LOCUS       NZ_CP048835            32876 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3633932
            Orig. end                         :: 3666808
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..32876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="12"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..32876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..32876
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:18876](+)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..18876
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    949..960
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     gene            1489..1986
                     /locus_tag="C8250_RS16475"
                     /old_locus_tag="C8250_016500"
     CDS             1489..1986
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143110.1"
                     /locus_tag="C8250_RS16475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016500"
                     /product="OsmC family protein"
                     /protein_id="WP_138353235.1"
                     /transl_table=11
                     /translation="MPTPHTYDTQVTWTGNLGTGTSTYRAYDRSHEVSAAGVPTILGSS
                     DPTFRGDASRWNPEQLLLAALSQCHMLAYLHVCAVGGVTVTAYTDNAHGTMETTPEGGH
                     FTEAVLRPQVEVASQEMADKAATLHADAHRTCFIAASVNFPVRHEPVITVSSLAPRGNR
                     SA"
     gene            complement(2060..2965)
                     /locus_tag="C8250_RS16480"
                     /old_locus_tag="C8250_016505"
     CDS             complement(2060..2965)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545516.1"
                     /locus_tag="C8250_RS16480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016505"
                     /product="DJ-1/PfpI family protein"
                     /protein_id="WP_138353234.1"
                     /transl_table=11
                     /translation="MTRVVFLLVPHLHLLDLAGPAQVFSTAADFGYDYETAYVGEQEDI
                     PTAQGVPLRAATRWPDLTPDDLAIVPGWRSRTLRQNGHVAESTLQRLRDHHAAGGVVAS
                     ICAGADALGRAGLLDGRRCTTHHDVQDELAVRHPRATVVRDVLYVVDDRIVTSAGIASG
                     IDLALHLVAGRHGPGAAARIARNMVVYARRNGDEQQTSAMLRHRAHLSDAVHRVQDLID
                     ARFTEHLGLADLAATSGVSERTLTRRFGEATGLTPLRYQQVLRVERAVHLISHGSTIES
                     AARAVGFEDARMLRRLRARA"
     gene            complement(2962..3546)
                     /locus_tag="C8250_RS16485"
                     /old_locus_tag="C8250_016510"
     CDS             complement(2962..3546)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004955356.1"
                     /locus_tag="C8250_RS16485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016510"
                     /product="isochorismatase family protein"
                     /protein_id="WP_138353233.1"
                     /transl_table=11
                     /translation="MNRALIVIDVQQSFLQRPLWQASSNPGIVGQVNRLVAHARDEGDL
                     VVWVLHSEPGTGGVFDPASGHVRLMEGLEPLDGEPVLTKTAHNAFTTTNLQQLLTSRGV
                     TEVITSGIRTEQCVETTTRLASDLGYEVTFVTDATATTPCEHWDAPAGRSVEEILADPR
                     TLQTDDIIARTEYALAGRFARVTTVKELTGS"
     gene            complement(3623..4069)
                     /locus_tag="C8250_RS16490"
                     /old_locus_tag="C8250_016515"
     CDS             complement(3623..4069)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126769.1"
                     /locus_tag="C8250_RS16490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016515"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_232484976.1"
                     /transl_table=11
                     /translation="MAAPDDSPGFLFWRTSLHWQRAIAAALAPLDLTHAQFVLLAGLWW
                     LDSQGEQPNQLQLARHSGTDVKMTSQVLRRLEDKGLLTRVTDPSDTRAKRLGITPAGAE
                     LATEAVATVEATDAAFFGAAPDQEALLAALRTLALPPAGPPADA"
     gene            4310..5641
                     /locus_tag="C8250_RS16495"
                     /old_locus_tag="C8250_016520"
     CDS             4310..5641
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005317988.1"
                     /locus_tag="C8250_RS16495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016520"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_187144871.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-55, bitscore:
                     187.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIEAGTEIVVVGGGMAGARLAQQLAPAAPGVRVTLFGEEAHAPY
                     NRVLLAEVLAGRYEPDVITLPDAACTVRRVVRVDRAERLVICDDGSATRYDRLVLATGS
                     NPVLPPLRGLFEAGRGELPLGVHAFRTMDDCLALSGALHPGVRAVVVGGGLLGVSAARA
                     LAARGAHVVLLQQGEYLMERQLDEQSGRLLRTHLESMGIEVHTECRVRGLRTAPDGTPQ
                     AVRAVRSVELADGYCLGTDLVVLACGVRPRTGLAQAAGLEVDRGIVVDDELRTSDPFIH
                     AIGDCSQHGGVVYGLANAAREQADALALLLTEAARGPAPGRPADPPRYTGTRALTRLTL
                     GGSPAPAANASEPARTGATGIAPFDLAAFGDPLPVPGDDVLRLTDATRGAYRKVVIRDD
                     RLVGGILLGDLAAVGTLARTWEADEPLPASSAPLLHLLTNDGGS"
     gene            5644..8265
                     /gene="nirB"
                     /locus_tag="C8250_RS16500"
                     /old_locus_tag="C8250_016525"
     CDS             5644..8265
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0042128 - nitrate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nirB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608357.1"
                     /locus_tag="C8250_RS16500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016525"
                     /product="nitrite reductase large subunit NirB"
                     /protein_id="WP_232484975.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-48, bitscore:
                     163.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.3e-11, bitscore:
                     43.6, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVDTMAGGTTDVPTVPTIVLVGHGMVGQRFLEALADRGVTERAR
                     VVVLCEEPRAAYDRVHLTSYFSGTTPDGLALAEDGFMEKHGIELRLGDPALTVDRAART
                     VTARSGLTFGYDTLVLATGSFPFVPPVPGKDTEGCFVYRTIEDLLAIEEYAATGGTGTV
                     VGGGLLGLEAAGALKGLGLDTHVVEFAPRLMPVQIDEGGGEALRRTIEEMGVTVHTGVG
                     TQAIVAGEDGRVAAMSLSDGSTLTTGLVVFSAGVRPRDQLARECGLPVGERGGIVVDEQ
                     CRTEDEAVYAIGECALASDGRVYGLVAPGYEMAETAAKAIAGDAGSFKGADLSTKLKLL
                     GVDVASFGDAHGATPGCLDVLYSDSRSGVYKKLVVSREGVLLGGILVGDADSYGMLRPM
                     TGSVPPVPPERLVLPAGAGGPVELGPSSLPDTAVICSCHNVTKGAILGAVTEHSCTTVP
                     QLKKCTKAGTGCGSCLKVLGQLLPPAEDKGLCGCFAHTRQELYEIVRALRVTSFAALLD
                     SHGREAARGGEGCEVCKPAVASVIASLAPSIGAPVHVLDGGQAALQDTNDHFLANLQRN
                     GSYSIVPRIPGGEITPEKLIVIGEVARDFGLYTKITGGQRIDLFGARVDQLPLIWTRLV
                     DAGFESGHAYGKALRTVKSCVGSTWCRYGVQDSVKMAIGLELRYRGLRSPHKLKSAVSG
                     CARECAEARGKDFGIIATASGWNLYVGGNGGADPRHADLLAQDLSDAELVRLIDRFLMF
                     YIRTADRLERTSAWLERIEGGLEHVRDVVVHDSLGICDELESLMSAHVAGYRDEWADTI
                     NDPERLSRFVSFVNAPDVPDPSVRFVEERDQVKPDLDLLAGPVLLAGPTLAIRTLEGTV
                     TA"
     gene            8262..8585
                     /gene="nirD"
                     /locus_tag="C8250_RS16505"
                     /old_locus_tag="C8250_016530"
     CDS             8262..8585
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nirD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009718083.1"
                     /locus_tag="C8250_RS16505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016530"
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="WP_138353231.1"
                     /transl_table=11
                     /translation="MTIELLLDDAWFPVCDDALLTPGRGVAALLPDGSQAALFQDRHGA
                     LYAIGNRDPFTGAYVLSRGLLGSAAGRAYVASPLLKQRFDLATGTCLDDESVSTASYAV
                     RSQ"
     misc_feature    8640..8658
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 25.73"
                     /tool="antismash"
     misc_feature    complement(8645..8663)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.44"
                     /tool="antismash"
     gene            8730..9698
                     /locus_tag="C8250_RS16510"
                     /old_locus_tag="C8250_016535"
     CDS             8730..9698
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321350.1"
                     /locus_tag="C8250_RS16510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016535"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_187145288.1"
                     /transl_table=11
                     /translation="MPLFLLGAVALTACAAASLALGSRPVPLGTVLDALFHHAHSRDAV
                     VVTGLRVPRTLIGLAVGAALGVAGAVAQGVTRNPLASPTTLGINAGAGFAVVTAIYALH
                     LTHPSQYLWFAFAGAAAAALFAQTLARRAGDLDPVRLALGGTVLTAVLVSWTSAVMLAS
                     NRTLDEARFWLAGSLSGRTLDVLYPVLPLIAVGLVIALAITPALNALALGDETAQALGV
                     PVARIRVAGGLSVVLLAGSAVAVAGPVAFIGLAAPHLVRLVFGNDHRLLVPGCLIAGPL
