LOCUS       NZ_PNXQ01000013        27011 bp    DNA     linear   CON 30-JUN-2024
DEFINITION  Paenibacillus terrae strain PIC167 Contig_013, whole genome shotgun
            sequence.
ACCESSION   NZ_PNXQ01000013
VERSION     NZ_PNXQ01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus terrae
  ORGANISM  Paenibacillus terrae
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 132788)
  AUTHORS   Gomez-Lama,C., Legarda,G., Ruano-Rosa,D., Pizarro-Tobias,P.,
            Valverde-Corredor,A., Niqui,J.L., Trivino,J.C., Roca,A. and
            Mercado-Blanco,J.
  TITLE     Bacillales members from the olive rhizosphere are effective
            biological control agents against Verticillium dahliae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 132788)
  AUTHORS   Gomez-Lama,C., Legarda,G., Trivino,J.C. and Mercado-Blanco,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JAN-2018) Proteccion de cultivos, Instituto de
            Agricultura Sostenible, Av. Menendez Pidal sn, Cordoba, Andalucia
            14004, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2017
            Assembly Method                   :: Megahit v. 1.0.3-29-g707d683
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_000235585.1
            Genome Coverage                   :: 130.81x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005217525.1-RS_2024_06_30
            Annotation Date                   :: 06/30/2024 04:15:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,015
            CDSs (total)                      :: 4,939
            Genes (coding)                    :: 4,759
            CDSs (with protein)               :: 4,759
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 180
            CDSs (without protein)            :: 180
            Pseudo Genes (ambiguous residues) :: 0 of 180
            Pseudo Genes (frameshifted)       :: 50 of 180
            Pseudo Genes (incomplete)         :: 143 of 180
            Pseudo Genes (internal stop)      :: 19 of 180
            Pseudo Genes (multiple problems)  :: 28 of 180
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:51:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 58799
            Orig. end                         :: 85810
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PNXQ01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..27011
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="2"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..27011
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27011
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17011]"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17011
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(81..1088)
                     /locus_tag="C1I60_RS14375"
                     /old_locus_tag="C1I60_14405"
     CDS             complement(81..1088)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309448.1"
                     /locus_tag="C1I60_RS14375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14405"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_137062353.1"
                     /sec_met_domain="APH (E-value: 8.3e-22, bitscore: 71.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKSYTKAQIRKITSRFGLIPLKSSLVSSMYRKNAVIQVKTKKGT
                     YALKPFNRTKMIHSNTIQQMEQAASMIRLLKKRKYSYMPAWLPTHSGKLWTLFQGTPFY
                     MSQWIKGRGLENAEDFEKLGWALATLHATSTGLHQIGRGKSPTLQQLRIWKKQDRLFQR
                     KITQISRHDKEYRNWYSTHGKNCKRLARQAWKDLQDTSIVKLLQKENRFPSLIHSDITI
                     PNVMISDDGQLKIIDWDRVKVGSVYADLAKALMNTTQFNPKFVQSLLKGYQKRKPLSRT
                     ERKMVTALYKLPREAWHASLHPTRSRDREILDNWDQSWPLRLQIIRILQEWAHA"
     gene            1405..2091
                     /locus_tag="C1I60_RS14380"
                     /old_locus_tag="C1I60_14410"
     CDS             1405..2091
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280633.1"
                     /locus_tag="C1I60_RS14380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14410"
                     /product="response regulator transcription factor"
                     /protein_id="WP_137062354.1"
                     /transl_table=11
                     /translation="MDKKILIADDEPGIRNALAYALQREGFLVETAVDGEDALEKVRLF
                     HPDVLVLDVMMPKLGGYEVCRRLESRKGIGILLLTAKNDIVDKVLGLELGADDFMSKPF
                     DLRELLARIKALVRRLEREGAPAPEGSETILGPLRVRPSSRTAELEGTVLELTPKEFDV
                     LALLVSHAGRVYTRDELLQQVWGFDYAGGTRTVDIHIQRLRKKLEPYQSLLQTVYGIGY
                     KAEKML"
     gene            complement(2142..2393)
                     /locus_tag="C1I60_RS14385"
                     /old_locus_tag="C1I60_14415"
     CDS             complement(2142..2393)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039236.3"
                     /locus_tag="C1I60_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14415"
                     /product="hypothetical protein"
                     /protein_id="WP_252361722.1"
                     /transl_table=11
                     /translation="MTAIYGLAGRNFSKFVPGMSRIFSRYSSRVLEEDRAVVESQHPRP
                     IPEALRMEAHVPADGPQVRFRNRWYDFLVNDEPRVRLD"
     gene            complement(2910..4355)
                     /locus_tag="C1I60_RS14390"
                     /old_locus_tag="C1I60_14420"
     CDS             complement(2910..4355)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309457.1"
                     /locus_tag="C1I60_RS14390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14420"
                     /product="SpoVR family protein"
                     /protein_id="WP_137062355.1"
                     /transl_table=11
                     /translation="MSSDHRELEYAIAEIMEVASGFGLDYYPMRYEICPADIVYTFGAY
                     GMPTRFSHWSFGKTFHKMKMQYDFGLSKIYELVINSNPCYAFLLEGNSLVQNKLIVAHV
                     LAHCDFFKHNARFSASNRNMVESMSATADRISGYEMEYGSKAVESFIDSVLAIQEHIDP
                     QLIKPQHLDKQRYMELKVREQKEPGKRQRPDGPYDDLWSLDTVKPQPDSTESGGIQIRQ
                     FPPEPEKDVVWFIQEFSEVLEDWQRDIMTMLRDEMLYFWPQMETKIMNEGWASYWHQRI
                     VRELDLTGDETVEFALLNASVVQPSKQSLNPYYLGLKIFEDIEKRWDNPTREEQDRQGR
                     KPGEGRAKMFEVREFDSDTSFIRNYMTKKLTEDLDLYVFEKRGPDWKITDKSWENIRDQ
                     LVFSRVNGGSPYIVVEDGDYLHTGELKLKHQFEGIELDLKYMERTLPYVYQLWGRTVHL
                     ETMIEGKLALFSYDGKKHHRKFV"
     gene            complement(4352..5518)
                     /gene="yhbH"
                     /locus_tag="C1I60_RS14395"
                     /old_locus_tag="C1I60_14425"
     CDS             complement(4352..5518)
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yhbH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370159.1"
                     /locus_tag="C1I60_RS14395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14425"
                     /product="sporulation protein YhbH"
                     /protein_id="WP_137062356.1"
                     /transl_table=11
                     /translation="MPEPRQPYSFVVSREDWSLHRKGYQDQQRHQQKVKDVIKQNLPDL
                     ITEENIIMSDGKQIIKVPIRSLDEYRFIYNYQKQKHVGQGDGDSQVGDVIGRDPASQKP
                     GKGEKAGDQPGHDIMETEVSMEELEDMLFEDMELPHLQQKDKEQIEVESIVFNDIRKKG
                     MQANIDKKRTILENLRRNARQGKPGIHHISPDDLRYKTWEEKTIPQSNAVIIAMMDTSG
                     SMGSFEKYCARSFFFWMTRFLRRQYEKVEIVFLAHHTEAKEVTEEEFFTRGESGGTICS
                     SAYLKALEIIDKRYPPSSYNIYPFHFSDGDNLTSDNERCVKLIEELMKRSNMFGYGEVN
                     QYNRSSTLMSAYKNIKMDQFMYYVIKEKGEVYEALRTFFRKREGGSAG"
     gene            5683..6402
                     /locus_tag="C1I60_RS14400"
                     /old_locus_tag="C1I60_14430"
     CDS             5683..6402
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686783.1"
