LOCUS       NZ_SPGD01000002        20903 bp    DNA     linear   CON 20-MAY-2024
DEFINITION  Streptococcus anginosus strain 1001175st1_H11
            NODE_2_length_153302_cov_81.0813, whole genome shotgun sequence.
ACCESSION   NZ_SPGD01000002
VERSION     NZ_SPGD01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus anginosus
  ORGANISM  Streptococcus anginosus
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus; Streptococcus anginosus group.
REFERENCE   1  (bases 1 to 153302)
  AUTHORS   Yang,C., Faith,J. and Aggarwala,V.
  TITLE     Strain-level differences in gut microbiome composition determine
            fecal IgA levels and are modifiable by gut microbiota manipulation
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 153302)
  AUTHORS   Yang,C., Faith,J. and Aggarwala,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAR-2019) Genetics and Genomic Sciences, Icahn School
            of Medicine at Mount Sinai, 1470 Madison Ave, New York, NY 10029,
            USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.10.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 85.9707156971x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005844435.1-RS_2024_05_20
            Annotation Date                   :: 05/20/2024 01:50:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,133
            CDSs (total)                      :: 2,088
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 73 of 151
            Pseudo Genes (incomplete)         :: 73 of 151
            Pseudo Genes (internal stop)      :: 52 of 151
            Pseudo Genes (multiple problems)  :: 40 of 151
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:21:34
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 126532
            Orig. end                         :: 147435
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            SPGD01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20903
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20903
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20903
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10903](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10903)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    971..985
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     gene            complement(1162..1437)
                     /locus_tag="FGQ50_RS01665"
     CDS             complement(1162..1437)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0030261 - chromosome condensation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1132: DNA-binding
                     protein HU 1"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /locus_tag="FGQ50_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HU family DNA-binding protein"
                     /protein_id="WP_003023726.1"
                     /transl_table=11
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFAAVTEYLAAGEKVQL
                     IGFGNFEVRERAARKGRNPQTGAEITIAASKVPAFKAGKALKDAVK"
     gene            complement(1566..2399)
                     /locus_tag="FGQ50_RS01670"
     CDS             complement(1566..2399)
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002925543.1"
                     /locus_tag="FGQ50_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DegV family protein"
                     /protein_id="WP_024052826.1"
                     /transl_table=11
                     /translation="MTKIKIVTDSSITIEPQVVEDLEITIVPLSVMVDGVVYSDADLKE
                     GEFLRLMQSSKNLPKTSQPPVGVFAEIFETLGETADKIISIHMSHALSGTVEAARQGAT
                     LANVDVTVIDSSFTDQALKFQVVEAAKLAKEGADFDAILARIEEVREKTELYIGVSTLE
                     NLVKGGRISRVTGLLSSLLNIRVVMQMKNNELQPIVKGRGVKTFKKWVNDLVESLKDKK
                     VAEIGISYAGTAELANEMKQILQPCVEKTISVLKTGSIIQTHTGENAWAVLVRYE"
     misc_feature    complement(2537..2551)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 25.98"
                     /tool="antismash"
     gene            2629..3582
                     /locus_tag="FGQ50_RS01675"
     CDS             2629..3582
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006269745.1"
                     /locus_tag="FGQ50_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_024052827.1"
                     /transl_table=11
                     /translation="MKQTKFLGILCLALVMISITVGSGHFSWWQLLHGDKQTGLLFLES
                     RLPRTVSILLAGSSMSIAGLLMQTVTQNHFAAPSTVGTVEAAKFGMLLSLFFFPSATLA
                     QKMLFAFVSAIFFTIIFIRLIRKFSFKEKWLLPLVGIIYSGVISAAGEIIAYRFELVQS
                     MTSWTQGSFSMIQKHQYEWLFLSLIILIAVWKLSATFTIMNLGEDASHNLGISFYQMEG
                     MTLFLIALTTSVTMITVGSLPFIGVIVPNIIRKFYGDHITRIKGLTALTGSCLILICDI
                     VARLVIRPYEVSVSLILGILGSLAFVYLLWRGAAHE"
     gene            3575..4537
                     /locus_tag="FGQ50_RS01680"
     CDS             3575..4537
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041111.1"
                     /locus_tag="FGQ50_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_024052828.1"
                     /transl_table=11
                     /translation="MNKMKSQTRNRLLLLLLLASLSGLLYLMPMEYPLTGFIMKLRSQK
                     LLAYLLVAIAGGLATISFQTITENRFLTPSILGMESLYVFMQTIYLFFASKFICNTGHP
                     LLEFILVLLIQCGFFFCLQPALKKLLQQGFVFILLICMALGTLFRSASTFLQVLMDPNE
                     YDKLQTKLFPSFQRINMDILSVAAIIIGLAGLYLLKKNAILNVFHLDKKTATILGVEVE
                     KEQKKILWAIVLLTSTTTALVGPMMFFGFMMSNLAYLLIKEYQHKWLFSVAILLGFLSL
                     TTGQMLVERVFQLQINVSMVIELVGGLFFFYLLAKEVKR"
     gene            4539..5291
                     /locus_tag="FGQ50_RS01685"
     CDS             4539..5291
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268271.1"
                     /locus_tag="FGQ50_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_024052829.1"
