LOCUS       NZ_CP048835            41185 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 365606
            Orig. end                         :: 406791
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="2"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41185
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41185
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21185](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21185)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    complement(559..573)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.31"
                     /tool="antismash"
     gene            1021..1560
                     /locus_tag="C8250_RS01755"
                     /old_locus_tag="C8250_001755"
     CDS             1021..1560
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997519.1"
                     /locus_tag="C8250_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001755"
                     /product="hypothetical protein"
                     /protein_id="WP_138351767.1"
                     /transl_table=11
                     /translation="MSERSTALRQIRAWLVLFIVCLALSGLTAFPLVHELRWADSLLGS
                     TALGDWFPGLTRWITRVRTGLDTADADYPFLLYGTDWLAFAHLVIAVAFYGPYRDPVRN
                     IWVVEFGMIACAGIIPLALICGPVRGIPLWWSVIDMSFGAFGVIPLYVVRRKIQRLAAL
                     DDAAGPRPAAVAQPAQ"
     gene            complement(1650..2489)
                     /gene="nadE"
                     /locus_tag="C8250_RS01760"
                     /old_locus_tag="C8250_001760"
     CDS             complement(1650..2489)
                     /EC_number="6.3.1.5"
                     /GO_function="GO:0003952 - NAD+ synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0004359 - glutaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008795 - NAD+ synthase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nadE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004938865.1"
                     /locus_tag="C8250_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001760"
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="WP_138351768.1"
                     /transl_table=11
                     /translation="MTVPAPIGLQQEIARDLHVAAIFDAEVEIERRVAFLAERLTTTGL
                     RSLVLGISGGVDSTTAGRLCQLAVERARRAGHDATFYAMRLPYGVQADEQDAQLALDFI
                     RADQVLTVNVKAASDAALEACLAGGVAFRDERHQDFVHGNIKARQRMIAQYAVAGAHEG
                     LVVGTDHAAEAVSGFFTKFGDGAADVLPLAGLIKRRVRAVGEALGAPASLVWKVPTADL
                     ETLDEGKADEDALGVTYDEIDDFLEGKPVSERAFASIVGRYQGTEHKRQLPVTPPQG"
     gene            2803..3108
                     /locus_tag="C8250_RS01765"
                     /old_locus_tag="C8250_001765"
     CDS             2803..3108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891824.1"
                     /locus_tag="C8250_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001765"
                     /product="hypothetical protein"
                     /protein_id="WP_138351769.1"
                     /transl_table=11
                     /translation="MKRVIRGLGAAAVTAVFAGGLLVALPGAASANDYGYTCKNWKDTS
                     HSWSADCHVTRGKARTVTECANGKTYYGKWVGSGYWKFDGECGKYALMATDIQWKK"
     gene            complement(3239..3862)
                     /locus_tag="C8250_RS01770"
                     /old_locus_tag="C8250_001770"
     CDS             complement(3239..3862)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_001770"
                     /product="hypothetical protein"
                     /protein_id="WP_138351770.1"
                     /transl_table=11
                     /translation="MTADAVALTRRSLHGIAELVLAGPQHREIGRIRLRIVGGGFGTIG
                     EPALRVEGGDLVSGTARIALSGQTYAALAEAAGIEAGAPEGLYPDGSGVKPDEVITVDP
                     EAGAEILRAFAAGDEALRGFAPETEPVLWPEHFDLAITLDEVNYGVSPGDDHLPEPYAY
                     VGPHRPREGKFWNAPFGAARALRELGNADAIQGFFEEGKRRTDS"
     gene            complement(3978..4400)
                     /locus_tag="C8250_RS01775"
                     /old_locus_tag="C8250_001775"
     CDS             complement(3978..4400)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971505.1"
                     /locus_tag="C8250_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001775"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_138351771.1"
                     /transl_table=11
                     /translation="MPTSEAAAIAAELRTAMGKLTRRVKHEDRIPLGQVAVLGALDRDG
                     AMTTSDLAADQRVRPQSMARSVGLLMEQDLITRRAHPTDGRKSLVELSDAGRAALEAER
                     GRRVGWLAQAIEAELTDEEQTLLARSATLLERLATR"
     misc_feature    4454..4472
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.03"
                     /tool="antismash"
     misc_feature    4459..4475
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.46"
                     /tool="antismash"
     gene            4564..5871
                     /gene="eno"
                     /locus_tag="C8250_RS01780"
                     /old_locus_tag="C8250_001780"
     CDS             4564..5871
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575746.1"
                     /locus_tag="C8250_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001780"
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_138351772.1"
                     /transl_table=11
                     /translation="MSAQASGTVNAAIETVTARRIIDSRGNPTVEVDVVLADGSLGRAA
                     VPSGASTGAREAVELRDGDPARWHGKGVDRAVAHVNGEIAATVRGRDAADQAGLDAALV
                     ALDGTATKSRLGANAILGVSLAAAKAAAAAHRRPLYRYLGGAGAHLLPLPMMNIVNGGA
                     HADNPLDFQEFMIAPVGAETFAEAVRMGSEIFHTLRRDLLAAGHSTGVGDEGGFAPALR
                     TAEEALDFVMTAIERTGYRPGTDIGLIMDPASSEFFRDGVYDYAGEGVRRTPSENADYL
                     AKLIDAYPIVSVEDPMAENDLDGWRELTARVGDRCQLTGDDVFCTNETLLREGIRTGVG
                     NSVLVKVNQIGTLTEALATVATAHQAGWTVVMSHRSGETEDTTIADLAVATGCGQIKTG
                     SLSRSDRTAKYNQLIRIEEELGDSARFAGRSALRRA"
     gene            complement(6010..6579)
                     /locus_tag="C8250_RS01785"
                     /old_locus_tag="C8250_001785"
     CDS             complement(6010..6579)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563802.1"
                     /locus_tag="C8250_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001785"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_138351773.1"
                     /transl_table=11
                     /translation="MPNPTPTRERIVEATLRIIGQDGVAAVTNRRIAKEAGVSLGSITY
                     HFATQHDLLRESLRSFVDQETRRFTDLAARHITDCVTAEQAATIVGQVSADTAFDSEHI
                     APFELYIHAGRDPQLRPAAAECFTAYDQLAASILGGLGVPDPERLAGPVVALVVGLQLR
                     RLATGSASDDLVTALLLLTGGSTPGP"
     gene            complement(<6718..7011)
                     /locus_tag="C8250_RS01790"
                     /old_locus_tag="C8250_001790"
                     /pseudo=""
     CDS             complement(<6718..7011)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563801.1"
                     /locus_tag="C8250_RS01790"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001790"
                     /product="amidase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MADSARTGLAAQSAALHGGHISSRVLVEESLARIEATQPTVNAFR
                     RVRATAALAEADAADRRLAAGHRLPLLGVPIAVKDDTDVAGEPTAFGCAGDFP"
     gene            7075..7866
                     /locus_tag="C8250_RS01795"
                     /old_locus_tag="C8250_001795"
     CDS             7075..7866
                     /NRPS_PKS="Domain: PKS_KR (6-166). E-value: 1.5e-16. Score:
                     52.8. Matches aSDomain:
                     nrpspksdomains_C8250_RS01795_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268169.1"
                     /locus_tag="C8250_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001795"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_138351775.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-32, bitscore:
                     111.8, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDINGSTVLLTGAGGGIGHALAKALAAKGAHLVITGRRAESLKGL
                     EASLGARVLVADLSDRDAVVRLAEEAGPVDILVANAALPASGALLDFTPAEIDRSLEVN
                     LRAPLMLSRLLAPHMVAAGRGHLLMIGSISGRTSSPATSLYSAAKFGLRGFAHALRQDL
                     HATGVGVSIVQPGFVRGAGMFADTGATPPAGVRTVTPERVAAGAVSALERDRAEVNVAP
                     VELRLGSAIGSLFPSLGAAVQRRAALESFIGQITQAQRHKR"
     CDS_motif       7093..7188
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS01795_0001"
                     /evalue="6.50E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS01795"
                     /protein_end="38"
                     /protein_start="6"
                     /score="25.2"
                     /tool="antismash"
                     /translation="TVLLTGAGGGIGHALAKALAAKGAHLVITGRR"
     aSDomain        7093..7572
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS01795_PKS_KR.1"
                     /evalue="1.50E-16"
                     /label="C8250_RS01795_PKS_KR.1"
                     /locus_tag="C8250_RS01795"
                     /protein_end="166"
                     /protein_start="6"
                     /score="52.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TVLLTGAGGGIGHALAKALAAKGAHLVITGRRAESLKGLEASLGA
                     RVLVADLSDRDAVVRLAEEAGPVDILVANAALPASGALLDFTPAEIDRSLEVNLRAPLM
                     LSRLLAPHMVAAGRGHLLMIGSISGRTSSPATSLYSAAKFGLRGFAHALRQDLHAT"
     CDS_motif       7411..7467
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C8250_RS01795_0002"
                     /evalue="5.90E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="C8250_RS01795"
                     /protein_end="131"
                     /protein_start="112"
                     /score="6.1"
                     /tool="antismash"
                     /translation="RLLAPHMVAAGRGHLLMIG"
     gene            7972..8427
                     /locus_tag="C8250_RS01800"
                     /old_locus_tag="C8250_001800"
     CDS             7972..8427
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383220.1"
                     /locus_tag="C8250_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001800"
                     /product="DoxX family protein"
                     /protein_id="WP_138351776.1"
                     /transl_table=11
                     /translation="MSQAALPTTTATAATDTSRTAAAPGRKARIALRTLQVVLALFFIV
                     ASGLPKLFAASAAAESFDKIGFGDWYMYFVGSLEVAGGIALLIPVLSGIAATAFIGLMI
                     GAFITNVTALDGHYAATPLILIIPFALIAWARRHHNAELLQLVRHRA"
     gene            complement(8530..11316)
                     /locus_tag="C8250_RS01805"
                     /old_locus_tag="C8250_001805"
     CDS             complement(8530..11316)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="C8250_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001805"
                     /product="protein kinase"
                     /protein_id="WP_187144693.1"
                     /sec_met_domain="Pkinase (E-value: 4.3e-44, bitscore:
                     149.8, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWIGKRRNGTPESGDPAAEVLARLREGSASAEQDGREGRPGKAV
                     KRYRELVVRATAAPGPDDPATLAMRHQLAHWTGESGDAEGAVRLFAQLLSDRERLQGSR
                     HQDTGLARHQLAHWHGRAGRADEAVRRYEELQRSAEQEGRTEAALNLLCDMGHWQQQAG
                     DNAAALRTYTRMLKTAENELGGRHALTGIARQRYAELAGGLPFGHERGHDSLQDLVAAA
                     AEVERSGDLSRASRMYGQIADKCAQLYGAGSDRRLGALVSQAKAAMRTEDLDEAVVCFG
