LOCUS       NZ_SPGD01000024        26430 bp    DNA     linear   CON 20-MAY-2024
DEFINITION  Streptococcus anginosus strain 1001175st1_H11
            NODE_24_length_30909_cov_89.5242, whole genome shotgun sequence.
ACCESSION   NZ_SPGD01000024
VERSION     NZ_SPGD01000024.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus anginosus
  ORGANISM  Streptococcus anginosus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus; Streptococcus anginosus group.
REFERENCE   1  (bases 1 to 30909)
  AUTHORS   Yang,C., Faith,J. and Aggarwala,V.
  TITLE     Strain-level differences in gut microbiome composition determine
            fecal IgA levels and are modifiable by gut microbiota manipulation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 30909)
  AUTHORS   Yang,C., Faith,J. and Aggarwala,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Genetics and Genomic Sciences, Icahn School
            of Medicine at Mount Sinai, 1470 Madison Ave, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.9707156971x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005844435.1-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 01:50:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 73 of 151
            Pseudo Genes (internal stop)      :: 52 of 151
            Pseudo Genes (multiple problems)  :: 40 of 151
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:21:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4479
            Orig. end                         :: 30909
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SPGD01000024.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26430
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..26430
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26430
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21173](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21173)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            598..1050
                     /locus_tag="FGQ50_RS08710"
     CDS             598..1050
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004182172.1"
                     /locus_tag="FGQ50_RS08710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_045758971.1"
                     /transl_table=11
                     /translation="MFNNDTFGDRLKELRKSKKLTQVQVSEMIGVQQGTYSRWENGTLE
                     PNLEAVVKLAKLFDTTTDYLLGKTIYSTLDVIPHPITRIDMKKLKEFNKTELNDLKFAI
                     VMNGIKNHSTLPKYLDELVSENNLDEEEQEILHTLFKEVCDYFNAD"
     gene            1255..1809
                     /locus_tag="FGQ50_RS08715"
     CDS             1255..1809
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712748.1"
                     /locus_tag="FGQ50_RS08715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_138284339.1"
                     /transl_table=11
                     /translation="MNNSYILLRHAHSRFSSDDFNRTLSEKGFASLKQLEFLNSFNIDY
                     YFSSPYKRAFETVNSSPVQFDKIVLDDRLRERKLSSRFIEDSEFEETIQYLWQNPDKSL
                     IGGESNQEALMRILDLLQDLEERYSGKTILLSSHGNLLGILINHFDSSFDYQKWEQMTF
                     PDCFLIDKDESVKKIMKVTSG"
     gene            complement(2122..>2977)
                     /locus_tag="FGQ50_RS08720"
                     /pseudo=""
     CDS             complement(2122..>2977)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307576.1"
                     /locus_tag="FGQ50_RS08720"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ELYQTWYVLKVRLKKKL"
     gene            3336..4073
                     /locus_tag="FGQ50_RS08725"
     CDS             3336..4073
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896626.1"
                     /locus_tag="FGQ50_RS08725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_024053183.1"
                     /transl_table=11
                     /translation="MYQIKEAAQLSGVSVKTLHHYDKIGLLVPQKSENGYRLYSEVDLE
                     RLQIILFYKYLGFSLKKIAELLSQEEQELLPHLNKQLQFLQQEREHLDTLISTLQKTIQ
                     AQKGERKMTTQEKFVGFTYEDHANYYHQAVETYGQEVMDDSRARQVGKETEMTEAFNKV
                     FRNLANNMQKGLAVEAQENLSEAEQLFQAMNTYAFDCSLEVFAFIGKGYVANPEFKKNI
                     DQFGVGTAQYVADIIHIYVTQAK"
     gene            complement(4124..5296)
                     /locus_tag="FGQ50_RS08730"
     CDS             complement(4124..5296)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041648.1"
                     /locus_tag="FGQ50_RS08730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_070584599.1"
                     /transl_table=11
                     /translation="MNHFDTIVIGGGPAGMMAAISSSFHGQKTLLLEKNKRLGKKLAGT
                     GGGRCNVTNNGTLEDLLAGIPENGRFLYSVFSQFDNHDIMNFFTDNGVALKVEHHGRVF
                     PTTDKSFTIIEALERKMKELGVTIMTQTEVVSVKKNADYFIIKSSERIWSCDRLIVTTG
                     GKSYPSTGSTGFGYEIARHFNHTITELEAAESPLLTDFPHKALQGISLANVTLRYNKHI
                     ITHDLLFTHFGLSGPAALRFSSFLKGGETIYLDVLPQFSAEDLAAFLENNREKSLKNSL
                     KQLLPERLADFFAQPFLKKGKQLTGKEKEELIQQLKALPIPITGKMSLAKSFVTKGGVS
                     LKEINPKTLESKLVPGLYFAGEVLDINAHTGGFNITVALCTGWVAGSVEY"
     gene            5441..5935
                     /locus_tag="FGQ50_RS08735"
     CDS             5441..5935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896624.1"
                     /locus_tag="FGQ50_RS08735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF536 domain-containing protein"
                     /protein_id="WP_003027119.1"
                     /transl_table=11
                     /translation="MAIEKTVSELAEILGISRQAMNNRVKTLAPEDTDKNEKGVTVVTR
                     SGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEIVRLYDQLKAKDAQLAKKD
                     EQLRVKDVQIAEKDKQLDQQQQLTAKAMSERETLLLELDEAKEKVQAQEQKGFFARLFG
                     R"
     gene            5975..>6145
                     /locus_tag="FGQ50_RS08740"
                     /pseudo=""
     CDS             5975..>6145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016670380.1"
                     /locus_tag="FGQ50_RS08740"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="YdcF family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKDVMKEKVAKNINILASFCGKRDLPELTQKALEDKYSLKQADVR
                     VLFSRSILVGGD"
     gene            <6215..7852
                     /locus_tag="FGQ50_RS08745"
                     /pseudo=""
     CDS             <6215..7852
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919735.1"
                     /locus_tag="FGQ50_RS08745"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="glycerophosphodiester phosphodiesterase"
                     /pseudo=""
                     /transl_table=11
                     /translation="AAGTLLRQTG"
     misc_feature    6217..6230
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            complement(7907..8206)
                     /locus_tag="FGQ50_RS08750"
     CDS             complement(7907..8206)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /locus_tag="FGQ50_RS08750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="WP_024053178.1"