                     LLLGADVLGRVMIAPSELEVGIVTAFLGAPLLAVLARKVAR"
     gene            9695..10825
                     /locus_tag="C8250_RS16515"
                     /old_locus_tag="C8250_016540"
     CDS             9695..10825
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090702.1"
                     /locus_tag="C8250_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016540"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_138353229.1"
                     /transl_table=11
                     /translation="MTPPAPTTPPTPVTPPAPTTTQSLVPAPRKDAKDASAAPKRRPSR
                     GRRTALLSVCAVAAILVLATTALTTGQILMPPLTALRALIGLGDSGDVLVVQEFRAPRM
                     AAAIVAGAGLAVAGGLLQRLFRNPLASPDVMGVTGGASLGAVSLLATGASQTLIPLAAL
                     GGGLLAAVLLGAFAWRSGLGVTRLVLVGLAVQAGLAAAVNLMVVRFPAELANSALQWTT
                     GSLYGRTWTEVSAAGGAVAAAMAAAFVLHRRLAVLDLGDDSAGGLGLAPSAARLQLLLT
                     AIVLASLAAALTGPVAFVALAVPHVVRFLAGPPTAGTLALSALTGAVLLLGSDLVVQHL
                     LPVHGLPVGVVTATLGAPWLLVLMIRQSRPTHRSFG"
     gene            10822..11661
                     /locus_tag="C8250_RS16520"
                     /old_locus_tag="C8250_016545"
     CDS             10822..11661
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373680.1"
                     /locus_tag="C8250_RS16520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016545"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138353228.1"
                     /transl_table=11
                     /translation="MTARADRPNRTNQLSTHGLDLRYGDRLVIGGLDLVLPGGAVTAIV
                     GPNACGKSTLLRGLSRLLSPAAGTVALDGADIHRMPARSLARRMGLLPQQPVTPEAITV
                     EALVRLGRYPHQRLLSPWSATDQAAVDEALERTGTTELRDQHVDQLSGGQRQRAWIALA
                     LAQDTELLLLDEPTTFLDLRHQLDVLDLVSDLHTESGRTVVMVLHDLGQAARYADHLVV
                     LQEGRPAAAGPPSEVLDAALVKAVFDVDCQVIPDPETGTPLVVPRGRARRHATAVAG"
     gene            11724..12731
                     /locus_tag="C8250_RS16525"
                     /old_locus_tag="C8250_016550"
     CDS             11724..12731
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607216.1"
                     /locus_tag="C8250_RS16525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016550"
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_138353227.1"
                     /transl_table=11
                     /translation="MNTRAPLHRRLVRLIAAPVALVIGVGALAACGSGTAAKDDKANAA
                     ATADGFPRTITHAMGSTTIPAKPQRVVVLDTGELDDVTMLGITPVGAVAPHLKSEGGFP
                     AYLQGRTEGTKDVGPSAEPDLELIASLKPDLILSSKVRHEKVYDKLKAIAPTVFTATTG
                     FPWKENLAVHAKALGLEKEAATALKSYEDRAKKLGAAIKSRNGGKEPTASVVRFVAGPT
                     RLYQLDSFSGVVLSDIGLGRPASQNVHSAMLEVGPEQIDKADADLVFVTVSDDPAKTRQ
                     SVVESNPVWKDLGAVRNHKVVNVTDETWMSGIGVQAALSMLGDVAKAAGVDLPE"
     misc_feature    complement(12793..12807)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.06"
                     /tool="antismash"
     gene            12811..14004
                     /locus_tag="C8250_RS16530"
                     /old_locus_tag="C8250_016555"
     CDS             12811..14004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852068.1"
                     /locus_tag="C8250_RS16530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016555"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_138353226.1"
                     /transl_table=11
                     /translation="MRLYLLALNPTDSVTEGFLPAASRLGLDVTVLTDSPAAHQELYGT
                     QVDVEECDVRDFRAVITRIATGRTPHAVFTNSDHLQTQTALAAEYFGLPAKPWQAALRT
                     KDKAQMRRHLAATGADTVWSAELAAGADPASLLGLPVPYPCVVKPREGVASEDVVLVGG
                     PEELVLRCKEIQARRPQAALVAEEYLTGELYTLETLGDGRTRHVLGGFHTGLSPLPYFI
                     EERLTFVPEHPAAVVEQILAQLDALGVGFGACHTEFVVQDGRARIIEVNYRAIGDQCDL
                     LLAGLLDIPLFEHILRVHLGEPLPADLGARGGGRARLEYPCADRAGTLTAAPEATERTV
                     DGVRLVYRPLRATGERHELHHTNRDLLGIVRATGTDQEAVDRVVTDFLRAQRWEITP"
     gene            14001..15800
                     /locus_tag="C8250_RS16535"
                     /old_locus_tag="C8250_016560"
     CDS             14001..15800
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373685.1"
                     /locus_tag="C8250_RS16535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016560"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_138353225.1"
                     /sec_met_domain="IucA_IucC (E-value: 7.7e-34, bitscore:
                     116.2, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTRTTDAGVDAELMLRVLSALLREDVVGLRTRSTLVEESDGRW
                     LRLPYTYGGDGAGGFGKALLLPVTDDGFQSEYAARLPLLRRASDGRELTGADAVLRALR
                     ALADPVDQAGFDAFAEECRQTAATLRLHDRVRAEVTGRLAERYGSDTAYWTYARSLGFD
                     ALAAFHDHPVYPTSRGRSGLGESDLRAYAPEFHEDVAPRWLVLPRDAVTESGGGPAETY
                     AYLWPTPASLGMPELRDTHTVLPVHPLTVGTPLDEALRATGLEGRAFLAEQAPLSLVPT
                     LSMRTLADRTYPLLHLKLPLATATLGLRNRRTIKPGTLADGAACQLLLSEVIAREPRFQ
                     DTVLLADERRYAHAGHELLAVLLRRYPEHLQNSVLVPIAALLAGAPDGRLVIDQLADRF
                     YDGDPIALLDACLTLLFDWQTTLFGYGIALESHQQNISLALDQDRTTGTTRLRLVLKDN
                     DGPRINTARLSRALGELTARIDEFDDERIFCVSDEPLIDLFTTITVHLCAGSYAFGLAD
                     HGRAPLDDLLRLVRDRLSEAFDRLGGEPAELLRERVLNAERLPVKAMVSAGTLLSKERS
                     GAADINKHYTTGPNYLLVGTGSR"
     gene            15797..17035
                     /locus_tag="C8250_RS16540"
                     /old_locus_tag="C8250_016565"
     CDS             15797..17035
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373693.1"
                     /locus_tag="C8250_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016565"
                     /product="MFS transporter"
                     /protein_id="WP_138353224.1"
                     /transl_table=11
                     /translation="MSAEAATISAAPAPALGRRQVHAVAACYFVASFAALGLPPYLTSI
                     LPELGDPTAHWAGLLYIVPTVFGGLAAPLWGRLADRYGRKRLLLRAQFGLALSFLLAGA
                     ADSLPTFTAALVLQGILGGTFAATNGYLAAGLDGTRLSWALTLMQGSARAALVAAPIVV
                     GTLSPWLSPHRQYALLALLPLGAAAMLLALPEPRETVVVMEKPRAEQQMLGAEPVEIAV
                     VAPPVTAQRGLLRELYLFEFAFVFSTVISFPYLIALLGDRISGISPVVSGSLFALPHLC
                     YLLFAAPVHSAFRNRPRLGIALGFTAVTAGLAGHAVAGSLITFTAVRLLLGAGLTLGLV
                     GLSLLAADAVQGRSPGRMFGSLEFVSKGGAVAAGVVAALGNSAFGPTAPVLAGTAVALI
                     TVAAAVHALFSHP"
     gene            17047..18876
                     /locus_tag="C8250_RS16545"
                     /old_locus_tag="C8250_016570"
     CDS             17047..18876
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891024.1"
                     /locus_tag="C8250_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016570"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_138353223.1"
                     /sec_met_domain="IucA_IucC (E-value: 3.1e-55, bitscore:
                     186.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPLHLAQPSAGLSASALSASGLHASGLPDADDVVAHTLLNCLL
                     REVSGPEHQTAVADGHLLLRLPRADALLRVALRRTSLIGAHRFTGPVAEQHADGWKELD
                     WYRLAEYVHDELSLRTGVRNDEFLDQIVSSHRGVAAALSLPRPVPGSDDGPGAPDYLES
                     ERSLLFGHRFHPTPKARTGDPASWAAYAPEAGATFPLRHFAVREHLIAEERSEPGAADP
                     LDRLRPVPAGYRLLPAHPWQYGLLHDHPALRAALACGDILDLGTGDAAAAPTASVRTLY
                     DGDTFLKFSLNIRITNCLRKNAAYELSGAVALTRLLAPVLADLAGRFPDSAMLREPAYR
                     SLALPGADGRPDIGLLEGFGVIVRDGLAAHLRPGVTPLLAAAVADEYPTGSAHISRLLD
                     GAGPQAALDWWTAYLRLLLPPVLAAYFDHGVVLEPHLQNVLIGVDGDGFPVQVLFRDLE
                     GTKLLPEHHAATLAALPADVAAPMTYDAERGWDRVIYCLLVNHVAELLAALADLHPQSE
                     TALWARVHGVLREYADDHGCPPRLSALLAGVPLPAKANLLTRWERKADREAGYVRLPSP
                     LAEDVLSGASAPGAAGCGTGGDDSDRTEPWSTR"
     gene            18873..20105
                     /locus_tag="C8250_RS16550"
                     /old_locus_tag="C8250_016575"
     CDS             18873..20105
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607222.1"
                     /locus_tag="C8250_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016575"
                     /product="type III PLP-dependent enzyme"
                     /protein_id="WP_138353222.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 5.6e-30, bitscore:
                     103.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 3.4e-12,
                     bitscore: 45.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPNSSAGPALLTDAVRDRATYLAADDLPAYLYDLAELRAHAAAV
                     RAALPERVELYYAAKANPEPEILTALAPYVDGFEVSSGGELTHVRKAVPDRPLAFGGPG
                     KTPAEIAAALELGVERFHVESEYELRMLGHLAARPAPGRTVPVLLRFNLPVPGAALEGS
                     SLAMGGCPTPFGLDPAQADSAVRLLTDGSHPQLELRGIHAHLASGLDATAQLAVAAEVV
                     AFAVGLAARHGIALPEVNVGGGMTVDYADPGARFDWTAYGEGLARLIAAHPGLLLRIEP