                     RVLACMELRGEGPGSPEYDVLSEQRDGLARSTRETTLHIGDTAGTLLARQVEAAPATAF
                     GLLARENRARHLTRVFPVSDGTDDPQPHKVSIEQWLGVIQRLADQGCEARSFYFARADR
                     RPTPEEIALCARLGLLGVYVSNEGAGNVNVEAYSFRGGTPQVVSIVVVDEEQAAPEPAP
                     ARGPGGATAVHAEAEALGEWRQVGRATSARTAEDPAAFGSYEVLERVGEGGFGRVYLCQ
                     DPDGVMVAVKTLHAEYAADSSIREGFTHEVQAARRVSGRFTVPVIAADTSGGTPWMAVP
                     FVAAPSLQEVAERCGALDAATVRGIGAGIATALTAIHAEGIVHLDLKPANVLLTEDGPR
                     VIDFGIAQIERLTEPRSGFAGTYAYASPEQIREHEQFTPASDVFSLGTLLARLALGRLP
                     WGRKVLAVMTNICDGTPDLAGLPAELEEVVRSCLQTDPARRPTPAAVAAALAAGSAGAP
                     LGPEVERFAPPPLPAEATTIIREHATLPATRHFETLVHTRVARPDDTTVAARPTMGGDT
                     SDTPREDRTPDTAAQDLEAQVLAWEREGGSKPTGQVRRECGAFAAEARSRLGEDHPLAL
                     RLKVSHAMLGYDGTDGTDGTAYAERVVDEAAVRLGDGHPTVRDARTLLAALRSAPPG"
     gene            complement(11443..12243)
                     /locus_tag="C8250_RS01810"
                     /old_locus_tag="C8250_001810"
     CDS             complement(11443..12243)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_001810"
                     /product="hypothetical protein"
                     /protein_id="WP_138351778.1"
                     /transl_table=11
                     /translation="MTTMRIGAERAAGGSPSSRRGAGRNRLVGAALIVLSLVSALTCAF
                     VFTSWLPTDGALYREYRAAEVCSVRTVIPASEDCLRELSFTVEGTHKTAKNMRATLLGP
                     RPFGRVVVSFSDSGPTLSGLQKGDRVTATVWRGVVVMVAEGDARQHSADAPRDEPQMTA
                     AVGTFAGLLAALAFMFGAMHLVRPRDPGLFTWRPYGKWLLIVTGATCVVVGLGTVWTGL
                     PWLLVPTVCGVVVAGTAWLLHRDLRLGRANAASRPAQHLSRQAQ"
     gene            12667..16356
                     /locus_tag="C8250_RS01815"
                     /old_locus_tag="C8250_001815"
     CDS             12667..16356
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014133573.1"
                     /locus_tag="C8250_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001815"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_187144694.1"
                     /transl_table=11
                     /translation="MGRDAAGGEALSRGLLFIPIATALIQDDGRIIHWSADAEVLLGYT
                     AEEAVGAFASHLLVDVEQQPRVMDLFAGILGGEAWSGVFPVKHRDGHSVNLEFRTHPIP
                     TESGRPLVLAVASDVREIRRIESDLAVLDSFFTQSPVGMAVYDTDLRFVRLNDALARIN
                     GLPADQHLGRRLTEVLPGLNGEEIEAVMRQVLETGEPVVDARSHGITPADPSKERAWSA
                     SYFRLEERTGRILGVSSTIIEVTERFQAESRAATARERLEVLVDATSRIGTTLDLGRTA
                     QELADTMVPRLADVSGVFVLERLITGQNADSSAPDGAEQVRRLAIASSDPGYPVRDLPV
                     DAVHRVPRDSPYAEAMATHRTVIVPSVDLPPLAPVEAAERVHAYQTRVSRTVRVTPLVV
                     RGAVLGMVVYSRRGGMEAFGEDDVTLGDELTSRAAVAVDNALLYRREHETGESRQQALR
                     QANAARERLALINAASARIGTTLDLTQTARELAEVATPTLADTVVVEVVDALLRGEEVP
                     GPPDRSALLRRLAFHTTDGAGMVPVAPVGDVHRFHPTTPYAWSLAHRRPVLVPRMDEEG
                     LSWFAEDPIRNAASREQGLRSFMVVPLIARDAVVGVVSFYRTITDRPYDEEDLALAGEL
                     AARAAVSIDNALLYTRERDASKARQQALEEAHAAQERLALLNDASSRIGTTLDLQRTAE
                     ELVELVIPRFADFATVDLLESVVQGGDEEGDQTTSPTDGRVLLRAVAVGEVNESGMIGA
                     ADEVGGTSRSAKLYAESLRTGRSILVAQVDEAALRRIVAHPDRVQPGLDAGVHSYLMVP
                     LPARGVVLGGAEFIRMRNPEPFTVADVALAEELAARAAVCIDNARLYRRERDTVLTLQR
                     SLLPQEVHLTPGLEIAYRYLPSSVVSEVGGDWFDVVPLSCGRVALIVGDVMGHGIRAAA
                     TMGQLRTAARTLITLDMSPDRVLRRLDETASAIGDGQFTTCVCAVFDPVDRSCIIACAG
                     HPPPVVQDPNGSTRLIDLPPGVPLGVGGVAFENVEITLPEDGVLVLYTDGLIERRDRDL
                     DEGMLLLSQAVANRGPSLEASCDAVLDALSAKDSEDDIAIIMARAMPVRDDWIAMLPLS
                     GDMAVVGEARRFTRARLCSWGLQSLSEVAELLVSELVSNALLHTGMPTELRLFRDRVLT
                     LEVADTDNQVPRVRRVSEEDEGGRGMHLVNELAHRWGSRATRHGKVVWIELELPLGTFT
                     PGGP"
     gene            16583..17530
                     /locus_tag="C8250_RS01820"
                     /old_locus_tag="C8250_001825"
     CDS             16583..17530
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013434.4"
                     /locus_tag="C8250_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001825"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_198358507.1"
                     /sec_met_domain="DAO (E-value: 1.4e-38, bitscore: 132.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKRVNVVGAGIVGLSIAHDLALRGHAVTVIADQRAEESVSSVAA
                     AVWFPYRSGTSPSLMGWLLAARARFEQLSTDRAAGVDLREGLVVERHVGEDRSWTDAVP
                     LHHEAAADELPSGAVAGVRATVPVISMPHYLPWLEKRCTGLGVTFVERKVTAVDDLAGD
                     ADLVVVAAGMGSGALLDDDSMYPVQGQIVRLANPGITEWITDTENPGGLTYIVPRREDI
                     VCGGVAQVGSWATEPVAEIEQAILRRVVSLMPALAGLPVLSRATGLRPARDTIRLEHVD
                     GFPVPVIACYGHGGAGVTLSWGCAEAVADLADQI"
     misc_feature    16585..16600
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            17804..19978
                     /locus_tag="C8250_RS01825"
                     /old_locus_tag="C8250_001830"
     CDS             17804..19978
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971925.1"
                     /locus_tag="C8250_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001830"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_138351781.1"
                     /transl_table=11
                     /translation="MDSTSSPLPSSPFEQVSRALGDYIPRDGPAAAADPAAPQGDHSDP
                     RSPNGDRATTGQEQILGAVNLDRELRITRCNLDAPAFDGLGVTVGAAFADLLPPGDIPT
                     VIRRLRQVIETGEAHVARVQRLRRDDGSELVVSMSILPAAAPQEGLTVSLIAMAKRLHL
                     YASETAIGTSLDIGETAQSLAQSLLVWGDVAAVDLDYAVWTGEAVTEQAQGRIRLRRAA
                     LMPDRAWPEGYLTPGDNLPNEASRLLSLAVTRDDVAQALVIPDREAIERVLGDPRLVRA
                     LVPVDRPASVACIPLVLEGSDGAPPIVLGVAEVWRRPDRPFHDSELLDLQELVARTAHH
                     VDLARQHQREHAQVLALQRRLLPRAGSDTIEVASVYQPTTPDSAGVGGDWVNSFPLPDG
                     RTALVVGDVVGHGLGAAAAMGQLSMEARALLSAGLAPDEVLAHLDETVTLLDDADAGLA
                     AGYSALGSTCCIAVYDPVGHQVVTSSAGHLPPILVLPDGSARTLATHPHPGLGTAFALR
                     EPFDVHTFAAPPGSLLALYTDGLVEDPAVSIDEGIDRLTDAVSKVHPWDDLQQVARSLV
                     VEFASRSRLRDDVTLLLARMAGRRKRDTAAWRLPARDDAAARARTLASAVLRQWHAKSA
                     PRDSALLVISELVTNAVRFATGPITVRLIKTGHSLLCEVGDTSNGRPRLGRGGLLDDSG
                     RGLRVVHKLTTRWGVRWTDTGKVVWAELAR"
     gene            complement(20001..21185)
                     /locus_tag="C8250_RS01830"
                     /old_locus_tag="C8250_001835"
     CDS             complement(20001..21185)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031521.1"
                     /locus_tag="C8250_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001835"
                     /product="type III polyketide synthase"
                     /protein_id="WP_138351782.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2e-16, bitscore:
                     59.1, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAYLCPPAVIHGEHAVETSQILAEVRDRHQHAPWLPRIDGIAAS
                     TGIASRGWMVPLATAVASSAGSGLRTPGVAPARQALIRDGFSEQEVDRAISALEAIPAP
                     QTVQERTAPAWEAVQAYGERAARGALQIAGLDAADVDCLITSHSTTPALPGLDIAVADR
                     LSLRDDALLLPATQWACIAGTRSLALAADLVAADPDRVVLVVISEALSTTYQPADDTLE
                     SLIVRLLFADTAVAAVVTGRPRPQSVLRLDAAWHHTLPGTRDLHRLDTRADGTHFVMDR
                     RGPRAVQDTVVAMWEWLRLRHQDDANPWHPDLLLAHPGGTRVLEYMEQTMPDGWPTDVL
                     AYSRDSYTSGNRGGAAVFDILRRAHDAGQSAGSRTVLFAAAPGLTATAVEAEWL"
     misc_feature    complement(21335..21350)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    21725..21742
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            21751..>22236
                     /locus_tag="C8250_RS01835"
                     /old_locus_tag="C8250_001840"
                     /pseudo=""
     CDS             21751..>22236
                     /GO_function="GO:0070573 - metallodipeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890046.1"
                     /locus_tag="C8250_RS01835"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001840"
                     /product="membrane dipeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFEELHRRAVVADAHNDLLTAVAARPPKRWGSFFRERWLPQLQAG
                     GIDLQVLPVFIDAPYQPEGALRQTLRMIECVHVRAEENADQVALCLTGADIDAALVQDK
                     LALVLALESAPGVGASTELFSTLHRLGVRIASIAHWGRTPLADGSREDATGSRLTAPG"
     gene            complement(22350..23639)
                     /locus_tag="C8250_RS01840"
                     /old_locus_tag="C8250_001845"
     CDS             complement(22350..23639)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430094.1"
                     /locus_tag="C8250_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001845"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_138351783.1"
                     /transl_table=11
                     /translation="MDELHDIGSWLRERLPQLLAEHGVPGAAVAIGAGAKTVEVAAGVL
                     STATGVEATVDSVFQIGSITKVLTATLVMQLVGEGRVALDAPVRTYLPGFREATVRQLL
                     CHTSGFEGDVFTDTGKGDDCLATYVDLLDEVPQNFEPGMMFSCNNAGYCVLGRIVEVVR
                     GKPFDACMRDHLFTPLGMTHAANDPYEAIVHRAVVGHLDGKPSAVWAMARSNAPAGSML
                     AMTPRDLLAFARTHLAEDDLQAMRQPQVALPDIGWGTAWGLGWELYGLPGGLVFGHDGN
                     TIGQSAVLRVVPGRDLAVAIFTNGGDPKPLRKEILGRILELPGDPVPDPAVRLNARRCV
                     GTYLSSTGETRVGEDEQGRLWLEHVPLGITAELGDESYRTELVAWRGDSLLPVEPGHGP
                     VAFLGDDGEGRARYLHTGRADVRSSGRTRG"
     misc_feature    23726..23739
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.64"
                     /tool="antismash"
     gene            23881..24909
                     /gene="tdh"
                     /locus_tag="C8250_RS01845"
                     /old_locus_tag="C8250_001850"
     CDS             23881..24909
                     /EC_number="1.1.1.103"
                     /GO_function="GO:0008743 - L-threonine 3-dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006567 - threonine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="tdh"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004922312.1"
                     /locus_tag="C8250_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001850"
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="WP_138351784.1"
                     /sec_met_domain="ADH_N (E-value: 6.1e-31, bitscore: 105.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.2e-21, bitscore:
                     74.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVKAKAEPGLWLMDVPEPEVGPGEVLIKVLRTGICGTDLHIR
                     DYDGWAQQAVRTPLVLGHEFVGEIVEVAAGVADLAPGDLVSGEGHLICGKCRNCLAGRR
                     HLCRSTVGLGIGRDGAFAEYVTLPATNVWVHRVPVDLDVAAIFDPFGNAVHTALSFPLV
                     GEDVLITGAGPIGIMAAAVARHAGARQVMITDVSPFRLELAEKVGVSLALDVSSSTIAD
                     GQRRLGLREGFDVGLEMSGRPEALRDMIANMTHGGRIAMLGLPAEEFPVDFARIVTSMI
                     TLKGIYGREMFETWYAMSVLLEGGLDLSPVITGRYSYKDFDAAFDDAAGGRCGKVILDW
                     TA"
     gene            24986..26194
                     /locus_tag="C8250_RS01850"
                     /old_locus_tag="C8250_001855"
     CDS             24986..26194
                     /EC_number="2.3.1.29"
                     /GO_function="GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (45-392). E-value:
                     3.5e-70. Score: 228.9. Matches aSDomain:
                     nrpspksdomains_C8250_RS01850_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386190.1"