                     /transl_table=11
                     /translation="MMNMQSMMKQAQKLQKQMEKGQAELVATEFVGKSAQDLVVATLTG
                     DKKVVKIDFQEAVVDPEDLETLSDMTTQAINAALVEIDAATKKKLGAFAGKMPF"
     gene            complement(8243..10522)
                     /locus_tag="FGQ50_RS08755"
     CDS             complement(8243..10522)
                     /EC_number="3.4.14.11"
                     /GO_function="GO:0008239 - dipeptidyl-peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003070953.1"
                     /locus_tag="FGQ50_RS08755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="WP_024053177.1"
                     /transl_table=11
                     /translation="MRYNQYSYTPETSEKILAEMESIGFSFRPEHSDKENLETFVRRTF
                     FNYKNTDYALKSLVANSNTDLLSFFTSKQELTAEIFYTIAFQLLEFVPFVDFDEVKTFR
                     KDINFPITYGNLLENLYQLLNTRTKNGNLLIDKLVSDGLIPEDNTYHYFNGKSLATFTS
                     HNAIREVVYVESRVDTDEDELPDLIKVSIIRPHFDGQIPAVMTASPYHQGTNDKASDKA
                     LYNMNVNLVKKETEKITIHDSEVCLVEPQGQAVLVEQSEETLGHIGTYTLNDYLLSRGF
                     ANLYVSGVGTKDSEGLMTSGDYYQIEAYKNVIDWLNGRCRAFTDHTRQREIKATWSNGK
                     VATTGISYLGTLSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDS
                     LTELTYSRNLLAGERLRHNVEYQKSLKTLKANLERETGDYNQFWHDRNYLIHAHKVKAE
                     VVFTHGSQDWNVKPLNVYNMFHALPQDIKKHLFFHNGAHIYMNNWQSIDFRESMNALLS
                     KKLLGYNSHFELPTVIWQDNSQAQSWLSLKNFGNQEHYTHFNLGSTTQDIQNAYSDTDY
                     KRFSKTYQTFKNELFDGKVNQVTVDFTLEKDLFLNGPAKLNLRLKSSTDKGLISAQLLD
                     LGQAKRLTPIPGVLTPKVMDNGRVYMLDHLMELPFKETPHRVVTKGFLNLQNRNDLLTV
                     EEVTPDQWLEFSFELQPTIYKMKIGDTLRLVLYTTDFEHTVRDNTDYHLTIDLANSSLD
                     VPDMVK"
     misc_feature    complement(10543..10556)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.34"
                     /tool="antismash"
     misc_feature    10605..10618
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.69"
                     /tool="antismash"
     gene            10632..11483
                     /gene="gla"
                     /locus_tag="FGQ50_RS08760"
     CDS             10632..11483
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gla"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269234.1"
                     /locus_tag="FGQ50_RS08760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aquaglyceroporin Gla"
                     /protein_id="WP_024053176.1"
                     /transl_table=11
                     /translation="MDVTWIVKYITEFLGTAILIILGNGAVANVELKGTKGHQSGWLVI
                     AVGYGMGVMIPALMFGNVSGNHINPAFTLGLAISGYFPWAQVAPYIIAQLLGAIFGQAL
                     VVASHRPYYLQTTNPNAILGSFSTIVNTDDGSKKSHAASMINGFVNEFIGSFILFFAAM
                     AMTKNYFGAEVVKYAATRGVDATQIQGKVAIGSHINAGLAVAHLALGFLVMALVTSLGG
                     PTGPGLNPARDLGPRILHFLLPKSVLGKHKGDSKWWYAWVPVVSPILAGIAAVALYKII
                     YG"
     misc_feature    complement(10649..10664)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(10673..10687)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.89"
                     /tool="antismash"
     gene            11700..12965
                     /locus_tag="FGQ50_RS08765"
     CDS             11700..12965
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270644.1"
                     /locus_tag="FGQ50_RS08765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_070241493.1"
                     /transl_table=11
                     /translation="MELDKLSGRRTLLFGILAILFGVIIIANGVDFAKFALDLLVIYFL
                     FVGVINLFFRFLVKQNRISLGSALLHVLVGLVVGFLNRASNLPVNIVIIILGCYQLCTA
                     AIYGITYLLYRQNKLKGGFRYLFDTFLYGGIGLTPVFSPSMDGRMQFLIIGIYLILLGF
                     SNVRDGLMFNTDVEKKQLRRRIRINLPIIIAAFFPAEQLNRFNRFWQGEKRKPQKVYSR
                     VRDEEKPIDLEVLIHTSDQNLFGMIGHVDICYKGKVVSYGSYDIFSERLFGTIGDGVLF
                     KVDKDAYIDLCKEESKKTLFGYGLSLTDEQKRAVEKRLAEIDELLEVWNPPADLKDGKR
                     TYAYKLKHELGGRLYKFKTSRFKTYFILSTNCCLLADSIIGQAGTAILDMRGIIAPGTY
                     QSYLQYEFESANELVVAQNIYQ"
     gene            13047..13787
                     /locus_tag="FGQ50_RS08770"
     CDS             13047..13787
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027094.1"
                     /locus_tag="FGQ50_RS08770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CppA N-terminal domain-containing protein"
                     /protein_id="WP_024053175.1"
                     /transl_table=11
                     /translation="MCSTNKSVNTIPVLKINNRKNNLAFYCQTLGMKNLLEEGAFVSLG
                     DQTKVEKLQLEESPSMRTRKVVGTKKLAKIVIKVANPREIEALLARGSKVDYLYQGDNG
                     YAFEATSPEGDRFLLHSEKDWTALQRVMIAPAFAPLEDFVGLSQFTIEQIHINAPDKEK
                     AVTFYQEWLGNQSILTFSQASGPDLLTESTQTWDLAMVKFTVEQFDVEALRDLFQGREN
                     FIPKSGKFFLTKDESQIEAWIEAV"
     gene            13784..14719
                     /locus_tag="FGQ50_RS08775"
     CDS             13784..14719
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543678.1"
                     /locus_tag="FGQ50_RS08775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_024053174.1"
                     /transl_table=11
                     /translation="MSSSKILSKVGEQIAQQIYPGASLALYTRGEWQEYYLGESNPERG
                     EKTQAGLVYDLASVSKVVGVGTILAVLFHEEKLDLDAPLTQYYPAFHDNSVTVGQLAAH
                     TSGLDPFIPNRDALNAVELKEALNHLKVLDNKHFRYTDVNFLLLGFMVEEIFHSSLSDI
                     FERKIFQSWGMKETTFGPVAQAVPTVRGVKAGVVHDPKAHVLGRHAGSAGLFSTVRDLE
                     LFLEHYLQDDFAATLTKNFSKEIGKTRSLAWDLDKEWLQHTGYTGTFIMFNRLQQKAVI
                     FLSNRTYEKDERAQWILDRNELMDLIKQNL"
     gene            14882..15760
                     /gene="mvk"
                     /locus_tag="FGQ50_RS08780"
     CDS             14882..15760
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /locus_tag="FGQ50_RS08780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mevalonate kinase"
                     /protein_id="WP_070584595.1"
                     /transl_table=11
                     /translation="MTKKVGVGRAHSKIILIGEHAVVYGYPALALPLTNIEVTCRILPS
                     DHAWILYEEDTLSMAVFASLEFLGVQEAYIRCEIESMVPEKRGMGSSAAVSIAAIRAVF
                     DYYEQELDRETLEILANRAEMIAHMNPSGLDAKTCLSDHAIKFIKNVGFSEFETNLGAY
                     LLIADTGIYGHTREAIQKVESIGRRALPHLHQLGKLTNEVEEALKVKDLERIGIAMSEA
                     HLSLKNLDVSCPEADWLVATAQENGALGAKMSGGGLGGCIIALVASKEKAVSLADLLRE
                     KGAVNTWIESL"
     gene            15742..16686
                     /gene="mvaD"
                     /locus_tag="FGQ50_RS08785"
     CDS             15742..16686
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077756.1"
                     /locus_tag="FGQ50_RS08785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_024053172.1"
                     /transl_table=11
                     /translation="MDRKSVKVRSYANIAIIKYWGKKDTVKIIPATSSISLTLENMYTE