                     GRALSAYCGWYATEALDVKPSHGEEFAVLRGGTHHLRTPATKGHDQPCEVLPVGHWPHP
                     WPRPAAGQDHVTLTGQLCTPKDVLARRVPAPGLRAGDRVVFALAGAYAWNISHHDFLMH
                     PRPGFHFLGSA"
     gene            20114..20755
                     /locus_tag="C8250_RS16555"
                     /old_locus_tag="C8250_016580"
     CDS             20114..20755
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958184.1"
                     /locus_tag="C8250_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016580"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_138353221.1"
                     /transl_table=11
                     /translation="MTDHEVLRVFIGPDGRGGNLLGVVSADSSDPAARQAIAAELGYSE
                     TVFIDDAERGDVRIFTPSVELPFAGHPLTGTAWLLKSSLLRPPAGDVPAWTEGDFTWIR
                     GRAAWAPGRRTEQYPTVAEVDALPSPPPGEGWLYAWAWADEAAGRVRARGFPRRGDAIT
                     EDEATGASAIVLAAQLARPLDIRQGTASQILTRPGPDGTIDVGGRVAAVR"
     gene            20818..21588
                     /locus_tag="C8250_RS16560"
                     /old_locus_tag="C8250_016585"
     CDS             20818..21588
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (11-122). E-value: 7e-19.
                     Score: 60.3. Matches aSDomain:
                     nrpspksdomains_C8250_RS16560_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019073675.1"
                     /locus_tag="C8250_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016585"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_138353220.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-14, bitscore: 53.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.6e-15, bitscore:
                     54.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLSHDVAGDGPAVVLLHSGVCDRRMWDAQWTDLVDAGYRPVRCD
                     FRGFGRSPVPDRPYSNADDVLDLLDTLGIERAALVASSSGGRVALEIAARRPERVSALA
                     LLCSALPGHEVSAGLRAIGAREDELLEAGDVAGAVELMVDTWVGPAGGPDVREAVRGMQ
                     RRAFDVQLAALEEFEPIRAEFDLAAVTAPCLAVSGAHDVTDFREIAAALPGLLADARHV
                     ELPWAGHLPSLERPAAVTELLVGFLRGTVPAAGR"
     aSDomain        20851..21183
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS16560_Abhydrolase_1.1"
                     /evalue="7.00E-19"
                     /label="C8250_RS16560_Abhydrolase_1.1"
                     /locus_tag="C8250_RS16560"
                     /protein_end="122"
                     /protein_start="11"
                     /score="60.3"
                     /tool="antismash"
                     /translation="PAVVLLHSGVCDRRMWDAQWTDLVDAGYRPVRCDFRGFGRSPVPD
                     RPYSNADDVLDLLDTLGIERAALVASSSGGRVALEIAARRPERVSALALLCSALPGHEV
                     SAGLRAI"
     gene            21723..22637
                     /locus_tag="C8250_RS16565"
                     /old_locus_tag="C8250_016590"
     CDS             21723..22637
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556672.1"
                     /locus_tag="C8250_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016590"
                     /product="oxidoreductase"
                     /protein_id="WP_138353219.1"
                     /transl_table=11
                     /translation="MGWTANDIPDQTGRTAVVTGANSGIGYCAAKELARRGALVVLACR
                     SEERGQAAADRLVAEVPEARAVFQRLDLGDLGSVRAFAEEFAGDRLDLLVNNAGVMALP
                     YTQTADGFETQFGVNHLGHFALTGLLLPKLLATPGARVVSVSSGMHAIANVDLGDLNSE
                     RRYRRWIAYGRSKSANLLFIHELARQLGTTGADIVAAAAHPGYAETNLQTAGAKLEGRR
                     RAERVIGIGNRIIGQSAAAGALPTLYAATAPDVAPDSFTGPRLQGWRGAPSRSWRASWT
                     KDDRAGEMLWTASEQLTGVTYKF"
     gene            complement(22687..23499)
                     /locus_tag="C8250_RS16570"
                     /old_locus_tag="C8250_016595"
     CDS             complement(22687..23499)
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179: hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018889575.1"
                     /locus_tag="C8250_RS16570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016595"
                     /product="HAD family hydrolase"
                     /protein_id="WP_187144872.1"
                     /transl_table=11
                     /translation="MTASPSRTPPRLVATDLDGTLLRSDGTVSERTRRALRSVAAAGAE
                     VVFVTARPPRYVDGIAEGAGHEGTAICCNGAIVYDVPGRQFLDARLMPNPVARKAAEAL
                     VAVLPGSTLALETGHRLISERDFGKKDFQEVIVETAAELWESDEDIVKLLVHSSRHHAD
                     RMMTAAHDAALTGVEVTHSGGSGMLEISSPGVTKAGTLALWCAARGIGASEVVSFGDMP
                     NDLSTLTWAGAGYAMSNAHPDVLAAAPLRAATNDEDGVARVLEELYGG"
     gene            23712..24764
                     /locus_tag="C8250_RS16575"
                     /old_locus_tag="C8250_016600"
     CDS             23712..24764
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS16575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_016600"
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_138353218.1"
                     /transl_table=11
                     /translation="MGRHTRAILAGLGLAGLLLAAGPAAEAQADAGPVDADVQMQFLHP
                     QVAPGRQFHFYLLTHLKSGTLSTFRGLVHLPEGMTYVPVVERTCEPTSANKREIACRPD
                     SQSLTVQVADDVPVGTRLTITATADIGDAVDTHPEDNTARQEVLVKPGADWSVKWTGPT
                     TPVQPGSTPVTTRLVVTNHGQEADLPFILTSGPGDYPRQMEYYGKWDKTCGIATEGNGL
                     LCRPTTPVPPGGTITYTFRFKVYPAALGKEQRREARVSSEFPATEPDINDNTTTLVVKV
                     ADKAAQPTGKPTSPATGGAKPTSAPTTAPGDHLADTGGAGTGSALTAAGAAAAVGGGLL
                     LTSRRRRRSH"
     gene            complement(24842..27553)
                     /gene="ppdK"
                     /locus_tag="C8250_RS16580"
                     /old_locus_tag="C8250_016605"
     CDS             complement(24842..27553)
                     /EC_number="2.7.9.1"
                     /GO_function="GO:0050242 - pyruvate, phosphate dikinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015976 - carbon utilization [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ppdK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PPDK_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944998.1"
                     /locus_tag="C8250_RS16580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016605"
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="WP_138353217.1"
                     /sec_met_domain="PPDK_N (E-value: 3.1e-41, bitscore: 140.7,
                     seeds: 105, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEQVSQKFVYDFTEGNKELKDLLGGKGANLAEMTNLGLPVPPGF
                     VITTEACKVYLDSGHEPAELRDEVSAHLDALEQKMGKKLGQPDNPLLVSVRSGAKFSMP
                     GMMDTVLNIGMSDASVAGLAAQAGDERFAWDSYRRLLQMFGKTVMGVDGELFEEALEEI
                     KRAKGAESDLGLDAADLQQLVEEFKGIVLKETGREFPQEPREQMDLAVRAVFDSWNTDR
                     AKLYRRQERIPGDLGTAVNICSMVFGNLGPDSGTGVAFTRDPATGHQGVYGDYLQNAQG
                     EDVVAGIRNTVPLADLEGLDKASYDQLMQIMTTLETHYKDLCDIEFTIERGHLWMLQTR
                     VGKRTAAAAFRIATQLVDQGLIDEAEALQRVNGAQLAQLMFPRFEEDSKVTRLGWGIAA
                     SPGAAVGKAVFDSYTAVKWSRSGEKVILIRRETNPDDLNGMIAAEGILTSRGGKTSHAA
                     VVARGMGKTCVCGAEELEVDTKRRRMTAPGGIVIEEGDVVSIDGSSGKVYLGEVPVVPS
                     PVVEYFEGRMHAGADDADELVQAVHRIMAYADRVRRLRVRANADNAEDANRARRFGAQG
                     IGLCRTEHMFLGERRELVERLILADTDSERDEALGALLPLQKADFIELFEAMDGLPVTV
                     RLLDPPLHEFLPDITELSVRVALAESRKDANENDLRLLQAVHKLHEQNPMLGLRGVRLG
                     LVIPGLFSMQVRAIAEAAAHRKNMKGDPRPEIMIPLVGTVQELEIVREEAEKVIAEVEA
                     ATGINLKLTLGTMIELPRAALTAGQIAEAAEFFSFGTNDLTQTVWGFSRDDVEASFFTA
                     YLEKGIFGVSPFETIDRDGVGALIRSACEAGRAARPGLKLGVCGEHGGDPESVHFFHEV
                     GLDYVSCSPFRIPVARLEAGRAAADPSGNDSR"
     misc_feature    27785..27798
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.68"
                     /tool="antismash"
     misc_feature    27807..27821
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.09"
                     /tool="antismash"
     gene            complement(27994..29136)
                     /gene="dusB"
                     /locus_tag="C8250_RS16585"
                     /old_locus_tag="C8250_016610"
     CDS             complement(27994..29136)
                     /EC_number="1.3.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="dusB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556670.1"
                     /locus_tag="C8250_RS16585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016610"
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="WP_138353216.1"
                     /transl_table=11
                     /translation="MTADATMPLQIGPHTVWPPVVLAPMAGITNAPFRTLCREFSGGKG
                     LFVSEMITTRALVERDSKTLRLIRFDATEKPRSIQLYGVDPVTVGKAVRMIADEGLADH
                     IDLNFGCPVPKVTRKGGGSALPYKRNLLRSILREAVGNAGDLPVTIKMRKGIDDDHLTY
                     LDAGRIAVEEGVTAVALHGRTAAQHYGGTADWDAIARLKEHVPEIPVLGNGDIWRADDA