                     /locus_tag="C8250_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001855"
                     /product="glycine C-acetyltransferase"
                     /protein_id="WP_138351785.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.5e-68, bitscore:
                     228.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDAVREDLRATLDEIRSAGLHKPERVIGTPQSASVDVTAGGRPG
                     EVLNFCANNYLGLADNPEVVAAAKSALDRWGYGMASVRFICGTQEVHKELEARLSRFLG
                     MEDTILYSSCFDANGGVFETLLDERDAVISDALNHASIIDGIRLSKARRFRYANRDMAD
                     LEQRLKEAAGARRTLVVTDGVFSMDGYVAPLEEICDLAERYGAMVMVDDSHAVGFVGPG
                     GRGTPELHGVMDRVDIVTGTLGKALGGASGGYVAARAEIVELLRQRSRPYLFSNSLAPV
                     IAAASIKVLDLLEDDTTGEGAALRARLYANTELFRRRMTEEGFEILPGDHPIAPVMIGD
                     AEQAGRIADQLLEHGIYAVGFSYPVVPHGKARIRVQLSAAHSAPDVERAVAAFSAARAA
                     LAE"
     aSDomain        25121..26161
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C8250_RS01850_Aminotran_1_2.1"
                     /evalue="3.50E-70"
                     /label="C8250_RS01850_Aminotran_1_2.1"
                     /locus_tag="C8250_RS01850"
                     /protein_end="392"
                     /protein_start="45"
                     /score="228.9"
                     /tool="antismash"
                     /translation="EVLNFCANNYLGLADNPEVVAAAKSALDRWGYGMASVRFICGTQE
                     VHKELEARLSRFLGMEDTILYSSCFDANGGVFETLLDERDAVISDALNHASIIDGIRLS
                     KARRFRYANRDMADLEQRLKEAAGARRTLVVTDGVFSMDGYVAPLEEICDLAERYGAMV
                     MVDDSHAVGFVGPGGRGTPELHGVMDRVDIVTGTLGKALGGASGGYVAARAEIVELLRQ
                     RSRPYLFSNSLAPVIAAASIKVLDLLEDDTTGEGAALRARLYANTELFRRRMTEEGFEI
                     LPGDHPIAPVMIGDAEQAGRIADQLLEHGIYAVGFSYPVVPHGKARIRVQLSAAHSAPD
                     VERAVAA"
     gene            26199..27146
                     /locus_tag="C8250_RS01855"
                     /old_locus_tag="C8250_001860"
     CDS             26199..27146
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563051.1"
                     /locus_tag="C8250_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001860"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_138351786.1"
                     /transl_table=11
                     /translation="MIDTRRLRTLRAVADHRTLTAAAAALYLTPSAVSQQLAALEQEVG
                     HQLLVRDGRGVRLTAAGEILAAHGNTVLAQLERAEAELAAYAAGHAGEVTVASFATGIA
                     TVVAPAMTELGTSHPGIRLRVRDAEGDASLTMVLDGHADLAVAVEYRGAPREDDERLSR
                     VPLYAEPFDAVLPRSHRLADSASVRVADLAEEPWIGPYPGNPCHEVVMLACEFAGFQPR
                     VTHSSDDFRAVAALAGAGAGVALVPRSALRGVDLPEVVVLPVAGDPPTRRVFAAVRRGA
                     EQHPLVRPVLDALAMAADRARPREDPAELLGLNG"
     gene            27244..28170
                     /gene="bla"
                     /locus_tag="C8250_RS01860"
                     /old_locus_tag="C8250_001865"
     CDS             27244..28170
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050093.1"
                     /locus_tag="C8250_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001865"
                     /product="class A beta-lactamase"
                     /protein_id="WP_138351787.1"
                     /transl_table=11
                     /translation="MPYTRARRAVLGGLAVLTVLPLAACGSGDTPASPAPSTTASRPDP
                     AGKPSAGDFQRLERTYDARLGIYAVNTGNGREVAYRDTERFAYASTFKAFAAAAVLRKY
                     SLNGMGKVVKYSRADLLSNSPVTAKHVETGMTLRELCDAAVRYSDNTAANLLFAALGGP
                     KGLAAALAEAGDTATRVERREPELNEWTPGATRDTTTPRAWAANLRAFVLGDALGKDER
                     AQLAQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGVYAVRNDIAVVWPPNAAPIVMAIM
                     TNRGTADAPYDNKLIAEAASVVVRTLS"
     gene            complement(28214..28822)
                     /gene="vanX"
                     /locus_tag="C8250_RS01865"
                     /old_locus_tag="C8250_001870"
     CDS             complement(28214..28822)
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="vanX"
                     /gene_functions="resistance (resist) vanX"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029111.1"
                     /locus_tag="C8250_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001870"
                     /product="D-Ala-D-Ala dipeptidase VanX"
                     /protein_id="WP_138351788.1"
                     /transl_table=11
                     /translation="MKADFVFVDELASGIRWDAKYATWENFTGKPVDGYMANRVVGTRD
                     LCAALERAREKAQSLGFGLLLWDGYRPQRAVDCFLRWSKLPEDGRTKSRHYPNIGRAEM
                     FERGYVAAKSGHSRGSTVDLTLYDLSTGELAPMGGDHDLMDDISHHGAKEIGHVEARNR
                     QNLLSIMEASGFSAYDYEWWHYTLQDEPYPDTYFDFPIA"
     gene            complement(28819..29859)
                     /gene="vanA-Sc"
                     /locus_tag="C8250_RS01870"
                     /old_locus_tag="C8250_001875"
     CDS             complement(28819..29859)
                     /EC_number="6.1.2.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008716 - D-alanine-D-alanine ligase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="vanA-Sc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029110.1"
                     /locus_tag="C8250_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001875"
                     /product="D-alanine--(R)-lactate ligase VanA-Sc"
                     /protein_id="WP_138351789.1"
                     /sec_met_domain="Dala_Dala_lig_N (E-value: 8.4e-29,
                     bitscore: 99.2, seeds: 508, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.3e-05, bitscore:
                     24.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.1e-58,
                     bitscore: 197.1, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 6.2e-11, bitscore:
                     41.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARLKVGIIFGGRSEEHPISVKSAREVARHLDIEKYEPFYIGITK
                     SGAWKLGDGPDADWENGNCRPAVLSPDSSVHGLLVQEQGRYETIRLDVVLPVLHGTLGE
                     DGAMQGLLELSGIPYVGCDVQSSVLCMDKSLAYIVAGSAGIATPNFWTITADEKIDPGR
                     LTYPVFVKPARSGSSFGVTKVSREGELLSAVDVARQYDSKVLIEEAVVGSEIGCAILGN
                     DQDLVAGEVDQIALSHGFFRIHQEDQPETGSDNSAVIVPAAIPEESRLLVQETAKAVYR
                     ALGCRGLSRVDMFLKDDGEVVLNEVNTLPGLTSYSRYPRMMAAAGLPLSEVIDRTVSLA
                     LAGKRR"
     gene            complement(29852..30829)
                     /locus_tag="C8250_RS01875"
                     /old_locus_tag="C8250_001880"
     CDS             complement(29852..30829)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029109.1"
                     /locus_tag="C8250_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001880"
                     /product="D-isomer specific 2-hydroxyacid dehydrogenase
                     family protein"
                     /protein_id="WP_138351790.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 6.5e-53, bitscore:
                     177.6, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHSEPAHITIYGCGPDEAVLFRELAPRFGVTLTITDAPVSEANS
                     ELASGCRCISVGHKTQVTNATLLALGQAGVTYLSTRSIGCNHIDVEYADSIGISVENVS
                     YSADSVADYTLMLMLMALRDMKSIIRRSDLHDYRLSDVRGKELRDLTVGVIGTGRIGAA
                     VMDRLRGFGGRILAHDNRPTAVADYVPLDELLRRSDVVTLHAPLNADTHHLLNRQRMEL
                     MKHGALIVNTGRGALIDTEALVQALESGRLGGAALDVLEGEEGIFYADRRDRPMESKPL
                     LRLQELPNVVISPHTAYYTDHALSDTVENSLTNCLAFERRNQHG"
     gene            30996..>31148
                     /locus_tag="C8250_RS43230"
                     /pseudo=""
     CDS             30996..>31148
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837704.1"
                     /locus_tag="C8250_RS43230"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIPLSLGEIAEVVGGRVQGDSSVTVTAPAVLDGRQVEPGGLFVAF
                     TGEHVE"
     gene            31160..31282
                     /locus_tag="C8250_RS44410"
     CDS             31160..31282
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS44410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269287348.1"
                     /transl_table=11
                     /translation="MPADNDAAVHWLRGHVVAGDVVLIKASRGAHLDMVAAALA"
     gene            complement(31292..32401)
                     /locus_tag="C8250_RS01880"
                     /old_locus_tag="C8250_001885"
     CDS             complement(31292..32401)
                     /GO_function="GO:0016755 - aminoacyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0044038 - cell wall macromolecule
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384163.1"
                     /locus_tag="C8250_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001885"
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="WP_187144696.1"
                     /transl_table=11
                     /translation="MRPTVGPISAAEHLEFVRAQRSVSFLQTPAWGRVKTEWRSESLGW
                     FDGRRLVGAGLVLHRPVPRFERFTLAYLPEGPVIDWAGDIDAWLDPLAAYLKAHGAFAI
                     RLGPPVCTDSWSAAQIKEGIADPGVQRLTELRSQGDGQVGAHVTSRLRDAGWLPQSPED
                     GFGVGHPQFKYEVPLAGRTEGDVLRGMNQQWRRNIKKAAKEGVEVTVGEDLKAFHDLYI
                     HTAERDRFRPRPLRYFETMFAALSAEDPERIKLYLAHHQGDPVAAAILVRVGARAWYSY
                     GASSTGKREVRGSNACQWAMIRDALAAGCDVYDLRGVTPTLDADDPHVGLIQFKVGTGG
                     QAVRYVGEWDLPLRPMVYRAFDLYMRRGR"
     gene            complement(32398..33573)
                     /locus_tag="C8250_RS01885"
                     /old_locus_tag="C8250_001890"
     CDS             complement(32398..33573)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379301.1"
                     /locus_tag="C8250_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001890"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_138351792.1"
                     /transl_table=11
                     /translation="MSRTPPTAETAQDSPGDTRATGTGTGVPAAGTGGTWRAGVRRAIL
                     PRVLRWARAGDAPFGFRAGFWKRGLVLAALALLLGLLMLLHAKIPNRTVGLGSLVETFL
                     PWFGGFIPLLLAGALWRRSASAVVALLLPVTVWLTLFGGMLVDKSHDGSDLTVVSHNVG
                     ADNPDPAGTARDLAASGADLLALEEFTPQALNTYEKELAKPYPHHTVRGTVGLWSKLPL
                     SDTRPVDIETDYGPLGDTKPMEVKMAYNRALRTTVSTDHGPLAVYVAHLGSVRVNPRAG
                     FWTGSRDRGAQALGKAIAAERNERVVLLGDLNGTIDDRAFAGITSQLRSVQDAAGDGFG
                     FSWPANFPVARIDQILVRGVQPRSSWSLPATGSDHLPVAAGISWSTGRGRA"
     gene            33661..34356
                     /locus_tag="C8250_RS01890"
                     /old_locus_tag="C8250_001895"
     CDS             33661..34356
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018532776.1"
                     /locus_tag="C8250_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001895"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138351793.1"
                     /transl_table=11
                     /translation="MRVLIVEDEPYLAEAIRDGLRLEAIAADIAGDGDTAQELLGINTY
                     DIAVLDRDIPGPSGDEIAKRIVASGSGMPILMLTAADRLDDKASGFGLGADDYLTKPFE
                     LQELVLRLRALDRRRAHTRPPVREISGLRLDPFRREIYRDDRYVALTRKQFAVLEVLVA
                     AEGGVVSAEDLLERAWDENADPFTNAVRITVSALRKRLGEPWIITTVPGVGYRIDTQPG
                     AVHGGEDRG"
     gene            34367..35461
                     /locus_tag="C8250_RS01895"
                     /old_locus_tag="C8250_001900"
     CDS             34367..35461
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557580.1"
