LOCUS       NZ_PNXQ01000016        47614 bp    DNA     linear   CON 30-JUN-2024
DEFINITION  Paenibacillus terrae strain PIC167 Contig_016, whole genome shotgun
            sequence.
ACCESSION   NZ_PNXQ01000016
VERSION     NZ_PNXQ01000016.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus terrae
  ORGANISM  Paenibacillus terrae
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 1232833)
  AUTHORS   Gomez-Lama,C., Legarda,G., Ruano-Rosa,D., Pizarro-Tobias,P.,
            Valverde-Corredor,A., Niqui,J.L., Trivino,J.C., Roca,A. and
            Mercado-Blanco,J.
  TITLE     Bacillales members from the olive rhizosphere are effective
            biological control agents against Verticillium dahliae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1232833)
  AUTHORS   Gomez-Lama,C., Legarda,G., Trivino,J.C. and Mercado-Blanco,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JAN-2018) Proteccion de cultivos, Instituto de
            Agricultura Sostenible, Av. Menendez Pidal sn, Cordoba, Andalucia
            14004, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2017
            Assembly Method                   :: Megahit v. 1.0.3-29-g707d683
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_000235585.1
            Genome Coverage                   :: 130.81x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005217525.1-RS_2024_06_30
            Annotation Date                   :: 06/30/2024 04:15:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,015
            CDSs (total)                      :: 4,939
            Genes (coding)                    :: 4,759
            CDSs (with protein)               :: 4,759
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 180
            CDSs (without protein)            :: 180
            Pseudo Genes (ambiguous residues) :: 0 of 180
            Pseudo Genes (frameshifted)       :: 50 of 180
            Pseudo Genes (incomplete)         :: 143 of 180
            Pseudo Genes (internal stop)      :: 19 of 180
            Pseudo Genes (multiple problems)  :: 28 of 180
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:51:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 500910
            Orig. end                         :: 548524
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PNXQ01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..47614
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NRPS-like"
                     /product="NRPS"
                     /region_number="5"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX) and not alpha_am_amid)"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..47614
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..>42741
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>42741
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:>22741](-)"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..>22741)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX) and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     gene            complement(85..753)
                     /locus_tag="C1I60_RS19880"
                     /old_locus_tag="C1I60_19920"
     CDS             complement(85..753)
                     /GO_component="GO:0019867 - outer membrane [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009254 - peptidoglycan turnover [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687404.1"
                     /locus_tag="C1I60_RS19880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19920"
                     /product="3D domain-containing protein"
                     /protein_id="WP_137063275.1"
                     /transl_table=11
                     /translation="MKHLKRIGKTMKFAVLAAAIAGLAQTAGVADAASLHTAKEGDTFF
                     LLAQRYGVSVDNLQKDNPDLAASNIYAGVQIKVPVENKVKAASDSKPQLLSDKAPAGDG
                     QQVEAWGKTFNYSKVVDVKATAYSAATSENGKWGAVDYFGNPLKLGTIAVDPNVIPLGT
                     KVLVTGYSHPGLPDHSFVAVARDKGSAITGKRIDIFIPGSPSFVSDFGFQNVKLYVIDK
                     "
     regulatory      complement(761..933)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(1182..1904)
                     /locus_tag="C1I60_RS19885"
                     /old_locus_tag="C1I60_19925"
     CDS             complement(1182..1904)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371435.1"
                     /locus_tag="C1I60_RS19885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19925"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_134914763.1"
                     /transl_table=11
                     /translation="MITVKQLRKSFGKNEILKGIDIDIAKGEVVVVIGPSGSGKSTFLR
                     CMNLLEQPTDGEILFEGEPITARGHNINATREKMGMVFQHFNLFPHKTVLQNLTLAPTQ
                     VRGQSAKEAEKIALELLRTVGLEDKKDTYPNQLSGGQKQRIAIARALAMQPHVMLFDEP
                     TSALDPEMVGEVLDVMKKLAEGGMTMVIVTHEMGFAREVGDRIIFMDNGQIVEQGTPEQ
                     VFGTPSHDRTRDFLAKVL"
     gene            complement(1891..3354)
                     /locus_tag="C1I60_RS19890"
                     /old_locus_tag="C1I60_19930"
     CDS             complement(1891..3354)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371436.1"
                     /locus_tag="C1I60_RS19890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19930"
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="WP_137063276.1"
                     /transl_table=11
                     /translation="MKKAYRFTALILTAVILLLAGLPMLTAYGTEAKTQPKLVLGMSAD
                     FPPYEFHKVINGKDTIVGFDVDIANEIAKDLGAELVIEDMSFDSLLPALQSGRVDLVLS
                     GMTPTDERKKSIDFSDVYYHSKQVIMVRPEDKDKYSTMAALKGEKIGAQKGSIQEEIAQ
                     KVPNASVTSLDKISDLVLQLRTQRVNAVVIEDTVAKGYTLDGTVTLAKAVPEDEGAETA
                     VGIRKGNAELLASVNKTLARLKADGSIEKFSTEASALSADRQVSSNNIVDIFWKYRSFY
                     ATGIGYTLLLSALGVLFGFIIGLIISLLRMSGVRIIEWLGTAYVEVLRGTPMLVQLMII
                     HYGVALTLGVNFTPLQSGIITLSLNSSAYLAEIFRAGIQAVDRGQMEAARSLGMGRGKA
                     MRHVILPQAFKSVLPAIGNEFITIIKESSIISTIGMVDIMYQAQVIKNITYEGLSPFVI
                     AAAIYFVMTFSLSKLLGLWERKLRASDHR"
     misc_feature    complement(3415..3428)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.49"
                     /tool="antismash"
     gene            3503..4681
                     /locus_tag="C1I60_RS19895"
                     /old_locus_tag="C1I60_19935"
                     /pseudo=""
     CDS             3503..4681
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371437.1"
                     /locus_tag="C1I60_RS19895"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19935"
                     /product="M20 family metallopeptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGFKQTIQHTIEQYAQRFKNISLYIGANPELGNEEFLATARLKEE
                     LAFHGFEVQTPVLGIETAFIATYIAAKPGPVIAFLAEYDALKGLGHACGHHLICMMSTG
                     AAVGLKSVIDEIGGEVRVYGTPAEETRGAKVPMAAAGLFDDCDIALMTHPYDRYEKSGK
                     SLAIDAVQFEFFGQSAHAAANPHEGINALDAVIQTFNGINAFRQ"
     gene            4742..5812
                     /locus_tag="C1I60_RS19900"
                     /old_locus_tag="C1I60_19940"
     CDS             4742..5812
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820720.1"
                     /locus_tag="C1I60_RS19900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19940"
                     /product="hypothetical protein"
                     /protein_id="WP_137063277.1"
                     /transl_table=11
                     /translation="MNHMSSFWVLFIVVDIIILWFFFRALYRRNRENRKTRRRNAFFLS
                     SPSPSSLEQGRHKEIIELMQLLERSIPASYAHSVRRRVMDAHPHLTDQEYDWRWNELKR
                     YFMLCAIMNRVPMFSPDVDELWHEMLMFTREYQQFSEAFFGRMLHHAPHASSQPMPDER
                     AWFDWLYVECFGWNRYSASLWGTFFNHPLPNNELAHYYKLTASGQPAGDRWNTQEDMSI
                     SQQAQQAVQRIVDHLRNRVNEAVDDPDGRLLPKVNYLQIDYLLLAVVWYSWYQPHQFAL
                     HMHPDATGSAALASSSGCSSASGCSNWDTHDSNHHSCHGSSHDGDSSHHDSGDSGGSHS
                     SCSSSSSCGSSCGGGD"
     gene            complement(5926..7368)
                     /gene="glgA"
                     /locus_tag="C1I60_RS19905"
                     /old_locus_tag="C1I60_19945"
     CDS             complement(5926..7368)
                     /EC_number="2.4.1.21"
                     /GO_function="GO:0004373 - glycogen (starch) synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="glgA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432522.1"
                     /locus_tag="C1I60_RS19905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19945"
                     /product="glycogen synthase GlgA"
                     /protein_id="WP_137063278.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-14,
                     bitscore: 50.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILFAAAEAHPFIKTGGLADVIGALPKALRQAACDVRIILPKYT
                     GIPDTYKKSLRPVTVKHVSVGWRDQYCGVEELTLDGIKVYFIDNEYYFGRDGIYGYMDD
                     GERFSFFNRAILEVLPDLNFQPDILHCHDWHTAMVPLLLNANYRHLPFYVDIRTVFTIH
                     NLLYQGDFPYEVLTELLNLDSSYFTPEGVEYHGRLNFMKGGLTYSDHVTTVSPTYAEEI
                     QTEFYGYGLEGLLRKLGAQGRLSGIVNGIDIKSYNPATDHRIYTKYRTSLAKKKENKIG
                     LQKELGLPVRPDVPLIAMVTRLVDMKGLNLVTRVLDEIMYDDDIQFVVLGTGDPAFEHW
                     FREAAGRYPLKMSAQLGFNEPLSRKIYAASDMYLMPSRFEPCGISQLLALRYGSIPIVR
                     ETGGLNDTVHAYNESTGEGNGFSFKNYNAHDMLHTIRRAVDFYRQPEHWSKLTSTAFAG
                     EYSWDVSAGAYLDIYRSLTGNE"
     cand_cluster    5966..47614
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5966..47614
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[<25965:27614](-)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(<25966..27614)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     gene            complement(7422..9344)
                     /gene="glgB"
                     /locus_tag="C1I60_RS19910"
                     /old_locus_tag="C1I60_19950"
     CDS             complement(7422..9344)
                     /GO_function="GO:0003844 - 1,4-alpha-glucan branching
                     enzyme activity [Evidence IEA]"
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0043169 - cation binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281514.1"
                     /locus_tag="C1I60_RS19910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19950"
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="WP_137063279.1"
                     /sec_met_domain="CBM_48 (E-value: 2.4e-18, bitscore: 62.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 4.2e-14, bitscore:
                     48.9, seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase_C (E-value: 2.3e-20,
                     bitscore: 68.9, seeds: 246, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDQTLPQQAVSPEDIYLFHEGTLYHSYRSLGSHLTVENGEQGVR
                     FTVWAPHALHVGLATDCNNWNGEQDSLYRVPESGFWSRFFPGISQGTFYKYDITGANGE
                     RFLKADPYAVRAELRPATASVVASLEGYVWNDAAWRRKRREPYGKPLHIYELHLGTWKQ
                     QEDATFYTYREMAELLVPYVTEMGYTHIELMPLSEHPYDLSWGYQLTGYFALTSRYGEP
                     QDFMYLVDRCHQAGIGVLMDWVPAHFAKDAHGLRMFDGSPLFEYADPLIAEKPGWGTLT
                     FDYSKPEVRSFLISNALFWMDVYHIDGLRVDAVTSMLRLDFEKQDGQYRFNSKGGIENE
                     EAIAFLQQLNETVFRYYPYALMMAEESSAWPMVTSPVSDGGLGFNYKWNMGWMNDTLDY
                     IETDFDQRPERHNLLTFPIAYAYSENFTLPLSHDEVVHGKKSLLDKMPGSYEQKFAGLR
                     ALLGYQITSPGKKLLFMGGEFGQFTEWKDEEQLDWFLLDYDSHRSLHAFTKALNHLYIQ
                     EKALWELDHSWDGYQWIEAEDRGQSVITYLRKGKKPGDTVVVLINFQPVPRENYRIGLE
                     KAGIYIELLNSDHSDFGGTGQLNTEVLRTAKIPCHGQLHSLEVTLPPLSVVILKKAPRR
                     ARKAD"
     gene            9582..10808
                     /locus_tag="C1I60_RS19915"
                     /old_locus_tag="C1I60_19960"
     CDS             9582..10808
                     /EC_number="2.7.7.27"
                     /GO_function="GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432524.1"
                     /locus_tag="C1I60_RS19915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19960"
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="WP_137063280.1"
                     /transl_table=11
                     /translation="MFNKECIAMLLAGGEGRRLAPLTSTIAKPAVPFGGHYRIIDFPLS
                     NCVNSDIDTVGVLTQYEAESLHEHIGDGTPWNLTKTNDKGVTLLPSYNTDNAEYLGTAD
                     AIHKNIEYIDSQNPEHVLILSGDHIYYMNYREMLNYHKEKVAAATISVMEVPWDEAHRF
                     GVMSADEELRVTEFAEKPEKPESNLASMGIYLFKWDYLRKYLVEDAEDEQSSHDFGKDI
                     IPKMLADQESLYVYEFQGYWKDVGTVKSLWDSHMDLLQKNCAIDLQRTDWPMYTRERRT
                     RLSAHKLSNYKTEPLDSLLHDSCQVEGQIERSVVFSGVEVGKGSAIKESIIMPNTRIGR
                     NVHIEHAIIGEGAVIRDGAVIKGNPSEIMVIGPNETIFGKMAVRPQTARMLKEAYERNT
                     RLRAEGFTS"
     gene            complement(10883..12322)
                     /locus_tag="C1I60_RS19920"
                     /old_locus_tag="C1I60_19965"
     CDS             complement(10883..12322)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371442.1"
                     /locus_tag="C1I60_RS19920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19965"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_137063860.1"
                     /transl_table=11
                     /translation="MIKKGIGRQIVLHYFFVVFLALLLVEVIFMIVIRAYYYDTIYKHV
                     ESRIQSVSEFAPKFKEPGQSLQSYLLNTFSLGDTELQLLDEKGNVIDNSTNFAAETSVQ
                     TSDVTQALAGDTGSWIGKQPGTGQQVMAVSKKLDNIVGDQVYIVRYTTSLEKVNDKLFT
                     ITLFSVGIMVAVLVIVFVVSTGLANSIVRPINNIRDVSAQMAQGRFDARIKGDYRFELG
                     ELASTLNYMAQEIARTNQIKDDFISSISHELRTPLTSIKGWSETLNSGGYDPEETRIGM
                     QIISKETDRLIGLVEEILDFSKLEQDAMKLVMGTVDLRELLQEIMLNVWAKAEMKQIKL
                     QLDSEETAYLVHGDGNRLKQVFLNIADNAIKFSHENSIIFLSLQRIGDNIEVSVQDTGI
                     GISEENLARVRERFFQVDHQNGGTGLGLAISQQFVERHQGQMLIKSELGAGTTITVSLP
                     ALQDEQPIEPLQLTEGYGTES"
     gene            complement(12319..13017)
                     /locus_tag="C1I60_RS19925"
                     /old_locus_tag="C1I60_19970"
     CDS             complement(12319..13017)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820715.1"
                     /locus_tag="C1I60_RS19925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19970"
                     /product="response regulator transcription factor"
                     /protein_id="WP_025682710.1"
                     /transl_table=11
                     /translation="MSKVLIMEDEESIRSFIVINLKRNGFEVLEASDGHEALNILNTVR
                     DIDIALLDVMVPGMDGFEVCRRIRETNERIGIIFLTAKVQEQDKVYALSVGADDHVSKP
                     FSPTELIARIQSLLRRVNVHRETAAKVSFQSGPFTLDLIAKQFKKNGQLIELTPTEFSL
                     IQFFLEKENTPLSRDVLLDHVWGKEYMGDPKIVDVNIRRLRQKIENNPSEPAFLQTVWG
                     HGYKWKGQAQ"
     gene            complement(13019..14353)
                     /locus_tag="C1I60_RS19930"
                     /old_locus_tag="C1I60_19975"
     CDS             complement(13019..14353)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687406.1"
                     /locus_tag="C1I60_RS19930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19975"
                     /product="hypothetical protein"
                     /protein_id="WP_137063281.1"
                     /transl_table=11
                     /translation="MKGTAREVKMMLLRMLTGCCASLLLVGFLSGCNVISDPISLMQAP
                     MMSDEKQQLNGAVVTQLGMVQPLRPNDPDDPTPIRTGDLNNDGTDEAVLFYETPDESVK
                     IHGALFEDQNGTWVKKLTFDGEGTVLESFKLVDVTNDGTLDIVAGFSSGDSSDGGDQKG
                     LIVYSYTGGTLEKIYATGYTDFVVDDFNHNKMDLNGDNLNDLTIILLRRNEFFTVKTFQ
                     FSGGTFKEIGSLDLDSQALSIYNVVAGKVAEGRQGIIIDTKIAQTTTVSNVIVMDHGKL
                     KKLDLMDVTFKDATITSGDVDGDGILEFGNLEKPKGWSNRPLDEVPYFVSFYQWDGAKG
                     TIFKQQQYRDSNDQVYFRLPKELHGKVTIDPKVSKKDSYLRFILDNTDKTIAEIKYFSL
                     SQWERNNEGYSQLWRTNAQVIGIKRSSELEPRKTIKNKLGERQVE"
     gene            complement(14350..15075)
                     /locus_tag="C1I60_RS19935"
                     /old_locus_tag="C1I60_19980"
     CDS             complement(14350..15075)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371445.1"
                     /locus_tag="C1I60_RS19935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19980"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_137063282.1"
                     /transl_table=11
                     /translation="MIRIQKLTKQVGPERTPLLRGINAEIHPGELIAVVGPSGSGKTTL
                     LRCLALQEPWEEGSLMVDGQDVLKSGWTGKMKIKREWAYLEQNPHLNMNRTALKNVLIG
                     RSGQTPLWRMVTGMVRSDDYMGAMDVLEDLGLLDKAHDKCDKLSGGERQRVATARALVH
                     GAKVILADEPVNGLDPTSADHVMDTFRKLCSDERVTVITVLPLEIAERFASRIWGLNGG
                     ELVFDIQGRRLTQVEKNKL"
     CDS             complement(15158..>15924)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=2
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281508.1"
                     /locus_tag="C1I60_RS19940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19985"
                     /product="MFS transporter"
                     /protein_id="WP_252361802.1"
                     /transl_table=11
                     /translation="RNISFYGMSYGLGFALGPLGLWLLDYGMLVPFAALALLCLLILLL
                     VLMKLPDSRPEKLETGARPARRFRRSYSWAWYALLPAFLYGYMEASLNSNFPVYGLRIG
                     FHTDEIAALLPFVSLGGLVLQLPLGIWSDRWGRKKVLISVGIAGGLIFMLMPWSGNHFM
                     LTLVLLAVAGGLVGSFFSLGLAYAADLLPKSLLAAANVLASFHFNLGSVIGPNISGALL
                     DYGTQGSMFLVLGGSYVVFGLLGLLFQKRISTA"
     gene            complement(15158..>15926)
                     /locus_tag="C1I60_RS19940"
                     /old_locus_tag="C1I60_19985"
     assembly_gap    15927..15936
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="align genus"
     gene            complement(<15937..16304)
                     /locus_tag="C1I60_RS25900"
                     /pseudo=""
     CDS             complement(<15937..16304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427726.1"
                     /locus_tag="C1I60_RS25900"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSSSMRVHYFILIAVIVVAGLCQGLLLPILSISLEQMGVSSFLNG
                     MNAAALYIGSFAMTLVAERTLGWLGFKKLMAGGLVLVLFTLLLFPLIPDIRVWFVLRLL
                     VGIGDSALHYSAQLWILL"
     gene            16745..17662
                     /locus_tag="C1I60_RS19945"
                     /old_locus_tag="C1I60_19990"
     CDS             16745..17662
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820711.1"
                     /locus_tag="C1I60_RS19945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19990"
                     /product="hypothetical protein"
                     /protein_id="WP_044648480.1"
                     /transl_table=11
                     /translation="MSYQIKIDTSPIYELLGSFMAYVTKKWVHDMDLGHEWIDKVDARL
                     QNEVRTELATAQDCPFSDYDALYVWALLRPESDEISDYIAYLDHGPDEDMFELIVPHVP
                     FLTFEESLRIRKVYAPLLKLWDRDYFRAMESELRVLAEEDAAEKRMLLNKMEPEALVEY
                     ATAGLIVPHMEDLDTVVLFPVVHNRPINSYCFYTRMLLIQYPVDVPEESEEEPPTLLLR
                     LTRAVNDPQRLRILRYVAQGPKSLEDMRHDLSRLEDTLMSDMMILRVAGLLRIHIGRYH
                     KEKFSIRPDGAADLQVFLESYIGL"
     gene            17727..18491
                     /locus_tag="C1I60_RS19950"
                     /old_locus_tag="C1I60_19995"
     CDS             17727..18491
                     /EC_number="3.1.3.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820710.1"
                     /locus_tag="C1I60_RS19950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_19995"
                     /product="HAD family hydrolase"
                     /protein_id="WP_137063283.1"
                     /sec_met_domain="HAD_2 (E-value: 7.1e-18, bitscore: 61.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYPKQHILFDLDDTLVHCNKYFDLILNHFFDLLQEWFAAHNLTK
                     NTIREKQIEIDVAGVHQVGFASEHFPQSLIDTYHFFSEQFGRRTDPREEQELRSLGRSV
                     YEQEIEPYPGMVETLNSLQKAGHSLHLYTGGEQVIQEKKIEQMKLANYFDDRIYIRQHK
                     NVEALEEIIQMNRFDRSITWMIGNSLRTDVSPALAAGIHAVYLKQPKEWVYNMVELQKN
                     VNSVMYTIQKLTEVPRVIHESIQLHQQKRTLG"
     gene            complement(18699..19973)
                     /locus_tag="C1I60_RS19955"
                     /old_locus_tag="C1I60_20000"
     CDS             complement(18699..19973)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281505.1"
                     /locus_tag="C1I60_RS19955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20000"
                     /product="hypothetical protein"
                     /protein_id="WP_137063284.1"
                     /transl_table=11
                     /translation="MDAIKLASTYFFGTEDYILSNSMIATVTFKRRIDAEKLFVSYRSL
                     IMDNPLLQAKRVEQFEKDTFVWGRFSQEELEQFLEAEKMKLSQYFTEEEVLAQYRPTNA
                     RLPFRIYPINEYTMIFAMNHAVANGLSLVFWIKRWLEYYSGEPDSDPKNKAAKGDISKD
                     RLLRMKRRFSAFMWMPVFVAGFMSRVRGKGTGAGETVDLSYGRRPEQGGGYVKKSYRFS
                     KEETGEILRRCRSLKMTLTEYICYRMTDGLLQHAPDKQRVFVSMPMDLKFLHNYSPETM
                     HGNYVASLPMQFFRDGNLEKQVKSAFKWFKRGVPYALSLFFASFSNSYRKYKQQCLELV
                     MKTMPERFPLWNFTITLSNLGVISYPIMEEWVDSIYFSIKNQSLLLTTATLSGRLMMEV
                     SLLENLYDSEEVFGLFDRILSVEHL"
     CDS             complement(20001..>22741)
                     /NRPS_PKS="Domain: AMP-binding (0-315). E-value: 6e-83.