                     LRMMRETGADGVVVGRGCLGRPWIFGDLVSAMEGGDAQARPTFKEVAVVMRRHAELLGE
                     WIGDEERGVIDFRKHVAWYTKGFSVGSQLRRSLAVSSSLAELDEHLAAVDLDQPWPESA
                     EGPRGRTAGNNRVVLPDGWLNDPYDCAAVSPEAELDTSGG"
     gene            29241..30665
                     /locus_tag="C8250_RS16590"
                     /old_locus_tag="C8250_016615"
     CDS             29241..30665
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531004.1"
                     /locus_tag="C8250_RS16590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016615"
                     /product="MFS transporter"
                     /protein_id="WP_138353215.1"
                     /transl_table=11
                     /translation="MPELSPRRRMLVLAICCMSLLMVSLDNTILNVALPSLQKELHASV
                     SGLQWTIDAYTLVLASLLMLAGSTADRIGRRRVFQTGLVLFTAGSVLCSLAPSLNWLVV
                     FRMVQAVGGSMLNPVAMSIITNTFTDPRERARAIGVWGGVVGVSMAAGPVLGGLLVQTV
                     GWRSIFWINLPVGLLALALTARYVPESRAPKPRRVDPVGQLFVIALLGSLTYAIIEAPD
                     AGWTSALILGCLAVAIGSLAGLLSYERRRVDPLIELGFFRSAPFSGATVIAVSAFAALG
                     GFLFLNTLYLQNTRGLSALDAGLYMLPMAVMCLVFAPLSGRLVGNRGPRLSLVLAGTAM
                     TISGVMFAALDAESSNTLLFTSYVLFGIGFGLVNAPITNTAVSGMPRSQAGVAAAVAST
                     SRQVGQSLGVAVIGAAIAAGLHTTAWWIIAGCGAVVLLLGTLTTGRWAAGTAERAAARF
                     REPAPLTVGTEAVTNS"
     gene            complement(30666..31577)
                     /locus_tag="C8250_RS16595"
                     /old_locus_tag="C8250_016620"
     CDS             complement(30666..31577)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008742989.1"
                     /locus_tag="C8250_RS16595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_016620"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_138353214.1"
                     /transl_table=11
                     /translation="MPTTTPPAQHESDADIKRRELASFLRSRRERIAPEQVGLPAGRRR
                     RTPGLRREEVAGLAAVGVTWYTWLEQARDIQVSAQVADAIARALMLDPNERVHLFTLAG
                     VADPSPFADCPGMSDQIRLMLEQLEPLPAFVANSRHDVIAYNRTYGRLVDDLDARPFED
                     RNIMWLAFTDPAWREALIDREEVIRLMAAKFRSAMAEHLAEPAWKSLLKRLQQASPEFC
                     EAWDRHEVLQPDNRSKRYLNPQVGLLTFDFTHLWLGPRSGPRLVTYTPADEVTRTRLQR
                     LYELCGPAASDARPVLASAGRS"
     misc_feature    31863..31883
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.45"
                     /tool="antismash"
     misc_feature    complement(32023..32032)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 cggcaccgat ctggcgctcg cgctcgggct gctgcacctc gccgtcgccg agggacatct
       61 ggacgagcgg ttcatcgcgg agcgcacgac cggctgggcc gaggcgcggc caggcgtcat
      121 ggcgcactgg ccggaactgg tggaacgcat caccggggtg ccggtgccgc aactccggga
      181 ggccgtgcgg atgttctgcg cgacaccgga gagcatggtg ctcaccgcgc gcggccccga
      241 gcagcagtcc aagggcaccg acaccgtcag cgcctggatc aacctgtgcc tcgcgaccgg
      301 ccgcgcgggc cggccgctct ccggctacgg ctgcctcacc gggcagggca acgggcaggg
      361 cgggcgcgag cacggccaga aggccgacca gctccccggc taccgcaagc tggacgaccc
      421 gggcgcacgg gcgcacgtgg cggcggtgtg gggtgtcgac ccggacgacc tgccggcgcc
      481 ggggcgcagc gcgtacgaac tgctggacac gctcggcgtg gaggtgcacg cgctgctgct
      541 gatgggctcc aacccggtcg tctccgcgcc gaacgccgcg cacatcaccg aacggatcgc
      601 ctcgctcggc ttcctcgcgg tctgcgacgt cgtcctgtcg gagacggccg agctggcgga
      661 cgtcgtgctg ccggtcaccc agtgggcgga ggagaccggc acgaccacca acctggaagg
      721 cagggtcatc ctgcgccgca aggcgatcga cccgccgccg gaggtccgta ccgacctgga
      781 ggtgctgaac gggctcgccg cccggctcgg gtgggagaag ggcttcccca ccgaccccga
      841 ggaggtcttc gacgagctgc gccgcgcgtc ggcgggcggt ccggcggact actcgggcat
      901 cacctaccgg cggatcgcgg aggaggacgg cgtcttctgg ccgtgcccgc aaacgtcttc
      961 ggacgccgcg caccccggaa cgccccgcct cttcctggac cgtttcgcga cgccggacgg
     1021 cagggcccgc ttcgtcccgg tcctgcaccg gccctccgcg gaggagccgt cggccgacta
     1081 cccgctccat ctgacgaccg gccgcgtcct ggcgcagtac cagtccggtg cccagacccg
     1141 ccgtgtcccc gaactcaacg ccgcctcccc cggccccttc gtgcagctcc atccacagct
     1201 cgccgcgcgc ctgggggtcg ccgagggcga cgtcctcgcg gtcaccagcc gccggggccg
     1261 cgccgtcgcc cccgcgctca tcagctccgc catccgcccc gacaccgtct tcatgccgtt
     1321 ccactggccg ggcgagggcc gcgccaacac cctgaccaac ccggctctcg acccgacgtc
     1381 ccgcatgccg gagttcaagg tgtgcgcggt gcgggtggag gcggtgggtc ccgcgaccgg
     1441 ctgaacgtac tctgggccct gtccggcaga tcaacagaag gagccgccgt gcccacgccc
     1501 cacacctatg acacgcaggt cacctggacc ggcaacctcg gtaccgggac gagcacttac
     1561 cgcgcctacg accgttccca cgaggtctcg gccgccggcg tacccaccat cctcggcagc
     1621 tccgacccga ccttccgcgg cgacgcctcc cgctggaacc ccgagcagct gctcctcgcc
     1681 gcgctgtcgc agtgccacat gctcgcctac ctgcacgtct gcgccgtcgg cggcgtcacc
     1741 gtcaccgcct acacggacaa cgcgcacggc acgatggaaa ccacccccga gggcggccac
     1801 ttcacggaag cggtcctgcg cccacaggtc gaggtcgcct cccaggagat ggccgacaag
     1861 gccgccaccc tccacgccga cgcccaccgc acctgcttca tcgccgcctc ggtcaacttc
     1921 ccggtccgcc acgagccggt gatcaccgtc tcatcgctcg caccacgggg caaccggtcc
     1981 gcatgatcga tcctcgatag cggccgatgc gccgcacgaa ccacgtcgga ccacctcact
     2041 caaccgggac ccggcgccgt caggcccggg cgcgcaggcg gcggagcatg cgggcgtcct
     2101 cgaagccgac ggctcgggcg gcggattcga tggtggagcc gtgggagatg aggtgtacgg
     2161 cgcgctcgac gcggaggacc tgctggtagc ggagcggggt gaggccggtg gcttcgccga
     2221 agcggcgggt gagggtgcgt tcgctgacgc cggaggtggc ggcgaggtcg gcgaggccga
     2281 ggtgttcggt gaaacgggcg tcgatgaggt cctggacgcg gtggacggcg tcgctgaggt
     2341 gggcgcggtg ccggagcatc gcgctggtct gctgttcgtc gccgttgcgg cgggcgtaga
     2401 cgaccatgtt gcgggcgatg cgggcggcgg cgcccggccc gtgccggccg gcgacgaggt
     2461 gcagcgcgag gtcgatgccg ctggcgatcc cggcggacgt gacgatccgg tcgtcgacca
     2521 cgtagagcac atcgcgcacg acggtggccc gcgggtggcg gacggcgagt tcgtcctgca
     2581 cgtcgtggtg ggtggtgcag cggcggccgt cgaggaggcc ggcccggccg agggcgtcgg
     2641 cgcccgcgca gatgctggcg acgacgccgc ccgcggcgtg gtggtcgcgc agccgctgga
     2701 gcgtggactc cgccacgtgc ccgttctgcc tcagcgtgcg ggaccgccag cccgggacga
     2761 tcgccaggtc gtcgggggtg aggtcgggcc agcgggtggc cgccctgagc ggtacgccct
     2821 gggcggtcgg gatgtcttcc tgctcgccga cgtaggcggt ctcgtagtcg tagccgaagt
     2881 cggccgcggt cgagaacacc tgcgccgggc ccgcgagatc cagcaggtgc aggtgcggga
     2941 cgagcaggaa gacgacccgg gtcacgatcc ggtcagctcc ttgacggtgg tcacccgggc
     3001 gaaccggccg gcgagcgcgt actcggtgcg cgcgatgatg tcgtcggtct gcagggtgcg
     3061 ggggtcggcg aggatctcct cgaccgagcg gccggccggc gcgtcccagt gctcgcacgg
     3121 ggtggtggcg gtcgcgtcgg tgacgaaggt gacctcgtag ccgaggtcgg aggcgagccg
     3181 ggtcgtcgtc tcgacgcact gctcggtgcg gatgccgctg gtgatgacct cggtgacgcc
     3241 gcgcgaggtg aggagctgct ggaggttggt ggtggtgaag gcgttgtgcg cggtcttggt
     3301 gagcaccggc tcgccgtcga gcggctccag tccctccatc aggcgcacgt gaccgctggc
     3361 cgggtcgaag accccgccgg tgccgggctc gctgtgcagc acccagacga cgaggtcgcc
     3421 ctcgtcgcgg gcgtgcgcca cgaggcggtt cacctggccg acgatgccgg ggttggacga
     3481 ggcctgccac agcgggcgct ggaggaagga ctgctggacg tcgatgacga tcagtgctcg
     3541 gttcatgcct cgatcctggc cctcggcgga gtccgcggta cagacaccat tgtgcctgga
     3601 tgcggaacga tccggtcacc gatcacgcgt cggcgggcgg tccggcgggc ggcagggcga
     3661 gggtgcgcag cgcggcgagc agcgcttcct ggtcgggcgc cgcgccgaag aacgccgcgt
     3721 cggtcgcctc gaccgtggcg accgcctcgg tggccagctc ggcgcccgcg ggcgtgatgc
     3781 cgagccgctt ggcccgggtg tcgctcggat cggtcacgcg ggtgagcagg cccttgtcct
     3841 ccagccggcg cagcacctgg gacgtcatct tcacgtccgt gccgctgtgc cgggccagtt
     3901 ggagctggtt gggctgctcg ccctggctgt cgagccacca cagcccggcc agcaggacga
     3961 actgggcgtg ggtgagatcg agcggcgcca gggccgccgc gatggcgcgc tgccagtgga
     4021 gggaggtgcg ccagaacagg aaaccggggc tgtcgtcggg tgcggccatc atccgaccgt
     4081 acccgtcccc accggccgta agcggattcg ggggcatcaa tcttcgcaga gatcatctac
     4141 gcgcagtctt tattccggtt cgggtgcggc ccgggttcgg ctctcgtgcg gctcagagcc
     4201 gcgccgccat ccgtctcaca cccgccgccg tcccgcgctg agggcaccgt tccctcaggg
     4261 aaacggacgc gatgcggccg ggtaacagcc gcgccgcagg ctgaccggca tggacatcga
     4321 agcgggcacg gagatcgtgg tggtgggcgg cgggatggcg ggtgcgcgcc tggcgcagca
     4381 gctcgcgccc gccgcccccg gcgtccgcgt gacgctgttc ggggaggagg cgcacgcccc
     4441 gtacaaccgg gtgctgctcg ccgaggtact cgccggacgg tacgagccgg acgtcatcac
     4501 gctgccggac gccgcctgca ccgtacggcg cgtggtgcgg gtggaccgcg ccgagcgcct
     4561 cgtgatctgc gacgacggct ccgccactcg ctacgaccgg ctggtgctgg ccaccggctc
     4621 caacccggtg ctcccgccgc tgcgcggcct gttcgaggcc gggcgcggtg aactgccgct
     4681 gggcgtgcac gccttccgca ccatggacga ctgcctggcg ctgtccgggg cgctgcaccc
     4741 cggcgtgcgg gcggtcgtcg tcgggggcgg gctgctcggg gtgtccgcgg cgcgggcgct
     4801 ggcggcgcgc ggcgcccatg tcgtcctgct ccagcagggc gagtacctga tggagcggca
     4861 gctggacgag cagtccggca ggctgctgcg cacgcatctg gagtcgatgg gcatcgaggt
     4921 ccacacggag tgccgggtgc ggggactgcg gaccgccccg gacggtacgc cgcaggccgt