                     /locus_tag="C8250_RS01895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001900"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_138351794.1"
                     /transl_table=11
                     /translation="MSVRLKLTLSYAGFLMVAGALLLAAVWVFLLRYVPDRAMLINPDD
                     KPTHGVFPIRSGLLNVFAPRAAAVLAILLVFGLVGGWILAGHMLAPLTRITHATRMATN
                     GSLSHRIRLPGSKDEFRELADAFDAMLARLEEHNAEQQRFAANASHELRTPLAISKALL
                     DVARTDPNHDTGELVDRLHAVNTRAIDLTEALLLLSRAGQRSFTREPVDLSLMAEGATE
                     TLLPLAEKHGVTLETSGDVAPANGSPALLLQLTTNLVQNAIVHNLPEHGSVWVHTSVGP
                     NTVVLTVENTGEQLSPHLVSTFTEPFQRGTERIHTARTGVGLGLAIVKTITQAHDGTLT
                     LTPRSAGGIRITVELPATSPCTDG"
     gene            complement(35514..36131)
                     /locus_tag="C8250_RS01900"
                     /old_locus_tag="C8250_001905"
     CDS             complement(35514..36131)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS01900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_001905"
                     /product="hypothetical protein"
                     /protein_id="WP_138351795.1"
                     /transl_table=11
                     /translation="MLAYYLVASLGRSDAPTPPYVRWASLAVIACGLLLFLVGLLCGFD
                     VLYAGSLGTPLFLGGGLVVLMYGRLLLVKISGGRYPVLREKAALAIVAALIVLSSFWTV
                     NIYAQDHGKSDAAYLTDRLWLRPQVVLDTTERLYFQYPGVQETVLPEGTPQQHFRFRYR
                     GLRLLAQSGDRMFIIPQSWTVDRGNVLIIPLDANVRVSFRPG"
     gene            complement(36485..36841)
                     /locus_tag="C8250_RS01905"
                     /old_locus_tag="C8250_001910"
     CDS             complement(36485..36841)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS01905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_001910"
                     /product="hypothetical protein"
                     /protein_id="WP_138351796.1"
                     /transl_table=11
                     /translation="MNNTTGAAYEAQLEFHDCTPGQPAQSVSRHISVAPGASYFDEFHL
                     AATAPRITHTMCGTLVQDGGGPVTTFSDPIHPPSSAPPVPSDTPDSPDTPDSPDTPDTP
                     DVSEGPATSDASTP"
     misc_feature    36923..36938
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            complement(37574..37960)
                     /locus_tag="C8250_RS01910"
                     /old_locus_tag="C8250_001915"
     CDS             complement(37574..37960)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS01910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_001915"
                     /product="hypothetical protein"
                     /protein_id="WP_138351797.1"
                     /transl_table=11
                     /translation="MNDSARTPFLGCEAPAVPGGYLSWREPVTDHWWQQVWFDTAKPQF
                     RDLGKLTARAGSLRSAIDSRTKTALRIADSGPQSDRFTSAQTLTALVKKSTTSRADAWR
                     TQIQGLQSGQTLEGTWEGGAKDHG"
     gene            complement(37966..39597)
                     /locus_tag="C8250_RS01915"
                     /old_locus_tag="C8250_001920"
     CDS             complement(37966..39597)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019075895.1"
                     /locus_tag="C8250_RS01915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001920"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_138351798.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 5.9e-15, bitscore:
                     54.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPPANAPDTSPFALRGRLVTLDPHNTVVADGVLYIRDSVIEAVQ
                     PAGAPAPPGFEDIGPVVSGGTIYPGLIELHNHLPYDVLQLWPVPKKYSNRSQWGGSRNP
                     DYHRLVTGPMTVLGEDPRLMPAVVRYVEAKALVNGTTTSQGIALFSNAGARRMYRGIVR
                     NVEQTDDPALPEAGSRIADVEAVDAARFLARLRQPHRLLLHLAEGTDAAARAHFQALEF
                     QPGQWAITENLVGIHCTALTGEDFRILADHGGSMVWSPLSNLLLYGKTADIAAAKQAGV
                     LIGLGSDWAISGSKGLLGELKAARLASDAAGGVFSDRELVAMATRDAATILQWDQTLGS
                     LRPGMRADLLTISGAAGDPYGSLIDAGDEDIRLVTIDGVARYGTRRLMTALAPGAPLED
                     TATGAPADHVLNLQQDSADPIVAGVTLAEATSRLSHALHDLPALAARAAQPRVTARPDG
                     DLHWQLALDEIRPTGAELRPRLALRGNGGQPTGPQIATRLARQDGLVPLSLDGLTASSD
                     TAFLALLADEANLPDHFGAQLSDLLT"
     gene            39741..40553
                     /locus_tag="C8250_RS01920"
                     /old_locus_tag="C8250_001925"
     CDS             39741..40553
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015146.4"
                     /locus_tag="C8250_RS01920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_001925"
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="WP_138351799.1"
                     /transl_table=11
                     /translation="MHEFDPGYALEPYATLARSYPGPEVYPAEDFRIEWGPIFHRGRLD
                     GTARVLVLGQDPAAHEAIARRILVGTAGRRFQGFLGKLGIDTSYVMINTYLYSVYGQHA
                     GNAHATDPDIALHRHAWLDALTGHNPIQAVIALGSLADTAFHTWRKTPAGAAFTGAYQH
                     VLHPTYPDSAAASGADPVEAMTKLLTSWNTALDALHGTVTADTDRPLVRYGSILTAADL
                     ATIPEADLPPGLPAWMRSDEPWAARKGATSAEKRATITVRIPEDLRPF"
ORIGIN
        1 gccacgaggt cgccgacggc gagcgaaccc tcggccgcca tccgcgcggt cagccacgtg
       61 accagcgcga ggaacagtgc cggcagaccg atggccagcg cgccgatcca gctggtcacg
      121 gcgcccaccc ggtagccctg ttcgcgcagc tcccgggacc ggtgcccgta gcgggacgcg
      181 tagacgtcct tgccaccgag accgttcagg acccgcaacc ccgtcaccac gtcgacgagc
      241 agttcggtca gcgcaccctg ccgctgccgg tattcggatc cgacacccag cagccgccgc
      301 tgcaacggtc cgacggtgac ggcgagcagc ggcactcccg ccagcaccac cacggccagc
      361 agcggtgaga tcgacagcag cagggccgcg acgacgagat aggcgagaac ggcccccacc
      421 cccggcccca tcacggtcag ggacatggcg atcacctgca cgtctcccat cccgatggcg
      481 acgacctcac cggcaccggc ctgactccgc aagccggcgc cgagcgatgt ggcctgccgt
      541 acggtcgctc ggacggtgcg gaacgacgcg tccatgcgga ccttcgtcat cgtccggtgg
      601 cggaggatgc ccacgaccgc gttgaccact cccatgacga acaacgccgc ggtccagccg
      661 agcagcgcgg agctgtcctg tgcccgcagc ccgtcgtcga tcgcgcggga cagcaggtag
      721 ggcggaacgg ccagcccgac catccacagg ctgcccagca acgccccggt ggcgacccgc
      781 cgccgctggc tggtcaccag ccacagcagg aaccgcagag ggctccggat gtccttcgga
      841 gcaggcgggt gaaaggtgtc ggccatgccc gcaccctagc caccagcagg tcggcgcccg
      901 gcagccaggg ggacgttacc gccgcgacgg cacacgatct cccatcgccg gtgcatcccg
      961 gatgacgcag ccaccgatcc acactattga acacgttcaa attagctgta ggctgcggcc
     1021 atgagcgaac gaagcaccgc cctacggcag atacgcgcct ggctcgtcct gttcatcgtt
     1081 tgtctcgcgc tcagcggatt gacggccttt ccactggtcc acgaactgcg ctgggccgac
     1141 agcctgctgg ggtccaccgc tctcggggac tggttccccg ggctcacccg ctggatcacc
     1201 cgcgtccgca ccggactcga cacggccgac gccgactacc cgttcctgct gtacggaacc
     1261 gactggctgg ccttcgccca cctggtcatc gccgtggcgt tctacgggcc ctaccgcgac
     1321 cccgtacgga acatctgggt cgtcgagttc ggaatgatcg cctgcgccgg gatcatcccg
     1381 ctggccctga tctgcggacc cgtgcgcggc attcccctct ggtggtcggt catcgacatg
     1441 tcgttcggcg ccttcggagt catcccgctg tacgtcgtgc gcagaaagat ccaacgcctc
     1501 gcggcactgg acgacgcggc cggcccccgg cctgcggcgg tggcgcagcc cgcacagtag
     1561 aggccagcgc cctggcctga tctcccgccc caaggccagg gcttcgtgcc cgggggcaat
     1621 acctgcggcg atgacgccga ccgcgatggt cagccctggg gcggagtcac cggcaactgc
     1681 cttttgtgtt cggtcccttg gtacctgccc acgatcgaag cgaaggcacg ctcgctcacc
     1741 ggcttgccct ccaggaagtc gtcgatctcg tcgtacgtca ccccgagcgc gtcctcatcc
     1801 gccttgccct cgtcgagcgt ctccaggtcc gccgtcggca ccttccacac cagcgaggcg
     1861 ggcgccccga gcgcctcccc gacggcccgc acccggcgct tgatgagccc ggcaaggggc
     1921 agtacgtccg ccgcgccgtc cccgaacttg gtgaagaacc cggagaccgc ctcggccgcg
     1981 tgatcggtcc ccacgaccag cccttcatgc gcccccgcaa ccgcgtactg ggcgatcatc
     2041 cgctgccggg ccttgatgtt gccgtgcacg aagtcctggt gccgctcgtc gcggaaggcg
     2101 accccaccgg ccagacaggc ctccagcgcg gcatcgctcg ctgccttgac gttgacggtc
     2161 aggacctggt cggcccggat gaagtcgagg gcgagctgag cgtcctgctc atcggcctgg
     2221 acgccgtacg gcagccgcat ggcgtagaag gtcgcgtcgt gcccggcccg acgggcccgc
     2281 tccacggcca gctggcacaa ccgccccgcc gtggtggaat ccaccccgcc gctgatgccg
     2341 agcaccaagg accgcagtcc ggtggtcgtc agccgctcgg ccaggaacgc cacccggcgc
     2401 tcgatctcca cctccgcatc gaagatcgcg gcgacgtgaa gatcccgggc gatctcctgc
     2461 tgcaggccta tgggcgcggg aacggtcacg actactcctc ggggtcggtt cggggtgcag
     2521 attctatgct ggctgcctgc tgccacctcc cgcggactgc ggctggcagc aggtagcaag
     2581 gccgacggcc tcgtcgcggc gcggcccggc agcttcgccc cacgccgccg tagaccggca
     2641 acgagagctg gtggctgcgg tcctgacggt ccatacgctc gggccccgac gccgctgagc
     2701 ggcggacctg taagatcatt tactcagcgg tgccggacgc ctcacccgct ccgtcccgcg
     2761 ccgtgcacgt ctgagcgggt ggtaacacag agggatcaga acatgaagcg cgtcatacgc
     2821 ggcctcggag ccgctgccgt caccgccgtc ttcgccgggg gtctgctcgt cgccctgccg
     2881 ggcgcggcga gcgccaacga ctacgggtac acctgtaaga actggaagga caccagccac
     2941 agctggagcg ccgactgcca cgtgacgcgc ggcaaggccc gtacggtgac cgagtgcgcc
     3001 aacggcaaga cctactacgg caagtgggtc ggcagcgggt actggaagtt cgatggcgag
     3061 tgcggcaagt acgcactgat ggccaccgac atccagtgga agaagtagtt ccccgatgtc
     3121 ctgccccgtc gcagccctcc agggccgcgg cggggcgttc tcaccctctt ttccgcacgc
     3181 ccgggaagca gccaccggaa agcggcccaa gaggctgcga tcacgatcgg gatgcccgtc
     3241 aggaatccgt gcggcgcttg ccttcctcga agaacccctg gatcgcgtcg gcgttgccga
     3301 gttcccgcag cgcgcgtgcg gcgccgaaag gggcgttcca gaacttgcct tcgcgcggcc
     3361 ggtgcggccc gacgtaggcg tagggctccg gcaggtggtc gtcaccgggt gagaccccgt
     3421 agttcacctc gtcgagagtg atggcgaggt cgaagtgttc gggccagagc accggttcgg
     3481 tctcgggtgc gaaaccgcgc aacgcctcgt ccccggcggc gaacgcgcgg aggatctcgg
     3541 ctccggcttc cggatcgacc gtgatcacct cgtccggctt caccccggac ccgtccggat
     3601 agagcccctc cggagcgccg gcctcgatcc ccgccgcttc cgcgagcgcc gcgtaggtct
     3661 ggcccgacag cgcgatgcgg gccgttccgc tgacgaggtc gccgccctcg acacgcaacg
     3721 ccggttcgcc gatcgtgccg aaaccgccgc cgacgatccg cagccggatg cggccgatct
     3781 cccggtgctg cggcccggcc agtaccagct cggcgatgcc gtgcagggat cgcctggtca
     3841 gagccactgc gtcagcagtc atgccgcctc ctcgggttca tcgctacccg cgagtgtcgc
     3901 aggcggcccg ggtcgcggca ctgcgcgaca cccggcatgg ccgggctacg accgctgacg
     3961 gcatcggaat gactccgcta gcgggtggcg agccgctcca ggagggtggc gctccgtgcc
     4021 agcaacgtct gctcctcatc cgtgagttcg gcctcgatgg cctgcgcgag ccaaccgacc
     4081 ctgcggccgc gctccgcttc gagcgcggcc cggcccgcgt ccgacagctc gaccagcgac
     4141 ttgcggccgt ccgtggggtg cgcccggcgg gtgatcagat cctgctccat gagcagcccc
     4201 accgaacggg ccatcgactg gggacgtaca cgctgatcgg cggcgaggtc gctggtggtc
     4261 atggcgccgt cgcggtcgag tgcgccgagc acggcgacct gacccagcgg gatgcggtcc
     4321 tcgtgcttga cgcgtcgggt gagcttcccc atcgcggtgc gcagttctgc ggcgatggcg
     4381 gcggcttccg aggtgggcat agggcacttt accccgttgg gcagcattgc tgtgcacctg
     4441 acctgcacag caatgctgta cagcaaaact gggcagcatt gctgtatggt ttggcgttgt
     4501 cgggctcagc gccagcgctg tcgcagccgg ggccacggca cacgacaacg ggaaggacct
     4561 cccatgtccg cacaggcatc cgggaccgtc aacgccgcca tcgagaccgt caccgcccgc
     4621 cggatcatcg acagccgggg caaccccacg gtcgaggtcg acgtcgtcct ggcggacggg
     4681 tccctggggc gcgcggcggt cccctccggc gcctccaccg gtgcccggga ggccgtggaa
     4741 ctgcgcgacg gagaccccgc gcgctggcac ggcaagggcg tcgaccgcgc ggtggcccac
     4801 gtcaacgggg agatcgcggc gaccgtgcgc ggccgggacg cggcggacca ggcgggtctc
     4861 gacgccgcgc tggtcgccct cgacggcacc gccacgaagt cccggctcgg cgccaacgcg
     4921 atcctcggcg tctccctcgc cgccgccaag gccgccgcgg cggctcaccg ccggcccctg
     4981 taccgctacc tcggcggtgc cggcgctcac ctcctgccgc tgccgatgat gaacatcgtc
     5041 aacggcggcg cccacgccga caatccgctg gatttccagg agttcatgat cgcgcccgtg
