgccgc tcggccgtag ccgccgactg gtgcggaccg
     2161 ggacggcgga agaccgcggg gccgaagcac ccgcggcctt cccgcgctgg ggtccggggg
     2221 tacctcccag cggtggctgg gggcgtcagg ccggagtgtc cggcccgctt ccctccttgc
     2281 cgctcttcag gtggtccaag gcgcccttcg ccttgtgcac acccgtgtcg atcttgtccg
     2341 tgtacttgcc gtgggtcctg gaatccaccg tccgggcggc cttctcgagc cccgactcga
     2401 tctttccccc gtgctgctgc gcgaggtcgc ccgccttgtt cctggcgagt ccgagtctgt
     2461 ccttgatcgt gtccatcagg cccatccggc accttccctc ggggcggcta cgcgcgggcg
     2521 ccctcaccgg cctcgctgtc ggcggcgtcc gctgtggact gctgcttcgg gatgccgacg
     2581 ggctccgccg cgcccgcggg ctccgcgtcc ccggccggct ccgccgcctc ggcgggctca
     2641 gcgaccgcct cgacgccctc cggctccgcc gtcagagtga cggcttccgc cgcttcggtt
     2701 gacgggtcgg ccgactgacg ccgaaaccat ccgaaaactc ccatttctac tccagaccat
     2761 actcgtgagg tcgaaaatcc gcgttgcccg gggcgcctcg ttgcaccgct cgggtccggc
     2821 cggtccggag aacccggaat ccggcctgcg gaatctctcc agaggcaacg agtccggcag
     2881 cgctgcgtca cgtccctcga tcgtgagggg ggccggaggt ttgggagact ggacacgtgc
     2941 tgcacactcc cggggagcga ccccccgtac ttccgagtaa agatcttgtc atcgccgtcg
     3001 tcggccccac cgcggccggc aagtccgatc tgggcgtagc cctggcccag gccctgaacg
     3061 gtgaggtcgt caacgccgac tccatgcagc tctaccgggg catggacatc ggcaccgcca
     3121 agctcaccac cgacgagcgc cacggcgtgc cgcaccacct gctggacatc tgggacgtca
     3181 ccgaggccgc gagcgtcgcc gagtaccagc ggctcgcccg cgccgagatc gaccggctgc
     3241 acgcggccgg gcggaccccc gtactggtcg gcggctccgg gctgtacgtg cgcggcgcca
     3301 tcgacgcgct ggagttcccc ggcaccgacg ccgccgtccg ggccaggctg gaggcggagc
     3361 tcgccgagca gggctccgcg gcgctgcacg cccggctggc cgcggtcgac cccgaggcgg
     3421 gccgggcgat cctgcccagc aacggccggc ggatcgtccg ggcgctggag gtggtggaga
     3481 tcaccggccg gccgttcacg gccaatctgc cgggccccga ctccatctac ggcaccgtcc
     3541 agatcggcgt cgacgtgccg cggcccgagc tcgacgagcg catcgcgctg cgcgtcgacc
     3601 ggatgtggga cgccggactg gtggacgagg taagggagct ggccgcggtg gggctgcggg
     3661 acggccgcac cgcctcacgg gcgctgggct accagcaggt actcgcctcg ctcgtggggg
     3721 agtgcaccga cgacgaggcg cgcgccgaga ccgtcagggc caccaagcgc ttcgcccggc
     3781 gccaggactc gtggttccgc cgcgatcagc gggttcactg gctctccgcc cggggcccgg
     3841 aactcaccga tcaggcgctg acgttggtcg aagctgcggt tacagcctga tcacgtgatg
     3901 gcatcgggac gcctcagcgt gaggagacgg ccacgcggcc gtgccatcat cgagcaacga
     3961 gttacggcgt cggagaaggg ggagggcgcg tggcgatgga agccggtccc cgagactcct
     4021 cacccgaccg tcatgccgag accgaggcac agctcgggac ggacgaactg ctcgaacccg
     4081 ggtcgctgat cgacccggag gcgatgatcg agccggaact cgttccggtg gagctgcggc
     4141 cgcagcggcg gctgcggatc tggcagctcg ccccgatcgt cgccctcggt gtcggtggct
     4201 ccctgatgtt cgccttcccg ctcgccttcg agttcggtga cggcggcgcg gtcgtggcca
     4261 tgctcggcct gctgctcagc tgctgctccg cgggctgggg catcatggcc gcccgccggg
     4321 tcggctacac ctggcccgga ctgcccgccc gtggctccgg ccgccgtgcg gactggcgct
     4381 tcatcgtcgc ctacaccctg atcagcggcc tgctggcggt cctcgccatc tggcgcgtgg
     4441 cccgcctgcg ctgagccgcc cgccgagcgc cccgcaccgg agcgtgccgg gccggtggcc
     4501 ttacgcttgt ccttgtgacc accacgcagc ccaccacgca ccagggcctg tccttcctca
     4561 agggccacgg caccgagaac gatttcgtca tcgtccccga cgcggacggc cgcatcgagc
     4621 tgtccgcggc ggccgtcgcg cggctgtgcg accgccgggc gggcatcggt ggcgacgggc
     4681 tgctgcgggt cgtgcgctcg gaggcccatc cggaggccgc cggcatggcc ggcgaggccg
     4741 agtggttcat ggactaccgc aacagcgacg gcagcatcgc cgagatgtgc ggcaacggcg
     4801 tccgggtctt cgcccggtat ctgcagcgcg ccgggctgac cgggcccggt gacctggccg
     4861 tggccacccg cgcgggcgtc cgccgggtgc acatcgccaa gacggacgcg gacggcaccc
     4921 tgggcgggat caccgtcggc atgggcgcgg ccgccctgcc cgcgggcgag gtgaccgtca
     4981 ccgtggacgg ccgcagctgg ctggcgagca acgtcaacat gggcaatccg cacgccgtcg
     5041 ccttcgtcgg cagcctggac gacgcgggaa acctgtacac cgcgcccacc gtcacgcccg
     5101 ccgccgcgta cccgaccggc gtgaacgtgg aattcgtcgt cgaccgcggt gagcggcatg
     5161 tggcgatgcg cgtccacgag cggggctccg gcgagacccg ctcctgcggc accggcgcct
     5221 gcgccgtcat ggtcgccgcc gcccgccgcg acggcgcgga cccggccatc accggacgcc
     5281 ccgtcaccta caccgtggac gtccccggcg gccgtctggt gatcaccgag cgcgccgacg
     5341 gcgagatcga gatgaccggc cccgccgtca tcgtcgccga ggggaccatc gaccgggagt
     5401 ggctggacgc accgtcagcc tgacggaccg ccaccgcccg aaaccctgcc gggaatcgga
     5461 ctcctgagcc ccctttccga actggcctcc cgtactgact tcccgcactt gttccctcga
     5521 acgggtgatg gcgatcactc tggacgagag cgcggctgcc gcacgtggtg ggctcggtag
     5581 catcaagcac cggcgcggcc cccattctcc gtggagagcg cccgccgccg gttgacgctg
     5641 ccggaggtgc ccgatgagcg cggacaacgc agtggatgcc gcccccgccc ccgacgatga
     5701 gggccgcagg cgcggacttc gccgcatcga cctgcgcaga ctcggccggg cggcactgct
     5761 cggccccggc ggccgggagt ggggcctgcc cgccggcggc aggggccagc gcgtgccgga
     5821 cgccatcgag caccttgcca aagtccaccg gctgcgccac ccgggggtcg gcgcggccgg
     5881 catcgagacg ctgcgccgcg catatctgct cgccgagtcc tcgcaccgcg gccagatgcg