     4981 ccgcgccgtc cggtccgtcg aactcgccga cggctactgc ctcggcaccg acctggtcgt
     5041 tctcgcctgc ggtgtgcggc cccgcaccgg gctggcgcag gcggcggggc tcgaggtcga
     5101 ccggggcatc gtcgtggacg acgagctgcg gacgtccgac ccgttcatcc acgcgatcgg
     5161 cgactgctcg cagcacggcg gtgtcgtgta cggcctggcg aacgcggccc gtgaacaggc
     5221 ggacgcgctg gcgctgctgc tcaccgaggc ggcgcggggg cccgcccccg gccgccccgc
     5281 ggacccaccg cgctacaccg gcacccgcgc cctgacccgg ctgaccctcg gcggctcccc
     5341 cgcgcccgca gccaacgcct cagagcccgc ccgtaccggt gccaccggga tcgccccctt
     5401 cgacctcgcc gcgttcggcg acccgctgcc ggtccccggc gacgacgtac tgcgcctcac
     5461 ggacgcgacc cgcggcgcct accggaaggt cgtcatccgt gacgaccggc tggtcggcgg
     5521 gatcctgctc ggcgatctcg ccgcggtggg cacgctcgcc cgcacctggg aggccgacga
     5581 gccgctcccg gcctcatccg ctccgctgct ccacctgctc accaacgacg gaggttcctg
     5641 accatggctg ttgacacgat ggctggcggc acgacggacg ttcccacggt tccgacgatc
     5701 gtgctggtcg gacacggcat ggtcggtcag cggttcctgg aggcgctcgc cgaccggggc
     5761 gtcaccgagc gggcgcgggt ggtcgtgctg tgcgaggagc cccgcgcggc gtacgaccgg
     5821 gtccatctga cctcgtactt ctccgggacg acgccggacg gactcgccct cgccgaggac
     5881 ggcttcatgg agaagcacgg catcgagctg cggctggggg atcccgcgct caccgtcgac
     5941 cgcgcggccc gcaccgtgac cgcccgctcc gggctgacct tcgggtacga cacgctggtg
     6001 ctggccaccg gctccttccc gttcgtgccg ccggtcccgg gcaaggacac cgagggctgc
     6061 ttcgtgtacc gcaccatcga ggacctgctg gcgatcgagg agtacgccgc gaccggcggc
     6121 accggcacgg tcgtcggcgg cggactgctg ggcctggagg cggcgggcgc cctgaagggg
     6181 ctcggactgg acacgcacgt agtggagttc gcgccgcgcc tgatgccggt gcagatcgac
     6241 gagggcggcg gcgaggcgct gcggcgcacc atcgaggaga tgggcgtcac cgtccacacg
     6301 ggtgtcggca cccaggcgat cgtggcgggc gaggacggca gggtcgccgc gatgtcgctg
     6361 tcggacggct cgacgctcac gaccggcctg gtggtcttct cggccggcgt ccgcccccgc
     6421 gaccagctgg cccgggagtg cgggctgccg gtcggcgagc gcggcgggat cgtcgtggac
     6481 gagcagtgca ggaccgagga cgaggcggtg tacgcgatcg gcgagtgcgc gctggcctcc
     6541 gacggccggg tgtacgggct ggtcgcgccc ggctacgaga tggcggagac ggcggcgaag
     6601 gcgatcgcgg gcgacgcggg ttccttcaag ggcgcggatc tgtcgacgaa gctcaagctg
     6661 ctcggcgtgg acgtggcgag cttcggcgac gcccacggcg ccacccccgg ctgcctggac
     6721 gtgctgtact ccgactcccg ttccggcgtg tacaagaagc tggtggtctc gcgcgagggt
     6781 gtgctgctgg gcggcatcct ggtcggcgac gccgactcgt acggcatgct gcgcccgatg
     6841 accggctcgg tgccgccggt gccgcccgag cggctggtgc tgcctgcggg cgccggaggg
     6901 ccggtcgaac tcgggccgtc gtcgctgccc gacacggcgg tgatctgcag ctgccacaac
     6961 gtcaccaagg gcgcgatcct cggcgccgtc accgagcact cctgcaccac cgtgccgcag
     7021 ctcaagaagt gcaccaaggc cggcacgggc tgcggcagtt gcctgaaggt gctggggcag
     7081 ctgctgccgc ccgccgagga caaggggctg tgcggctgct tcgcgcacac ccgccaggag
     7141 ctgtacgaga tcgtgcgcgc gctgcgggtc acctcgttcg cggcactgct cgacagccac
     7201 gggcgcgagg cggccagggg cggcgagggc tgcgaggtct gcaagccggc ggtggcctcg
     7261 gtcatcgcct cgctggcgcc gtcgatcggc gctccggtgc atgtgctgga cggcggacag
     7321 gccgcgctcc aggacaccaa cgaccacttc ctggcgaacc tgcagcgcaa cggctcgtac
     7381 tcgatcgtgc cgcgtatccc cggcggtgag atcaccccgg agaagctcat cgtgatcggc
     7441 gaggtggccc gggacttcgg cctctacacg aagatcaccg gcgggcagcg gatcgacctc
     7501 ttcggcgccc gtgtcgacca gctgccgctg atctggacac ggctggtgga cgccgggttc
     7561 gagtcggggc acgcgtacgg caaggcgctg cgcaccgtga agtcgtgcgt gggcagcacc
     7621 tggtgccggt acggcgtcca ggacagcgtg aagatggcca tcggcctgga gttgcgctac
     7681 cgggggctgc gctcgccgca caagctcaag tccgccgtct cggggtgcgc ccgcgagtgc
     7741 gcggaggccc gtggcaagga cttcgggatc atcgccaccg cgtcgggctg gaacctgtac
     7801 gtcggcggca acggcggcgc cgacccgcgc cacgcggacc tgctggcaca ggacctcagc
     7861 gacgcggaac tggtccggct catcgaccgc ttcctgatgt tctacatccg caccgccgac
     7921 cggctggagc gtacctccgc ctggctggag cggatcgagg gcggcctgga gcacgtccgc
     7981 gacgtcgtcg tgcacgactc gctgggcatc tgcgacgagc tggagtcact gatgtccgcg
     8041 catgtcgcgg ggtaccgcga cgagtgggcc gacaccatca acgaccccga gcggctgagc
     8101 cgcttcgtct ccttcgtcaa cgcgccggac gtgcccgacc ccagcgtccg gttcgtcgag
     8161 gagcgcgacc aggtcaagcc cgatctggat ctgctggccg gcccggtgct gctggccggc
     8221 cccaccctcg ccatccgcac cctcgaaggg acggtcaccg catgaccatc gaactcctcc
     8281 tcgacgacgc ctggttcccg gtctgcgacg acgccctgct gaccccgggc cggggcgtcg
     8341 ccgccctgct gcccgacggc tcgcaggccg ccctcttcca ggaccgccac ggcgccctct
     8401 acgcgatcgg caaccgggac ccgttcaccg gcgcctacgt gctgtcccgc ggcctgctcg
     8461 gctcggcggc gggccgggcg tacgtcgcct caccgctgct caagcagcgc ttcgacctgg
     8521 cgaccggcac ctgcctggac gacgaatcgg tcagtaccgc ctcgtatgcc gtcaggtccc
     8581 agtaatcccc catacagcgc gaccgcgtca cgtaatgtgg cgaatgcaca gcgaattgac
     8641 aaggttaggt ttacctaacc taagatcgac cggtgctcaa gacccagcgg acggccgtcg
     8701 ccggccagct cccctccccg gtccggcgga taccgctgtt cctgctcggc gccgtcgcgt
     8761 tgacggcgtg cgccgccgcg agcctcgcac tcggctcgcg gccggtcccc ctcggcaccg
     8821 tgctcgacgc cctgttccac cacgcccaca gccgtgacgc cgtggtggtc accgggctgc
     8881 gcgtaccgcg caccctgatc gggctcgcgg tcggcgcggc gctcggggtg gcgggcgccg
     8941 tcgcccaggg cgtcacccgc aacccgctgg cctcgccgac cacactgggg atcaacgcgg
     9001 gcgccggctt cgccgtcgtc accgcgatct acgcactgca tctgacgcac ccttcccagt
     9061 acttgtggtt cgcgttcgcc ggagccgcgg ccgccgcgct cttcgcccag acgctcgccc
     9121 ggcgggcggg cgacctggac ccggtacggc tcgcactggg cggcacggtg ctgacggccg
     9181 tcctggtgtc ctggacgtcc gccgtgatgc tggcgagcaa ccgcaccctg gacgaagccc
     9241 ggttctggct cgccggctcg ctctcggggc ggacactcga cgtcctctac cccgtactcc
     9301 cgctgatcgc cgtcgggttg gtcatcgcgc tggccatcac cccggcgctc aacgccctgg
     9361 ccctcggtga cgagaccgcg caggccctgg gcgtgccggt ggccaggatc cgggtcgccg
     9421 gcggcctctc cgtggtgctg ctcgcgggct ccgccgtcgc ggtggcggga ccggtcgcct
     9481 tcatcgggct ggccgccccg cacctggtgc ggctggtgtt cggcaacgac caccggctgc
     9541 tggtccccgg ctgtctgatc gccggcccgc tgctgctgct cggcgccgac gtcctgggcc
     9601 gcgtcatgat cgcgccctcc gaactggagg tcggcatcgt caccgccttc ctcggcgcgc
     9661 cgctgctcgc ggtgctggcc cggaaggtgg cccgatgacg ccgcccgccc ccacgacccc
     9721 gcccacgccc gtgaccccgc ccgcccccac gacgacgcag tccctcgtcc ccgcaccccg
     9781 gaaggatgcc aaggatgcct ccgccgcccc gaagcggcgg ccctcccgcg ggcgccggac
     9841 cgcgctgttg agcgtctgcg ccgtggcggc gatcctcgta ctggccacca ccgcgctcac
     9901 caccgggcag atcctgatgc ccccgctcac cgcgctgcgc gccctgatcg gcctcggcga
     9961 ctccggcgac gtgctggtgg tccaggagtt ccgggcgccc cggatggcgg cggcgatcgt
    10021 cgccggcgcg ggcctcgccg tcgccggcgg gctgctgcag cggctgttcc gcaacccgct
    10081 cgcctccccc gacgtcatgg gcgtgaccgg cggcgcctcc ctcggcgccg tctcgctgct
    10141 cgccaccggc gcctcgcaga ccctcatccc gctggccgcc ctcggcggcg ggctgctcgc
    10201 cgccgtcctg ctcggcgcgt tcgcctggcg ctcggggctc ggcgtcaccc gtctcgtcct
    10261 ggtggggctg gccgttcagg cgggcctggc cgccgccgtc aacctgatgg tggtgcgctt
    10321 ccccgccgaa ctcgccaact ccgcgctgca gtggacgacg gggtcgctct acgggcggac
    10381 ctggaccgag gtgtccgccg ccggcggcgc cgtggccgcc gcgatggccg ccgcgttcgt
    10441 cctccaccgg cgcctcgccg tcctcgacct gggcgacgac tccgcgggcg ggctcggcct
    10501 ggcgccgtcc gccgcacgcc tccaactgct gctcaccgcc atcgtgctgg cctcgctggc
    10561 cgcggcgctc accggcccgg tcgcgttcgt cgcactcgcc gtaccgcacg tggtccgttt
    10621 cctcgccggg ccgccgaccg ccggaacgct cgcgctgtcg gccctcaccg gcgccgtcct
    10681 gctgctcggc tccgacctgg tcgtccagca tctgctgccg gtgcacggac tgcccgtcgg
    10741 cgtggtcacc gcgaccctcg gcgccccctg gctactcgtc ctgatgattc gtcagagcag
    10801 gcccacacac cggagtttcg gatgaccgcc cgcgccgacc ggccgaaccg caccaaccag
    10861 ctctccaccc acggcctgga cctgcgctac ggcgaccgtc tggtgatcgg cggcctggac
    10921 ctcgtcctgc ccggcggcgc cgtcaccgcc atcgtcggcc ccaacgcctg cgggaagtcg
    10981 acgctgctgc gcgggctgtc ccggctgctc tcccccgccg ccggcactgt ggccctggac
    11041 ggcgcggaca tccaccggat gcccgcccgt tcgctggccc gccggatggg gctgctgccg
    11101 cagcagccgg tcacccccga ggcgatcacc gtcgaggcgc tggtccggct cggccgctac
    11161 ccgcaccagc ggctgctcag cccctggtcg gccaccgacc aggccgccgt cgacgaggca
    11221 ctggagcgca ccggcaccac ggaactgcgc gaccagcacg tggaccagct ctccggcggt
    11281 cagcggcagc gcgcctggat cgcgctggcc ctcgcccagg acaccgagct gctgctcctc
    11341 gacgagccca ccaccttcct cgacctgcgg caccaactcg acgtcctcga cctggtgtcg
    11401 gacctgcaca ccgagtccgg gcgcaccgtc gtcatggtgc tgcacgacct cggccaggcc
    11461 gcccggtacg ccgaccatct cgtcgtcctc caggagggcc ggccggccgc ggccgggccg
    11521 ccctccgagg tgctcgacgc ggcgctggtg aaggccgtgt tcgacgtgga ctgccaggtc
    11581 atccccgacc ccgagaccgg caccccgctc gtcgtgcccc gcggccgcgc cagacggcac
    11641 gccaccgccg tcgccggctg agccccgacc tttcccttcc cccgtccccc tctcctgtcc
    11701 agtcgcaagg aacccccacc ctcatgaaca ccagagcccc gctccaccgc cgtctcgtcc
    11761 ggctgatcgc cgcgcccgtc gccctcgtca tcggcgtggg agcgctcgcc gcctgcggca
    11821 gcgggaccgc ggccaaggac gacaaggcga acgccgcggc caccgccgac ggtttcccgc
    11881 gcaccatcac gcacgccatg ggcagcacca cgattcccgc gaagccgcag cgcgtggtcg