     5101 ggcgcggaaa ccttcgccga agcggtccgc atgggcagcg agatcttcca caccctgcgc
     5161 cgtgatctgc tggccgccgg gcactccacg ggcgtcggcg acgagggtgg cttcgcaccc
     5221 gcgctgcgta ccgctgagga ggcgctcgac ttcgtgatga ccgccatcga gcgcaccggc
     5281 taccgccccg gcacggacat cggcctgatc atggacccgg cgtcgtcgga gttcttccgc
     5341 gacggggtgt acgactacgc gggcgaggga gtgcgccgaa ccccctccga gaacgccgac
     5401 tacctggcca agctcatcga cgcctacccg atcgtctccg tcgaggaccc gatggcggag
     5461 aacgacctgg acggctggcg ggagctgacc gcccgcgtcg gcgaccgctg ccagctcacc
     5521 ggtgacgacg tgttctgcac caacgagaca ctgctgcgcg agggcatccg caccggcgtg
     5581 ggcaactcgg tcctggtcaa ggtcaatcag atcgggaccc tgaccgaagc gctggccacg
     5641 gtggccacgg cccaccaggc gggctggacg gtcgtcatgt cgcaccgctc gggcgagacg
     5701 gaggacacca ccatcgcgga cctggcggtg gcgaccggct gcggtcagat caagaccggc
     5761 tcgctctccc gctccgaccg cacggcgaag tacaaccaac tgatccggat cgaagaggag
     5821 ttgggcgact cggcgcgctt cgcgggccgc tccgcactgc gtcgggcatg aacagcaggc
     5881 agcggtaggg accacgcggg cccccgagca ggatcggggg cccgctcgcg agaccggaca
     5941 gacacgtctt cctgactgct ggttcgccgc cgctcccatc cgctcggtga ggtgatcggc
     6001 ggggagcgct caggggccgg gcgtggaacc accggtgagc agcagcagcg cggtgacaag
     6061 gtcgtcggag gccgagccgg tggccagacg gcgcagttgg aggccgacga cgagtgcgac
     6121 gacggggccg gccaggcgtt cggggtccgg tacgccgagg ccgccgagga tggaggcggc
     6181 cagctggtcg taggcggtga agcattctgc ggccgccggg cgcagctggg ggtcacggcc
     6241 ggcgtggatg tagagctcga agggggcgat gtgctcgctg tcgaaggcgg tgtccgcgga
     6301 cacctggccg acgatggtgg cggcctgttc ggcggtgacg cagtcggtga tgtgacgtgc
     6361 ggcgaggtcg gtgaagcggc gggtctcctg gtcgacgaag gagcgcaggc tctcgcgcag
     6421 caggtcgtgc tgggtggcga agtggtacgt gatcgagccg agggagacgc ccgcctcctt
     6481 ggcgatgcgg cggttggtga ccgcggcgac gccgtcctga ccgatgatcc gcagcgtggc
     6541 ctcgacgatg cgttcacgcg tcggggtggg attcggcatg tgctcatcgt cccatggccg
     6601 gcccgttggt caggccatcc gccgcggtgt cgccgctgga gggaaggtgc ggggggttcg
     6661 gccgggcgcc gggaggagcg ggccagcgct cgtaccatcg ctggtcgtcc tcttgacagg
     6721 gaaatcaccg gcgcagccga aagcggtggg ctcgcccgcc acgtcggtgt cgtccttgac
     6781 ggcgatcggg acaccgagca ggggcagacg gtgcccggcg gcgaggcggc ggtcggccgc
     6841 gtcggcttcc gccagagcag cggtggcgcg tacccggcgg aacgcgttca cggtcggctg
     6901 ggtcgcctcg atgcgtgcga gagactcttc gacgaggacc cgggacgaga tgtgcccgcc
     6961 gtgcagggcc gcgctctgcg ccgccaggcc cgtgcgtgcg gaatcggcca tcgttgggcc
     7021 ccttcatcct ctcctactgt tcgttcgaac gaacagtagg agaggatggc ccccatggac
     7081 atcaacggat cgactgttct cctcaccggc gccggcggcg gcatcggcca tgccctggcg
     7141 aaggctctgg ccgccaaggg cgcccatctg gtgatcaccg gccggcgcgc cgaatcgctc
     7201 aagggcctcg aagcgtccct gggcgcacgg gtgctggtcg cggatctcag cgaccgcgac
     7261 gcggtcgtgc ggctggccga ggaggcaggt cccgtggaca tcctggtcgc caacgccgcg
     7321 ctgcccgcca gtggcgccct gctcgacttc accccagcgg agatcgaccg gtccttggag
     7381 gtgaacctgc gcgcacccct gatgctctcc cggctgctgg cgccgcacat ggtggcagcc
     7441 ggccgcggtc acctcctgat gatcggctcg atctcgggac ggacctcgtc ccccgccacc
     7501 tcgctctaca gcgccgcgaa gttcggactg cgcggattcg cccatgccct gcggcaggac
     7561 ctgcacgcca cgggcgtcgg cgtgtccatc gtgcagccgg gattcgtccg cggcgcgggg
     7621 atgttcgccg acaccggtgc cacaccgccc gccggggttc gtaccgtcac gcccgaacgc
     7681 gtggcggcgg gtgctgtcag tgcgctcgaa cgtgacaggg ccgaggtgaa cgtcgcgccg
     7741 gtcgaactgc ggctgggcag cgccatcggc agcctcttcc cctcactcgg cgccgccgtc
     7801 cagcgcaggg cggcgctcga gtccttcatc gggcagatca cccaggccca gcgccacaaa
     7861 cgctgagacg cgccgcccac acgaaagttc accgcggccg atgagttcgg tggggcggtg
     7921 ccgtctacct ccgtgaaagc acaacgggtg cttcccgcaa aggagatcac gatgtcccag
     7981 gcagccctgc ccaccacgac cgccaccgcc gccactgaca cgtcccgcac cgccgccgct
     8041 ccgggccgca aggcccgcat cgcgcttcgt acgctgcagg tcgtgctcgc gttgttcttc
     8101 atcgtcgcga gcgggctgcc caagctgttc gcggcgagcg ccgccgcgga gagcttcgac
     8161 aaaatcggct tcggcgactg gtacatgtac ttcgtcggca gccttgaggt ggccggcggg
     8221 atcgccctgc tgatcccggt tctgtccggc attgccgcga ccgccttcat cggcctgatg
     8281 atcggtgcgt tcatcaccaa cgtgacggcg ctggacggcc actacgcggc cacaccactg
     8341 atcctgatca tccccttcgc cctcatcgcc tgggcccgcc gccaccacaa cgcggaactg
     8401 ctccagttgg tccgccaccg ggcgtgaaca ccccggcacg caaccgctcc agcagccggc
     8461 gcccgccggg gccacgcccc cggcgggcgt ccggccatgc ccggattccc aggatgccgc
     8521 agggagaact cagcccggcg gtgcggacct cagcgccgcc agcagcgtac gggcgtcccg
     8581 gaccgtggga tggccgtcgc cgagacgtac ggcggcctcg tccacgacgc gttcggcgta
     8641 cgcagtcccg tccgtcccgt ccgtcccgtc gtagccgagc atggcgtggg agaccttgag
     8701 gcgcagggcc agggggtgat cctcgcccag ccgggagcgc gcctccgcgg cgaaggcgcc
     8761 gcattcccgg cgtacttgcc cggtcggctt cgagccgcct tcgcgttccc aggcgaggac
     8821 ctgggcttcg aggtcctgag ccgcggtgtc gggagtgcgg tcctcgcgcg gcgtgtcact
     8881 ggtgtcgccg cccatcgtcg gccgtgccgc gaccgtggtg tcgtccggcc tcgcgacccg
     8941 ggtgtggacg agcgtctcga agtggcgggt ggccgggagg gtcgcgtgct cccggatgat
     9001 ggtggtcgcc tcggcgggca ggggcggcgg ggcgaaccgt tccacctccg gtccgagagg
     9061 tgcccccgcc gagcctgccg cgagggccgc agcgaccgcg gcgggggtcg gccgccgggc
     9121 cggatcggtc tggaggcacg accgcaccac ttcctccagt tcggccggca gacccgccag
     9181 gtcgggcgtg ccgtcgcaga tgttggtcat cacggcgagg accttcctgc cccagggaag
     9241 gcgccccagg gcgaggcggg cgaggagcgt gccgagggag aacacgtcgc tggccggggt
     9301 gaactgctcg tgctcccgta tctgttccgg cgaggcgtag gcgtacgtcc cggcgaagcc
     9361 gctccggggc tcggtcagcc gctcgatctg cgcgatgccg aagtcgatga cgcgggggcc
     9421 gtcctcggtc agcagcacgt tcgcgggctt gaggtcgaga tgcacgatgc cctcggcgtg
     9481 gatggcagtg agcgcggtgg caatgcccgc accgataccc cggacggtgg cggcatccag
     9541 ggcgccgcac cgctcggcca cctcctgcag cgaaggtgcg gccacgaacg gcaccgccat
     9601 ccagggggtc ccgccgctcg tgtcggctgc gatcaccggc acggtgaacc ggccactgac
     9661 tcgacgggcc gcttgcacct cgtgcgtgaa cccctcccgg atcgaggagt cggccgcgta
     9721 ctccgcgtgc agggtcttga ccgccaccat gacgccgtcg ggatcctggc agaggtagac
     9781 gcggccgaac ccgccctccc cgacgcgctc caggacctcg taggaaccga aggccgccgg
     9841 atcctccgct gtccgcgcgg acgtggcccg ccccacctgc cgccactccc ccagtgcctc
     9901 ggcttcggca tggacggccg tggcaccgcc cgggccgcgg gccggcgcgg gttccggcgc
     9961 cgcctgctcc tcgtccacca cgacgatcga caccacttgg ggtgtgcccc cacggaagga
    10021 gtacgcctcc acgttcacat tgccggcacc ctcgttggag acgtagacgc cgagcagccc
    10081 cagccgcgcg cacagggcga tctcctcggg agtcggtcga cggtccgcgc gggcgaagta
    10141 gaaggatcgg gcctcgcacc cctggtcggc caggcgctgg atcacgccga gccactgctc
    10201 gatgctcacc ttgtgcggtt gcggatcatc ggttccgtcg ctgaccggga agacccgagt
    10261 gaggtgccgg gcgcggttct cccgggccag cagcccgaag gccgtggcgg gtgccgcttc
    10321 cacctgcctg gccagcaggg ttcccgccgt gtcaccgatg tggagcgttg tctcccgggt
    10381 ggaccgggcg agtccgtccc gttgctcgga cagcacgtcg tactcgggtg agcccgggcc
    10441 ctctcctcgc agctccatgc acgcgagcac gcgcccgaaa cagacgacgg cttcgtccag
    10501 gtcctccgtc cgcatggccg ccttcgcctg cgagaccaga gctccgagtc tccggtcgct
    10561 gcccgcgccg tacaactgcg cgcatttatc ggcgatttgg ccgtacatgc ggctcgcccg
    10621 cgaaaggtcg ccgctccgct cgacctccgc ggccgccgcg accaggtcct gcagactgtc
    10681 gtgccctcgc tcgtggccga agggcagccc gccggcgagt tccgcatagc gctggcgggc
    10741 gataccggtg agtgcgtgcc gaccgccgag ctcgttctcg gcagtcttca gcatccgggt
    10801 gtaggtgcgc agcgcggcgg cgttgtcgcc ggcctgctgc tgccagtggc ccatgtcgca
    10861 gagcaggttg agcgcggcct cggtacggcc ctcctgctcg gccgaacgtt gcaactcctc
    10921 gtaacggcgt acggcttcgt cggctcgccc tgcccggccg tgccagtggg cgagctggtg
    10981 gcgggccagt ccggtgtcct gatgcctgga tccctgcagc cgctcgcggt cggagaggag
    11041 ctgcgcgaac agccgcaccg cgccctccgc gtcgcccgac tcacctgtcc agtgggcgag
    11101 ttggtgccgc atggccagag tggcggggtc gtcgggcccg ggcgcggccg tcgcacgaac
    11161 gaccagttcg cgataccgct tcaccgcctt gcccggcctg ccctcccggc cgtcctgctc
    11221 ggccgaggca ctgccctccc gcagccgcgc gagcacctcg gccgccggat caccggactc
    11281 cggtgtgccg ttccgccgct tgccgatcca ccgcatacag accccccgga gctgtcggtc
    11341 ggccgacatc ccggcctgcc ggcaggccgg atgaagagcc ggtacacggc aaagtaccgt
    11401 tcctcaagag tgagcggggg tgggtcgccg atccgttcct gttcactgcg cctgcctcga
    11461 caggtgttgg gcgggccggc ttgccgcgtt cgcgcgtccg agccgcaggt ctcggtggag
    11521 gagccatgcc gtaccggcga cgaccacccc gcagaccgtg ggcacgagca gccacggcag
    11581 gcccgtccac acggtgccca gacccacgac gacgcaggtc gccccggtga cgatgagcag
    11641 ccacttgccg tacgggcgcc aggtgaacag tccgggatca cgcgggcgga ccagatgcat
    11701 cgcaccgaac atgaatgcca acgccgccag cagccccgcg aacgtgccga cggcggctgt
    11761 catctgcggc tcgtcgcgag gcgcgtcggc ggaatgctgc cgggcgtccc cctcggcgac
    11821 catgaccacc acgccgcgcc agacagttgc cgtgacccgg tcccccttct gaagcccact
    11881 cagcgtcggc cccgagtcac tgaacgacac caccaccctc ccgaagggcc gtgggccgag
    11941 gagggtcgcc cgcatgttct tggcggtctt gtgggtgccc tcgacggtga agctcagctc
    12001 ccgcagacag tcctccgacg ccggtatcac cgtgcgcacg gaacacacct cggccgcccg
    12061 gtactcccga tacagggcac cgtcggtggg cagccagctg gtgaagacga aagcgcaggt
    12121 cagtgccgat accagggaca acacgatcag cgccgcaccc accagccggt tccggccggc
    12181 cccccgtcgg gacgacggcg atccgcccgc cgcccgctca gcgccgatcc tcatcgtggt
    12241 catcgctcga ctcccccacc gttgcccgcc gaaatccgct ggacctcact ctcttcccgc
    12301 cgtgatcaag gaggtaagga cagcgaccgg caatgagacg tcacccgtcg ttgctgaatc
    12361 cgggcaacgt gaacctcagc cacgccaggg cgcccgacac gacaccccca ggacccaccg
    12421 cgtcggtcgg cccggacggc acccgcgccg cctcgccccc cactcgcaga atcacctggc
    12481 tgaccagcgg cgatccggac acgcatgacc caccggggtg aaaggcacag ccaggagcag
    12541 tcttcgctct tccgcgagcg agcggcggcg gacgtgggaa gatggcagag cggaaaaatg
    12601 acctccgggc ggtctcctga ccatgcaatc gagaggcaaa tggacgggcc gacgactggt
    12661 gcggacgtgg gacgcgacgc ggcgggcggc gaggcgctgt cacgcggcct gctgttcatt
    12721 cccatcgcca cagcgctgat ccaggacgac ggacgcatca ttcactggag cgccgacgcc
    12781 gaggtgctgc tcggctacac agccgaggag gccgtcggcg ccttcgcctc ccacctgctc
    12841 gtggacgtgg aacagcagcc gcgcgtcatg gacctcttcg ccggcattct gggcggcgag
    12901 gcgtggtccg gggtcttccc cgtgaagcac cgtgacggcc actcggtgaa cctggagttc
    12961 cgtacccatc ccatcccgac cgagtccggc cgtcccctcg tcctcgccgt ggcatcggac
    13021 gtcagggaga tccgccgcat cgagtccgac ctggccgtcc tcgacagttt cttcacgcag
    13081 tcacccgtcg gcatggccgt ctacgacacc gacctgcgct tcgtacggct caacgacgcc
    13141 ctcgcccgga tcaacggcct gcccgcggat cagcatctgg gccggcgcct gaccgaggtg
    13201 ctgccggggc tcaacgggga ggagatcgag gcggtgatgc ggcaggtgct ggagaccggc
    13261 gaaccggtcg tggacgcccg gtcccacggc atcacgcccg cggacccctc gaaggaacgt
    13321 gcctggtcgg cctcctactt ccggctggag gaacggaccg gtcggatcct cggggtgagc
    13381 tccacgatca tcgaggtcac cgagcgcttc caggccgagt cgcgggccgc cacagcgcgt
    13441 gaacggctcg aagtgctcgt cgacgccacg tctcggatcg gcaccacact cgatctggga
    13501 cggaccgcgc aggaactcgc cgacaccatg gtcccccggc tggccgatgt gagcggcgtc
    13561 ttcgtcctcg agcgcctgat caccgggcag aacgcggatt cctcggcacc cgacggggcg
    13621 gagcaggtcc gccgcctcgc gatcgccagc tccgaccccg gctatccggt acgggacctg
    13681 ccggtcgacg cggtccaccg ggtgccgcgg gattcgccgt acgccgaggc gatggcgacg
    13741 caccggacgg tcatcgtgcc ctcggtggat ctccccccgc tcgccccggt tgaggccgcc
    13801 gaacgggtcc acgcctacca gacccgggtg tcccggacgg tgcgggtgac tccgctggtc
    13861 gtgcgcgggg ccgtactggg catggtcgtg tactcgcggc gcggcggcat ggaggcgttc
    13921 ggcgaggacg atgtcacgct gggtgacgag ctgacctccc gggccgcggt ggccgtcgac
    13981 aacgccctgc tctaccggcg ggagcacgag accggggagt cccggcaaca ggcgctgcgc
    14041 caggccaacg cggcccgtga gcggctcgcg ctgatcaatg cggcgtccgc ccgcatcggc