     5941 caagagcggc gagccgtaca tcacgcatcc gctcgccgtg acgctgatcc tcgccgaact
     6001 cggcgccgag acaacgaccc tgacggcctc tctgctgcac gacaccgtcg aggacacgga
     6061 agtgacactc gatcaggtgc gggaggagtt cggcgaggag gtctgctatc tcgtcgatgg
     6121 cgtcaccaag ctcgaacggg tcgactacgg tgccgcggcc gagcccgaga ccttccgcaa
     6181 gatgctggtc gccaccggaa gcgacgtacg cgtcatgtcg atcaaacttg ccgaccggct
     6241 gcacaacatg cgcaccctcg gggtgatgcg ccccgacaag caggcgcgga tcgcgaaggt
     6301 cacccgggac gtgctcatcc cgctcgccga acggctgggt gttcaggccc tcaagagcga
     6361 actggaggac ctggtcttcg ccatcctcca ccccgaggag tacgccagga cccgcgcgat
     6421 gatccgcgcc aactccgtcc gcccggaccc gctggcggcc gtcgccgacg ccgtgcgggc
     6481 cgtgctgcgc gaggccggga tcgccgccga ggtcgccatc cggccgcggc acaccgtctc
     6541 cgtccaccgg gtgctgctca agcgcggcgc ggacgagctc ggcggctgcg agttcggccg
     6601 gatcctggtg ctcgtcgcgg aggacgccga ctgctacgcc gtcctcggtg agctgcacac
     6661 ctgcttcatc ccagtgatcg cggagttcaa ggacttcatc gcggcgccca agttcaacct
     6721 gtaccagtcg ctgcacaccg ccgtcgccga cgaagagggc cggatcgccg aagtcctggt
     6781 ccgcacacgg cagatgcacc gggtcgccga ggccggtgtc atcgcgctgg gcaatccgca
     6841 caccgtcgac gagcccccgc aggccgccga tggcgaacgc gtcgacccca cccagccggg
     6901 ctggctgtcg cgcctgctgg agtggcagcg cgacgccccc gaccccgaca ccttctggac
     6961 cgcgctgcgc gccgacctcg cccaggaccg cgaggtcacc gtcttctccg cgcacggcgg
     7021 ggacaccacc ggcaccatcc ggctacccgc aggggccagt tgtgtggacg ccgcctacgc
     7081 gctgcacggc gaggccggcc atgcctgcgt cggcgcccgc gtcaacggcc gtctcgcacc
     7141 gctgcgcagc aagctgcggg acggcgacat cgtgcagatc ctgctggacg agaccggcgc
     7201 ctccggcccg tccgccgact ggctggagca cgtccgtaca ccggcggccc ggatcgccgt
     7261 cacccgctgg ctggaactcc atccggtgcc gcccgccgac gaggagcccg ccgcccgcgc
     7321 ggaacgcccc gcgtacagcg cggacaccgc ggccgaggac gaaccggtcg ccgtcaccga
     7381 cctggcgggc gcggccgtcc ggctggcgcg ctgttgtacg ccggtaccgc ccgacgaggt
     7441 caccgggttc gtcatccgcg gcggcacggt cgccgtgcac cgcgaggagt gcccgaccgc
     7501 ggttcggatg atcggcgcgg gacgggagcc ggttcccgtc cggtggcggg gcggccgccc
     7561 cgccggggcc ggattccgcg ccaccctgct ggccgaggcg ctcggccggc cgcggctgct
     7621 cgcggatctc accgaggcca tcgcgggcca gggcgtgggc atcgtctccg cctccgtgga
     7681 acccccgcag gaacaccggg tgcggcacac gtacaccgtc gagctgcccg acgcggaagc
     7741 cctgccgagc ctgatgcgcg ccatgcgatc ggtgccgggc gtctacgacg tctaccgggc
     7801 ccagcgggcg atggccgccg cgcgtcggta acgggcgcga cgcgctctga tccggtccga
     7861 tccgctccat gccggtcggg tccggtcggg ttcggacaac cggccgggcg gaccagggcc
     7921 gatcgggtgt gctgctgcgc gtcgcgcgtc cccggccgcc gccccctgat agcggtagcg
     7981 catgatcccc atcacgccgc gcagcggcgc cgtgctggcg gcgttcgccg ccgtactgac
     8041 cctgaccgcg gcggacctgc ccggcgatcc cgccgtatcg acgtcgggtc tcggcgaccg
     8101 gctctatccc gacctcggca atcccggcta cgacgtggcc gcgtacgacc tctccttcga
     8161 ctatcacggc caggaccggc cgctggacgc cgtcacccgc atcaaggccc gcgcgacggc
     8221 gccactgacc gggttccatc tggacttcgc cgccggcacg gtctcatcgg tgcaggtcaa
     8281 cgggcatccg gcggtctaca cccgggagcg cgaggaactc gtcgtcaccc ccgaggagcc
     8341 ggtaccggac ggcggcgagc tgctgatcgc cgtcacgcac accagcgatc cgcgcgccgc
     8401 gaacaccggc tgggtgcgga ccgccgacgg actggcgatg gccaaccagg ccgatgccgc
     8461 ccacagcgtc ttcccgtgca acgaccatcc ctcggacaag gccgccttca ccttccacgt
     8521 cacggccccc aaggacctca ccgtcatcac caacggcgtc ccggacgccg tccccgaggc
     8581 cgcgcccgcg tccgctctca cctggacgta ccgtcccgcg agcccgatgg ccaccgagct
     8641 cgcgcaggtc tccatcggcc gctccgccgt actgcaccgc gccggtccgc acgggctggt
     8701 gctgcgcgac gtcgtcggag ccgccgaccg cgaccggctg gaggcccggc tcgcgatgac
     8761 ccccgggcag atctcctgga tggaggagca ggtcggcccc tacccgttcg agacgtacgg
     8821 gatcctcagc gccgacacca ccaccggctt cgagctggag acccagaccc tctcgctctt
     8881 cgagcgccgc gtcctgctcg cccccgaggc gctggcagcc ccgctgatgg tgcacgagct
     8941 cgcccaccag tggttcggcg acagcgtcac ccccgcggcc tggtcggacc tctggctcaa
     9001 cgagggccac gccacctggt accagtggct gtacaacgcg cagaagtacg gcgtcggcct
     9061 cgaccagcag gtccgcgccg cctacgaggg cgacaaccgg gtacgggcgg cggacggccc
     9121 gcccgccgaa ccgaaggtgc ccgaaccggg caagctcggc atcttccgga acaacgtcta
     9181 cgacggcggg gcgctcgccc tgtacgccct gcgccaggag atcggcgccc ccgccttcca
     9241 gcgccttgag cgcgcctggg tggcccgtca ccaggacggg aacgcctcga cggccgactt
     9301 caccgctctc gcctccgagg tcgctgagcg ggacctcagc ggcttcctgc acgcctggct
     9361 gtacgggacc gtcaccccgc cgatgcccgg tcacggcgac tgggtcgccg gcgcggccag
     9421 ggcccgtgcg gcgacggcgg cgaaacccgc gtgacccccg gcggcgggcg tgcgaccatc
     9481 gttatgacgg acaacacgcc cgtccccatc ccagccgctc gaccaaagga tccaatgacc
     9541 tcctcttcct cctcttcaaa cgaccgccag cgcctccccg agagccttcg cgcagacgcc
     9601 ctgatggaag aggacgtcgc ctggagccac gagatcgacg aagagcggga cggtgctcag
     9661 ctcgaacgct ccgaccgtgc ctcgctgcgc cgcgtcgtgg gtctgtccac cgagctggag
     9721 gacgtcaccg aggtcgagta ccggcagctc cgtctggagc gcgtcgtact cgtcggtgtc