                     /transl_table=11
                     /translation="MQLKNVGKSFGNQAILEDIQLNISPSKFTAFIGPNGAGKSTLLSI
                     MSRLLKKDQGFLSIKGKEIEAWNSKELAKELTILKQKINYQSKLTVEELVSFGRFPYSQ
                     DRLTKEDFKKVEQALEYLDIADLRERFIDTLSGGQLQRVFIAMVLTQDTDFIFLDEPLN
                     NLDIKQSISMMKILRSLVDDLGKTIIIVIHDINIASQYVDEIVAFKDGKVFYQGTTNQV
                     MRKEILDPLYEMDITLGEINGKKVCIYL"
     gene            5315..6289
                     /locus_tag="FGQ50_RS01690"
     CDS             5315..6289
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023719.1"
                     /locus_tag="FGQ50_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_138283978.1"
                     /transl_table=11
                     /translation="MKKNTKTLLLSLFAAVAVVLLAACSDNKQSNSKTTNSSSTSSEVT
                     IKTANGDVKVPTNPKKIVTLDLGAADTIRALGKESSIVGMPKKTLPAYLKNLPSSIKNV
                     GSMKEPNMEAIAALKLDLIIASGRTAQYVKKLKEIAPTVLFQTDNKDYWGSTKKNILSL
                     ASIFGEDGTKKAKSELATLDKEIQTVVAANEKSNKNALAMMLNEGAISAFGAKSRFAFL
                     YSTLKFKPTDAKIKESRHGQEVSFESIKQINPDIIFVLNRTLAIGGDNSANKDLLNNSL
                     IQETNAAKNKTIVNLTSDLWYLSGGGLESTKLMIEDVKNVAGK"
     gene            complement(6352..7083)
                     /locus_tag="FGQ50_RS01695"
     CDS             complement(6352..7083)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023717.1"
                     /locus_tag="FGQ50_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_024052831.1"
                     /transl_table=11
                     /translation="MTNYFVIGDVHGKAKMLKELLKKWDGESQLIFLGDLIDRGEDSRA
                     VLECVKSLVDKQGAICISGNHEYMFLTWLDNPESGYAHYRRNGGDTTINSILGRPLDTP
                     VDGVEDAKRVSEEAPDLVYFIRQMPFFVETDNYIFVHAGVDLTLKDWHETSDYQKVWIR
                     EPFHQGLNQTGKIIVFGHTPTFYLFSEMPGTSRLWQTQDQKIGMDGGAVYGGVLHGVLF
                     GNEGILEHHFITNDGFAVEDN"
     gene            complement(7130..8788)
                     /gene="recN"
                     /locus_tag="FGQ50_RS01700"
     CDS             complement(7130..8788)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896130.1"
                     /locus_tag="FGQ50_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DNA repair protein RecN"
                     /protein_id="WP_138283981.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEEISLNFEQGMTVLTGETGAGKSIIIDAMNMM
                     LGSRATTDVIRHGASKAEIEGLFAIEQSKALVEIFEQQGLDMTEELIIRREIFQNGRSV
                     SRINGQMVNLSVLRAVGQHLVDIHGQHDQEELMRPQLHIAMLDEFGADAFFKLKADYQQ
                     TFDQYRQLRKQILTIQKNQEENKARIDMLEYQIAEIEAANLKASEDLALNQERDKLLNH
                     KQIADTLTNAYAMLDDEEFSSLANIRSAMNDMEAIEDYDATYKEIATNLSESYYVLEDV
                     TKRLEDILEDLDFDGGRLLEVESRLDLIYSITRKYGGQVDDVLAYFEQISKEYALLTGK
                     NLSSDDLNKELKKLEKDLVSLASSLSQARHELAQQLEAEIQQELQDLYMEKANFRVQFI
                     KGKFSRDGNEHVEFYISTNPGEDYKPLVKVASGGELSRLMLAIKSAFSRKGGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGSNGQVLAISHLPQVIAIADYQFFIEKISDEHSTVSTV
                     RLLSNDERVEEIAKMLAGENVTQAALTQARELLKK"
     gene            complement(8796..9227)
                     /locus_tag="FGQ50_RS01705"
     CDS             complement(8796..9227)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="FGQ50_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="arginine repressor"
                     /protein_id="WP_003031395.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRHFVSDYEVGTQEAIVEYLKKSGITATQATVSRDI
                     KELGIVKIPLKNNTYIYELPKSASTSLKLADNNILKFELLGNMINLNLVPGSTAFVKRQ
                     IVEDFSKDIFSILADDDTILLIFRSEEMAHQVLEQIRNW"
     gene            complement(9220..10035)
                     /locus_tag="FGQ50_RS01710"
     CDS             complement(9220..10035)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932747.1"
                     /locus_tag="FGQ50_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_138283984.1"
                     /transl_table=11
                     /translation="MTKERVDVLAYKQGLFETREQAKRGVMAGLVVAVANGERFDKPGE
                     KIDETTELKLKGEKLKYVSRGGLKLEKALQVFEISVENQITLDIGASTGGFTDVMLQNG
                     ARKVYAVDVGTNQLAWKLRQDECVISMEQFNFRYAKATDFEETPSFASIDVSFISLGLI
                     LPALHKILAENGKVVALIKPQFEAGREQIGKNGIVKDKKVHQAVLEKVTDFMVEAGFSV
                     KDLDFSPIQGGHGNVEFLAYLEKNPHPEKLVKAMITTVVETAHKEFKDE"
     gene            complement(10001..10903)
                     /locus_tag="FGQ50_RS01715"
     CDS             complement(10001..10903)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031414.1"
                     /locus_tag="FGQ50_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_024052834.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-55, bitscore:
                     180.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQDEKLARIGQTIEGFYAQKVVSADLIEAILYSVNAGGKRIRPL
                     LLLELLEGLGLELTEAHFQVAAALEMIHTGSLIHDDLPAMDDDDYRRGRLTSHKKFGEA
                     MAILAGDSLFLDSYALIAETALPSQIKVNLIAELSLAAGTFGMVGGQVLDMQGEGKDIS
                     LAELQNIHANKTGKLLTYPFIAAGLIAEVAQPQQEKLRKIGQLLGLAFQVRDDILDITA
                     NFEDLGKTPQKDVAAEKATYPAIWGLDGAKRFFEKQIEETEHLLAELEVELAFSGAAIR
                     KIIESLKLNDERKSRCSSL"
     gene            complement(10900..11112)
                     /locus_tag="FGQ50_RS01720"
     CDS             complement(10900..11112)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="FGQ50_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_070584393.1"
                     /transl_table=11
                     /translation="MSKEKKFEENLADLEVIVQKLENGDVALGEAISEFQKGMQLSKEL
                     QKTLDQAEKTLVKVMQADGTETEME"
     gene            complement(11090..12430)
