LOCUS       NZ_CP048835            22661 bp    DNA     linear   CON 17-MAY-2024
DEFINITION  Streptomyces sp. So13.3 chromosome, complete genome.
ACCESSION   NZ_CP048835
VERSION     NZ_CP048835.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. So13.3
  ORGANISM  Streptomyces sp. So13.3
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Quezada-Solis,D., Khalil,Z.G., Capon,R.J.,
            Andreote,F.D. and Barrientos,L.
  TITLE     Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed
            Culture and Elicitation Conditions for the Production of
            Antimicrobial Compounds
  JOURNAL   Biomolecules 10 (5), 673 (2020)
   PUBMED   32349314
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K., Lamilla,C., Abanto,M., Maruyama,F., Jorquera,M.A.,
            Santos,A., Martinez-Urtaza,J. and Barrientos,L.
  TITLE     Antarctic Streptomyces fildesensis So13.3 strain as a promising
            source for antimicrobials discovery
  JOURNAL   Sci Rep 9 (1), 7488 (2019)
   PUBMED   31097761
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9564008)
  AUTHORS   Nunez-Montero,K. and Barrientos,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-FEB-2020) Centro de Excelencia en Investigacion
            Biotecnologica Aplicada al Medio Ambiente (CIBAMA), Universidad de
            La Frontera, Av. Francisco Salazar 01145, Temuco, La Araucania
            4811230, Chile
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-JAN-2020
            Assembly Method                   :: Unicycler v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 140.0x
            Sequencing Technology :: Illumina MiSeq; Illumina HiSeq; Oxford
            Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005860785.2-RS_2024_05_17
            Annotation Date                   :: 05/17/2024 04:03:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,707
            CDSs (total)                      :: 8,616
            Genes (coding)                    :: 8,274
            CDSs (with protein)               :: 8,274
            Genes (RNA)                       :: 91
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 342
            CDSs (without protein)            :: 342
            Pseudo Genes (ambiguous residues) :: 0 of 342
            Pseudo Genes (frameshifted)       :: 109 of 342
            Pseudo Genes (incomplete)         :: 268 of 342
            Pseudo Genes (internal stop)      :: 24 of 342
            Pseudo Genes (multiple problems)  :: 52 of 342
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:45:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 68930
            Orig. end                         :: 91591
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP048835.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Laboratorio de Biologia
            Molecular Aplicada, Universidad de La Frontera, Avenida Alemania
            0458, Temuco, Chile.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22661
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22661
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22661
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12661](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12661)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(9..1256)
                     /locus_tag="C8250_RS00355"
                     /old_locus_tag="C8250_000355"
     CDS             complement(9..1256)
                     /EC_number="2.8.3.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550898.1"
                     /locus_tag="C8250_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000355"
                     /product="CoA transferase"
                     /protein_id="WP_244808913.1"
                     /transl_table=11
                     /translation="MAQVNAKIDERDHLSMFDPEASGSGPLDGCLVIELSHALAGPHAA
                     MMLGDLGARVIKIETPGHGDEARSWGPPFVGPDQTPESTYFLSCNRNKESVTADLKTEQ
                     GRELLTRLLRQADVLVENFRPGVLERLGFPLQQVRETYPTLVVLSVSGFGHDGPHAGRA
                     GYDQIAQGEAGLMSLTGEPGAPAKVGTPVADLLAGIFGVTAVLAALLERHTTQRGQVVR
                     TSLLSAVVGLHSFQGTSWTIAGKEPSATGNQHPAIAPYGLFHCADGDLQLAAGSDRLWR
                     NMAAVTGLDPADPRYTTNADRVRHRTDLATALNAVFAHDTVDAWIERLDAVGVPVGRVR
                     TLAEVYAWEQTRQQGLLIDVDHSTLGTITLPGPPWRFETGGRSRHTAPPTLGQHTTSVS
                     AWLDRSDPPAPPRAPG"
     gene            1736..2449
                     /locus_tag="C8250_RS00360"
                     /old_locus_tag="C8250_000360"
     CDS             1736..2449
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009081473.1"
                     /locus_tag="C8250_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000360"
                     /product="response regulator transcription factor"
                     /protein_id="WP_138358120.1"
                     /transl_table=11
                     /translation="MRRALAELLIVEDDAEIASELDRALVGHGYQVVHAATGGQAAEQA
                     RRRPPDLVLLDLGLPDVNGVEVCRRLRAFLPVETVIVVLTARTLEFEVVVALDAGADDY
                     LTKPFRLTELLARLRAHLRRRATAAGPPVMRIGGTRIDTQTRRVHIGDREVHLRPKEFD
                     LLATLAASAGAVVSREHLMAEVWDEHWFGPTKTLDVHVSALRRKLADADERGGECITTV
                     RGKGYRYETDKSPVS"
     gene            complement(2442..3842)
                     /locus_tag="C8250_RS00365"
                     /old_locus_tag="C8250_000365"
     CDS             complement(2442..3842)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="C8250_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000365"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_138358118.1"
                     /transl_table=11
                     /translation="MSSVDGHVILGRGFVGSSVRGRVMVSIVAVTACAVLVFTVPLAIA
                     VDRIYRDGAVACLERDAIWAAASLSGGTGGAPDRLVTLHPPSHGVHVGVYSPLGRRVHG
                     SGPALSPGAASSRDGSLHRGVEGGNLAVFAPVVQGGTVREVVRAWMPWDPVADSTMLAW
                     LLLAAVGAVVVALAALLAWRVAGRVATPLERLTASAQALGSGDFSIRPECTGIREADAA
                     WQALATTAGRLGALLERERRFSTAVSHQLRTPLTALVLGLDTAQSLDDQGRGRALVTAL
                     RRAEHLGDTIEDLLRLARETHHQADIVEVEGLLNDIARRHRDAIGEAGRRLTVRCEAGL
                     PPVSASAAAVAQIMGTLMDNALVHGRGEVRLSATDVGAGVALEVGDDGPGPAGDGDAVF
                     GTVRRDGQRHGIGMPLARSLAEAEGGRLLLRRPGPRPVFSLLLPACEPLPATDAGSCES
                     LPGRSTVN"
     misc_feature    complement(2499..2501)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(3306..3308)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    3802..3819