     9781 tggacctccg gaaccgtgca cgacgcggag aactccctcg cggagctcgc cgccctcgcg
     9841 gagaccgcgg gcgccctggt gctcgacggc gtgatccagc gccgtgacaa gccggacccg
     9901 gccacgtaca tcggctcggg caaggcgcgc gagctgcggg acatcgtgca ggagacaggc
     9961 gccgacacgg tcgtctgcga cggtgaactc agccccggac agctcatcca gctcgaagac
    10021 gtcgtcaagg tcaaggtggt cgaccgcacc gccctgatcc tcgacatctt cgcccagcac
    10081 gccaagtccc gtgagggcaa ggcccaggtc tcgctcgcac agatgcagta catgctgccg
    10141 cgcctgcgcg gctggggtgc ctcgctctcc cgccagatgg gcggtggcgg ctccagcggc
    10201 ggcggggccg gcggtggtgg gggtatggcc acccgcggtc ccggtgagac caagatcgag
    10261 accgaccggc gccgtatccg cgagaagatg gcgaagatgc gccgggagat cgcggagatg
    10321 aagaccggcc gtgacctcaa gcggcaggaa cgcaagcgca acaaggtgcc ctccgtcgcg
    10381 atcgccggct acaccaacgc gggcaagtcc tcgctgctca accggctcac cggcgcgggc
    10441 gtgctggtgg agaacaccct gttcgccacc ctcgacccga ccgtgcgccg ggcggagacc
    10501 cccggcggcc ggctgtacac gctgaccgac accgtcgggt tcgtccggca cctgccgcac
    10561 cacctggtcg aggcgttccg ctccaccatg gaggaggtcg cggaagccga cctcatcctg
    10621 cacgtggtgg acggctcgca cccggtcccg gaggagcagc tcgccgccgt gcgggacgtc
    10681 ttccgcgagg tcgaggcgct caaggtgcgc gagatcgtcg tcatcaacaa ggcggacctg
    10741 gccgacccgc tcgtcctgca gcgcatgctg cggaacgaga agcacgccat cgcggtgtcc
    10801 gcccgcaccg gccagggcat cgacgagctg ctcgcgctgc tcgacgagga gctgccgcgg
    10861 cccgaggtcg aggtcgacgt cctcgtgccg tacagccagg gcgcgctcat cgcccgggcg
    10921 cacgccgacg gcgaggtgct ctccgaggag cacaccggcg agggcacgct gctcaaggca
    10981 cgggtgcacg aggacctggc cgccgagttc gcgtccttcg cgctcgtcgc caagcactga
    11041 cccgtccgcc ggagcaccga cggaagggcc cgtccccgat gggggcgggc ccttccgtgt
    11101 gacctgctac cggctggacg ccggtgttac ttgaactgct tgctcacctt gtcgtacacg
    11161 gccttcgcct cggcgcccag gtgcgggccc gccagccagg tagccgtgac cgggccgatc
    11221 gaggtgttgc tgaccagcga cacctgattg ttcgccgggt tcttggcgta ccagccgccg
    11281 ccggacgaac cgccggtcat cgtgcagccg agccggtact cggtcggctg atcggcgaag
    11341 agcgacagcc ggccggcctt gcccgtgcag ttgaacagcc gctggccgtc gaagggcggc
    11401 gcggccgggt agccccaggc gccgatgttg cccatcttcg tcacggacgg agcgttgaac
    11461 cacaccggaa gggcggaacc gaccttctcc tccagcgact tggtgccgct cgccttgtcc
    11521 ggagtcacgt gcagcaccgc gaagtcgtac ggggagccct tgcccccggt ctccgcgccg
    11581 ttcgcgatcc actggtcgga ggtggccgcg ccgtcggccc agaacacgcc gagcggggcg
    11641 agctcgtcgc gcttggcgcc cttcagctgc gcctcggtcc tgcccgcgtc gttgtacgac
    11701 gggacgaaga tgacgttgcg gtaccagccg cccgcgccac ccgcgtgcac acagtggccc
    11761 gcggtccaca ccaggttgga cttgcccggg tgcgccgggt cctgcaccac ggtgccggag
    11821 cagaccatcg agcccttggg gccgtcgaag aagatcttcc cgtcgccggg gccgttctcg
    11881 tggtacggcg cgtcaacggc cttggccttg ttgaccgcgg gcaccgcgtc cgtcttgccc
    11941 ttgtccgccg cgacgtcgtc gggcaccttc ttgtcgttct gctccgcgcc cttcatccgg
    12001 tcgttgtccc acagaccgtc gatgaccggg ttgatgaagt cggaggcctt gcgcagccac
    12061 tggtccttgt cccagttctt ccaggctccg tccttgtacg ccttcttcca cttctcgagg
    12121 tccccgaggc tggtgggcag ggcggagggg agcttcgggc cgtccgcgct cgtgaccggg
    12181 gcgctcggct tgggatccgc cttgtcgtcg gacggcccgc aggcggtggc cgagaccgcg
    12241 agcagggccg cgaccgcggc ggcggccagt ggccggctta tggatggcat gggtggtgtc
    12301 cccctggtcg tctaacggca gttcaccccg gcgaaggggc ggtcccccac tatgccgggt
    12361 gctgtgaggg acggttcgcg ccgggtccgc ggttccgccc cgaaagatct cccggccgac
    12421 cgtgatcgga ccaggggcgc gtcgttagtg cggatggggg acgtcgaccg gaggagtgag
    12481 cacgtggccg ccatccagag cgggccggac caactggccg cgtcggcaga cgacttcgtc
    12541 gcgggagagg ggatcctgcg gcggcagtcg ctgcgtgagt ccgcggcccg cacctacgcc
    12601 cgctcgctgc ccgtcgtccc ggtcagagcc cgcgggatga cggtcgaggg cgccgatggc
    12661 cgccgctatc tggactgcct gtccggcgcg gggacgctgg cgctcgggca caaccacccg
    12721 gtcgtcctgg aggcgatccg cgcggtcctg gactccgggg ccccgctgca cgtcctcgat
    12781 ctggccacgc cggtgaagga cgccttcacc accgccctgt tcgagacgct gccgccggaa
    12841 ctggccgccc acgggcgggt gcagttctgc ggaccggccg gtacggacgc ggtcgaggcg
    12901 gccatcaagc tcgtccgcaa cgccaccggc cacgccggac tgctggcctt caccggcgcc
    12961 taccacggga tgaccgcggc cgcgctggcc gcgaccgggg acaccgcggc gcgcgccacg
    13021 gtcggcgagg ccgacgcgcg ggtgacgcgg ctcccgtacc cgtacgagta ccgctgcccg
    13081 ttcggcaccg gcggcgaccg cggggcggag ctgtccgccc ggtggaccgc cagcctgctg
    13141 gacgacccca agggcggcgt ccagccgccc gccgggatgc tgctcgaagt ggtgcagggc
    13201 gagggcgggg tgatccccgc gcccgaggcg tggctgcgcc ggatgcggga gatcaccgcc
    13261 cggcgcggca tcccgttgat cgtcgacgag gtacagacgg gcgtcggacg caccgggacc
    13321 ttctgggccg tcgagcagag cgggatcgtg ccggacgtga tggtgctctc gaaggcgatc
    13381 ggcggcagcc tcccgctcgc cgtcatcgtc taccgggagg agctggacac ctggcggccc
    13441 ggcgcccacg cgggcacctt ccggggcaac cagctcgcca tggcggcggg cgccgtcacc
    13501 ctgaagtacg tccgtgagca cggcctggac gtgcgggccg gcaccctcgg cagccggatg
    13561 tcggcccggc tgcgcggact ggccgcgcac cacccgtgca tcggcgatgt gcggggccgc