                     Score: 270.6. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24960_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (424-486). E-value: 1.7e-20. Score:
                     65.0. Matches aSDomain: nrpspksdomains_C1I60_RS24960_PCP.1"
                     /NRPS_PKS="Domain: NAD_binding_4 (546-792). E-value:
                     2.7e-48. Score: 156.2. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24960_NAD_binding_4.1"
                     /codon_start=2
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="C1I60_RS24960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_212734492.1"
                     /sec_met_domain="AMP-binding (E-value: 1.8e-102, bitscore:
                     339.0, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-14, bitscore:
                     50.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 5.1e-47, bitscore:
                     156.2, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.6e-08, bitscore:
                     28.3, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YPEERIHYMLEDSSASIVLTQKHLRDKLTYHGAIMDLDGESLRHI
                     EPDGSANPEPVNKPEDLSYIIYTSGSTGKPKGVMVEHRGIINLQYFFQEQWGVDGSDRM
                     LQFASSSFDASVWEMFTILLGGGTLYLVSRDIINNLNEFARFMNENQITIALLPPTYLA
                     GIEPDRLPTLKKLVTGGSAITKELVMRWKDSVEYMNAYGPSESSVIATAWTYREEDMGY
                     ASVPIGKPIANTRIYIMDRNQKLLPLGAAGEMCIAGDGLARGYLHRPELTAEKFVANPY
                     EGGEKLYRTGDLVRWLPDGNIEFLGRIDDQVKIRGFRIELGEIEAQLMKHPLVREVAVI
                     AREDKQGEKYLAAYFTAEGEPGAEELREQLMQELPDYMVPSSFMQLDDMPMTPSGKMDR
                     KALPEPEWQGSDHTVSSPRNDVDLKIQKVWQEILGIESIGIDEHFFRLGGNSIKAIQVV
                     SRLALDFEVGINDIFQYPTIRALADNIKYSKDRLKQFVYALREAAASGENGVPGVVWKM
                     RESLKEYRKKNQGYENIDLSERADYRNVLLVGGTGYLGIHILFQLLQNTEYKVYVPVRG
                     TNDEEALERLWAKLKFHFGLELDGHNVWKDRVCVFCGDLTEDCFGLSRERYEDLAGSID
                     AIINSAANVKHFGHYSEFQAVNVEGNERLIKFAGTGKKKTYNFVSTTSVGSGWIEDQSS
                     IMFTEYDCNVEQSSDNYYVMTKLEAEKEIVKARQQGLDSNVFRVGNLVFDSNSGIFQEN
                     ISDNAFYSLVKSMITLGRVPAIQDKTMNFSFVDEVAKAVVLLFDRKNLINETYHLFNSH
                     QVSMIAFAKLLKQADINVKPMPVEDFTEYMFEKYDEPETEQEVARILVHSNVFFEGASK
                     TLFMTMNKKTDGILQALGFEWSRLDGQKVKLMMDHVKKVGFM"
     gene            complement(20001..>22743)
                     /locus_tag="C1I60_RS24960"
     aSDomain        complement(20364..21101)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24960_NAD_binding_4.1"
                     /evalue="2.70E-48"
                     /label="C1I60_RS24960_NAD_binding_4.1"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="792"
                     /protein_start="546"
                     /score="156.2"
                     /tool="antismash"
                     /translation="LVGGTGYLGIHILFQLLQNTEYKVYVPVRGTNDEEALERLWAKLK
                     FHFGLELDGHNVWKDRVCVFCGDLTEDCFGLSRERYEDLAGSIDAIINSAANVKHFGHY
                     SEFQAVNVEGNERLIKFAGTGKKKTYNFVSTTSVGSGWIEDQSSIMFTEYDCNVEQSSD
                     NYYVMTKLEAEKEIVKARQQGLDSNVFRVGNLVFDSNSGIFQENISDNAFYSLVKSMIT
                     LGRVPAIQDKTMNFSFVDEVAKAV"
     aSModule        complement(20364..24239)
                     /complete
                     /domains="nrpspksdomains_C1I60_RS24965_Condensation_DCL.1"
                     /domains="nrpspksdomains_C1I60_RS24960_AMP-binding.1"
                     /domains="nrpspksdomains_C1I60_RS24960_PCP.1"
                     /domains="nrpspksdomains_C1I60_RS24960_NAD_binding_4.1"
                     /locus_tags="C1I60_RS24960"
                     /locus_tags="C1I60_RS24965"
                     /monomer_pairings="X -> X"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     aSDomain        complement(21282..21467)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24960_PCP.1"
                     /evalue="1.70E-20"
                     /label="C1I60_RS24960_PCP.1"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="486"
                     /protein_start="424"
                     /score="65.0"
                     /tool="antismash"
                     /translation="IQKVWQEILGIESIGIDEHFFRLGGNSIKAIQVVSRLALDFEVGI
                     NDIFQYPTIRALADNIK"
     CDS_motif       complement(21765..21830)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24960_0003"
                     /evalue="3.10E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="325"
                     /protein_start="303"
                     /score="41.4"
                     /tool="antismash"
                     /translation="FLGRIDDQVKIRGFRIELGEIE"
     aSDomain        complement(21795..22739)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24960_AMP-binding.1"
                     /evalue="6.00E-83"
                     /label="C1I60_RS24960_AMP-binding.1"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="315"
                     /protein_start="0"
                     /score="270.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YPEERIHYMLEDSSASIVLTQKHLRDKLTYHGAIMDLDGESLRHI
                     EPDGSANPEPVNKPEDLSYIIYTSGSTGKPKGVMVEHRGIINLQYFFQEQWGVDGSDRM
                     LQFASSSFDASVWEMFTILLGGGTLYLVSRDIINNLNEFARFMNENQITIALLPPTYLA
                     GIEPDRLPTLKKLVTGGSAITKELVMRWKDSVEYMNAYGPSESSVIATAWTYREEDMGY
                     ASVPIGKPIANTRIYIMDRNQKLLPLGAAGEMCIAGDGLARGYLHRPELTAEKFVANPY
                     EGGEKLYRTGDLVRWLPDGNIEFLGRIDDQVKIR"
     CDS_motif       complement(21912..22001)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24960_0002"
                     /evalue="3.10E-17"
                     /label="NRPS-A_a6"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="276"
                     /protein_start="246"
                     /score="54.6"
                     /tool="antismash"
                     /translation="PLGAAGEMCIAGDGLARGYLHRPELTAEKF"
     CDS_motif       complement(22494..22553)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24960_0001"
                     /evalue="3.10E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="C1I60_RS24960"
                     /protein_end="82"
                     /protein_start="62"
                     /score="34.9"
                     /tool="antismash"
                     /translation="SYIIYTSGSTGKPKGVMVEH"
     assembly_gap    22744..22753
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="align genus"
     CDS             complement(<22754..25953)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: PCP (22-89). E-value: 4.6e-24. Score:
                     76.4. Matches aSDomain: nrpspksdomains_C1I60_RS24965_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (99-401). E-value:
                     3.5e-156. Score: 513.0. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24965_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (405-558). E-value: 1.7e-47.
                     Score: 153.0. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24965_TIGR01720.1"
                     /NRPS_PKS="Domain: Condensation_DCL (571-870). E-value:
                     2.4e-114. Score: 373.5. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24965_Condensation_DCL.1"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C1I60_RS24965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_252361803.1"
                     /sec_met_domain="PP-binding (E-value: 1.2e-11, bitscore:
                     41.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 1.1e-87, bitscore:
                     289.9, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPEPDLSVNATEEYVAPRDKIEEILAEIWGKVLKVERVGIKDHF
                     LNLGGDSIKAIQIVSKLHDYKLKLQLKELFDHPVIEQLSAYVQSVEHTAFQGMVTGEIM
                     LTPIQSWFFEQPFAAKHHFNQSVLLHRKQGFDERMLRKVFDRLVEHHDALRIVMREKAG
                     QVVLFNRGTEGELYSLEVKDLTNDDIYDSSVKEEAAQLQSRMDLECGPLMQAGLFKTKD
                     GDYLCVSIHHLVVDGISWRILFEDISTGYRQAEQGEEVTFRGKTDSFLAWSEQLYTYAS
                     SGELLQEITYWSELEQNEIKPIPKDHSVHGRTYMDSDHIEIVLDEFQTAKLLREVNKAY
                     NTEINDVLLTALGEAIREWTGEDKVLVNLEGHGREEIIQDMDISRTVGWFTAQYPVILD
                     MEGVKNVSSRLKAVKESLRRIPQKGIGYGILKYQTFPRDEEILRFNLHPEISFNYLGQF
                     DQDIDTDIFTISDVLTDETVSPDMQRPYCLDINGRVTDGKLRLSFTYHKHEYEKATLIT
                     VAEGFKRNLEQIIEHCASQEYTELTASDVSSSNITTAEVEEVYRAMGDSKPNITDIYTL
                     TPMQSGMLYHFLREQNSHAYFEQAVISLEGEIDRSLFERAFQQMIQRHDILRTAFVYEK
                     VEKPVQVVLKDRPAEMFFEFISFLTEEEKENHLQAYLDKDREKGFDLTREPLIRFALVR
                     MNAHSYRFILSFHHIIMDGWCLGIVFKELLEIYSALHKGSIPQLGTVYPYHQYIQWLEQ
                     RNDRETGAYWENYLTEYEQPALLPKIKSGIANPGYIQEEYDFTINKEMKASLERIAREN
                     GATLSTVIQAVWGILLQRYNNTQDVVFGTVVSGRPAEIQGVEQMVGLFINTIPVRVRAE
                     KEESFSDLVAKLQQEAWASERHHYYPLAEIQSRTAHGGGLVQNLLAFENYPIEEAVKGQ
                     GDHGTDLRILSTKVSEQTNFDFNFIVVPENDLQIKFRYNSLAYDRGFMERVAGQIKMII
                     CEIIRYPKMRIEDIEIVPEEERSTLVRGFNHTEAEYPKDQTIHGLFEERAEQRADHLAL
                     VWGEQTLTYRELNEQANRL"
     gene            complement(<22754..>25955)
                     /locus_tag="C1I60_RS24965"
     CDS_motif       complement(23187..23303)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0012"
                     /evalue="2.90E-12"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="922"
                     /protein_start="883"
                     /score="38.9"
                     /tool="antismash"
                     /translation="QQEAWASERHHYYPLAEIQSRTAHGGGLVQNLLAFENYP"
     aSDomain        complement(23343..24239)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24965_Condensation_DCL.1
                     "
                     /domain_subtypes="Condensation_DCL"
                     /evalue="2.40E-114"
                     /label="C1I60_RS24965_Condensation_DCL.1"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="870"
                     /protein_start="571"
                     /score="373.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="DIYTLTPMQSGMLYHFLREQNSHAYFEQAVISLEGEIDRSLFERA
                     FQQMIQRHDILRTAFVYEKVEKPVQVVLKDRPAEMFFEFISFLTEEEKENHLQAYLDKD
                     REKGFDLTREPLIRFALVRMNAHSYRFILSFHHIIMDGWCLGIVFKELLEIYSALHKGS
                     IPQLGTVYPYHQYIQWLEQRNDRETGAYWENYLTEYEQPALLPKIKSGIANPGYIQEEY
                     DFTINKEMKASLERIARENGATLSTVIQAVWGILLQRYNNTQDVVFGTVVSGRPAEIQG
                     VEQMVGLFINTIPVRVRA"
     CDS_motif       complement(23352..23447)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0011"
                     /evalue="3.40E-22"
                     /label="C5_DCL_263-294"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="867"
                     /protein_start="835"
                     /score="70.9"
                     /tool="antismash"
                     /translation="DVVFGTVVSGRPAEIQGVEQMVGLFINTIPVR"
     CDS_motif       complement(23688..23726)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0010"
                     /evalue="8.10E-03"
                     /label="C4_DCL_171-183"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="755"
                     /protein_start="742"
                     /score="9.1"
                     /tool="antismash"
                     /translation="PYHQYIQWLEQRN"
     CDS_motif       complement(23772..23837)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0009"
                     /evalue="1.20E-12"
                     /label="C3_DCL_135-156"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="727"
                     /protein_start="705"
                     /score="40.1"
                     /tool="antismash"
                     /translation="FHHIIMDGWCLGIVFKELLEIY"
     CDS_motif       complement(24054..24173)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0008"
                     /evalue="1.40E-18"
                     /label="C2_DCL_024-062"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="633"
                     /protein_start="593"
                     /score="59.1"
                     /tool="antismash"
                     /translation="HAYFEQAVISLEGEIDRSLFERAFQQMIQRHDILRTAFVY"
     CDS_motif       complement(24195..24233)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0007"
                     /evalue="1.40E-04"
                     /label="C1_dual_004-017"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="586"
                     /protein_start="573"
                     /score="14.6"
                     /tool="antismash"
                     /translation="YTLTPMQSGMLYH"
     aSDomain        complement(24279..24737)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24965_TIGR01720.1"
                     /evalue="1.70E-47"
                     /label="C1I60_RS24965_TIGR01720.1"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="558"
                     /protein_start="405"
                     /score="153.0"
                     /tool="antismash"
                     /translation="VSSRLKAVKESLRRIPQKGIGYGILKYQTFPRDEEILRFNLHPEI
                     SFNYLGQFDQDIDTDIFTISDVLTDETVSPDMQRPYCLDINGRVTDGKLRLSFTYHKHE
                     YEKATLITVAEGFKRNLEQIIEHCASQEYTELTASDVSSSNITTAEVEE"
     aSModule        complement(24279..25886)
                     /domains="nrpspksdomains_C1I60_RS24965_PCP.1"
                     /domains="nrpspksdomains_C1I60_RS24965_Epimerization.1"
                     /domains="nrpspksdomains_C1I60_RS24965_TIGR01720.1"
                     /incomplete
                     /locus_tags="C1I60_RS24965"
                     /tool="antismash"
                     /type="unknown"
     CDS_motif       complement(24582..24611)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0006"
                     /evalue="3.30E-03"
                     /label="NRPS-E7"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="457"
                     /protein_start="447"
                     /score="10.0"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     CDS_motif       complement(24657..24716)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0005"
                     /evalue="3.90E-10"
                     /label="NRPS-E6"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="432"
                     /protein_start="412"
                     /score="31.9"
                     /tool="antismash"
                     /translation="VKESLRRIPQKGIGYGILKY"
     aSDomain        complement(24750..25655)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24965_Epimerization.1"
                     /evalue="3.50E-156"
                     /label="C1I60_RS24965_Epimerization.1"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="401"
                     /protein_start="99"