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            complement(4022..5092)
                     /locus_tag="C8250_RS00370"
                     /old_locus_tag="C8250_000370"
     CDS             complement(4022..5092)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024629.4"
                     /locus_tag="C8250_RS00370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000370"
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="WP_187144659.1"
                     /transl_table=11
                     /translation="MDKLPGFLWPQAVSARLFGFHPWALALSQVIEGALSVLVLFRLVR
                     RQAGAHAALVAAAAFASTPAATGLFRSTVEDAPFTLFLLLAADAAFRASSTARQRPLIW
                     SAVWVGLAFQAKMLEAWALGPVLAALFLVVAPMTLRRRNRFPQLGLSPADTGSVNSVPS
                     GPVAKRSVGGGAGTAAATGDEGGWTKMVRAPLASQTGWLYPAAALTLGCGLVWLRRRPR
                     SDPERAALLLWGGWLTTFLAVFSAGTVAGHTYYMGVVAAPLAALTGIGTAQCWRAHLAG
                     GSRAWMLPTMIGGTAVWSAVVAGVWPRFWPGLGSAVLVLCSAGLILLAWSRPSGAGPGH
                     RGGHRVALAGLLLGGG"
     gene            5644..6231
                     /locus_tag="C8250_RS00375"
                     /old_locus_tag="C8250_000375"
     CDS             5644..6231
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="C8250_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000375"
                     /product="response regulator transcription factor"
                     /protein_id="WP_244808914.1"
                     /transl_table=11
                     /translation="MIRVLWVHDSQLMRSALAALLDDERDMQAVTSCWKNATARAKALR
                     PQVCVVDGDCPGSSRLPTRPAQRDCALVVLTRQFRPGVMRWATEARALGFVDKDAPPST
                     LLSAIRQVAAGERYVDRSLAFDVLQAAAIPLSPRELRVLALAAGGASVPEIAESLRLRE
                     GTVGNYMSAIIRKTGGRNRVDAIRISQEAGWV"
     misc_feature    5824..5826
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6061..6063
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6251..7996)
                     /locus_tag="C8250_RS00380"
                     /old_locus_tag="C8250_000380"
     CDS             complement(6251..7996)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551013.1"
                     /locus_tag="C8250_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000380"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138358114.1"
                     /transl_table=11
                     /translation="MTGSRTSVRSRAWSFLRARARVLLLLAGWSLLESAQTFLSGYGVA
                     RALDNGFLAGRTDTGLWWLAAAAGAIVVSGLATRQVFRGLADLVEPLRDGLVRSVVTRA
                     VTRSLDDSGRAADSAAVSQLTNQTEMARDSFAGLVLVARSFVFTAVGALVGLASLDTQL
                     LLIVLPPLVAGLALFLATLAPMAARQEAFLRADEALSARFGTIASGVRDVVACGSQGAV
                     AGDTHRMIDAEADAARSLARWAAVRTLALGIAGQLPIGLLLLCAPWLLDRGLSTGSLLG
                     ALTYLTQALLPALHTLMNALGAAGTRLLVVLRRLTDDTPPGHASIVGRSVAPAAGGQER
                     PVGKVEVTGLTFAYGPEAAPVLCDLHLTIEAGEHWAVVGPSGIGKSTLTALIAGVLTPD
                     RGRITVGGCEASLATGEDPSLRRVLIPQQAYVFTGTLRENLLYLCARGAPAEAVRASVQ
                     AVGLGPLARRIGGLDAPLDPASLSQGERQLIALGRAHLSPAPLVLLDEATCHLDPAAEA
                     QVEGAFAQRFGTLIVVAHRISSARRADRILLLDGIHATQGSHQELLAASALYQDLVGRW
                     HASHL"
     gene            complement(7993..9762)
                     /locus_tag="C8250_RS00385"
                     /old_locus_tag="C8250_000385"
     CDS             complement(7993..9762)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471139.1"
                     /locus_tag="C8250_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_138358112.1"
                     /transl_table=11
                     /translation="MASPRTTPVPASATTAPAGTAGPGPALTGALRHSARHAVTVLACS
                     TASAAAAVALPAVLGRTLDLILAHAAGAGRSIALCLALIAAEVLLDSVVALSGGVMTAR
                     STAWLRRRGTDRLLSLAPHQAAERFPPGDLVARLTGNAAEAGAAPVTAATGLAALLTPI
                     GGLLALALTDWPLAVVYAAGLPVFALLLRAFTRTSSDSVTRYQAVQAELANRLVETLAG
                     ARTVAAAGTERRERARILAPLSELNTQGRRMWQVYGRAVASSSILVPLLITAVLALGGL
                     RLAAGHLSVGQLLAATRYAALAAGLGGVLGQLNTLIRSRAAAARTLAILEVPAMRGGHR
                     ALPADGPGTLELRAVTVHRAGVPVLRSVDLTVPGGTTMAVVGRSGAGKSTLAAIAGRLA
                     DPDNGQVLLDGVPLEETDPAQLRREIGYAFERPTLFGDTIGAALAFGPYTPTGRQIEAA
                     ARAADADQFIGRLPGRYACRIQDAPLSGGELQRLGLARAFAHAGRLLILDDATSSLDSV
                     TELHVGRALAHEVMPGTRLLIAHRVSSAARADQVAWIESGRVRAVGTHQQLWREPGYRA
                     VFADPEHDDEPGP"
     gene            complement(9873..10004)
                     /locus_tag="C8250_RS00390"
                     /old_locus_tag="C8250_000390"
     CDS             complement(9873..10004)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="C8250_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000390"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_138358110.1"
                     /transl_table=11
                     /translation="MTLLDLQTLETPAAEDMGELATGGSRASLLLCGNSSLSVTTCN"
     CDS_motif       complement(9939..10004)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQTLETPAAEDMGELAT"
                     /locus_tag="C8250_RS00390_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9873..9938)
                     /prepeptide="core"
                     /locus_tag="C8250_RS00390_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="19.70"
                     /molecular_weight="1914.1"
                     /monoisotopic_mass="1913.0"
                     /core_sequence="GGSRASLLLCGNSSLSVTTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQTLETPAAEDMGELAT"
                     /leader_location="[9938:10004](-)"
                     /alternative_weights="1932.2"
                     /alternative_weights="1950.2"
                     /alternative_weights="1968.2"
                     /alternative_weights="1986.2"
                     /alternative_weights="2004.2"
     gene            complement(10001..12661)
                     /gene="lanKC"
                     /locus_tag="C8250_RS00395"
                     /old_locus_tag="C8250_000395"
     CDS             complement(10001..12661)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142173.1"
                     /locus_tag="C8250_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000395"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_138358108.1"