                     TTLSSLPASAQSDEFYINGVLQDQAEHKKMRNIVDRFRPQGAGFVRIDTKNNMPTAAGL
                     SSSSSGLSALVKACNDFFELHLSTKEQAQKAKLASGSSSRSFYGPIAAWDKDSGEIYPV
                     KTDLKLAMIMLVLYDHKKPISSREGMKRCAETSTTFSDWVRQSEEDYKAMLTYLSNNDF
                     AKVGELTEKNALAMHATTQTATPAFSYLTEKSYEAMDFIKQLRSQGEHCYFTMDAGPNV
                     KVLCLEEDLEHLVPIFAERYHLIVSKTKELPDD"
     gene            16679..17677
                     /locus_tag="FGQ50_RS08790"
     CDS             16679..17677
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074659.1"
                     /locus_tag="FGQ50_RS08790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_024053171.1"
                     /transl_table=11
                     /translation="MTKTVRTCGKLYLAGEYSVLTAGQGAILKNIPIYMTGKIHFSERY
                     QLFSDMFDHTVDLTPDDEYSLIQDTVAVMNEFLQIRFISLRPFFLTITGKMEQDGKKFG
                     LGSSGSVVVLTIRAITALYGLALSAEETFKLAAYVLLKRGDNGSMGDVACIAYEDLIYY
                     QSFNRKKIAEQINELPLEKIVTQDWGYIIRTIHPQLPCDFLVGWTREPAISSVLINQVK
                     AKISSSFLTQTQEEVLRLEKALFVGEKEIVKQSLEKVSCLLLQLSPAIYNEKLRALKRS
                     SQGLDCVAKSSGAGGGDCGIALSFDSEASQILVERWQAAGIEVLYKERWDR"
     gene            17674..18690
                     /gene="fni"
                     /locus_tag="FGQ50_RS08795"
     CDS             17674..18690
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269119.1"
                     /locus_tag="FGQ50_RS08795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_024053170.1"
                     /transl_table=11
                     /translation="MSRNRKDEHIRYALEYDSPYNSFDDMELIHCSLPKYDLGEIDLTT
                     QFAGRDWEFPFYINAMTGGSEKGKDINQRLAQVAEACGILFVTGSYSAALNNPTDDSYA
                     VSKGKSDLLLATNIGVDKPYSLGQQAITDLHPLFLQVHVNLIQELLMPEGERSFKTWRA
                     HLKDYAEQSSVPVVLKEVGFGMDLATIEIAYDLGIRTVDLSGRGGTSFAYIENRRGGNR
                     DYLNDWGQSTLQALLNAQPMMDKMDILVSGGVRQPLDMVKAFVLGAKAVGLSRTMLELI
                     ETHSVDEVITIVNGWKEDLRLIMCALGCQNLRELRQVPYLLYGRLREAQGQLNKEIR"
     gene            complement(18719..19999)
                     /locus_tag="FGQ50_RS08800"
     CDS             complement(18719..19999)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077459.1"
                     /locus_tag="FGQ50_RS08800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_070241495.1"
                     /transl_table=11
                     /translation="MKISWTGFSKKSLQERLQILKDYHLLNEDNQTNLEHNHMLPLSTA
                     DQMSENVLATFALPYSFVPDVVVDEEVYQVPFVTEEPSVVAAASFAAKIIKRSGGFKTT
                     IHNRQMIGQVALYQVANIEVAIKNIQNHKQELLELANQAHPSIVNRGGGACDLRVEWLN
                     GEAEFLVVYLTVDTQEAMGANILNTMLEALKTPLEELTGGESLMAILSNYATEALVTAT
                     CEIDIRFLDRNKSEALDIAKKIVLASQFAKQDPYRASTHNKGIFNGIDAVVLATGNDWR
                     AIEAGAHTYASRNGSYQGLTTWSIKEATQTLCGEITLPLPIATKGGSIGLNPTVEVSFD
                     LLKQPTAKEFASIIASIGLAQNFAALKALVSTGIQHGHMKLQAKSLALLAGAKDTEIAP
                     LISQLVSEKHFSLKRAQEILENIRQKS"
     gene            complement(20001..21173)
                     /locus_tag="FGQ50_RS08805"
     CDS             complement(20001..21173)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032978.1"
                     /locus_tag="FGQ50_RS08805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_024051457.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.9e-09,
                     bitscore: 28.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIGIDKIGFATANYVLKLENLAAARNIDPEKLSKGLLLKEISIA
                     PVTEDIVTMGASAAASILNEEDKQAIDMVIVASESGIDQSKASAVFVHGLLGIQPFARS
                     FEMKEACYSATAALDYAKLHVEKHPNSKVLVIASDIAKYGIETPGEPTQGAGAVAMLIT
                     SNPRILSFNEDNVAQTRDIMDFWRPNYSTTPFVNGMYSTQQYLDSLKTTWAEYQKHNQV
                     SLKDFAAVCFHLPYPKLALKGMKKIMDKSLPSEQQAQLQENFEQSILYSQKVGNIYTGS
                     LFLGLLSLLENSTTLKAGDRIALFSYGSGAVSEIFSGQLVAGFEQQLETNRMEILNKRT
                     PLSIPDYEKIFFEEASLDENGSASFTNYENQDFALAEIVEHQRRYIKVEK"
     gene            complement(21307..21756)
                     /locus_tag="FGQ50_RS08810"
     CDS             complement(21307..21756)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029423.1"
                     /locus_tag="FGQ50_RS08810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_101749897.1"
                     /transl_table=11
                     /translation="MKPLTVLLQAAASFLAIVMFLIVLNIQKRMLIPGGILGMFIWLLY
                     YVLKGPTNVIIATFIAAIIGSCISQVLSILYKTPAVVFILAILAPLVPGYLSYRTTAFF
                     VTGDYSHAMINATLVVILALVISIGMASGTVVLRLYHYLQKHRSS"
     gene            complement(21760..22536)
                     /locus_tag="FGQ50_RS08815"
     CDS             complement(21760..22536)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027066.1"
                     /locus_tag="FGQ50_RS08815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_024051455.1"
                     /transl_table=11
                     /translation="MVEKKDVEREDKFNLTVDVLMLAGTLLLQSGSEIYRVEDTMIRIA
                     HSQGIMDCNALAMPVAIFFSIENTNISRMKRITHSNYNIEKVCDVNQVSRELVSGDISL
                     EDAFEKLTQLKKKKTPYTNRQLTFAATISAPFFSIMFGGNLYDALGAALATFFGFAFSL
                     SVNKYVRIPFVTAFAGAFIFGLLAQIWARYSGFPSSADLIIAGAVMPFVPGIALTNAVR
                     DLMTNHLNSGMSKIFETLLITLALGAGTSVALVLMK"
     gene            complement(22637..24952)
                     /gene="pflB"
                     /locus_tag="FGQ50_RS08820"
     CDS             complement(22637..24952)
                     /EC_number="2.3.1.54"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008861 - formate C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006113 - fermentation [Evidence IEA]"
                     /GO_process="GO:0015942 - formate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pflB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999778.1"
                     /locus_tag="FGQ50_RS08820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="formate C-acetyltransferase"
                     /protein_id="WP_024051454.1"
                     /transl_table=11
                     /translation="MVVKTVVEAQDVFDKAWEGFKGEDWREKASVSRFVQANYTPYDGD
                     ESFLAGPTERSLHIKKIIEDTKAHYEETRFPMDTRATSIADIPAGYIDKDNELIYGIQN
                     DELFKLNFMPKGGIRMAETALKEHGYEPDPKMHEIFTKYVTTVNDGIFRAYTTNIRRAR
                     HAHTVTGLPDAYSRGRIIGVYARLALYGADYLMAEKVEDWNALTDIDEETIRLREEVNL
                     QYQSLKEVVRLGDLYGLDVRRPAMNVKEAIQWVNVAFMAVCRVVNGAATSLGRVPIVLD
                     IYAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDQLYSGDPTFITTSMAGMGN
                     DGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYSFRHYCMHMSHKHSSIQYEGV
                     TTMAKDGYGEMSCISCCVSPLDPENEDQRHNIQYFGARVNVLKALLTGLNGGYDDVHKD
                     YKVFDIDPISDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEAVQMAFLP
                     THQRANMGFGICGFANTVDTLSAIKYATVKPIRDENGYIYDYETTGEYPRWGEDDPRSN
                     ELAEWLIEAYTTRLRSHRLYKNAEATVSLLTITSNVAYSKQTGNSPVHKGVYLNEDGSV