                     /score="513.0"
                     /specificity="E activity: active"
                     /specificity="Active site motif: HHLVVDG"
                     /tool="antismash"
                     /translation="TGEIMLTPIQSWFFEQPFAAKHHFNQSVLLHRKQGFDERMLRKVF
                     DRLVEHHDALRIVMREKAGQVVLFNRGTEGELYSLEVKDLTNDDIYDSSVKEEAAQLQS
                     RMDLECGPLMQAGLFKTKDGDYLCVSIHHLVVDGISWRILFEDISTGYRQAEQGEEVTF
                     RGKTDSFLAWSEQLYTYASSGELLQEITYWSELEQNEIKPIPKDHSVHGRTYMDSDHIE
                     IVLDEFQTAKLLREVNKAYNTEINDVLLTALGEAIREWTGEDKVLVNLEGHGREEIIQD
                     MDISRTVGWFTAQYPVILDME"
     CDS_motif       complement(24759..24809)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0004"
                     /evalue="1.10E-08"
                     /label="NRPS-E5"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="398"
                     /protein_start="381"
                     /score="27.0"
                     /tool="antismash"
                     /translation="DISRTVGWFTAQYPVIL"
     CDS_motif       complement(25212..25277)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0003"
                     /evalue="3.80E-10"
                     /label="NRPS-E2"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="247"
                     /protein_start="225"
                     /score="32.0"
                     /tool="antismash"
                     /translation="LCVSIHHLVVDGISWRILFEDI"
     CDS_motif       complement(25488..25550)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0002"
                     /evalue="5.10E-04"
                     /label="C2_LCL_024-062"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="155"
                     /protein_start="134"
                     /score="12.5"
                     /tool="antismash"
                     /translation="FDERMLRKVFDRLVEHHDALR"
     CDS_motif       complement(25611..25640)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24965_0001"
                     /evalue="3.20E-04"
                     /label="NRPS-E1"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="114"
                     /protein_start="104"
                     /score="13.6"
                     /tool="antismash"
                     /translation="LTPIQSWFFE"
     aSDomain        complement(25686..25886)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24965_PCP.1"
                     /evalue="4.60E-24"
                     /label="C1I60_RS24965_PCP.1"
                     /locus_tag="C1I60_RS24965"
                     /protein_end="89"
                     /protein_start="22"
                     /score="76.4"
                     /tool="antismash"
                     /translation="EEILAEIWGKVLKVERVGIKDHFLNLGGDSIKAIQIVSKLHDYKL
                     KLQLKELFDHPVIEQLSAYVQS"
     assembly_gap    25956..25965
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="align genus"
     gene            complement(<25966..27614)
                     /locus_tag="C1I60_RS24970"
     CDS             complement(<25966..27614)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (8-305). E-value:
                     7.7e-84. Score: 273.5. Matches aSDomain:
                     nrpspksdomains_C1I60_RS24970_Condensation_Starter.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012873.4"
                     /locus_tag="C1I60_RS24970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="condensation domain-containing protein"
                     /protein_id="WP_212734493.1"
                     /sec_met_domain="Condensation (E-value: 6.8e-47, bitscore:
                     156.0, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 7.3e-20, bitscore:
                     67.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTSVISFKEYPLSSYQKDIWFEQCMYPGKPIYNIGGYVEVKGNL
                     NTAIIRQSMQLLITQNDSLSTRFIDKKGEPYLTFLPEADYEVAFHDFSVKENPNSFCIN
                     WMKNEFLKPFQPEDFYFQFVLLKGAPNTYFILLKVHHLVIDGWGFALLISQMFDNYNKL
                     VQGIGEMNRTVYSYADFISDNQNYLNSPAFLKDRAFWQNKYLTIPEPLLSRGMDVDDGD
                     GDSVWSDRRTLTINKALYNQMIEFCKEEGCSSFHYFLGILFLYFSKICNRNEMVIGVPV
                     FNRSKAKYKQTMGHFANVLPLRISPEKDISFKELIKSIKRELMQCYRHQKMSFGEIYRA
                     VYENSNEKGKLFDISLSFEEQETREALIGAASRIVSMPHHHERNALNLLIWGQEGEADV
                     AVNFDYQIQAFERFIPIENVISHFEYLFAQVMEQSETLISQIEIVPEEERSTLVRGFNH
                     TEAEYPKDHTIQGLFEERAEQRADHPALVWGEQTLTYRELNEQANRLATVLREHGVKPD
                     DIVAIMAERSMEMVIGILGTLKAGGAYLPIDP"
     CDS_motif       complement(25971..26012)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0006"
                     /evalue="3.70E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="548"
                     /protein_start="534"
                     /score="16.9"
                     /tool="antismash"
                     /translation="LGTLKAGGAYLPID"
     CDS_motif       complement(26541..26654)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0005"
                     /evalue="3.40E-06"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="358"
                     /protein_start="320"
                     /score="19.6"
                     /tool="antismash"
                     /translation="RELMQCYRHQKMSFGEIYRAVYENSNEKGKLFDISLSF"
     aSDomain        complement(26700..27590)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_C1I60_RS24970_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="7.70E-84"
                     /label="C1I60_RS24970_Condensation_Starter.1"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="305"
                     /protein_start="8"
                     /score="273.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLVIDG"
                     /tool="antismash"
                     /translation="KEYPLSSYQKDIWFEQCMYPGKPIYNIGGYVEVKGNLNTAIIRQS
                     MQLLITQNDSLSTRFIDKKGEPYLTFLPEADYEVAFHDFSVKENPNSFCINWMKNEFLK
                     PFQPEDFYFQFVLLKGAPNTYFILLKVHHLVIDGWGFALLISQMFDNYNKLVQGIGEMN
                     RTVYSYADFISDNQNYLNSPAFLKDRAFWQNKYLTIPEPLLSRGMDVDDGDGDSVWSDR
                     RTLTINKALYNQMIEFCKEEGCSSFHYFLGILFLYFSKICNRNEMVIGVPVFNRSKAKY
                     KQTMGHFANVLPLRIS"
     CDS_motif       complement(26706..26795)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0004"
                     /evalue="3.40E-12"
                     /label="C5_starter_265-294"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="303"
                     /protein_start="273"
                     /score="38.7"
                     /tool="antismash"
                     /translation="EMVIGVPVFNRSKAKYKQTMGHFANVLPLR"
     CDS_motif       complement(27135..27200)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0003"
                     /evalue="3.10E-08"
                     /label="C3_starter_134-155"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="160"
                     /protein_start="138"
                     /score="26.4"
                     /tool="antismash"
                     /translation="VHHLVIDGWGFALLISQMFDNY"
     CDS_motif       complement(27405..27524)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0002"
                     /evalue="3.50E-10"
                     /label="C2_starter_024-063"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="70"
                     /protein_start="30"
                     /score="32.5"
                     /tool="antismash"
                     /translation="PIYNIGGYVEVKGNLNTAIIRQSMQLLITQNDSLSTRFID"
     CDS_motif       complement(27543..27584)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_C1I60_RS24970_0001"
                     /evalue="8.00E-04"
                     /label="C1_starter_004-017"
                     /locus_tag="C1I60_RS24970"
                     /protein_end="24"
                     /protein_start="10"
                     /score="12.1"
                     /tool="antismash"
                     /translation="YPLSSYQKDIWFEQ"
     regulatory      complement(27748..27837)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    27850..27859
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     misc_feature    complement(28159..28174)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.61"
                     /tool="antismash"
     gene            complement(28291..29301)
                     /locus_tag="C1I60_RS19965"
                     /old_locus_tag="C1I60_20010"
     CDS             complement(28291..29301)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281499.1"
                     /locus_tag="C1I60_RS19965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20010"
                     /product="aldo/keto reductase"
                     /protein_id="WP_137063861.1"
                     /transl_table=11
                     /translation="MEVKTANVAGSLQLRKLGNSDLKLSPLGLGCWQFSNGKGIVGKFW
                     PVLRREDIRQIVQTSLEGGINWFDTAEAYGGGQSEQLLAGTLNEIGGPLAEQANIATKW
                     WPAFRTAGSITATIDERIRHLDQRTIHLYQVHSPYSFASVGAVMNAMAKLVGQGKIKYV
                     GVSNFSAQQIREADRVLREHGLRLVSNQVKYSLLDRRIEQNGILDTAKELGVAIIAYSP
                     LMQGILSGKFHKNPSLVKSIKGPRKWTAAFRDSGLRRSKPLIETLEQLAQQYNVSPTQI
                     ALNWLINAHGENVFAIPGASKVHHAEENVKAMQFTLTAGEIEMVSHVSNQVLRSK"
     misc_feature    complement(29454..29463)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.04"
                     /tool="antismash"
     gene            complement(29662..32049)
                     /locus_tag="C1I60_RS19970"
                     /old_locus_tag="C1I60_20015"
     CDS             complement(29662..32049)
                     /EC_number="5.6.2.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003916 - DNA topoisomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006265 - DNA topological change [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281498.1"
                     /locus_tag="C1I60_RS19970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20015"
                     /product="type IA DNA topoisomerase"
                     /protein_id="WP_137063285.1"
                     /transl_table=11
                     /translation="MKTLIIAEKPDMGRTIAAVMEPRAKNNRTYLEGEKYIVTWAIGHL
                     LGLAEPDAYDAKYKRWNIKDLPIIPEQFKIVPNPKTKDQLKIIGELAKRCNAIVNACDA
                     GREGQYIFALIQQQLKLRQPVKRLWISDLTAESIAAGFERLRDASEFEFLTQAARARSE
                     ADWLIGMNASRAFTTRHNALLSVGRVQTPVLALIHDREKEIEAFQSQTFYDVWAEFKQD
                     QTKYKGAWQGDRLTKPEEAEAIAAAVRGKTGEITKYDTKQTKEYPFKLYDLTLLQREAN
                     AKYSYSAKKTLDVAQALYERHKVISYPRTNSNYVTEQNIDGMHKALRMLGTGPYADLVQ
                     QANPNLVHKQNKAVCNPARVEDHHAILPTLKRPGTLSKEEQNVYDLIIRRFLSHFFPPA
                     EYKMHTVMTQVDKHLFKTSIKELLSLGWKVVLSKADQDKGKKSKAPKKEEEEETDEWTD
                     KKFEIDAGRPVDCIRAEMKEKATQPPKSYTEGTLLKAMESAGKQMENEELREVMKDAGL
                     GTPATRAATIERLKKVGYIEMKGKKILVTDKGKMAIDLIRNAGVDLLASPEMTGQWERR
                     LHQISKGEAAQEKFMDNVKKFTLSIIDKVRQQPPAPANAFGEEARGKRSGSKGATRSGG
                     ASGSGSITTQGAARAPSRRTNNSGEASSPEQVLSSAGGRTASGSVGSSSSTRAARASSA
                     EPLGTSPGQRQTLGSCPRSNCGGSIIEGRKGYGCSHYKQGCGFVVWKEYAGKQITETML
                     KSLLTKGQTQLLSFKRKDGSTVKARIVLNEPGTGQLSVREEN"
     misc_feature    32442..32455
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            complement(32720..34207)
                     /locus_tag="C1I60_RS19975"
                     /old_locus_tag="C1I60_20020"
     CDS             complement(32720..34207)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007130010.1"
                     /locus_tag="C1I60_RS19975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20020"
                     /product="glutamate synthase subunit beta"
                     /protein_id="WP_137063286.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9e-26, bitscore:
                     86.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPTGFMEYTRQLPTDRDPAERIKDWEEFHKHMSEEELRTQGAR
                     CMDCGTPYCHTGMDIMGATLGCPVHNLIPEWNNLVYRGLWKEALDRLHKTNNFPEFTGR
                     VCPAPCEGSCTVGLIGQSVTIKTIEEAIIEKGFEEGWVVPNPPEKRTGKRVAIVGSGPA
                     GLAAAAQLNKAGHSVTVYERADRIGGLLMYGIPSMKLDKKVVQRRVDLLEAEGIQFITN
                     TEIGKDIPTDQLIAEYDAVVLCGGSTKPREFNIEGSDLNGVHYAMDYLNGTIKSYLDSN
                     LEDGNYLSSQGKDVIVIGGGDTGSDCVATSLRHGCRSVTQFGTHAKAPVERDPIANPWP
                     QFPNVYTLDYAQQEAKAIFGEDPREFSIMTTKFVGDENGNLKELHTIQIQRIVDETGRK
                     IYQPVPGTERVFPAQIALIAIGFDGPEQTIVEQIGLETDRRSNVKARYGKYVTNVDKVF
                     AAGDMRRGQSLVVWAINEGREAAREVDKYLMGATVLV"
     gene            complement(34445..34933)
                     /locus_tag="C1I60_RS19980"
                     /old_locus_tag="C1I60_20025"
     CDS             complement(34445..34933)
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820708.1"
                     /locus_tag="C1I60_RS19980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20025"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_137063287.1"
                     /transl_table=11
                     /translation="MSISMIWAMAQNGVIGRDNSLPWRLPRDMAFFKEQTIGKTVLMGR
                     KTWESFGGKSLPKRRNVILTRDQSYLAEGAEVIHSLEEGLQLAAQEELMIIGGAEIYSL
                     FWTHADRLIVTRIDEIFEGDTTFPELDWNGWNVVSETPGVKDERNPYDYRFVVYERTK"
     gene            complement(34953..35747)
                     /gene="thyA"
                     /locus_tag="C1I60_RS19985"
                     /old_locus_tag="C1I60_20030"
     CDS             complement(34953..35747)
                     /EC_number="2.1.1.45"
                     /GO_function="GO:0004799 - thymidylate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006231 - dTMP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thyA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345962.1"
                     /locus_tag="C1I60_RS19985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20030"
                     /product="thymidylate synthase"
                     /protein_id="WP_137063288.1"
                     /transl_table=11
                     /translation="MRNYLELLEDILENGVKKEDRTGTGTLSVFGRQLRFDLSKGFPLV
                     TTKRVHLKSVIHELLWFLRGDTNISYLKENGVTIWDEWADEQGNLGPVYGSQWRAWETT
                     DGQHIDQIANVIEAIKNNPDSRRHIVSAWNVAEIDSMKLPPCHFVFQFYVAGGKLSCML
                     TMRSVDTFLGLPFNIASYALLTHMVAQQCGLEPGEFIWSGGDVHIYSNHMQQVHTQLER
                     DPYPLPQIKILRKPDSIFDYTYEDFTFENYEYHPGIKAPVAI"
     gene            complement(36077..37498)
                     /gene="lpdA"
                     /locus_tag="C1I60_RS19990"
                     /old_locus_tag="C1I60_20035"
     CDS             complement(36077..37498)
                     /EC_number="1.8.1.4"