                     /sec_met_domain="micKC (E-value: 3.2e-235, bitscore: 782.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.1e-10, bitscore: 40.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-07, bitscore:
                     28.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEGYAVFCDADRQFYDAPYRLSADGRGRGAMYPPLGRELPDGWQ
                     QHRSGDWLAFRPVETNLPFQGWKIHVSACLDNAESILSRVWDYCVPRSIAFKCMPSRYL
                     LHTRNAKYGDRSGSGKFITIYPTDDEQFRTAAEDLNTLLGAEPGPYILTDLRVGAGPVY
                     VRYGSFTERNCYDDQGRSCPAIEDDQGRLVPDRRDPTFHVPQWVTLPKFLRPHLEARAA
                     ATVTDLPYRFERALHFSNGGGVYVGTDLRTDARVVLKEARPHAGLAADEADAVTRLERE
                     RDALLRLTGLGCTPEVHDWFTVGDHQFLALEFIEGRPLNSFFAHRHPLIEPDPSPESLA
                     EYTAWARRVYGLVEQAVAAIHSRGVVFNDLHLFNIMMSEDESSVVLLDFEAASVDDVNS
                     RQVVANPGFVAPADRRGFTVDTYALACLRLALFLPLTSLFAVDRAKARHLAEIAAEQFP
                     VPRAFLDEAVEEIVRGHSAPHPRSGGAASAEASYLPVALGDWPASRDSMAAAIAASATP
                     DREDRIFPGDIAQFSVPGGGACFAYGAAGVLHALAETGAAPSPVAEEWLLRTTKSPASG
                     TPLGFYNGLAGVAWVLERLGHRERALDLADLITSQNWDGISPDLHGGLAGIGLALDSLA
                     ASTGEGALRDHALRCAQLAADTTPQAAGGRPTVRAGLLHGATGTALMYLRLYERSGDGG
                     LLDLAAEALRHDLARCVRAVGGTLQVDEGRRTMPYLGAGSVGIGMVLDDYLPHRYDTRF
                     DQARGEIVQAAQAKFYAQPGLFRGAAGMVLHLARTTTGGPGTHSADLRRQIDSLAWGAV
                     PYQGHLAFAGEQMMRLSMDLSTGTAGCLLALGSALHDTPVHLPFLPPPRRPQSRPSLQR
                     TEAQPRPHQAKGTSS"
     misc_feature    complement(11381..11383)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12690..12702
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.37"
                     /tool="antismash"
     misc_feature    complement(12955..12966)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            13161..13691
                     /locus_tag="C8250_RS00400"
                     /old_locus_tag="C8250_000400"
     CDS             13161..13691
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000400"
                     /product="hypothetical protein"
                     /protein_id="WP_138358106.1"
                     /transl_table=11
                     /translation="MTDAHESVGLFTIAGTQHGPYPGAVSGETSPYDSIAFDRAIVDQL
                     VDDVNRDISLFRAAWEGPVLRFSWTTAADGVASAHIRPDPHGRYRIGGLWPWADWDDWD
                     DESAPCSHKHAFALGVIEFCLTHTTPMPDHLLEPYNRGREAAHHVTLYQYAYRPDAPRP
                     APGRTACRPGPEG"
     misc_feature    13832..13852
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            14334..14618
                     /locus_tag="C8250_RS00405"
                     /old_locus_tag="C8250_000405"
     CDS             14334..14618
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000405"
                     /product="hypothetical protein"
                     /protein_id="WP_138358104.1"
                     /transl_table=11
                     /translation="MSLFRRSKSTPTTAAEHLRRQLANAADWSITIARRRTTPGQPTRV
                     TVDDVLARAAHDFNLLTVPPQAAAALRDRLHVRGTDNITTDAYHYDPTP"
     gene            complement(14918..15712)
                     /locus_tag="C8250_RS00410"
                     /old_locus_tag="C8250_000410"
     CDS             complement(14918..15712)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382057.1"
                     /locus_tag="C8250_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000410"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_138358102.1"
                     /transl_table=11
                     /translation="MDVPSLHNQFLSDALPRIRQDARVAGVAITGSIVGGRSDIYSDVD
                     LILVIDEEAYDVVMRERFALIGSWASLVAGFTGEHVGEPRVIITLVGPPILHVDFKFVR
                     ACDFAERTEDPEILWDRDGLLAGALAQQPPVTPAFDLQWIEDRFWIWVHYGATKLGRGE
                     LFETISFLTYLRETVLGPLAARRVGAIPRGVRHLESSAPEEARNLQATLCGYDRHEAGR
                     ALLATVDLYRRWSDAGEAIVERRHHAEKLAMQYLHDVIDQGC"
     misc_feature    15860..15872
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     misc_feature    complement(15965..15977)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            complement(15972..16109)
                     /locus_tag="C8250_RS00415"
                     /old_locus_tag="C8250_000415"
     CDS             complement(15972..16109)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000415"
                     /product="hypothetical protein"
                     /protein_id="WP_187144660.1"
                     /transl_table=11
                     /translation="MDWYTDITVPPQDGTYCGPCRHGQAFPNRGLRGALRRMRKASSDV
                     "
     gene            16468..16959
                     /locus_tag="C8250_RS00420"
                     /old_locus_tag="C8250_000420"
     CDS             16468..16959
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012859.4"
                     /locus_tag="C8250_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000420"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_187144661.1"
                     /transl_table=11
                     /translation="MASLLTIVLALCGLSALSAAPASASVNSWGVVSNDWSVITDCMTP
                     QGNGTSNGTKITTWDCTGSNLQQWGWDRNHLVHKVSGKCLTPSGNGSGTNGAVLTLWTC
                     DYSYGSPQEFSSTTRHTFTLFGGKCITNYGGNMAEGTVLTLWSCAPDLPREQNWTGYYI
                     "
     gene            complement(17449..17745)
                     /locus_tag="C8250_RS00425"
                     /old_locus_tag="C8250_000425"
     CDS             complement(17449..17745)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000425"
                     /product="hypothetical protein"
                     /protein_id="WP_138358098.1"
                     /transl_table=11
                     /translation="MPYDAFVMFAGVQGSYLSQPHPRGVCDDDQCPRFGAPPGGALMDF
                     SMVERRRGCRNLTGPERDLALRLAARADRLRTDAGREGGEDMGVAEAFALAAV"
     misc_feature    complement(18322..18332)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            18556..18921
                     /locus_tag="C8250_RS00430"
                     /old_locus_tag="C8250_000430"
     CDS             18556..18921
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000430"
                     /product="hypothetical protein"
                     /protein_id="WP_138358096.1"
                     /transl_table=11
                     /translation="MKKVLARSAAAAVLSAAALVSLSGSAHAATPQAAPASVALASDGH
                     HHGGHGQSHEGRHWDDDNQCDENGNEHSDDKGGHNYGGRSNGYHSGYDTGFDNYQGGYN