                     /gene="xseA"
                     /locus_tag="FGQ50_RS01725"
     CDS             complement(11090..12430)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="FGQ50_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_070584395.1"
                     /transl_table=11
                     /translation="MSEYLSVSTLTKYLKLKFDKDPYLERVYLTGQVSNFRRRPNHQYF
                     SLKDEKAVIQATIWGGVYKKLGFDLEEGMKVNVIGRVQLYEPSGSYSIIIEKAEPDGIG
                     VLAIQFEQLKKKLGEEGLFEECFKQALPQFPKKIGVVTSPSGAVIRDIITTVSRRFPGV
                     EIILYPTKVQGEGASTEVAENIRRANGRNDLDLLIIGRGGGSIEDLWAFNEEVVVRAIF
                     ESHIPIISSVGHETDTTLADFVADRRAATPTAAAELATPVTKLDLLAHLQQQQNRLATA
                     TSNRLTYNRERLAKLSQSVIFRQPERLYDSYLQKLDQLNLRLKQKIREYYNEEVQRARL
                     LQHRLEALAPLRQVQIYQERVAQLERLLRSNMAVVYDHKVAEVKRLSDALLMLDTSRIV
                     ARGYAIVKKDEQVLESIEKINKKDQLTILMRDGQIEVEVKDVERKEI"
     misc_feature    complement(12548..12566)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.57"
                     /tool="antismash"
     gene            complement(12620..12988)
                     /locus_tag="FGQ50_RS10815"
     CDS             complement(12620..12988)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FGQ50_RS10815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="conjugal transfer protein TraX"
                     /protein_id="WP_224783697.1"
                     /transl_table=11
                     /translation="MKEKKLYSFWKGLGLFLLPILLALPALFLSGYLASENISPLMVQI
                     IAFFIMAIPNIIVVEGGDVMVYLGLFFYIFRRHRIAQMVTLTPVSLFVYLTDPTSVQWM
                     MVFAVIPMYFYNGEKVVV"
     gene            complement(13007..13354)
                     /locus_tag="FGQ50_RS10820"
     CDS             complement(13007..13354)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017655.4"
                     /locus_tag="FGQ50_RS10820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TraX family protein"
                     /protein_id="WP_024052838.1"
                     /transl_table=11
                     /translation="MMLQSLKKISNATNLKILAILLVFLDHIYEMFGAFGAPMWITMLG
                     RVVFPLFMFLAADSFYYTHNRKAYLKRLLFMTWFMIIGNMIVSQFFTNGQVGLANNAFG
                     AFFLAGISICA"
     gene            complement(13656..14513)
                     /locus_tag="FGQ50_RS01735"
     CDS             complement(13656..14513)
                     /GO_function="GO:0052855 - ADP-dependent NAD(P)H-hydrate
                     dehydratase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023703.1"
                     /locus_tag="FGQ50_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="WP_024052839.1"
                     /transl_table=11
                     /translation="MEVVNCTLLEKVVQPRALHSHKGDYGRLLLIGGTYPFGGAIIMAA
                     LAAVHSGAGLVTVATDRENIAALHDHLPEAMAFDVQDKKLLTEQVQKADVVLIGSGLAE
                     SKLEKAVLRLVVKLVSEHQVFIMDGGAISLFSKEALPIPKAQTIFTPHQKEWERLSGLK
                     IAEQTVEKSQEAVNSFPAGTIVVQKKHGTTIFQSGNGNHFQLTIGGPYQATGGMGDTLA
                     GMIAGFARQFKTSSLLERVAAAVYLHSAIAEELNKEKYVVLPTEISKEIPKWMKKLAKK
                     ENML"
     gene            complement(14826..15680)
                     /locus_tag="FGQ50_RS01740"
     CDS             complement(14826..15680)
                     /GO_function="GO:0004488 - methylenetetrahydrofolate
                     dehydrogenase (NADP+) activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003023701.1"
                     /locus_tag="FGQ50_RS01740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_024052840.1"
                     /transl_table=11
                     /translation="MAKIIDGKALAEKLQAQLAEKVRKLKDQTGLVPGLVVILVGNNPA
                     SQIYVRNKERSALAAGLRSEVVRLPETTSQEELLALIDQYNQDSAWHGILVQLPLPKHI
                     DEEAVLLAIDPDKDVDGFHPMNMGRLWSGHPVMIPSTPAGIMEMFHEYGVELEGKRAVV
                     IGRSNIVGKPMAQLLLAKNATVTLTHSRTHHLSEITKEADILVVAIGRGHFVTKDFVKE
                     GAVVIDVGMNRDENGKLIGDVKFDEVSETASLITPVPRGVGPMTITMLMEQTYRACKRS
                     LKK"
     misc_feature    15636..15652
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.15"
                     /tool="antismash"
     misc_feature    complement(15800..15814)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.76"
                     /tool="antismash"
     gene            15948..17240
                     /locus_tag="FGQ50_RS01745"
     CDS             15948..17240
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003076587.1"
                     /locus_tag="FGQ50_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_070584400.1"
                     /transl_table=11
                     /translation="MQVVKRSLHYISRKKVKTLLVFLILTLISTALTSSFSIMGTTNNI
                     EKKIYDASNTGFTITSKTLERPLSLKTAEKLLENKEISKFNFKYDALASLTDKTVVKKK
                     QGVTRDNQNPVLNNLVAALGTSDSTLETTFASGVFKLEQGKPIRKDDKSKILIHEKLAK
                     KNHLKVGDKLKLKGASLKDEDAKQLHEVEFEIAGIFSGKKEEKQTGLSSDATENTVYMD
                     YESSQYLQGYKPADYKLSAAVYFVSNPNQIDKIINTVKKSKIDWKQTDLVKNSKAFEAV
                     SSSVTSFKQIINVLTFSIIIGSISVLSLILMFWLRERIYEIGVLLSLGISKAMIISQFI
                     LELVIISVFSTALASISCSYISTMVFKGFIKGGQQQDSSSAIFENIVPHLHTSTILMTY
                     GILLIIILLAVVGSSSIILHKKPKDILTDIS"
     misc_feature    complement(15982..15997)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.44"
                     /tool="antismash"
     gene            17252..17899
                     /locus_tag="FGQ50_RS01750"
     CDS             17252..17899
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003068204.1"
                     /locus_tag="FGQ50_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003030192.1"
                     /transl_table=11