                     /GO_function="GO:0004148 - dihydrolipoyl dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /GO_process="GO:0051068 - dihydrolipoamide metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="lpdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820706.1"
                     /locus_tag="C1I60_RS19990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20035"
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="WP_137063289.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5e-70, bitscore:
                     232.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVGDASLDIDTLVIGAGPGGYVAAIRAAQLGQSVLIVDQSELGG
                     VCLNRGCIPSKALISAAHQYEAAQHGESFGITAENVKVDFAKTQEFKNSVVKKMTGGVS
                     GLLKGNKVEVFNGECMFINENEARVFNEHESPRYRFKNAIIATGSRPIELKPFPFGGRI
                     LSSTEALNLPEIPKSLIVIGGGYIGAELGQMYSKFGSKVTIIEGMDTVLPGFDKDMTSI
                     VAKSMKKTGIEIFTGAKAESAEQTDKDVTVKFSVNGESKEVTADYLLVTVGRRPNTDGE
                     LGLDLIGVELDERGMVKVDHQGRTSIPHIFAIGDIVAGLALAHKASYEGKVAAEAIAGE
                     PSVVDYKCIPAVVFTDPECSSVGYTETQAKEKGHNVKVGKFSYGANGRAVSLNATEGFV
                     KIVADADTGLVLGTQIVGLEASNLIAELGLAIEMGATLEDISLTIHAHPTLGEIVMEAA
                     EVVLGHPIHALAPRR"
     misc_feature    complement(37501..37518)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
     CDS             complement(37502..>38465)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009589180.1"
                     /locus_tag="C1I60_RS19995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20040"
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_252361804.1"
                     /transl_table=11
                     /translation="PAATPAATNKDVLATPSVRKFAREQGVNIAQVSGSGKNGKITRED
                     VEAFKNGGGQAVAPAAKETSKAQEPAKKEAKAAAPSAPAADPRAEEERVPFKGIRKAIS
                     NAMVKSAYTAPHVTIMDEVDVTELVAFRTRMKPIAEKKGTKVTYLPFIVKALVAASRQF
                     PALNASIDEEANEIVYKKYYNIGIATDTDNGLIVPVIKDADRKSIWMIADSIRDLAVRG
                     RDGKLAANEMRGSTISISNIGSAGGMFFTPIINFPEVAILGTGRISEKAVVKNGEIVAA
                     PVMALSLSFDHRIIDGATAQNFMNYIKQLLANPELLVMEV"
     gene            complement(37502..>38469)
                     /locus_tag="C1I60_RS19995"
                     /old_locus_tag="C1I60_20040"
     assembly_gap    38470..38479
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="align genus"
     CDS             complement(<38480..38841)
                     /codon_start=3
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345960.1"
                     /locus_tag="C1I60_RS25905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="biotin/lipoyl-containing protein"
                     /protein_id="WP_353505575.1"
                     /transl_table=11
                     /translation="MPVASSEPSVAAQGGAAGTARFEYKFPELGEGLHEGEIIKMHIKP
                     GDKVTDEDIIMEVQNDKAVVEVPCPVNGTVQEVFAKDGDIFNVGQVVAVIAAEGELPEQ
                     EEAPAAAKQEQDAAQGG"
     gene            complement(<38480..>38845)
                     /locus_tag="C1I60_RS25905"
     assembly_gap    38846..38855
                     /estimated_length=10
                     /gap_type="within scaffold"
                     /linkage_evidence="align genus"
     gene            complement(38985..39965)
                     /locus_tag="C1I60_RS20005"
                     /old_locus_tag="C1I60_20050"
     CDS             complement(38985..39965)
                     /EC_number="1.2.4.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371456.1"
                     /locus_tag="C1I60_RS20005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20050"
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="WP_014281492.1"
                     /transl_table=11
                     /translation="MAQMNMKEAIRDALRVELKRDPNVLLFGEDVGHVGGVFRATEGLQ
                     KEFGEERVFDTPLAESAIGGLAVGLGVQGFRPVAEIQFVGFIFEALDQMAIQASRMRYR
                     SGGRYNSPIVFRTPFGGGVKAAELHTDSLEGLLAQTPGIKVVVPSNPYDAKGLMIAAIR
                     DNDPVFFMEHLNLYHAFRAEVPEDDYTVELGKANVVREGSDVTIITYGLMVHTSVKAAD
                     ELEKTKGIKVEIIDLRTVSPIDIDTIVASIQKTNRAIVVQEAQKSSGVAAEVIAQINEK
                     AILHLEAPVLRVAGPDTVYPFAQIEDTWLPTPTRIIDAVNKVLEF"
     gene            complement(40076..41143)
                     /gene="pdhA"
                     /locus_tag="C1I60_RS20010"
                     /old_locus_tag="C1I60_20055"
     CDS             complement(40076..41143)
                     /GO_component="GO:0045254 - pyruvate dehydrogenase complex
                     [Evidence IEA]"
                     /GO_function="GO:0004739 - pyruvate dehydrogenase
                     (acetyl-transferring) activity [Evidence IEA]"
                     /GO_process="GO:0006086 - acetyl-CoA biosynthetic process
                     from pyruvate [Evidence IEA]"
                     /codon_start=1
                     /gene="pdhA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345958.1"
                     /locus_tag="C1I60_RS20010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20055"
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="WP_137063862.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1.2e-06,
                     bitscore: 24.0, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5e-06, bitscore:
                     22.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVPYEVYTEEVEALSVLSPDGEIINKDKLPELTDDQLKEIMYR
                     MVFTRTWDDRAVNLGRQGRLGFYAPVSGQEATMIGSEYALQKEDFIAPGYRDIPQIVWH
                     GLPLYQAFLYSRGHQHGGQVPDGVNVLMPQIIIGAQILHAMGIAMGYKLKKQKQVAITY
                     TGDGGSSEGDFYEGLNYAGVYKLPVIFFVQNNGYAITTPFAKQTAALSIAHKAVAAGIK
                     GVKIDGMDVLAVIKAVQEAAERGRNGEGATLIEAVTYRFRPHSLSDDASKYRSKEEEGE
                     WNAKDPIARFAKYLEKKGLWTEEDTARVKEEAKAKVNEEIKKAEKTEKMTISGLIDSMF
                     ESTPKHLEEQKADFK"
     misc_feature    complement(41251..41265)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.21"
                     /tool="antismash"
     misc_feature    41280..41293
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            41398..42132
                     /locus_tag="C1I60_RS20015"
                     /old_locus_tag="C1I60_20060"
     CDS             41398..42132
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1098: enterobactin/ferric enterobactin esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687407.1"
                     /locus_tag="C1I60_RS20015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20060"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_137063291.1"
                     /transl_table=11
                     /translation="MTDSRYLKRTILKDEINSRFLGETRTLRIYLPPGYNEILSYPVVY
                     CQDGEEFFNFGRIATQANRLILDEGVEPFIIVGVEVNTKIRTQEYAPFGNRFEAYTACF
                     AEEIIPYVEQKYPIRRDSSSRILAGDSLGGSVSLHLALLYPQLFNRIISLSGAYYEASQ
                     EIIARERDLSQLRVWMTVGLQEDAFESDTGIYNFVELNRQCADLLRERNADVSYREKDG
                     KHLWGFWQNELPDALMYFLDRS"
     gene            complement(42291..42755)
                     /locus_tag="C1I60_RS20020"
                     /old_locus_tag="C1I60_20065"
     CDS             complement(42291..42755)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281489.1"
                     /locus_tag="C1I60_RS20020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20065"
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="WP_137063292.1"
                     /transl_table=11
                     /translation="MINVLFVCLGNICRSPMGEAVLRHKAQERGLGAKIRVDSAGTGDW
                     HIGNPPHEGTLKQLKLHGISEQGIQARQMKSRDFEAFDYIVCMDDSNERNMRKLAGGAE
                     ADILKFMDLLPQEKLREVPDPYFTGNFEETYRLMNAGCNALLDKIIEEKL"
     misc_feature    complement(42815..42831)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.71"
                     /tool="antismash"
     gene            42907..43548
                     /locus_tag="C1I60_RS20025"
                     /old_locus_tag="C1I60_20070"
     CDS             42907..43548
                     /EC_number="2.7.6.2"
                     /GO_function="GO:0004788 - thiamine diphosphokinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006772 - thiamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019687409.1"
                     /locus_tag="C1I60_RS20025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20070"
                     /product="thiamine diphosphokinase"
                     /protein_id="WP_137063293.1"
                     /transl_table=11
                     /translation="MIKKRAIVFSGGHLSEKDLQQIQPEDFIIGADKGALFLIEHGITP
                     DVSVGDFDSVTSEEKSRVETASRRMLSCDPVLKDLTDTELALEIAMNEQAEHVLMLGVT
                     GTRMDHTLANIQVLVRAMQHHIGCAIMDAHNYIELTGSTLEIEPMGYTYTSLIPMTAEV
                     TGIELDGFMYPLHNATLKMGQSRGVSNQLVAPKGTISIESGLLLVVQSKD"
     misc_feature    complement(43551..43566)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            43827..44327
                     /locus_tag="C1I60_RS20030"
                     /old_locus_tag="C1I60_20075"
     CDS             43827..44327
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430633.1"
                     /locus_tag="C1I60_RS20030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20075"
                     /product="C40 family peptidase"
                     /protein_id="WP_137063294.1"
                     /transl_table=11
                     /translation="MNMHKIIKKAIITGMAATIGFGTFALEGTNTAQAATATTSVGQKI
                     INYGENYMGTPYKFGASTSTTRNFDCSSFTKHIFQKYGIDLPRTSVAQSNVGHAVSKSN
                     LKKGDLVFFSSGSRATGRNITHVAVYAGGGKILHTYGSPGVTISDLNSGNWKRTYIKAR
                     RVL"
     gene            complement(44398..45093)
                     /locus_tag="C1I60_RS20035"
                     /old_locus_tag="C1I60_20080"
     CDS             complement(44398..45093)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371462.1"
                     /locus_tag="C1I60_RS20035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20080"
                     /product="response regulator transcription factor"
                     /protein_id="WP_137063295.1"
                     /transl_table=11
                     /translation="MNPLILLLDENEESATTYTRQLEQQGYQVVNARNIAGGKSYLEEN
                     PVNLLLLNMDKEQPDGQGLIRTMQQNDPTVPIFVMTSSDDENHIVSCFEQGAHDVIVQP
                     FSLRVFQARVANLLRIFGTARDVKKPIQAGDLHIDSGRRLVSRGGQKLELTPKEFDLLL
                     HLAIHLNQVCSRQQILKDVWKHDYIVDTNVVDVYIRHLRVKVDKGQSFKMIRTQRGIGY
                     SLRTPPEAE"
     misc_feature    complement(45172..45188)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.93"
                     /tool="antismash"
     gene            complement(45237..46295)
                     /locus_tag="C1I60_RS20040"
                     /old_locus_tag="C1I60_20085"
     CDS             complement(45237..46295)
                     /GO_function="GO:0008641 - ubiquitin-like modifier
                     activating enzyme activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430635.1"
                     /locus_tag="C1I60_RS20040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20085"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_137063296.1"
                     /sec_met_domain="ThiF (E-value: 1.7e-58, bitscore: 193.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKATEKTGVQVQPSDRYSRQERFAPFGPEGQRRLASSHVLIIGAG
                     ALGTGIAETLVRGGVGTVTIADRDYVEWSNLQRQQLFQESDAAERCPKAVAAQRRLKEI
                     NSETIIHAHVLDVGVEELEELIQGVDLIMDATDNFDTRLLMNDMAQKHRIPWIYGGCVG
                     SYGVTYTILPGKTPCLHCLLGAVPFGGETCDTAGIIPQAVQMVTANQTTEAFKLLGGYP
                     DDLRGKLLSFDLWQNEYVAIVVDSVKKVDCPSCGTHPTYPYLSGAYRQKTDVLCGRDTV
                     QIRPAEPIRVNLMETADRLASLGEGRVEQNPFLVSFSEGAHRLVIFADGRALIHGTKDV
                     TEARKIYHRYLG"
     gene            complement(46292..47059)
                     /locus_tag="C1I60_RS20045"
                     /old_locus_tag="C1I60_20090"
     CDS             complement(46292..47059)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007430636.1"
                     /locus_tag="C1I60_RS20045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20090"
                     /product="thiazole synthase"
                     /protein_id="WP_137063297.1"
                     /transl_table=11
                     /translation="MLTIGKASFTSRLLLGTGKFPDLDIQSKAMKAAETEILTFAVRRL
                     NLEERDKQHFLDTLDLSRYTLLPNTAGATTADEAVRIAQLARASGLCDMIKVEVIGDSK
                     TLLPDPFETLKASEKLLEEGFIVLPYISDDVILAKRLQKLGVHAVMPGASPIGTGRGLL
                     NPFSLELIIEQAEVPVIVDAGIRSPGDAAMAMQLGADAVLLNTAVSGAQDPVKMAEAMK
                     LAVRAGRYGFEAGMIPVKRYASASSPTEGLVQA"
     gene            complement(47062..47265)
                     /gene="thiS"
                     /locus_tag="C1I60_RS20050"
                     /old_locus_tag="C1I60_20095"
     CDS             complement(47062..47265)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013310519.1"
                     /locus_tag="C1I60_RS20050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_20095"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_137063298.1"
                     /transl_table=11
                     /translation="MKLTINGQNMTFSNQIIHVDQLLKELDLKVKTVVVELNRHILTRE
                     DHDEAVLKDGDSLEIVHFVGGG"
ORIGIN
        1 gcgattaagt tatttgatta tagatcacag attatagttt acataatata tattatgttc
       61 acttaattca tttgcttata cagtctattt atcaatgacg tacagcttca cattctgaaa
      121 accaaagtca ctcacaaaag atgggctgcc tggaatgaaa atatctatcc gtttccccgt
      181 aatggcgcta cccttatcgc gtgctacggc tacaaaagaa tgatccggca aacccgggtg
      241 ggaatagcct gtaaccaaca ctttcgtacc caacggaatt acgtttgggt caaccgcaat
      301 cgtaccaagc ttaagcggat ttccgaaata atccaccgct ccccattttc cattttcact
      361 ggttgcagcg gaatatgctg tagccttcac gtcaactact ttgctgtagt taaatgtttt
      421 gccccatgct tcaacttgtt gaccgtcacc tgccggcgct ttatctgaaa gaagctgagg
      481 ctttgaatcc gaagcagcct ttaccttgtt ctcgaccggc accttaattt gtactcctgc
      541 atatatattg ctggcagcaa gatctgggtt atccttttgc agattatcta cagatacccc
      601 gtaacgttga gcaagtaaaa agaaggtatc accttccttg gcggtgtgaa gcgaagcggc
      661 gtcggctacc ccggctgtct gcgccaatcc tgcaatggct gctgccagca ccgcaaattt
      721 cattgttttt ccaatacgtt taagatgttt caaaagatat gtacctcctc tgttatgcct
      781 gcgaagttag ctgtcggatt cggactcagg agaagcccta tgcttgtgca attcacccct
      841 aggcaccttc catccattcg tatgaagacg gatcagaagt tactgccgtt gttacgtcct
      901 ccgcacttcc catggttttg ggtcccgcat tcagcgtcta aatgtagctg tctgctgccc
      961 cggtaagttt tggctcactg cataatatca caattttgta accttatctg catgaaaatg
     1021 ttgggaacct cgaacatcat actacatctg ttacaatttt gtcatcatga aatcgaaatc
     1081 agttacaaaa atctgaacga ggatgacaaa aaaaagaaaa agccctcccg tcaaacttcc