                     /locus_tag="C1I60_RS14400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14430"
                     /product="response regulator transcription factor"
                     /protein_id="WP_137062357.1"
                     /transl_table=11
                     /translation="MEEIAVLIVDDEQGLRDMLTMVLKKEGFLHVKHAATGQEALQVVM
                     ESQIDVIVLDVMLPDSDGFEVCRHLRLYTEAPILFLTARDTDLDKLMGFGIGGDDYITK
                     PFNPLEVVARMKARMRYRKVPTVAMKPSLRTLDFGYFRLELESGVLYVEDKQVDCPARE
                     WLLLVFLCKHPNRIFSVRQLYEAIWSEAFLGDEKTVVIHISRLRKKIEPEPKQPQFLIN
                     VRGLGYKMMSVKREEQE"
     gene            6399..7481
                     /locus_tag="C1I60_RS14405"
                     /old_locus_tag="C1I60_14435"
     CDS             6399..7481
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686784.1"
                     /locus_tag="C1I60_RS14405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14435"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_137062358.1"
                     /transl_table=11
                     /translation="MNPLVKMSFRFMKVTLCFVLAYVLCFVFCTIIYIFIKSTFAASHG
                     ASQNINIDLFWTGLGIVQSIVFIAAYGWYIGKPLIYMMKWIGNISTGEFQAPLSELKLR
                     ERKKNRENSYKLPYQLYRELFEQMNILSAQLRRNEEERVEIEKRKQQWVAGVSHDLKTP
                     LTYIEGYAAMLTAQEYDWSDEERRSFSICISEKVTEMKQLIQDLNASMQFKESSLPIQL
                     KEEDIVEFLRNAVIDIANHPSAEQYEFSFTSMEATCIMLFDSKLLGRALQNFLINAIIH
                     NPPGTHVSMEVNKANDKLHIFIEDDGIGIIPNEFMRASHSKGHGIPIAKSFIEAHNGTL
                     HILPGSKTGTRMEISLPLNI"
     gene            7624..8547
                     /locus_tag="C1I60_RS14410"
                     /old_locus_tag="C1I60_14440"
     CDS             7624..8547
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426675.1"
                     /locus_tag="C1I60_RS14410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14440"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137062359.1"
                     /transl_table=11
                     /translation="MSEYVIHTQQLTRRFGKREFVKRLNLQVPGEQIYGFLGPNGAGKT
                     TTIRMLLGLIKSTAGEIEIFGKKLKDQRMEILKDVGSLVESPAYYAHLSAYRNLEIVTT
                     MRGLPTRRIHEVLDLVRLSKDAYRPVKGYSLGMRQRLGIAMALISNPKLLILDEPTNGL
                     DPSGIQEIRELIMNLPGAYGMTVLVSSHLLSEIEQIATYVGIINQGEMIFQGTMKELTA
                     KSKPQLFIETQDPVLAAGALIQHGWTAGAESMEPKEVVTPIVDRQQSSEMIKVLVEHNH
                     PIYRVTEKKKTLEEIFLELTGKERSL"
     gene            8544..9251
                     /locus_tag="C1I60_RS14415"
                     /old_locus_tag="C1I60_14445"
     CDS             8544..9251
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370164.1"
                     /locus_tag="C1I60_RS14415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14445"
                     /product="ABC transporter permease"
                     /protein_id="WP_137062360.1"
                     /transl_table=11
                     /translation="MILRVIKAEGFKLKKICWWLPLLQGCVLTGMTAVEWYLYFRQGPG
                     GVYAGFAVMFMFLSFVMLLGGTLLASIMAGTEHDTDTWKQLMAMPVPRSYIYLSKIVWI
                     VILQFGTALITIAGMSLIWMLYTNEPIPWRIMLLQPINASLATLPVLAIQLWLSTLFTN
                     QAFPLAFGIFGSIASLFLARTSILWIKILPWSYPALSSPLIKEHMIWVIVALSAGIIFT
                     GLGTLQFTKHEFK"
     gene            9266..10000
                     /locus_tag="C1I60_RS14420"
                     /old_locus_tag="C1I60_14450"
     CDS             9266..10000
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013370165.1"
                     /locus_tag="C1I60_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14450"
                     /product="ABC transporter permease"
                     /protein_id="WP_137062361.1"
                     /transl_table=11
                     /translation="MGSILRVETIKLQWIMVWILIILDAVINSLLGVLELNDLKQFFSP
                     SWLTLYTYSAQFHSMFFYPLYCGIIASLLCAYEHRDGGWKILLSSPYPRQQIYYAKYIL
                     LILILGLDQLIFIVGYFVSGNIAGAPGEIPWSVVLSTGLGGWLGIFPLAALQLMLSIKI
                     RNFGASLGMSICCVVPNIVITGFHSTIGAWFPFTIPYYIMMPQTATYAPRVEPYSLGLI
                     VIFTFLAYLYGGRKMFVNRDWL"
     gene            complement(10001..11362)
                     /locus_tag="C1I60_RS14425"
                     /old_locus_tag="C1I60_14455"
     CDS             complement(10001..11362)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309464.1"
                     /locus_tag="C1I60_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14455"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_137062362.1"
                     /sec_met_domain="LANC_like (E-value: 2.1e-54, bitscore:
                     177.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMDSFVMQQSDQARARDISKKIAFRLCDPESVYTAVHAEHNVSP
                     ETKYHPWGGTSLSHGYPGNIHLLSQWRATDSSYDWNGAIHLNMAQIQASLAKNGLNDVS
                     LYSGWAGIASSVSEASNHGEYYSNFLHQIHQWMIPLTKQWLQSNTEQLGLHEGMPMQAF
                     DTISGASGIGRYILKSSTDPICTPLVEPILQFLTHLTHPIHIHSRYVPGWYSPQKFQFL
                     GRDKRNYPLGNFNCGMAHGIPGPLALLSVAYSAGIEVTGQYQAIESITEWLLKYKHEDT
                     YGFYWPHIVPFEAETGSLEFDFQRAREAWCYGTPGIACSLFLAGKALHNDDLQKLAVKA
                     CISAISYEMAEREMDSSALCHGLAGLLMISWRMWCHSKEPALIPLVQQLSSRLLDRFQA
                     DSPLGFLDPEPKADGSQIWLSKAGMLEGVAGIAATLLGVSENKELAWDYILMLS"
     gene            11560..11712
                     /locus_tag="C1I60_RS14430"
                     /old_locus_tag="C1I60_14460"
     CDS             11560..11712
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820476.1"
                     /locus_tag="C1I60_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14460"
                     /product="FDLD family class I lanthipeptide"
                     /protein_id="WP_137062363.1"
                     /sec_met_domain="TIGR03731 (E-value: 7.1e-07, bitscore:
                     22.5, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNQFDLDLQVAKNEVAPKEVQPASGLICTPSCATGTLNCQVSLT
                     FCKTC"
     CDS_motif       11560..11631
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKNQFDLDLQVAKNEVAPKEVQPA"
                     /locus_tag="C1I60_RS14430_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       11632..11712
                     /prepeptide="core"
                     /locus_tag="C1I60_RS14430_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="5.70"
                     /molecular_weight="2508.0"
                     /monoisotopic_mass="2506.2"
                     /core_sequence="SGLICTPSCATGTLNCQVSLTFCKTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKNQFDLDLQVAKNEVAPKEVQPA"
                     /leader_location="[11559:11631](+)"
                     /alternative_weights="2526.0"
                     /alternative_weights="2544.0"
                     /alternative_weights="2562.0"
     gene            11786..13048
                     /locus_tag="C1I60_RS14435"
                     /old_locus_tag="C1I60_14465"
     CDS             11786..13048
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820475.1"
                     /locus_tag="C1I60_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14465"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_137062364.1"
                     /sec_met_domain="LANC_like (E-value: 3.7e-57, bitscore:
                     187.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKDLQGRSVEISKYIAQKLTDLSYTEKIVIHKNNLSPSRGVAPW
                     NPGSLADGVPGVLVLLAEWGYLEPDQYWAEHVHAQLLYLHSNSLLLLPHTSLYYGTTGV
                     AYGILLASNNRDNYNQLTSQLNKHIEVEWGKFPLISSTKEFSKQMDFINGLLGVGRYTL
                     EIPEDKAMRDLSRQLLDTITCFIPEYIHLTSRVGSASIHLGLAHGITGILALLVTALQK
                     KIEVEGIHEAIKHIADFLLIQIQEDQYGLYWPVNSQVASINKIENKEGMREIEGWCHGT