                     /translation="MTILKMDSVSYQYNSLQENVLNQITASFEEGKFYAIIGKSGAGKS
                     TLLSLLAGLDTPTKGKILFEDQDIAQKGYNHHRRKQISLVFQNYNLIDYLTPMENVRLV
                     NSQANKDSLLQLGLNEKEIHRNVLRLSGGQQQRVAIARALASTAPIILADEPTGNLDEG
                     TAMDIIEVLIKSAKQKNKCVIVVTHSKELANKADVVLELSNKNLVEVTKNYK"
     gene            17923..19311
                     /locus_tag="FGQ50_RS01755"
     CDS             17923..19311
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041535.1"
                     /locus_tag="FGQ50_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_070584402.1"
                     /transl_table=11
                     /translation="MLTIKNALAYVWRKKIKTLIIFLILLAISTLTLGSIAVKNATDAA
                     SKETFKNITSSFSMQINREVNQGTPRGAGNLKGEDIEAVEKVKGISGYIKRMNVIADLI
                     DHQLVESGETDFESEDRKQKFGRAIMATGINDSSKDDKFTAETFKLVEGRHINKNDKNV
                     ALIHKDFAEKNKLKVGDTINIKSNTYDYDNVRKANKTTKVTVIGIFDGKNKGGVSSPQE
                     LYENTFITDLETTKTLQGSTDKNAIYQDATFFVNGSQDIDKVMAKVKEISSIDWEAYTL
                     VKSTSNFPALQSSINGIYGVTGNLLIGTLIFGAIVLTLVLFLWINGRRKEMGIMLSMGI
                     SKTKIFFQFITEVLFVSIFSFIGAYFAGSAVSKVMGNSILKQVTSGIAEKLAREGKSAN
                     LGGGAEVDDFNKTLTSLNVHVSPDDMTKVVIFGLAIIIVSVLIASITLLSKQPKDLLMG
                     DNSK"
     gene            complement(19631..20173)
                     /locus_tag="FGQ50_RS01760"
     CDS             complement(19631..20173)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003068200.1"
                     /locus_tag="FGQ50_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="WP_024052843.1"
                     /transl_table=11
                     /translation="MVRPTSKTELISAATQQYAKLQSLISQLTEEELKTPFDFSKDEKK
                     KEAHWKRDKNLRDVLIHLYEWQQLLLDWVHSNQNGVEKSFLPAAYNWRSYGEMNVAFWQ
                     KHQQTPLEKAIKLLHQSQEKVLTMAETFTNEELFSKGIYKWVGGSTLGSYFVSCTSSHY
                     DWAMKKLKAHQKNCKNQ"
     gene            complement(20247..20381)
                     /locus_tag="FGQ50_RS01765"
     CDS             complement(20247..20381)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031275.1"
                     /locus_tag="FGQ50_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="WP_003023693.1"
                     /transl_table=11
                     /translation="MSTIIVFIIILVLAGAAMHHIIKGKGRCGDCDCQCEIKEKMRQK"
ORIGIN
        1 aatggaaaag aacgtctata ctcatggaga aagacacccc cagaatacga aaagaagccc
       61 aaaagatact tgatactaag ataactaacc ttttgaataa cctaaaaacg tcagaaatgc
      121 tctttacagc tcttttagac cagtggtggg gattttatca gcaagagata aaacggtcgt
      181 ctatcgcttc gttaatgggc aatatcaaag aaataagaga gtcttttgga ctgaatgtaa
      241 aagtggtcaa tattgatccc aaatatgtcc aaacttacct agacaatctc gactgctcca
      301 gaaacaagaa agaacgtcac aaatctatgc tcaaccttgc ttttgattac gctgttgatc
      361 tgaatattat taaagataat ccgtctcggc gggccaagct cccgcgaata aagaaaactt
      421 tggaagattg gaagaaaatt gaagaaaaat atcttgaaga ggatgaaatc caaccgcttc
      481 ttaaagagtt atatcgacgc cccaacactt accgtttagg gttactgtct gagttcatga
      541 gcctaaatgg ctgccgtatt ggtgaggcag tcagtatcga accaacaaat tataattttg
      601 aaaccagaat cctacagttg cacggaacct atgaccacac agagggctac cgtaacggcg
      661 aaaaaacaac tcccaaaact cttgcctcct accgggaaac aatcatgacc aaccgtgaaa
      721 tggaaatcct caaagaattg gagttcatga atgaactgga aaaaaacacc aatctacgat
      781 atagagacat gggctacctt ttcacaacta aaaacggagt tcctattcaa actaactctt
      841 tcaacctagc tcttaaagct gccaacgagc gattggaaac gccgattcgg aaaaatctta
      901 ccagccacat cttccgtcat actctagtca gccgtctggc tgaaaacaat gtcccactta
      961 aagctattat ggatcgtgtc ggtcatgctg attcaaagac gactgttcaa atttacaccc
     1021 acatcaccaa gaaaatgaag tcaaatgtgg ctgacatcat ggaaaactat tgattttatg
     1081 ccccaaaaat gccccaaaac acaagaaaaa gcctattgta caagctagaa agcttgacgc
     1141 aataggcttt ttaaatcgct attatttaac agcgtcttta agagctttac ctgctttaaa
     1201 tgctggtact ttagaagctg ctattgtgat ttctgcacca gtttgtgggt tgcggccttt
     1261 acgagctgca cgttcacgaa cttcaaagtt accaaaacca atcaattgaa ctttttcacc
     1321 agctgcaagg tattcagtta ctgctgcaaa taccgcatca actgctgctg ctgaatcttt
     1381 cttagtcaat tctgtagctt ctgctacttt tgcaatcaaa tcttgtttgt tagccattta
     1441 acaaatcctc caaaatattt tatgaattag tagtcactaa ctctaacaag tattatcata
     1501 tctaaaaaat gttattaggt caagcacaaa acgaactttt ttcaattttt ccaaagatat
     1561 caaacttatt catagcgaac gaggactgcc cacgcatttt cacctgtatg tgtttgaata
     1621 atagaaccag tcttcaaaac agaaatcgtt ttttccacac acggttgcaa aatctgtttc
     1681 atttcgttcg ccaattcggc agttcctgca tacgaaattc caatctctgc cactttttta
     1741 tcttttaagc tttcaactaa atcattaacc cattttttga aggtttttac accacgcccc
     1801 ttaacaatcg gttgtaattc attgtttttc atttgcataa ctactcgaat attaagcaac
     1861 gaactgagaa gcccagtcac acgactaata cgaccacctt ttacaagatt ttcaagcgtt
     1921 gacacaccga tatacaattc tgttttttca cgtacttctt cgattcttgc taaaatagca
     1981 tcaaagtctg caccttcttt tgctagtttt gcagcttcaa ccacttgaaa cttcaaagct
     2041 tgatccgtaa aagagctatc aatcactgtt acatctacat ttgccaaggt tgccccttgt
     2101 cgtgcagctt cgaccgttcc agacaaagca tgcgacatat ggatagaaat gattttatcg
     2161 gcagtttctc cgagtgtttc aaagatttct gcaaaaacac caactggtgg ttgactggtt
     2221 ttcggtagat ttttgcttga ctgcatcaaa cgaagaaact ctccttcttt taagtcagcg
     2281 tctgaataaa caacaccatc taccattaca gacaaaggaa cgattgtaat ctctaaatcc
     2341 tctacaactt gcggttcaat cgtaatagat gaatccgtta caattttgat ttttgtcata
     2401 gttttcctac ttttataaat tttatctatt taatttatta tatcaaaaaa ataacttttt
     2461 gtggaataat ttttctggat aaaatgtgta aaaggtgtgt agagctttct atttttctaa
     2521 ataaacagaa ttattaaatt ttcagaaaat aattgacact gttttatttt tttgttagcc
     2581 tagtgatgta tcttattgaa gctgttgctt tgaagaaagg gttgataaat gaaacagaca
     2641 aaatttttag gaattctttg tcttgctctt gttatgattt caattacagt tggttctggt