    14101 accacgctgg acctgacgca gacagcgcgc gaactggccg aggtcgccac tccgacgctc
    14161 gccgacacgg tcgtggtcga ggtcgtggac gctctgctgc gcggcgagga ggtccccggc
    14221 ccgcccgacc ggtcggcgct cctgcgccgc ctggccttcc acaccaccga cggtgcgggg
    14281 atggtgccgg tggccccggt cggcgacgtc caccggttcc atcccaccac gccgtacgcc
    14341 tggagcctgg cgcaccgtcg gcccgtgctg gtaccccgga tggacgaaga ggggctgagc
    14401 tggttcgccg aggatccgat caggaacgcc gcgtcgcgcg agcagggtct ccgcagtttc
    14461 atggtggttc cgctgatcgc acgcgacgcg gtggtcggag tggtctcgtt ctaccggacc
    14521 atcaccgacc ggccctacga cgaggaagat ctggcactcg ccggagagct ggcggcccgt
    14581 gccgcggttt cgatcgacaa cgccctgctc tacacccgtg agcgggacgc gtccaaggcc
    14641 cgccagcagg cgctggagga ggcccacgcc gcgcaggagc ggctggcact gctcaacgac
    14701 gccagctccc ggatcgggac cacactcgac ctgcagcgga ccgcggaaga actggtggag
    14761 ctggtgatcc cgcggttcgc ggacttcgcc acggtcgacc tgctggaatc ggtcgtccag
    14821 ggcggggacg aggagggcga ccagacgacg tcaccgaccg acggaagggt tctgctgcgt
    14881 gctgtcgcgg tcggcgaggt caacgagtcg ggcatgatcg gggcggccga cgaggtcggc
    14941 gggacctccc ggtcggccaa gctctacgcc gagagcctgc gcaccggccg gtccatcctg
    15001 gtggcgcagg tggacgaggc cgccctgcgc cggatcgtgg cgcaccccga ccgcgtccag
    15061 ccgggcctcg acgcgggcgt ccactcgtat ctgatggtgc cgctgcccgc ccgcggtgtg
    15121 gtgctcggcg gggccgagtt catccggatg cgcaatccgg agcccttcac ggtggccgat
    15181 gtcgcgctcg ccgaagagct ggcggcccgc gccgcggtct gcatcgacaa cgcgcgcctc
    15241 taccggcgtg aacgcgacac cgtgctcacc ctccagcgca gcctgctgcc gcaggaggtc
    15301 cacctcacac cgggcctgga gatcgcctac cgctacctgc cgagcagcgt cgtcagcgag
    15361 gtcggcggcg actggttcga cgtcgtgccg ctgtcgtgtg gacgggtcgc cctgatcgtc
    15421 ggcgacgtga tgggccacgg catccgcgcc gccgccacca tgggccagct gcgcaccgcg
    15481 gcccgcacgc tgatcacctt ggacatgtcc ccggaccggg tgctccggcg cctggacgag
    15541 acggcgtcgg cgatcgggga cgggcagttc acgacctgtg tgtgcgcggt gttcgatccc
    15601 gtcgaccgca gctgcatcat cgcctgcgcc ggacatccgc cacccgtggt gcaggacccg
    15661 aacgggtcca cgcggctgat cgacctgccc cccggcgtcc cgctcggtgt cggcggcgtt
    15721 gccttcgaga acgtggagat caccctcccc gaggacggtg ttctggtgct ctacaccgac
    15781 ggactgatcg aacggcgcga ccgggacctc gacgagggga tgctgctgct ctcgcaggcc
    15841 gtggccaacc gcggaccgtc cctggaggcc agctgcgacg ccgtgctcga cgcgctgtcg
    15901 gccaaggaca gcgaggatga catcgccatc atcatggcgc gggcaatgcc ggtacgtgac
    15961 gactggatcg ccatgctgcc gctgtccggc gacatggccg tggtgggcga ggcccggagg
    16021 ttcacccggg cgaggctgtg ctcctggggg ctgcagtcgc tcagcgaggt cgccgaactg
    16081 ctggtcagtg agctcgtcag caacgccctg ctgcacaccg gaatgcccac cgagctacgg
    16141 ctcttccgcg accgggtcct cacgctcgaa gtggccgaca ccgacaacca ggtaccccgg
    16201 gtgcgccgcg tctccgagga ggacgagggc ggccgcggta tgcacctggt caatgaactc
    16261 gcccaccgct ggggcagccg cgccacccgc cacggcaagg tggtctggat cgagttggaa
    16321 ctgcccctcg gcaccttcac cccaggcgga ccctgacctc ggccgccgcg gaacgctgtg
    16381 gtgaaaggct gcggaccccg agatcgacga cctgttggcg agcgtggccg acaagatctg
    16441 gaagaacaag cgtgtccccg gcccggaaga tatcgtgatc acgcggccgg ctgcggcgag
    16501 cggcagtgac ttgagcgcga cgacgaggaa catcgcgcag tgaagtccgt atcggattcg
    16561 aggcattggg ggtgccgcgg tggtgtcgaa acgtgtcaac gtcgtgggag cggggatcgt
    16621 cggtctgagc atcgcccacg atctggccct gcgcggccat gccgtcacgg tgatcgctga
    16681 tcagcgggcg gaggagagcg tgtccagcgt cgcggcggcc gtgtggtttc cctaccggag
    16741 cgggacatcg ccgtcgctga tgggctggtt gctcgcggcc cgcgcgcggt tcgagcagct
    16801 ttccaccgac cgtgccgccg gtgtcgatct ccgggaaggc ctcgtggtcg agcgacacgt
    16861 cggggaggac cgctcatgga ccgatgcggt ccccctccac cacgaggccg ccgcggacga
    16921 gctgccctcc ggcgcggtgg cgggggtgcg ggcgaccgtg cccgtcatat ccatgccgca
    16981 ctaccttccg tggctggaga agcgctgcac gggcctcggg gtgacgttcg tcgagcgcaa
    17041 ggtcacggcc gtcgacgacc tcgccggcga tgccgacctg gtggtcgtcg ccgccgggat
    17101 gggttccgga gccctcctcg acgacgattc gatgtatccc gtccaagggc agatcgtccg
    17161 cctggccaac ccgggaatca ccgagtggat cactgacacc gagaaccccg ggggcctgac
    17221 ctacatcgtt ccccgccgtg aagacatcgt ctgcggcggc gtggcgcagg tcggctcatg
    17281 ggccacggaa cccgtggccg agatcgagca ggcgatcctt cgccgggtgg tctccctcat
    17341 gcccgcgctg gccgggctgc ccgttctctc gcgcgccacg gggctccgcc cggcccgcga
    17401 caccattcgc ctggaacacg tcgacggttt tcccgtcccc gtgatcgcct gttacggcca
    17461 tggcggtgcg ggtgtcactc tgtcgtgggg ctgcgccgag gccgtggcag acctcgccga
    17521 ccagatctga cgtcaccctg ctcgtgcacc cgcgctctgc cgccggggcg gcagagcgcg
    17581 gccgtcgtcg accgccgggc gggtgaccgc cagcccacgg cggacgtgtg cggatacgct
    17641 ctgtgaccgt ccgctctcat cgcgcgatct gcccttgcag gcgaagaggg cgcgagtgtt
    17701 attcaatggg tgtgcgtagg ggatctcggg gcttcaccgc acgagagact cgggtacgcc
    17761 tccggtcatg tgccggggtc ggcgagcgag ctgagagagc cgcatggact ccacatcatc
    17821 ccccttgccc tcgtcgccgt tcgagcaggt cagccgtgcc ctgggggact acattccgcg
    17881 ggacggaccg gcagccgcag ccgatcccgc cgccccgcag ggcgaccact ccgatcctcg
    17941 gtcaccgaac ggcgaccgcg cgaccaccgg ccaggagcag atcctcggcg ccgtcaatct
    18001 ggaccgggaa ctgagaatca ctcgctgcaa cctggacgcc cccgccttcg atgggctggg
    18061 ggtcaccgtc ggagcggcgt tcgccgatct gctgcctccc ggcgacatcc cgacggtcat
    18121 ccggcggttg cggcaggtca tcgagacagg ggaggcgcac gtcgcccggg tccagcgtct
    18181 gcggcgggac gacgggtcgg agctggtggt atccatgagc atcctgcccg ccgcggcgcc
    18241 ccaggagggc ctgaccgtct ccctgatcgc catggccaag aggttgcatc tgtacgcttc
    18301 cgagaccgcc atcgggacgt cgctggacat cggtgagacg gcgcagtccc tggcccagtc
    18361 gttgctggtc tggggagacg tggccgccgt cgacctcgat tacgccgtgt ggacgggcga
    18421 ggccgtcacc gagcaggctc aggggcgcat ccggctgcgg cgggctgctc ttatgccgga
    18481 cagggcctgg cccgagggct atctgacgcc cggcgacaac cttcccaacg aggcgagccg
    18541 tctgctgtcc ctcgcggtca cgcgtgacga cgtcgcgcag gccctcgtca ttcccgatcg
    18601 ggaggcgatc gagcgggtgc tcggcgatcc gcgactggtg cgtgctctgg tccccgtcga
    18661 ccggccggcg agtgtggcct gcataccgct ggtcctggaa ggctccgatg gcgcaccgcc
    18721 catcgtgctg ggcgtggcgg aggtctggcg gcggccggac cgccccttcc acgacagcga
    18781 gttgctggat ctgcaggagc tggtggccag gaccgcccac catgtcgatc tggcccgcca
    18841 gcaccagcgc gagcacgctc aggtactggc gctgcagcgc cggctgctgc cgcgcgccgg
    18901 cagcgacacc atcgaggtcg ccagcgtcta ccagcccacc acccccgaca gcgcgggcgt
    18961 cggcggtgac tgggtgaaca gctttcccct gccggacggc cgtaccgcac tcgtggtcgg
    19021 cgatgtcgtc gggcacggtc tgggggccgc ggcagccatg ggccagttga gcatggaggc
    19081 ccgggcgctg ctgtcggcgg ggctggcgcc cgatgaggtg ctggcgcatc tggacgagac
    19141 cgtcacgctc ctggacgacg cggacgccgg cctggcggcc ggctacagcg cgctcgggtc
    19201 gacctgctgc atcgcggtct acgatccggt cggccatcag gtggtcacgt ccagcgcggg
    19261 ccatctcccg ccgatcctcg tcctccccga cgggtccgcc aggactctcg cgacgcaccc
    19321 ccatcctggc ctgggtaccg ccttcgcctt gcgggagccg ttcgatgtgc acaccttcgc
    19381 cgctcccccc gggtccttgc tcgcgctcta caccgacggt ctggtggagg atccggcggt
    19441 ctcgatcgac gagggcatcg accggctgac ggacgcggtg agcaaggtgc atccctggga
    19501 cgacctgcag caggtcgcga ggagcctggt cgtcgagttc gcctcgcgaa gccgcctgcg
    19561 cgacgacgtg accttgttgc tcgcccgcat ggccgggcgt cgtaaacggg acaccgcggc
    19621 ctggcgtctg ccggcgcgcg acgacgccgc cgcccgggcc cgcacgctgg cctctgccgt
    19681 cctacggcaa tggcacgcca agagcgcccc gcgcgacagc gcgctgctgg tgatcagcga
    19741 gctggtcacc aacgccgtcc gcttcgccac cggtcccatc acggtgcggc tgatcaagac
    19801 cggtcacagc ctgctgtgtg aggtcggtga caccagcaac ggccggccgc ggctgggccg
    19861 cggtggcctg ctcgacgaca gcgggcgcgg cctgcgcgtc gtccacaagc tcaccacccg
    19921 ctggggggtg cggtggaccg acaccggcaa ggtcgtctgg gcggaactcg cgaggtagca
    19981 ccaccggggg gtcagtacac ctagagccac tccgcctcga cggccgtggc cgtgagtccg
    20041 ggcgccgccg cgaagagcac ggtacggctt cccgcgctct ggccggcgtc gtgcgcgcgt
    20101 cgcaggatgt cgaacacggc cgcaccgccg cggttgccgc tggtgtagct gtcgcggctg
    20161 taggccagga cgtcggtcgg ccacccgtcg ggcatcgtct gttccatgta ctccagcacg
    20221 cgggtcccgc cggggtgcgc gagcaggaga tcgggatgcc aggggttggc gtcgtcctgg
    20281 tgacggaggc gcagccactc ccacatcgcg acgaccgtgt cctgtacggc gcgcggcccg
    20341 cgccggtcca tgacgaagtg cgtgccgtcg gcacgggtgt ccagccggtg caggtcccgg
    20401 gtgccgggca gggtgtggtg ccaggccgcg tccagccgca gcaccgactg cggcctgggg
    20461 cggccggtga ccaccgcggc gacggcggtg tccgcgaaca gcagccggac gatcaaggac
    20521 tccagggtgt cgtccgcggg ctggtaggtg gtgctcagcg cctccgatat cacgaccaga
    20581 accacccggt cggggtccgc ggccaccagg tcggccgcca gcgcgaggga gcgggtcccc
    20641 gcgatgcacg cccactgcgt ggccgggagg agaagcgcgt catcgcgtag cgacagccgg
    20701 tcggccaccg ctatgtccag tcccggcaga gccggggtgg tcgagtggct ggtgatcagg
    20761 cagtcgacgt cggcggcgtc cagccctgcg atctgcagtg ccccgcgcgc tgcccgctcc
    20821 ccgtacgcct gcacggcttc ccaggcgggc gcggtgcgct cctgcacggt ctgcggcgcc
    20881 ggtatcgcct cgagcgcgct gatcgcgcgg tccacttcct gctcgctgaa tccgtcgcgg
    20941 atcagtgcct gccgggccgg tgcgacgccc ggggtccgca ggccgctccc ggcgctggac
    21001 gcgacggcgg tggccaacgg caccatccac ccgcgggaag cgatgccggt actggccgcg
    21061 atgccgtcga tccgcggcag ccacggcgcg tgctgatgcc ggtcacgtac ttccgccagg
    21121 atctggctgg tctccacggc atgctcgccg tgtatcaccg cgggagggca cagataagcg
    21181 gtcacagtac gcacctttct acgcaggatg atcgaatgcc acggagcata tgaaatgagt
    21241 cacttcatca cttcatgtcc aagtgagtac ttttgcactc cacttcagga gttatctacc
    21301 tttttcgggc agatcggcct gtgagaaacg tctctgtggt ccacgccact ccgagaactc
    21361 caagatcgcc cgagtgcaca ggccgacgac gccgtctctc gccggccacc tcggcagggg
    21421 caggttcacg gacgtcggcg gcgtcccggt gggcccattc ggcagccgca gcagccttgt
    21481 tgccgcagga gagcgacgat cccgccgcgc cgcactgcga tgcgccgcct gacatccgta
    21541 tacccctcaa ggggtgacga agcgtcagca ctccccggcc gtgcgggcgg acgcatgaag
    21601 tccttgccct cgggtccgga ccgctgccac ggagtggtgc cgcgcttcaa gaaccggagt
    21661 tccgtttcat ccgtcgacac caatcgtgca gctcgaaggg ggcctactct ccggatccga
    21721 ccctcatccc cttgcccgga aaggccgctg atgttcgagg agctgcaccg tcgcgctgtc
    21781 gtcgccgacg cccacaacga tctgttgacg gcagtcgccg cccggccccc gaagcgctgg
    21841 ggatccttct tcagggagcg ctggctgccg cagctgcaag cgggaggaat cgacctgcag
    21901 gtactgcccg tgttcatcga cgcgccgtac caacctgagg gtgcgctgcg gcagacgctg
    21961 cggatgatcg agtgtgtcca cgtccgggcc gaggagaacg ccgatcaggt cgcgctgtgc
    22021 ctcaccggcg cggacatcga cgccgccctt gtccaggaca agctcgctct ggtgctcgcg
    22081 ctcgagagcg cccccggcgt cggcgcctcc accgagctct tttcgacctt gcaccgcctc
    22141 ggcgtgcgca tcgcctccat cgcccactgg ggccgcaccc cgctcgccga cggcagccgc
    22201 gaggacgcca cgggcagccg cctcaccgct cccgggtcgc cacgccggat ctcgaccgac
    22261 aggtcccgga gcgtcaaact cttgcgcaca tccattcgcc gatattgagg gccgcggcgc
    22321 gtgcgctgtt cgtccgggac ggcgagtgtt cagccccgcg ttcgtccgga cgaacgaacg
    22381 tcggcgcgac ccgtgtgcag gtagcgtgcc cgcccctcgc cgtcgtcgcc caggaacgcc
    22441 accggtccat ggccgggctc gacggggagg agggaatcgc cgcgccaggc gaccaattcc
    22501 gtgcggtaac tctcgtcacc gagctccgcc gtgatgccga ggggcacatg ctcgagccag
    22561 agcctgccct gctcgtcctc acccaccctg gtctcgcccg tgctcgacag ataggtgccg
    22621 acgcagcgcc gcgcgttcag gcggactgcc gggtccggga ccgggtcccc gggcagctcc
    22681 aggatgcggc cgaggatctc cttccgcagc ggcttggggt caccgccgtt ggtgaagatc
    22741 gccactgcca ggtcgcggcc gggcacgacg cgcaggaccg ccgactggcc gatggtgttg
    22801 ccgtcatgac cgaagaccag gccgcccggt aggccgtaga gctcccagcc caggccccag
    22861 gccgtgcccc agccgatgtc cggcagcgcg acctgcggct gccgcatggc ctgtaggtcg
    22921 tcctccgcga ggtgcgtccg ggcgaaggcc agcagatcgc ggggagtcat cgcgagcatc
    22981 gaccccgccg gcgcgttcga gcgggccatc gcccagaccg cggacggctt cccgtcgaga
    23041 tggcccacca ccgcgcggtg gacgatcgct tcgtacgggt cgttcgccgc gtgcgtcatg
    23101 cccagcggcg tgaacaggtg atcacgcatg cacgcgtcga agggcttgcc ccgcacgacc