                     NLSKLEFFSPGANPSNKARGGWLQNLNSLASLDFGYAADGISLTTQVSPRALGKTREEQ
                     VDNLVTILDGYFENGGQHVNLNVMDLKDVYDKIMNGEDVIVRISGYCVNTKYLTKEQKT
                     ELTQRVFHEVLSMDDALS"
     gene            25202..26269
                     /gene="dinB"
                     /locus_tag="FGQ50_RS08825"
     CDS             25202..26269
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="dinB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003034065.1"
                     /locus_tag="FGQ50_RS08825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA polymerase IV"
                     /protein_id="WP_024051453.1"
                     /transl_table=11
                     /translation="MLIFPLINDTSRKIIHIDMDAFFASVEERDNPALKGKSVIIGADP
                     RLTGGRGVVSTCNYEARKFGVHSAMSSKEAYERCPQAIFISGNYEKYQAVSQQIRAIFK
                     RYTDVIEPISIDEAYLDVTKNKLGMKSAVKIAKLIQHEIWTELHLTSSAGVSYNKFLAK
                     IASDYEKPHGLTVILPEEAEAFLSQMDVAKFYGVGKKTVEKLHDMGVYIGADLLEIPEM
                     TLIDLFGRFGFDLYRKARGISNSPVKVNRIRKSIGKERTYGKLLHNEDDIKKELTLLSQ
                     KVARSLKKHGKSGRTIVLKIRYADFSTLTKRQSLATRTQDAEQIERIAHEIYDSLDEQT
                     KGVRLLGVIVTGFGM"
     misc_feature    complement(25237..25252)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 23.02"
                     /tool="antismash"
ORIGIN
        1 cattgtctgc tagactccca aatacggctt gtatagcttc ttttagacct atttcaagtt
       61 ttagtttagc taatttttga aattgtctaa ggtcttcgtc tgtaaagtca taggtaactg
      121 tataacttaa ttgatgggtt ctgggatttc tactgatagg aattttgatt tttttaaatt
      181 ccttgccact tatctcttta atcagtttaa tccaattttt aagagtagag gtagagttta
      241 ggccagaaat ttgattgact aactctttat tggtcatctt tttgtgaaac ctccgaaatt
      301 ttcttgtgca actgaagagt tttctgtggt ataattgtta cataatatgt tttgatcttg
      361 gaacgaacgg cacatttgtt tcaagatttt tttattttgt cgaatcttac ctcctttatt
      421 aaaatttttt aaatcgacta ctagttacat acgcttttac ctccttttat gctataatat
      481 tctcaatgga atatttaatc ttaaaataaa tattccttat ggaataattc cgttttatac
      541 cgtttagaat attttgtcaa gtcaaaatat accgaatcga atatttaaga ggatacaatg
      601 tttaataatg atacttttgg agatcgtctt aaggaactga gaaagagtaa gaagttaact
      661 caagtacaag tttctgagat gattggtgtg caacaaggga cttattctcg ttgggagaat
      721 ggaactttag agcctaattt agaagctgtt gtcaaattag cgaagttgtt tgatacaacg
      781 acagattatt tattaggaaa aaccatttac agtactctag atgttattcc tcatccaatt
      841 actagaattg atatgaagaa gttaaaagag tttaataaaa ctgaactaaa tgatctgaaa
      901 tttgcgattg ttatgaatgg aattaaaaac cattctactc tacctaagta tttggatgag
      961 ctagtctctg aaaataattt agatgaagaa gagcaagaaa tattgcatac cctttttaaa
     1021 gaggtttgtg attattttaa tgcagattga aagtttattt gattaacact ccgtaactga
     1081 actgcatccc aaaagttaga ttttttctgt ctaacttttt ggggtcagta caattgtgtg
     1141 gtttttttgt gagtaaaatg aatgaatcta tttgacaatt atagttaagt aagataatat
     1201 gagcttataa aacaactttc ttccttatat gtattttcag cgtaattata atttatgaac
     1261 aattcttata ttttacttag acatgcccat tcgagatttt cgagtgatga ttttaataga
     1321 actttatcgg aaaaaggatt tgcatctctt aagcagttgg agtttttgaa ttcttttaat
     1381 attgattact atttttctag tccttataag cgagcttttg agacagtaaa tagttctcct
     1441 gtacaatttg ataagatagt gcttgatgat cgtttgcgtg aaagaaaatt atcctcaaga
     1501 tttattgagg attctgagtt tgaagaaacg attcaatatt tatggcaaaa tccagataaa
     1561 tcgcttattg gaggtgagtc taatcaagaa gcattaatga gaatcttaga tttattgcag
     1621 gatttagaag aaaggtattc aggtaaaact attttactaa gttctcatgg aaatttgcta
     1681 ggaatcttaa tcaatcattt tgattcaagt tttgattatc aaaaatggga acagatgact
     1741 tttccagatt gctttctaat tgacaaagat gagagtgtga aaaaaattat gaaagttact
     1801 tctgggtaat catttagttc aatctatctg attttatttg atactgtcaa taatttggtg
     1861 taaattaaag ggatggagtg ttaccaaaga gttactaaaa tttgaaaaat gagtctattt
     1921 tgcaagattt aaaagtctta aaactctatt atatcaaggt tataagattt aaaaaatgta
     1981 ttcatagaac tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt
     2041 attgcttgag tttagaaaaa gtcttgatac acaaggcttt ttttgatgtt tttctttatc
     2101 gtaccccaaa ttgtacccca attatagtct atccatgata gattctacct ctttgaactc
     2161 tttatcaatt ctttctgtca tagtatgacc atatgccttt atcaacattt ggatatcttt
     2221 atgacctaaa attttagcca caactcccat atctatatga ctatgaagta aatatgagcc
     2281 ataagtgtgt ctaagtcctt gttctagacc atagtgaaag aagagaaatt tctctttgtt
     2341 tttatttgta gtaatgagtt tattcttttt cgttctttta tcatgttagg cagaacagta
     2401 actgttttat catctattgg tactgctcgt atggagtatc attttttgct ttcgtccccc
     2461 catgtcgcag tgttatatct tctatgtgtg tataaataat ggtcttctaa ctttgtatca
     2521 tcatcagtta tatcacttgc ttctccatac ctcatgcctg ttttagctat gatatataga
     2581 acatgatata taactgttgt ctcataatct aatttttctt ccagatagtt tactaatcta
     2641 tgataatcct caacactatg aatatatttt tcctcgtttt tttgagtttc ctttcctgcg
     2701 aagcgttcta cgttacttgt gaaatcatca agaactatct tatcagattg cactaattgt
     2761 atagtttttc taattgttga attgattcta cttaagtaat catatccaac agtttcccca
     2821 tggatattca tggttctttg atattctgtc gattttatat caactattgc tttatcttca
     2881 aatagttttt ttattgtttc tccataaatc tgctaatttt tctttataac ttctttttaa
     2941 gtctaacttt taagacatac caagtttgat ataattcaag tcaatgtttg ttacaatttt
     3001 cttttcttcc ttaattgatt tgtgatctta tctagatcaa ttagagttta aaaattgaaa
     3061 atttgtagtt gttagtctcg tcttcgaaag gtttcgacaa tccaataggc tgttgaagta
     3121 gtgaaggaag caaacgaagc ttttagtttg agtagtgttc gtccaagttt gaaaagcgaa
     3181 tggtgttgag atttgctttg caagcaacgt tagcgatttt tgtaaaaagc aaggtcgtac
     3241 tttgtgataa ctatattggg aggaaaatat ttttaaaaaa gtatttactt tgacctaagg
     3301 ggagggttta taatgagatt tgtaaggagg aaatgatgta tcaaatcaaa gaagctgcgc
     3361 agctttcagg tgtttctgtc aaaacactgc atcactatga taaaataggt ttgcttgtgc
     3421 cgcaaaagtc tgaaaacggg tatcgccttt atagtgaagt agatttagag cgcctgcaaa
     3481 ttattttatt ttacaaatat cttggatttt ctttaaagaa aatagcagag ctgctaagtc
     3541 aggaagagca ggaactattg cctcacttga acaagcaatt gcagtttttg cagcaggaaa
     3601 gggaacattt ggataccttg atttccacct tacaaaagac aattcaagct caaaaaggag
     3661 aaagaaaaat gacgacacaa gaaaaatttg ttggatttac ctacgaagat catgcaaatt
     3721 attatcatca agcggttgaa acatacggtc aagaagtaat ggacgattct cgtgcacgac
     3781 aagttggcaa agaaactgag atgacggaag catttaacaa agtttttcgc aatctagcta
     3841 acaatatgca aaaaggtcta gctgtggaag cacaagagaa tttatcagaa gccgagcagt
     3901 tatttcaagc aatgaatacc tatgcctttg attgctctct ggaagttttc gcttttatcg
     3961 gaaaaggcta tgtggcaaat ccagaattta agaaaaatat tgaccaattt ggagttggaa
     4021 cagcccaata tgtagcagat attatccaca tctacgttac acaagcaaaa taaaaaatag
     4081 ggcaggtgcc aacatgttct gcatggtagc atctgctcta tttttagtat tccacacttc
     4141 cagcgaccca gccagtacag agagcgactg taatattaaa tccaccagta tgagcattga
     4201 tgtccagcac ttcgccagca aaataaagcc caggaactag tttgctttct aaagtcttgg
     4261 gattgatttc cttaagactg acaccgcctt tggtcacaaa agatttagct agagacattt
     4321 tgccggtaat aggaattggt agagctttga gttgttgaat gagctcttct ttttcttttc
     4381 cagtcaattg tttgcctttt ttaaggaatg gctgcgcgaa aaagtctgcc agacgttcag