    11941 tgctcgacac cggcgagctg gacgacgtga cgatgctcgg catcaccccg gtcggcgcgg
    12001 tcgcaccgca cctcaagtcc gagggcggct tcccggcgta cctgcagggc aggaccgagg
    12061 gcaccaagga tgtcggcccg tccgcggagc ccgacctcga gctgatcgcg tccctcaagc
    12121 cggacctgat cctgtcctcg aaggtccgcc acgagaaggt ctacgacaag ctcaaggcca
    12181 tcgcgccgac cgtcttcacc gcgaccaccg gcttcccctg gaaggagaac ctggccgtcc
    12241 acgccaaggc tctcggcctg gagaaggaag ccgctaccgc gctgaagtcc tacgaggacc
    12301 gcgccaagaa gctcggtgcg gccatcaagt ccaggaacgg cggcaaggag ccgaccgcct
    12361 cggtcgtccg cttcgtcgcc ggcccgaccc ggctctacca gctggactcg ttcagcggcg
    12421 tcgtgctgag cgacatcggc ctgggccgcc cggcctcgca gaacgtccac agcgcgatgc
    12481 tggaggtcgg ccccgagcag atcgacaagg ccgacgcgga cctggtcttc gtcaccgtct
    12541 ccgacgaccc ggccaagacg cggcagagcg tcgtcgagtc caacccggtc tggaaggacc
    12601 tgggcgcggt caggaaccac aaggtcgtca acgtgaccga cgagacgtgg atgtccggca
    12661 tcggcgtcca ggccgcgctc agcatgctcg gcgacgtggc caaggccgcg ggcgtcgacc
    12721 tgccggagta acgcttcccg tgtgagaggg gcgggcctcc cccggcccgc cccctcccca
    12781 ccacacgttc ccagaacagg actctcagcc atgcggctgt atctgctcgc gctcaacccc
    12841 acggactccg tcaccgaggg tttcctgccg gccgcctccc ggctcggcct ggacgtcacc
    12901 gtcctcaccg actcccccgc cgcccaccag gagctgtacg gcacccaggt ggacgtcgag
    12961 gagtgcgacg tacgcgactt ccgtgccgtc atcacccgga tcgccaccgg ccgcaccccc
    13021 cacgccgtct tcaccaacag cgaccacctg cagacccaga ccgcgctcgc cgccgagtac
    13081 ttcggtctgc ccgccaagcc ctggcaggcc gccctgcgca ccaaggacaa ggcgcagatg
    13141 cgccgccacc tggccgccac cggcgccgac accgtgtggt ccgccgaact cgcggccggc
    13201 gcggaccccg cctcgctgct cggcctgccg gtcccctacc cgtgcgtggt gaaaccgcgc
    13261 gagggcgtgg ccagcgagga cgtggtcctc gtcggcggcc ccgaggaact ggtgctgcgc
    13321 tgcaaggaga tccaggcccg ccgcccgcag gcggcgctcg tggccgagga gtacctcacc
    13381 ggcgagctgt acacgctgga gacactcggt gacggccgga cccggcacgt gctgggcgga
    13441 ttccacaccg ggctctcgcc gctcccctac ttcatcgagg aacggctcac cttcgttccc
    13501 gagcaccccg ccgcggtcgt cgagcagatc ctcgcgcaac tggacgccct cggcgtcggg
    13561 ttcggcgcct gtcacaccga gttcgtggtc caggacggcc gggcgcgcat catcgaggtg
    13621 aactaccggg ccatcggcga ccagtgcgat ctgctgctcg ccgggctgct cgacatcccc
    13681 ctcttcgagc acatcctccg cgtccacctg ggcgaaccgc tccccgccga cctcggcgcc
    13741 cgcggcggcg gccgcgcccg gctggagtac ccgtgcgcgg accgggcggg caccctgacc
    13801 gccgcgcccg aggccaccga gcgcacggtg gacggtgtcc ggctggtcta ccgcccgctg
    13861 cgcgcgaccg gtgaacggca cgaactgcac cacaccaacc gggacctcct cggcatcgtg
    13921 cgcgccaccg gaaccgacca ggaggcggtg gaccgcgtcg tgacggactt cctccgggcg
    13981 cagcgctggg agatcacccc atgacgggca cccgtacgac cgatgccggt gtggacgcgg
    14041 aactgatgct gcgcgtgctc agcgcgctgc tgcgcgagga cgtcgtcggg ctgcgcaccc
    14101 gctccaccct cgtcgaggag tccgacggcc gctggctgcg gctgccgtac acctacggcg
    14161 gtgacggggc cggcgggttc gggaaagcgc tgctgctccc ggtgaccgac gacggcttcc
    14221 agagcgagta cgccgcccgg ctgccgctgc tgcggcgcgc ctcggacggc cgcgaactca
    14281 ccggcgccga cgccgtgctg cgggcactgc gcgccctggc ggaccccgtc gaccaggccg
    14341 gcttcgacgc gttcgccgag gagtgccggc agaccgcggc gaccctgcgg ctgcacgacc
    14401 gggtgcgcgc ggaggtgacc ggccggctcg ccgagcgcta cggctccgac accgcgtact
    14461 ggacgtacgc ccgcagcctg ggcttcgacg cgctggccgc cttccacgac cacccggtgt
    14521 atccgacatc gcgcggccgc agcggcctcg gcgagtccga cctgcgcgcc tatgcgccgg
    14581 agttccacga ggacgtcgca ccgcgctggc tcgtcctgcc ccgtgatgcc gtgacggagt
    14641 ccggcggcgg ccccgccgag acgtacgcct atctgtggcc gacacccgcc tccctcggca
    14701 tgccggagct gcgcgacacc cacaccgtgc tcccggtgca cccgctgacc gtcgggacgc
    14761 cgctggacga ggcgctgcgc gccaccggtc tggaagggcg cgcgttcctc gccgaacagg
    14821 cgccgctgtc cctcgtcccc accctgtcca tgcgcacgct cgcggaccgt acgtatccgc
    14881 tgctgcatct gaagctgccg ctggccaccg cgaccctggg gctgcgcaac cggcggacca
    14941 tcaagccggg cacgctcgcc gacggggccg cctgccagct gctgctgagc gaggtgatcg
    15001 cccgcgaacc ccggttccag gacaccgtgc tgctcgccga cgagcgccgc tacgcgcacg
    15061 ccgggcacga gctcctcgcc gtcctgctgc gccgctatcc ggagcacctg cagaactccg
    15121 tcctggtccc gatagccgcg ctgctcgccg gcgccccgga cggccggctg gtgatcgacc
    15181 agctcgccga ccgcttctac gacggcgacc ccatcgctct cctggacgcc tgcctgacac
    15241 tgctgttcga ctggcagacc acgctcttcg gctacgggat cgccctggag tcgcaccagc
    15301 agaacatctc cctcgccctg gaccaggacc gcacgacggg caccacccgg ctgcggctgg
    15361 tcctcaagga caacgacggg ccacgcatca acaccgcgcg actgagccgg gcactgggcg
    15421 aacttacggc caggatcgac gagttcgacg acgaacggat cttctgcgtc tccgacgaac
    15481 cgctcatcga cctgttcacc accatcaccg tccacctgtg cgcgggctcg tacgccttcg
    15541 ggctggccga ccacggccgg gcgccgctgg acgacctgct gcggctggtc cgcgaccggc
    15601 tctccgaggc gttcgaccgt ctgggcggcg agccggccga gctgctgcgc gaacgcgtgc
    15661 tgaacgccga gcggctcccg gtcaaggcga tggtcagcgc cgggaccctg ctcagcaagg
    15721 agcgctccgg cgcggccgac atcaacaagc actacacgac cggccccaac tacctgctgg
    15781 tcgggactgg ttcgcggtga gcgccgaggc ggcgacgatt tccgccgctc cggctcccgc
    15841 cctggggcgc cgccaggtgc acgccgtcgc ggcctgctac ttcgtcgcct cgttcgccgc
    15901 gctcggcctg cccccgtacc tgacgtccat cctgccggag ctgggtgacc cgaccgcgca
    15961 ctgggccggg ctgctctaca tcgtcccgac ggtcttcggc ggcctcgccg ccccgctgtg
    16021 ggggcggctg gccgaccgct acggccgcaa acggcttctg ctgcgggccc agttcgggct
    16081 ggcgctgtcg ttcctgctgg ccggggccgc cgactcgctg cccaccttca ccgccgccct
    16141 cgtgctgcag ggcatcctcg gcggcacctt cgccgccacc aacggctatc tcgcggcggg
    16201 gctggacggc acccggctgt cctgggccct gaccctgatg cagggcagcg cccgcgccgc
    16261 cctcgtcgcc gcgcccatcg tggtcggcac gctgtccccc tggctctccc cgcaccgcca
    16321 gtacgcgctg ctcgcgctgc tcccgctggg cgccgcggcg atgctgctgg cactgccgga
    16381 accgcgcgag accgtcgtgg tcatggagaa gccgcgggcg gagcagcaga tgctcggagc
    16441 tgagccggtc gagatcgcgg tggtagcgcc gccggtcacc gcgcagcgcg ggctcctgcg
    16501 ggagctgtac ctcttcgagt tcgcgttcgt cttctcgacc gtgatctcgt tcccctacct
    16561 catcgccctg ctcggggacc gaatatcggg gatctccccg gtcgtctccg ggtcgctctt
    16621 cgccctgccg cacctgtgtt acctgctctt cgcggcgccc gtgcactccg ccttccgcaa
    16681 ccgcccccgg ctcggtatcg ccctcggttt cacggcggtg accgcgggtc tcgcggggca
    16741 tgccgtggcc ggttcgctga tcacgttcac ggccgtccgg ctgctgctcg gcgccgggct
    16801 cacgctcggc ctggtcggtc tgtccctgct cgccgccgac gcggtgcaag gccgctcgcc
    16861 gggaaggatg ttcggctccc tggagttcgt ctccaagggc ggggccgtcg ccgccggagt
    16921 ggtcgccgca ctcggcaaca gcgccttcgg accgaccgcg cccgtgctcg cgggcaccgc
    16981 cgtcgctctg atcaccgtcg cagccgccgt acacgctctc ttctcgcacc cttgatggag
    17041 ccgttgatga cgcttcccct gcacctcgcg cagccttccg ccggcctttc cgccagcgcc
    17101 ctttccgcca gcggtcttca cgccagcggt cttcccgacg ccgatgacgt cgtggcccac
    17161 accctcctca actgcctgct ccgcgaggta tcgggacccg agcaccagac cgcggtcgcg
    17221 gacggccacc tcctgctgcg gctgccccgc gcggacgcgc tgctgcgtgt cgcgctgcgt
    17281 cgcacctcgc tcatcggcgc ccaccggttc accggccccg tcgcggagca acacgcggac
    17341 gggtggaagg agttggactg gtaccgactc gccgagtacg tgcacgacga gctgtcactg
    17401 cgcaccgggg tgcgcaacga cgagttcctc gaccagatcg tctccagcca ccggggcgtc
    17461 gccgccgcgc tgtcgctccc ccgtccggtg cccggcagcg acgacggtcc cggcgccccc
    17521 gactacctgg agtccgagcg gtccctgctg ttcggtcacc gcttccaccc cacccccaag
    17581 gcgcgcaccg gcgacccggc gtcgtgggcc gcgtacgccc cggaggcggg cgcgacgttc
    17641 ccgctgcggc acttcgccgt ccgcgagcac ctgatcgcgg aggagcgcag cgaacccggc
    17701 gccgccgacc cgctggaccg gctgcggccg gtgcccgccg gctaccggct gctgcccgcg
    17761 cacccgtggc agtacgggct gctgcacgac cacccggcgc tgcgcgccgc cctggcctgc
    17821 ggcgacatcc tcgacctggg caccggcgac gcggccgcgg caccgaccgc gtcggtccgc
    17881 acgctgtacg acggcgacac gttcctcaag ttcagcctca acatccggat caccaactgc
    17941 ctgcggaaga acgccgctta cgaactgtcc ggcgcggtcg cgctcacccg cctgctggcg
    18001 ccggtcctcg ccgacctggc cgggcgcttc ccggacagcg ccatgctgcg ggagcccgcg
    18061 taccgcagcc tcgcgctgcc cggcgccgac gggcgcccgg acatcggcct gctggaaggc
    18121 ttcggcgtca tcgtccgcga cggcctggcc gcgcatctgc gccccggtgt caccccgctg
    18181 ctggcggccg ccgtcgccga cgagtacccc accggctccg cgcacatctc gcggctcctc
    18241 gacggggcgg gcccacaggc cgccctcgac tggtggacgg cgtatctgcg actgctgctc
    18301 ccgccggtgc tcgccgccta tttcgaccac ggcgtcgtgc tggaaccgca tctgcagaac
    18361 gtgctgatcg gggtggacgg cgacggcttc ccggtccagg tgctcttccg cgatctggag
    18421 ggcaccaagc tcctccccga gcaccatgcc gccaccctcg ccgcgctgcc cgccgatgtc
    18481 gcggccccca tgacgtacga cgcggaacgc ggctgggacc gcgtcatcta ctgcctgctc
    18541 gtcaaccacg tcgccgaact gctcgcggcc ctcgccgatc tgcacccgca gtccgagacg
    18601 gcgctgtggg cgcgggtgca cggcgtgctg cgcgagtacg cggacgacca cggctgcccg
    18661 ccccggctca gcgccctgct cgccggggtc ccgctgcccg ccaaggccaa cctcctgacg
    18721 cgctgggagc gcaaggcgga ccgcgaggcc ggctacgtac ggctgccgtc tccgctggcc
    18781 gaggacgtgc tgtcgggggc gtcggcgccg ggcgcggcgg gctgcggaac cggcggcgac
    18841 gacagcgacc ggaccgagcc ctggagcacc cgatgacccc gaactcctcc gccggcccgg