                     NGYYGGGLLGGLLGGIL"
     gene            complement(19022..19357)
                     /locus_tag="C8250_RS00435"
                     /old_locus_tag="C8250_000435"
     CDS             complement(19022..19357)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000435"
                     /product="hypothetical protein"
                     /protein_id="WP_138358094.1"
                     /transl_table=11
                     /translation="MATGEPVLFCGIWLTIRLLGILLGALGTGRVAPHDCTLLPRVLFW
                     TGCASCLLALTLPVLAAQPHLEARGGRAVVAYERIWQQAPRYCPGAGCPLAWILHQARY
                     PSTTAQA"
     gene            complement(<19745..20035)
                     /locus_tag="C8250_RS00440"
                     /old_locus_tag="C8250_000440"
                     /pseudo=""
     CDS             complement(<19745..20035)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009332786.1"
                     /locus_tag="C8250_RS00440"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C8250_000440"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWEIAEPLIPPLKVWPQGGGTQDTPDETLFAAIVHVLVSGYAWRA
                     LPPCFGMSRSTAHRRFVMRSRAAVWSRLHERILHRPNDAGLLDLSRAVSDSA"
     gene            20137..21747
                     /locus_tag="C8250_RS00445"
                     /old_locus_tag="C8250_000445"
     CDS             20137..21747
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000445"
                     /product="hypothetical protein"
                     /protein_id="WP_187144662.1"
                     /transl_table=11
                     /translation="MGPEVQVQQRAADLLVVRQVRAERTLLSQNRGSPRGPTDSSSERG
                     RPRACDAVSFGRISGQPVSQDHWKIRGVRIRLSGDLDCEGWGSRMDAGQGLLVLMGSGE
                     TSPTMVTLHRELVAHLEPGAEAVILETPYGFQVNREDISSRAREYFRRSVGLVTTVMAD
                     TDADVPAEVDSDTLHDQLHRAAWVFCGPGSPSYALRRWQEQGLGQALADRVRRGRGVTV
                     MASAAACTVGLVALPVYEVYKAGHPPVWLDGLDLLESLGLPVAVIPHYDNAEGGTHDTR
                     FCYLGETRLVALEKHLPGESAVLGIDEHTAVVIDLGAGSARVWGRGVMTVRRRGAVTVI
                     PSGTVVPLDRLRRLVAGTAATHSPGLWEATESVQPDAPSSVGGPVTLQEAVTAADTLFE
                     SARAARDAGGMVAAILQLEAEISSWSGDTEEDEGGQEWARTILRGMIRQLVAPAQQGMA
                     EPERTLGRVLDPLLDLRGALRAQGAYDLADRLRTSLAAGGVRIRDDARSSRWQLLPGDH
                     TAAIGADEPTGPAEDPPMT"
     misc_feature    20212..20214
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21758..22402
                     /locus_tag="C8250_RS00450"
                     /old_locus_tag="C8250_000450"
     CDS             21758..22402
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="C8250_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="C8250_000450"
                     /product="hypothetical protein"
                     /protein_id="WP_138358090.1"
                     /transl_table=11
                     /translation="MQLRRSGNRIGGGPLQHPGGSPTVLESTHGCLLAALRRRAPMMSR
                     TPGAASTPPVLVEALLLRYDAVTGFAYRRLLTALGRSSAPDRAARRLAGLPDDGDHHLV
                     HSTSWRADDEGAIVLTYVVHPDPDPDRPARPLADPHTIARSNRTGHPAPPDLTVDHVAS
                     HAVRHLALLESTDPVVAAFLAARPQAQDALSRVSALPAGQLRSAPTCSNPR"
     misc_feature    complement(22475..22490)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.44"
                     /tool="antismash"
ORIGIN
        1 ggtcttggct agcctggtgc tcggggcgga gccggtggat cactccgatc gagccaggca
       61 gacacggagg tcgtgtgctg ccctagggtc ggcggcgcag tgtggcgact gcggccgcct
      121 gtctcgaagc gccacggggg tccaggcaag gtgatcgtgc cgagagtgga atggtcgaca
      181 tcgatcagta gcccctgctg gcgggtctgc tcccaggcat agacctcggc cagggtgcgc
      241 acgcggccga caggcacgcc aactgcgtcg agacgctcga tccaggcgtc gacagtgtcg
      301 tgcgcaaaca cggcattaag ggctgtggcc aagtcggtac ggtgccgtac ccggtcggcg
      361 ttggtggtgt agcggggatc agctgggtcc aggcccgtga cggctgccat attgcgccac
      421 aaccggtcgc ttcccgctgc gagttgaagg tccccgtccg cgcagtggaa caggccgtac
      481 ggagcaatcg cggggtgctg attgccggtg gctgatggtt cctttcccgc gatggtccag
      541 cttgttcctt ggaagctgtg gaggcccacc actgcggaga gcagtgaggt gcgcactacc
      601 tggccgcgtt gggtggtgtg gcgttccagg agggcggcga gcaccgcggt cacgccgaag
      661 attccggcta gcaggtcagc gactggggtg cccaccttgg cgggggctcc gggctcgccg
      721 gtcaggctca tgagaccggc ttcgccttgg gcgatctggt cgtagcccgc acggccggcg
      781 tgcgggccgt catggccgaa tccactcacg gagagtacga ccagcgtggg gtatgtctcc
      841 cgcacctgct gcaacgggaa cccgaggcgc tccagaacgc cgggacggaa gttctcaacg
      901 agtacgtccg cctggcgcag cagccgcgtg agcagttccc tgccctgctc cgttttgagg
      961 tcagcggtga cggattcctt gttgcggttg caggaaagaa agtacgtcga ctctggtgtc
     1021 tgatccggac cgacgaaggg cggaccccaa ctgcgggcct catctccgtg accgggtgtc
     1081 tcgatcttga ttacccgtgc gccgagatca ccgagcatca tcgcagcgtg cgggccggcc
     1141 agagcgtggg acagttcgat caccaggcag ccgtcgagcg ggccgcttcc tgacgcttcg
     1201 gggtcgaaca tgctgaggtg gtccctttca tcgatcttcg cgttgacctg ggccaccgta
     1261 tgcaaacgga catcagagga atcgccggag agggttaaaa gcgtcttacc cgccgcgata
     1321 cgtttatcgc cttaactcgc gcggtcgagg gaccaacctt gctcgttccg gccctgaagg
     1381 gcaccctact aacgggctgg tccgtagcta tccagggcgt cccagcagca tctgagacgt
     1441 ttactgaccc ggacaggaag ggcgtccggc attgagcgcg tggatagttg gcccgatctc
     1501 tccagctctc tgctgtcctt cgccgagtcg cgctcctggc gcactgcaac cgccccgtgg
     1561 cctcacagcc gggtcgcatc cttttcgaca acacgccacc aaatcaatac cgttgagctg
     1621 gacacctatt tttccgacgc tcccgcctgt gctttctttt ccgggcgaaa ggtccgtcgg
     1681 ataggcgtac tctgcgtatc atcgctggtc aggacgagtg gaggagggcg aaatcgtgcg
     1741 tagggcgctc gcggagttgc taatcgtcga agacgacgct gagatcgcgt ccgagctcga
     1801 tcgtgccctg gtcggccacg ggtatcaggt agttcatgcc gctactggag ggcaggctgc
     1861 cgagcaggcc aggcgtcggc cgcccgactt ggttctgctg gacctcggac tgccggacgt
     1921 caatggggtg gaggtgtgcc gcagactgcg cgccttcctc ccggtagaaa cggtcatcgt
     1981 cgtcctcact gcacgcaccc tggagttcga agtagtggtc gctctcgacg ccggcgcgga
     2041 cgactatctc accaagccgt tccgtctgac cgaactgctc gcgcggctgc gcgcgcatct
     2101 acgccgccgg gctactgcgg ccggaccgcc ggtcatgcgg atcggcggca cccgtatcga
     2161 cacccagacc cgcagggtgc atatcggcga cagggaggtc cacctgcgcc cgaaggaatt
     2221 cgacctgctc gctaccctgg cggcgtcggc cggagcggtc gtgagtcgtg aacatctgat
     2281 ggctgaggtc tgggacgaac actggttcgg ccccaccaag accctggatg tgcacgtctc
     2341 ggccctgcga cgcaaacttg ccgacgccga cgagcgtggt ggagagtgca tcacgacggt
     2401 gcggggcaag gggtaccggt acgagacaga caagtcacca gtcagttgac cgtcgatcgc