    13621 ggtctgatga tcggcctcga actcgtcgac accgaggcag aacccgacga ttacgggtcg
    13681 ctgcccgccg cgccccggct cgccgccgcc gtgcagcagg aggcgctgcg gcgcggtctc
    13741 atcatcgaac tcggcggccg gcacagcagt gtcgtccggc tgctcccgcc gctcaccatc
    13801 accgacgagc aggccgaggc ggtgctcgac cggctcgcgg actcgatcgc ggcggccgag
    13861 cgggcggttt ccggggctcc cggggctccc ggagctcctg ggacttctgg gggttccggg
    13921 actgcgggaa ctcccggcgc tcgcgtcggt cctggattct ccggtgcgtc cgcgggcgcc
    13981 ggagcggtgg aggagcgcgc atgacgagcc cacaggcgac ggccgagtac ccccagacct
    14041 ccgggccgac gggccccacc gacacacgga gtaccggcat gagcgtatgc cccggcacga
    14101 acgccgaccc tgccgccgac agcacgccgg cccaggccgg cgcggcccag caggacaggc
    14161 cgaccctcca cggcgggccg gctcaccaga ccggcacggc cgttcaggac agcacggccc
    14221 tcgtaccgcc gcagtcgcgg cgggcggccc tgccgctgcc gggcgagccc gatcccctcg
    14281 aagcgtccga cgcctacgcg gcggccgacg cggcgtcgat cgagagcctg ctgcgctgct
    14341 gggtgcgcga gaccgcgctc cccgagccgc gggacggcgt gctgcgtgta ccgctccccg
    14401 ccagcggcac cggcttcgac gtccgggtcc ggcactggtc agcgaccggg caccaccggt
    14461 tcggcaccgt acggctcgcc ctcgccgacc aggtgccgct gaccgccgtc tgcctggcgg
    14521 cgctgctggc gcgcgaggcc ggcacggatc cggccgaggg cggcgacctg atcggccggg
    14581 tcgccgactc cgcccgccgt accgccctgt tcctcaccga ccggcgggag cggcccgcgg
    14641 cgcccgccgc cacggatccg ttcctcgaag ccgagcagtc gctcctcctc ggccacccgc
    14701 tgcaccccac gcccaagggc agggaggggc tctccgaggc ggagtcccgc gcctactcgc
    14761 cggaactgcg cggctccttc ccgctgcact ggttcgccgt cgaccgctcc ctgatcgcca
    14821 ccgactcggc ctggaccgaa cgcggccgcg ccattcccgc cgaacagctc ctcaccgacc
    14881 tcgcaggccc cggcctcgaa ctccccgacg gcgccgccgc cctgcccctg cacccatggc
    14941 aggcccgcga ggtccagcac cggcccgagg tgcgggaact cttcgagacg ggtcagctgc
    15001 gtgacctcgg cccgctcggc gatccctggc accccacctc ctccgtgcgg accgtgtacc
    15061 ggtccggcgc ccccgcgttg ctgaagctct cgctggcgct gcgcatcacc aactcccgcc
    15121 gcgagaacct ccgcaaggaa ctccggcgcg gcaccgaggt ccaccggctg ctgcgcagcg
    15181 gactcgccga gcagtggcgc gccgcgcacc ccggcttcga catcgtccgc gaccccgcgt
    15241 ggctcgcggt gaacgcgccg ggcggagagc cgctccaggg cctggacgtg gtgctgcggc
    15301 acaacccgtt cggccccggc gaccagaccc actgcctggc gggcctcacc tcgccgcgcc
    15361 cctggccggg acaggccgcg cccgccctgc gctcccgcct ggccgacctc accggccgcc
    15421 tcgcggcccg gaccggacgc ccggccgcgg ccgtcgccac cgagtggttc ctgcgctatc
    15481 tggacgccgt cgtccgtccc gtcctctggc tggacggaga ggcggggatc gccctggagg
    15541 cccaccagca gaacaccctc gtcctgctgg acgccgacgg ctggccgtcc ggcggccgct
    15601 accgggacaa ccagggctac tacttccggg agtcccaccg ggccgccctg gagcgcaggc
    15661 tgcccgggat cggcgcggag agcgacacct tcgtcgcgga cgccatcgcc gacgagcgct
    15721 tcgcctacta cctcggcatc aacaacgtcc tcggcctgat cggcgcgttc ggctcccagg
    15781 ggctggccga cgaacgcctg ctcctcgccg ccttccgccg gttcctcggc ctggcggcgg
    15841 ccaccggccg ctcccgtctg ccggaacagc tgctcggggc cgcgacactg cgctgcaaag
    15901 ccaatctgct gacccggctg cacggtatgg atgaactcgt cggcccggtc gacacccagt
    15961 ccgtctacgt gacgatccgc aatccgctgg ccgcctgagc ggtccgaccg caggagagga
    16021 gggagccgtg ctgccgcccg ccgactccaa caccgaggac accctggacc tgacactgtc
    16081 cgacgaggtc ctcgccctct tcaacgcgcc ggatccggcg cggtccgccg gggctccggg
    16141 cgcggacggc ggtctgctcg gcggggtcgc ggactggggg ccgacggcca cccgggcggg
    16201 caccttccag ctcgttcccg cgaccgtcga acgcgatctg ccgatgatct ccggctggat
    16261 gaacgacccg gccgtcgccg agttctggga gctctccgga gaaccgcgga tcaccgagcg
    16321 gcatctgcgc ggccagctcg acggcgacgg ccgcagcgtc ccctgcctcg gcgtcctgga
    16381 cggcaccccc atgagctact gggagatcta ccgggccgat ctcgactccg tcgcccgcta
    16441 ctacccctcc cgaccccatg acaccggggt gcatctgctg atcggtggtg tcgacgaccg
    16501 ggcctgcggc ctgggcacca ccctgctgcg agccgtcgcc gacctcgtgc tcgaccaccg
    16561 gccggcctgc gcgcgcgtca tcgcggaacc cgacctgcgc aacaccccct ccgtcgccgc
    16621 cttcctcgcc gggggcttcc ggttctccgc cgaggtggag ctgcccggca aacgggcggc
    16681 tctgatgatc cgcgaccgtg ccgtgagaca tctcctctga ccgcctgacc gcctgaccgc
    16741 ctgaccgcct gaccgcctga ccgcctgacc gcctgaccgc ccgaccgcac cctgaccgcc
    16801 cgaccgcacc ctgacctttc tgatctcccg ggccccttcg ggacctccgc cgacccctgt
    16861 ccgccgccgc gctgtccccc gcagaggagc accgaccttg accatcccgc caccgctccg
    16921 aggcaccggc tggcagctcg ccgcccgccg catgctggcc aagatgctcg ccgagtacgc
    16981 gtacgaagcc gtcatcaccc cggagccgga tcccgacgcc gacgccgacg ccgacctcga
    17041 caccggaacc ggcaccgggt cccgttccgg gaccggctgg tcgccctacc ggctggtgct
    17101 gcgcgacgac gtcgtctacc ggttccgcgc ccgccgcggt gcctatggca gctggtccgt
    17161 ggacgccggc tccatcacgc ccaccggcga cccgctgcac ttcctcgccc atggacacga
    17221 caccgtgctg gacctgccgg gcgacaccac ggggcatctg atccgcgaac tcctggcgac
    17281 gctggccgcc gatgtccggc tcgacgcctc cgccgtcacc gccgccgagc tcgccgcact
    17341 ggactacgcc gacctcgaag gccaccagac cggccacccc tggctcgtcg ccaacaaggg