                     FGIAWTLFRAGNECSNEEWKKIAEKAVESIFCLDDELLNALSPTFCHGLAGLLHMAHRF
                     YYLTGNIAALHFADQIALKLVNLYDEELPFGYQDLEGTTHVHNIGILQGATGIALSLLD
                     YGIGKEQPKYSGRWSELFLIS"
     gene            13099..13776
                     /locus_tag="C1I60_RS14440"
                     /old_locus_tag="C1I60_14470"
     CDS             13099..13776
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820474.1"
                     /locus_tag="C1I60_RS14440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14470"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_137062365.1"
                     /transl_table=11
                     /translation="MKHKFMVISSFKKIKHFFETLRTPENVQIMFYDSLYQALPEIDEQ
                     CIGVALNQDHVTLEDLSYWHTVKEKFTVPFIFLSYHCDDKRQLDLLNQLFSMASSEYGM
                     ERDQEVISLSPNVIFDPAGKVIWNQGHEHMLTMMEFRLLMYLLTARERALTIDHIIDRV
                     WGVDAFTTSNTVYVHIRKLREKIEDDPSHPKILVTCHGIGYKLNIFPENLEVVSCEEPT
                     ALH"
     gene            13751..17011
                     /locus_tag="C1I60_RS14445"
                     /old_locus_tag="C1I60_14475"
     CDS             13751..17011
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820473.1"
                     /locus_tag="C1I60_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14475"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_137062366.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-186,
                     bitscore: 615.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.8e-14,
                     bitscore: 46.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.3e-49, bitscore:
                     160.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSQLHYTDTHKLHKEERVKDERWFSACDFFLIRAPLLPIDQYFQ
                     VFSGQDLDSKLTLEEITRKLKLVSQEAVIQEAISLASPSLMQFLHYLNDDNALDDKGEL
                     QKYEKTLNSFYRYFIRMTTRTTPFGLFSGVGQGICGKSTHLDIGTYNKHLKRARPDMEW
                     IYKLIQKIEADPAIFNQLKVSLNKTVMIKGNRAKLPFRPKHGAAEADDSAEIFSSIHLS
                     DVVRLTFEATEFPIQVMELKEILLKAFPDATMEIIVNYLRQLVEQEFILSELRPPLMDH
                     SSFHYIMEKIKKLDVTDQWIHNLHEIDTLLLRYNQCTIGEGADVYRKLSSKMLNIISVK
                     TPVQVDVKLEKEVTLPRHVLDDAAIGAEIMCRLYAPPQTYELAEYLNRFLEKYGVYQEV
                     PINELFDEDWGLGIPEMYRTNIEKSSMEDVGAFKRNAILFQWVANAISNHEIELILTDE
                     QVEELTVFDNFEASPETMEIYYSIYANSPEKVDSGDYALLLGASAGSNRAGKTFGRFLD
                     MFNEEFVQKFSEVYDHHRCFHPEALLSEMVFMPEQGKISNISLSKNLMEYEIVSGTTSS
                     KDKEHTLHIDDLLVGATLDRFYVKSKSLGKEIIPLQTHMLNYKLSPHIFRFLTDVTNKE
                     IGMWSYFNWGPLEQSPFLPRLVYKKVIISAAQWKLSKATLNISKLSEPKKGEELFHTWR
                     QQWNVPRYVYLTMGDNRLLLDLCNLFHVKELLRELSKTRDGQALLLTECLGDPSHTPLH
                     GAAGKYMGEFVFPLKKKNIKVKPGIPSSHNKIALQNFTTHTPVSMNRGIFPGGDWLYLK
                     LYGVKERETDLIGLSLGQLLYKPDFEDWSEKAYFIRYVDPEHHIRLRFQGDPDKLWTTG
                     LAQLNQWAVQMREEGLITNMILDTYLPEIERYGGQTLMELAEQVFDIDSKWVVSYLGGV
                     RSKFFNLDVEIAAVINIIHYLSGFGLTIQQQVDWLEERIDSKPHMKAFRDIKKTLITSV
                     EPNYEWIRQADMVSQTAFLELVEKRQASIERYAQAITLAKNNNVLTNHPNDILGSVIHM
                     HLNRLLGVNREREMKCMALAKHTLANLLHRKGVGHVTV"
     aSDomain        14303..14581
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1I60_RS14445_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.40E-15"
                     /identifier="RREFam001.1"
                     /label="C1I60_RS14445"
                     /locus_tag="C1I60_RS14445"
                     /protein_end="277"
                     /protein_start="184"
                     /score="46.2"
                     /tool="antismash"
                     /translation="LNKTVMIKGNRAKLPFRPKHGAAEADDSAEIFSSIHLSDVVRLTF
                     EATEFPIQVMELKEILLKAFPDATMEIIVNYLRQLVEQEFILSELRPP"
     gene            16998..18890
                     /locus_tag="C1I60_RS14450"
                     /old_locus_tag="C1I60_14480"
     CDS             16998..18890
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309469.1"
                     /locus_tag="C1I60_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14480"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137062367.1"
                     /transl_table=11
                     /translation="MSQSNGQKNDLVSLSYKNIFRTFLFWPRIFRLLWDTHPAFLIAIL
                     ITNLFKGAIPAVILLATRELINSVVGGVSGGSFQPVFIAFGVLIGINIVYDLISIGESF
                     FRKMFQSQLSNQVNIRLIEKAQKMSLQSFEDADVQNMLQRAQGEADYRPFEIFTQILAI
                     ISSVVTLFSVGAILIAWKWWAFLFIFLIPCLSFYSFLRIGQREFNVHFQRAGRQRESWY
                     LSFLVTRDNSFKEVKIFQLGDYLRKRYKTILEGFYREDKVLAVRRSYTSLVFQIVNQGA
                     GGFIIFMAVQATFVGQILVGNLVSLIQAITLTQSTSQSIVQGILSLCQNNLYIKQLFDF
                     LDMPEEAETQTINQSLSAIQSIEFRNVSFRYPNTEVNAISNVSFTLSQGEKLAIVGRNG
                     SGKSTIVKLLTHLYSEFEGEILINGHSIHEMDKDSFREKIGVVFQDFVHYEMAVRDNIG
                     FGNVSSREMDEDIWTAIDKAGITDLVVSLPDKIDTLLGKWFEDGQQLSGGQWQRIAIAR
                     AFMRNADVYVLDEPSSFLDPHAEKEVFQKFDQLVNEKLGVFISHRLSSARMADTIILME
                     EGKIIETGSHEYLLDMNGVYAEMFRLQASSYLPQRECDFQEENTSPSLVRTTGG"
     gene            complement(18934..19263)
                     /locus_tag="C1I60_RS14455"
                     /old_locus_tag="C1I60_14485"
     CDS             complement(18934..19263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820471.1"
                     /locus_tag="C1I60_RS14455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14485"
                     /product="AzlD domain-containing protein"
                     /protein_id="WP_137062368.1"
                     /transl_table=11
                     /translation="MNIDPNVMYIIIGGMVVTAIPRIIPFVVLQKLALPKPVLQWLSYI
                     PICIFTALVMEHLLVRTEGSVTFNWQVLIAILPTLVTALWSKNLLATVIVGIVSMAVIR
                     LLWMG"
     gene            complement(19260..19985)
                     /locus_tag="C1I60_RS14460"
                     /old_locus_tag="C1I60_14490"
     CDS             complement(19260..19985)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:1902495 - transmembrane transporter
                     complex [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016820470.1"
                     /locus_tag="C1I60_RS14460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14490"
                     /product="AzlC family ABC transporter permease"
                     /protein_id="WP_137062369.1"
                     /transl_table=11
                     /translation="MSIASGLSETERDPLHFLQGVKDCIPTLLGYVCIGFAAGIVGASS
                     GVGTMEIALMSALVYAGASQFIMCSMLAASSPPSVIILTTFIVNARHLLLSASLAPYFS
                     KYSLWKNIGIGVLLTDESFGVASDKLAKGGQVSDRWMNGLNITAYLVWIASCVAGGILG
                     NWISRPEAFGLDFALPAMFLALLISQLQSVQISKLKHRLLLVLCMAVLMYLLSWWVPSH
                     IAVIVATVMTATIGVLTDK"
     misc_feature    20082..20095
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.05"
                     /tool="antismash"
     gene            complement(20257..21249)
                     /locus_tag="C1I60_RS14465"
                     /old_locus_tag="C1I60_14495"
     CDS             complement(20257..21249)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309481.1"
                     /locus_tag="C1I60_RS14465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14495"
                     /product="carbohydrate kinase"
                     /protein_id="WP_137062370.1"
                     /transl_table=11
                     /translation="MKNVGTVLCVGELLIDFFCTDIDVNLAKGQHFSKQAGGAPANVSA
                     AVAKLGGKASFLGKVGADPFGMYLKQTLDEQHVDTSMLLFDPATPTTLAFVSLAANGER
                     DFVFNRGADRQLSLQDIDREWTRQAAILHFGSATALLADPFQEAYLSLLDEAKANGQFT