    18901 cgctgctgac cgacgcggtc cgcgaccggg ccacgtacct cgccgccgac gacctgcccg
    18961 cctacctcta cgacctggcg gagctgcgcg cccacgccgc cgccgtacgg gccgcgctcc
    19021 ccgagcgcgt cgagctctac tacgccgcca aggccaaccc cgagccggag atcctgaccg
    19081 cgctcgcccc gtacgtcgac ggtttcgagg tctcctccgg cggcgaactg acccatgtcc
    19141 gcaaggccgt cccggaccgc ccgctggcct tcggcgggcc cggcaagacc ccggccgaga
    19201 tcgcggcggc gctggagctg ggcgtggaac gcttccacgt ggagagcgag tacgagctgc
    19261 gcatgctcgg ccacctcgcc gcgcggccgg cccccggccg gaccgttccc gtcctgctgc
    19321 gcttcaacct gccggtgccg ggcgcggcgc tggaaggcag ttcactggcg atgggcggct
    19381 gcccgacccc gttcggcctc gaccccgcac aggccgacag cgccgtccgg ctgctcaccg
    19441 acggcagcca cccccaactg gagctgcgcg gcatccacgc ccacctcgcc agcggcctcg
    19501 acgcgacggc gcagctcgcc gtggccgccg aggtggtggc gttcgcggtg ggcctggccg
    19561 cccggcacgg catcgcgctg cccgaggtga acgtcggcgg tggcatgacc gtggactacg
    19621 ccgatcccgg cgcccgcttc gactggaccg cctacggcga aggcctcgcg cgcctcatcg
    19681 ccgcccaccc cggcctgctg ctgcgtatcg agccgggccg cgccctcagc gcctactgcg
    19741 gctggtacgc caccgaggcg ctggacgtga agcccagcca cggtgaggag ttcgccgtgc
    19801 tgcgcggcgg cacccaccat ctgcgcaccc cggcgacgaa gggccacgac cagccctgcg
    19861 aggtcctgcc cgtcggccac tggccgcacc cctggccgcg ccccgccgcc ggacaggacc
    19921 acgtcaccct caccggccag ctctgcaccc cgaaggacgt cctcgcccgc cgggttccgg
    19981 cgcccggcct gcgggccggg gaccgcgtag tgttcgcgct ggccggggcg tacgcgtgga
    20041 acatctccca ccacgacttc ctgatgcatc cccggccggg cttccacttc ctgggcagtg
    20101 cttgaatcgg cccatgaccg atcatgaagt gctccgggtg ttcatcggcc ccgacggccg
    20161 gggcggcaac ctcctgggcg tggtgtcggc cgactcctcc gacccggccg cccgccaggc
    20221 gatcgccgcc gaactcggct acagcgagac ggtgttcatc gacgacgcgg agcgcggcga
    20281 cgttcggatc ttcaccccca gcgtggaact ccccttcgcc ggccaccccc tcaccggcac
    20341 cgcctggctc ctgaagtcgt ccctcctgcg cccgccggcc ggcgacgtcc ccgcctggac
    20401 ggagggcgac ttcacctgga tccgcggccg cgccgcctgg gcccccggcc gccgcaccga
    20461 gcagtacccg acggtcgccg aggtcgacgc cctgccctcc ccgccaccgg gcgagggctg
    20521 gctctacgcc tgggcctggg ccgacgaagc ggcgggccgc gtccgcgccc gcggcttccc
    20581 ccgccgcggc gacgcgatca ccgaggacga ggcgaccggc gcctccgcga tcgtcctcgc
    20641 cgcccaactc gcccgccccc tcgacatccg ccagggcacc gcctcccaga tcctgacccg
    20701 cccgggcccg gacggcacga tcgacgtggg cggccgggtg gcagccgtgc gctgaaggcg
    20761 cgcgaggggc cggtgatcca ggggtgggcc ggaccgcggc tgagtagggt ctgccggatg
    20821 actctttctc atgacgtggc cggagacggc ccggccgtgg tgctgttgca ttccggggtg
    20881 tgcgaccggc ggatgtggga cgcgcagtgg acggacctgg tcgacgccgg gtaccggccg
    20941 gtgcggtgcg acttccgggg gttcggccgc agtcccgtgc cggaccggcc gtacagcaac
    21001 gccgacgacg tgctggacct cctcgacacc ctcggcatcg agcgggccgc gctggtggcg
    21061 tcctcctccg gcggccgggt cgctctggag atcgcggcgc gccggccgga gcgggtgagc
    21121 gccctggcgc tgctctgttc cgcgcttccc ggacatgagg tcagcgccgg gctgcgcgcg
    21181 atcggcgcgc gggaggacga actgctggag gcgggggacg tcgccggggc ggtggagctg
    21241 atggtcgaca cctgggtggg tcctgcgggc gggccggacg tccgggaggc ggtgcgcggg
    21301 atgcagcggc gcgccttcga cgtacagctg gccgccctcg aggagttcga gccgatcagg
    21361 gccgagttcg acctggcggc ggtcacggcg ccgtgcctcg ccgtgtcggg cgcccatgac
    21421 gtgacggact tccgggagat cgccgccgcc ctgcccggcc tgctcgccga cgcccgccac
    21481 gtcgaactgc cctgggcggg ccatctgccc agcctggaac ggcctgccgc cgtcaccgaa
    21541 cttctcgtcg gcttcctgcg cggaacggta cccgctgcgg ggcgctgacc ggccgcgagg
    21601 ccgcacgcgt acgtgccgtt cttgtcctgt cacgcacatg cctcgtgcat cggcggcccg
    21661 ctctctaagc tgaccgccgg gggatccgga tttcggccag cgacacgagg agaaccggtc
    21721 acatgggctg gactgcgaac gacatccccg accagaccgg acgcaccgcc gtggtgaccg
    21781 gggccaacag cggcatcggg tactgcgccg cgaaggaact ggcgcggcgc ggggcgctgg
    21841 tcgtcctggc gtgccgcagc gaggagcgcg ggcaggcggc ggcggaccgg ttggtggccg
    21901 aggtcccgga ggcgcgggcc gtgttccaac ggctggacct gggggacctg gggtcggtgc
    21961 gggccttcgc ggaggagttc gcgggcgacc ggctggatct gctggtgaac aacgcggggg
    22021 tgatggccct gccgtacacg cagaccgccg acgggttcga gacgcagttc ggcgtcaacc
    22081 acctcggtca cttcgccctg accggcctgc tgctgccgaa gctgctcgcg acacccgggg
    22141 cccgggtcgt cagcgtctcc agcgggatgc acgcgatcgc caacgtggat ctcggcgacc
    22201 tgaacagcga gcgccgctac cgccgctgga tcgcgtacgg ccgctccaag agcgccaatc
    22261 tgctgttcat ccacgagttg gcgcggcagt tggggacgac gggcgcggac atcgtggccg
    22321 ccgccgcgca ccccggctac gccgaaacga atctccagac ggcgggcgcc aaactggagg
    22381 gccgcaggcg cgccgagcgc gtcatcggga tcggcaaccg gatcatcggc cagtcggccg
    22441 cggcgggcgc gctgccgacg ctctacgcgg ccaccgcacc ggacgtggcc cccgattcgt
    22501 tcaccggccc ccgcctgcag ggctggcgcg gcgcgcccag ccgctcctgg cgcgcctcct
    22561 ggacgaagga cgaccgcgcg ggcgagatgc tgtggacggc gtccgagcag ctgacgggtg
    22621 tgacgtacaa gttctgaggc ccgggatcgg acgcgccggg ggaacgcgta ccgctgcgcg
    22681 cgggtgctac ccgccgtaga gctcctccag cacccgcgcc accccgtcct catcgttcgt
    22741 ggcggcccgc agcggcgccg cggccaggac gtccgggtgc gcgttgctca tcgcgtagcc
    22801 ggctcctgcc caggtcaggg tggacaggtc gttcggcatg tcgccgaagg agaccacctc
    22861 ggaggcgccg atcccgcggg ccgcgcacca cagggcgagc gtgccggcct tggtgacacc
    22921 gggcgagctg atctccagca tgccggagcc gccggagtgc gtgacctcga cgccggtgag
    22981 cgccgcgtcg tgcgccgcgg tcatcatccg gtccgcgtgg tgccgcgacg agtgcacgag
    23041 gagcttgacg atgtcctcgt ccgactccca cagctcggcg gcggtctcca cgatcacctc
    23101 ctggaagtcc ttcttcccga agtcccgctc gctgatgagg cggtggccgg tctccagggc
    23161 gagcgtcgag ccgggcagca ccgcgacgag cgcctccgcc gccttgcgcg cgacggggtt
    23221 cggcatcagc cgtgcgtcga ggaactgccg gccggggacg tcgtagacga tcgcgccgtt
    23281 gcagcagatc gcggtcccct cgtgcccggc gccctcggcg atgccgtcca cgtaacgcgg
    23341 cggccgcgcc gtcacgaaga cgacctcggc gcccgcggcc gccaccgacc gcagcgcccg
    23401 ccgggtccgc tccgagaccg ttccgtcgct gcgcagcagc gtgccgtcga ggtcggtggc
    23461 caccagccgg ggaggggttc gggagggaga agcagtcatg ttcggatcat ggcagatacg
    23521 ccggaaaagg gtggagacga aaggtggagg cagggcggcg tggggtgaaa cgacgggggg
    23581 cgacgaggga gaacgggctc ctgggaccac gggaagggtg cgccccgtac aacttcccat
    23641 ggccatcagg tgtcttgcag tgaacacatg gccatttcgg ctctgtggct cacggggcga
    23701 aggggacacc gatgggacgg cacacaaggg cgattctggc cggattggga ctcgcggggc
    23761 tgctgctggc ggccggtccg gcggccgagg cgcaggcgga tgccggcccg gtggacgccg
    23821 acgtccagat gcagttcctc cacccgcagg tggctcccgg ccggcagttc cacttctatc
    23881 tcctcacgca cctgaagtcg ggcacactga gcacgttccg cggcttggtg cacctgccgg
    23941 agggcatgac gtacgttccc gtggtggaac gtacgtgcga gcccacgtcg gcgaacaagc
    24001 gggagatcgc ctgtcgccct gatagccaga gtctgaccgt ccaggtcgcg gacgatgtac
    24061 cggtcggcac caggctgacg atcacggcga cggccgacat cggcgacgcg gtcgacacgc
    24121 atccggagga caacaccgct cgacaggagg tgctggtcaa gccgggcgcg gactggagcg
    24181 tcaagtggac cggccccacc accccggtgc agcccggcag cacaccggtg accacacggc
    24241 tggtcgtcac caatcacggc caggaggccg acctcccgtt catcctcacc agcggcccgg
    24301 gcgactaccc gaggcagatg gagtactacg ggaagtggga caagacctgc ggcatcgcca
    24361 ccgagggaaa cggcctgttg tgccgaccca ccacaccggt gccgcccggc ggaacgatca
    24421 cctacacctt ccgcttcaag gtctaccccg cggcactcgg taaggagcag cgccgggagg
    24481 cccgcgtcag ctccgaattc ccggcgacgg agccggacat caacgacaac acgaccacac
    24541 tggtggtcaa ggtcgccgac aaggcggcgc agccgaccgg caagcccacg tccccggcca
    24601 ccggcggcgc caagcccacc tcggcaccca ccacggcgcc cggcgaccat ctcgcggaca
    24661 ccggaggggc cggcaccggg tccgcgctca ccgcggccgg agcagccgcc gcggtcggcg
    24721 gcggcctcct gctgacctct cgccgtcggc gccgcagcca ctgaccccag gggaaaaagg
    24781 tgggggcggc gtctccgcac gagacgccgc ccccggtgag ggtggagatg gttctacggg
    24841 gtcaccggct gtcgttgccg gacgggtccg ccgccgcgcg gcccgcttcg aggcgggcca
    24901 ccgggatgcg gaacggggag caggagacgt agtcgagtcc gacctcgtgg aagaagtgga
    24961 cggactcggg gtcgccgccg tgctcgccgc agacgccgag cttgaggccg gggcgcgccg
    25021 cgcggccggc ttcgcaggcg gagcggatga gggcgccgac accgtcccgg tcgatggtct
    25081 cgaacgggga gacgccgaag atgcccttct ccaggtacgc ggtgaagaac gaggcctcca
    25141 cgtcgtcgcg ggagaagccc cacaccgtct gggtcaggtc gttcgtgccg aaggagaaga
    25201 actccgcggc ctcggcgatc tggcccgcgg tcagcgcggc acgcggcagt tcgatcatcg
    25261 tgccgagcgt cagcttgagg tttatgccgg tggcggcctc cacctcggcg atgaccttct
    25321 cggcctcctc gcggacgatc tccagctcct ggacggtgcc cacgagcgga atcatgatct
    25381 ccggacgcgg atcgcccttc atgttcttgc ggtgcgcggc cgcttcggcg atcgcccgta
    25441 cctgcatcga gaacagaccg gggatgacga ggccgagccg gacaccccgc aggccgagca
    25501 tcgggttctg ctcgtggagc ttgtggacgg cctgcagcag gcgcagatcg ttctcgttgg
    25561 cgtccttgcg ggactccgcg agcgccaccc gcaccgacag ctcggtgatg tcgggcagga
    25621 actcgtgcag cggcgggtcg aggaggcgca ccgtcaccgg caggccgtcc atcgcctcga
    25681 agagctcgat gaagtcggcc ttctgcagcg gcagcaaggc acccagtgcc tcgtcgcgct
    25741 cgctgtcggt gtcggcgagg atcagccgct cgaccagctc gcgccgctcg ccgaggaaca
    25801 tgtgctcggt acggcacagg ccgatgccct gggcgccgaa gcgccgcgcg cggttggcgt
    25861 cctcggcgtt gtcggcgttg gcccgtaccc gcagccggcg gacccggtcg gcgtaggcca