    17401 ccggctcggc ttctccgccg ccgactccgc cttatgggct cctgaggccc gccggcacca
    17461 ccgccttccc tggatcgccg tccaccgcga cctcgcccag taccggggcg tcgccgccct
    17521 ggacaccccc gaccggctct acgccgaaga actccccccg gacgtacgcg ccggcttcgc
    17581 ccgcaccatc accgaccagg ggcgcgaccc cgccgactac ctcctgctgc ccgtccaccc
    17641 ctggcagtgg gaggagacga tcgcacccct cttcgccgct catctcgccg acggttccat
    17701 cctgcccctc gccactgaca acgacctgcg gctgccccag cagtcgatca ggaccttcct
    17761 caacaccagc cgcccggacc gccgcacggt caagctgccg ctgtcggtcc tcaacaccct
    17821 cgtgtggcgc gggctgccca ccgagcgcac cctcgccgcc cccgcggtca ccgcctgggt
    17881 gcacggtctg cgggacgccg accccttcct gcgcgacgag acccgggtga tcctgctcgg
    17941 cgaggtcgcc tcgatcaccg tcgaacaccc gctgtacgac cggatcccgg gcgtgcccta
    18001 ccagtaccgc gaactcctcg gctgtatctg gcgcgagccg ctcaccggcc ggctcggccc
    18061 cggcgagcgg gcccgtacgc tcgcggcgct gctgcacacc gacccggaag ggcgcgcctt
    18121 caccgccgag ctcgtcgaac gctccgggct ggcgccgcgc gtctggctgc gccatctgtt
    18181 cgcggccctg ctgcccccgc tgctgcactt cctgtaccag tacgggacgg tcttctcccc
    18241 gcacggcgag aacgccatcg tcgtcttcga cgagcacgac attcccgtgc ggctcgccgt
    18301 caaggacttc gtcgacgaca tgaacgtctc cgcggagccg ctgccggaac acgggtcgat
    18361 gcccgcggac gtccgcgcgg tgctgctcac cgaacccccg gccttcctga cccagttcat
    18421 ccactccggg ctcttcatcg gggtgctccg gtacctcgcg ccgctgtgcg aggaccagtt
    18481 gggcgtcccg gaaggcgatt tctgggggct ggtccgcgag acgatcctgc ggcaccagga
    18541 ccgcttcccc gagctgaagg agcgcttcgc gaccttcgac ctgctcaccc cccggatcga
    18601 ccggctgtgc ctcaaccgca accggctgca cctcgacggc taccgggacc gtcccgaccg
    18661 cccgcacgcc gccgtccacg gcaccgtccg caaccccctg agcggcccct gacgcggctg
    18721 tgtcccggct ggcgataccg tgacgggata ccacgggaga cagaagcggg ggcgccatgc
    18781 gcgacggcgg tgagggccgt gacggcgagg accacggcac cggcaggccg tgcccggagt
    18841 gcggcctcgc cggcgcggtc gcgggccaac tcgtctgccg gggctgctac gtacccttcg
    18901 cgctgatgac ggcgcccacg aaggccgcac cgctgacgct gccgggcatc acccgccgcg
    18961 acgcgcccgg ccgtgcgctg cggctcgtct tccccgacgg tgcggcggtc gtcgagccgg
    19021 gcggccggat ccggctcggc cgggatccgc agcagtgccc ggccgtccgc ttcctcggcg
    19081 gccgcgacaa cctgtcgcgg gtccacgcca gcgtcggcgt cgaccccgac ggctccgcct
    19141 ggatcaccga cgagggctcg accaacggca ccttcgtgcg cggcacccgg atcaccgcag
    19201 gagagcgggt ggcgctgcgc ccgggcgacg cgctgcggct cgccgccgat gtcaccgccc
    19261 gcgtggagtc ctgaccgccg cgtaggacgt cacacagcgc gccagcgcat ggtcggggcc
    19321 cagcgccgcc gccgtacgcg ccgacagatc cgtcagccgg cggacgaccg tcgccgcgcc
    19381 gttcagcccc tccaggaccc gtgcccggcc gaacagtgcg gcgaacgcgg ccggctcgcc
    19441 ctccccgccc gacctgctga gctgctggta cagattccag tagcagcggt cggcgtcgcc
    19501 gaaccggccg gcggcgagca gccgctcggc ctcctccagc cgcgaccagg cggtgtcctg
    19561 cggtccgcgg tccagcacgg tcggcgtccg gggcatctcg ggcttcgggg ccggtttcgg
    19621 agccggcttc ggttccgggg ccggcgcggg ccggcccgcc gcgcgcagcc gctccgcggc
    19681 ctccgcggcg cccgccggcc ggtccgccgg gttcttggcg agcagcgcgt gcaccaactc
    19741 ggcgagcgcg gcgggaaccc cggggcggcg ggcggccagc tgctccggca cctcgtgcac
    19801 atgctggtac gcgtagccga cggtgttgcc cgcctcgaac ggcggagacg ccgccagcag
    19861 tgcgtagagg acgcacccca gtgagtacag gtcggagcgg ccggtcacct cgtgccccag
    19921 cgcctgctcg ggggagaagt actgcggcga ccccaggatg gacatcggct ccgtgtaccg
    19981 ggtgacgttc gcgtcccgct ccgccaccag cccgaaatcg cagatcttga cgatgcccct
    20041 gggcagcagc atcaggttct ccggcttgat gtcccggtgg accagtccct ggccgtgcgc
    20101 gtgctccagc cccgcgcaga tctggatgcc gtactccacc acgtcggcga ccggcagggc
    20161 gccctgctcc agcaggacct gccgcaggtt cttgccacgc agcagttcca tcacgatgta
    20221 cggcgccccg gagtgctcgc ccgcgtcatg gacggcggcc acgttcgggt ggctcagccg
    20281 ggccgcggcg gtggcctccc ggcggaacct gccctgccgc gccgaccgct cgccgtccgc
    20341 ccactcgggg cggagcgtca gtaccttgac cgccacctgc cggccgagcg cctggtcgca
    20401 cgccgagtac acctgcccga agccgccgcc acccagcgcg acctccagcc ggtaccggcc
    20461 gctgagcacc gttccgacgc cgatttctcc ggccaactcg aacgacatgc gccagaagtt
    20521 agcaccggac gccggattgc gtacggcgaa cgatcaccgc gtcccggggc aggaccgtgt
    20581 tgtcagtgcg cccccttagg ctggtttccc tatgacgaag cccgccctca ccgaactcct
    20641 ccacgcagcc gtcaccgcgg tcggcggcgt ggagcgcccc ggccaggtca cgatggccca
    20701 ggccgtcgag accgccgtgg acgacagcgc ccatctgctc gtccaggccg gcaccggcac
    20761 cggaaagtcc ctcggctatc tggtgcccgc cctcgcccac ggcgagcggg tggtggtcgc
    20821 gaccgccacc ctcgccctgc agcggcagct ggtcgagcgt gacctgccgc gtaccgtcca
    20881 ggcgctgaag ccgctgctgc gccgcgagcc gcagttcgcc atgctcaagg gccggtcgaa
    20941 ctatctctgt ctgcaccgcc tgcacgaagg ggtgccgcag gaagaggagg acggtctctt
    21001 cgacgtcttc gaagccgcgg cgcccaccag caagctcggc aaggacctgc tccggctgcg
    21061 cgactgggcg gacgagaccg agaccggcga ccgggacggc ctcacgccgg gcgtctccga
    21121 caaggcctgg tcgcagatct ccgtcacctc gcgcgaatgc ctcggcgcca cgaagtgcgc
    21181 ctacggcgcg gagtgcttcg ccgaggcggc ccgcgagcgc gccaagctcg cggacgtggt