    23161 tcgacgatgc gtcccagcac gcagtagccc gcgttgttgc aggagaacat catgccgggc
    23221 tcgaagttct gcggcacctc gtccagcagg tccacgtacg tggccaggca gtcgtcgccc
    23281 ttgccggtgt cggtgaagac atccccttcg aaaccggagg tgtggcacag cagttgccgc
    23341 acggttgcct cccggaaccc gggaaggtag gtccgcaccg gagcgtcgag agctactctg
    23401 ccttcgccga ccagctgcat caccaacgtc gcggtgagca ctttggtgat cgacccgatc
    23461 tggaacaccg agtcgaccgt cgcctccacc cccgtcgcgg tactcagtac cccggcggcc
    23521 acttcgaccg tcttcgcgcc cgcgccgatg gccacggcag cccctggcac accgtgctcg
    23581 gccaacagct gcggcagccg ctcccgcagc caactcccga tgtcgtgcaa ttcgtccatt
    23641 cgcccaaagt agaccccggg aatcagcccc ggttcgtcca cggcgaccat cgttctcgcc
    23701 tggtttcgtg gaaacgacca ggcccggcac cctcagtgat catgccgtga ttgtgaagct
    23761 gagctgtgga cccgcataag aaaccatcga tggaccgatg ggcagggcgg acggcaaggt
    23821 ttggggtctc cgccgtgctc gcggcggatg cgcgtcgtac cgattccgag gggctccgcc
    23881 gtgaaggcac tggtcaaggc gaaggcagaa ccgggtctgt ggctgatgga cgtgccggag
    23941 cccgaagtcg gacccggcga agtgctcatc aaggtgctcc gcaccggtat ctgcggcacc
    24001 gacctgcaca tccgcgacta cgacggctgg gcgcagcagg ccgtgcggac cccgctggtg
    24061 ctgggccacg agttcgtcgg cgagatcgtg gaagtcgccg ccggcgtcgc cgacttggcc
    24121 ccgggcgacc tggtcagcgg tgaaggccac ctcatctgcg gaaagtgccg caactgcctg
    24181 gccggacggc ggcacctgtg tcgcagcacg gtgggcctgg gcatcgggcg cgacggggcg
    24241 ttcgccgagt acgtgacgct gccggcaacc aatgtgtggg tgcaccgggt accggtggac
    24301 ctggacgtcg cggcgatctt cgaccccttc ggcaacgccg ttcacaccgc gctgtcgttc
    24361 ccgctcgtgg gcgaggacgt actcatcacc ggggccgggc ccatcggcat catggccgca
    24421 gcggtcgccc ggcacgccgg agcccgacag gtgatgatca ccgacgtcag cccgttccgg
    24481 ctggagctgg ccgagaaggt cggcgtgagc ctggctctgg acgtcagcag ctccaccatc
    24541 gcggacgggc agcgcaggct cggtttgcgc gagggcttcg acgtcgggct ggagatgtcg
    24601 ggacggcccg aggcgctgcg cgacatgatc gccaacatga cccacggcgg acggatcgcc
    24661 atgctgggcc tgccggccga ggagttcccg gtcgacttcg cccggatcgt cacctcgatg
    24721 atcaccctca agggcatcta cggccgggag atgttcgaga cctggtacgc catgtcggtg
    24781 ctgctggaag gcgggctcga cctgagcccg gtgatcaccg gccgctactc gtacaaggac
    24841 ttcgacgccg ctttcgacga cgccgccggg ggccgctgcg gcaaggtcat cctcgactgg
    24901 accgcctagc tcccgctcca gcggcctccg ccggaaccag cccgcgcacc atcagacctc
    24961 cgcaggaaca aggagagacc ccatcatgct cgacgccgtc cgcgaggacc tccgtgccac
    25021 cctcgatgag atccgctcgg ccgggctgca caagcccgag cgggtcatcg gcaccccgca
    25081 gagcgcctcg gtcgacgtca ccgcgggcgg acgccccggg gaggtgctga acttctgcgc
    25141 caacaactac ctgggcctcg ccgacaaccc cgaggtcgtg gccgccgcca agtcggcact
    25201 cgaccgctgg ggctacggca tggcctcggt gcgcttcatc tgcggaacgc aggaggtgca
    25261 caaggagctg gaggcccgcc tgtcgcgctt cctcggcatg gaggacacca tcctctacag
    25321 ctcctgcttc gacgccaacg gaggcgtgtt cgaaacgctg ctggacgaac gcgacgcggt
    25381 gatctcggac gcgctgaacc acgccagcat catcgacggc atccggctgt ccaaggcacg
    25441 ccgcttccgc tacgccaacc gcgacatggc tgacctggag cagcggctga aggaggccgc
    25501 cggagcacgg cgcacgctcg tcgtcaccga cggcgtgttc tcgatggacg gctatgtggc
    25561 cccgctggag gagatctgcg atctggcgga gcgctacggc gcgatggtca tggtcgacga
    25621 ctcgcacgcg gtgggcttcg tcggccctgg cgggcgcggc accccggagc tgcatggcgt
    25681 gatggaccgg gtcgacatcg tcaccgggac gctgggcaag gcgctcggcg gcgcgtccgg
    25741 cggctacgtg gcggcccggg cggagatcgt ggagctgctg cggcagcgct cccgccccta
    25801 cctgttctcc aactcgctgg ccccggtgat cgcggccgcc tccatcaagg tcctggacct
    25861 gctggaggac gacaccaccg gcgagggcgc cgcgctgcgg gcccgcctct acgccaacac
    25921 ggaactgttc cggcgacgga tgaccgagga gggcttcgag atcctgccgg gcgaccaccc
    25981 gatcgccccg gtgatgatcg gcgacgccga gcaggccgga cgcatcgccg accagctcct
    26041 ggagcacggc atctacgcgg tggggttctc ctacccggtg gtcccgcacg gcaaggcccg
    26101 gatccgggtc cagctgtccg cggcccactc ggcgccggac gtggagcgcg cggtggccgc
    26161 cttctcggcc gcgcgagcgg cactggcaga atgaccgggt gatcgacacc cgcagactgc
    26221 gcacgttgcg ggccgtggcg gaccacagga cgctgaccgc cgcggctgcc gcgctgtatc
    26281 tgactccctc cgctgtctcg cagcagctgg ccgccctcga acaggaggtc ggtcaccagc
    26341 tgctggtccg cgacggccgc ggggtccggc tgacggcggc gggggagatc ctggccgcgc
    26401 acggcaacac cgtgctggcc cagctggagc gggccgaggc cgagctcgcc gcctacgcgg
    26461 cagggcacgc cggcgaggtg acggtggcgt ccttcgccac cgggatcgcc accgtggtcg
    26521 ccccggcgat gacggagttg ggcaccagcc atcccggcat caggctccgg gtgcgcgacg
    26581 ccgagggcga cgccagcctg accatggtgc tggacgggca cgccgacctg gccgtggcgg
    26641 tcgagtaccg gggcgcgcca cgcgaggacg acgagcggct gtcgagggtc ccgctctacg
    26701 cggagccctt cgacgcggtc ctgccgcgaa gccaccggct cgccgacagt gccagtgtca
    26761 gggtcgccga tctcgcggag gaaccgtgga tcggccccta ccccggcaac ccctgccatg
    26821 aggtggtcat gctggcctgc gaattcgccg gcttccagcc ccgcgtgacg cactcctcgg
    26881 acgatttcag ggccgttgcc gcccttgccg gggccggagc gggggtggct ctggtgccgc
    26941 gctccgcgct gcgcggagtg gatctgccgg aggttgtggt gctaccggtc gccggggatc
    27001 cacccacccg ccgggtgttc gcggcggtcc ggcgcggagc ggagcagcac ccgctcgtcc
    27061 gacccgtgct ggatgccctg gccatggctg ccgaccgcgc ccggccacgg gaggacccgg
    27121 ctgaactact cggcctcaac gggtgatgtc cgccgcggca accgcctcga cgaccggtcg
    27181 tcacagcact gggcattcac ctgttccctt ggaaatcgca gcacgcttgt cggaggtttg
    27241 accatgccgt acacccgtgc gcgacgtgcc gttctcggcg gactcgccgt gctcaccgtc
    27301 ctcccgctgg cagcttgcgg ctctggcgat accccggctt caccggctcc gtccaccacg
    27361 gcttcccggc cggatccggc cgggaagccg tccgccggcg atttccagcg gctcgagcgc
    27421 acatacgatg cacgactggg gatctacgcg gtgaacaccg gcaacgggag ggaagtggcc
    27481 taccgggata cggaacggtt cgcctatgcc tccacgttca aggcgttcgc cgccgctgcc
    27541 gtcctgcgca agtactccct gaacggcatg ggcaaggtgg tcaagtactc ccgggccgac
    27601 ctgctgagca actctccggt caccgcgaag cacgtcgaga ccgggatgac tctgcgtgag
    27661 ctgtgtgacg ccgccgtccg ctacagcgac aacaccgcgg ccaaccttct gttcgctgcg
    27721 ctcggtgggc cgaagggcct ggcggccgct ctcgccgagg caggcgacac tgcaacccgg
    27781 gtggagcgcc gcgagccgga actcaacgaa tggacccccg gcgccacacg ggacaccacc
    27841 acaccccgcg catgggccgc caacctgcgg gccttcgtcc tcggagacgc gctcggcaag
    27901 gacgagcgcg cacagctcgc gcagtggctg cggaccaaca ccaccggcga cgagctcatc
    27961 agggccggcg tccccaaagg ctggacagtc ggtgacaaga ccggcggagg cggtgtctac
    28021 gccgtccgca acgacatcgc cgtggtgtgg ccccccaacg ccgcgcccat cgtcatggcg
    28081 atcatgacca atcgcggcac agcagacgcc ccctatgaca acaagctcat cgcggaagcg
    28141 gcgtccgtgg tcgtccggac cctgtcctag tgcgctgcgt ccgaaatccg tcggccctgt
    28201 cggcccggac gaactacgcg atggggaaat caaaataggt gtcgggataa ggttcgtcct
    28261 ggagagtgta atgccaccac tcgtaatcgt aggcgctgaa accgctggcc tccatgatgg
    28321 agagaaggtt ctgacggttt ctcgcttcga cgtgtccgat ctcttttgct ccatgatgtg
    28381 agatgtcgtc catcaagtca tggtcgccgc ccatgggagc gagttcaccg gtggacaagt
    28441 cgtagagggt gaggtcaacg gtgctgcccc ggctgtggcc cgacttcgcg gccacatatc
    28501 ccctctcgaa catctcggcc ctgccgatgt tcggatagtg tcgtgacttc gtccggccgt
    28561 cctccggaag cttcgaccag cgcagaaagc agtcgacggc gcgctggggg cgataaccgt
    28621 cccagagaag cagaccgaac ccaagggatt gggccttctc ccgcgctcgt tccagggctg
    28681 cgcacaaatc cctcgtaccg acaactcgat ttgccatata cccgtccacc ggtttaccgg
    28741 tgaagttctc ccacgtggcg tacttggcgt cccagcgtat tccggacgca agctcgtcca
    28801 caaagacgaa gtcagccttc atcgcctttt tcccgccaat gccagagaca ccgtccggtc
    28861 gatcacctcg gaaagtggca accctgcggc cgccatcatt ctcggatagc gactgtacga
    28921 ggtcaggcct ggcaaggtgt tgacctcgtt gaggaccact tctccatcgt ccttgaggaa
    28981 catgtccacc cgcgacagtc ccctgcatcc caaggcgcgg tatacggcct ttgccgtctc
    29041 ctgaacgagc aatcgtgact cttccgggat ggcggcggga acgatgaccg ctgagttgtc
    29101 ggaaccggtc tccggctggt cctcctgatg gatcctgaag aagccgtggg agagagcgat
    29161 ttgatccacc tcgcccgcga ccagatcctg atcgttcccc aggatggcgc atccgatctc
    29221 gctgccgacg acagcctctt cgatcaagac cttcgagtcg tactgccgtg cgacgtccac
    29281 cgcactcagg agttctcctt cccgggatac cttggtgacg ccgaaggacg accccgaacg
    29341 ggccggcttc acgaagaccg gataggtgag ccggccggga tcgatctttt cgtccgccgt
    29401 gatggtccag aagttcggcg tggcgattcc cgcgcttccg gcgacgatgt aggcaaggga
    29461 tttgtccatg cacagaacag aactctggac gtcgcagccg acgtagggga tgccggagag
    29521 ctccagcaga ccctgcatcg cgccatcttc gccgagtgtg ccatgcagaa cgggcaacac
    29581 gacgtccagg cggatcgtct cgtatcgccc ctgctcctgg accagcagtc cgtgcacgct
    29641 gctgtccggt gacagcacag cagggcggca gttgccgttc tcccaatccg cgtcgggccc
    29701 gtcaccgagc ttccaggcac cgctcttcgt gatcccgatg tagaagggct catacttttc
    29761 gatatcgagg tgtcgtgcca cctctcgcgc ggacttgacg gagatggggt gctcttcgga
    29821 ccgtcccccg aagatgattc cgaccttcaa cctagccatg ctgattcctt ctttcgaatg
    29881 ccagacagtt ggtgagggag ttttccaccg tgtcgctcag ggcgtggtcc gtgtagtagg
    29941 cggtgtgcgg actgatgacc acattcggca gctcttgcag ccgcaatagc ggtttgctct
    30001 ccatgggtct gtcccggcgg tcggcgtaga atattccttc ctctccttcg aggacatcca
    30061 acgccgcacc gcccaacctg ccgctttcca atgcctgcac aagggcctcg gtatcgatca
    30121 gcgcaccacg cccggtgttg acaatcagcg caccgtgctt catcagctcc atacgctgcc
    30181 gattcagcag atggtgcgta tccgcgttga gcggtgcatg gagtgtgacc acatcgctcc
    30241 gccgcagcaa ttcatcgagc ggaacgtagt cggcaacggc cgtgggacga ttgtcatggg
    30301 caaggattcg gccgccgaaa ccccgtagtc tgtccatgac cgctgcgccg atgcggccgg
    30361 tgccgatcac cccgacggtc agatcacgta gctctttccc gcgcacgtca ctcaatcggt
    30421 agtcgtgcag gtccgagcgg cggatgatgg atttcatgtc ccgaagtgcc atcagcatca
    30481 acatcaacgt gtagtcggcc acactgtctg ccgagtagct gacgttttcc actgaaatgc
    30541 cgatgctgtc cgcgtactcc acatcgatat ggttgcagcc gatgctccgc gtggagaggt
    30601 acgtcacgcc ggcttggcca agcgcgagaa gagtggcgtt ggtgacctga gtcttgtggc
    30661 cgacgctgat gcatcggcat ccggatgcca gttcactatt ggcttcggac accggtgcgt
    30721 ccgtgatggt cagcgttacg ccgaagcgcg gcgccagctc tcggaacaga acggcctcat
    30781 ccgggccaca cccgtaaatg gtgatgtggg ccggttcgct gtgggtcatg cctccagtca
    30841 aggcagtgtg acgttgccgg aacgtatggg gttttcgata tgccggcgat acaccacccg
    30901 gccttcaatg aaggaatgcc cttcgacgaa acagcctccc gcagcctctg ccctgccggc
    30961 ctgctcccgc tcggcggccc ccgcgccgcg cggtcatgat cccgctcagc ctcggcgaga
    31021 tcgccgaggt cgtcggcggg agggtccagg gcgacagctc cgtgacggtg accgcgccgg
    31081 ccgtgctcga cggccggcag gtcgagccgg gcggcctctt cgtcgccttc accggcgagc
    31141 acgtcgagcg cgggcggcgg tgccggccga caacgacgcg gccgtccact ggctgcgcgg
    31201 ccacgtcgtc gccggcgatg tggtgctcat caaggcctcc cgcggggcgc acctcgacat
    31261 ggtcgccgcc gcgctcgcct gagatgcgga ctcatcgccc gcgcctcata tagagatcga
    31321 aagcccggta gaccatcggc cgtagcggca ggtcccactc gccgacgtat ctcaccgcct
    31381 gaccgccggt gccgaccttg aactggatca gtccgacgtg cgggtcgtcg gcgtcgaggg
    31441 tgggggtgac gccgcgcagg tcgtagacgt cgcatccggc cgccagcgcg tcgcggatca
    31501 tcgcccactg gcaggcgttg gagccgcgga cctcgcgctt cccggtggag gaggcgccgt
    31561 aggagtacca ggcgcgggcg cctacgcgga ccaggatggc ggcggcgacc ggatcgccct
    31621 ggtggtgcgc cagatagagc ttgatccgct cggggtcctc ggcgctcagc gccgcgaaca
    31681 tggtctcgaa gtagcgcagc ggccggggcc tgaagcggtc gcgctcagcg gtgtggatgt
    31741 agaggtcgtg aaatgctttc aggtcctcac cgaccgtgac ctcgactccc tccttggccg
    31801 ctttcttgat gttgcggcgc cactgctggt tcatgcccct gagcacgtcg ccctcggtcc
    31861 tgccggccag cggaacctcg tacttgaact gcggatgccc gaccccgaac ccgtcctccg
    31921 ggctctgcgg cagccagccg gcatccctga gccggctggt cacgtgggcg ccgacctggc
    31981 catccccctg actccgcagc tcggtcagcc gctggacgcc cgggtcggcg ataccctcct
    32041 tgatctgggc cgcgctccag gagtccgtgc acaccggcgg gccgagccgg atcgcgaacg
    32101 cgccgtgcgc cttgaggtac gccgccagcg ggtcgagcca cgcgtcgatg tcgccggccc