    25921 tgatccggtg cacggcctgg acgagttcgt cggcgtcgtc ggcgcccgcg tgcatccggc
    25981 cctcgaagta ctcgacgacc ggggacggga cgaccggcac ctcaccgagg tagaccttgc
    26041 cggaggagcc gtcgatggag acgacgtcgc cctcctcgat gacgatcccg cccggcgcgg
    26101 tcatccggcg ccgcttggtg tcgacctcca gctcctcggc gccgcacaca caggtcttgc
    26161 ccatgccgcg ggcgacgacg gcggcgtgcg aggtcttgcc gccgcgtgag gtcaggatcc
    26221 cctcggcggc gatcatgccg ttgaggtcgt ccgggttggt ctcgcggcgg atcaggatga
    26281 ccttctcgcc ggaccgcgac cacttgacgg cggtgtacga gtcgaagacg gccttgccga
    26341 cggccgcgcc gggcgaggcg gcgatgcccc agccgagccg cgtgaccttc gagtcctcct
    26401 cgaagcgcgg gaacatcagc tgcgcgagct gcgctccgtt gacccgctgc agcgcctcgg
    26461 cctcgtcgat caggccctgg tcgacgagct gggtggcgat ccggaaggcg gccgccgccg
    26521 tgcgcttgcc gacgcgggtc tgcagcatcc acagatggcc gcgctcgatg gtgaactcga
    26581 tgtcgcacag gtccttgtag tgcgtttcga gcgtcgtcat gatctgcatg agctggtcgt
    26641 acgacgcctt gtcgaggcct tcgagatcgg cgagcggcac ggtgttgcgg atacccgcga
    26701 cgacgtcctc gccctgcgcg ttctgcaggt agtcaccgta gacgccctgg tggccggtgg
    26761 ccgggtcacg ggtgaaggcg acgccggtgc ccgagtcggg gccgaggttg ccgaagacca
    26821 tggagcagat gttgacggcc gtgccgaggt cgccggggat gcgctcctgg cggcggtaga
    26881 gcttggcgcg gtcggtgttc cacgagtcga agaccgcgcg cacggcgagg tccatctgct
    26941 cacgcggctc ctgcgggaac tcgcggcccg tctccttgag cacgatgccc ttgaactcct
    27001 ccacgagctg ctggaggtcg gccgcgtcga gcccgaggtc gctctcggcg cccttggcgc
    27061 gcttgatctc ctcgagggcc tcctcgaaga gctcgccgtc cacgcccatg acggtcttgc
    27121 cgaacatctg cagcagccgg cggtaggagt cccacgcgaa gcgctcgtcc ccggcctggg
    27181 cggcgagccc ggccaccgag gcgtcggaca tgccgatgtt caggacggtg tccatcatgc
    27241 cgggcatgga gaacttggcc ccggaccgca cggacaccag cagcgggttg tccggctgcc
    27301 cgagcttctt gcccatcttc tgctcgaggg cgtcgaggtg cgcactcacc tcgtcgcgga
    27361 gctccgccgg ttcgtggccg gagtccaggt agaccttgca cgcctcggtc gtgatgacga
    27421 agcccggagg gacgggcaga ccgaggttgg tcatctcggc gaggttcgca ccttttccgc
    27481 cgagcaggtc cttgagttcc ttgttgccct cagtgaagtc gtagacgaac ttctgcgata
    27541 cctgttccga cacgggactc gactcctcgt gaggtccccc cggacagggt ctgggggagg
    27601 gatgccctga cggcggggag cgtacccatt cccaaggctt tgcagcacgt ccatcaccac
    27661 atcagacggc cgtaaccacc cgtctgccac tagatcgaaa gtaacgcgcc ccggtgatcc
    27721 acaccggatt ccgttcactt gtcgaatcga cgaccgcgca gcgtggtgcg atcacccatc
    27781 agagatcacc ctgcgtgaga aatcgttgat caagtggaga agccgggatg gcactgagtg
    27841 ccatcctttg gagagatgca gtcaggcatc cgcgctcatt tgagcgcaac ccccatcaaa
    27901 cgtggcgtga atcacgcggt cccggaggcc ccgctggacg ccccatctca cctttcggac
    27961 gtccgaggac ggcgaggacg tccggcgagg acgtcagccg cccgacgtgt ccagttcggc
    28021 ttccgggctg acggcggcgc agtcgtacgg gtcgttcagc cagccgtccg ggaggacgac
    28081 gcggttgttg cccgcggtgc ggccgcgcgg gccctcggcg ctctcgggcc agggctggtc
    28141 gaggtccacg gcggccaggt gctcgtccag ctcggcgagg gaggaagaga cggcgaggct
    28201 gcggcgcagc tgggagccga ccgagaagcc cttggtgtac caggcgacgt gcttgcggaa
    28261 gtcgatcact ccgcgctcct cgtcgccgat ccactcgccg agcagctcgg cgtgccgccg
    28321 catgacgacg gcgacctcct tgaaggtcgg ccgggcctgg gcgtccccgc cctccatggc
    28381 gctgaccagg tcgccgaaga tccaggggcg gccgaggcag ccgcggccga ccacgacgcc
    28441 gtcggcgccg gtctcgcgca tcatgcgcag cgcgtcgtcg gcgcgccaga tgtcgccgtt
    28501 gccgagcacc gggatctccg ggacgtgctc cttgaggcgg gcgatggcgt cccagtcggc
    28561 ggtgccgccg tagtgctgtg cggcggtgcg gccgtgcagg gcgaccgcgg tgacgccctc
    28621 ctcgaccgcg atccggcccg cgtcgaggta cgtcaggtgg tcgtcgtcga tgcccttgcg
    28681 catcttgatg gtgaccggca ggtcgcccgc gttgccgacc gcctcgcgca ggatggagcg
    28741 cagcaggttc cgcttgtacg ggagggccga gccgccgccc ttgcgggtca ccttggggac
    28801 cgggcagccg aagttgaggt cgatgtggtc ggccaggccc tcgtccgcga tcatgcggac
    28861 ggccttgccg acggtcaccg ggtcgacgcc gtagagctgg atggagcgcg gcttctcggt
    28921 cgcgtcgaag cggatcagcc gcagcgtctt ggagtcccgc tcgacgaggg cgcgggtggt
    28981 gatcatctcg ctgacgaaca accccttgcc gccggagaac tcacggcaca gcgtgcggaa
    29041 gggcgcgttg gtgatgccgg ccatgggggc gagcaccacg ggcggccaca ccgtgtgcgg
    29101 gccgatctga agtggcatgg tggcgtcagc ggtcatggcc ccattgtcgc gtacgccgga
    29161 cggggatttc gatgtaccgt tcacgtatat gtgtgccctt ggccacgagg gcggagaacg
    29221 gccgatccca ggaggcccaa gtgccggaac tgagcccccg gcgccgcatg ctcgtgctgg
    29281 cgatctgctg catgagcctg ctcatggtca gcctcgacaa caccatcctc aatgtggcgc
    29341 tgccctccct gcagaaggaa ctgcacgcct cggtctccgg tctgcagtgg acgatcgacg
    29401 cgtacacgct ggtgctggcc tcgctgctga tgctggccgg ctcgacggcc gaccggatcg
    29461 gccgccgccg ggtcttccag accggtctgg tgctcttcac cgcgggctcg gtgctctgca
    29521 gcctggcgcc cagcctcaac tggctggtcg tcttccggat ggtgcaggcg gtcggcggct
    29581 cgatgctcaa ccccgtcgcg atgtcgatca tcaccaacac cttcaccgac ccccgggagc
    29641 gcgcccgcgc gatcggggtg tggggcggcg tcgtcggcgt cagcatggcg gcgggcccgg
    29701 tgctcggcgg actgctcgtg cagaccgtcg gctggcgttc catcttctgg atcaacctcc
    29761 cggtcggact gctcgcgctg gccctgaccg cccgctacgt gcccgagtcg cgcgccccca
    29821 agccgcgccg ggtggacccg gtcggccagc tgttcgtcat cgccctgctc ggctccctga
    29881 cgtacgcgat catcgaggcg ccggacgcgg gctggacgtc ggcgctgatc ctcggctgcc
    29941 tggcggtcgc catcggctcg ctcgccgggc tgctcagcta cgagcggcgc cgcgtggacc
    30001 cgctgatcga gctcggcttc ttccgtagcg cgcccttcag cggcgcgacg gtcatagcgg
    30061 tgagcgcgtt cgcggcgctc ggcggcttcc tcttcctcaa caccctgtac ctgcagaaca
    30121 cccgcggtct ctccgccctc gacgccgggc tctacatgct gccgatggcc gtcatgtgcc
    30181 tggtcttcgc cccgctgtcc gggcggctgg tcggcaaccg ggggccacgg ctgtcgctgg
    30241 tgctcgcggg tacggcgatg acgatcagcg gtgtgatgtt cgcggccctg gacgccgagt
    30301 cctccaacac actgctgttc acctcgtacg tcctcttcgg catcgggttc ggtctggtca
    30361 acgcgccgat caccaacacc gccgtgtccg ggatgccgcg ctcgcaggcc ggggtggccg
    30421 ccgccgtcgc ctccaccagc cgccaggtcg ggcagtcgct cggggtcgcc gtgatcggcg
    30481 ccgccatcgc cgccgggctg cacaccaccg cctggtggat catcgcgggc tgcggcgccg
    30541 tcgtcctgct cctcggcacg ctgaccaccg gccgctgggc cgccgggacc gcggaacggg
    30601 ccgcggcgcg gttccgggaa ccggcgcccc tgaccgtcgg gaccgaagcg gtcacgaact
    30661 cctgactacg accggcccgc cgacgcgaga acgggccgcg cgtcactcgc ggcagggccg
    30721 cacagctcgt acagccgctg cagccgggta cgcgtcacct cgtccgccgg ggtgtacgtc
    30781 acgagccgcg gcccggagcg cgggccgagc cacagatggg tgaagtcgaa ggtgagcagc
    30841 ccgacctgcg ggttcagata gcgcttggag cggttgtccg gctggagcac ctcatggcgg
    30901 tcccacgcct cgcagaactc cggtgacgcc tgctggaggc gcttgaggag cgacttccag
    30961 gccggctccg ccaggtgctc ggccatcgcc gaccggaatt tggcggccat cagccggatc
    31021 acctcttccc ggtcgatcag cgcctcgcgc caggccgggt cggtgaaggc gagccacatg
    31081 atgttgcggt cctcgaaggg ccgcgcgtcc agatcgtcga ccagccgccc gtaggtgcgg
    31141 ttgtacgcga tcacgtcgtg ccggctgttg gcgacgaagg cgggcagcgg ttccagctgc
    31201 tccagcatca gacggatctg gtccgacatg ccggggcagt ccgcgaaggg gctggggtcg
    31261 gcgaccccgg cgagggtgaa caggtgcacg cgctcgttcg gatcgagcat cagggcgcgg
    31321 gcgatcgcgt ccgcgacctg cgcggacacc tggatgtccc gggcctgctc cagccacgtg
    31381 taccaggtga cgccgaccgc ggcgagcccc gcgacctcct cgcggcgcag cccgggcgtg
    31441 cggcgccgcc gccccgccgg cagtccgacc tgctcgggag cgatgcgctc gcggcggctg
    31501 cgcaggaacg aggcgagctc gcgccgcttg atgtcggcgt ccgactcgtg ctgcgcgggg
    31561 ggcgtcgtcg taggcatgct tccagcatgc cggatcgcgg agccagttgc gtggtggttc
    31621 ttatacctgg ataaacgctc tctggtacca ccctgaaaac cggcgcatgg ttgctcacgt
    31681 gaccccaatg gaacgtactc ccgtcctccc ctcccgcgcc ctggtcctgc cccgggtgac
    31741 gcgcatcggc actcccccgg ccaccacggg ccccgccgct ccggccggtc ctgtactgac
    31801 cgcactcggc ctgttcaccg tgctgctcgg cgcggccctg ccactgatcg acttcttcat
    31861 cgtcaacgtc gcgctgccga ccatcgaccg cgacctcgcc gccggaccgg ccctgctgga
    31921 gctggtggtg gccggctacg gcaccgcgta cgccgtgctc ctggtgctcg gcgggcggct
    31981 cggcgacatg ttcggccgcc gccggctctt cctcgccggg atggccgcct tcggcctgac
    32041 ctcgctggcc tgcggcctcg cgccggacgc ctggacgctg gtcggcgccc gggtggcgca
    32101 gggcgccgcg gccgcgctga tgctccccca ggtgctcgcc accatccagt cctccaccgc
    32161 aggaccgcgg cgcgcccgcg cgctcagcct gtacggcgcc acggccggcc tgtcgatggt
    32221 cgccgggcag atcctcggcg gcgtcctggt ggccgccgac atcgcgggca ccggatggcg
    32281 cgcggtgttc ctggtgaacg tgccggtcgc cctgatcggc ctggtcctgg cggcccgcac
    32341 catccccgag acccgctccg agcgccccac cccgatcgac gtcccgggca ccgtcctgct
    32401 ggccgtctcc ctggtgacgc tgctggcgcc gctgaccgag ggccgcgcct ccggctggcc
    32461 gctgtggacc tggatctcgc tcgccgcctt cccgttcgcg gcctacgcct tctacgcggt
    32521 cgagcgccgc gcggaccggc agggccgcac cccgctggtg ccgccgagcc tcttccaact
    32581 gcccggcatc cggcgcggac tgccgctcgt cgtcccgttc tccatcggct tcggcggctt
    32641 catgctggtg atggcggtgg ccctgcagca gggcctggcc ttcggcccgg tcgcggccgg
    32701 catggcgatg gcgccgctcg ccgtcacgtt cttcgccgcc tccctgatgg gcccgcgcct
    32761 ggtcgcgcgg tacggcagcc gggtggtcac ggtcggcggc ctgatccagg cactcggcct
    32821 cctcctcctg gtcgccgcgg ccctgcacga ctggcggcac ctgaacggcc tctccc
//