     1141 accgcggagg gcttgcttca tagcctttac aagctcattt cttacaaaac cttggcaaga
     1201 aaatcccggg tacgatcatg gcttggagtg ccaaaaacct gctccggtgt accttgctcc
     1261 acaatttgac cgttatccat aaagataatg cggtctccta cctcgcgggc aaagcccatt
     1321 tcatgtgtca cgatgaccat cgtcatgcca ccctcagcca gcttcttcat cacgtccagc
     1381 acctccccga ccatttcagg gtccaaagca gaagtcggct cgtcgaagag catcacatgc
     1441 ggctgcatcg ccaaggcgcg tgcaatcgca atccgctgct tctgtccgcc ggaaagctga
     1501 ttgggatagg tgtccttttt gtcttcaagc ccaacggtac gcagcagctc tagtgcaatt
     1561 ttctccgctt cctttgctga ctggcctcta acctgagttg gcgcaagcgt cagattttgc
     1621 agcaccgttt tgtgcgggaa cagattgaaa tgctggaaca ccatccccat tttctcacga
     1681 gtcgcattaa tattatgacc acgggctgta atcggctcgc cttcaaacaa aatctcccca
     1741 tcggtcggct gctccagcag attcatacaa cgtaaaaatg tacttttccc cgaaccactc
     1801 gggccaatga cgacaacaac ctcgcctttt gcaatatcta tatcaatgcc ttttaaaatt
     1861 tcatttttgc cgaacgattt acgcagttgt ttaacggtga tcactggctc tcaacttcct
     1921 ttcccataaa cccaacagct tcgacaagct gaatgtcatt acaaaataaa tagcagccgc
     1981 gatgacgaac ggacttaatc cttcgtaggt gatgttctta atgacttggg cctgatacat
     2041 aatatccacc ataccgatgg tagaaatgat ggaggactct ttaataatcg taataaactc
     2101 attgccgatc gcaggcagta cagacttgaa cgcttgcggt aaaatgacgt gacgcatagc
     2161 tttgcctcgt cccataccga gtgaacgggc cgcttccatc tgaccacggt ccactgcctg
     2221 gatacctgca cggaaaattt cagccagata tgccgagcta ttcagagata acgtaataat
     2281 accggactga agtggcgtaa aattgacgcc cagcgtcaaa gcaactccat aatggatgat
     2341 cataagctgt accagcatag gtgtaccacg aagtacctct acgtaggctg tacccaacca
     2401 ttcaatgata cgtacaccac tcatccgcag cagagagatg atcagaccaa tgataaatcc
     2461 gaacagtacc ccgagcgcag acaacaacaa cgtgtagccg atacccgtag cgtaaaagct
     2521 gcgatatttc caaaatatat ccacgatgtt gttggatgaa acctgtcgat ccgcagagag
     2581 cgcactcgct tccgtggaaa acttttcaat agacccgtct gctttcaggc gagccaacgt
     2641 tttatttaca gatgccagca gttcagcatt tcctttacga atacctacag ctgtttctgc
     2701 tccctcatcc tcaggcaccg ccttggcgag tgttacagtg ccatccaatg tgtatccttt
     2761 agcgacagtg tcttcaatca ctacagcatt cacacgttgg gtccgaagct ggagcaccag
     2821 gtcggagatt ttatccagtg aagttactga ggcattgggc actttctgag caatttcctc
     2881 ttggatactc cctttttgtg ctccgatctt ctcgcctttc aaagcagcca tcgtcgaata
     2941 tttgtcctta tcctccgggc gtaccatgat gacttgcttg gagtggtagt acacatccga
     3001 aaaatcaata ctctttttgc gttcatccgt cggtgtcata cctgacagaa ccaagtctac
     3061 gcggccactt tgcagagcag gcagcaacga gtcaaagctc atgtcctcaa tgaccagctc
     3121 tgcacccaga tccttggcaa tttcattggc gatatcaaca tcaaagccaa caatggtatc
     3181 cttaccgtta attactttat gaaactcata tggcggaaaa tcggcactca tgccgagtac
     3241 aagttttggc tgtgtcttcg cttccgtccc gtatgcagta agcatcggaa gaccagccaa
     3301 cagcaagata accgccgtca aaatcagggc ggtaaaacga tatgcctttt tcaatctttt
     3361 tttctctcct taaattcttt ataataaata agattgtgtc attataaatg aatatgcatg
     3421 attatgcaat gagtgttata ttacaaattc agcatttcta acgtagtacc cacattacag
     3481 cttatacaaa ggagttttta gcatgggttt taaacagacg attcaacata caattgagca
     3541 atatgcccaa cgttttaaga acatctcgtt atatattggc gcaaatccgg agctggggaa
     3601 tgaggagttt ttggcaactg ctcgtctaaa agaggaattg gcttttcacg gatttgaagt
     3661 gcagactcct gttctgggta tagaaacggc ttttattgcg acttatatag ctgcaaaacc
     3721 cggaccagtc atcgcttttc tggcggaata tgacgccctc aaaggcttgg gacacgcatg
     3781 cggacatcat ttgatctgta tgatgagtac aggagcagct gtcggcctca aatcggtcat
     3841 tgacgagatc ggtggagaag tacgggtata cggcacacct gccgaggaaa cacgcggtgc
     3901 caaggttcct atggcggctg ccgggttgtt tgatgattgt gatatagcgc tcatgacgca
     3961 cccttatgac cgttatgaaa aatcgggcaa atcgctggcg attgatgccg tacaattcga
     4021 attctttggg caatccgctc acgcggcggc caatccccac gaaggtatta acgcgctgga
     4081 cgcggttatt caaacgttca acggcatcaa tgcgttccgc cagtaggtga agagtacggt
     4141 acgtattcac ggcattatta atcaaggagg ccaagcagca aacatcattc ctgattatgc
     4201 ctctgcccaa ttttatgtac gggctgctac acgtcatgaa ctgaattcat tgactcgccg
     4261 cgtcattcaa attgccgaag gagcggccct acaagcgggg tgtcgtctga aaacctcgaa
     4321 ttatgagaca tcttatgatg aaatggtgac taaccgtgcg ctctccgatg cctttaccgc
     4381 aaatttggtg ctgacaggca ttccgcagga ggacatcacg gagggcgaag atcacggctc
     4441 catggatatt ggaaatgtgt cgctgcactg tcccgccatt catccgtaca ttcaagttat
     4501 tgacgagaag cacgccttgc atacacctga attccgcgat ttggcgatgc aggatcgggc
     4561 gctggaagga atgttgttag ccgccagaac cttggcctgg accgcatgtg atgtaatcac
     4621 taatcctgag ttgctgacac aaattaagga agaattcgct ctgctgaaaa gcaaaattta
     4681 aaattttaat ttcgccaaat ttttaatttc gtcttctctc cagaaaggag cagcagtcat
     4741 tatgaatcat atgagcagct tttgggtgtt gtttattgtg gtcgatatca ttattttgtg
     4801 gttctttttt cgagcattat atcgaaggaa cagggaaaat cgaaagacac gccgccgtaa
     4861 tgcatttttt cttagctccc cgtctccctc ttcccttgaa caggggcgtc ataaggagat
     4921 tatagaactc atgcagcttc tggaacgatc tattccagcc tcctacgctc atagtgtaag
     4981 gcggcgtgtg atggatgccc atcctcacct gacggatcag gaatatgatt ggcgctggaa
     5041 tgagctaaaa cgatatttta tgctatgtgc aattatgaat cgggtgccca tgttcagtcc
     5101 agatgtggat gaactgtggc acgaaatgct aatgtttacg cgagaatacc agcaattttc
     5161 ggaagccttc tttggccgca tgctgcacca cgcccctcat gccagctcac agccgatgcc
     5221 ggatgaacgg gcatggtttg actggctgta tgtggaatgc tttggctgga accgctatag
     5281 tgcaagccta tgggggactt tttttaatca tccattaccg aataacgagc ttgcacacta
     5341 ttacaagctg acagcttccg ggcagccagc aggcgaccgt tggaatacgc aagaggacat
     5401 gagcatctct cagcaggcac agcaagcggt tcagagaatt gtggaccatc tgcgtaatcg
     5461 ggtgaatgaa gcagtggatg atccagatgg cagactgctg ccgaaggtca actatttgca
     5521 aattgattat ttgctgctgg ccgtcgtatg gtattcttgg tatcagcccc atcaatttgc
     5581 cttgcacatg catcctgatg ctacaggaag tgccgcatta gcaagctcgt caggctgtag
     5641 ttcagcaagt ggctgttcga attgggatac gcacgactcg aaccatcact cttgccacgg
     5701 aagctcccat gatggagact catctcacca cgattcaggt gattccggcg gcagccattc
     5761 ctcgtgcagc agtagctcct catgcggaag cagctgtggt ggaggcgact gatcacagta
     5821 aaaaaggaca ttcctcagcc attattggct tctgcgggat gccctttttc cattgtactt
     5881 tgtcagttct accttgttca ggcactcctg cctggtcgac ttagctcatt cgttccctgt
     5941 cagtgaacga taaatatcca gatacgctcc cgccgacaca tcccagctgt actctcctgc
     6001 aaaagcagtg ctcgtaagct tggaccaatg ctcaggctgg cgataaaaat caaccgcacg
     6061 acgaatcgta tgcagcatat catgcgcatt gtaatttttg aagctaaagc cattcccttc
     6121 gcctgtagac tcgttgtaag catgtacggt atcgttcaga ccgcccgttt cccgcacaat
     6181 cggaatgctt ccatagcgaa gcgccagcag ctggctgatc ccgcaaggct caaacctcga
     6241 cggcataagg tacatatcgc ttgcagcata aattttgcgg gacaaaggct cattgaaacc
     6301 cagctgcgcc gacattttca acggataacg tccagccgct tcccggaacc agtgctcaaa
     6361 ggccggatct cccgtgccca gcacgacaaa ctgaatatca tcatcataca tgatctcatc
     6421 aagcaccctg gttaccaggt tcagtccctt catatccaca agtcgggtta ccatcgcaat
     6481 caaaggcacg tccggtcgta ctggcagccc cagctccttt tgaagaccga ttttgttttc
     6541 ctttttcttc gccaaactgg tgcggtactt cgtataaata cgatggtccg tagcaggatt
     6601 gtagcttttg atatcaattc cgttcacaat acccgacaaa cgcccctgcg ctcccagctt
     6661 acgcaacagc ccttccagcc catatccgta aaattccgtc tggatctcct ctgcgtaggt
     6721 aggacttaca gttgtgacat gatcagagta ggtcagccca cccttcataa agttcagtct
     6781 gccatgatac tccacaccct caggggtaaa atagctacta tccagattca gtagttctgt
     6841 taagacctca tatggaaaat ccccctgata cagcaggtta tgtatcgtaa acaccgtacg
     6901 aatatcaacg taaaagggca aatggcgata attggcattc aatagcaacg gcaccatcgc
     6961 ggtatgccag tcatgacaat gcaaaatatc aggctgaaaa ttcaagtcag gcagtacctc
     7021 caaaatcgcc cggttgaaaa aggaaaaacg ctcgccatca tccatatagc cgtaaattcc
     7081 gtcacgaccg aagtaatatt cattatctat aaaataaacc ttgatcccgt ccaacgtcag
     7141 ttcctctact ccacaatact ggtcacgcca gcccacagag acatgcttga ccgttaccgg
     7201 acgcagagac ttcttatacg tatcgggaat ccccgtatat ttaggcaaga tgatccggac
     7261 atcgcacgca gcctgacgaa gtgccttcgg cagtgcacca atgacatcag ccaacccgcc
     7321 tgttttaata aatggatgtg cttctgctgc cgcaaataaa atgttcatat gtgcttcctc
     7381 cttaatgacc tcaaccctat tttaaaccag ttttgcgtcc attaatctgc ttttctagcc
     7441 cttcgaggcg ctttcttgag tataacgaca ctcagtggcg gaagggtcac ctccaaacta
     7501 tgcagttgcc catggcaagg gatcttggct gtgcgcagca cttcggtgtt cagctggccg
     7561 gttccgccga aatccgaatg atcgctgttc agcagctcga tatagattcc tgccttttcc
     7621 agtccaattc ggtagttctc tcttggcacg ggctgaaagt taataagcac aaccactgta
     7681 tctcccggct ttttcccttt acgtaaatac gtaattacgc tctgtccacg gtcctccgct
     7741 tcaatccatt gatatccatc ccacgaatga tccagctccc acaatgcttt ttcttgtata
     7801 tacaaatgat tgagcgcttt cgtaaaagca tgcagcgaac ggtgactatc ataatccagc
     7861 agaaaccagt caagctgctc ctcatccttc cattcggtaa attggccaaa ttcgcctccc
     7921 ataaataaca gctttttgcc cggtgaggtg atttggtaac cgagaagcgc tcgaagcccg
     7981 gcaaattttt gctcatagct acccggcatt ttatcaagca gcgacttttt gccatgaacg
     8041 acctcatcgt gcgacagcgg cagtgtaaaa ttctcgctgt atgcataggc tatggggaac
     8101 gtcagtaagt tatggcgctc aggcctctga tcgaaatccg tttcaatata atcaagcgta
     8161 tcgttcatcc agcccatatt ccatttgtaa ttaaaaccga gtcctccatc gcttaccggg
     8221 gaggtaacca tcggccaggc actggactcc tctgccatca tcagcgcata cggataatag
     8281 cggaacacgg tttcattcag ttgttgaagg aaggcaatag cctcctcatt ttcaatgcct
     8341 cccttggagt taaaacgata ttgaccgtcc tgcttttcga aatccagccg caacatactt
     8401 gtcacagcgt ctacgcgcag gccgtcaatg tggtacacat ccatccagaa cagcgcattg
     8461 gatatcagaa aagaacgcac ctccggcttg ctgtaatcga acgtcagcgt cccccaacca
     8521 ggcttttctg caatcagcgg gtccgcgtat tcgaatagcg gcgacccatc aaacattctc
     8581 aaaccgtgag catccttggc aaaatgagcc ggaacccaat ccataagcac cccaatgccc
     8641 gcctgatgac aacgatccac caaatacata aagtcctgcg gttccccata acggcttgtc
     8701 agtgcaaaat atccggtgag ctggtatccc caggaaagat catacggatg ctcactgagc
     8761 ggcataagct caatatgcgt gtaacccatt tccgttacat agggcacgag aagctcagcc
     8821 atttccctgt atgtataaaa cgtagcgtct tcttgttgtt tccaggtgcc caaatgcagc
     8881 tcatatatat gaaggggctt tccataaggc tctctccgtt tacgccgcca agccgcgtcg
     8941 ttccaaacat agccctccag tgaagcgacc acggaagccg ttgctggtct taattctgcg
     9001 cgtaccgcat aagggtctgc ttttagaaaa cgttcaccgt ttgcacccgt aatatcatat
     9061 ttgtaaaaag ttccttggga tatacccgga aaaaaacgac tccaaaagcc agattcggga
     9121 actctatata aggaatcctg ttccccattc cagttgttac aatctgtagc aagcccgaca
     9181 tggagagcat gaggagccca caccgtaaaa cggacgccct gttctccgtt ctccacagta
     9241 aggtgggaac ctaaagatcg gtagctgtga taaagcgttc cttcgtgaaa caaataaata
     9301 tcttccggcg atacagcctg ttgcgggaga gtttggtctg tcatcacgtc accaccttta
     9361 tatgtttgtt ggaacaaaat gtatgattcg gaaatacatt tgctttacgg tcaaagctga
     9421 cttaggttat taccccattc tagccacaat gaacagaaaa atgactatga aagaaataaa
     9481 ccttaatttt tgggggatct tacacaccta ttggtttcaa gagtacccca taccgtttat
     9541 gtatgtacta caacagacaa ctaaaccggg agggaaccga aatgtttaat aaagaatgca
     9601 ttgccatgct gctggcaggc ggagagggac gccgccttgc tccccttact tcaacgattg
     9661 caaaacccgc cgtacccttt ggcggtcatt atcgaattat cgattttcct ctcagcaact
     9721 gtgttaattc agacatagac actgtaggtg tgctaacgca atatgaggcg gaatccttgc
     9781 atgagcatat tggagatgga acgccttgga atcttaccaa gacgaacgac aagggagtta
     9841 ccttacttcc atcttataat acagacaacg ctgaatattt gggaacggca gacgccattc
     9901 ataaaaatat cgaatatata gacagtcaaa acccggaaca cgtgcttatt ttatccggtg
     9961 atcatattta ctatatgaat tatcgtgaaa tgctgaacta tcataaggaa aaagttgctg
    10021 cggctacgat ttccgttatg gaagtacctt gggatgaagc gcaccgtttt ggcgtcatga
    10081 gtgccgatga ggagctgcgt gtcaccgaat tcgctgaaaa gccggagaaa cctgaaagta
    10141 atctggcgtc tatggggatt tacctgttta agtgggatta tttgagaaag tatttggtgg
    10201 aggacgccga ggatgagcaa tccagccatg atttcggtaa agacatcatt cctaaaatgc
    10261 tggcggatca agaatccttg tatgtttacg aatttcaagg ctactggaag gatgtaggta
    10321 ccgttaaaag cctgtgggat tcacatatgg atctgttgca aaagaattgc gctattgacc
    10381 tgcaacggac agactggcct atgtatacgc gtgaacgccg cacaaggttg agcgcacata
    10441 agctatctaa ctataaaacg gagcctttgg acagcctcct gcatgattct tgccaagtag
    10501 aaggtcaaat tgaacgttcc gtcgtattta gcggtgtcga ggtaggtaaa ggctcggcta
    10561 ttaaggaaag tatcattatg cctaacaccc gtatcggtcg taatgtgcat attgagcacg
    10621 cgattatcgg tgaaggtgct gtaattcgtg acggtgcagt catcaagggt aacccgagtg
    10681 aaattatggt tatcgggccg aatgaaacga tattcggtaa aatggcggta cgcccacaaa
    10741 cagcccgcat gttgaaagaa gcttatgagc gcaacacacg ccttcgcgct gaaggtttta
    10801 cttcataatg gaaatatgtc aaacagccag cccttcacta taatgaggac tggctgtttt
    10861 cctaatttac atctatttaa aactaacttt cggttccata gccttcagtg agttgcagtg
    10921 gctctatggg ttgctcgtct tgcaaagcag gcaatgaaac tgtaatcgtg gtgcctgctc
    10981 ccaattcact cttgatgagc atttgccctt gatgacgctc cacaaattgc tgcgagattg
    11041 ccaatcccaa gcccgtacca ccattttgat ggtctacctg aaaaaatcgt tctcttactc
    11101 tggcaagatt ttcctcgcta atcccgattc ctgtgtcttg cacagacacc tcgatgttgt
    11161 ccccgatccg ttgcagagac agaaaaataa tagagttctc atgcgaaaac ttgatggcat
    11221 tgtccgcaat gtttaaaaaa acctgcttca gacggttgcc gtctccatga accaggtatg
    11281 ccgtttcctc cgagtccagc tggagtttaa tttgcttcat ttccgctttg gcccatacgt
    11341 tcagcataat ctcctgcaaa agctcgcgca gatcaaccgt tcccatgaca agcttcatag
    11401 catcttgctc cagcttggaa aaatcaagaa tttcctcgac caaaccgatc agtcgatccg
    11461 tctccttgga aataatctgc atcccgatcc tcgtctcctc tggatcatag ccgccagaat
    11521 ttaacgtttc actccatccc ttaatagaag tgagcggtgt acgcagctca tgggaaatgg
    11581 acgagataaa atcatccttg atttgattcg ttctggcaat ttcctgggcc atgtagttta
    11641 gagtcgaagc cagctcaccc aactcaaagc gataatctcc tttaattcgt gcatcaaatc
    11701 gtccttgtgc catctgagct gatacatcac ggatattatt aatcggccta acgatggaat
    11761 tagcgagtcc tgtactgacc acaaatacaa taaccagtac agctaccatg atgcctacgg
    11821 aaaagagcgt aatggtaaat agcttgtcgt tgaccttttc cagcgaggtc gtataccgaa
    11881 caatatacac ctgatctccg acgatattat ccagtttttt ggataccgcc ataacttgct
    11941 gacccgtgcc aggttgcttc ccaatccagc tccccgtatc ccccgctaaa gcttgcgtca
    12001 catcactggt ttgtacactt gtttctgctg caaagttcgt ggaattatct attacattcc
    12061 ccttctcatc aagcaattgc agttccgtat cccctaatga aaacgtatta agcagatacg
    12121 actgcaaaga ctgtcctggc tccttgaatt tgggtgcaaa ctcacttacc gattgaatgc
    12181 gactctccac gtgcttataa atcgtgtcgt aatagtacgc acggattaca atcatgaaaa
    12241 tgacttctac caacagaagc gccaagaaca ccacaaaaaa atagtgaagc acaatctgtc
    12301 tgccaatccc ttttttgatc attgagcctg acctttccat ttatacccat gcccccatac
    12361 tgtttgcaaa aaggcgggtt cggaaggatt gttttcaatt ttttgccgca accgccggat
    12421 gtttacatcc acgattttgg gatcgcccat atattccttg ccccacacat ggtcaagcaa
    12481 aacatcccgg ctgagcggtg tattttcttt ttcaaggaaa aattgaatca gggaaaactc
    12541 tgttggcgtc agctcaatca actgcccgtt tttcttaaat tgcttggcaa tcagatccag
    12601 cgtgaatgga ccagactgga aggatacttt agccgccgtc tcgcgatgca cattcactct
    12661 gcgtagcagc gactgaatac gggcaatgag ctccgtcgga ctgaagggct tgctcacatg