    21241 ggtcaccaac cacgccctgc tcgccatcga cgccatcgag ggcgcgccgg tcctgcccag
    21301 ccacgaggtc ctgatcgtgg acgaggccca tgagctggtc tcccgtgtca ccggtgtcgc
    21361 gaccggtgag atcagccccg gtagcgtcaa ccgcgccgtc cggcgggccg ccaagctcgt
    21421 caacgagaag gccgccgacg cgctgctcag cgcctccgag ggcttcgagc ggctgatgga
    21481 actgtcactg cccggccgcc tggaggagat cccggaggac ctcggctacg cactggcggc
    21541 gctgcgcgac gcctgccgcc aggtgatcac cgcgatcggc gagacccgcg acaagtccgt
    21601 ccaggacgag aacgcggtgc gcaagcaggc gctcgcctcg gtcgagcacg tccatgaggt
    21661 cgccgagcgc atcgtgcagg gctccgagta cgacgtggtc tggtgcgaga gccacgaccg
    21721 gttcggcgcc tcactgcggg tcgctccgct cagcgtctcc ggcctgctgc gcgagaagct
    21781 cttcacggaa cgttccgtgg tgctcacctc cgccaccctc aagctcggcg gcgacttcaa
    21841 cggggtcgcg gcctcgctcg gcctggcccc ggagggcgtc gagggcgagg acgtgccgcc
    21901 gtggaagggc atcgacgtcg gctcgccgtt cgactacccc aagcagggga ttctctacgt
    21961 cgccaaacac cttgcccagc cgggccgcga cagccgccgc gaggacatgc tggatgaact
    22021 cgccgagctg atccaggccg cgggcggtcg cacgctgggg ctgttctcct cgatgcgggg
    22081 cgcccaggcg gcggcggagg acctgagggg ccggctcgac catcccatcc tgctgcaggg
    22141 cgaggagacg ctcggggagc tgatccgcac cttctccgag gacgcggcca cctgtctgtt
    22201 cggcacgctc tcgctctggc agggcgtgga cgtgccgggg gtgaactgcc agctggtggt
    22261 gatggaccgg atcccgttcc cccgcccgga cgacccgctg atgagcgcgc ggcagaaggc
    22321 tgtcgaggag cgcggcggga acggcttcat gtcggtggcc gccacgcacg cggcgctgct
    22381 gatggcgcag ggcgccggcc ggctgatccg ggcctcgggc gaccggggcg tcgtcgccgt
    22441 cctggacccc cggctcgcga ccgcgcggta cggcagcttc ctgcgggccg gcatgccgga
    22501 cctctggtac accaccgacc gcaaccaggt gcgccgctcg ctggcggcca tcgacgcgac
    22561 ggcgagtgcg atcgccgaga ccgcggaaga ggtggctgag gaagccgagg ccgaggagac
    22621 ggtgacggag gaagcggccg aggtggcggc ggtcgacgcg gcggaggaag tacccgccac
    22681 cggctgagcc ctgaacgtcg gacgtcgccc tggcgatgcg gacatggcag ggccccggaa
    22741 ccggcgcaga ggttccgggg cccggtcgta aggggtcgtt cagacccggc gcagtaccgc
    22801 caccaccttg ccgaggatcg tcgcctcgtc accggggatg ggctggtaag cggcattgtg
    22861 cgggagcagc cagacatggc cgtcctcgcg cttgaagcgc ttgacggtcg cctcgccgtc
    22921 gagcatggcg gcgacgatgt cgccgttctc ggcgacgggc tgacggcgga cggtgaccca
    22981 gtccccgtcg acgatggcgg cctcgatcat cgagtcgccg accaccttga ggacgaacag
    23041 ctcgccgtca cccaccagct ggcggggaag cgggaagacg tcctcgaccg attcctcggc
    23101 gaggatcgga ccgccggcgg cgatccggcc gacgagcggc acgtacgacg cggagggctt
    23161 gccggtggtg tccgtcggct gcgagtgcgt ggcgtcggag ccgcggacct cgtaggcgcg
    23221 cgggcggtgc gggtcgcggc gcaggaatcc cttgcgctcc agcgccatca gctggtgggc
    23281 gaccgaggag gtgctggaca gaccgacggc ctggccgatc tcgcgcatgg acggcgggta
    23341 gccacggcgc tggaccgaat cgcggatcac ttcgatgacc cggcgctgac ggtcggtgag
    23401 gccggagctg tccgcgcgga tcccgggcgg ccggccgggg agcgagcggg tgggcttggg
    23461 cgtttcgtcg ttcatcgcat ccatcgggct gagccgatcc tgggagcggt cctgggcggt
    23521 caatgctgcg gtgtctgcgg tggtggtcac ggcggcccct ctcgagatgt tctccctgtg
    23581 acagacgctt cgcagactgc ccggcggcaa ggtctccacg tcctacgacc gcaccaagtg
    23641 cgtgcggtcg gcccgctcag ctgtcgcgga cagttagtac aacggtagtg ggtttcgaaa
    23701 ggttgcgcca aacacacgtt cgagtgaaat tttgtaaatc acctgacgtg atcaaggtat
    23761 cgggtgtata gaccgaacag tcattcgatt cctgatggga gccgggatcg ccggcgggcc
    23821 gcgcccccag tgtcgcaccg ccgacctccc accacgccga ggcgcgacgt cgcgtaagct
    23881 ccgacgcgcc gcgccgccgc gacacgcgga atgtcgcgct tggggctctg gcaccagatc
    23941 tagtggttaa gtaagtgcca gccacccacc agtagtggtc ccagtgggtc aacccctcag
    24001 tggatcgcct atgcttgggg ctgttcccag gggttgaggc cagaccccgg gagcgtcatc
    24061 gtcgtgcgct cagccgccgg tacgggctga atgaaggagg ggatagggaa catgcactgc
    24121 cccttctgca gacaccccga cagccgtgtg gtcgacagcc gcaccacgga cgacggcacc
    24181 tcgatccgcc gccgccgtca atgccccgac tgcggccgcc gcttcaccac ggtggagacg
    24241 gcgtccctga tggtgatcaa gcgcagcggc gtcacggaac ctttcagcag gaacaaggtc
    24301 atcgcaggcg tccgcaaggc gtgccagggc cgccccgtca ccgaggacgc gctcgcccag
    24361 ctcgggcagc gcgtcgagga ggcggtcagg gcgaccggca gcgccgagct ctcgacccac
    24421 gacgtcggtc tggccatact cggccccctg caggatctcg acctggtcgc gtacctgcgc
    24481 ttcgcctcgg tctaccgggc cttcgactcg ctcgaggact tcgaggccgc catcgtcgag
    24541 ctgcgcgagc agctcccacc cacgaacctt cgcgggctcg acgaggacct cggggtcccc
    24601 gcgcccgccc ccgccgctga ctgaccgagc gacggccgat cagcggcagt acccacagat
    24661 ttgccgaggc gcgctgcgcc gaggcgtagg acaacgaacc gtgcggcggg atgatccgcg
    24721 cacttctagg cgttttgcct gtattgggag gcggcacatg actgagacga cgaacggcgc
    24781 ggcacgagga tcccggacca agggatccaa gggtggcaag ggcctgcgga tcgaacgtat
    24841 ccacaccacc ccgggcgtgc acccgtacga cgaggtggtg tggcagcacc gcgacgtcgt
    24901 gatgaccaac tggcgcgacg gctcgatcaa cttcgagcag cggggcgtcg agttccccga
    24961 ctcctggtcg gtgaacgcgg tcaacatcgt caccagcaag tacttccgcg gcgcggtcgg
    25021 cagcccgacc cgcgagtcga gcctgaagca gctcatcgac cgtgtggtga agtcctaccg