     2701 cacttttcgt ggtggcagct gctacacgga gataagcaga ctgggctgct atttttagag
     2761 tcgcgcttgc caaggacagt cagcattctc ctagcaggct ctagcatgag cattgccggg
     2821 cttcttatgc agactgttac acaaaatcat tttgctgctc ctagcacggt tggaacggtc
     2881 gaggctgcaa aatttggtat gttgcttagt ttatttttct ttccgtcagc cacattagcg
     2941 caaaaaatgc tatttgcttt tgtatctgct atttttttta cgattatttt tattagactt
     3001 atcagaaaat tctcatttaa agaaaaatgg ttgttaccgc ttgtcggaat tatttatagt
     3061 ggagtgatta gtgcagcagg agaaatcatt gcctatcgtt ttgagcttgt ccaaagcatg
     3121 acttcatgga cacaaggctc tttttccatg attcagaaac atcaatatga atggttattt
     3181 ttaagtttaa tcatcttgat tgcagtatgg aagctatcag ccacgtttac cattatgaat
     3241 ctaggggaag acgctagtca taatctaggc atttcctttt accaaatgga aggaatgacg
     3301 ttgtttctca ttgcattgac gacaagtgtg acgatgatta cagtcggctc tcttccattt
     3361 atcggagtca ttgttccaaa catcattcgg aaattttatg gtgaccatat cacacgcatt
     3421 aagggactga ccgcattaac tggttcctgt ctcatcttga tctgtgatat tgtagctcgt
     3481 ctagtcattc gcccttacga agtctccgtc agcttgattt taggaatttt gggtagtttg
     3541 gcgttcgtgt atcttttgtg gcgaggtgct gctcatgaat aaaatgaaga gtcaaacaag
     3601 aaatcgctta cttctattgc ttttgttagc tagcttgagt ggcttgttat atctcatgcc
     3661 aatggaatat cctttaacag gttttattat gaaattgcgc tcgcaaaagt tactagccta
     3721 tcttttagtc gccatagctg gaggtcttgc tacaatcagc tttcaaacaa tcacagagaa
     3781 tcgtttttta acaccaagca ttcttggaat ggaatctctc tatgtcttta tgcagacgat
     3841 ttatcttttc tttgctagca aattcatctg caatactggt catcctttgc ttgagtttat
     3901 cttagtctta ctcatacagt gtggcttctt tttctgcctg caacctgcat taaaaaagct
     3961 actccagcaa ggatttgtat ttattttatt gatttgcatg gcactaggga cgctctttag
     4021 aagcgccagc acattcttgc aggtgctaat ggatcctaat gaatatgata aactgcaaac
     4081 aaaactattt ccttcctttc aacgaataaa tatggatatt ctatctgtcg ctgcaatcat
     4141 cattggacta gcaggtttat atttgttaaa gaagaacgct attttgaatg tttttcattt
     4201 ggataaaaag acagcgacta ttttaggtgt agaagttgaa aaagagcaaa aaaagatact
     4261 atgggcaatt gttttgctga cttcaacgac aactgctctc gttggaccta tgatgttctt
     4321 cggctttatg atgtctaatt tagcctatct gttaatcaaa gaataccaac acaaatggtt
     4381 gttctcagta gcaattttac tcggttttct ctctctaact actggacaaa tgctggtaga
     4441 gcgcgtcttt cagctccaaa tcaatgtcag catggtcatt gagcttgtcg gagggttatt
     4501 cttcttttat cttttagcta aggaggtaaa acgctagaat gcaattaaaa aacgttggca
     4561 aatcatttgg aaatcaagca attttagaag atattcaact gaatatttca ccgagcaaat
     4621 tcaccgcttt tattggtcca aacggtgccg gaaaatcaac gctgctttcc attatgagtc
     4681 gtttgctcaa gaaagatcaa ggttttctca gtatcaaggg aaaagaaatt gaagcttgga
     4741 attcaaaaga gttggccaaa gaattaacga ttttaaaaca aaaaatcaat taccaatcta
     4801 aattaacggt tgaagaattg gtttccttcg gtcgctttcc ttatagtcag gatcgtttga
     4861 caaaagaaga tttcaaaaaa gtggagcaag cattggaata tttggatatt gctgatctgc
     4921 gagaacgttt cattgatacg ctttcaggcg gtcaattgca gcgcgttttt atcgctatgg
     4981 tgctcactca agacactgat tttatctttt tggacgagcc actaaacaat ctagatatta
     5041 agcaaagtat ttctatgatg aaaatcttgc ggtctctcgt tgatgactta ggaaaaacga
     5101 ttatcattgt cattcatgac atcaatattg ccagtcagta tgttgatgaa attgtcgcct
     5161 ttaaagacgg aaaagtcttt tatcaaggta caaccaatca ggtcatgaga aaagaaattt
     5221 tagatccatt gtatgaaatg gacattaccc ttggggaaat caatggtaaa aaagtttgta
     5281 tttacctata aatattaatt ttggaggaat tttaatgaaa aagaatacaa aaacactact
     5341 tctatctctc ttcgcagctg ttgcagttgt gctactcgct gcttgcagcg acaataaaca
     5401 gtccaattca aaaacgacaa actcttcatc tacttctagt gaagtcacta tcaaaacagc
     5461 aaatggagat gtgaaagtcc ctaccaaccc taaaaaaatt gtaacactgg atttaggtgc
     5521 agctgatacc attcgtgctt taggaaaaga aagcagcatt gtcggtatgc caaagaaaac
     5581 tctgcctgct tacttaaaaa atttaccaag tagcattaaa aatgtaggta gcatgaaaga
     5641 accgaatatg gaagctatcg cagctttaaa actagacttg attattgctt ctggtcgtac
     5701 agctcaatat gtcaagaaac tcaaggaaat tgcccctact gtattattcc aaacagacaa
     5761 caaagactac tggggttcta ccaagaaaaa catcctttct ttagcaagta tctttggaga
     5821 agacggaacc aaaaaagcta aaagtgaatt agctacatta gacaaggaaa ttcaaaccgt
     5881 tgttgctgcc aatgaaaagt caaataaaaa tgctcttgcg atgatgttaa atgaaggtgc
     5941 aatatctgct ttcggagcta aatcacgttt tgctttcctt tacagtactt tgaaattcaa
     6001 accaacagat gctaaaatca aagaatcaag acatggacaa gaagtcagct ttgaaagtat
     6061 caaacaaatc aatccagata ttatctttgt tctgaaccgc actcttgcta tcggtgggga
     6121 caattcggcc aataaagact tactgaataa ctcactgatc caagaaacaa atgctgctaa
     6181 aaacaaaact attgtaaact tgacatccga cctctggtac ctaagcggag gcggactcga
     6241 atccacaaaa ttgatgattg aagatgtaaa aaatgtagct gggaaataat ataaaagagc
     6301 tggagaaaac cttaaatgaa ttttctccag ctcttttatc atcctcaact tctaattatc
     6361 ctctaccgcg aaaccatcat ttgtgatgaa atgatgttct aaaattccct catttccaaa
     6421 taaaactccg tggagaacac cgccatagac agctccgcca tccatgccaa ttttttgatc
     6481 ctgcgtttgc caaaggcgac ttgtcccagg catctcagaa aaaagataaa aagtcggagt
     6541 atgtccaaat acaattattt tccctgtttg attgagacct tgatgaaagg gctcacgtat
     6601 ccaaaccttt tgataatcgc ttgtttcatg ccaatctttt aaagttaagt caactccagc
     6661 gtgtacaaaa atatagttat ctgtttcaac aaagaaaggc atctgacgaa taaaatacac
     6721 gaggtctggc gcctcttccg acacgcgctt tgcgtcttca actccatcaa caggagtatc
     6781 tagaggtcgc cccaaaatag aattgattgt tgtgtcaccg ccattgcgac gataatgagc
     6841 atagccgctc tcaggattgt ccagccaagt taaaaacatg tattcgtgat tcccagaaat
     6901 acaaatcgct ccttgcttgt cgacaagact tttcacacac tctaaaaccg ctcggctgtc
     6961 ctcgccgcgg tcaatcaaat ctcccaaaaa gatgagctga ctttctccat cccatttttt
     7021 gagtaattct tttagcattt ttgcttttcc atgtacatca ccaattacaa aataatttgt
     7081 catgattacc tcctgataac aacccattta gcacaagcca aagagtattt cattttttca
     7141 agagctctct agcctgcgtg agggctgctt gggtcacatt ttcgcccgcc aacattttgg
     7201 caatttcttc gacacgctca tcatttgata acaagcgaac agttgaaacg gtcgaatgct