    12721 atcatcagcc cctacagaca aggcatacac cttatcctgc tcctgtacct ttgccgtgag
    12781 gaagatgatg ccaattcgct cattcgtttc ccgaattctt cgacagacct cgaaaccgtc
    12841 cataccgggc accattacgt cgagcaacgc gatatcaata tcccgcaccg tgttcaaaat
    12901 attaagagcc tcatgcccat ccgatgcctc caacacctcg aaaccgtttc gtttcaagtt
    12961 tatgacgata aagctgcgaa tggattcctc gtcttccatg attaaaactt tactcactct
    13021 attctacctg cctttccccc aacttgtttt taatggtttt acgcggttcc agctcactgg
    13081 atcgcttgat accaatcacc tgtgcattgg ttctccatag ctggctatat ccttcattat
    13141 ttcgctccca ttgcgacaat gagaaatatt taatttctgc aatcgttttg tctgtattgt
    13201 ccaaaatgaa ccttaaatag ctgtcctttt ttgatacttt cggatcaatg gtcacttttc
    13261 catgcagctc ctttggtagc ctgaaataga cctgatcatt ggaatcacga tactgctgct
    13321 gcttgaaaat cgttcccttg gccccatccc actgatagaa cgaaacaaaa tacggaacct
    13381 catccagtgg cctgttggac cagcccttgg gcttctccaa attgccaaat tccagaatgc
    13441 catcaccatc tacgtcaccg ctagtaatgg tagcatcctt aaaggtcaca tccatgagat
    13501 caagcttttt gagcttgccg tggtccatca caataacatt ggacaccgta gtcgtctgag
    13561 caatcttggt atctataatg atcccctgcc taccctcggc taccttacca gcaaccacat
    13621 tgtagatact aagcgcctga ctgtccaaat ccagcgatcc gatttcctta aaggttcccc
    13681 cgctgaattg gaatgttttg accgtgaaaa attcattgcg acgcagcagg ataattgtca
    13741 agtcattcaa attgtccccg ttcaggtcca tcttgttatg attaaaatcg tctacgacga
    13801 agtccgtata gcctgtagca tatattttct ctaaagttcc tccggtatag gaatacacga
    13861 tgagcccctt ctgatcgcca ccatcactgc tatccccgct ggaaaagccc gctacaatat
    13921 cgagcgtgcc atcattagtt acatcgacca gcttgaacga ctccagcaca gtaccttccc
    13981 cgtcaaacgt cagcttcttt acccatgttc cgttctgatc ctcgaacaag gccccgtgta
    14041 tttttacact ttcatctggt gtttcgtaaa aaagcactgc ttcgtccgta ccatcattgt
    14101 tcagatcccc cgttcgaatg ggcgtggggt catcggggtc attggggcgc agaggctgta
    14161 ccatgccaag ctgagtaacc actgcaccat tcagctgctg tttctcatca gacatcatcg
    14221 gtgcttgcat cagcgaaatt ggatcgctaa tgacattaca gccgcttaaa aatccaacaa
    14281 gaagcagtga tgcgcagcag ccggttaaca ttctcaacaa catcattttc acttctcttg
    14341 ccgtcccctt cacaatttgt tcttttccac ctgtgtcagt cgtctgccct gaatatcaaa
    14401 tacgagttcg ccgccgttca atccccatat acgggaagca aagcgttcag cgatctccag
    14461 cggcagtacg gtgatcaccg tcacccgttc gtctgagcaa agcttacgga aggtatccat
    14521 cacatgatct gctgaagtcg gatcaagtcc atttacaggc tcatcagcca aaatgacctt
    14581 ggccccgtga acgagcgcac gcgcagtcgc tacccgttgc cgctcaccgc cgctaagctt
    14641 gtcgcatttg tcatgggcct tatccagcaa gcccagatcc tccaatacgt ccattgctcc
    14701 catataatca tcagaacgca ccatcccggt caccattctc cataatggag tctgacccga
    14761 tctgccgatc agcacatttt tgagagcagt ccgattcata tttaaatgcg gattttgctc
    14821 cagatatgcc cattcccgct ttattttcat tttacccgtc catccggatt tcagcacatc
    14881 ctggccatcc accatcagac tgccttcctc ccatggctcc tgcaaagcaa gacagcgcag
    14941 cagtgtggtt tttccacttc cgctcggtcc cactacggct atcagttcac ccgggtgaat
    15001 ttcagcatta atcccgcgaa gtaatggggt ccgttcaggc cccacttgct tggtcagctt
    15061 ctgtattcta atcatctttg tgattcccct ttgtccgcca tcaatactgt ctatagttta
    15121 tagtaaatgt gaaacaaata ccatgcaaac cgcagtttta tgccgtcgat attctttttt
    15181 gaaataacaa tcccaacaag ccgaaaacga cgtagctgcc cccgagtacc agaaacatgc
    15241 tgccttgggt tccatagtcc agtagcgccc cgctaatgtt aggtccaatc acacttccca
    15301 gattaaaatg aaaggatgcc agcacattgg cggcggccaa taatgatttg ggcagcagat
    15361 cggccgcata agccagtccc aaggagaaaa aggagcctac caaaccaccc gccaccgcca
    15421 acaataccag tgttagcata aaatgatttc cgctccacgg catcaacata aagatcaatc
    15481 cacccgctat gcctacgctt ataagcacct ttttacgacc ccaacgatca ctccatatac
    15541 ctagcggcag ttggagcact aatccgccca agctgacaaa ggggagtaat gcggcaatct
    15601 catccgtatg aaagccaata cgaaggccat ataccggaaa gttgctgttc agactggctt
    15661 ccatataacc gtacaaaaat gcaggcaaca gcgcgtacca tgcccagcta tagctgcgcc
    15721 ggaatctgcg tgctgggcgc gcccctgttt ccagcttttc cggtctagaa tccggcagct
    15781 tcatgagcac cagcaacaga atgagcaagc acaacaaagc cagcgctgca aacggaacca
    15841 gcattccata atcaagcaac cacaatccaa gcgggcccag tgcaaacccc agcccgtagg
    15901 acatgccgta aaaagaaatg ttacgcnnnn nnnnnnacta gcagtatcca cagctgggca
    15961 gaataatgca atgcactgtc cccgattccg actagcagtc gcaatacgaa ccacactcgg
    16021 atatctggaa ttagcgggaa cagtagtaac gtaaagagca caagcacaag tcctccggcc
    16081 atcagttttt tgaagcccaa ccatcccaat gtccgttcag ccaccagcgt catagcaaat
    16141 gaaccaatat acaaagcagc ggcattcatt ccgttcagga aagaagaaac acccatctgt
    16201 tccaaagaga tggacaaaat cggcaaaagt agcccttgac acaatccggc cacaacaata
    16261 accgcaatta agataaaata atgcacccgc attgacgacg acatcatggt tcctcctgat
    16321 ataacatgta aaaaatcata atcttaaaat gaatgttaag gaatgatttg catttgattc
    16381 cataatcaat agatatcctt attactatgt atagcgttca tgcaaacaca gccagaatac
    16441 atgcaaattt cagtattttt agtgcataaa agaaaagatg aaaaaaatcg ccatctgaaa
    16501 tgacgatttt acggaaagtc tgtctgatat gtaaccgact ccacatcgtt agggagtctt
    16561 gtatgctcaa tccgaaccca atcacgtcac agcgcactat tttatattat agtggacaat
    16621 gcccagcaga acaagccata ataaataagt gagcaatttc aaaatgctca tgttttgctt
    16681 atggacgggc ttaattacgt tcaccgctct gggctcgaag acagaatagg aggcacttga
    16741 ttccatgagt tatcaaatta aaatagacac ttctccaatt tacgaattac tcggcagctt
    16801 tatggcctat gtaaccaaaa aatgggtaca cgatatggac ttgggccatg agtggatcga
    16861 caaagtggat gcacggctac aaaacgaagt tcgcaccgag ctggctacag cgcaggattg
    16921 cccttttagc gattatgacg cgctttatgt ttgggctttg cttcgaccgg aatcggatga
    16981 aatatctgat tatatcgctt atttggacca cggcccggat gaagatatgt tcgagctgat
    17041 tgttccgcat gttccttttt taacctttga agaatctttg cgcattcgca aggtgtacgc
    17101 ccctctcctc aaattatggg accgggacta cttccgggca atggaaagcg aactgcgtgt
    17161 gctggcagag gaagacgcag cagaaaaacg tatgcttctg aacaaaatgg aaccggaagc
    17221 attggttgaa tacgccacag ccggactgat cgtgcctcat atggaagatt tggatacagt
    17281 tgttctgttt ccagtcgtcc ataatcgtcc gattaattcg tactgttttt atacccgtat
    17341 gctgctgatc cagtatccgg tagacgttcc tgaagaaagc gaagaagaac cgcctacact
    17401 cctgcttcgg ctgactcggg cggtaaatga cccgcaacgt ctgcggattc tgcgttacgt
    17461 ggctcaaggc cctaaatctc tcgaagatat gcgtcatgat ttgagccgat tggaagacac
    17521 gctcatgtct gatatgatga ttttgcgagt agctggcctg ctccgtatcc atattggacg
    17581 ttatcacaag gaaaaattca gcattcgccc cgacggagcg gctgatttac aggtattttt
    17641 ggaatcctat atcggactgt aattggaatt gtgttctccg ttataaccga acatcgttaa
    17701 agcattggct tggaaggagt atcaacatgt cgtatccgaa gcagcacata ttattcgatc
    17761 ttgatgacac cttggtccac tgcaacaagt atttcgatct tattctcaac cactttttcg
    17821 atttgctcca ggaatggttt gcagcccata acctgacgaa aaatacaatt cgtgaaaaac
    17881 aaatcgaaat tgatgtggct ggggttcatc aggtgggctt tgccagcgag cattttccac
    17941 agtccttgat tgatacgtac cactttttct cggagcaatt cggacgccgt acagatcctc
    18001 gggaagagca ggaacttcgc tcgcttggcc gaagtgtgta cgagcaggaa atcgaaccat
    18061 atcccgggat ggtcgaaacg ttaaactcgc tccaaaaagc cggacattcc ctgcatctct
    18121 acaccggcgg tgagcaggtc attcaggaaa agaagattga acagatgaag ctggctaact
    18181 attttgatga tcgcatctac attcgccagc ataaaaatgt cgaggcactg gaggaaatta
    18241 ttcagatgaa ccgctttgac cgaagcatca cctggatgat tggaaactcc ctgcgcaccg
    18301 atgtatctcc tgcccttgcg gcaggcattc atgccgtgta tctcaagcag cccaaggaat
    18361 gggtttacaa tatggttgag ctgcaaaaaa acgttaactc cgtgatgtat acgatacaga
    18421 agctaacaga agtaccccga gtgatacacg aaagcattca attgcatcaa caaaaaagga
    18481 ccctcggcta gagagcacct ctaatatccc cttcaagtag acactcaaaa aagtccacat
    18541 ggtatcatga ggatagagag aacttggagg ggatattttt taattttaaa acttgccaac
    18601 gattttacaa attcaaacag cgcgcgccgg ttaagtattg gcacgcgctc gctgcttagt
    18661 ctttttttat ttatctactt aacagaggga taaccattct ataaatgttc cacggataaa
    18721 atccggtcaa aaagaccaaa aacttcttcc gaatcgtaaa gattctccaa taggctgacc
    18781 tccatcatta aacgtcccga aagcgtagcc gttgtgagca ataacgactg gtttttaatg
    18841 gaaaaataga tactatctac ccattcctcc ataatcggat acgatatgac tcccagattg
    18901 gacaaggtga tggtaaaatt ccacaggggg aatctttcag gcattgtttt cataaccaat
    18961 tcaagacact gttgtttata tttccgatat gaattggaaa atgaagcaaa aaagagcgac
    19021 aacgcatagg gaacccccct tttgaaccat ttgaacgcgg atttcacctg tttttccaaa
    19081 tttccatccc ggaaaaattg cattggaagg cttgcgacgt aatttccgtg catagtttct
    19141 ggcgagtagt tatgcagaaa cttcaaatcc ataggcatgg agacaaacac gcgttgcttg
    19201 tcgggagcat gctgaagtag tccatcagtc attcgataac agatgtattc ggttaatgtc
    19261 atttttaggc tccggcatcg ccgtaaaatc tcaccagtct cctctttgct gaatctatac
    19321 gattttttga cataaccgcc gccttgctcc ggccttctgc cgtaactcaa atcaacggtt
    19381 tcgccagcgc ctgtcccttt ccccctaacc ctggacataa aacctgcaac aaaaaccggc
    19441 atccacataa aagcggaaaa tcttcttttc atacgcagca acctatcttt ggagatgtcg
    19501 ccctttgccg ccttattttt cggatcggaa tctggttcgc ctgagtaata ttccagccat
    19561 ctcttgatcc agaaaaccaa gctcagccca ttagccaccg catggttcat cgcaaatatc
    19621 attgtatatt catttatagg gtagatacga aacggaagtc tggcattggt cggtctgtac
    19681 tgagccagta cctcctcctc cgtaaaatat tgggaaagct tcatcttttc agcctccaga
    19741 aattgttcaa gctcttcctg agaaaatcgc ccccatacaa acgtatcttt ttcgaattgt
    19801 tccacccttt tggcttgcag caaaggattg tccatgatga gcgagcggta gctgacaaac
    19861 aatttttcag cgtcgattct tcttttaaaa gtaaccgttg cgatcatgct attggacaaa
    19921 atataatctt cagttccgaa aaaataggtg ctcgccagtt taatcgcatc catttttctc
    19981 cctcctttcc ttctattctt ttacataaac cctacttttt tgacatgatc catcatcagt
    20041 ttcacttttt gaccgtccag cctggaccac tcaaacccca gcgcctgcaa aataccgtca
    20101 gtcttcttgt tcatcgtcat gaacaacgtt ttgcttgctc cctcaaagaa gacgttggaa
    20161 tgaacaagaa tccgggcaac ctcctgctct gtctctggtt catcgtattt ttcaaacatg
    20221 tattcggtaa aatcctccac tggcattggc tttacattta tatcggcctg cttcaaaagc
    20281 ttggcaaaag ctatcatgct aacctgatgg ctgttaaaca gatgataggt ttcgttgatt
    20341 aaatttttcc ggtcgaacag aagtacaact gccttggcca cctcatccac aaaggagaag
    20401 ttcatggttt tatcttgaat tgcggggacc cggccaagtg tgatcatcga ctttaccaat
    20461 gaataaaatg cattatccga gatattttct tggaagatcc ctgaattgga atcaaacacg
    20521 agattcccga ctctgaacac attggaatca agcccttgtt gccttgcttt aacaatctct
    20581 ttctcggctt cgagctttgt catcacgtaa tagttatcag agctttgctc gacattgcag
    20641 tcatattcag tgaacatgat gctgctctgg tcttctatcc agccgctacc tacgctggtg
    20701 gtggaaacga aattgtaggt ctttttcttc cctgtgccag caaatttgat caatctttcg
    20761 ttcccttcca cattgaccgc ctgaaattcc gagtaatgcc caaaatgctt cacatttgcc
    20821 gccgagttaa tgatcgcatc aatgcttccg gccaaatcct catagcgctc ccgactcagt
    20881 ccaaagcagt cctcggttaa atctccgcag aacacgcaca ccctgtcttt ccagacatta
    20941 tgtccatcaa gctcaaggcc aaaatggaac ttcagcttcg cccacagtct ttccagcgcc
    21001 tcttcgtcat tcgttccccg aacaggtaca tacaccttat attccgtatt ttgcagcagt
    21061 tgaaacaaaa tatggattcc cagataccct gttcctccta ccagcagaac attacggtag
    21121 tcagcccgtt cagaaagatc gatattttca taaccctgat ttttcttccg gtattctttg
    21181 agactctcgc gcattttcca gacaacacca ggtacgccgt tttccccgga agctgccgct
    21241 tcccgtaagg cgtacacgaa ttgttttaat ctgtctttgg aatacttaat gttatccgcc
    21301 aaggcccgaa tcgtcggata ttgaaagatg tcgttaatgc ccacttcaaa atccagcgcc
    21361 agcctcgaaa ccacctgaat cgccttgatc gaattgccgc ccagtctaaa gaaatgctca
    21421 tcaattccga tcgattctat gccgagaatc tcctgccata ccttctggat tttcaaatca
    21481 acgtcatttc ttgggctgct gactgtgtgg tcgcttccct gccattcagg ctcgggtaat
    21541 gccttcctgt ccatttttcc gctcggagtc atcggcatgt catccagctg cataaagctg
    21601 gacggcacca tataatcagg cagctcctgc ataagctgtt cccgcagctc ttctgctccc
    21661 ggttcgccct ctgctgtaaa atacgccgcc agatacttct ccccttgctt atcttccctt
    21721 gcgatcaccg ctacctcccg gacaagcgga tgcttcatta gctgcgcttc gatttccccc
    21781 agctcaatgc ggaagccccg aattttcacc tgatcgtcga ttcttcccaa aaattcgata
    21841 ttcccgtccg gcagccagcg caccagatcg cctgtgcggt acagcttctc tccaccctcg
    21901 taaggattcg ctacaaactt ctccgccgtc agctccggcc ggtgcagata ccccctggcc
    21961 aatccgtctc ccgcaatgca catttccccg gctgctccca gcggcaacag cttttggttt
    22021 ctgtccataa tataaatccg cgtattggca atcggtttac caattggcac cgaggcatat
    22081 cccatatcct cttcccggta cgtccacgcg gttgcaatta cgctcgattc gctcggacca
    22141 taggcgttca tatactccac gctgtccttc caccgcataa ccagctcttt ggtaatcgct
    22201 gatccacccg tcaccagttt tttcagcgtc ggcagcctgt ccggctcaat cccagccaaa
    22261 taagtaggag gcagcagcgc aatcgtaatt tggttttcgt tcatgaagcg tgcaaattca
    22321 ttcagattat taataatatc ccgcgaaacc agatacagcg ttccgcctcc cagcaaaatc
    22381 gtgaacattt cccagaccga ggcatcaaac gagctgctgg caaattgcag catccggtcc
    22441 gatccgtcca ccccccattg ttcctggaag aaatactgga ggttaatgat tccccggtgt
    22501 tctaccatga cccctttggg tttccccgtg gaacccgagg tatagatgat ataagacaaa
    22561 tcctccggct tgttaacagg ctctggattg gcactgccgt ccggttctat atgtcttagg
    22621 ctttcgccat ccaagtccat gattgccccg tgataggtga gcttgtcccg gagatgcttt
    22681 tgcgtcagta caatggacgc actgctgtcc tccagcatgt agtgaatccg ttcctccgga
    22741 taannnnnnn nnncagccga ttcgcctgct cgttcagttc ccggtaggtc agcgtttgct
    22801 ctccccagac caaagccagg tgatctgctc tttgctccgc tcgttcctca aacaacccgt
    22861 ggatcgtttg atcctttgga tattccgcct ccgtatggtt aaaaccgcga actaacgtac
    22921 tcctttcttc ctctggcacg atttcgatat cttcgatcct catctttgga taacggatga
    22981 tttcacagat gatcatttta atctgcccgg ctacccgctc cataaagcct ctgtcatagg
    23041 ccaagctatt gtagcggaat ttaatctgca aatcgttctc aggcacaaca atgaaattaa
    23101 aatcaaaatt tgtctgttcg gagacctttg tggacagaat cctcaaatct gttccgtggt
    23161 cgccctgtcc tttgacagct tcctctatcg gatagttttc aaaggctagc aggttttgca
    23221 ccaatccgcc tccatgggca gtccgcgact gaatttccgc cagcggataa tagtgatgcc
    23281 gctccgatgc ccatgcctcc tgctgcagtt tggcaaccag gtctgaaaag ctttcttcct
    23341 tctctgcccg aactctgaca ggaatcgtat tgataaacag ccctaccatc tgttcaacgc
    23401 cttgaatttc tgccggtctt cccgagacaa ccgttccgaa caccacatcc tgggtattgt
    23461 tataccgttg cagcaggatt ccccatacgg cctgtatcac cgtacttaac gtggcgccgt
    23521 tttctcttgc gattctctcc aaactcgcct tcatttcctt atttatcgta aaatcgtatt
    23581 cctcctgaat gtatcccgga ttagctatac cacttttgat tttaggcagc agcgctggct
    23641 gttcgtactc tgtcagataa ttctcccagt aagcccccgt ctcccggtca ttcctttgct
    23701 ccagccactg gatatattga tgataaggat acactgtccc taattgcggt atgcttcctt
    23761 tatgaagcgc actgtaaatt tccagcagct ctttaaatac aatgccaaga caccatccat
    23821 ccataatgat atgatgaaaa ctcaaaatga aacgatagct gtgggcattc attctaacca
    23881 aggcaaatct gatcagtggc tcccgggtga ggtcaaaacc cttttctcta tccttgtcca
    23941 aataggcttg gagatggttt tctttctctt cctctgttaa gaaggaaata aactcgaaaa
    24001 acatttcagc cggcctatcc tttaaaacga cctgaaccgg tttttccacc ttttcataaa
    24061 caaaggcggt ccgcaaaata tcgtgtcttt gaatcatctg ctggaaagca cgctcaaaca
    24121 agctcctatc gatttcaccc tccagactga tcacggcttg ttcaaaatac gcgtgcgagt
    24181 tttgctccct taggaagtga tagagcattc ccgactgcat aggggtcaat gtataaatgt
    24241 ctgtgatatt gggcttagag tcccccatcg cgcggtatac ctcttctacc tccgccgtcg
    24301 taatgttgct ggaacttaca tcactggctg tcagttccgt atattcctgt gatgcgcaat