     4441 gaagtaattg tttgaggcta tttttgagcg atttttctcg gttattttct aaaaatgctg
     4501 ccaaatcttc cgcagaaaac tgtggtaaga catctaaata aatggtttca ccgcctttga
     4561 ggaaactgga gaaccgcaat gcggcaggac ctgacaagcc gaagtgggta aaaagcaagt
     4621 catgggtaat gatgtgttta ttataacgaa gggtgacatt ggctaatgaa atcccctgta
     4681 aagccttgtg tggaaaatct gtcaaaagtg ggctttctgc agcttctaac tctgttattg
     4741 tatggttgaa atggcgcgca atctcatagc caaagccagt agagccagtt gagggatagg
     4801 attttccacc tgttgtgaca atcaatcgat cgcagctcca aatgcgctca cttgacttga
     4861 tgataaagta atccgcattt ttctttacag aaaccacttc cgtctgggtc atgatggtga
     4921 cgcctagctc cttcattttc cgttctaatg cttcaataat tgtaaaagat ttatctgttg
     4981 ttgggaaaac tcgcccgtga tgctctactt tgagtgcaac accattgtca gtgaaaaaat
     5041 tcataatgtc atgattgtca aactgggaaa agacgctgta gagaaagcgc ccattttctg
     5101 gtatgccagc taataaatct tctaaagtgc cgttattcgt cacattgcag cgtccgccac
     5161 cagttccagc gagcttctta cccaagcgtt tatttttttc taagagcagt gtcttttgtc
     5221 catgaaagga gctggaaata gcagccatca taccagctgg tcctccgcct atcacgattg
     5281 tatcaaaatg gttcattgtg cttctttctt taaatgaata tgtcaaattt attgtatcat
     5341 aaatgtgatg aaattccttg aaatccagag cgaatttgac agttaagcct tgatatgata
     5401 agatttaggt atatatctag aaaaagtttc agaggaaatt atggcaattg aaaagacagt
     5461 cagcgagcta gccgagattt tagggattag ccgtcaggcg atgaacaatc gggtcaaaac
     5521 tcttgcgccc gaagataccg acaagaatga aaaaggggtc accgttgtga cgcgcagcgg
     5581 tttgataaag ctggaagaaa tttacaaaaa gacgattttt gaagatgaac cggtcagcga
     5641 agatgtcaag caacgtgaac tcatggaaat tttggtagat gagaaaaatg cagaaattgt
     5701 gcgtttgtat gaccagttaa aagcaaaaga tgctcaatta gctaaaaaag atgagcaatt
     5761 gcgcgtgaaa gatgtgcaaa ttgctgaaaa agacaagcaa ttagaccagc agcagcaatt
     5821 gactgctaag gccatgagtg agcgtgaaac tttgctatta gaattggacg aagctaaaga
     5881 aaaagtgcaa gcacaagagc agaaaggttt ttttgcaaga ttgtttggac gatagagaga
     5941 atctcggttg aagaaactga gattttttta tagaatgaaa gatgtgatga aagaaaaagt
     6001 cgcaaaaaat atcaatattc ttgcttcttt ttgcgggaag cgagatttac cagaattaac
     6061 acagaaagct ttagaagata aatatagcct aaaacaggct gatgtcaggg tgctgtttag
     6121 taggagtatt ctagtgggtg gagattccga cagaggtcag aatagctttt gaagcattaa
     6181 aacaagatta tgctgactta atccgtctta tgctgcggca ggtactttgc ttcgtcagac
     6241 gggttaaatt tctgtcgtat aacaatgtag ttggagtgtt gtctagtcat cctctagtta
     6301 ctctggcttt tatcctcttg tttttagcca atctgttggt cgcttatgtt caaatcacac
     6361 ttcttttttt aggagcgcac aatctattga ctcaagacaa gcgaaccctc ttgaagttta
     6421 ccaagaaaac catagcagac agtttactca tcttaaagca ggcacgtcct agtaaaatct
     6481 tgtttgtctt gctctacatc gctctgctct ttcattttct ccgaaaaatc ctcaaaattt
     6541 actatataaa caagatttta gttccaaatt ttatcttaac ttatttgaaa gagacgtatt
     6601 tttgggggtg ctgtcgtcct gcccctactt gtatggctga tgttattgat tgcggtcaag
     6661 ctgatgttcg ccttgcccaa aatctttttt gaaaattctt ccgtaagaga agcggtgcgg
     6721 ttcagcttag aaaagaccaa aaaacgaact ttcttttatt cttggcagtt gttttggatt
     6781 gtgaccaaga cttttctctt ttttttggaa tggctcttcc tctctttttt tacagcatgt
     6841 tgcagacggt cattccaatc aagtgtcaac gattgctggt gtgatgaatt atgtgttgct
     6901 gaagaatgct cactatctga tgttgagcta tttcttgatt aaatttgttt cttttctgac
     6961 tgagcaaggt ttggcggatt atccgcggag gaagttcgat cgcgttttgc gctggcttgt
     7021 gatttccatt gcttctatat tctttgctgt ggaaggttat atgtatctca tttttccatt
     7081 agaaacggtt cctgttacga tttctcaccg aggagtgtcg caggaaaatg gtgtacaaaa
     7141 tacgattcag tcattggaaa agacggcttt gctgaaacta gattacattg aaatggatgt
     7201 acaagaaaca aaagatggtc aatttgtcat gatgcatgat gctaatcttt tcaatttggc
     7261 gggtgtcaat gcaagtccac aggatttgac catggcagaa ctaactgctt tagatgtttc
     7321 agaaaatggc tatcggacca aaatttccag ttttgatgcg tatctcaaac gtgccaacga
     7381 attgggacag cggttgctca ttgaaatcaa aaccagcaaa aaagattctt cggatatgat
     7441 ggagcgcttt ttgaaaaaat atggcccaac gattaaaaag tacggtcatc aaatgcactc
     7501 attggactat tgcgtgattg aaaaagttgt gaaatacgat gctagcatta aaagcttttt
     7561 tatcctgcct tataatacaa tcttcccacg aaccaaagcc agtggttata ctatggaata
     7621 ctccacacta gatgaaaact ttgtttctaa gttgtggcaa gcagataaat tgctctatga
     7681 ttggacggtc aacgatgtaa atagcattgc aaaatctttc cgcttgaatg ttgacggtat
     7741 cataacggac gatgttcaac tggtacaaag ttccattaaa gagctaaaag acaatccaaa
     7801 atatacagac ttactcctta ataaagcctt tgatttcttt aattttacat aaaatagccc
     7861 cctcttagca atgaactagg agggggtgag ttttttgaga tttgttttaa aacggcattt
     7921 tacctgcaaa ggcacctaat tttttcttag ttgcggcatc aatttctacg agggcagcgt
     7981 tgatagcttg ggttgtcatg tcagataaag tttctaagtc ttctgggtca acaacagctt
     8041 cttggaagtc gattttgacg acttttttgt cacctgtaag agttgcgacc acgagatctt
     8101 gagcggattt gccaacaaat tctgtcgcca caagctcggc ttgccctttt tccatttgtt
     8161 tttgcaattt ttgtgcttgt ttcatcattg attgcatatt catcattgtt ttggttctcc
     8221 ttaattttca aacattaaca tcttatttta ccatatctgg cacatctaag ctagagtttg
     8281 ctaggtcaat ggtcaaatga tagtcggtat tatcgcggac ggtgtgctca aagtcggttg
     8341 tgtagaggac aaggcgaagt gtatcgccta ttttcatttt gtaaatggtt ggttgcaatt
     8401 caaaagaaaa ttctaaccat tggtctggtg tgacttcttc aactgttagc aaatcgttgc
     8461 ggttttgcag attgagaaat ccttttgtca caacgcgatg cggtgtctct ttgaaaggta
     8521 attccattaa atgatccagc atataaacgc gaccattgtc catgactttt ggtgtaagga
     8581 cgccaggaat tggggtgagg cgtttagctt gcccaagatc taatagctgt gcagaaatca
     8641 agcctttatc ggtactggat tttaggcgca gattgagctt agcgggaccg ttaaggaaaa
     8701 ggtctttttc taaggtgaag tcaacggtca cttgattgac ttttccgtca aagagttcat
     8761 ttttgaaggt ttgataggtc ttgctgaaac gcttgtagtc tgtatcagag taagcatttt
     8821 gaatatcttg agtagtacta cctagattga aatgagtgta gtgctcttga ttgccgaaat
     8881 tctttagtga cagccagctt tgtgcttgac tattgtcttg ccagatcaca gttggcaatt
     8941 caaagtggga attgtagccc agcagtttct tgctgagaag tgcattcata gattcacgaa
     9001 agtcaatgga ttgccaattg ttcatgtaaa tgtgagcgcc gttgtggaaa aataaatgtt
     9061 ttttgatgtc ttgtggcagg gcgtggaaca tgttgtacac attgagcggc ttgacattcc
     9121 agtcttggga gccatgagtg aagacgactt cggctttgac cttgtgtgcg tgaatcagat
     9181 agttgcggtc atgccaaaat tgattataat cacccgtttc gcgctccaag tttgctttta
     9241 atgttttgag gctcttttga tactcgacat tgtgacgaag acgttcgccc gctagaagat
     9301 tgcgtgagta agttaattct gtcaaagagt caaaatcttc accgggatag ccaccggggc
     9361 tcgtcactaa gccattttca cgatagtaat tgtaccaaga agaaattcca gcttcagcaa
     9421 taatgacctc aagaccatct acgccagtcg tagccagtcc atttgacaag gttccaaggt
     9481 aagaaattcc tgttgtagca acctttccat tggaccaagt ggctttgatt tctcgctgtc
     9541 tggtatggtc tgtgaacgca cggcaacgac cgttgagcca atcaataacg tttttatagg
     9601 cttcaatttg ataataatct ccgctggtca tgaggccttc agagtccttg gttcccacac
     9661 ccgatacata tagattagca aaaccgcgtg aaagcaaata atcattgagc gtgtaagtac
     9721 cgatatgacc gagtgtttct tctgattgct ccaccaatac tgcttggcct tgtggttcaa
     9781 ccaagcaaac ttcagagtca tggatggtga ttttttcggt ctctttttta accaaattca
     9841 cattcatgtt ataaagtgct ttgtcgctgg ctttgtcgtt ggttccttgg tgataagggc