                     SFDPNYRGDLWKDRLEEFIALSRRGIHNADLVKVSEEELNIITGLADRNASLDLLHGLG
                     AKTVAVTLGKEGTLISSGVSRSLIGSIAVKSIDSTGAGDAFVGAMLYQISQLSQPKAFT
                     TNWKQQQEFVTLANQVGAIVCTKVGAIAALPSMEEVKRFVEQGESRIEA"
     gene            complement(21272..22306)
                     /locus_tag="C1I60_RS14470"
                     /old_locus_tag="C1I60_14500"
     CDS             complement(21272..22306)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309482.1"
                     /locus_tag="C1I60_RS14470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14500"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_137062371.1"
                     /transl_table=11
                     /translation="MTRKSKVTIQDIADALGISRNTASKALNGVENIPAVTRDKVIKKA
                     VELKYKQFSYMETASEKQGNIALLTCNLPNSSHFGSLLISGLEKEISNQGYTLSIYFVR
                     ENDINTMTLPGNFEPSNVAGIFCIEMFSKEYSKLITDLGIPTIFIDCAADMVYPELKAD
                     LVLMENEHSTYCLTRKLIDHGYESFGFVGDYNHCKSFNERWTGFNKALAEAEITLDPAH
                     SIVAPDRNFFIEENWMEQQLDALRECPSIFICANDFIAISVIKSLKNKGIKVPEDVAVC
                     GFDDASESRVVEPHLTTVHIYSSQMGIISAEMLLSRIKDNTMPYRVTHVATDIVYRDST
                     PVLN"
     misc_feature    complement(22446..22459)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.31"
                     /tool="antismash"
     misc_feature    22792..22812
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 26.6"
                     /tool="antismash"
     gene            22815..23699
                     /locus_tag="C1I60_RS14475"
                     /old_locus_tag="C1I60_14505"
     CDS             22815..23699
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821412.1"
                     /locus_tag="C1I60_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14505"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_252361723.1"
                     /transl_table=11
                     /translation="MVRNYILYLFLVPSIILTVIFKYVPMYGSIIAFKNFSPRKGIMGS
                     EWVGFEHFQRFLSSPNFYDILMNTLKLSAYGLILGFPVPIILALMLNLIRGAKLKKNIQ
                     LIVYAPNFISVVVVAGMLFVFLSPAGIVNALVTTFTGKPISFMTDPAYFRTVYILSGIW
                     QTAGWSSIIYVATLANVDPQLHDAATIDGASLMKRIFHIDLPALKPVMAVLFILAAGGI
                     MSIGYEKAYLMQTALNTPTSEIIATYVYKVGLQSGDYAYSTAIGLFNSVINVVLLIFVN
                     TVVKKLNEGEGLY"
     gene            23714..24595
                     /locus_tag="C1I60_RS14480"
                     /old_locus_tag="C1I60_14510"
     CDS             23714..24595
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014281709.1"
                     /locus_tag="C1I60_RS14480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14510"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_137062373.1"
                     /transl_table=11
                     /translation="MDIHYTGKDRILIIINYILLGLFVLAILLPLVYVVLSSFLTPNTL
                     ITKGFAITSSDWTLTGYAKILSNSAMIRGFFNAIFYSAAFAFATVLFSVFAAYPLAIEE
                     LVGKRPIMIFFLITMFFGGGLIPTYLVIKDLGMLNTVWAIILPGSISVFNIILAKTYFQ
                     GLPKELFQAASIDGASELSIFFKIVLPLSKPIIFVLALYAFVGQWNSYFDAMIYLDDPK
                     LFPLQLVLRSILIQNQVQPGMIADAMAQAELKKLSEMIKYSAIVISSLPLIVMYPFFQK
                     YFEKGVMVGSIK"
     gene            24614..26233
                     /locus_tag="C1I60_RS14485"
                     /old_locus_tag="C1I60_14515"
     CDS             24614..26233
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309485.1"
                     /locus_tag="C1I60_RS14485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_14515"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_137062374.1"
                     /transl_table=11
                     /translation="MKKTLLTLSVLVLSTSLLAGCGGSGNNSAASEDYKLENVTLPLKE
                     KVTLHFMTQSSPLAPSDPNEKMIYKRLEEKTGVHIDFTNFTSDSFIEKRNLAVASGDLP
                     DAILDAGYSDYDLLNLGKDGTIIPLEDLIDKYMPNLQKVLKEAPEYKSMITAQDGHIYA
                     FPWIEELGAGKESIHSVNDMPWINVEWLKKLGLKMPKTTEDLKNVLLAFKNGDPNGNGQ
                     ADEIPLSFMLNNGNEDLNFLFGSFGLGDNGDHTVVTNEGKVVFTADQDGYKEGIKYLNE
                     LYKLNLIDEESFEQDYNTYLAKGQNEKYGLYFQWDKANISGDNDKYELMNPLAGPSGKV
                     NVTRTNNLGFDRGRMVITSDNKNLELTAKWIDQLYDPIQSVQDNWGTYGDKTQQNIFEY
                     DEASHMLKHLPLKGTAPVELRQKTNIGGPLAILDEYYGKVTTKPDDAVGRLKLMKERLV
                     PFMKADHNFPKVFFSLEDQKQISTLETDLFAYVNRKRAEWIKTGKVEEEWAEYKAELSR
                     LGLDKWLEIKQKGYDRYLKDQG"
ORIGIN
        1 acttgacgag tatgttgaat tttgattccg tacatctgct caacgttcga taaaatcgac
       61 attttgatcc tcactttctg ttatgcatgg gcccattcct gcaaaatacg aatgatttgc
      121 aaacgaaggg gccacgattg atcccaattg tccaagatct cgcggtctct tgatcgagtc
      181 gggtgtaggg aggcgtgcca tgcttcacgt ggcagcttat ataaggctgt aaccattttt
      241 cgttcagttc ggcttagtgg tttgcgtttt tggtatccct tcagcaagga ttgcacaaat
      301 ttaggattga attgggtcgt attcataagg gccttcgcca gatctgcata gactgagccg
      361 accttaactc gatcccaatc aatgattttg agttgaccat catctgaaat catgacattg
      421 gggatcgtga tgtcgctgtg tatcaaagag gggaaacggt tttccttctg aagcagctta
      481 acaatggatg tatcctgcaa atccttccat gcctgtctag ctaaacgttt gcagtttttt
      541 ccatgagtgc tgtaccagtt gcggtattct ttgtcatgac gactgatttg tgttattttt
      601 cgttgaaaaa gacggtcctg ttttttccat attcgcaatt gttgtaacgt aggggatttc
      661 ccccttccaa tctgatgcaa gccagtggac gtggcgtgaa gcgtggcaag tgcccaccca
      721 agcttttcga aatcttcagc attttccaat ccccgcccct tgatccactg actcatataa
      781 aatggcgttc cttgaaataa agtccatagc ttcccggaat gtgttgggag ccacgcgggc
      841 atgtagctgt actttctctt tttcaaaagc ctgatcatgc ttgctgcctg ctccatctgc
      901 tggattgtat tggagtggat catcttagta cggttaaagg gctttaatgc ataagttccc
      961 tttttcgttt ttacctggat tactgcattt tttcggtaca tggatgagac caagcttgat
     1021 tttaacggga tcaggccaaa acgactggtg attttgcgaa tctgtgcttt ggtataggat
     1081 ttcgccataa gtacctcgct tgatttgtga ttaaataaaa aggtaatcct ctgttagtta
     1141 tcagtctatt catgatgagg taataggtgc tgttttaaag ggctatacac gttccttcta
     1201 gatttatgtt atatttcttt acattaaaaa aacgtctttt cctgaaaaga gcggtttatt
     1261 tgcgttccat tcggtaaaag gtttagtttt gtttattttt ttggtacact atcctgaaaa
     1321 ttaagttgag acgaaggtac taagcagaga gtgcgtcaac gctgggcaga cttatgatcg
     1381 gtcttgtggc agggaggaaa agacatggat aaaaaaatat taatagcgga cgatgagccc
     1441 ggcattcgca atgccttggc ctatgcgttg caaagagaag gttttttagt agaaaccgct
     1501 gttgacgggg aggacgcatt ggaaaaagtc cgtttgtttc acccggatgt gctggtgctc
     1561 gatgtgatga tgcccaagct gggcggatat gaggtgtgcc gtcgtttgga aagtcggaag
     1621 ggcatcggta ttctgctgct gactgccaaa aacgatatcg tggacaaggt gctcgggctg
     1681 gaactgggag cggatgattt tatgagcaag ccctttgatc tgcgagagct gctcgcccgc
     1741 atcaaggcgc tggtacggag gctggaacgg gaaggagcac ctgcgccaga gggatcagaa
     1801 acgatacttg gcccgttgcg agtgcgtccg tccagcagga cggctgaact ggagggaaca
     1861 gtgctggagc tgacacccaa ggagtttgat gtgctggcac ttctggtgtc acacgccggg
     1921 cgggtgtaca cacgggacga gctgctgcag caggtatggg gtttcgatta tgcaggtgga
     1981 acacggacgg tggacattca catccagcgc ctgcgcaaga agcttgagcc ttatcagtcg
     2041 ttattgcaga cggtatatgg aattggctat aaggcggaaa agatgctgtg aacgaacggc
     2101 ggttgcttgg cgcttggccc atccactcac catgtcgatt cttaatccag gcggacacga
     2161 ggttcatcgt taacgagaaa gtcgtaccag cggttgcgaa aacgaacctg aggcccgtct
     2221 gcgggtacgt gcgcctccat acggagcgcc tcagggatag gacgcggatg ctggctttcc
     2281 accacggctc gatcctcttc cagcaccctg ctgctatatc tggaaaaaat ccggctcata
     2341 cccggtacaa atttggaaaa attacgtcca gccagcccgt agatggcggt cacctcctgc
     2401 tcaattgaaa caggtaccct gaaattggaa agaggctata tgaaattaat caatagaaaa
     2461 aggagtacct ccccaaatct cgaaagtgtt aagcaccaca caaaacacag agatgagagg
     2521 atggactcgc tatgtcatat attcgacacg agaggcaata tttatatgaa aagggataaa