    32161 agtcgatgac cgggccctcg ggcagatagg ccagcgtgaa gcgctcgaac cgcggcaccg
    32221 gtcggtgcag gacgagcccg gcaccgacca gccgccgacc gtcgaaccag ccgagggact
    32281 cgctgcgcca ctcggtcttg acgcggcccc atgccggggt ctgcaggaag ctgaccgacc
    32341 gctgggcccg cacgaactcc aggtgctcgg ccgcgctgat cggcccgacg gtcggcctca
    32401 cgcccgcccc ctgccggtcg accagctgat gccggccgcc accggcaggt ggtcactgcc
    32461 ggtggccggc agtgaccacg aacttctcgg ctggacaccg cggaccagga tctggtcgat
    32521 ccgcgccacc gggaagttcg ccggccagct gaagccgaag ccgtccccgg ccgcgtcctg
    32581 gaccgagcgc agctgcgagg tgatgccggc gaacgctcgg tcgtcgatgg tgccgttcaa
    32641 gtcgccgagc agcaccaccc gctcgttccg ctcggcggcg atggccttgc cgagtgcctg
    32701 cgcgcctctg tcccgcgagc ctgtccaaaa gcccgccctg ggattcaccc gcacggaccc
    32761 caggtgggcc acgtacaccg ccaacggccc gtggtcggtg ctcaccgtgg tgcgcagcgc
    32821 ccggttgtag gccatcttga cctccatcgg cttggtgtcc cccagcggac cgtagtccgt
    32881 ctcgatgtcg accggccggg tgtcggacag tggcagcttg ctccacagtc cgaccgttcc
    32941 ccgcaccgtg tggtgggggt acggcttcgc cagttccttc tcgtacgtgt tcagggcctg
    33001 cggtgtgaac tcctccagtg ccagcaggtc cgcaccggag gcggccaggt cgcgggcggt
    33061 gccggccggg tcggggttgt cggcgccgac gttgtggctc accacggtga ggtcactgcc
    33121 gtcgtgggac ttgtcgacca gcatcccgcc gaagagggtc agccacaccg tcaccggcag
    33181 cagcagcgcg accaccgcag aggcggagcg gcgccacagc gcaccggcca gcagcagcgg
    33241 gatgaacccg ccgaaccatg gcaggaaggt ctccaccagg ctgccgagtc ccacggtccg
    33301 attcgggatc ttcgcgtgca gcagcatgag caggccgagg agcagcgcca gtgccgcgag
    33361 caccaggccg cgcttccaga accccgcccg gaagccgaat ggggcatccc ctgctcgagc
    33421 ccaacggaga actcggggaa ggatcgcccg gcgaacgccc gcgcgccagg tcccgcccgt
    33481 gccggccgcc ggaacacccg ttccggtacc tgtcgcgcgg gtatcccccg ggctgtcctg
    33541 cgctgtctcc gctgttggtg gggttcggct cataccgcca gtcaaggcgg cgcggtgttg
    33601 cccgcacgta tgcggatttc gatacgccga cgatatgcgc cgacccgtag cctgaagaac
    33661 atgcgtgtgc tgatcgtcga ggacgagccc tacctggcag aagccatccg cgatggtcta
    33721 cgcctggaag cgatcgccgc cgacatcgcg ggggacggcg acaccgctca ggagctgctg
    33781 ggcatcaaca cctacgacat cgccgtcctc gaccgcgaca tccccggacc gtccggcgac
    33841 gagatcgcca aacgcatcgt cgcctccggc agcggcatgc cgatcctgat gctcaccgcc
    33901 gccgaccgtc tcgacgacaa ggcctccggc ttcggactcg gcgccgacga ctacctcacg
    33961 aaaccgttcg aactacagga actcgtgctc aggctcagag cactcgaccg caggcgtgcg
    34021 cacaccaggc ctcccgtacg agagatctca ggtttgcgcc tggatccgtt ccgccgcgag
    34081 atctaccgcg acgaccgcta cgtcgcgctc acccgcaagc aattcgccgt gctcgaagtc
    34141 ctcgtcgccg ccgaaggcgg tgtcgtcagc gccgaggatc tcctggaacg cgcgtgggac
    34201 gagaacgcgg acccgttcac caacgccgta cgcatcacgg tctcggccct gcgcaaacgc
    34261 ctcggcgaac cctggatcat caccaccgtg ccaggcgtcg gctaccgcat cgacacgcaa
    34321 cccggggccg tccacggagg agaagaccgt ggatagggca cctgggatga gcgttcgcct
    34381 caaactcacc ctcagctacg ccggattcct catggtggcc ggtgccttgc tgctcgcggc
    34441 cgtgtgggtt ttcctcctcc gttatgtccc ggaccgtgcg atgctcatca accctgatga
    34501 caagcccacg catggtgtct ttcccatccg gtccggcctc cttaacgtct tcgcgccgag
    34561 agcggccgca gtactggcga tcctgctggt gttcggcctc gtaggagggt ggatcctcgc
    34621 cggccacatg ctcgcccccc tgacccgcat cacacacgcc acccgcatgg ccacgaacgg
    34681 atcactttct caccggatcc ggctaccggg cagcaaggac gagttccgcg aactcgccga
    34741 cgccttcgac gccatgctcg cgcgtctcga agagcacaac gccgaacagc agagattcgc
    34801 agccaacgcc tcccacgagt tgcgcacccc gctggcgatc tcgaaggcac tgctcgacgt
    34861 ggcccgcacc gatccgaacc acgacaccgg tgaactcgtc gaccgcctcc acgccgtcaa
    34921 cacccgagcc atcgacctca ccgaggcact gctcctgctc agccgcgccg gtcagaggtc
    34981 cttcacccga gaaccggtcg acctgtccct catggcggaa ggagccaccg agacactcct
    35041 ccccctcgcg gagaagcatg gcgtcaccct cgaaaccagc ggcgacgtcg ccccggcgaa
    35101 cggatcgccg gcactcctgc tgcagctgac cacgaacctc gtacagaacg cgatcgtcca
    35161 caacctgccg gaacacggca gcgtatgggt ccacaccagc gtcggcccca acaccgtggt
    35221 actcaccgtc gaaaacaccg gcgagcagct ctcgccgcac ctggtctcga cgttcaccga
    35281 acccttccag cgcggtactg agcgcatcca caccgcccgg acaggcgtcg gtctgggcct
    35341 ggccatcgtc aaaaccatca cccaggcaca cgacggaacc ctcaccctca ccccgcgctc
    35401 tgccggcggg atccgcatca ctgtggaact acccgcgaca tccccgtgca ccgacgggtg
    35461 aagaactgag cgggtgctgg gacctgacca caaccggcgg agtcttccgt ggctcagccg
    35521 ggtcggaagg agacccggac gttggcgtcc aacgggatga tcagcacgtt tccgcgatcc
    35581 acagtccagg actgcggaat gatgaacatc cggtcgccgg actgggcaag caagcgcagt
    35641 ccccggtagc ggaacctgaa gtgttgctgc ggtgtgccct cgggaaggac ggtctcctgc
    35701 actcccgggt actggaagta cagccgctcg gtggtgtcga gcaccacctg cggtctgagc
    35761 cacagacggt ccgtcagata agcagcgtcg cttttgccat ggtcctgggc atagatgttc
    35821 accgtccaga acgacgagag cacgatcagc gcggcaacga tggccagcgc ggccttctcc
    35881 cgtaggaccg ggtaccggcc gccggaaatc ttgacgagga gcagtctccc gtacatcagc
    35941 accaccagac caccgcccag gaacagcggt gtccccagcg agccggcgta gagcacatcg
    36001 aacccgcaga gcagcccgac gaggaagagc agcagcccgc acgcgatcac ggcgagcgaa
    36061 gcccaacgga cgtacggcgg ggtgggcgcg tccgaccggc cgagtgacgc gaccaggtag
    36121 tacgcgagca cccccagcaa tccgacgacc agcgccgccc cgatgggcag gaagagcgcg
    36181 ccgccactgc gcagggcgta gtcctgggtg gagaagccca gggtggccgc gtcgatcccg
    36241 aactgctcgt acagcgcgtc ggtgtaggcg aaaccgaagt agagcagcag cgccccgatg
    36301 agcgtggtgg gtgcgaccag cgtggtgagc gtacccagcc aaccggccca gggtgaagga
    36361 cccgcttcgg gctcaccggc atcgcccccg ttcccgccgg tgccgggatc ggcgcccggg
    36421 tcgggaacag gggccggggc agggtccggg acgggggccg gctcgggggc cggatcggcc
    36481 gggctcaggg tgtgctcgcg tcggacgtcg cgggtccttc ggagacatcg ggggtatcgg
    36541 gggtgtcggg gctgtccggg gtatcggggc tgtcgggggt gtcagagggt acgggcgggg
    36601 cggacgaggg cggatggatc ggatcgctga acgtggtgac ggggccgccg ccgtcctgga
    36661 ccagggtgcc gcacatagtg tgcgtaatgc gcggtgcagt ggcggcgaga tggaattcgt
    36721 cgaagtagct cgcccccggc gccaccgaga tgtgtctact caccgactgg gccggctgcc
    36781 cgggggtgca gtcatggaac tccaactgcg cttcgtaggc ggctccggtg gtgttattca
    36841 catccacatt gaccgggttg ggccactgcc cggagaattt ggcggacggt ttgggaccgt
    36901 ccttgaagcc gccgttcggc ttcgcagttc tttttgaccc tcgctggact cttccgagcc
    36961 ctccaccggt ggggttgcgt tcgggtcgag agactcctcc gaagtggcgg acgtcccgcc
    37021 ggaggggctg tcgttgccac cacctgacga gcatccgagg agcagcgggg ccgctgctcc
    37081 gagcagtggg accactgcca ggaatcgcct gccgctcgcc gcgagcatgg gccgggacca
    37141 gtccatagag cctccgagac tgaggggacg gacggaccga aagtagaccg ggggcatagg
    37201 cgatgggcac gcacaacacg gcgtcgaggt ggaatttcac gcgtccgggc gctacgccct
    37261 gcccggcggg gaggccggcc ccttgggagt cgcgtccccc ttcggggccg cggggtcatc
    37321 ggagtccgga acctctgacg cgtcggcgtc aagttcgcgc atgcggcggt gaatcgcctc
    37381 gcgcgggttg gctgcacgag gctcttcgtc ttccggcggt tcctctggtg tccgaccggc
    37441 tttggaccgt tcgatcagcg catggatccg atccgcgcgc gccttgctgt cctcggagcc
    37501 cacggagccc tccgaactct cgggattctt acggcccttc gggtccttgg ggcctttggg
    37561 gtccgctctc ccctcaccca tggtccttgg ctccgccttc ccaggtgcct tccagggtct
    37621 gacctgactg gagaccctga atctgggtcc gccaggcgtc ggcgcgtgag gtggtggact
    37681 tcttgaccag cgcggtcagg gtctgtgctg aggtgaagcg gtcggactgc ggaccgctgt
    37741 cggcgatgcg tagcgccgtc ttggtgcggg aatcgatggc ggagcgcagg ctgcccgcgc
    37801 gggcggtcag ctttccgagg tcgcggaact ggggcttggc ggtgtcgaac cagacctgct
    37861 gccaccagtg gtcggtgacc ggttcccgcc aactgaggta tccgccgggt accgccggcg
    37921 cttcgcatcc gaggaacgga gtccgggccg agtcgttcaa gtccgtcagg tcaggaggtc
    37981 ggagagctgg gctccgaagt ggtcgggcag gttggcctcg tcggcgagga gggcgaggaa
    38041 ggcggtgtcg gacgaggcgg tcaagccgtc gagggacagc gggacgagcc cgtcctgccg
    38101 cgcaaggcgt gttgcgatct gcggccccgt cggctgcccg ccgttgccgc gcagtgccag
    38161 gcgtgggcgc agctccgcgc cggtgggtcg tatctcgtcg agtgcgagct gccagtgcag
    38221 gtcgccgtcg ggccgggccg tcacccgcgg ctgcgcggct cgtgctgcca gcgccggcag
    38281 gtcgtgcagc gcgtgggaga gccggctggt ggcctcggcc agcgtcaccc cggcgacgat
    38341 cgggtcggcg gaatcctgct ggaggttgag tacatgatcg gcgggggcgc ccgtggccgt
    38401 gtcttccagc ggcgccccgg gagccagggc cgtcatgagc cggcgggtgc cgtagcgggc
    38461 gacgccgtcg atggtgacga ggcggatgtc ctcgtcaccg gcgtcgatca gggatccgta
    38521 gggatcgccg gcagcgccgg agatggtgag caggtcggcg cgcatgccgg gccgcagcga
    38581 gccgagggtt tggtcccact gcagaatcgt ggccgcgtcc cgggtggcca tggcgaccag
    38641 ttcgcggtcg gagaacactc ccccagccgc gtcggatgcc agacgggcgg ctttgagttc
    38701 accgagcagg cctttgcttc cggagatggc ccagtccgag cccagtccga tgagaacgcc
    38761 ggcctgtttg gcggccgcga tgtcggcggt cttcccgtac agcagcaggt tggacagcgg
    38821 cgaccacacc atcgagccgc cgtggtcggc gagtatccgg aagtcttcgc ccgtcagcgc
    38881 ggtgcagtgg atgccgacca ggttctccgt gatggcccat tggcccggct ggaactccag
    38941 agcctggaag tgcgcacgcg cggcagcgtc ggtgccctcg gccagatgca gcaggagccg
    39001 gtgcggctgc cgcagccggg ccaggaaccg ggccgcgtcc accgcctcga catcggctat
    39061 ccgggagccg gcctccggca gcgcggggtc gtcggtctgc tcgacgttgc gaacgatccc
    39121 ccgatacatc cggcgcgccc cggcgttgct gaacagagcg atgccctgac tcgtcgtcgt
    39181 cccgttgacc agggccttgg cctcgacgta ccgcaccacg gcgggcatca gccggggatc
    39241 ctcgccgagc accgtcatcg gtccggtcac caggcggtgg tagtcggggt tccggctacc
    39301 gccccactgc gaccggttgc tgtacttctt gggcaccggc cacaactgca gaacgtcgta
    39361 gggcagatgg ttgtgcagtt cgatcagacc ggggtatatc gtgccgccgc tgacgaccgg
    39421 accgatgtcc tcgaaccccg gcggtgcggg cgccccggca ggctgcaccg cctctatcac
    39481 gctgtccctg atgtacagaa caccatcggc gacgacggtg ttgtgcgggt cgagggtgac
    39541 aagccgcccg cgcagtgcga acggtgaggt gtccggggcg ttggctgggg gcggcatagg
    39601 tgcgtccctt cgctgcgccc acaagggacg accgtcgaag cgttcgggcc aataccatgg
    39661 ccctcttcca gaatgccgtg cgcctaccga tatgtcacca tttggcatat ccattcgccc
    39721 acctggagta ggagccccac gtgcatgaat tcgacccggg ctacgccctc gagccctatg
    39781 cgaccctggc gcgctcctac ccgggcccgg aggtctatcc ggccgaggac ttccgcatcg
    39841 agtggggccc gatcttccac cgtggacggc tcgacggcac cgcccgcgtc ctggtcctcg
    39901 gccaggaccc cgccgcccac gaagccatcg cccgccgcat cctcgtcggc accgccggcc
    39961 gccgcttcca gggcttcctg ggcaagctcg gcatcgacac cagctacgtc atgatcaaca
    40021 cctatctgta cagcgtgtac ggccagcacg ccggcaacgc gcacgccacc gacccggaca
    40081 tcgccctcca ccggcacgcc tggctcgacg ccctgacggg gcacaacccg atccaggccg
    40141 tcatcgcgct gggcagcctc gccgacaccg ccttccacac ctggcgcaag accccggcag
    40201 gcgccgcctt caccggcgcc taccagcacg tgctccaccc cacctacccc gacagcgccg
    40261 ccgcgtccgg cgccgacccg gtcgaggcga tgaccaagct cctcaccagc tggaacacgg
    40321 cgctcgacgc cctccacggc acggtcaccg ccgacaccga ccgaccgttg gtccgctacg
    40381 gcagcatcct gacagccgcg gacctcgcca ccatccccga agccgacctg ccgccgggtc
    40441 tgcccgcgtg gatgcgctcc gacgagccat gggccgcccg aaagggggcc acttccgccg
    40501 agaagcgcgc cacgatcacc gtgcggatcc cggaggacct cagacctttc tgacgcggac
    40561 cctgagtgac cgcaggacac tcctccttcg gcttactgag cagatgaggg ccggagtgcg
    40621 tactccttgg catgctcctc gccgcagttg tctccctctg tgtctccctc tgtgtctccg
    40681 cgcagtgtgt tgccgctcgc cccgtgcggt cggtacgggc acggcttcgc gatgagagga
    40741 caacgcgagg tagaagcctg gggcgcatcc tcctgttgtt gtgcgtcgct gtgggggtcc
    40801 tgctcggcgg ggccggctct gccgcctcgc acgcggtact ccgtgggagc gacccggcgg
    40861 acggtgccat cgtcaagaga gcaccgacgg tcgtcaccct caccttcacc gagggagtca
    40921 cggtctccga tgactccgtc cgggtgctcg accctggcgg tcggcgcgtc aacgagggac
    40981 ggcccaggca tgccgcgggg aagtccggca ccgtgcagac cacgctccgc gggaacatgc
    41041 ccaggggtac gttcacggtc gcgtggcgcg tcgtgtccgc cgacagccac ccgatctccg
    41101 gcgccttcac cttctcggtc ggcgagcctt cggcgacgtc ggcgatcgtg ccccggtcgt
    41161 cggccggcga cacagccgcg gggcg
//