     2461 ccaggcagtg actcgcaact ccccgcgtcc gtcgccggta acggttcgca cgccggaaga
     2521 agaaggctga acaccggccg gggtccgggc ctgcgcagta gcagtctgcc gccttcggct
     2581 tcggcgagag agcgggcgag cggcatcccg attccgtggc gctgaccgtc gcgccgtacc
     2641 gtgccgaaga ctgcgtcacc gtcaccggcg ggacccggtc cgtcgtcccc cacctccaaa
     2701 gccacgcctg cgcccacgtc cgtcgcactc agtctgactt caccccttcc gtggaccaga
     2761 gcgttgtcca tcaacgtgcc catgatctgt gccacagccg ctgccgaggc gctgaccggc
     2821 ggcagtccgg cttcgcaccg cacggtcagg cggcgtccag cctctccaat tgcgtcacgg
     2881 tggcgcctgg caatgtcgtt gagcagacct tcgacctcga cgatgtcggc ctggtggtgg
     2941 gtctcgcgcg ccagccgcag caggtcctcg atcgtgtcac caagatgttc ggctctgcgc
     3001 aacgcggtga ccagcgcccg cccccggccc tggtcgtcga gtgactgcgc tgtgtccaaa
     3061 cccaaaacga gcgccgtcaa cggcgtacgc aactgatggg agaccgccgt gctgaaccgg
     3121 cgctcacgct ccaagagagc tcccaaccgc cccgccgtag tagccagtgc ttgccatgcg
     3181 gcatccgcct cgcgtatgcc ggtgcactcc ggacggatac tgaagtcccc tgatcccaga
     3241 gcttgggcac tggccgtcag tcgctccagt ggggtggcaa cccgacccgc gacgcgccag
     3301 gcgagtaacg cggccaacgc gacgactacc gcaccgacag ccgccagcaa cagccaagcg
     3361 agcatggtgc tgtcggctac tggatcccag ggcatccatg cccgcaccac ctcgcgcacc
     3421 gtgccaccct ggacgaccgg agcgaacacc gcgagatttc cgccttcgac cccccgatgc
     3481 agtgacccgt cacgcgatga ggccgcccct ggggacaggg caggaccgct gccgtggacg
     3541 cgccgaccca gcgggctgta tacccctacg tgaacaccgt gcgagggagg atggagcgtg
     3601 accagacgat cgggggctcc accggtaccg cctgacaagc tcgccgccgc ccagatggcg
     3661 tcgcgttcca ggcatgccac cgccccgtca cggtagatcc ggtcgaccgc gatggccaac
     3721 ggcacagtga acaccaggac agcgcacgcg gtgacggcga cgatcgaaac catcactctg
     3781 ccgcggacag atgacccgac gaatccccta ccgaggatga cgtggccgtc cacactgctc
     3841 atcggcgtgg taccagaata atcgtcctag ccggtgcacc cccgtcagtg ccccctcccc
     3901 caacacaggc attcaactgg ccgtaggagc cacggtcagg tttgggagcg gcgtcggcct
     3961 cggcgtcgtc agagaagggc aattcgagca tggcgtctca acgagcggtg ccatgccatc
     4021 gttacccgcc gcccagcagg agccccgcca gcgccacccg atgcccgcct cggtgccccg
     4081 gtcccgcacc gctcgggcgg ctccaggcca gcagtatcag ccctgccgag cagagcacca
     4141 ggacagcgga ccccaggccc ggccagaagc gcggccagac accagccacc acggcactcc
     4201 acaccgcggt gccgccgatc atcgtgggca gcatccacgc gcgggagccg cccgcaaggt
     4261 gggcgcgcca gcactgagcc gtgccgatcc ccgtcaaggc cgcgagcggg gccgccacga
     4321 cacccatgta gtacgtgtgc cccgcgaccg tccccgcgct gaagacggcg aggaacgtcg
     4381 tcagccagcc accccagagg agcagggcgg cccgctcggg gtcgctgcgc ggccggcgcc
     4441 gcagccacac caggccgcag cccagcgtca gggccgctgc cggatacagc cagccggtct
     4501 gcgaggccag gggcgcgcga accatcttgg tccagccacc ctcgtcgccc gtggcggcgg
     4561 ccgtcccggc tccgcctcct accgaccgct ttgccacagg gccgctgggt acggagttga
     4621 cgctgccggt gtcggccggg gacagcccca gctgagggaa gcggtttctg cggcgcagcg
     4681 tcatgggagc cacgaccaag aagagggcgg ccaggacggg cccgagggcc cacgcttcca
     4741 gcatcttcgc ctggaaagcg agccccaccc agacggcgct ccagatgagc gggcgctgac
     4801 gcgccgtgct ggatgcccgg aacgccgcat cggcggcaag cagcaggaac agcgtgaacg
     4861 gtgcgtcctc gacagtcgag cggaacagtc cggtcgccgc cggagtgctc gcgaacgccg
     4921 ccgcggccac caacgccgca tgagctccgg cctgcctgcg caccagcctg aacagcacca
     4981 acacactcag cgcgccctcg atcacctggg acaacgccag cgcccaggga tgaaaaccga
     5041 acagccgcgc ggagaccgcc tgcggccaca agaacccggg cagtttgtcc aaagtgatgg
     5101 agttgccggg ctcgaagaaa ccgaagaaga acgccttccc cgtttctgct catgctgagc
     5161 acggtgtcgg cgtagaacgg atgaaactga ccacggtcga tgttccaccc gtacaccgcg
     5221 gtagcgatgg ccgtgatcac caacagcaag ggacgcacgt acgcaggctg cgcggccggc
     5281 gaacaccaaa agcggtgccg gatacggcta ctggtgcagg tctcgaaacg ggacgcctgg
     5341 gtggccacat gcgaagtcat aaggacgatc ttcagacgaa agcgcccact gcgtggtccg
     5401 tttacgacat ctcgccgtcg gccagccagt cgatttggct ctgcagagcc gcggaacatg
     5461 gatcacaggc gcgcttgaca cgttccccag cagggcgccc catgtgtgcg ctggtgcatc
     5521 gtttggccgg tagtggggtc catcgtcatc ggctgccggg gtacaagggg tcgtacgagg
     5581 cggcgagcgg ttccggaggc tggaagggtc ggcgccggga gtcagggacg aaatgaggcg
     5641 aacgtgatcc gggttctttg ggtgcacgac tcacagctga tgcgctcggc gctggccgcg
     5701 ctgctggacg atgagcgcga catgcaggcg gtcacctcct gctggaagaa cgcgacggcg
     5761 cgggccaaag cgttgcgtcc gcaggtctgt gtggtcgacg gggactgtcc tggttccagc
     5821 cggttaccga cccggcccgc ccagcgggac tgtgcgctgg tggtgctgac ccgccagttc
     5881 cggccggggg tgatgcgttg ggcgacggag gccagggcgc tggggttcgt ggacaaggac
     5941 gctcccccgt cgaccctcct gagcgccata cggcaagtgg cggcgggtga gagatatgtg
     6001 gataggtcgc tggccttcga tgtgctgcag gcagccgcga taccgctgtc gccacgggag
     6061 ttacgggtcc tggccctcgc cgccggcggc gcctcggttc cggagatcgc cgagagcctg
     6121 cgcctgcggg aaggaacggt ggggaactac atgagcgcca tcatccgtaa gaccggcggc
     6181 cgaaaccggg tggacgccat ccggatctcg caggaggccg gctgggtgtg accggtcggc
     6241 tcgatggtgc tcacaggtgg ctggcgtgcc agcgtccgac gaggtcctgg tagagcgccg
     6301 acgccgcgag cagctcttgg tggctgccct gggtggcgtg gattccgtcg agtaggagga
     6361 tccggtccgc tcgccgggcc gagctgatgc ggtgggcgac cacgatcagc gtgccgaacc
     6421 gctgggcgaa ggctccttcg acctgcgctt ctgcggccgg gtccaggtgg caggtggctt
     6481 cgtcgagcag gacgagcggc gcgggcgaca ggtgggcacg gcccagggcg atcagttgcc
     6541 gctcgccttg cgacagggac gccgggtcga gcggtgcgtc aaggccgccg atccgtcgtg
     6601 ccagggggcc gagtccgacg gcttgcacgg aggcccggac ggcttcggcg ggtgcgccgc
     6661 gggcacatag gtagagcagg ttctcgcgca gcgtgccggt gaagacgtag gcctgctgtg
     6721 ggatcaggac gcgccgcagc gatggatctt ccccggtggc caggctggct tcgcagccgc
     6781 ccaccgtgat ccggccgcgg tctggtgtca ggactccggc gatcagtgcg gtcagggtgg
     6841 acttgccgat gccgctaggg cccacgaccg cccagtgttc gcccgcttca atcgtcagat
     6901 ggaggtcgca cagcaccggg gccgcctcgg ggccgtaggc gaaggtcagc ccggtgacct
     6961 cgaccttccc gacgggccgc tcttgcccac cagcagcagg tgccaccgat cggccgacga
     7021 tggaggcgtg gcccggtggg gtgtcgtcgg tgagccggcg caggacgacc aggagcctgg
     7081 tgccggccgc gccgagggcg ttcatcagtg tgtggagggc gggcaggagc gcctgcgtca
     7141 ggtaggtgag ggcgcccaac agagagccgg tgctcaggcc gcggtccagc agccaagggg
     7201 cgcagagcag cagcaggccg atcggcaact gtccggcgat gcctagagcc agggttcgta
     7261 cggcggccca gcgggccagg gagcgcgccg cgtcggcctc ggcgtcgatc atgcggtggg
     7321 tgtcaccggc gacggcgccc tgggagccgc aggccaccac gtcacgtacc ccgctggcga
     7381 tggtcccgaa tcgcgcggac agcgcctcgt cggcccgcag gaacgcctct tggcgggcgg
     7441 ccatgggtgc gagcgtcgcg aggaacagcg cgagccctgc gaccaggggc gggagcacga