    24361 gctcgataat ttgctccaga tttcgcttaa agccttccgc cactgtgatc agcgtggcct
    24421 tttcatattc gtgcttgtga taggtgaaac tcaaccgtag ttttccatca gtcacccttc
    24481 cgttaatgtc caagcagtaa ggtctttgca tgtcgggtga aaccgtctca tcggtaagaa
    24541 catcggagat ggtaaatatg tcggtatcga tatcctggtc aaactgcccc aggtagttaa
    24601 agctgatctc agggtgcaaa ttaaacctta agatttcctc gtcccgaggg aacgtctggt
    24661 attttaaaat gccgtagccg atgccttttt gcggaatgcg ccgtaggctt tctttgacgg
    24721 ctttaagccg ggaagacacg ttcttgacgc cttccatatc caaaatcaca gggtactggg
    24781 cggtaaacca gcctacggtt ctgctgatat ccatatcctg aatgatttct tcgcgtccgt
    24841 gtccttccag gttaacaagc accttatctt ctcctgtcca ttcccgaata gcctctccca
    24901 atgccgtcaa aagaacatcg ttgatttcag tattgtaagc cttattcact tctctaagca
    24961 gcttggcggt ttggaattca tccagcacga tttcgatatg atcgctatcc atatatgttc
    25021 tgccatgaac ggaatgatcc ttgggaattg gcttgatttc attctgctcc agctcggacc
    25081 agtacgtgat ttcttgcaga agctccccgc tgctggcata cgtataaagt tgttcagacc
    25141 atgccaggaa agagtccgtt ttccctctga atgtgacttc ttccccctgc tccgcctgtc
    25201 ggtatcctgt agaaatatcc tcaaaaagaa tccgccaaga aatcccgtca accaccaggt
    25261 ggtgaatact tacgcacaga tagtcaccgt ctttcgtttt gaacaagccc gcttgcatca
    25321 gaggtccaca ctctaaatcc atgcgggact gaagctgggc ggcttcttcc tttacggagc
    25381 tatcatatat atcatcattt gtaagatcct ttacctccag cgagtatagc tcaccttccg
    25441 tgcctcggtt gaacagaacc acctgtcccg ccttctcacg cattacaata cgcaaagcat
    25501 catggtgttc caccaaacga tcgaacactt ttcttaacat cctttcgtca aacccctgtt
    25561 tcctatgtaa cagaacggac tggttgaagt gatgttttgc tgcaaaaggc tgctcaaaaa
    25621 accagctttg gatgggcgtg agcatgattt cccctgttac cattccttga aaagcagtat
    25681 gttcgacaga ttgtacatag gcactcaatt gttcaatcac aggatggtca aaaagttcct
    25741 tcagttgcag ctttagctta taatcgtgaa gcttggacac gatctggatg gctttaatag
    25801 aatctccccc cagattcaga aagtgatcct taatgcctac ccgttcgact ttcaggactt
    25861 ttccccatat ttcagccaat atttcctcta ttttgtctct cggtgccaca tattcctccg
    25921 ttgcattcac gctcagatcg ggctcgggca atgctnnnnn nnnnnttcgg atctatcggc
    25981 aggtaggctc cgcccgcttt gagtgttccc aggatgccta tgaccatttc catggaacgc
    26041 tccgccatga tggcgacgat atcatccggc ttcactccat gctctctcaa gactgtggcc
    26101 agccgattcg cctgctcgtt cagttcccgg taggtcagcg tttgctctcc ccagaccaaa
    26161 gccggatgat ctgctctttg ctccgctcgt tcctcaaaca gtccctgaat cgtgtgatcc
    26221 tttggatatt ccgcctccgt atggttaaaa ccgcgaacta acgtactcct ttcttcctct
    26281 ggcacgattt cgatttgcga aataagagtt tcactttgct ccatgacttg agcaaataaa
    26341 tattcaaagt gggaaataac gttctcaata gggatgaatc tttcaaaggc ctgtatctga
    26401 tagtcaaaat taacggctac atccgcttca ccttcttgtc cccatatcag gagattgagt
    26461 gcatttcttt catgatgatg cggcatactt acaatccggc ttgctgcgcc gatcaatgct
    26521 tctctcgttt cctgttcttc gaaagaaagc gatatatcaa acagtttgcc tttctcattg
    26581 ctgttctcgt aaaccgcccg gtaaatttca ccgaaagaca ttttctgatg acgatagcat
    26641 tgcataagct cacgtttgat gctcttaatc agttctttga agcttatatc tttctcgggg
    26701 ctgatccgca gcggcagcac gttggcgaaa tgtcccatag tctgcttata tttcgctttg
    26761 ctccgattaa aaaccgggac gccgatcacc atttcgttcc gattgcaaat cttgctgaaa
    26821 tacaggaaca gtatgcctaa aaaatagtgg aacgacgagc atccttcctc tttgcaaaat
    26881 tcaatcattt gattgtataa cgccttgttt atagttaagg ttcgccgatc actccaaacg
    26941 gaatcgccgt caccatcatc gacatccata cctctgctca acagaggctc gggaatggtc
    27001 aggtatttgt tctgccagaa cgccctgtct tttaaaaagg ccggagaatt cagataattc
    27061 tgattatcgg aaataaaatc agcataggaa tagaccgttc tgttcatttc gccaattcct
    27121 tgcaccaatt tattgtaatt gtcaaacatt tgactgatta agagagcaaa tccccacccg
    27181 tcgatcacca aatgatgaac tttaagtaaa atgaagtatg tgttcggggc acctttcaac
    27241 aaaacaaatt gaaaatagaa gtcctctggt tgaaaaggtt ttaaaaactc atttttcatc
    27301 cagttgatgc aaaaagagtt tggattttcc tttaccgaaa aatcatgaaa cgcaacttca
    27361 tagtcagctt ccggcaaaaa tgttaaataa ggctctccct ttttatcaat aaaacgggta
    27421 ctcagagaat cattctgtgt gattaataac tgcatggact gcctaatgat agctgtattc
    27481 aggtttcctt taacctcaac atacccaccg atattgtaaa taggctttcc agggtacatg
    27541 cactgttcga accatatatc tttctgatag gaacttaacg gatactcctt gaaacttatt
    27601 acgctcgttt gcataaaatc ccctccgttt gttaatcatt tcatgcgttc tactccatat
    27661 tccaaaaaat catttccact acaaataaaa gaagcctgtt cccatagaaa aaacacagga
    27721 acagacagca gacttcgccc ggtttccttc ggcaacctgg caatcatggc tgtttaatcc
    27781 agctttagac ccatggcttt gtgtccacca ctttcgaggt gtttacgatt aacgggaatt
    27841 actttcgtat atttttttac atcttttgag tatgctctta tgcttcttcc tcctacattc
    27901 ggtaggagct gaccttgggt tctcaaaaca tttatcttga catagtttca caatacgttg
    27961 ttagctgccg attaaaatac ttcagcaagc cactaaattt ctgtcatccg acaactccag
    28021 ttcattttac ttagtgagtg tagttggaat gattaagaac aagtaagctt actgtggagg
    28081 atatatccag ggtctagtca caaagcgtag caccccaaag aaaagaatgt ccttgtcctt
    28141 gcaagaaatg tcgcgcctgt gaacaaagca ttaatgtcaa ccaagcgtca aggagcgcac
    28201 atgggcaata tcgccctggt catagaaatg ttagacagcg tacaggcgaa gttcattttc
    28261 caacgaaata ttccagtgtt tttgccacgg ttacttcgat ctcagcacct ggttggaaac
    28321 atggctgacc atctcaattt caccggctgt caaggtaaac tgcatcgcct tcacattttc
    28381 ctcagcatga tgtacttttg aagccccagg tatcgcaaat acgttctctc cgtgagcgtt
    28441 aatcagccaa ttcagagcaa tctgcgttgg cgacacgtta tattgttgag ccagctgttc
    28501 caatgtttca atcagcggct tcgatctccg cagccccgaa tcccggaatg ccgccgtcca
    28561 cttgcgcgga cccttgatcg acttgactag agaaggattt ttatggaatt tcccacttaa
    28621 gatcccctgc attaacggag agtatgcgat gatcgccaca ccaagctctt tagccgtgtc
    28681 cagaattccg ttctgttcga ttctccggtc gagcaggctg tatttcactt gattcgaaac
    28741 taggcgaagg ccgtgctcac gcagcacacg atcggcttca cgtatttgtt gcgcggaaaa
    28801 gttgcttacg cccacatatt taatctttcc ctgcccaacc agtttagcca tcgcattcat
    28861 cacggcgcca accgaagcaa aagagtaagg cgaatgcacc tgatagaggt gaatcgtccg
    28921 ttgatccaaa tggcgaatac gttcatcaat cgttgcagtg atactacctg cggtccgaaa
    28981 ggccggccac cacttcgtag cgatattcgc ctgttccgcg agcggtcctc cgatctcatt
    29041 cagcgtgccg gccagtagct gttcagactg tccgccaccg tatgcttcag cggtatcaaa
    29101 ccaattaatt ccaccttcta aactggtctg tacgatttgc cgtatatcct cccgccgcag
    29161 cactggccag aatttcccta ctatcccttt tccattgctg aattgccaac acccaagccc
    29221 cagcggtgac agctttaaat ccgagttgcc cagcttacgt aattgcagtg agcctgccac
    29281 atttgccgtt ttcacttcca cgatccttcc atcatctccc gtaaaaaaat tttcatgtga
    29341 aacgattgcg ttcacgtttt aaagcacaaa cataactttt cttcctggtt tgcacagtcc
    29401 gccatgggaa gttttttgaa cgctatgcat aaagtctgct ttataaacta ctttaaaaaa
    29461 atacttttgc ataaccctta tttgttttat cggttggaag cttacaaatg tttaataaaa
    29521 tgttatacaa gcatctctta tggggaattt tggggtgcga aacataaaaa agatgactcc
    29581 tgatgaactc agaaatcatc tgatgatagc tagaaaaggc cttctttttc aatctgccga
    29641 aaatcatacc ctgtgcaagt atcagttttc ctcacgaacg ctaagttgcc ctgtacctgg
    29701 ttcattcaga acaattcttg ctttgacggt cgatccatct ttgcgcttaa aagatagcag
    29761 ctgtgtctgc cccttcgtca acagagattt gagcatcgtt tccgtaatct gcttaccagc
    29821 gtattccttc cagacgacaa agccgcagcc ctgtttgtag tggctgcatc catatccttt
    29881 gcggccttca ataatgctcc cgccgcaatt cgaccgcggg cagctgccta aagtctgcct
    29941 ttggcccggc gaagtgccca acggctcggc ggacgaagct cgcgctgccc tcgtgcttga
    30001 gctactcccg actgaacccg atgcagtacg ccctcctgca ctcgatagta cttgctccgg
    30061 tgacgatgct tcgcccgagt tgttggtacg tcgtgacgga gcgcgtgcag ccccttgggt
    30121 ggtgatgctt ccgcttccac ttgctcctcc actacgggtg gctcccttac tacccgagcg
    30181 tttgcccctc gcttcctcac caaaagcgtt tgctggagcc ggtggttgct gcctcacctt
    30241 gtcaatgatg gataacgtaa actttttaac gttatccata aacttttcct gggcagcttc
    30301 tcccttggaa atttgatgca gacggcgttc ccattgtcct gtcatctccg gcgaagctag
    30361 caggtcgacc cccgcgttgc ggatcaggtc aattgccatt ttccccttat ccgtaacgag
    30421 aatctttttg cctttcattt caatgtagcc taccttcttc aaccgttcaa tcgtagcagc
    30481 acgtgtcgca ggcgtaccta atccagcatc cttcatgacc tcacgtaatt cctcgttctc
    30541 catctgcttg cctgcactct ccattgcttt tagcaacgtg ccctctgtgt agcttttagg
    30601 cggctgtgtc gccttctctt tcatctcggc gcgaatacaa tccaccggac ggcctgcatc
    30661 aatctcaaac tttttgtccg tccattcgtc tgtttcctct tcttcctctt tcttcggtgc
    30721 tttgctcttt ttgcctttat cctgatcagc cttgctcaga actactttcc agcccaagga
    30781 cagaagctcc ttaatgcttg ttttgaacag atgcttgtcc acttgggtca tcacggtatg
    30841 cattttatat tcggcaggcg ggaagaaatg tgacaaaaac ctgcggatga tcaggtcata
    30901 tacattttgt tcctccttgc tgagcgttcc cggtcttttc agtgttggca atatagcatg
    30961 gtgatcctca acacgggctg gattgcagac agctttattc tgtttatgga ccaaattggg
    31021 gttcgcttgc tgtaccagat cagcataagg acctgtgccc agcatacgaa gcgccttatg
    31081 catgccgtct atattttgct ccgttacata gttggaattg gtacgcggat aggaaatgac
    31141 cttatgccgc tcatagagcg cttgtgcaac atccagcgtt tttttagctg aataactata
    31201 cttggcattc gcctcacgtt gaagcagtgt caaatcgtac agcttgaaag gatattcctt
    31261 cgtctgcttc gtatcatatt ttgtgatttc acctgttttt ccgcgaactg ccgctgctat
    31321 cgcctcagct tcttctggct tggtcagccg atctccttgc cacgcacctt tatacttggt
    31381 ctgatcttgc ttaaactctg cccacacgtc ataaaaggtt tgagactgaa acgcctcaat
    31441 ttccttttca cggtcatgga tcaatgccag tacaggagtc tgcacccgtc cgaccgacaa
    31501 taacgcgtta tgccgtgttg taaaggctct ggaagcattc ataccgatca accagtctgc
    31561 ctcacttcgt gcccgcgcag cctgagttag aaattcaaac tccgatgcat ctcgcaagcg
    31621 ttcaaagcct gccgcaatac tctccgccgt taaatctgag atccatagtc gcttgaccgg
    31681 ctgacgcagc tttaactgct gttgaatcaa ggcaaaaata tattgcccct ctcgccccgc
    31741 atcacaagca ttcacgattg cattacagcg tttggccagc tcaccaatta ttttcagctg
    31801 atcttttgtt ttcggattcg gtacaatttt aaactgctcg gggataatag gaagatcttt
    31861 aatattccag cgtttgtact tggcatcgta tgcatccggc tcagcgagac ctagcaaatg
    31921 accgatcgcc caagttacaa tatatttctc cccctccaga taggtacggt tatttttggc
    31981 ccttggctcc ataacagccg caatagtgcg tcccatatcc ggtttttcag caataattaa
    32041 cgtcttcatt catattccat tccttcctga cggccttctg cttcccttcc ctggctcaca
    32101 cgtaataaac gaaaggtaaa tgaaatacag gcagggcctc atgcaaaagg agccttctcc
    32161 cggcgaaagc tcctttgtcc attcacttgg tctagcgctc caacaatata cgtgtattat
    32221 accatagata ccatcattct ctcaggtgat gatttacgaa accttgtaac gataatagtt
    32281 actgtcatta tctataaggt ctatgtaaaa gagctataaa gaaagatgat ttaaatgaat
    32341 tttcatctaa aatcactccc cacataacca tacgagttat atttatgtaa ttatatataa
    32401 catataaaac aaatttttga tcattttcat aaaataattt cattattcaa taaaaaagct
    32461 acacttcact cctgttttta tgttatgatc gctgtataaa acagacttgg agatttgaga
    32521 ttttaataaa gtcatattat atgacattaa atttacatcg ctttacatac aatgataaca
    32581 aataatgttt tagaaaaatc tcgtaattca atggttatct ctccgcattt tacaaacctg
    32641 agcacgctag tcctttaaac gcaacaaagc cccatccgag gatggagctt tgactggaca
    32701 actaatatat aacttatatt tacaccaaaa cggtagcgcc catcaggtat ttatcgacct
    32761 cacgtgcagc ttcccgacct tcattaatgg cccacacaac aaggctttgc ccgcggcgca
    32821 tatcaccagc agcaaaaacc ttatctacat tcgtaacata tttcccgtaa cgtgctttaa
    32881 cgttagaacg acgatcagtt tccaaaccaa tttgctccac aattgtttgc tcaggaccgt
    32941 cgaatccaat cgcaatgaga gcaatctgtg ccgggaatac gcgctccgta cccggaacag
    33001 gctgatagat cttgcgacct gtctcatcca caatacgctg aatttgaatc gtgtgcagct
    33061 ctttcaaatt accgttctca tcacctacaa acttggtggt catgatggag aactcacgcg
    33121 gatcttcccc aaatatcgcc ttcgcttcct gctgtgcata atcaagagtg tacacgttcg
    33181 gaaattgtgg ccaaggattg gcaatagggt cacgttccac aggagctttg gcatgtgtac
    33241 caaattgtgt aacacttcga caaccatgac gcaacgaagt agccacacag tccgaacctg
    33301 tatcaccacc accgattaca ataacatcct taccttggga ggacaaataa ttgccatctt
    33361 ccagattgga atccaggtag ctcttgatgg taccgttcaa ataatccatc gcataatgaa
    33421 cgccattcaa atcgctacct tcaatgttga attctctcgg ctttgtggaa ccaccacaca
    33481 gtacaaccgc atcatactca gcaatcagct gatcggtagg aatatccttt ccaatctcgg
    33541 tattcgtaat gaactgaatg ccttccgcct ccagcaaatc cacacgacgc tgaacgacct
    33601 ttttgtccag cttcatggaa ggaatgccgt acatcagcag cccgccaata cgatccgcgc
    33661 gctcgtacac agttacgctg tgtcctgctt tgttaagctg cgcagcagca gccagtcctg
    33721 cgggaccaga gccgacaata gctacccgtt tgcctgtacg cttttcaggc ggattaggga
    33781 caacccagcc ttcctcaaag cctttttcga taatagcttc ctcaatcgtc ttgatcgtaa
    33841 cagattgccc gatcaggccg accgtacagg aaccttcaca tggcgcagga cagacacgcc
    33901 cagtaaattc cgggaagtta ttcgtcttgt gcaaccgatc cagcgcttcc ttccacaaac
    33961 cacgatatac gagattgttc cattccggaa tcagattatg aactgggcag cccaaagtcg
    34021 ctcccatgat gtccatcccc gtatgacaat aaggagttcc gcagtccata caacgtgccc
    34081 cttgggtacg cagctcttct tcggacatat gcttatggaa ttcttcccaa tccttaatac
    34141 gctctgccgg atcccggtct gtaggaagct gtcgtgtgta ttccataaat ccagttggtg
    34201 tagacatgtt acgttccccc atctcttcgc ttatgaaccc cgttcaccca tccgaactca
    34261 agtcaaattc gaatttgtct gtttgtatca tgaaagggtc tattctcgtt gaatttgatt
    34321 tattgtatca caatacagcg caaaagtaat gaaaacttat gcaactttct gcatcaacag
    34381 ccaaaaggat tttttatatg gttcattaat ttttcaaatg agcgaggtca gatgtacccc
    34441 aatcttactt cgtcctctcg taaacgacaa aacggtagtc gtacgggttt ctttcatcct
    34501 tgacaccggg agtctcactg actacattcc agccattcca atccagctca ggaaaagtcg
    34561 tatctccctc gaaaatctca tcaatcctgg ttacaattaa ccgatcagca tgtgtccaga
    34621 acagtgaata aatctccgcg ccgccgatga tcatcagttc ttcctgcgcc gccaattgga
    34681 gaccttcttc cagagaatgg atcacttctg cgccctccgc cagatagctc tgatcacggg
    34741 tcaaaataac gttacgccgc ttgggcaggc tttttccgcc aaaggattcc catgtcttgc
    34801 gccccatgag tacggtttta ccaatcgtct gctccttaaa gaacgccata tctctcggca
    34861 ggcgccaagg aaggctgtta tcccggccaa tgacgccgtt ttgtgccatc gcccagatca
    34921 tcgaaatgct cataactcac agctccccca aatcagatag cgactggcgc cttgataccc
    34981 ggatgatatt cgtagttctc aaaagtaaag tcctcgtacg tataatcaaa tatcgaatcc
    35041 ggtttacgca ggattttgat ctgaggcaat ggataaggat cacgctccaa ctgcgtatgc
    35101 acttgttgca tatgatttga ataaatatgt acatcgccac cggaccaaat gaattcgccc
    35161 ggctccaaac cacactgctg tgcaaccata tgcgtaagca atgcataact ggcgatatta
    35221 aaaggaagac caaggaaggt atcgactgaa cgcatggtca gcatacagga aagcttccct
    35281 ccggccacat aaaactggaa tacaaaatgg catggcggga gcttcattga atcgatttca
    35341 gccacattcc aagcactgac gatatgtcgg cgggaatccg ggttgttttt aatcgcttca
    35401 atgacattcg caatctgatc gatatgttgt ccgtctgttg tttcccacgc acgccattgt
    35461 gagccataca caggtcccag attcccctgc tcgtctgccc attcgtccca tatcgtaacc
    35521 ccgttctctt tgagataaga gatgttagta tctccccgta aaaaccacaa taactcatgg
    35581 atgacggatt ttaaatgtac tcttttcgtt gtcaccaagg gaaaaccctt ggacagatca
    35641 aaacggagct gtcttccgaa aacagaaagt gttcccgtcc ctgtacggtc ctcttttttc
    35701 actccattct ccaatatatc ctccagcagt tccaagtaat tgcgcacttt atttctctcc
    35761 tttaagcata aataaacacc ggcattcata aaatccggac gtaactgaac gttaaaacca
    35821 tttcacgttc acgaacagca tccgatattc caaagccagc agcgtcaaat tctaatctag
    35881 aaaagagctg ctattctgca cccatatcta tatttagttt atcatggact acacattatt
    35941 gactatctac tgtgtgaatt ttcatcgtcg tcctgaaaat cctaaaatat gaaaaaaaga