     2581 agcacaacaa cccgattacg ccttcaaata tgcaactctg gatgctgggt atgattatga
     2641 gccgatctac gagcaaattc gccaagcaaa agctcatgcg atcatcgctt acaatcgacg
     2701 acgtgaatcc gaattaatgg gatttgatga gcatttttat tgtccaacta agtgtagccg
     2761 accaatattt ggtcccaata gagtgggtca agtgggttcc aaaggagtgg gcattttgga
     2821 ttctaattaa gaagtgtaaa aagacgcatt ccgttttttc ggactacgcc tttactttcg
     2881 ctatatactg gtcgtttgtt tctatacaac tatacaaact tgcgatgatg cttcttgccg
     2941 tcgtatgaga ataaggccag cttgccttca atcatcgttt ccaaatgaac ggtccgcccc
     3001 cataactgat acacatacgg aagcgtacgc tccatatatt ttaaatccag ctcaatccct
     3061 tcaaactgat gcttgagctt caactcgcca gtgtgcagat aatctccatc ctcaacgacg
     3121 atataagggg agccgccatt cacacgcgag aatacgagct ggtcccgtat gttctcccac
     3181 gatttatctg tgattttcca atccggccct cgtttctcaa acacgtatag atccaaatcc
     3241 tctgtcagtt tcttggtcat gtaattgcgt ataaaagagg tgtctgagtc aaattcccgt
     3301 acctcgaaca ttttagcgcg tccttcgcct ggtttgcgtc cttgtcgatc ctgctcttca
     3361 cgggttgggt tatcccatcg cttttcaata tcctcaaata ttttaagccc caaataatac
     3421 ggattcaggc tttgcttgga aggctgtacg acagaagcgt tcagcagtgc aaattcaacg
     3481 gtttcatccc cggtcaaatc caattccctg acaatccgct gatgccaata ggaggcccag
     3541 ccttcattca taattttggt ctccatctgg ggccagaaat acagcatttc gtcccgcagc
     3601 atcgtcatga tatcccgctg ccagtcctct agcacttccg aaaattcctg aataaaccag
     3661 acgacatcct tctccggttc aggcgggaac tgtcgtatct gtatgcctcc gctttccgtc
     3721 gaatccggct gtggcttcac cgtgtccagt gaccacagat catcgtaagg accgtctggg
     3781 cgctgccgtt ttcccggttc cttttgttca cggactttaa gctccatata gcgctgttta
     3841 tccagatgtt gtggtttgat caactgcgga tcaatatgtt cctgtatagc cagtaccgaa
     3901 tcaatgaagg attcgacggc cttcgaaccg tattccattt cataaccgct gatccggtct
     3961 gctgtggcgg acatactctc caccatattg cggttggagg ccgagaagcg ggcattgtgc
     4021 ttgaaaaaat cacagtgcgc cagcacatgg gcgacaatca gtttattctg aaccaaagaa
     4081 tttccctcca gcaggaaggc gtagcaggga ttggagttga taaccaactc atagattttg
     4141 ctcaggccaa aatcgtactg catcttcatt ttatgaaatg tttttccaaa gctccagtgg
     4201 ctaaaccgag tgggcatccc gtaggctcca aacgtgtaga caatatcggc cgggcaaatt
     4261 tcataccgca tcggatagta gtccagcccg aatccgctgg caacttccat aatttcagca
     4321 atggcgtatt ccagctcccg atggtcactg ctcatccagc gctcccccct tcccgtttgc
     4381 gaaaaaaggt gcgtaaggct tcgtatacct cgcccttttc cttgatgacg taatacatga
     4441 attgatccat cttgatgttc ttataggccg acatcagtgt gctgctgcgg ttatattgat
     4501 tcacttctcc atagccgaac atgttgctgc gcttcataag ctcctcgatt aacttcacgc
     4561 accgctcgtt gtccgaggtc agattgtcgc cgtcagagaa atggaaggga taaatattat
     4621 agctggaagg aggatagcgc ttgtcgataa tctccaatgc cttgagatag gctgaagagc
     4681 agatcgtgcc accactttct ccacgagtga aaaattcctc ctctgtaacc tctttggctt
     4741 cggtatgatg cgccagaaag acaatctcca ccttttcata ttgacggcgc aaaaagcggg
     4801 tcatccagaa aaagaagctg cgggcgcaat atttttcaaa agatcccatc gagccggaag
     4861 tatccatcat cgcaatgatc acagcgttgg attgagggat ggttttttcc tcccatgttt
     4921 tataacggag atcgtcagga ctgatatgat gaatgcccgg cttcccctga cgagcgttgc
     4981 gacgcagatt ttcgagaatg gttcgcttct tgtcaatgtt ggcctgcatg ccttttttgc
     5041 gtatatcatt gaatacgata gactcaacct caatctgttc cttgtctttc tgctgcaaat
     5101 gcggtaattc catatcctcg aacagcatat cttccagttc ttccatgctg acttctgtct
     5161 ccatgatatc gtgtccaggc tggtctccgg ccttctcgcc tttaccgggc ttctgggaag
     5221 caggatcgcg tccgatgaca tcgcccacct gactgtcgcc atccccttgc cctacatgct
     5281 tttgcttctg ataattataa atgaagcgat attcgtccag actgcgaatc ggcactttaa
     5341 taatctgctt accgtctgac atgataatat tttcttccgt aatcagatca ggcagatttt
     5401 gcttaatcac atctttgacc ttctgctgat gacgctgctg gtcttggtac cctttgcgat
     5461 gcagcgacca atcttcgcgg gatacgacga atgaatatgg ctgacgtggt tccggcattg
     5521 ttaggcaccc cccaagtgga tacacggcac agtttggcct tgttggttat taagtatatt
     5581 cacggggatg tacgatatgt gatggaactc gatttaaatt ctgcccgttt gcttttataa
     5641 tgaaagtaaa aaatgtaaaa aaagaatgga gaaccttgag ttatggaaga aattgcagta
     5701 cttatagtag acgatgaaca ggggctgcgg gatatgctga caatggtgtt aaaaaaagaa
     5761 ggattccttc atgttaagca tgcagcaacg ggtcaggaag cgctgcaagt cgtgatggaa
     5821 tctcagattg atgtgattgt gcttgatgtt atgctccctg atagcgatgg gtttgaggtg
     5881 tgtcgtcatt tgcgtctata tacggaagct cctattcttt ttttgacggc aagagataca
     5941 gacctggaca aattaatggg atttggtatc gggggggacg attatattac caaaccgttt
     6001 aaccctctgg aagtcgttgc gcgtatgaaa gctcgaatga gatatcggaa agttccgact
     6061 gtggccatga aaccgtcctt acgcacttta gattttggat attttcgtct ggagttggaa
     6121 tccggtgtgt tgtatgtgga ggacaagcag gtcgattgtc cggcacgtga atggctactg
     6181 ctggtatttt tatgtaagca cccaaaccgt attttcagtg tacggcagct atacgaggcg
     6241 atatggagcg aggccttctt gggtgatgag aagactgtag tgattcatat ctcccgttta
     6301 cgaaaaaaaa tagagcctga acctaagcaa ccgcaatttt taattaatgt aagaggactt
     6361 ggttataaaa tgatgtcagt caagagggag gagcaagaat gaaccctctg gttaaaatgt
     6421 cctttcgttt tatgaaagta acgttatgct ttgtactggc ctatgttctt tgttttgtgt
     6481 tctgcacgat catatatatt tttataaaaa gtacatttgc tgcatctcat ggtgcatctc
     6541 aaaatataaa tattgatcta ttctggacag gacttggtat cgtgcaaagt attgtattca
     6601 tagctgccta tggatggtat attggtaagc cactaattta catgatgaaa tggattggaa
     6661 atatatcaac gggggaattc caagcgcctc taagtgagtt gaaactgcga gagcgtaaaa
     6721 aaaatcggga aaatagttat aagctcccgt atcaattgta tagagagctt tttgaacaaa
     6781 tgaacatatt atctgctcaa ttgcgccgta atgaggagga gagagtggaa atagaaaagc
     6841 gaaaacagca gtgggtagca ggcgtaagcc atgatctgaa aacaccgtta acctatatcg
     6901 aaggatatgc agccatgcta actgcccaag agtatgattg gtctgatgaa gagagaagaa
     6961 gctttagcat atgcatcagt gaaaaagtga cggagatgaa gcagttgatt caggatctaa
     7021 atgcttctat gcagttcaag gagagctctc tgccgattca attgaaggag gaagacattg
     7081 tagagtttct gcgcaatgca gtcatagata tcgctaacca tccttcagcc gagcaatacg
     7141 aattttcttt tacgtcaatg gaagcaacat gtattatgct ctttgatagc aaattattag
     7201 gtagagcgct acaaaatttt ttaattaatg cgatcatcca taacccacca ggtacacatg
     7261 tttcaatgga agtgaacaaa gcgaacgata agcttcatat ttttatcgaa gatgacggca
     7321 taggaataat tccaaatgag ttcatgcggg cgtctcactc caaaggtcat ggaataccta
     7381 ttgccaaaag ctttattgaa gcgcataacg gaacgcttca tatccttcca ggaagtaaaa
     7441 cgggtacaag gatggagatt tcattgccgc taaacatcta acttttcaac atctgatctc
     7501 acattttgaa gcttgcttgt ttttttgcct gctgtttatg aactgtttac ttgatgttaa
     7561 ctttacttca gtaaactata tgtaactaaa acttcagcat taaaagtcga gaggagatag
     7621 gaaatgtctg aatatgtaat acatacacag cagctaacta ggcgttttgg aaaacgggaa
     7681 tttgtaaaac gattaaatct ccaggtaccc ggagagcaaa tttatggatt tttaggacct
     7741 aatggggcag gtaaaacaac cacgattcgt atgctgctcg ggctgattaa atccacagct
     7801 ggagaaattg agattttcgg gaaaaagcta aaggatcagc gtatggaaat tttgaaggat
     7861 gttggttcct tggttgaatc acctgcctat tatgctcatt tatccgcata tagaaatttg
     7921 gaaatcgtta caacgatgcg tggactgccg acacgaagaa ttcatgaagt gctggatttg
     7981 gtgagattaa gcaaggatgc gtatcgtccg gtaaaaggat attccttggg gatgcgacaa
     8041 agactgggga ttgccatggc acttatttct aatcccaaat tgttgattct tgatgaaccg
     8101 acgaatggtt tggacccgtc aggtatccag gaaattcggg agttaattat gaacttgcct
     8161 ggcgcttacg gaatgacggt actggtttcg agccatttat taagtgagat tgagcagatt
     8221 gcaacctatg taggaattat taatcagggt gaaatgattt tccagggaac gatgaaggaa
     8281 ctcacagcca aaagtaagcc tcaattattc atcgaaaccc aagatcctgt tctggctgca
     8341 ggagcactga ttcagcatgg atggacggct ggagctgaat ccatggagcc caaagaagtc
     8401 gtaactccta ttgtggatcg gcaacaatct tcggagatga ttaaggtgct tgtggaacac
     8461 aatcatccca tttatcgggt aacagaaaag aaaaaaacat tggaggagat attccttgaa
     8521 ctgacaggta aggagcgaag cttatgatac tccgggttat aaaggcagag ggattcaagc
     8581 taaagaaaat atgctggtgg cttcctcttc tacagggctg tgtacttaca ggtatgactg
     8641 ccgtggaatg gtatctttac tttcggcaag ggccaggagg tgtctatgct ggttttgctg