     7501 tcagcagcag ttgcgtgtcc agtgaggcga gcccgaccag cgcgccgacg gcggtgaaga
     7561 cgaacgaccg tgcgacgagg accagtccgg cgaaactgtc gcgggccatc tccgtctgat
     7621 tggtcagctg ggagacggcg gcgctgtccg cggcgcgacc gctgtcgtcg agcgaccggg
     7681 tcaccgcccg ggtgacgacg gagcgtacga ggccgtcgcg gagcggttcg acgaggtcgg
     7741 cgaggccccg gaaaacctgc cgggtggcta gaccgctgac gacgatggcg cctgcggcgg
     7801 cggcgagcca ccacagtccg gtatcggtac ggccggcgag gaaaccgttg tccagggctc
     7861 tggcgacacc gtagccgcta aggaaggtct gcgccgactc caggagcgac cagccggcca
     7921 acaacagcag gacccgggcg cgagcccgca ggaaggacca ggctcgcgag cgtacggacg
     7981 tgcgcgagcc ggtcatgggc cgggctcgtc gtcgtgctca ggatccgcaa acacggcccg
     8041 gtagccgggt tcccgccaca gctgctgatg ggtgccgacg gcgcggaccc ggccgctctc
     8101 gatccacgcg acctggtctg cccgcgcggc ggacgagaca cggtgggcga tcagcaggcg
     8161 ggtgccgggc atcacctcgt gtgccagcgc ccggccgacg tgcaactccg tgacactgtc
     8221 caggctggat gtcgcatcgt cgaggatcag cagccggccc gcgtgcgcga acgcccttgc
     8281 caggccgagg cgttgcagtt cgccgcccga cagcggcgcg tcctggatcc ggcaggcgta
     8341 ccggcccggc agccgcccga tgaactggtc ggcgtcagcg gcgcgggcgg ccgcctcgat
     8401 ctgccgtccg gtgggcgtgt aggggccgaa cgcgagggcg gcgccgatgg tgtcgccgaa
     8461 cagcgtcggc cgttcgaagg cgtacccgat ctcgcggcgc agctgggcgg gatcggtctc
     8521 ctccagcggc actccgtcca gcaggacctg gccgttgtcc ggatcggcca gccgtccggc
     8581 gatcgcggcc agcgtggact tgccggctcc cgagcggccc acgactgcca tggtcgtgcc
     8641 gccgggcact gtcagatcga ctgagcgcag gaccgggaca ccggcccggt ggacggtgac
     8701 tgcgcgcagt tccagggttc cgggtccgtc ggcgggcagt gcccggtggc cgccccgcat
     8761 cgctggcacc tcgaggatcg cgagcgtgcg ggcggccgct gcgcggctgc ggatgagggt
     8821 gttcagctgc ccgaggacgc cgcccaggcc ggcggcgagt gcggcgtagc gggtggcggc
     8881 cagtagttgg ccgacggaga ggtgtcccgc tgccagtcgc agtccgccga gggcgaggac
     8941 cgcggtgatc agcaggggga cgaggatgct gctggaggcg actgcgcgtc cgtagacctg
     9001 ccacatgcgt ctgccttgtg tgttcagttc gctcaggggc gccaggatgc gggcgcgctc
     9061 gcgccgctcg gtgccggcgg cggcgactgt gcgggcaccc gccagagttt cgacgagtcg
     9121 gttggcgagc tccgcctgta ccgcctggta gcgggtgacg ctgtcggagg aggtccgggt
     9181 gaaggcgcgc agcagcagag caaaaaccgg cagtccggct gcgtagacga cagcgagcgg
     9241 ccagtcggtg agggccagcg cgagcagtcc gccgatcggc gtgaggagtg cggcaagtcc
     9301 agtggcggcg gtcaccggtg cggcacccgc ctcggcggcg ttgccggtca agcgggccac
     9361 caggtctccc ggggggaacc gttcggcggc ctggtgcggg gcgagggaga gcagtcggtc
     9421 ggtaccgcgg cggcgtagcc acgcggtgct gcgggccgtc atgacaccgc cggacagggc
     9481 gacgacgctg tcgaggagca cttcggcggc gatcagcgcc aggcacagcg cgatcgaccg
     9541 gccggcgccc gctgcgtgcg ccaggatcag gtcgagggtg cggcccagga ccgcgggcag
     9601 cgccaccgcg gcggcggccg aagcggtact gcaggccagc acggtcaccg cgtgccgggc
     9661 actgtggcgc agtgccccgg tcagggcggg tccgggaccg gccgtgcccg ccggcgcagt
     9721 ggttgccgag gctggtacgg gggtggtccg tggggatgcc atggcgtggt ggtccccttc
     9781 gtcgctgggt cgctacgtcg gtgtggcgtc ccgggcgatg ctccgcccgg gacgccgctg
     9841 ccgcgtcaca tcgcggctgg tgacctgtga ggtcagttgc aggtggtgac gctcaggctg
     9901 ctgttgccgc agagcagcag gctcgcgcgg ctgccgccgg tggcgagctc gcccatgtcc
     9961 tcggcggccg gggtttccag ggtctgcagg tcaaggagtg tcatgatgat gttcctttcg
    10021 cttggtgggg acggggttgt gcttcggtcc tctgaaggga gggccggctc tggggccgcc
    10081 gtggtggcgg gaggaagggc aggtgcacgg gagtgtcgtg cagggcgctg cctagtgcga
    10141 ggagacagcc ggcggtgccg gtgctcaagt ccatggagag gcgcatcatc tgctcgccgg
    10201 cgaaggccag atgtccttgg taagggacgg cgccccaggc cagggagtcg atctggcggc
    10261 ggaggtccgc actgtgggtg ccgggtccgc cggtggtggt gcgcgccagg tgcaggacca
    10321 tgccggccgc tccgcggaac agtccgggct gggcgtagaa cttggcctgc gcggcctgca
    10381 cgatctcgcc gcgcgcctgg tcgaaccgcg tgtcgtagcg gtgcgggagg tagtcgtcca
    10441 ggaccatccc gatgcccacg ctgcccgcgc cgaggtatgg catggtgcgc cgtccctcat
    10501 cgacctggag ggtgccgccc accgcacgca cgcagcgcgc caggtcatgg cggagcgcct
    10561 cggcggccag gtcgagtaga ccgccgtcac cggaccgctc gtacaagcgc aggtacatca
    10621 gcgctgtgcc ggtggcgccg tgtaggagcc cggcgcgtac cgtggggcgc ccgccggcgg
    10681 cctggggcgt ggtgtccgct gccaactggg cgcagcgcag ggcgtggtcg cgcagagcgc
    10741 cctcccccgt gctggcggcc aatgagtcca gggccagccc gatacccgcc aggccgccgt
    10801 gcagatcggg gctgatgccg tcccagttct gcgaagtgat caggtcggcg agatcgaggg
    10861 cgcgttcgcg gtgtcccagg cgttccagga cccaggcgac gcccgccagg ccgttgtaga
    10921 agcccagcgg cgtgccggag gctggtgact tggtggtgcg cagcagccat tcctcggcga
    10981 cgggtgaggg tgcggcgcct gtctcggcga gggcgtgcag gacaccggcc gccccgtagg
    11041 cgaagcaggc gccgccaccg ggaacggaga actgcgcgat gtcgccgggg aagatccggt
    11101 cctcgcggtc cggggtcgct gaggcggcga tggccgccgc catggagtct cgggacgcag
    11161 gccagtcacc cagggcgacc gggagatagc tggcctcagc gctcgccgcc cctccgctgc
    11221 gcggatgcgg ggcgctgtgg ccacgcacga tctcctcgac cgcttcgtcg aggaatgcgc
    11281 gcggtacggg aaactgctcg gcggcgatct ccgccaagtg gcgtgctttg gcgcggtcga
    11341 ccgcgaacag gctggtgagc ggcaggaaca gtgcgaggcg taagcaggcc agtgcgtagg
    11401 tgtcgaccgt aaaaccgcgc cggtcagcag gggccacgaa tccggggttg gccaccacct
    11461 ggcgactgtt gacgtcgtcg acggaggcgg cttcgaagtc gagcagcacc acggacgact
    11521 cgtcctcgga catcatgatg ttgaacaggt gcaggtcgtt gaagaccaca ccacgcgagt
    11581 ggatggctgc caccgcctgc tccaccagcc cgtagacccg ccgagcccac gcggtgtact
    11641 cggccaggct ctccgggctg ggatccggct cgatcagcgg gtgtcggtgg gcgaagaaac
    11701 tgttgagcgg gcgtccctcg atgaactcca gggccaggaa ttggtgatcc ccgacagtga
    11761 accagtcatg gacctccggt gtacacccca gcccggtcag ccgcagcagc gcgtcgcgct
    11821 cgcgctccaa ccgggtgacg gcgtccgcct cgtcggcggc cagcccggcg tgcgggcggg
    11881 cctccttaag gacgacccgt gcgtcggtgc gcaagtccgt cccgacgtac accccgccgc
    11941 cgttggagaa gtgcagggca cgctcgaacc ggtagggcag gtcggtcacg gtagccgcgg
    12001 cgcgggcctc caaatggggc cgcaggaact tcgggagagt gacccactgc ggtacgtgaa
    12061 aggtgggatc cctacgatcg ggaaccaagc ggccctggtc gtcctcaatg gcgggacacg
    12121 accggccctg gtcgtcgtag cagttacgtt cggtgaagct gccgtagcgc acgtacaccg
    12181 ggccggcccc gacgcgcagg tcggtgagga tgtacggacc cggctcagcg cccagcagcg
    12241 tgttgagatc ctccgcggcg gtgcggaact gctcgtcgtc cgtggggtaa atcgtgatga
    12301 acttcccgct gccgctccgg tcaccgtact tggcgttccg ggtgtgcagg aggtacctgc
    12361 tcggcatgca cttgaacgcg atggagcggg ggacgcagta gtcccagaca cgggaaagaa
    12421 tggactcggc gttgtccaga caagccgata cgtggatctt ccacccctgg aagggcaaat
    12481 tcgtctcgac gggccggaac gccagccagt cccccgagcg gtgctgctgc cagccgtcgg