     7261 catcagatat tttctcaatg aaaaattgat aatctgcaat ggcaatcact tgtggtaggt
     7321 gcgaaattgc gaggacttgt ccgttcgagc caattttatg aatcttttga gcaatagctt
     7381 gtgcaacacg tcccgataca cctgtatcta cttcatcaaa gacaatgctg gttttgcctc
     7441 ccttgcgaga aaaagcagac ttgattgcca acattaaacg agacaattca ccacctgaag
     7501 caaccttaac gagcggtttg taatcttcac cgggattagt cgaaatataa aattcaacgt
     7561 gttcattccc atcgcggcta aattttccct tgataaattg aactcgaaaa ttcgcctttt
     7621 ccatatagag gtcttgcagt tcttgctgaa tctctgcttc taactgctgg gctaattcgt
     7681 gccgagcctg actaagactg cttgctagag aaaccaagtc tttttccagc tttttcagct
     7741 ctttgttcaa atcatctgat gaaagatttt tcccagtaag tagagcatat tctttagaaa
     7801 tctgctcaaa ataagctaag acatcatcta cttgaccgcc gtatttgcga gtaatactat
     7861 agattaaatc taggcgactt tctacttcta agagacggcc accatcaaaa tccaagtctt
     7921 ctagaatatc ctccaaacgc tttgtcacat cttccaacac atagtaagat tcagaaaggt
     7981 tggtcgcaat ttctttgtaa gtggcgtcat agtcttcaat agcttccatg tcattcatgg
     8041 cagaacgaat attcgctaaa ctagaaaatt cttcatcatc cagcatggca taggcatttg
     8101 tcaaagtgtc cgcaatctgc ttatgattga gtaacttatc acgctcttgg tttaaagcta
     8161 aatcttcgct agcttttaaa ttagctgctt caatctctgc aatttgatat tccagcatgt
     8221 caatccgcgc tttattttct tcttgattct tttgaattgt taagatctgc ttacgcaact
     8281 gacgatactg gtcaaaagtc tgttgataat cagctttgag cttgaaaaat gcgtcagctc
     8341 caaactcgtc caacatggca atatgcagct gcggtcgcat gagttcttct tgatcgtgtt
     8401 gaccgtgaat atccaccaaa tgctgtccaa cagctcgcaa gacagacaaa ttaaccattt
     8461 gaccattaat acgactgaca ctacgcccat tttgaaaaat ttcccgccga ataatcagct
     8521 cctctgtcat atcaagccct tgctgctcaa aaatttcaac caaagcctta ctctgctcaa
     8581 ttgcaaaaag cccttcaatc tctgcttttg atgcaccgtg acgaatcaca tctgttgtcg
     8641 cgcggcttcc tagcatcatg ttcatagcat caataataat agactttcca gcccctgttt
     8701 cacctgtcaa aacagtcatg ccttgctcaa aattgaggga aatctcttca ataattgcaa
     8761 aatttttaat ggaaatttca agtaacatag gctatctacc aatttctgat ttgttccaat
     8821 acctgatgag ccatttcttc actacggaaa ataaggagaa tcgtgtcatc atcggctaaa
     8881 atactaaaaa tgtccttaga aaaatcttct acaatttgtc gcttcacaaa agctgtgctt
     8941 ccagggacaa gattgagatt gatcatattt cccaatagct caaactttaa gatattattg
     9001 tctgctaact tcaaactcgt actagctgat ttcggtagtt cataaatata agtgttattt
     9061 ttcagcggaa ttttgacaat gcccaattct ttaatatcac gcgaaacagt tgcctgtgtt
     9121 gctgtaattc ctgatttctt cagatattct acaattgctt cttgtgtccc aacttcatag
     9181 tccgacacaa aatgtctaat tttttctaat ctttcctttt tattcatctt taaattcctt
     9241 atgtgctgtc tctacgaccg ttgtaatcat tgcttttact agtttttcag gatgaggatt
     9301 tttttccaaa taggctaaaa attccacatt cccatgccca ccttgaatag gggagaaatc
     9361 taaatctttg acggaaaatc ctgcttcaac cataaagtcc gttacttttt ctaaaactgc
     9421 ttgatgcact tttttatctt tcacaatccc atttttgcca atctgctctc ttcctgcttc
     9481 aaactgaggt ttgataagtg caacgacttt tccattttca gccaaaatct tatgcagagc
     9541 tggcaaaatg agaccaagcg agataaaact gacatcaatg gaggcaaagc taggtgtctc
     9601 ctcaaaatca gttgccttgg cataacgaaa attaaactgc tccatgctga tgacgcattc
     9661 atcttgtcgg agtttccatg ccagttgatt ggtgccgaca tctactgcgt agactttcct
     9721 tgcaccattt tgcagcatga cgtccgtaaa cccacccgtt gatgccccaa tgtccaacgt
     9781 aatctgattt tcaactgaaa tctcaaaaac ctgcaaagcc ttttctaatt ttaagccacc
     9841 acggctaaca tatttgagct tttcgccttt gagttttaac tcagtggtct catcaatttt
     9901 ctcgccaggt ttatcgaaac gctcaccatt cgcaacagca acgactaagc ccgccatcac
     9961 accgcgcttg gcctgttctc ttgtttcaaa aagcccttgc ttataagcta gaacatctac
    10021 tctttctttc gtcattgagt tttaaacttt ctattatctt tctgatagcc gcgcctgaaa
    10081 aagcaagctc tacttctaat tctgccaata aatgctctgt ttcctctatc tgtttttcaa
    10141 agaatcgctt tgctccatcc aaaccccaaa tggctggata ggtggctttc tctgctgcca
    10201 catctttctg cggtgtcttc cccaagtctt caaagttcgc tgtgatatct aaaatatcat
    10261 ctcgcacctg aaaagctaaa ccaagtaatt gaccaatttt tcttaatttt tcctgctgtg
    10321 gctgtgccac ttccgcaatc aaacccgcag caataaaagg ataggtcagg agtttaccag
    10381 tcttattggc atgaatattc tgcagctctg ctaaactgat gtcctttcct tcgccctgca
    10441 tatcaaggac ttgacctccg accataccaa aagttccagc cgctaatgac aattctgcaa
    10501 tcaaatttac cttgatttga ctaggtagtg ccgtttctgc tatcaaggca taagaatcca
    10561 aaaagagaga atctcctgct aaaatagcca ttgcttcgcc aaatttcttg tggctggtca
    10621 agcgaccacg acgataatca tcatcgtcca tagccggcaa atcatcatga atcaagctgc
    10681 ctgtatgaat catttcaagc gctgctgcca cttggaaatg tgcttctgtc agttccagtc
    10741 ctaaaccttc taataattct aaaagtaaaa gaggacgaat tcgcttaccg cctgcattaa
    10801 cagaatagag gattgcttct atcaaatcag cggacaccac tttttgagca taaaatccct
    10861 cgatagtctg tccaattcta gctaattttt cgtcttgttt cattccattt ccgtttctgt
    10921 gccatcagcc tgcataactt ttaccagcgt tttttctgcc tgatctagtg ttttttgcaa
    10981 ttcttttgag agctgcatcc ccttttgaaa ctcagaaatc gcttctccca aagccacatc
    11041 tccgttttct aacttctgta cgataacttc taagtctgct aaattttctt caaatttctt
    11101 ttctttcgac atcttttacc tcaacttcta tctgaccatc tcgcatcaaa atggttaatt
    11161 gatctttttt attgattttc tcaatagatt ctaacacctg ttcatctttt ttgacaatag
    11221 cataaccccg agccacaatt cggctagtat ccagcatgag caaagcgtca gacagacgct
    11281 tgacttcagc cactttatgg tcataaacaa ctgccatatt actgcgcaga agccgttcca
    11341 actgagctac acgctcttga taaatctgaa cctgccttaa aggagctaga gcctccaaac
    11401 gatgttgtaa aagccttgcc cgctgcactt cctcgttata atattcgcga attttttgct
    11461 tgagccgtaa atttagttga tctaattttt gcaggtagct atcatacagt cgttctggtt
    11521 gtcgaaaaat gacagactga ctcagcttag ctaatcgctc acgattgtaa gtaagacgat
    11581 tcgatgtggc agttgctaac cgattttgtt gctgctgcaa gtgtgctagg agatccagct
    11641 ttgttacagg tgttgctaat tcagcagccg cagtcggcgt tgcagcccgt ctatctgcaa
    11701 caaaatctgc caaggtcgta tctgtttcat gccccacact cgaaatgatc ggaatgtgcg
    11761 attcaaaaat tgcacggaca accacttcct cattaaacgc ccagagatct tcaattgagc