     9901 tagcagtcat gacagcagga atttgtccat caaaatgagg acgaatgatg ctgaccttaa
     9961 tcaaatcagg cagctcatct tcatcggtat ccacacgcga ttccacatag accacttcgc
    10021 ggatagcatt atggctagta aaggtcgcaa gacttttacc attgaaatag tggtaggtat
    10081 tgtcttcagg gatcaagccg tcgctcacta gtttatcaat caagagattg ccgtttttgg
    10141 tgcgtgtgtt gagcaattga tagagatttt cgagtagatt tccataggta atgggaaagt
    10201 ttatgtcctt gcggaatgtt tttacttcat caaagtcaac aaagggcaca aattccagta
    10261 attgaaaagc aatcgtataa aaaatctctg ctgtcaattc ttgcttggac gtaaaaaagc
    10321 tgagtaagtc tgtatttgaa ttggcaacca aagactttaa agcatagtct gtatttttat
    10381 aattaaaaaa agttctacgt acaaaagttt ctaaattttc tttatcagaa tgctctgggc
    10441 ggaaagaaaa tccaatgctt tccatttcag ctaggatttt ttcgcttgtt tctggtgtat
    10501 aactatactg gttgtaacgc atatttttac tcctttttta cattttgtca aaaaataacc
    10561 tttacattat acattgtaac tgataaaata agatttgtct aaaaattttt taattaaaga
    10621 ggagaacaaa aatggatgtc acatggattg tgaaatatat tacagagttc cttggaacgg
    10681 caattctcat tattttgggg aacggggctg ttgccaacgt tgaattaaag ggaaccaaag
    10741 gtcatcaaag cggctggtta gtcattgcag ttggttatgg tatgggggtt atgattcctg
    10801 ctcttatgtt tggaaatgta tcagggaatc atatcaatcc tgcattcaca ctaggacttg
    10861 cgattagcgg atacttccct tgggcacaag ttgcgcctta cattattgca caattattgg
    10921 gagcgatatt tggacaagcg ttagtagtag caagtcaccg cccttactat ttgcaaacaa
    10981 caaatcctaa tgcgattttg ggatcattct caactattgt aaatacggat gacggaagca
    11041 agaaatcaca tgctgcttct atgataaatg gttttgtcaa tgaatttatt ggttcattta
    11101 tcttgttctt tgcagcaatg gctatgacca aaaactattt tggtgcagaa gttgttaaat
    11161 atgctgctac tcgtggagtg gatgctactc aaatccaagg aaaagttgca attggttctc
    11221 acatcaatgc cggacttgct gttgcccact tagcacttgg tttccttgtc atggcattgg
    11281 taacgtcact tggtggtcct acaggtccag gtttgaaccc tgcacgtgac ttaggtccgc
    11341 gtattcttca tttccttctt ccaaaatcag ttcttggtaa gcacaaagga gattcaaaat
    11401 ggtggtatgc ttgggtgcca gtcgtatctc caattcttgc cggtattgct gcagtagcac
    11461 tttacaagat aatttatgga taagttgtca aaaaagaaac ggttcgttac gagccgtttt
    11521 ttgataacga agagataaga ttgagcgaaa aaatagataa gtgactagac gcttgctaag
    11581 ataaaatact atactaaaga gtaaggataa caacagtaat gggagtgaga cagcaaaact
    11641 gatttttttc aaagtagcaa tttttgtctc attcctacct tttatttggg agagatgaaa
    11701 tggaattaga taaactaagt gggagacgga ctctattgtt cggtattttg gcgattcttt
    11761 ttggcgttat tattattgca aacggtgttg attttgcaaa atttgcccta gatttattgg
    11821 tcatttactt tttatttgtt ggagttatca atcttttttt ccgtttctta gtgaagcaaa
    11881 atcgtatcag tcttggttct gccctcctcc atgttttggt agggctggtt gttggctttc
    11941 ttaaccgtgc cagcaatctg ccagtcaata ttgtcattat tatattgggc tgttatcagc
    12001 tgtgtacagc ggcaatctat ggtattacat atcttcttta tcggcagaat aagttaaaag
    12061 gtggttttcg ttatcttttt gatacctttc tctatggtgg gattggcctg acacctgtct
    12121 tttctcccag catggacggt aggatgcaat ttttgattat tggtatttat ctgatattac
    12181 taggcttttc taacgttcga gacggtctta tgttcaacac cgatgtggag aaaaaacaac
    12241 ttcgacgccg tattcggatt aacctgccta tcattatcgc tgcctttttc ccagcagagc
    12301 aactgaatcg ttttaatcgt ttttggcaag gtgaaaaaag gaaaccacaa aaggtttata
    12361 gtcgtgtccg agacgaggaa aagcccattg acttagaggt gctgatccat acgtcagacc
    12421 agaatctttt tgggatgatt gggcatgttg atatttgcta taaaggaaaa gttgtttcct
    12481 atggtagtta tgatattttt tcagagcgtt tattcggcac gattggagat ggtgtcttgt
    12541 ttaaagtaga taaagatgct tatattgact tgtgcaaaga agaaagcaaa aaaaccttgt
    12601 ttggctatgg tttatctctg actgatgaac agaagcgcgc tgtggagaag cggttggctg
    12661 agattgatga gttgctggaa gtctggaatc caccagcaga tttgaaagat ggtaagcgca
    12721 cgtacgctta taagttgaag catgagttgg gtggtcgttt atataagttt aaaacaagtc
    12781 gttttaagac ttattttatc ttgtctacca attgctgtct gctagccgat agcattatcg
    12841 gacaggctgg aacagccatt ttagatatgc gtgggattat tgcgccggga acttatcagt
    12901 cttaccttca atatgaattt gagtcggcaa atgagctggt agtggcacaa aatatttatc
    12961 agtaatagca caatttgttc tatttttaca taaatatttg taaaatacac aaaaattatt
    13021 taaaatagaa aggcttggag gaatttatgt gttcaacaaa taaaagtgta aatacgatac
    13081 cagtattaaa aatcaataat cgaaaaaaca atctcgcatt ttattgtcaa actttaggaa
    13141 tgaaaaattt gctagaggaa ggagcttttg tcagccttgg agatcagaca aaagttgaaa
    13201 aattgcagct agaggagtcg cccagtatgc gcactcgcaa agttgttggg actaagaaat
    13261 tagcgaaaat tgtcatcaaa gtagccaatc cacgagaaat tgaagcactt ttagcgcgtg
    13321 gcagcaaggt agattatctt taccaaggtg ataatggcta tgcttttgaa gcaacttcac
    13381 cagaaggaga tagatttttg ctgcatagcg agaaagactg gacagcctta cagagagtga
    13441 tgatagcacc agcatttgcg ccattagagg attttgttgg gctcagtcaa tttactatag
    13501 agcagattca tatcaatgct ccagataagg aaaaagcagt cactttttat caggaatggc
    13561 taggaaatca gtctattcta acattctcac aagcaagcgg accagatttg ctgacggaga
    13621 gtactcaaac ttgggatttg gcaatggtta aatttacagt tgagcaattt gatgtggaag
    13681 cattacgtga tttatttcaa ggaagagaaa attttatacc taaatcgggc aaatttttcc
    13741 tgaccaaaga tgagagccaa attgaagctt ggattgaagc ggtatgagtt caagcaagat
    13801 actctcaaaa gtcggagaac agatagcaca acaaatctat cctggagcta gcttagcttt
    13861 gtatactcgt ggagagtggc aagaatatta tcttggtgag agcaatcctg agcgaggtga
    13921 gaagactcaa gcaggactgg tctatgactt agcgagtgtc agcaaggttg tgggtgtcgg
    13981 aacgattttg gctgttctat tccatgagga aaaactagat ttagatgcac cgctaacaca
    14041 atattatccc gcttttcatg acaattctgt cacggtaggt cagctggctg ctcacacatc
    14101 agggctagat ccctttatcc ccaatcgaga tgcactcaat gcggtcgaat tgaaagaggc
    14161 gctaaatcat ttgaaagtgc ttgataacaa gcattttcgt tatactgatg taaatttttt
    14221 gttgctaggt tttatggtag aagaaatttt tcattcttct ttgagtgaca tttttgagcg
    14281 gaaaattttt cagtcttggg gtatgaaaga aacaacgttt ggacctgttg cgcaagcggt
    14341 gccaacggtt cgcggtgtga aggcgggagt tgtacatgac cccaaagcgc atgtgttggg
    14401 cagacatgct ggtagtgcag gcttgttttc gacagttcgg gatttggagc tctttttgga
    14461 gcattattta caggatgact ttgcagcaac tttgacaaaa aatttctcaa aggagattgg
    14521 aaaaacacgc agtcttgctt gggatttaga caaagagtgg ttgcagcaca caggctatac
    14581 tggaacgttt attatgttta atcgtttaca gcagaaagcg gtcatcttcc tttccaaccg
    14641 aacgtatgag aaagacgaac gtgcacaatg gattttagac cgcaatgagc tcatggattt
    14701 gattaaacaa aatctgtaaa atgaagacag ttaggataag agctggattt cctgctcttt
    14761 tcgctgtttt aaaagttgaa ataaattagt ttggaatata aaaggaattg actactaacg
    14821 atcgcttttt tctatgaatt atattaaaat aatagatgaa gtattgtgat gtagagagaa
    14881 tatgacaaaa aaagtaggtg tcggtcgggc acatagtaag attattttga taggggagca
    14941 tgccgttgtc tatggctacc ctgctttggc tctaccttta actaatattg aagtgacttg
    15001 tcgcattttg ccgtcagatc atgcgtggat tttgtatgaa gaagatactc tttctatggc
    15061 ggtttttgct tctttggaat ttctaggggt gcaagaggct tatattcgct gtgagattga
    15121 gtccatggtg cctgaaaaac gcggaatggg ttcttctgcg gcagtgagca ttgctgcgat
    15181 tcgagctgtt tttgattatt atgaacagga gttggatagg gaaactctgg agattttagc
    15241 aaatcgggca gagatgattg cccacatgaa tccgagtggt ttggatgcta agacttgctt
    15301 gagcgatcat gctattaaat ttattaaaaa tgttggtttt tcagagtttg agacgaatct
    15361 tggagcttat cttttgattg cagacacagg gatttatgga catacacgag aagcgattca