    36001 gacaaagaac gcagatatag cgctccttgc ctctctttcc atgtatgaaa atcaaaaacg
    36061 agataatgaa ttgggattag cgacgtggtg ccaatgcatg gatcggatga cccagcacga
    36121 cttccgctgc ttccataacg atttcgccca atgtagggtg agcatgaata gtcaaggaga
    36181 tatcttcgag tgtagcaccc atttcaattg ccagacccag ctcagcaata aggttggaag
    36241 cttccagacc tacgatttgc gtacccagta ccagacctgt gtcagcgtca gctacgattt
    36301 taacaaagcc ttcagtagcg ttcagggaaa cggcacggcc gtttgctcca taagagaact
    36361 tgccgacttt gacattgtgg cctttttctt tagcttgtgt ctcagtgtag cctacgctgg
    36421 agcattctgg atctgtgaaa acaacagccg gaatacattt gtagtctact acagacggtt
    36481 ctcctgcgat cgcttcagca gccactttac cttcgtaaga agctttgtga gccagagcaa
    36541 gaccagcaac gatatcgccg attgcaaaga tatgaggaat actagtgcgt ccttggtggt
    36601 caactttcac cattccacgc tcatccagtt ctacaccgat cagatccaga cccagttcac
    36661 cgtctgtgtt tggacgacgt ccaacggtca caagcaggta atcagcagtt acttctttgc
    36721 tttcgccgtt aacggagaat ttcaccgtta cgtctttatc tgtttgctct gcactttccg
    36781 ctttagcacc agtgaagatt tcaataccag ttttcttcat gctcttcgct acgatcgaag
    36841 tcatatcctt gtcgaagcca ggaagaacgg tatccatacc ttcaatgatt gttactttgg
    36901 aaccgaattt ggagtacatt tgtccaagct ctgcaccaat gtatccaccg ccaattacga
    36961 tcaggctttt cggaatttca ggcaggttca acgcttctgt agaagacaga atacgtccgc
    37021 caaacgggaa tggtttcaat tcgattggac gggaaccagt tgcgataatc gcatttttaa
    37081 aacggtagcg tggtgattca tgttcgttga aaacacgcgc ttcgttttcg ttgatgaaca
    37141 tgcactcacc attgaaaact tctactttgt tgcctttgag cagaccgctt acgccgccag
    37201 tcattttctt aacaacactg tttttgaatt cttgtgtttt agcaaagtca acttttacgt
    37261 tctcagcagt aataccaaaa gactcgccgt gttgggcagc ttcatattga tgagctgcag
    37321 agatcaaagc tttggaagga atacatccac ggttcagaca gacaccgccc agctctgatt
    37381 ggtcaacgat taatacgctt tgtcccaatt gtgcagcacg gatagcagct acatagccgc
    37441 caggacccgc accgataacc aatgtgtcaa tatccagaga agcgtctcct actaccattg
    37501 attacacctc cataacaagc aactcaggat tagcgagcag ctgtttgata tagttcatga
    37561 agttttgagc agtagcaccg tcaataatac ggtggtcaaa gctcaaggaa agggccatta
    37621 caggagcggc aacaatttca ccgtttttca cgactgcttt ttcactgata cggccagttc
    37681 ccaagatcgc aacttcaggg aagttgatga ttggagtaaa gaacataccg cctgcggaac
    37741 cgatgttaga gatagaaata gtgcttcctc tcatctcatt ggcagccagt ttaccatcac
    37801 gaccgcgtac agccagatca cgaatggaat cagcaatcat ccagatgctc ttacggtcag
    37861 catctttaat tacaggaacg attagaccgt tgtctgtatc tgtagcaatc ccgatgttgt
    37921 agtatttttt gtagacgatt tcgtttgctt cttcgtcgat cgaggcattc agagccggga
    37981 attgacggga agctgcaacc aatgctttta cgatgaatgg caggtatgtt acttttgtgc
    38041 ctttcttctc agcgattggt ttcatacgag tacggaaagc aaccagctcg gttacgtcca
    38101 cttcgtccat aatcgtaacg tgtggagctg tgtaagccga tttaaccata gcgttggaaa
    38161 tcgctttgcg gataccttta aatggtacgc gctcttcctc agcacgcgga tctgctgctg
    38221 gtgcggatgg cgctgcagct ttcgcttctt ttttagctgg ttcttgcgct tttgaagttt
    38281 ctttcgctgc tggtgcaacc gcttgacctc caccattttt gaaagcttct acatcttctc
    38341 tagtgatttt accatttttg ccggagccac tcacttgtgc gatgtttaca ccttgctcac
    38401 gtgcaaattt gcgtacgcta ggagtagcca gcacgtcttt gtttgttgca gcaggagttg
    38461 cagctggttn nnnnnnnnnc tccgccttgt gcagcatcct gttcttgttt agcggcagcc
    38521 ggtgcttctt cttgttcagg aagctcaccc tctgcagcaa ttactgccac aacttgacct
    38581 acgttaaaga tgtctccgtc tttggcaaat acttcttgaa ccgtaccatt gactggacat
    38641 ggaacttcaa ctacagcctt gtcgttttgt acttccatga tgatatcttc atccgttact
    38701 ttgtcgccgg gcttgatgtg catcttgatg atttcgccct cgtgaagacc ttcgcccagc
    38761 tctgggaatt tatattcaaa tctagctgta cctgcagctc cgccttgtgc agcaacactt
    38821 ggctcagagc tagcaactgg tgcttnnnnn nnnnngttac tttgtcgccg ggcttgatgt
    38881 gcatcttgat gatttcgcct tcgtgaagac cttcacccag ctccgggaat ttatattcaa
    38941 atttagccac gtttaaaacc tcccaaattt acggtgtgct ttaattaaaa ttccagtact
    39001 ttattaaccg catcaatgat acgtgttggc gttggaagcc aagtatcttc aatttgagca
    39061 aaaggataaa cggtatctgg acctgccaca cgcagaactg gtgcttccag atgcagaatt
    39121 gctttttcgt taatttgtgc aatcacttcg gcagctacgc cagagctctt ttgcgcttct
    39181 tgaacaacga tggcacgatt tgttttttga atggaagcca cgattgtatc gatgtcaatt
    39241 gggctaacgg tacgcagatc aataatttcg actttaatac cttttgtttt ttccagttca
    39301 tcagcagctt tgacagaggt gtgtaccatc aaaccataag tgatgattgt aacatcggaa
    39361 ccttcacgaa ctacgttcgc tttacccagc tcaacggtgt aatcatcctc aggaacttca
    39421 gcacggaatg catggtacaa gttcaaatgc tccatgaaaa atactggatc gttatcgcga
    39481 atagccgcaa tcatcagacc ttttgcatcg taaggattgg aagggacaac aaccttgata
    39541 cctggtgttt gagccagaag tccttccagg gaatctgtat gcagctcagc agctttaacc
    39601 ccgccaccaa aaggcgtacg gaatacgatt ggagaattgt aacgtccacc ggaacggtag
    39661 cgcatacggg atgcttgaat cgccatttgg tcgagtgctt caaagataaa gcctacgaac
    39721 tggatttcag ctacaggacg gaatccttga acacccagac ccacagcaag acccccgatt
    39781 gcggattccg ccaacggagt atcaaacaca cgttcttcgc caaactcttt ttgcagacct
    39841 tctgttgcgc ggaatacacc gcctacatga cctacgtctt caccgaaaag caagacgtta
    39901 gggtcgcgtt tcaactctac gcgcagtgcg tcacgaatcg cttctttcat gttcatttgt
    39961 gccatttgct tcatttcctc cttaaacatt gacagatcag tttcagttca ggtccaattg
    40021 aaaaacagac cggatcgggt tgccgcccgg tctctctgat ttatttcaag ctcaattatt
    40081 taaaatcagc cttttgttct tccagatgct taggcgtaga ttcgaacatg ctgtcgatca
    40141 agccggaaat ggtcattttt tctgttttct cggctttttt gatctcttcg ttcactttcg
    40201 ccttagcttc ttcttttacg cgtgctgtat cttcttcagt ccaaagacct tttttctcaa
    40261 gatatttcgc aaaacgggca ataggatctt tggcattcca ttcgccttct tcttctttcg
    40321 aacgatactt acttgcatcg tcagacaggg aatgcgggcg gaaacggtat gttaccgctt
    40381 caatcaatgt agcaccttcg ccgttacgtc cgcgttcagc agcttcttgc acagccttga
    40441 taactgcgag tacgtccatt ccatcgattt taacgccttt gataccagca gcaaccgctt
    40501 tgtgagcgat cgaaagagca gccgtttgct tcgcaaaggg agttgtgatt gcgtaaccat
    40561 tgttttgtac aaagaaaata actggcagct tgtatacacc agcatagttc aggccttcgt
    40621 agaagtcacc ctcagaagat ccgccgtcac ctgtatatgt aatggcgact tgtttttgtt
    40681 ttttcagttt gtatcccatt gcaataccca tagcgtgcaa aatttgcgcg ccgatgataa
    40741 tttgtggcat caatacatta acaccgtccg gcacttggcc gccgtgttga tgaccacggg
    40801 aatacagaaa tgcttgatat aatggcaggc catgccaaac gatttgcgga atatcgcggt
    40861 agcctggggc aataaagtct tctttttgga gtgcatattc actaccaatc attgttgctt
    40921 cctgtccaga taccggagcg tagaagccga gacgtccttg acgacccaag ttaacggcac
    40981 gatcatccca agtacgtgta aataccatgc gatacataat ttctttcaac tgatcatctg
    41041 taagttcagg caatttatct ttattgataa tttcaccatc cggagaaagc acggacagag
    41101 cctcaacttc ctctgtgtac acttcataag gaaccttgct cattttcttc acctcaacaa
    41161 aaaaatttga atatcaagtt ccgctgttat aggattatta tacacctgtt atattgcttg
    41221 cgtcaaagat ttagttattt tttttgagtt cgccacattt tgtgtgtgta acagggttta
    41281 ttttttacta taacagctta gtacatgatt gaaattttaa acatctattg caatcagggt
    41341 aatcttaact tattgtgatc tcgaatgcaa aatcatcccc ccgaaaggtg acgaaaaatg
    41401 acggattccc ggtatttgaa acgaaccatc ctaaaagacg aaataaacag ccgctttctt
    41461 ggcgaaacca gaacactccg tatttattta ccgcccggct ataatgaaat tttgagctac
    41521 ccggtcgtgt actgtcagga cggagaggaa tttttcaatt ttggccgtat agcaacacag
    41581 gcaaaccgtc tcattctgga cgaaggcgtt gagcctttca tcatcgtcgg cgtggaagtc
    41641 aacacgaaaa tcagaactca ggagtatgct ccctttggca atcgttttga ggcgtacacc
    41701 gcctgttttg cagaagagat tattccctat gtggaacaga agtatcctat aagaagagat
    41761 tcatcatccc ggattctggc tggagattca ctaggaggca gtgtgtctct gcatttggcc
    41821 ttgctatatc ctcaactgtt caatcgtatt atcagcctgt ccggtgctta ctatgaagct
    41881 tcacaagaaa ttatcgctcg tgagcgtgat ctgtcccaac tgcgggtgtg gatgacggtt
    41941 ggtcttcaag aagatgcgtt tgagagcgac accggtattt acaattttgt agagcttaac
    42001 cgccaatgcg cagatttgct acgcgaacgg aacgccgatg tttcctatcg agaaaaggat
    42061 ggcaagcatt tatggggctt ttggcaaaat gagctacctg acgcgctaat gtatttttta
    42121 gatcgctcct gagtgaagct tttccaaaac tacagagatt agcggggatt tgagcatttg
    42181 ttgaccagat taggtcgtca tgctctttcc tcttttccct cctcatgttg gatgcgcttt
    42241 caaaaattgc aacgaaaaac ggcatttttt gccgtcttct gtcgttcaca ttatagcttt
    42301 tcttctatga ttttgtccag taaggcattg caacccgcgt tcattaatcg gtatgtttct
    42361 tcaaaatttc cagtaaaata cgggtccggc acctctctca gcttttcttg tggcagcagg
    42421 tccatgaatt ttaaaatgtc agcctctgct ccgcccgcga gtttgcgcat gtttcgctca
    42481 ttggaatcat ccatacacac gatataatca aacgcttcaa aatcacggct tttcatctgt
    42541 cgcgcctgta taccttgttc actaattccg tgcagcttaa gctgctttag cgttccctca
    42601 tgcgggggat ttcctatatg ccagtctcct gttcctgccg agtctaccct gattttcgca
    42661 cctagtcctc gttcctgcgc tttatgtctc agtaccgcct cccccattgg ggaacggcaa
    42721 atattaccca aacacacaaa caaaacgtta atcatttcgc ctctccttcc tattgcacgt
    42781 tacaacttct ttttcctgtt ccattgtagc tatgccctcc aaaattgtgc aagccatatt
    42841 taacgcgtta tacttaaact ctggtagtac atctagaccg catgacagac agaaaggatg
    42901 ttcgatatga ttaagaagcg cgccattgta ttttccggcg gtcatcttag cgaaaaagat
    42961 ctacaacaaa tacaacccga agatttcatt ataggtgcag ataagggtgc acttttcctg
    43021 attgagcatg gcattacacc tgatgtatct gtaggagact ttgattcggt aacctctgag
    43081 gaaaagtcgc gggttgaaac tgcaagtaga cgcatgcttt cgtgtgatcc ggtgctcaag
    43141 gacctgacag atacagagct cgctctggaa attgccatga atgagcaggc agagcatgtg
    43201 cttatgcttg gcgttacggg taccaggatg gatcatacgc tcgctaacat tcaagtattg
    43261 gtacgtgcga tgcagcatca tataggctgt gccattatgg acgcccataa ctatattgaa
    43321 ctcactggat cgacgctgga gattgagccc atgggctata catatacgtc gctcattcct
    43381 atgactgccg aagtaaccgg tatagagctg gatggattta tgtatccatt gcacaatgcc
    43441 acacttaaaa tgggacaatc acgcggagtc agcaaccaac tcgtagctcc aaaagggacg
    43501 atttccattg aaagcgggct tctgcttgtg gttcaaagca aagattgatt gtgacatttt
    43561 tgtaaccttt tcaaaaggat tttttctttt aaaacccttg attatcaagg gttttatcat
    43621 tttctccgat tttaaaattc gatatttttt acaaattgta atttttaatc gttttttaat
    43681 aattggcgtg taagccttgt ccctcaagca tttgagcgta cttttccaac tattaggcgg
    43741 ttttaaagct gttatactca acgctgtaag ttagttagca actcagcaaa atattgcaca
    43801 aatcaatttc tggaggtact tacaacatga acatgcataa aatcataaaa aaggcaatta
    43861 tcacaggaat ggcagccact atcggctttg gaacgtttgc attagaggga acaaatacag
    43921 ctcaagctgc cacagctact acttctgtag gtcaaaaaat aattaactac ggtgaaaact
    43981 atatgggaac tccctacaaa ttcggagctt ccacaagcac tacacgcaat tttgattgct
    44041 cttcctttac gaaacatata tttcagaaat acggcatcga cttgccacgt acctctgttg
    44101 cacaatcgaa tgttggacat gccgtatcca agtccaatct gaaaaagggt gaccttgtct
    44161 tcttttcgag cggtagtcgc gccacgggtc gcaatattac acatgtagcg gtctatgcag
    44221 gtggagggaa aattttacac acatacggta gtccgggcgt tacaatctcc gatttgaatt
    44281 ccggcaactg gaaaagaaca tacatcaaag cacgccgcgt gctgtagcat tcatttgatt
    44341 taacgtattt aagccgggac acagggtctc ggctttttta tattttccaa tactacacta
    44401 ctctgcttcc gggggtgtcc tgagtgaata gcctatacct cgttgcgtgc gaatcatttt
    44461 gaagctttgc cctttgtcta ccttgactct caaatgcctg atatacacgt ccactacgtt
    44521 cgtatctaca atataatcat gcttccaaac atccttcaaa atttgctgcc tgctgcagac
    44581 ctgattaaga tgtatagcca gatgaagcaa aagatcaaat tccttcggag ttaattccag
    44641 cttctgtccg cctctgctaa ccagtcttct tccactatca atatgtaaat cacccgcctg
    44701 tatcggcttt ttcacatcac gtgcagtacc aaaaatccgc aataaattag ccactctagc
    44761 ttgaaacacc ctaagggaaa agggttgaac aatcacatcg tgtgctccct gctcaaaaca
    44821 ggaaacaata tggttctcat cgtcggatga ggtcattacg aatatcggaa cagtgggatc
    44881 attttgctgc atggtacgga tcaagccttg tccatcaggc tgctctttat ccatattcag
    44941 aagcagcaaa ttcacaggat tctcctctaa ataagacttt cctcccgcta tattgcgggc
    45001 gttaaccacc tgatagcctt gctgctccaa ctgacgtgta tacgtagtag cagattcttc
    45061 attctcatcc aagagtaaaa ttaacgggtt cattcttctc acccacctgt gtttggacat
    45121 aggactgcgt aatagataca gacgtatttg atacaaacga ttcaaaccta tttattatat
    45181 tgtaacaaaa aagcagtgaa atcattccac gaaggaagac ttcctgcttt tacggtttag
    45241 cctaaatagc ggtgatagat tttccttgct tctgtgacgt ccttcgttcc atgtattaat
    45301 gctctcccat ctgcaaaaat aactaaacgg tgcgctccct cactgaaaga aaccagaaac
    45361 ggattttgct ccactcttcc ctctcccaaa gaagccagtc tgtctgctgt ctccataaga
    45421 ttcacccgta tcggctctgc tggtctaatt tgaacggtat cccggccgca cagtacatct
    45481 gttttctggc gataggctcc cgacaaatac gggtaggtag gatgagtgcc acaagaagga
    45541 caatccactt ttttgacact gtctactact atagctacat actcattttg ccacagatca
    45601 aacgaaagca gcttccccct aagatcgtcc gggtatccac caagtagctt gaaggcttcc
    45661 gtggtctggt tggccgtgac catctgcacc gcctgcggta taattcccgc ggtatcacag
    45721 gtttctccac cgaacggtac agctccaagc aaacaatgaa gacaaggcgt tttccctggt
    45781 aaaatggtat aggttacacc atagctgcca acacatcccc cataaatcca aggaatgcga
    45841 tgcttttgtg ccatatcgtt cataagtagc cgggtatcaa agttgtcggt ggcatccata
    45901 atgaggtcca ctccctgaat cagctcctcc aattcctcta ccccaacatc cagtacatgt
    45961 gcatgtatga tcgtttccga attgatttcc tttagtcttc gctgagcagc tactgctttg
    46021 ggacacctct ctgcggcgtc actctcctga aaaagctgct ggcgctgcaa gttactccat
    46081 tccacataat cccggtctgc gatggttaca gtgcctacgc ctccgcgaac gagcgtttca
    46141 gcaatcccgg tacccagcgc tccagcacct attatcagta cgtgggatga agccagacga
    46201 cgttgtcctt ccggcccgaa tggggcgaat ctttcctgtc tggaataacg atcacttggt
    46261 tgtacttgca caccagtttt ttcagtcgcc ttcatgcctg aaccaagcct tctgtcgggc
    46321 tgctcgcaga ggcataacgt tttacaggaa tcatgcccgc ctcaaaaccg tatctgcccg
    46381 cgcgaacagc cagcttcatc gcctcagcca tttttacggg gtcctgagct cctgatacag
    46441 ctgtattcaa cagcacggca tctgccccca gttgcatcgc cattgccgca tctccaggtg
    46501 agcgaatgcc cgcatcgacg ataactggaa cctccgcttg ttcaataatt agctccaatg
    46561 agaacgggtt tagcaagccg cgtccggtac caatgggtga agctccaggc ataacggcat
    46621 gtacaccaag cttttgcagc cttttggcaa gaatcacatc atccgatatg taaggcagca
    46681 cgataaaacc ttcctccagc agtttttcgc tggccttgag cgtttcaaaa ggatcaggca
    46741 gcaatgtctt gctatcccca atgacctcca ccttaatcat atcgcacaga cctgaggctc
    46801 tcgccagctg agcgatgcgc actgcctcat ccgctgtcgt cgctcctgcc gtattaggca
    46861 gcaacgtata acgactcaaa tccagcgtat ccagaaaatg ttgcttatcc cgttcctcca
    46921 aatttaatct tcgcacggca aacgtcaata tttcggtctc cgcagctttc atagctttgg
    46981 attgaatatc cagatcaggg aattttcctg tacccaataa cagccttgaa gtaaaagatg
    47041 cttttccaat cgttaacatc attaaccgcc tcccacaaaa tgtacaattt ccaagctatc
    47101 tccatccttc agtaccgctt catcatgatc ttcacgagtc aatatgtgac gattcagctc
    47161 caccactaca gtttttactt tcaaatccag ctctttcagc agttgatcca catgaatgat
    47221 ctgattagaa aaggtcatgt tctgaccgtt aatcgtcagc ttcatttgct cgcctccttt
    47281 atacgttcag gagaaaagct gcttattcca agctcagcca caccagcccc ttttaacagc
    47341 gctgcaatcg cacgcccggt agcttcgctc agcaacacac cgttccggta gtgtccgacc
    47401 gcagtatata ctccttccac gccgggtaca gatccaatac aaggacgccc cgccgctgcc
    47461 tgcggacgca agcccgccca agtgcgtata aaagaagctt cacggacgcg aggcagccag
    47521 gcagaagcac gggccagcag cccctccagg cttccaatag tgacctcttt gtcaaactga
    47581 tgtgacagac tcgtcgcccc aatccaaagc tcgt
//