    11821 caccacctcg accgataatg agtaaatcta aatcatttcg cccattagca cgacgaatat
    11881 tttctgctac ttcagtagaa gctccttcgc cttgcacctt cgtcggataa agaattatct
    11941 caactcccgg aaaacgacga ctaacagttg tgataatatc gcgaatcact gctccactag
    12001 gactggtcac tactccaatt ttctttggaa attgcggtaa agcttgctta aagcactcct
    12061 caaaaagccc ttcctcgcct agctttttct tgagctgctc aaactgaatt gccaaaactc
    12121 cgataccgtc tggctccgct ttttcaatga taatagaata agatccactt ggttcatata
    12181 gttgaacacg accgatgaca ttaaccttca taccctcttc caagtcaaaa cctaacttct
    12241 tataaacacc accccaaatt gttgcctgaa tgactgcttt ttcatctttg agagagaaat
    12301 attggtgatt aggtcgccta cgaaaattag aaacttgccc cgtcagataa actcgttcta
    12361 aataaggatc tttatcaaac tttaatttta agtatttggt caaggttgac acggataaat
    12421 actcagacat tcctctcctt tcatttcctg taatgcttct ttattcataa tttttattat
    12481 accaaacaat ctataaaaaa tcatttccag ccctcaacga aaaaggaaag actagtttcc
    12541 catatcttaa gcagagccta gcccaacaaa cttgccaaaa tatacaaaag atagatatgc
    12601 acaggataga aaaataactt cataccacga ctttttcacc gttgtaaaaa tacattggaa
    12661 tcaccgcaaa aaccatcatc cattgcacag acgttggatc tgttagatac acaaataaag
    12721 atactggtgt taatgtcacc atttgtgcta tgcggtgtct gcggaagata taaaagaaaa
    12781 gaccaaggta aaccatgaca tcccctcctt caaccacgat aatgtttgga atggccatga
    12841 taaaaaaagc aataatttga accatcagag gtgatatatt ttcactggct agataacccg
    12901 atagaaacaa agccggcaga gccagaagaa tcggtaaaag aaaaaggccc aatcctttcc
    12961 agaatgaata aagtttcttt tctttcatac cctcaaccat caaatcctaa gcacagatag
    13021 atatgcccgc taagaaaaag gcgccaaaag cattattcgc cagcccaact tgaccattag
    13081 tgaaaaattg actgacaatc atgtttccaa taatcataaa ccatgtcata aagagcaacc
    13141 gtttcaaata agcttttcga ttatgcgtat aataaaaact atcagctgcc agaaacataa
    13201 aaagaggaaa aactacgcgt cctagcattg ttatccacat cggggcgcca aaagcgccaa
    13261 acatttcgta gatatgatct aaaaacacaa gtaaaatagc taaaattttc aagttcgttg
    13321 cattcgatat tttctttaaa gattgtaaca tcatacattc tccatttctt tttttcaact
    13381 agcataatct tactgaaatt ttcccactct ttccattaca taaacttaca ttttcagaaa
    13441 gaaaagtgac atttttgtag ggcagaaaaa ataaggtcaa gataaaacat ctcaacctca
    13501 ttaaatacaa tgaattttca taagatagtg gatattgaaa aagtttattc tccctttcaa
    13561 cttgtactaa acctcatgag ctaaatatta cttttataaa tagctaataa aagttaaact
    13621 ttccaatttt ttaaatgctt tttcaggttt tttcattata acatattttc ttttttagct
    13681 agcttcttca tccacttagg gatttctttg ctgatttccg ttggcaagac tacatatttt
    13741 tctttgttta actcctctgc aatggctgaa tgcagataga ctgctgctgc tacacgttcc
    13801 agtaaagaac tagtcttgaa ctgccttgca aaacccgcaa tcatgcctgc cagagtatct
    13861 cccatgccac ccgttgcttg ataaggacca ccaatagtca gttgaaaatg gtttccattt
    13921 ccactttgaa aaatagtcgt tccgtgcttc ttttgaacaa cgatagttcc agcagggaag
    13981 gaattaacag cttcttggct tttttcaacc gtttgctcag ctatctttag tccgctcaac
    14041 cgctcccact ctttttgatg tggggtaaaa atcgtctgtg cttttggaat tggcagagct
    14101 tctttgctaa agagggaaat agctccaccg tccatgatga agacttgatg ttcactaaca
    14161 agtttcacta ccagccgcaa aacggctttt tcaagtttac tttcagctaa acctgatcca
    14221 atcaatacta catctgcttt ttggacttgc tcggtcaata gctttttatc ttgtacatca
    14281 aaagccattg cttctggtaa atgatcgtgg agagctgcga tattttccct atccgtcgcc
    14341 accgtcacta gaccagctcc gctatgaact gcagctaagg ctgccatgat aatcgctcca
    14401 ccaaaaggat atgtcccgcc aattaacaac aagcgaccgt aatccccctt gtgactatgg
    14461 agtgcacgtg gctgaacgac cttttccaat aatgtacaat tgaccacttc cattattttc
    14521 tccttttgca tactgcgatt ccccttgtct acctctattt tatataaagg aaaaaagacc
    14581 tgtctaggac attcttgtct cagactcgtt tactttctag aataaaactc aatacgcaat
    14641 tgagtggcct ttattacgct gatgatatca gcttttacaa acctactcaa ccttgcaggg
    14701 tggggcaaca aatttgattt cttacgaaat accattttta tacgtaattt tcacgattac
    14761 actctttctg tgggggagtt tgtagtataa tcatggctgt tgtctgtccc actcccatga
    14821 cattcttatt ttttcaaact ccgtttacac gctcgatagg tttgctccat gagcatggta
    14881 atggtcatcg gaccaacccc tcttggtaca ggagtaatga gacttgcggt ttcagatact
    14941 tcatcaaatt tcacatcgcc aatcaattta ccattttcat cacgattcat acctacatca
    15001 atcacgaccg cgccttcttt gacaaaatct ttagtcacaa aatgtccgcg accaatagct
    15061 acaactaaaa tatcagcttc ttttgtaatc tctgacaagt gatgtgtccg tgaatgcgtc
    15121 agagttactg ttgcattttt agcaagtaaa agctgtgcca tgggctttcc gacaatgtta
    15181 ctccgtccaa tgacaacagc acgtttacct tctaattcta caccgtactc atgaaacatt
    15241 tccataattc cagcaggtgt ggagggaatc atgacaggat gaccactcca aaggcgtccc
    15301 atattcattg ggtgaaagcc gtccacatct ttatcagggt caattgctaa caacactgcc
    15361 tcttcatcaa tatgctttgg cagtggcaac tgaactaaaa tcccgtgcca agctgaatct
    15421 tgattgtatt ggtctatcaa agcaagcaat tcttcttgac tagttgtttc tggcagacgc
    15481 accacttcgc ttcgaagtcc tgcagccaaa gctgaccgtt ctttatttct cacatagatt
    15541 tgactagctg ggttattgcc gaccaagatg actacaagtc caggaactaa gcctgtttgg
    15601 tcttttaatt tacgaacttt ctctgctaat tgtgcttgta atttttctgc caaagctttt
    15661 ccgtcgatta tctttgccat ataactctca tttctatttt cttcattcta ttatagcaga
    15721 aattcattca tttgtcctat agactttttt atagaaagtt atagagcgaa accaaccttg
    15781 tctttccacc tttttctact attttatgaa aatttacaca aaaaacagaa aaaaaggagc
    15841 caaaaaactt aaaattatct taaaccttaa aactatttta aggtaactgc tttaacatag
    15901 aacacggtac caatttagtt taaaaattta aagaagggaa gaagacaatg caagtagtga
    15961 aacgatcttt gcattacatc agtcgaaaaa aagttaaaac tcttcttgta tttctgatac
    16021 ttactctcat ttcaactgcc ttaactagta gcttttctat tatgggaacg actaataata
    16081 tcgaaaagaa aatctatgac gcatcaaata ctggctttac aataactagc aaaacacttg
    16141 aacgaccact ttcactaaaa acagcagaaa aattacttga gaataaagaa atttcaaaat
    16201 tcaacttcaa atacgatgct ttagcaagtt tgacagataa aactgttgtc aagaaaaaac
    16261 aaggtgtcac aagagacaat caaaaccctg tcctcaacaa cctagtcgca gcattaggaa
    16321 caagtgattc tactctagaa acaacctttg caagtggtgt tttcaagctt gaacaaggaa