    15421 aaaggtggaa agtattggaa gaagggcttt gccacatttg catcagcttg gaaaattaac
    15481 caatgaagtt gaagaagctt tgaaagtaaa agatttagag agaatcggga tagccatgtc
    15541 agaagctcac ctcagcttaa aaaatctaga cgtgagttgc cctgaagccg attggcttgt
    15601 tgctacagcg caagaaaatg gagcacttgg tgcgaaaatg agtggtggtg gtctaggtgg
    15661 ctgcattatc gctctagtgg cgagcaaaga aaaggctgtc agtttggctg atttattgag
    15721 ggagaaagga gcggtaaaca catggatcga aagtctgtaa aggtgcggtc ttatgccaat
    15781 attgccatta tcaaatattg gggtaagaaa gatactgtca agataattcc tgcaacgagc
    15841 agtatttctt tgaccttgga aaatatgtac acagaaacaa ctctgtctag cttaccagcg
    15901 agtgctcagt cagatgaatt ttatatcaat ggtgttctgc aagatcaagc tgaacataaa
    15961 aaaatgcgca atattgtaga tcgttttcgc cctcaaggag ctggatttgt acgcattgat
    16021 acaaaaaata atatgccgac agcagcgggg ctttcatcta gttcaagcgg tttgtctgcg
    16081 ctcgttaagg cttgtaatga cttttttgaa ttgcacttgt ccacaaaaga gcaagcacaa
    16141 aaagcaaaat tagcttctgg gtcttcctca cggagttttt atggaccgat tgcagcttgg
    16201 gacaaggata gcggagagat ttatccagta aagacagatt tgaaattagc gatgataatg
    16261 ctggttttgt atgatcataa aaagccgatt tcaagtcgtg agggaatgaa acgctgtgca
    16321 gaaacctcca cgacatttag tgattgggtg agacagtccg aagaagatta taaagccatg
    16381 ttgacttatt tgtctaacaa tgattttgct aaggtgggag aattaacaga aaaaaatgcg
    16441 cttgccatgc atgctaccac tcagacagca acgccagcgt tttcttacct gaccgaaaaa
    16501 agctatgaag caatggactt catcaaacaa ttacgcagtc aaggagagca ctgctatttc
    16561 accatggatg caggaccaaa tgtaaaggtt ttgtgtttag aagaagattt ggaacattta
    16621 gtaccaatat ttgctgaaag atatcatctc attgtttcta aaacgaagga attaccagat
    16681 gactaagaca gtaagaacat gtgggaaatt atatttagca ggagaatatt ctgtcttgac
    16741 ggcagggcaa ggagcgattc tgaaaaatat tccgatttat atgacgggaa aaattcattt
    16801 ttctgaacgt tatcagttgt tttcagatat gtttgaccat actgtggatt tgacacctga
    16861 tgatgagtac agtctcattc aggatacggt tgctgttatg aatgagtttt tacaaattcg
    16921 attcatttca ctacgtccct ttttcttaac cattactgga aaaatggagc aagatggaaa
    16981 aaaatttggt cttggctcta gtgggagtgt cgtagtttta accatacgag caataacagc
    17041 cttgtatggt ctggcgttat ctgctgagga aacctttaag ctggcagcct atgtccttct
    17101 taaacgtggg gacaatggct caatgggaga tgtggcttgt atcgcttatg aggacttgat
    17161 ttattaccaa tcttttaatc gaaaaaaaat agcagagcag atcaatgagc ttcctttaga
    17221 aaagatagtg acacaagatt ggggatacat tatccggaca atccatccac agcttccatg
    17281 tgatttcctc gtgggctgga cgagagaacc agctatttct agcgttctca tcaatcaagt
    17341 caaagcaaaa atctcatcaa gctttttaac acaaacgcaa gaagaagtcc ttcgactgga
    17401 gaaagcgttg tttgttggtg agaaagaaat tgtgaagcaa agtctagaaa aagttagttg
    17461 cctcctgctg caactgagcc ctgctattta taatgaaaaa ttgagagctt taaaaaggtc
    17521 tagtcaagga ttggactgtg tggcaaaaag cagcggtgct ggcggtggtg attgtggcat
    17581 agccttgtct tttgattccg aagccagtca aatcttagtg gagcgttggc aagcggcagg
    17641 aatcgaggtt ttatataagg agaggtggga tagatgagcc gaaatcgtaa agatgaacac
    17701 ataagatatg cgcttgagta cgattcgcct tataatagtt ttgatgacat ggagcttatt
    17761 cattgctcgc ttcctaagta tgatttgggc gagattgatt tgacgacgca gtttgcaggc
    17821 agagattggg aatttccgtt ttacatcaat gctatgacag gtggaagtga gaaagggaaa
    17881 gacatcaatc agcgcttggc acaagttgca gaagcttgcg gtattctttt tgtcacagga
    17941 tcttacagcg ctgccttgaa taacccaaca gatgattctt atgctgtcag caaaggcaag
    18001 tccgacctgc tccttgcaac gaatattgga gtggataagc cgtattcctt agggcagcag
    18061 gcaatcacag accttcaccc tctttttttg caagtgcatg tcaatctcat acaagaattg
    18121 ctcatgccag aaggagaacg ttcttttaaa acttggcgag cacatttaaa agactatgca
    18181 gagcaaagtt cagttccagt agtattgaaa gaggttggct ttggtatgga tttggcaacg
    18241 atcgaaattg cttatgacct cggtattcga acggttgatc tttctggtcg tggcggaacg
    18301 agcttcgctt atattgaaaa cagacgcggc ggcaatcgag actatctcaa tgattgggga
    18361 caatctacgc ttcaagcctt actaaatgct cagccgatga tggataaaat ggatattttg
    18421 gtgagtggtg gcgtacggca gccgcttgat atggtgaagg cttttgtgtt aggagctaag
    18481 gctgtaggac tttcacgcac catgttagaa ttgattgaaa cgcattcggt ggatgaagtc
    18541 atcacgattg taaacggttg gaaagaagat ttgcgcttga ttatgtgtgc acttggttgc
    18601 caaaatttga gagagctaag acaagtgcct tatcttttgt atggacgttt gcgagaagca
    18661 caaggtcaac taaataaaga aatccgatga gttttttcac ttatcggatt ctttttttct
    18721 atgatttttg acgaatgttt tctaaaattt cttgtgctct tttgagacta aaatgtttct
    18781 cagaaacgag ctgagaaatc agaggagcga tttctgtatc cttagctcct gctaaaagag
    18841 ctagagattt ggcttgtagc ttcatgtgac cgtgctgaat gccggtgctg accagcgctt
    18901 ttagagccgc aaaattttgc gctaagccga tagacgcaat aatactggcg aactcttttg
    18961 cggttggttg ttttagcaaa tcgaagctaa cttccaccgt aggattgagc ccaatggaac
    19021 ccccttttgt agcaataggg agcgggagag taatctctcc gcagagcgtt tgagtggctt
    19081 ccttgattga ccaagtagtc aatccttgat aggaaccatt tctactagca taggtatgcg
    19141 cgcctgcttc aatcgcccgc cagtcatttc ctgtcgctaa tacgacagca tcaattccat
    19201 tgaaaatgcc tttgttgtgg gtgctggcgc gataaggatc ttgcttggca aattggcttg
    19261 ctaacactat tttcttagca atatcaaggg cttctgactt atttcggtcg agaaaacgga
    19321 tatcaatttc acaggtggca gttactaagg cttccgttgc ataatttgat agaattgcca
    19381 tcaagctttc accgccagtc aactcttcta atggtgtttt caacgcttct agcatggtat
    19441 tgaggatatt ggctcccata gcttcttggg tgtcaactgt tagataaacg actaaaaatt
    19501 cagcttcgcc atttagccat tctacacgta aatcgcatgc gccgccaccg cggttgacaa
    19561 tcgatgggtg tgcttgattg gccaattcta ataactcttg cttgtggttt tggatatttt
    19621 ttatagctac ttcaatattt gctacttgat agagagcaac ttgtccaatc atttggcgat
    19681 tgtgaatagt cgttttgaag cccccagagc gcttaataat ttttgctgca aagctggcag
    19741 ccgcaacgac agagggctct tctgttacga aaggtacttg ataaacttcc tcgtctacca
    19801 caacatcagg aacgaaagag tagggcagag caaatgtcgc cagaacattt tcgctcattt
    19861 ggtcggctgt tgagagaggg agcatgtgat tatgctcaag gtttgtttga ttatcctcgt
    19921 ttagtaagtg atagtctttt aaaatttgca aacgttcttg aagcgatttt tttgaaaagc
    19981 ccgtccaact tattttcata ttatttttcc accttgatat atctgcgttg gtgctcaaca
    20041 atttctgcta aagcaaagtc ttgattttca tagttcgtaa agctggccga tccattttca
    20101 tccagacttg cttcttcaaa aaatattttc tcgtaatctg gaatgcttaa aggcgtgcgc
    20161 ttgttgagta tttccatacg attggtttca agctgttgct caaagcctgc tacgagctgc
    20221 ccactaaaga tttctgatac agctccgctt ccgtagctaa agagcgcaat gcggtcacct
    20281 gctttgagtg ttgtactatt ttcaagcagg gaaaggagac ctaaaaagag agaaccagta
    20341 taaatgttac ctactttttg gctgtaaaga atggattgct caaaattttc ttgcagttgt
    20401 gcttgttgct cgcttggcaa actcttatcc ataatctttt tcataccctt taaagctaat
    20461 ttaggataag gcaaatggaa gcaaactgct gcaaaatctt ttaaggacac ttgattgtgc
    20521 ttttggtact ccgcccaagt tgtttttaga ctgtctaaat actgttgtgt agaatacatg
    20581 ccattgacaa acggcgttgt cgaataattt ggccgccaaa agtccataat atctcgtgtt
    20641 tgagcaacat tgtcttcatt aaaactgaga atccgtggat tacttgtgat gagcatagcc
    20701 actgctccag ctccttgtgt tggctctcct ggtgtctcaa taccgtattt ggcaatatcg
    20761 cttgcaatga ccaacacctt tgagttaggg tgtttttcga cgtgcaactt cgcataatct
    20821 agtgcagcag tagcgctata gcaagcctct ttcatttcaa aactacgcgc aaaaggctga
    20881 attccgagta gaccatgaac aaaaacagca gaagccttac tttggtcaat cccagattcg