    25081 caagggcggc gaggacaacg ggtacttcgc ctccccggcc gacgccgaga tcttcgacca
    25141 cgagctgacc tacgccctgc tgcaccaggt gttcagcttc aactcgccgg tctggttcaa
    25201 cgtcggtacc gcccagccgc agcaggtctc cgcctgcttc atcctctccg tcgacgactc
    25261 gatggactcg atcctggact ggtacaagga agaggggatg atcttcaagg gcggctccgg
    25321 cgccggcctg aacctctccc gcatccgctc ctccaaggag ctgctctcct ccggcggcaa
    25381 cgcttccggc ccggtctcct tcatgcgcgg cgccgacgcg tccgccggca ccatcaagtc
    25441 gggcggcgcc acccgccgcg ccgccaagat ggtcgtcctg gacgtcgacc acccggacgt
    25501 cgaggccttc atcgagacca aggtgaagga ggaggagaag atccgcgccc tgcgcgacgc
    25561 gggcttcgac atggacctgg gcggcgacga catcacgtcc gtccagtacc agaacgccaa
    25621 caacagcgtc cgcgtgaacg acgagttcat gaaggccgtc gagtccggct cgaagttcgg
    25681 cctgcgcgcc cggatgaccg gcgagatcat cgaagaggtc gacgccaagt cccttttcac
    25741 caagatggcc gaagccgcct gggcctgcgc cgaccccggc atccagtacg acgacaccat
    25801 caaccactgg cacacctcgc cggagacggg ccgcatcacc gcctccaacc cgtgcagcga
    25861 gtacatgcac ctggacaact cgtcctgcaa cctcgcgtcg ctgaacctca tgaagttcct
    25921 gcgtgacgac gacaagggca accagtcgtt cgacgcggac cgcttcgcga aggtcgtcga
    25981 gctggtcatc accgcgatgg acatctccat ctgcttcgcc gacttcccca ccgagaagat
    26041 cggcgagacc acccgcgcct tccgccagct cggcatcggc tacgccaacc tcggcgccct
    26101 gctgatggcc accggccacg cgtacgacag cgacggcggc cgcgcgctcg ccggcgccat
    26161 cacctcgctg atgaccggca cctcgtacaa gcgctccgcc gagctcgccg cggtcgtcgg
    26221 cccgtacgac ggctacgccc gcaacgcgga cgcccacaag cgcgtcatga agcagcactc
    26281 ggacgccaac gcggtggcca agcgcaccga cgacctggac gtcccggtct gggccgcggc
    26341 caccgaggcc tggcaggacg tgctccgcct cggcgagaag aacggcttcc gcaacgcgca
    26401 ggcctccgtg ctcgcgccga ccggcaccat cggcctgatg atggactgcg acaccacggg
    26461 cgtcgagccc gacctggcgc tcgtcaagtt caagaagctc gtcggcggcg gctccatgca
    26521 gatcgtcaac ggcacggtcc cgcaggcgct gcgccgcctc ggctaccagc cggagcaggt
    26581 cgacgcgatc gtggcccaca tcgccgagca cggcaacgtg gtcgacgccc cggcgctgaa
    26641 gaccgagcac tactcggtct tcgactgcgc catgggcgag cggtcgatct cggccatggg
    26701 ccacgtgcgc atgatggcgg cggcccagcc gttcctgtcc ggcgcgatca gcaagacggt
    26761 caacgtgccc gagacggcca ccgtcgagca gatcgaagag gtctactacg agggctggaa
    26821 gctcggcctg aaggcgctcg cgatctaccg cgacaactgc aaggtcggcc agccgctctc
    26881 cgcgaagaag aaggagccgg ccgccgaggc cgtcgtcccg gccgaggtcc agaaggtcgt
    26941 cgagtaccgc ccggtccgca agcgcctccc gaagggccgt ccggggatca ccacctcgtt
    27001 caccgtcggc ggcgccgagg gctacatgac cgccaactcc tacccggacg acggtctcgg
    27061 tgaggtcttc ctcaagatgt ccaagcaggg ttcgaccctc gcgggcatga tggacgcctt
    27121 ctccatcgcg gtgtcggtgg gcatgcagta cggcgtgccg ctggagacct acgtctcgaa
    27181 gttcaccaac atgcgcttcg agccggccgg tctgaccgac gacccggacg tgcggatggc
    27241 gcagtcgatc gtcgactaca tcttccgccg cctggcgctg gacttcctgc ccttcgagac
    27301 ccgctccgcg ctcggcatcc actcggccgg cgagcgtcag cgccacctgg acaccggttc
    27361 ctacgagccg ggcgacgacg atgtggacgt cgagggcctg gcccagtccg caccgcgcca
    27421 ggtcgaggct cccgccccga aggccgcggc accgaagccg gtcgccgtcg ccaagccgga
    27481 gaacccggcc gccgtgccgg ccccgaagca ggcgcacaac tccacggagc tgctggagat
    27541 ccagctcggc ctgaacgccg acgccccgct ctgcttctcc tgcggcacga agatgcgccg
    27601 tgcgggcagc tgctacctgt gcgagggctg cggctcgacc agcggctgca gctgatcgtg
    27661 cgcgcgccgc gggagtgaac cgcggttgag ggagtgagag gtccggtgcc gacgggagtc
    27721 ggcaccggac ctttttccgt gccgggaata ggtgtgatct tgaaggactt gtgatcggtg
    27781 acgacacggg ggcggtgtcg cgggcggggt gcccgtacgg tgtgctgccg ccgtttccgc
    27841 tgatgacagg gggtagttgc gatgaccgag ctggatatcc attacgtggg cgggccgacc
    27901 gcggtgatcg tgatcggggg tctgcggctg ctcaccgacc cgacgttcga cgcgccgggg
    27961 gagtacccga tgggcaaccg ggcgctggtg aagaccaccg gccccgcggt cgatgcggac
    28021 gcggtcgggg ccgtcgacgc cgtactgctc tcgcacgacc agcacccgga caacctcgac
    28081 acctcggggc gggcgtatct ggcgagtgcg ccgctgacgt tgtccaccgg ttcggcgctg
    28141 gggcggatcg gcggaaacgt caccgcactg ccgaactggg agcacaccga gctgacccgc
    28201 ccggacgggg gaacgctgcg tatcaccggg gtgccggcgc agcacgggcc ggacggcagt
    28261 gagcccgtcg tcggcgaggt caccggattc gttctctcgg gcgagggcct cccgacggtc
    28321 tatgtgagcg gggacaacgc gtcgctgcag gtcgtacggg agatcgctga gcggttcgga
    28381 ccgttcgacg tcgcggtgct gttcgccggc gccgcgcaga ccccgctgct tccgggcgcc
    28441 gatctgacgc tcggcagcgt ccacgccgcc gaggcggcgg agatcctcgg cgcgcggcag
    28501 gtcgtaccgc tgcacttcga gcactggggg cacttcacac agaacggcga caccctggtg
    28561 gacgccttcg agcgggcggg gatcagcgac cgcctgcatc tgctgaagcc cggtgagcgc
    28621 ttcgagtccg ggaccgcgcg atgacggcga ccccggcggg gccggtggcg gagcgggaga
    28681 cagcggccgg atccgtcgcg gagtccgtct ggagcggtga ccggctcgac ctggacgcct
    28741 atctggcgcg gaccgggtac acgggcggcc tcgagcggac ggcggagacc ctgcggggac
    28801 tccaccgcgc gcacaccgcc gcgatcccgt tcgagaacct ggaggtcgcg ctggagcgcg
    28861 aggtccgcct cgacctggac agtgtgcagc gcaaactcgt cacggagcgc cgtggcggct