    12541 gcaactcgcg tcccagcggc gggtacatcg cgcctcggcc ccggccgtcg gcggacagcc
    12601 ggtagggagc gtcgtagaac tgacggtctg cgtcgcagaa aaccgcgtac ccctcgttca
    12661 tcgcgctccc tcgcccggcg gttgaggcct tgacggtgtc acggggtcca ggggcggaac
    12721 agtcgtcaat gtaatgaaag gcccgtgaag aatgcacgga tgaaaatcga cctgctggtc
    12781 gtgacggctc ccgacccgag ggaagcagcg gtgctcacgg ggaccgccca gggcggccgg
    12841 tcacggacct ccggctgcag cgcagccgcg cccgcccatg acgattgcgt tcatctgctg
    12901 gaaacgggcc gacgcagaag ccatgagcgg caggggctac gacgcgttcc gcaggcgttc
    12961 atgtcgacac atgtggggca acaaaccggt cgccctgtgc cctgcacaga cgttcagcgg
    13021 gaatcaccga ccttcaagga cccgccctag gggagcgtca cggagtagac tcatgcgtac
    13081 tcaacgttgt tcgcgtgctc gaacagcggt caaatgggca tgacgtcacc agaagcgtcc
    13141 atcagtgccc gaggagtgac gtgacagacg cccacgaatc cgtcggtttg ttcaccatcg
    13201 cggggacgca gcacggcccc tacccgggtg ccgtctccgg agagaccagc ccctacgatt
    13261 ccatcgcctt cgatcgcgcg atcgtcgatc agctggtgga tgacgtcaac cgagacatca
    13321 gcctatttcg tgccgcttgg gaaggtccgg tcctccggtt cagctggacg accgctgcgg
    13381 acggcgtcgc cagcgcacac attaggcccg acccgcacgg ccgctaccgc atcggcgggc
    13441 tgtggccgtg ggccgactgg gacgactggg acgacgagtc ggcaccctgc tcacacaagc
    13501 acgcattcgc cctgggcgtc atcgaattct gcctcaccca caccaccccc atgcccgacc
    13561 acctcctcga gccgtacaac cggggccgcg aggcggcaca ccacgtcacg ctctaccagt
    13621 acgcataccg accagacgca ccacggccag cgccaggccg aacggcatgc cgtccaggcc
    13681 cagagggctg acagccaacc gagagcaagc cggactggtg aaccaggtgt tggccacctg
    13741 ctggcacacc accgccgagg cgatcgggaa attgcgggac tggcgcgacc agggacatgc
    13801 tgccgactaa acccttcctc taccccgccg aagacgcagc cctggccaag tgagaagagc
    13861 gggcagcaca ggtgacaccc gccgggaaca tctggcgtgc agcagtgcag cacgccatcg
    13921 ttgcagcgcc ggtcagacct gtgccggcga agtggcgcca ggcaggtggc cggtcacgcc
    13981 cttggtaggt gtgagggcgc ccgcggttcc cggccgacgg gccggcggcg aggcgcggaa
    14041 aggttcgcgg cccatgagcc gctgtgatca tgcctaccgg tgtgccgata cgatccatca
    14101 caggatcact actccctgag gtagtcaggt ggagcggtgc tctcaggccc cggactggtg
    14161 ctgatacacc ggtgcggggg ctgccccatc gcctggacgc actcgcacag gagatgcggt
    14221 gacggcaacg cccggcgccg ccgtcaccgc gcgggagtac gaggcgtgcg ccacgaaaag
    14281 cacccgcgca ccaccacacc cgcaaccatc cgccccaccg aagtggacta gcgatgagcc
    14341 tcttccgccg ctccaaaagc acgcccacca ccgccgccga gcacctccgc cgacaactgg
    14401 cgaacgccgc cgactggtcg atcaccatcg cccgccgccg aaccacaccc ggccaaccca
    14461 cccgcgtcac ggtcgacgac gtactcgccc gcgccgccca cgacttcaac ctcctgaccg
    14521 tcccgcccca ggccgccgcc gcactccgcg accgcctaca cgtacgcggc accgacaaca
    14581 tcaccaccga cgcctaccac tacgacccca caccgtagga acggcaccac acggcctcta
    14641 cgacgtcacc ctcacggact gcccgcccac ccgccgcgca gaccattccg gctccgactg
    14701 cggttgccct tctcaaaagg gcgcagcccc agtaacagtc cgcgaccacc ccgactctcg
    14761 atctgcgctc cctagccgtt cgtgaaccgc agcggataga gcagccggga cggccgggac
    14821 aggatgatgt gcggcatgag cgaggcaggc accatcaccg tcactgcccg cgtcaatctg
    14881 ggccgacaag gtggtgaggt acttcagccc gcttcagtca gcagccttga tcgatgacgt
    14941 cgtggaggta ctgcatggcg agcttctcgg cgtggtggcg ccgttcaacg atcgcttcac
    15001 cggcgtcgga ccatcggcgg taaagatcga cggtggcgag gagcgcccgt ccggcttcgt
    15061 ggcggtcgta gccgcacagc gttgcctgaa ggttgcgcgc ctcttcgggc gcgctggact
    15121 ccaaatggcg tacaccgcgg gggatcgcgc ccacccggcg ggcggccagg gggccgagta
    15181 cggtctcgcg caggtaggtg aggaagctga tggtctcgaa cagctccccg cggccgagct
    15241 tcgtcgcacc gtagtgcacc cagatccaga accggtcctc gatccattgg aggtcgaacg
    15301 ccggagtgac tggcggctgc tgggcaagag cgccggccag caggccgtcc cggtcccaca
    15361 ggatctccgg gtcctcggtc cgctcggcga agtcgcaggc ccggacgaac ttgaagtcga
    15421 cgtgcaggat aggcggcccg acgagcgtga tgatcacgcg cggctcgccg acatgctccc
    15481 cggtaaatcc ggccaccaag gaggcccaag agccgatcag cgcgaaccgc tcccgcatga
    15541 ccacgtcgta cgcctcttca tcgatgacca ggatcaggtc cacgtccgag tagatatcgg
    15601 agcggcctcc cacgatggac ccggtgatcg ccacgccagc cacgcgcgca tcctgccgga
    15661 tccgaggaag cgcgtcgctg agaaactggt tgtgcaagga ggggacgtcc atttgctttc
    15721 cttccgctcg gagcaaagca gatgaactta acactcagcc aagcgggatt cgcaacccga
    15781 atttctcaca aacgaaacga tccgttgcgc gagcaagatc gacaaccggc cgccgaaccc
    15841 cgcccgaccc tcgatcagtg tcacgctgtc acccccgccc ccgctgcaaa gggggagttg
    15901 aggggtatcc gccaaggtca gagacgtgtc agcggttagc gggccaccgg ccgtgacacc
    15961 cgccgtgaca gctacacatc actcgacgcc ttccgcatcc ggcgcagcgc cccacgcagc
    16021 ccgcggttcg ggaaggcttg gccgtggcgg cagggcccgc agtaggtgcc gtcctggggt
    16081 gggacggtga tgtcggtgta ccagtccacc ggcgcatcaa ccagctgctc gcagcccggt
    16141 gtcgcgcact gcggaacaac cggtgcgctc ccttcctcct cttcggcctg ccactgctgc
    16201 agttgctgcg cctgtccagc cctacccaga gctgacccca gagaaactgg ccaccacccg
    16261 ccccaacagc tcttctaaag atcttgtaat gtctgcagag cgacaggtag tttgtcgcat
    16321 ctcacctcgc atgtaggtgg cacgagtccc gtgcagccaa gacacgcagc agagcagacc
    16381 attcccgtac cggtgccgct ggccgcgcgt cacatccgct gcctgcgctg tgccggtttc
    16441 tcatgagcaa ggaacagcat gcgcaagatg gcttcgcttt tgaccatagt cctcgcccta
    16501 tgcggtcttt ccgccctttc cgccgctccg gccagcgcct ccgtgaacag ctggggcgtc
    16561 gtttccaacg actggtcagt catcaccgac tgcatgaccc cgcagggcaa cgggacatcc
    16621 aacggcacca agatcaccac ctgggactgt accggcagca acctgcagca gtggggctgg
    16681 gaccgcaacc acctggtgca caaggtcagc ggcaagtgcc tgaccccctc gggcaatgga
    16741 agcggcacca acggcgccgt cctgaccctg tggacgtgcg actactccta cggatccccg
    16801 caggagttct cctccaccac gagacacacc ttcaccctct tcggcggcaa gtgcatcacc
    16861 aactacggcg gaaacatggc cgagggaacg gtgctcaccc tgtggtcctg cgccccggat
    16921 ctgccccgcg agcagaactg gacgggctat tacatctaac gtcccgccac acactcgtcg
    16981 ccgggtggac cttacacagg tccacccgga tcgactccac ggcaaaggtg ccaccgccgg
    17041 gagcctcatc cgatccaggg cccagcttca cctggacaga tacggcgaca tgccctgcca
    17101 tacggctcgt tcatgcggtt gtgacgacac ccagcccttc aagtggcccc cgtaccccag
    17161 gccgccgccg cactccgtgc cgcctacacg tacgcggcac ggacaacatc accaccgacg
    17221 cctaccacta cgaccccaca cggcaggaag ggcaccacac ggcctctacg acgtcaccct
    17281 cacgggctgc ccgccccctc acgggtagcc ggactcctgg cccccggtgg tgaggaagac
    17341 agcccagcgt aggcatcggg ccgcccttcc cgcacccggg cagactgctc ggccgcctgg
    17401 cggacatcct cagccggcgg ggctgcctac ggatggttac aggcctagct agaccgccgc
    17461 cagagcgaac gcctccgcga cgcccatgtc ttccccgccc tcccggccgg catcggtacg
    17521 caaccggtcc gcgcgcgccg ccaagcgcag cgcgagatcc cgctcggggc cggtcaggtt
    17581 ccggcaaccg cgccgccgct ccaccatcga aaagtccatc agcgcaccac ccggcggggc