     8701 ttatgtttat gtttctctcg tttgtgatgc tgcttggcgg tacactttta gcgagcatta
     8761 tggcgggtac agagcatgat actgatacat ggaaacagct tatggccatg cctgttccca
     8821 gaagctacat ctatttatcc aaaatagtat ggatcgtgat tctacagttt ggtaccgcct
     8881 tgatcactat agcagggatg agccttatct ggatgctgta tacaaacgag ccaattcctt
     8941 ggcggattat gctgttgcag ccgattaatg caagcttggc tactctacca gtactcgcaa
     9001 ttcaactttg gctttctacg cttttcacta atcaagcatt cccattagcg tttggtatat
     9061 ttggttctat tgcaagcttg tttttggcac gcacaagtat tctatggatt aaaatattgc
     9121 cttggtcata ccctgcacta tcaagccctc tgattaagga acacatgatt tgggtgatcg
     9181 ttgctttaag tgcagggatc atctttacgg gacttggtac attacagttt accaagcatg
     9241 aattcaaata gagaggagaa gctacatggg ctctatttta cgcgtggaaa cgataaagct
     9301 tcaatggatc atggtatgga ttctcattat attggatgcg gtcataaatt ctttattggg
     9361 agtcttggaa ctgaacgatt tgaagcagtt tttttcgcct agctggttaa ctttatacac
     9421 ctattcagcg caatttcact ctatgttttt ttatccgctc tattgtggaa ttatcgcttc
     9481 tcttttgtgt gcatacgaac atcgagatgg gggatggaag attttattga gcagtccgta
     9541 tcctcgccaa caaatctatt atgcaaaata tatattgctc attctcatac tggggcttga
     9601 tcagcttata ttcatagtag gctattttgt aagtggaaat atagcaggtg ctccaggaga
     9661 aatcccttgg tctgtcgtcc tttctaccgg tttgggaggg tggctcggga ttttccctct
     9721 agcagcacta cagcttatgc tctcgataaa aatccggaat tttggagctt ctctgggaat
     9781 gtccatttgc tgtgtggttc ctaatattgt cataacaggc tttcattcta ctataggtgc
     9841 gtggtttcct tttacgattc cttattatat catgatgcct caaacagcga cttatgcacc
     9901 cagagttgag ccttatagcc ttggattgat tgtgattttt acgtttttag cttatctgta
     9961 tggtggaaga aagatgtttg tgaataggga ctggttgtag ttaggatagc attaggatgt
    10021 aatcccaagc tagctccttg ttctcagaaa cccctaataa agtagcagca attccagcaa
    10081 cgccttcaag catgcccgct tttgacagcc agatctgaga gccgtccgcc tttggctcgg
    10141 gatcaagaaa tccaagtggg ctatccgctt gaaagcgatc aagtagacgg ctcgataatt
    10201 gttggacaag tgggataagc gcaggctcct tactgtgaca ccacattcgc caagatatca
    10261 tgagtagacc ggcaagaccg tgacagagtg cagaggagtc catttcccgt tcagccatct
    10321 cataggagat tgcactgata caagctttta cagccaattt ttgcagatca tcattatgga
    10381 gagcctttcc ggcaagaaat agggaacagg cgatgccggg tgtaccgtaa caccatgctt
    10441 ctcttgctcg ttggaaatca aactctagtg accctgtttc agcttcaaat ggaacaatat
    10501 gaggccagta gaagccgtat gtatcctcat gtttatactt aagcaaccat tccgtaatgg
    10561 attcaatcgc ttgatattga cctgttactt caattccagc actgtatgca acggataata
    10621 aagccaacgg accaggaata ccatgtgcca ttccacaatt gaaattaccc agaggatagt
    10681 tacgtttatc ccggcctaaa aattgaaact tttggggaga gtaccaccct gggacataac
    10741 gactgtgaat atgtatggga tgtgtaagat gagtgagaaa ttgaagaata ggctcaacaa
    10801 gaggagtaca gatggggtcg gttgaactct tcaaaatata tcttccaatc cctgaagctc
    10861 ccgaaatggt gtcaaaggct tgcataggca tcccttcgtg tagacctaat tgttctgtat
    10921 tcgactgaag ccattgtttc gttagaggaa tcatccattg atggatctga tgtaagaaat
    10981 tgctgtagta ttcgccatga ttggaagcct cactcacgga agaagcaata cctgcccatc
    11041 cactgtaaag cgagacatcg ttaagaccat ttttagcaag tgaagcttgg atttgagcca
    11101 tgttcaagtg tatagcccca ttccaatcat acgaagagtc tgtagcacgc cattgggata
    11161 gtaaatgaat attaccagga taaccatggg aaagtgaagt tcctccccaa gggtggtact
    11221 ttgtttccgg cgaaacattg tgttctgcat ggactgccgt atagacggat tcgggatcgc
    11281 atagacggaa ggcaatcttt ttactgatat ctcttgcacg agcttgatcg gattgttgca
    11341 taacaaaact atccattgtc atatgaatgc cccctttatt tttttctcat taatattgtc
    11401 gctaaaagct gctgagttgt ccttaaaaat actaaaaagt aacgaaggtt tatcttaaat
    11461 gtactcgttg aaattaagac aaatgtaaga attttataaa gtctagttaa gattatataa
    11521 cttataatga aattgtaaaa aataaaagga ggtaacaaga tgaaaaatca atttgatctg
    11581 gacttgcaag tagctaaaaa tgaggttgct cctaaagagg tccaaccagc cagtggtctt
    11641 atctgtactc cttcatgtgc aacaggtact ttgaattgtc aagttagtct taccttctgc
    11701 aaaacgtgtt gataacgaga aaatatggaa aaaaggcacg gtttctatta ccgtgtcttt
    11761 tcccatatga atatggggag gatttatggt caaagatttg caggggagat cagttgaaat
    11821 cagtaagtat atagcacaaa aactaacaga cctatcatat acagaaaaga tagttattca
    11881 taaaaacaat ctctcacctt cacgtggagt ggccccttgg aatccgggct cgcttgccga
    11941 tggagttcca ggtgtattag tgttgttggc cgaatggggt tatctggagc cagatcaata
    12001 ttgggcagag catgtgcatg ctcaattgct gtacttacac tctaactctt tattattgct
    12061 gcctcatact tctctttatt acggaacaac aggagtggct tatggcatac tgttagcttc
    12121 caataacaga gataactata accaactaac gtctcaactg aataaacata ttgaagttga
    12181 atggggaaaa ttccctctga taagctcaac aaaagagttc agcaagcaga tggatttcat
    12241 caatggactg ctcggagttg gcagatacac attggagatt cctgaagaca aggcgatgcg
    12301 tgatctgtct cgtcaattat tggataccat tacgtgcttc atacctgaat atattcattt
    12361 gacgtcaaga gtaggttcgg cttcaatcca tctaggtttg gcgcatggta ttaccggaat
    12421 acttgcactg cttgtcactg ccctacaaaa aaagatcgaa gttgaaggaa tacatgaggc
    12481 tataaagcat atagccgatt ttttgcttat tcaaattcag gaggatcaat atggtttgta
    12541 ttggcctgta aactctcaag tggcttcaat aaacaagata gagaacaaag aaggaatgag
    12601 agaaattgaa ggctggtgcc atggaacctt tggaatagcc tggactctat tcagagcagg
    12661 aaatgagtgt agtaatgaag aatggaaaaa gatagcggaa aaagctgtgg aatccatatt
    12721 ttgcttagat gatgagctat taaatgcgtt atcccccact ttctgtcacg gattggcggg
    12781 tttgcttcat atggctcata gattctatta cttaaccggt aatatagcag cgttacactt
    12841 tgccgatcag atagcattaa agttagtgaa tttatacgat gaagagcttc cgtttggata
    12901 ccaggatttg gaggggacaa ctcatgttca taatatagga atactgcaag gggcaacagg
    12961 gattgcatta agcttgttgg actatggaat agggaaggag caacctaaat attcagggag
    13021 atggagtgaa ttgtttctaa tttcgtagcg gctcggtctt aactgcttta tctgaagcat
    13081 tggttttggg gggattagat gaaacataaa tttatggtta tatcatcctt taagaaaatt
    13141 aagcattttt ttgagacttt aagaactcca gaaaacgttc aaatcatgtt ttatgattcg
    13201 ctttaccagg ctctaccgga gattgatgag cagtgcatcg gtgtagcttt gaatcaggat
    13261 catgtaacgc tagaggattt gtcttactgg cacaccgtta aagaaaaatt tacggtccca
    13321 tttatcttcc tgtcctatca ttgtgatgac aaacggcaat tggatctcct caaccaattg
    13381 ttttccatgg cttcatctga atatggaatg gagagagacc aggaggtaat tagtttatca
    13441 cccaatgtca tttttgatcc tgctggaaag gttatttgga atcaagggca tgagcacatg
    13501 ctgactatga tggaatttcg attattaatg tatctcctta cagcgagaga gcgtgcattg
    13561 acgattgatc acattataga cagagtatgg ggggttgatg cttttactac atctaatacg
    13621 gtgtatgtgc atattcgaaa attgagagag aaaatagaag atgatccaag tcatccgaaa
    13681 attttagtaa catgtcatgg aatcggttac aagttgaata tatttcctga aaatttggag
    13741 gtggtcagtt gtgaagagcc aactgcatta cactgatact cataaactac ataaagaaga
    13801 aagagttaag gatgaaaggt ggttcagtgc atgtgatttc tttctaatca gagccccatt
    13861 actaccgata gatcaatatt ttcaggtatt ttcgggccaa gatttggaca gcaagcttac
    13921 tttggaggaa ataactcgta aactaaagct ggtttcccag gaagctgtta ttcaagaagc
    13981 tatatcatta gcctctccgt cccttatgca gtttctacac tacttgaacg atgacaatgc
    14041 attggatgat aaaggagagt tacaaaagta tgagaagacg ttgaacagct tttatcgtta
    14101 ttttattagg atgactaccc gaacgacccc ttttggtttg ttctcgggag tagggcaggg
    14161 gatctgcggc aagtctaccc atttggatat cggtacctat aataagcatc ttaagagagc
    14221 tagacctgat atggaatgga tatataaact tattcaaaaa atcgaagctg atccagctat
    14281 atttaatcaa ttaaaagtct ccttaaacaa aacggttatg atcaaaggaa accgagccaa
    14341 attacctttt agacctaagc atggagcagc agaagctgat gattctgcag aaatttttag
    14401 ctccattcat ctctctgatg tcgttcgcct gacgttcgaa gctacagagt ttccaattca
    14461 ggtaatggaa ctaaaagaaa tactattgaa agcatttcct gacgctacta tggaaatcat
    14521 cgttaattat ttgaggcaac ttgtagagca agaatttatt ttgagtgagc ttagacctcc
    14581 gttaatggat cattcgtcct ttcattacat aatggaaaaa attaaaaagt tggatgttac
    14641 cgatcaatgg attcataatt tacatgaaat cgatacttta ttacttcgat ataatcaatg
    14701 cactattggg gaaggagcag atgtctatcg gaagttaagt agcaaaatgc tgaatataat
    14761 ttctgtgaag acacctgtac aagttgatgt caaactggaa aaagaggtca ctctgccgcg