    16381 agccaattcg taaagacgat aaatctaaga ttctcatcca tgaaaaatta gctaaaaaga
    16441 accatttaaa agttggagat aaactaaaac taaagggagc ctccttaaag gatgaggatg
    16501 ctaaacaact ccatgaagta gagtttgaaa ttgctggtat cttctccgga aaaaaagaag
    16561 agaaacaaac cggtttaagc tcagatgcga cagaaaatac tgtctatatg gactatgaat
    16621 cgagccaata cttacaaggc tacaaaccag ctgattataa attatctgca gccgtttatt
    16681 tcgtatcaaa tccaaatcaa attgataaaa tcatcaatac agtcaaaaag tcaaaaattg
    16741 attggaagca aactgatctt gttaaaaact ctaaagcttt tgaagcagtt tcttcttctg
    16801 ttaccagttt caaacagatt attaatgttt taactttcag tatcattatt ggaagtatca
    16861 gcgttctttc cttgattctc atgttctggt tgagagaaag gatttatgaa atcggagtac
    16921 tattatctct cggtatttca aaagcgatga ttatctctca attcatactg gaactggtta
    16981 tcatatcagt atttagtacg gcactagctt ctattagttg ctcttatatt tccactatgg
    17041 tattcaaagg gtttataaaa ggcggtcaac aacaagatag ctcatccgct atttttgaaa
    17101 atatcgttcc gcacttacat acctctacta ttctgatgac ttatggaata ctgctcatca
    17161 ttattttact tgcagtagta ggttcatctt ctattatcct acataaaaaa ccaaaagata
    17221 ttttaaccga tataagttaa ggagacaaaa catgacaatt ttaaaaatgg attcagttag
    17281 ttaccaatac aatagcctac aagaaaatgt attgaatcag atcacagctt catttgaaga
    17341 aggaaaattt tatgctatta tagggaaatc tggtgcagga aaatcaacct tgctttccct
    17401 tcttgcagga cttgatactc ctacaaaagg aaaaatcctc tttgaagatc aagacatcgc
    17461 tcaaaaaggc tataaccatc acagacggaa acaaatctcc ctggttttcc aaaattataa
    17521 tttaatcgat tacttaactc cgatggagaa tgttcgactc gtgaattctc aagcaaataa
    17581 agatagcttg ttacaacttg gactcaacga aaaagaaatc catcgtaacg tattacgatt
    17641 atcaggtggc cagcagcaac gggttgctat tgcacgcgct cttgcatcta cagcaccaat
    17701 tatcttagca gatgaaccaa ctgggaactt agatgaaggt actgccatgg acatcattga
    17761 agtcctaatt aaatcagcta aacaaaaaaa taaatgtgtg attgtggtga cacacagcaa
    17821 agagttagct aataaagcgg acgtcgtctt agagttaagc aataagaact tagtcgaagt
    17881 cactaagaat tataaataag agctccaagg agaagaaatt atatgttaac gataaagaac
    17941 gcccttgcct atgtatggcg caaaaaaata aaaacactga ttatcttttt aatcctgtta
    18001 gccatctcta ctttaacact tggcagtatt gctgttaaaa atgcaacaga cgctgcttca
    18061 aaagagactt tcaaaaatat cactagcagt ttctcaatgc agattaaccg cgaagtgaac
    18121 caaggtaccc ctcgcggagc aggaaatctt aaaggcgaag atatcgaagc tgtggaaaaa
    18181 gttaaaggta tctctggcta catcaaacga atgaatgtta tcgctgactt aattgatcac
    18241 caattggttg aatctggaga aaccgacttt gaaagcgaag atagaaaaca aaaattcggc
    18301 cgtgccatta tggcaacagg tatcaacgat tcatctaaag atgataaatt taccgcagaa
    18361 accttcaaac tagttgaagg tagacatatc aacaaaaatg acaaaaatgt tgctttaatt
    18421 cataaagatt ttgcagaaaa gaacaaactt aaagtcggcg atacgattaa tataaaatcg
    18481 aatacttatg actatgataa cgttcgcaaa gctaataaaa cgactaaagt gacagttatc
    18541 ggaatttttg acgggaaaaa taaaggaggc gtttctagtc ctcaagaatt gtatgaaaat
    18601 acctttatca cagacttaga aacgactaaa actttacaag gttcaacaga taaaaacgct
    18661 atttatcaag atgctacttt ctttgtaaat ggtagccaag atattgataa agtgatggcg
    18721 aaagtaaaag aaatatcatc tattgattgg gaagcctaca cccttgttaa gagcacaagc
    18781 aacttcccag cacttcaatc ttctattaac ggtatttacg gcgttactgg aaacctctta
    18841 atcggaactc taatctttgg agcgattgtt cttacgctag tcttgttctt atggatcaat
    18901 ggtcgtagaa aagaaatggg aatcatgctt tcaatgggaa ttagcaaaac aaagattttc
    18961 ttccaattta tcacagaagt tctctttgta agtatattta gcttcattgg tgcttacttt
    19021 gcaggtagtg ctgtcagcaa ggtgatggga aatagcattt taaaacaagt taccagtggt
    19081 attgctgaaa aactagctcg agaaggtaag agcgccaatc ttggaggcgg ggctgaagtg
    19141 gatgacttta acaagaccct cactagcctc aatgtacatg tatctcctga tgatatgacc
    19201 aaggtggtca tctttggact tgccattatc atcgtttccg tcctcattgc ttcaatcacg
    19261 ctccttagta agcaaccaaa agacttacta atgggagata acagcaaata agatatcaat
    19321 gagttcagac aaaatcggtc cgtcagctaa gttgacggac cgatttattt tataaacagc
    19381 tagactgact ctcggatgaa atgacgtgag gttcgctttg tcgacttggt cgataaaatg
    19441 aaccgctttg gattggctct gtcgacccag tcgaaaagat aaataacttt tagtttacca
    19501 cgtcgacccg gtggacgaga taaactactt ttggttttct ccgtcagccc ggcggacgaa
    19561 atgaagcaca ttggatgtgg ctcacttgcc tattgttgcc ctcttttttg ctcccaacca
    19621 tactgattgt ttactgattt ttacagttct tttgatgtgc tttcagcttc ttcatggccc
    19681 agtcgtagtg actcgatgtg cagctgacaa agtaggagcc aagggtactc ccaccaaccc
    19741 atttatagat gccctttgaa aacagctctt catttgtaaa ggtttcagcc atggttagca
    19801 ctttttcctg tgattgatga agcaacttga ttgctttttc tagcggtgtc tgttgatgtt
    19861 tttgccaaaa tgccacattc atctcaccat aacttctcca attataagct gctggcaaaa
    19921 acgatttttc gacaccattt tgattggaat gcacccaatc caaaagcaat tgttgccact
    19981 cataaagatg aatgagaaca tctctgaggt ttttatccct cttccaatgc gcctctttct
    20041 ttttttcatc ttttgaaaaa tcaaatggag tctttaactc ttcttctgtt aattgggaaa
    20101 tcaatgactg cagctttgca tattgctgcg tcgctgcact gatcaactca gtcttgctag
    20161 taggtcttac catgttgtgt tctccttttt taataaatca tacaacaaat aacctgacaa
    20221 cctctgtcat atttttagtt ttctctttat ttttgtctca ttttttcttt gatttcacat
    20281 tggcagtcgc aatcgccaca gcgtcctttt cctttgatga tatggtgcat agctgcacct
    20341 gctaaaacta aaatgatgat aaatacaata atcgtggaca taatttctcc tatactgttt
    20401 gacgtgtcag actatctaaa gtgataacct ctactgtttc tttgcgcggt tttctaaaga
    20461 tgaaatagag acccgctgct acaacgagca gagcaaagac agtcactgga gatattcctt
    20521 ttccgtacag caaaacttga ccaaattggt aaatcacaag gctgacatta taagccagta
    20581 gggtttgaaa tgaaatagca atccacgtcc atttagcatt tcccatttcc cgatgaatcg
    20641 caccaatcgc tgcaaaacaa ggagcgcaga gtagattaaa gacaaggaat gagtaagcgg
    20701 aaagtgccgt ataatgctgt tggagattgg tccacaactc tttggtggtc tctgtcgcgt
    20761 ctgtcacttt atacaagatt ccaaaagtag aaatcaccgt ttccttagcc aacaatcccg
    20821 taatagccgc aaccgttgct cgccaattgc caaagccaag agggctaaag atccaagcta
    20881 atccttttcc taaggtggct aga
//