    17641 cccaaaccgc gggcactgat cgtcgtcaca cactccgcgc ggatgcggct gagacaggta
    17701 cgagccctgc accccggcga acatcacgaa ggcgtcgtac ggcatacctg tgaaggtgtc
    17761 atctggcaca gccgccacgg tgaagacgtc gcccggcaca actctgtcat cgctcgcact
    17821 catacccagc ccaacgaccc acccgcgcgc ccggcacggg cgccctccca cgcgcgagcc
    17881 accagcccct gccacgccga cctcaccgcc gaccaccgcc tcccgccctc ccatggccgc
    17941 caacccctgc ctaccggcgg ccacgggaag cacccgcggt aaaggcggtg tcggcgacgt
    18001 aggtgatgcc ggtagcggca ttgacggagg cttgggcggc caggaccgcg tgtccaccga
    18061 cggcggcacc gaccaatggc ggcaccagcg gcgcgggaca caccactgtc ccctgctgaa
    18121 caccacagcc gaacacgctg gtgaagggaa acccgcaggt accagagggc ccaggagcca
    18181 gcacctcctg cggagggtcc gtcgggggtc gggtcgactg tatgcatcgg ggtgtcggcc
    18241 gggcgaccgg ggcagcacgg tgcacgatga gtgcaaggtg gtcgcgcgca cgcatgacca
    18301 ccttcctccc gcccggtgcc cgtgacatgg ctgctccggc ccacggcacc gggaacgcgg
    18361 ccgtcgccgg ccgcacgcag gcgcgcccga cacgcttcgg ctaggagaca gtcgggcgcg
    18421 tcctgctgat atccggcgac cacggctcct gtgcggcctg cccttgcatc cgatggccca
    18481 ttccgccgcg ccggatcacc ccctcccctt tagcgtccaa gatgacccac tcaccccgct
    18541 tttgggagtt tgatcgtgaa gaaagtactt gctcgcagcg ccgctgccgc cgtcctgtcc
    18601 gctgccgccc tggtctccct cagcgggtcg gcccacgccg cgaccccgca ggcggcgccg
    18661 gcctccgtgg ccctggcgtc cgacggacac caccacggcg gacacggcca gagccacgag
    18721 ggccggcact gggacgacga caaccagtgc gacgagaacg gcaacgagca cagcgacgac
    18781 aagggcggcc acaactacgg cggccgcagc aacggctacc acagcgggta cgacaccggc
    18841 ttcgacaact accagggcgg ctacaacaac ggctactacg gtggcggcct gctcggcggg
    18901 ctcctggggg gcatcctcta accacccctc accacggtgt gtttcccgcc ggccacccac
    18961 ggcgggaaac acaccgcgcg ctactgccca ccctcgggct gccaaaaaac aacccgcggt
    19021 atcaggcctg tgccgtagtg gaggggtagc gggcctggtg caggatccag gccagcgggc
    19081 agccggcacc agggcagtag cggggggctt gctgccagat ccgctcataa gcgaccacag
    19141 cccggccgcc acgcgcctca aggtgcggct gcgccgccag caccggcaag gtcagagcca
    19201 agagacagga cgcgcagccg gtccagaaga gcacccgcgg cagcagcgtg cagtcgtgcg
    19261 gcgccacccg tccggtgccg agtgcaccca ggaggatgcc gagaagacga atagtcagcc
    19321 atattccgca gaacagaaca ggctcaccgg tggccatgtc gttgagcgct gcatgcggct
    19381 ccagtacgcc cggcgacttc tgccgtgccc gctccttcgc cagtcgctgc ttgatcgccg
    19441 cggcgcggga ctcttcgtaa ctcccgcgga aggcggggcg tcggtctcaa gttggacaat
    19501 acggctgttc taccagccac ccgcgcctcc tcctcggtgg cgatcgagtg cgtcgcccaa
    19561 aaaccgtttg cctggggccg cagtcgacga aattctgagg ttcgctccag cagtccactg
    19621 gcggcgtcgg gaatccactg gcggcactcg acacgtacct gagcttcgag gcgctaccag
    19681 ttgagcctgg ctgacgcgtc cttgcagagt gagggcgtcc gcgcgccggg tcttcagctc
    19741 gctgagcgga gtcggagacc gcgcgtgaga ggtcgagcag gccagcgtca ttggggcggt
    19801 gcaggatcct ctcgtggagc cggctccaca ctgcggcccg tgaccgcatc acgaatcggc
    19861 ggtgagccgt cgacctcgac atcccgaaac aaggtggcaa cgcccgccag gcgtatccgc
    19921 tgaccagcac gtggacgatt gcggcgaaca gcgtctcatc aggcgtgtcc tgcgtcccgc
    19981 cgccctgcgg ccacaccttc aacggcggga tcagcggctc ggcgatctcc cacaacccgc
    20041 cggtgtccta tcgggcgttc ggacgttgct ccgggaaacg cggcccggcg cccggagcca
    20101 gcgcgatgga cccactgcat tgtcgtccga cgtcaggtgg gccccgaagt ccaggtgcag
    20161 cagcgtgccg cagatctgct ggttgtccgc caggtgcgag cggagcgcac attactcagc
    20221 cagaaccgcg ggtcgccaag aggaccaacc gacagcagca gcgaacgagg caggccgcgc
    20281 gcttgcgatg cggtgtcttt cggccgtata tccggccaac cggtgtccca ggatcactgg
    20341 aagattcgtg gggtacggat acggctttcc ggagatctcg actgcgaggg ttggggatca
    20401 aggatggatg ccgggcaggg gcttcttgtt ctgatgggtt cgggggaaac cagtcccacg
    20461 atggtgacgt tgcaccggga gttggtggcg catctggagc cgggcgccga ggcagtgatc
    20521 ttggagaccc cgtacgggtt ccaggtgaac cgtgaggaca tctcgtcgcg ggcccgggag
    20581 tacttccggc gcagcgtggg gctcgtgacc acggtgatgg ctgatacgga cgccgatgtc
    20641 ccggcggagg tcgactccga caccctgcac gatcaactac accgagccgc ctgggtgttc
    20701 tgcggccccg gcagtccctc atacgcgctg cggcggtggc aggagcaggg acttggacag
    20761 gccctggccg accgagtgcg gcggggccgt ggggtgacgg tgatggcttc tgcggccgcg
    20821 tgcacggtgg ggctggtcgc actgcccgtg tacgaagtct acaaagccgg gcacccgccg
    20881 gtgtggctgg acggcttgga cctgctggag agtctcggcc ttccggtggc ggtgataccg
    20941 cactacgaca acgccgaggg cggtacacac gacacccgct tctgctacct cggcgagacg
    21001 aggctggtcg ctctggaaaa gcacctgcca ggggaaagcg ccgtcctcgg cattgatgag
    21061 cacaccgccg tcgtcatcga tctcggcgcc ggcagtgcgc gggtatgggg ccgtggagtg
    21121 atgacggtcc ggcgccgcgg ggccgtcacg gtgatccctt cgggcaccgt tgtgccgctg
    21181 gaccgattga ggcgcctcgt ggccggtact gcggcgaccc actcgcccgg actctgggag
    21241 gcgaccgagt cagtccagcc tgatgcgcca tcgtctgtcg gcgggccagt caccctccag
    21301 gaagccgtca ccgccgcgga cacgctcttc gagtcggcgc gggcggctcg tgacgccggc
    21361 gggatggtgg cggcaattct gcaactggag gcggagatca gctcgtggtc cggcgacacg
    21421 gaggaggacg aaggcgggca ggagtgggcg cggacgatcc tgcgcggaat gatccgccag
    21481 ctcgtcgccc ccgctcagca gggcatggcg gagccggagc gcaccttggg cagggtcctt
    21541 gacccgctgc tcgacctgcg cggggccctg cgggcccagg gggcctacga ccttgccgac
    21601 cgtctgcgta cgtcccttgc cgcaggcggt gtacggattc gcgacgatgc ccgaagcagt
    21661 cggtggcagc tcctgccggg tgaccacacc gcggcgatcg gggcggacga gcccaccggg
    21721 cctgcggagg accctcccat gacctgatgc ctaaaacatg caactgcgac gtagtggcaa
    21781 tagaatcggc ggcgggccgc ttcagcatcc cggcggctcc cccacggtcc tggagtcgac
    21841 gcatggttgc ctgcttgccg ccctccgcag acgggcaccg atgatgagcc ggacgcccgg
    21901 cgccgcgtcg acgcccccag tcctggtcga agcgctgcta ctgcggtacg acgcggtcac
    21961 cggcttcgcg taccgccgtt tgctgaccgc gctcggccgg tcctcggctc ctgatcgcgc
    22021 ggcccgccga ctggccggcc ttcccgatga cggcgaccac cacctcgtgc actccaccag
    22081 ttggcgtgcc gatgacgagg gggccatcgt gctgacctac gtcgtccacc ccgatcccga
    22141 ccctgatcgt cccgcgcgtc ctctggcgga tccgcacacc atcgcccgca gcaacaggac
    22201 gggccatccg gcgccgcccg acctgacggt cgatcatgtg gcttctcatg cggtcaggca
    22261 tctggcgctt ctggagagca ccgaccctgt ggttgccgcg ttcctcgcgg cccggccgca
    22321 ggcccaagac gctctgagcc gggtcagcgc ccttcccgcg ggtcagctcc gatcagcacc
    22381 gacgtgctcg aacccgcggt agcccgggtg aactcgccgg gaactgccag atcgtggcgt
    22441 ccacctcgtc ccgaggtggc aagcgggcgg cgctgatgcc gattctcgtt gacggagaag
    22501 ttgccgagcg gatggacctg ggctccggtg gctaccggtg ccccgcatgg ggcggtgcga
    22561 tgccatggga aggcccttcg ggagcggcaa ggttgcgtga ggtcccgtcg cgcgggaacg
    22621 gcgcgcagca gcggggccgc agccgcgccc cggtagaagg c
//