    14821 acatgtgttg gatgatgctg caataggtgc tgagatcatg tgtagattgt atgcacctcc
    14881 ccaaacttat gaattggcag aatacttgaa tcgttttttg gagaaatacg gtgtgtatca
    14941 ggaggtccca attaatgaat tgtttgatga ggattgggga ctcggaatac cggagatgta
    15001 ccgtacaaat atagagaaaa gttcaatgga ggatgtaggg gcgtttaaac gcaacgctat
    15061 tctttttcaa tgggttgcga atgcaatttc taaccatgaa atagagctta tcctgacaga
    15121 tgagcaggta gaagaactta cagtttttga taattttgaa gcttctcctg aaacgatgga
    15181 gatctattat agtatttatg ctaattcccc tgaaaaggtt gattctggcg attatgcgtt
    15241 gttacttgga gcaagtgctg gttccaatag agcgggtaaa acttttggtc gttttctgga
    15301 tatgtttaat gaggaatttg tccaaaaatt ctctgaagta tatgatcatc accgatgttt
    15361 ccatccagaa gcattgttgt cagagatggt ttttatgcct gaacagggaa aaatatcaaa
    15421 tatatcacta agtaaaaatt taatggaata tgagattgta tctggaacta cctcttctaa
    15481 agacaaggag catacactac acattgatga cttgctggtg ggtgcaactc ttgaccgttt
    15541 ctatgtcaaa tccaaatctt taggtaaaga aataatcccc ttgcaaacac atatgcttaa
    15601 ttataagctt tcaccacata tattcagatt cctaacggat gttaccaata aagaaattgg
    15661 catgtggtcc tattttaact ggggaccatt agagcaatca ccttttttac caagactagt
    15721 gtataaaaag gttattatta gtgctgcaca atggaaactg agcaaggcca cattgaacat
    15781 ttcaaaacta agtgaaccaa aaaaaggaga agagcttttt catacatgga gacaacaatg
    15841 gaatgtgccg cgctatgttt atttaacgat gggtgataat cgtcttttac tagacttgtg
    15901 caatctcttt catgtgaaag aactgcttcg tgagttgagc aagacacgtg atggacaggc
    15961 gcttctactt actgaatgtc tgggtgaccc ttcccacact ccattacatg gggcagcagg
    16021 taaatatatg ggggaatttg tgtttccatt aaagaaaaaa aatataaagg tgaaacctgg
    16081 tatccctagt tcacataata agattgcact ccaaaatttt actacccata ctcctgtcag
    16141 catgaataga gggatatttc caggagggga ttggttatac cttaaattgt acggagtcaa
    16201 ggaaagagag acggacctta ttggtttaag tttgggtcag ctattataca agcccgattt
    16261 tgaggactgg agtgaaaaag cctattttat acggtatgtt gatcctgaac atcatatccg
    16321 tctacgattc cagggagacc ctgataagct gtggacaact ggtttagcgc aattaaatca
    16381 gtgggcagtc caaatgcgtg aagaaggact tataacgaat atgattttgg acacatatct
    16441 tcctgaaata gagagatatg ggggacagac acttatggaa ctggcagaac aagtttttga
    16501 catagacagt aaatgggtcg tctcctactt ggggggagtt cgttctaaat tttttaattt
    16561 ggacgtagag attgcggcgg ttattaatat tattcattat ctgagtggct ttggtttaac
    16621 aattcaacag caagtcgact ggcttgaaga gagaattgac agcaagccgc atatgaaggc
    16681 attcagggat attaaaaaaa cattgatcac ctctgtagaa ccgaactatg aatggattcg
    16741 gcaggcggat atggtctcac agaccgcttt tttggaactt gtagaaaaaa gacaagccag
    16801 cattgagcgg tatgctcaag caataaccct tgctaaaaat aataatgtgc tcactaatca
    16861 tcctaatgat attttgggca gtgtaatcca tatgcacttg aatcgtctgc ttggtgttaa
    16921 tagggagcgg gaaatgaaat gtatggcttt agcaaagcac acactagcta acttgttgca
    16981 ccggaaaggg gtaggccatg tcacagtcta atgggcaaaa aaatgatttg gtgtcattgt
    17041 cttataagaa tatatttcgt acttttttat tttggcctcg tatattcaga ttactatggg
    17101 atactcatcc cgcctttcta attgctatac tcattactaa tttgtttaaa ggtgcgattc
    17161 ctgctgtgat tcttttagct acgagagaat tgatcaacag tgtggtggga ggggtgtcag
    17221 gaggaagctt tcaacctgtt tttattgctt ttggcgtctt aataggcatc aacattgtgt
    17281 atgatttgat aagcatagga gaaagttttt ttcgaaaaat gtttcaaagt caactatcaa
    17341 accaagttaa tatcagactt attgaaaaag cacagaagat gtctttgcag tcgtttgagg
    17401 atgcagatgt ccaaaatatg cttcaacggg ctcagggaga ggcagattac aggccttttg
    17461 aaatttttac tcaaatcctg gccattatta gtagtgttgt aaccttattt tcagtgggcg
    17521 ctattcttat agcgtggaaa tggtgggcgt tcttatttat ttttcttatt ccctgtttat
    17581 cattctattc tttcttacgc atcggacaaa gagaatttaa tgttcatttt caaagggcag
    17641 gaaggcaacg cgaatcctgg tacttgtctt ttttagttac cagagataac agttttaaag
    17701 aagtgaaaat ttttcaattg ggagactatt tgcgaaaaag atataagact atacttgaag
    17761 gattttaccg tgaggataaa gttctagcag ttcgtaggtc atatacttct cttgtatttc
    17821 aaattgtaaa ccagggggca ggtggattta ttattttcat ggcagtacaa gctacttttg
    17881 taggccaaat tttagtaggg aacttggtaa gcttaattca ggctataacg ttaacacagt
    17941 caacatccca gagcatcgta cagggaattt taagcttgtg ccaaaacaat ttatacatta
    18001 agcagctatt cgacttttta gatatgcctg aggaagcgga gacacaaaca ataaatcaga
    18061 gtttgtccgc cattcaaagt attgaatttc gcaatgtttc gtttaggtat ccaaatactg
    18121 aggtaaatgc aatttcaaat gttagcttca ctctttctca aggagagaag ctagccattg
    18181 taggaagaaa tggttcgggt aaatcaacca tcgttaagct gttgactcat ttgtactcag
    18241 aatttgaagg ggaaatttta attaatgggc actctataca tgaaatggat aaagatagct
    18301 tcagagaaaa gataggagtt gtttttcagg attttgtaca ttatgagatg gctgttagag
    18361 ataatatagg ttttggaaat gtgtcttcta gagaaatgga tgaggacatt tggacagcta
    18421 tagacaaagc tggaattaca gatttggtag tcagtctgcc cgataaaatt gataccttgc
    18481 ttggaaaatg gtttgaagac ggacaacagc tatctggagg acagtggcag cgtattgcaa
    18541 tagcaagagc tttcatgagg aacgccgatg tatatgtctt ggatgaacca agctcgtttt
    18601 tggacccaca cgcagagaaa gaggtttttc aaaagtttga tcagcttgta aatgagaaat
    18661 taggagtgtt tatatctcac agattgtcct ctgcacgcat ggcggatacc atcattttaa
    18721 tggaggaggg caaaatcatt gagacaggga gccatgaata cttactggat atgaacgggg
    18781 tatatgctga aatgtttcgg ctacaagcct cgtcgtatct tccacaacga gaatgtgact
    18841 ttcaggagga aaatacgtcg ccctctttag taaggacgac aggtggataa taataaagga
    18901 caaataccct cctgtgttgt aggagggtaa tttctatccc atccacagca gtcgaattac
    18961 agccatactc acaataccga caataacggt agccagcagg tttttgctcc ataaggcagt
    19021 caccagtgta ggaaggatcg caataagtac ttgccaatta aaagtgacgg agccttccgt
    19081 tcggacgagc aaatgttcca tgacgagcgc cgtaaaaatg caaataggga tgtaggacag
    19141 ccattggagc actggtttgg gcagcgccag cttttgcagt acgacgaagg gaatgattct
    19201 cgggatggct gtgacgacca tgccgccgat aatgatgtac atgacgttgg gatcaatgtt
    19261 catttgtcgg ttaacactcc aatcgttgcg gtcatcacag tagctacaat gacggcgata
    19321 tgcgacggca cccaccagga caaaaggtac atcagcacag ccatacacag cacgagcagc
    19381 agacggtgct tgagcttgga gatctggacg ctttgcaact gggaaataag cagagctaga
    19441 aacatagctg gcaaggcaaa atccagacca aatgcctccg gccgggaaat ccagtttccg
    19501 agaatccctc ctgccacaca ggaggcaatc cagacgagat atgcggtgat attaagtccg
    19561 ttcatccagc gatcgcttac ctgcccgcct ttagccaatt tatccgacgc taccccaaag
    19621 gattcgtctg tcaacagtac gccgatgcct atgtttttcc acaatgaata ttttgagaaa
    19681 taaggagcca acgatgcgct taacaacagg tggcgggcat tcacaatgaa tgtcgttaaa
    19741 ataatgacag aggggggact ggacgcagcc agcatcgaac acataataaa ttgggaagct
    19801 cctgcgtaca caagcgctga catcagggca atttccatcg tgcccacacc tgacgaggcc
    19861 cccacaatgc ctgccgcgaa gccaatgcac acataaccga gcaacgtagg gatacaatcc
    19921 ttgactcctt gtaaaaagtg gagtggatcg cgctccgttt cgctcaaccc cgaagctata
    19981 gacatttcaa ccttccctcc attctaaatt tcattatagt atataacgga acctcgaaat
    20041 tgatcaatat attatacaat tgtatgttat gttgaacacc aatttgataa taaaatgtca
    20101 tacatctata tcaaataaaa ggaggtgatg aagcgactga gcaataccac acagtatctg
    20161 ctgttatgaa cgattgaata gtacgatcca gaatgacgaa tctctacata aaaaggtgtc
    20221 caacgacctt aggatcgtcg gacacctttt gctttcttac gcttcaatcc ttgattcacc
    20281 ctgctctacg aatcgcttaa cttcctccat cgacggcaag gctgcaatcg ctccaacttt
    20341 ggtgcatacg atggcgccga cttgattggc aagtgttaca aattcctgct gctgcttcca
    20401 gttggtagta aatgccttag gctgactcag ctggctgatt tgatacagca tagctccgac
    20461 gaaggcatct ccggcaccgg tagagtcgat cgatttgaca gcaatactgc cgattagcga
    20521 acgggagaca ccgcttgaga tgagtgttcc ctctttcccc aaggtaactg ccaccgtctt
    20581 ggctcccaac ccatgcaaaa gatccaatga agcattgcgg tcagccagcc ctgtaatgat
    20641 gtttaattcc tcttcgctta cctttaccaa atccgcattg tgtattcctc ttctggacag
    20701 tgcgataaat tcctccagcc tgtctttcca gaggtccccc cggtaattgg gatcaaagga
    20761 ggtgaattgc ccattggcct tcgcctcgtc caataaagat aaatacgctt cctggaaagg
    20821 atcggcgagc aaggccgttg ccgagccaaa atgcagaatg gcagcctgcc gagtccattc
    20881 tctatcaatg tcctgcagag acagctgacg gtcagctcca cggttgaaca cgaaatcccg