    28921 actgctacga acagaactcc ctcttcgcgg ccgtgctcga acgcctgggc ttcgtcttca
    28981 cggcccacgg cgcccgggtc cgcaccgccg gcccgacgct gcggcccatc acgcacgtcc
    29041 tgctgcgggt cgtcgtggac ggcgcggaat ggatctcgga caccggcttc ggcggtccgg
    29101 gaaccctgga gccggtcgag ctgcgggtcg gcaccccggc gtggcagggc ggctgggcct
    29161 tcgaggtcgc cgaggaagcg ggcggcgtgc gcgtgctgcg ctcgctcggc gcgcggggct
    29221 ggtcggacct gtacgcgttc gcgcccagcc cgctgtaccc ggtggatctc gtcgtcctga
    29281 atcactacac gtcgacgcac ccgctgtccc ggttcaccgg ccaggcagtg gtgcagcggg
    29341 tgacgccgca ggcgcggtac tccctggtgc gggacgagct gacggtgacg cgcgcgggtg
    29401 ccgcggacgg cgcggaggag cggcggaagg tgccggccgg ggagctgccc gaggtgctgg
    29461 agagcacctt cggcctcgtc ctcgccgcgg ccgacaccga acggctgggc cgtctgcacg
    29521 atccggcccg gtagggaggt gcggtcggtc gtgggacggg gtccggctca gtaggactgc
    29581 aactcgacga gggttccgtc cggcgtgcgc aggtgcgccg tacggaggcc gggtccccag
    29641 gccggccggt cctggggacc cgtgacgacc ttggcgccgt gcgcggtgag gagcggggcg
    29701 gcgtcgtcca cgctgtccac ccggaagacg agcatcgagg tgtcctgccc ggcgggccgg
    29761 gccggcaggg cctgggtgcc gaccaccgcc gcgacggcgg cacgggagaa caggacgagg
    29821 acgccctcgc cgttcaggtc ccagttggcg tatccggctt cggggatgac cttcacgggc
    29881 tcgatgccca ggaggtcgcg gagcgccgcg gtccagaatt cggcggcggt ggcgaagtcc
    29941 tccacgagga ggcggggatg aagtgcgtcc attgatcgat catattcgcc accccggcag
    30001 gggaattgag cgggtgagcg ggcgcgggag gggccctcgt cggacttagg atggcgcggt
    30061 gctggtgaag tggattcgct gtggggtcgt ggaccgggcg gggttcgaac gggggcagcg
    30121 gaagtgggcg gggctgcggg ggcagccagg attccggggg cagggcggcg gctggagccg
    30181 cgcgcagccg ggtgtggcgc atctgttcgc gttctgggac agcagggcgg cctacgacgc
    30241 cttcatgacg ggcgggcacg accagctcgc cggatcgcag gccgactcgt acgagaacct
    30301 cggggtgctg ctcttcgagc acctgctgga cgtgcgggtg ggcttcgagg cgcgcttcgc
    30361 cgacgccgat ctgctgcgtg tcgcgcattc gaaggtgcgg cccggacgcg gcgagcactt
    30421 cgccgagatg cagaagaagg tgtggaaccc ggcgatggcc gggtcgccag gactgctgcg
    30481 cggggccttc gccgaggggc cggacagcga cttcctggtg ctgtccctgt ggatctcggc
    30541 gaacgagcgc ggcaagtacc gccccgccgc gatgacgagg ctggcggagc gcaccgagct
    30601 ggagaccgat gtggtctcgg tggcgggcga cgtcgtggac atcgtgcagg cgtggacggt
    30661 gtgacggggt cgcgggcggc cgggagcgtc gaggccatga gggaccgggt caccatgggg
    30721 agccgggtca cggggagccg ggcggccgca gaggccgtac cggcgcgccc gggatccgtc
    30781 gcgggaatag gctgatcacc atgggccgac ctcgccacat cgtgctgatc cggcacggag
    30841 agtctcaggg caatgcggac gacaccatct acgagagggt gccggaccac gctcttgagc
    30901 tcaccgcgac cggccgtcgg caggccgcgg acgcggggga gaacctgcgg gcgctgttcg
    30961 gcgacgagcc ggtccaggcg ttcgtgtcgc cctaccgccg cacctggcag accttccgcg
    31021 ggctggacct cgacccgtcg ctgacccacg cgatggagga gccccggctc cgggagcagg
    31081 actggggtaa ctggcaggac gtcgacgacg tgcagcgcca gcgcaaggcc cgggacgcct
    31141 acgggcactt cttctaccgc ttcgcgcagg gcgagtccgg tgccgatgtg tacgaccggg
    31201 tgggtgcgtt cctggagacc ctctaccggg ccttcgacaa gccggacttc ccgccgaacg
    31261 tcctgctggt cacgcatgga ctgaccatgc ggctgttctg catgcggtgg ttccactgga
    31321 cggtcgagga gttcgagtcg ctgtccaacc cgggcaacgc cgagagccgc gtcctgctca
    31381 tcggaccctc gggccgctac accctcgacc gccccttcgc gcggtggcgg cttcccgacc
    31441 ccatggtgga cgaaggattc cgcaggtgag tttgcgcaca gggtgattga ccgggatcag
    31501 gcacgatgtc agagtttccg acgcgatgac cgctcaccca gttgactccg aaaacatctc
    31561 ccgcgccctg gcaagtctgc gcgggctcgc cgtcggcgac gccctcggct cccagttctt
    31621 cgtcccttcc aactaccagg ccctccagaa cggcgggctg ccgcccggcg tctggcagtg
    31681 gaccgacgac accgagatgg cctgctccgt gctggccgtg ctggccgccc acggccgcat
    31741 cgaccaggac gccctggcga tgtccttcgc ggagcaccat gacttcgacc gcggctacgg
    31801 cccggccgtg aaccgcatgc tgcgcctgat ccggcaggag ggcgccgact ggcgtgagct
    31861 ggccgcgggc ctgttcaacg gccagggctc gtggggcaac ggcgccgcca tgcgggtcgc
    31921 cccgctgggc gcctggtacg cgggcgacgc cgagcaggcg acacaccagg ccgagatctc
    31981 ggcgtacacc acccaccagc accgtgaggc cgtggtcggc gcgatggccg tcgcggccat
    32041 ggcggcgctg gtcgccgacc cggacggccc gaaggacccc tcggcgctgc tcggcgccgt
    32101 gctggacctg gtgccgacca gcgcggtgaa ggccggcata cggcgggcgc gcgacatgct
    32161 cgactacgcg gacgtggcca cggtggcagc ggtgctcggc tgtggccggc gcaccagcgc
    32221 gcacgacacc gtgccgttcg cgctgtggtc ggcggcccgg cacctggacg actatcagca
    32281 ggcgttctgg acgacggcca aggcgggcgg tgacgtcgac accacctgcg cgatcgtcgg
    32341 cgggatcatc gccgcacggc cgaccgggca gccgccggcc gggtggctgg agcgcaccga
    32401 gccgctgccg ctgtgggtgg cggcgcccgc ggaggcctga gcccggacgt acccgggccg
    32461 gtcccctccc tggccatctc cgctccgccg ctcggccccg ttcaccgggc cgggcggcgg
    32521 agcggtgtca ggccgccggc gcggcggatt tcccgctgag cgcttccagg tcgctcttgc
    32581 gcacccgcac cacgaacagc gcggtgagta ccgccagcac gacgaagccg acgcccgcca
    32641 tgaaggccgt ggatatcccc tgggagagca cgtcgtgccc ccagggggcg ggcagctcat
    32701 gggtccgcgc ga
//