    20941 ctggctacga tgaccatgtc aatagcttgc ttatcttctt cgttcaaaat agacgctgct
    21001 gcactcgctc ccatggttac aatatcctct gtgacagggg cgatactaat ttcttttaat
    21061 aaaagtccct tacttagttt ttctgggtca atgttacgtg cggctgctaa attttctaat
    21121 tttaatacat aattggctgt tgcaaagcca attttatcaa ttccaatgtt catcattacc
    21181 tctatatatt tttcggtttg ataccaaact tattctattc cattttatca taattaaagt
    21241 ggaaactgag aaaaaagcct tcttacgaaa agaaagactt gggacatttt caggagttat
    21301 gtcgaattat gaggagcgat gcttttgcag ataatggtag agtctgagca ccaccgtacc
    21361 acttgccatt ccaattgaaa tgaccaaggc taaaatcacc accaaggtag cattaatcat
    21421 agcatgacta taatctccag tgacaaaaaa ggccgttgta cgataagaaa gatagcccgg
    21481 aaccaatgga gctaaaatgg ctaagataaa gacgacagca ggggttttat aaagaatgct
    21541 caaaacttga ctaatgcaag atccgataat agctgcgata aacgtagcaa taatcacatt
    21601 tgttggacct tttaatacat aatacaaaag ccagatgaac attccaagga ttcctcctgg
    21661 aatgagcatt cttttttgaa tatttaaaac gattaagaac attacaattg caagaaaact
    21721 tgctgcagct tgtagtaaga cagtcaatgg cttcaccttt tatttcatta agacgagagc
    21781 tacggaagtg ccagctccga gtgccaaagt gatcaacagc gtttcaaaga ttttgctcat
    21841 tccggagttg agatgattgg tcatcaaatc acgcacggca ttggtcagag caataccggg
    21901 aacaaaaggc atgacagcac cagcgatgat taagtccgca ctggaaggaa agccagaata
    21961 gcgcgcccag atctgtgcca gcagaccaaa aataaaagct ccggcaaaag ctgtgacaaa
    22021 aggaatgcgc acgtatttat tgaccgaaag agaaaaggca aagccaaaga aggtcgcaag
    22081 agcagcgccg agcgcatcat agagattgcc accaaacatt atagagaaaa aaggggcact
    22141 aatagtagca gcaaatgtca gttgcctgtt tgtgtaaggt gtctttttct tttttagctg
    22201 agttaatttc tcaaaagcat cttcaagact gatgtccccg ctaaccagtt cacgcgatac
    22261 ttgattgaca tcgcacactt tttcgatatt gtaatttgaa tgagtaatgc gtttcatacg
    22321 cgaaatattg gtgttttcaa ttgaaaagaa aatggcaact ggcattgcga gtgcattaca
    22381 atccataatt ccttgagaat gagcaatccg aatcatggta tcttcaaccc gataaatttc
    22441 agaaccactt tgaagcagaa gcgtacctgc taacatcagg acatcaacgg ttagattaaa
    22501 tttgtcttcc ctttctacat cttttttctc caccattttt acaccctttt cttttaatta
    22561 acaatacctc tattatagca taaaaaagaa gaaaaccagc tggaatttcc aactggtttt
    22621 tgagaataga attgaattag ctaagggcat catccattga aagcacttcg tggaagacac
    22681 gttgagtcaa ttcagttttt tgttctttag taaggtattt ggtattgaca cagtaacctg
    22741 agatacgaac gataacatct tcaccattca taatcttatc atagacatcc ttcaagtcca
    22801 taacgttcaa gttgacgtgc tgtcctccat tttcaaagta accatcaaga atcgttacca
    22861 agttatctac ttgttcttcg cgcgttttac caagagcacg aggtgaaact tgtgtcgtca
    22921 atgaaatacc gtctgctgca taaccaaagt caaggctagc tagtgagttg agattttgca
    22981 accaaccacc acgagctttg ttagaagggt ttgcacctgg tgagaagaat tccaatttag
    23041 acaagttaac actgccgtct tcattgagat aaaccccttt gtgaactgga gagttaccag
    23101 tttgtttaga gtaagcaacg tttgaagtga tcgtcaagag tgatacagtt gcttcagcgt
    23161 tcttgtaaag tctgtggcta cgaagacgag ttgtgtaggc ttcaatcaac cattcggcta
    23221 attcgtttga gcgaggatcg tcttcacccc aacgtggata ttcgccagta gtttcgtagt
    23281 cgtagatata accattttcg tcacggattg gtttgactgt cgcatactta atagctgaca
    23341 atgtatcaac tgtattggca aatccacaga taccaaatcc catattagca cgttgatggg
    23401 ttggtaagaa ggccatttga acagcttcgt agttgtactt gtctgtcatg tagtgaatga
    23461 tgttcaaagc atctacataa gtgtctgtca accaatcaag tgatttttca aagtttgcct
    23521 taacagattc aaattcaagt acttcgtcgc tgatagggtc aatatcaaat actttgtaat
    23581 ctttatgaac atcatcgtaa ccaccgttaa gacctgtaag aagagctttt aacacgttta
    23641 cacgagcacc gaagtactgg atgttgtgac gttggtcttc gttttctggg tcaagtggtg
    23701 atacacagca tgaaatacaa ctcatttcac catagccatc tttcgccatt gttgttacac
    23761 cttcgtattg gatagaagag tgtttgtgac tcatgtgcat gcagtaatga cggaatgagt
    23821 aaggaagttt atctgtccaa agaactgtca agtttggctc tggtgagtta ccgatattgt
    23881 caagtgtatt caagaaacgg tagtccattt ttgtcacacg gtgacgacca tcatttccca
    23941 tacctgccat agatgttgtg atgaaggttg ggtcacctga gtagagttga tcgtatgctt
    24001 ttgtacgagc aaattttaca gtacgaagtt tcaagacgaa atcatcaaca aattcttgga
    24061 tttctgattc tgtgaaagta ccacgagcaa ggtcgcgttc tgcataaatg tcaagaacga
    24121 ttggcacacg tccaagagaa gtagcagcac catttacgac acggcagaca gccatgaaag
    24181 cgacattcac ccattggata gcttctttta cattcattgc aggtctacga acatcaagtc
    24241 cgtaaaggtc acccaggcgg acaacttctt tcaatgattg gtattgaagg ttgacttctt
    24301 cgcgaagacg aatagtttct tcatcaatgt ctgtcaaagc attccaatct tcgacttttt
    24361 ctgccatcaa gtaatctgca ccgtaaagag caagacgtgc gtaaacacca atgatacgtc
    24421 cacgtgaata agcatctggc aaacctgtta cagtgtgtgc gtgacgtgca cgacggatat
    24481 ttgttgtgta ggcacggaaa ataccgtcat ttacagttgt tacgtatttt gtgaagattt
    24541 catgcatctt aggatctggt tcatagccat gttccttcaa agcagtttcc gccatacgga
    24601 taccaccttt tggcatgaag tttaatttga acaattcatc attttggata ccataaatca
    24661 attcattatc tttgtcaatg tatccagctg gaatatcagc gattgaagta gcacgtgtat
    24721 ccattgggaa acgtgtttct tcataatgtg cttttgtatc ttcgataatt tttttaatgt
    24781 gaagagagcg ttcagttgga ccagctaaga aactttcatc tccgtcataa ggagtgtagt
    24841 ttgcctgtac aaaacgagat acgctagctt tttcgcgcca atcttcccct ttgaagcctt
    24901 cccaggcttt gtcaaaaaca tcctgtgctt cgacaacagt tttaacaacc atgttttttt
    24961 cctcttgtat ctttctagta acacaaatct gttacattta taaaacaagt atatcatata
    25021 gtaatcgttt ccacaaatga aacctggcca taaaagcact ttcttttata atacagatta
    25081 aaaaatcagc gtaaattgta ttatattttt gaaaaaatca gcatattttc aaatattttg
    25141 gaaaaaatga taaaaattgt ataatggagg aaagaaaaga gtcaagaaag gagctgtatt
    25201 gatgttaatt tttcccttaa tcaatgatac gtctcggaaa atcattcaca ttgatatgga
    25261 tgcctttttt gcctccgtag aagaaagaga caatccagca ctaaaaggca agtcggttat
    25321 catcggagct gaccctcgct tgacaggcgg acgaggcgtt gtttcgactt gcaattatga
    25381 ggcacgaaag tttggtgttc actcagccat gagctccaaa gaagcttatg agcgttgtcc
    25441 acaggcgatt ttcatttcgg gaaattatga gaaatatcag gcagtcagtc agcaaattcg
    25501 agccattttt aaacgatata cagatgtgat tgagccaatc agtattgatg aagcctatct
    25561 ggatgtgacc aaaaataagt taggtatgaa atctgctgtc aagatagcca agctaatcca
    25621 gcatgagatt tggacagagc ttcatttgac cagttctgct ggtgtgtcct acaataaatt
    25681 tttggcaaaa atagctagtg actatgaaaa acctcacggt ttgacggtta ttttgccaga
    25741 agaagcagaa gcttttctct ctcaaatgga tgtggcaaag ttttacggtg ttggaaaaaa
    25801 gacggtggaa aagctgcatg atatgggcgt ttacatagga gcagatttat tagaaattcc
    25861 tgagatgacc ttgattgact tgtttggccg atttggattt gacctttatc gcaaggcaag
    25921 aggaatcagc aattcaccag taaaagtcaa ccgtattcgt aagtctatcg gcaaggaaag
    25981 aacttatggg aaattgctcc ataacgaaga cgacataaaa aaggagctga cccttttatc
    26041 acaaaaggta gctcgtagtt taaaaaagca tggaaaatct ggtaggacga ttgttctgaa
    26101 gattcgctat gcggattttt caacattgac aaaaaggcag agcttagcga caagaacgca
    26161 agatgcggag cagattgagc gcattgcaca tgagatttat gatagcttgg acgagcagac
    26221 aaaaggtgtg cgtcttttag gagtgatagt gacaggattt gggatgtaaa aaagtttggg
    26281 atggggagtt ccaaactttt tgggctctat aatttctgta atgggtaaca ctactgcaga
    26341 gattatggag ttatttttct accatttgtc aagcaattca atgtttttca gtcaaagaat
    26401 tgatgattga tttgatttta atagtttatc
//