    20941 ttcgccgtta gcggcaaggg aaacaaaggc cagtgtagtc ggcgttgccg gatcaaaaag
    21001 gagcatggac gtatccacgt gctgctcatc cagagtttgt ttcaggtaca tgccgaacgg
    21061 atcggctccg acttttccca agaatgacgc ttttcctccg agcttggcta cggctgcgct
    21121 cacatttgcg ggagcaccgc cggcctgctt ggagaaatgc tgacccttgg caagattgac
    21181 atcaatatcc gtgcagaaaa aatcaatgag cagctcgccc acacatagaa ccgttccgac
    21241 atttttcact ttgattcacc tcttggcaga tttagtttaa aacaggcgtt gaatctcggt
    21301 atacaatatc tgttgcaaca tgggtcactc ggtacggcat ggtattatct ttgattctgg
    21361 acaataacat ttcggctgaa ataataccca tctgactact gtaaatatgt acggtagtca
    21421 gatgtggctc gactacccgg gattctgaag catcatcgaa cccgcagaca gcaacatctt
    21481 ccgggacttt aatccccttg tttttcaaag attttatcac gctgatggca atgaaatcat
    21541 tggcgcaaat aaagatggag gggcactccc tcagggcatc caattgctgc tccatccagt
    21601 tctcctctat aaagaaattg cggtccggcg ctacaatgct atgggcaggg tccaaggtga
    21661 tttcggcttc tgccagggcc ttattgaatc ccgtccagcg ttcattgaag cttttgcagt
    21721 gattgtaatc gcctacaaaa ccgaagcttt catagccatg atctattaat ttccgggtaa
    21781 gacagtatgt gctatgctca ttttccatta ataccagatc tgccttcaat tccggataca
    21841 ccatatctgc agcgcaatca ataaaaatgg ttgggatgcc aagatccgtg atcagcttgc
    21901 tgtattcctt gctgaacatt tcgatgcaga aaatgccagc cacattcgaa ggttcgaaat
    21961 taccgggtag ggtcatcgta ttgatatcgt tctcacggac aaaataaatg gataaagtat
    22021 agccctggtt gctgatttcc ttctccagcc cgctgatcag cagtgatcca aagtgtgagc
    22081 tattgggaag attacaggtc aaaagtgcga tattgccctg tttttcagag gctgtttcca
    22141 tataagaaaa ttgtttgtat ttaagctcca ctgctttttt gatcaccttg tccctcgtta
    22201 cggcaggaat attctctact ccattaagcg ccttggatgc agtgtttctg gaaattccca
    22261 aggcatcagc gatgtcttga atagtaacct ttgactttct cgtcatattg ttccacctta
    22321 ttcttccgaa ttaagattct tcatatttct aaatatatag tattttcatg cttttaacaa
    22381 tgaaattatt caaatgaaca aaattagttt acatttactc attaataggg tgcattttta
    22441 agtatttttt gcttaaaata ttacattcct ctttaatcat gcatttttaa tgaatttagt
    22501 tgccgaaatg tattgactta ttcaattctc acctgttaaa ttgtaagaga aaaaatgttc
    22561 aaatgtaaaa tgtaaaccca ttcatcttgg gggaatgtaa atttctagtc atgttggagg
    22621 tgggggaatt accagtaggg catttgcaaa gcatcttgcg taattatgtc agagagatga
    22681 cataacatgg cttataactg tctttaataa caagccgtga acagtagggg ggaaaaagat
    22741 tggcaaactc gatcgctcaa aaaaggggag ttaaggcttc agaaacaaaa aaaagaaacc
    22801 attggctaag ttacatggtt cgaaattata tattgtattt gtttctggtt ccgtccataa
    22861 ttcttaccgt cattttcaag tatgttccca tgtacggctc aatcattgcg tttaaaaatt
    22921 tcagtccaag aaaaggcatc atgggcagcg aatgggttgg atttgaacat tttcagcggt
    22981 ttctttcatc accgaatttt tatgacattt taatgaatac gcttaaatta agcgcttacg
    23041 gtcttattct cggtttccca gtaccgatca ttctggcctt aatgctaaat ctgatcagag
    23101 gagcgaagct caagaagaat attcagctta ttgtttacgc acctaacttc atctcggttg
    23161 ttgttgttgc cggtatgctg tttgtttttc tatcgccggc tggaatagtg aacgctttgg
    23221 taacaacctt caccggcaag ccgatttctt ttatgactga tcccgcctat ttccgaacgg
    23281 tatatatttt gtccggtata tggcaaacag cgggctggtc ctctatcatt tatgtggcca
    23341 ccttagccaa tgtggacccg cagttgcatg acgctgcaac aattgatggc gcttcattga
    23401 tgaagagaat cttccacatt gatctgccag ctctcaaacc tgtcatggcg gtcctgttca
    23461 ttctcgctgc aggaggcatc atgtcgatcg gctatgaaaa ggcttacctg atgcagacgg
    23521 ctctgaacac gccaacctcg gaaatcatcg caacttatgt atacaaggtg gggttgcaat
    23581 ctggcgatta tgcttattct acggcaatcg ggttgttcaa ttccgtgatt aatgtggtcc
    23641 tgctgatttt cgtaaatacc gtcgtcaaga agctgaacga aggggaaggg ctgtattaaa
    23701 gaaggaggta tttatggata ttcattacac cgggaaggac cggattctga tcatcatcaa
    23761 ttatattctg cttggtttgt ttgttctcgc tattctgtta ccgctggtct atgtggtgct
    23821 ttcgtccttt ttgactccaa ataccctgat taccaaaggg tttgccatta catcatcaga
    23881 ctggacactc acgggatatg ccaaaatcct aagcaacagt gccatgatcc gcggtttttt
    23941 taatgctatt ttttattcag cagcctttgc gttcgcaacc gtattatttt ccgtcttcgc
    24001 ggcttatccg cttgcgattg aagagttggt agggaaacgg cccattatga tctttttcct
    24061 gataacgatg tttttcggtg gcggtctgat tcctacctat ctggtgatta aggatttagg
    24121 catgttgaat acggtctggg ccattattct gcccggctcg atcagcgtat tcaatattat
    24181 tctggcaaag acttatttcc agggacttcc gaaagagctg ttccaggcgg cgagtataga
    24241 cggagcttcc gagctcagta ttttctttaa aatcgtcctg ccgctttcga agcctattat
    24301 ttttgtttta gctttatacg cttttgtcgg acagtggaat tcttattttg acgccatgat
    24361 ttatctggat gatccgaagc tgtttccgct tcaactggtg ctgcgctcca ttttgataca
    24421 gaatcaggtt cagcccggca tgattgcaga tgcgatggca caagcggagc ttaagaaatt
    24481 gtctgaaatg attaagtact ctgccattgt catatcaagt ttgccgttga ttgtcatgta
    24541 tccattcttc cagaagtatt tcgaaaaggg tgtcatggta ggttcgatca aataacaaac
    24601 cgggggaata gagatgaaaa aaacattact aaccttgtct gtgctggtgc tttctacttc
    24661 gctgcttgcc ggatgtggcg gttcaggcaa taattctgcg gcatccgaag attacaagct
    24721 ggaaaatgtc actctgccgc tcaaagagaa agttaccttg cattttatga ctcaaagctc
    24781 gccgctggca ccttccgatc ctaatgaaaa gatgatttat aaaagactgg aagaaaaaac
    24841 aggggtgcat atcgatttta ccaacttcac ctccgattcc ttcattgaaa aaagaaacct
    24901 ggctgttgcc agtggagatc ttccagatgc catactggat gccggctatt ccgattacga
    24961 tttgttgaac ctcggaaagg atggaactat tatccctctt gaggatttga ttgataaata
    25021 tatgccgaat ctgcagaagg tattgaagga agcacctgag tacaaatcca tgataaccgc
    25081 acaggacggg catatttatg cttttccctg gattgaggag ctgggggccg ggaaggagag
    25141 cattcattct gtaaacgaca tgccttggat caatgtggag tggctaaaaa agctgggact
    25201 taaaatgcca aaaacgactg aggatttaaa aaatgttctg ctcgcattta aaaatggcga
    25261 ccctaacgga aatggccaag cggatgaaat cccgctgtcc tttatgctca ataacggcaa
    25321 tgaggacctg aattttctgt tcggttcatt tggtcttggg gacaatggcg atcatacggt
    25381 agtgaccaat gaggggaaag tggtcttcac tgccgatcag gacggctata aagaggggat
    25441 caaatatctt aatgagctgt ataagctgaa cctgatcgac gaagagtcat tcgagcagga
    25501 ttacaatacg tatctggcca aaggccagaa tgaaaaatac ggtctctact ttcaatggga
    25561 taaggcgaat atttcgggag acaacgataa gtatgaattg atgaacccac tcgcagggcc
    25621 aagcggtaaa gtcaatgtga cccgcacgaa caatctcggc tttgaccggg ggagaatggt
    25681 gattaccagt gacaacaaaa atcttgagct tacggcaaaa tggattgacc agctgtatga
    25741 tcccattcag tccgtacagg acaactgggg cacctacggc gacaaaactc agcagaacat
    25801 ttttgaatac gatgaagcga gtcatatgct gaagcatctt ccgcttaagg gaacggctcc
    25861 tgtcgaactg cggcaaaaaa cgaatatcgg tggtccattg gcaattcttg acgagtatta
    25921 cggaaaagta acgaccaagc ccgacgatgc agtaggccga ctcaagctca tgaaagaaag
    25981 actcgttcct tttatgaagg ctgaccacaa tttcccgaaa gtcttcttct cgctggaaga
    26041 tcagaagcag atctcaacct tggaaacaga cttatttgcc tacgttaacc gcaaacgggc
    26101 ggaatggatc aaaacaggca aagtggaaga agaatgggcg gaatataagg ccgagctttc
    26161 cagacttgga ttggacaaat ggctggaaat caaacagaaa ggctatgaca gatatcttaa
    26221 agatcaaggc tgaaacatat aaaaggtggt tggggctgtt aaacacctta tcaacaatca
    26281 ataggagagt ggataccatt aaagacatgc acctaacgaa tgacaatagc aggagcagaa
    26341 aaggattacg aaacagtaat tacagggagg catacaggcc tcaatttcat tattcaccgg
    26401 agaaaaattg gatgaacgat cccaacggct tggtttacta tgaaggagag taccacctgt
    26461 tctaccagca tacgccccat gatacgcagc ctgactttgg ccgcatgcat tgggggcatg
    26521 cggtaagcaa ggatctagtt cattgggacg aacttccacc ggcaattccg cctggagagg
    26581 acggagcgat cttctcggga agtgcggtgg tggataagaa caatacaagc ggatttttca
    26641 acgaagaagg atcaggattg gttgccattt atacgaatga gggcaacagg gctcagcctg
    26701 gcaagccaca ggtgcaaagc attgcttaca gcaaggacaa gggtcgaacc tggacaaaat
    26761 atgaaggtaa cccggtttta ttcccaacgg aaacgctaga ctttcgtgat ccgaaggtgt
    26821 tttggcatga tgaatcgtcg atgtggataa tggtccttgc tgtaagagac cgtgtagaat
    26881 tttacacatc tccaaacctt aaagaatggt cttttgcaag cgaattcggt tccgacattc
    26941 cgggtatcca ccggggaatt tttgaatgtc ctgatgtatt tcgaatccaa gtggatgagg
    27001 accctaatac c
//
