LOCUS       NZ_PNXQ01000012        23987 bp    DNA     linear   CON 30-JUN-2024
DEFINITION  Paenibacillus terrae strain PIC167 Contig_012, whole genome shotgun
            sequence.
ACCESSION   NZ_PNXQ01000012
VERSION     NZ_PNXQ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus terrae
  ORGANISM  Paenibacillus terrae
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 829445)
  AUTHORS   Gomez-Lama,C., Legarda,G., Ruano-Rosa,D., Pizarro-Tobias,P.,
            Valverde-Corredor,A., Niqui,J.L., Trivino,J.C., Roca,A. and
            Mercado-Blanco,J.
  TITLE     Bacillales members from the olive rhizosphere are effective
            biological control agents against Verticillium dahliae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 829445)
  AUTHORS   Gomez-Lama,C., Legarda,G., Trivino,J.C. and Mercado-Blanco,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JAN-2018) Proteccion de cultivos, Instituto de
            Agricultura Sostenible, Av. Menendez Pidal sn, Cordoba, Andalucia
            14004, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2017
            Assembly Method                   :: Megahit v. 1.0.3-29-g707d683
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_000235585.1
            Genome Coverage                   :: 130.81x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005217525.1-RS_2024_06_30
            Annotation Date                   :: 06/30/2024 04:15:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,015
            CDSs (total)                      :: 4,939
            Genes (coding)                    :: 4,759
            CDSs (with protein)               :: 4,759
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 180
            CDSs (without protein)            :: 180
            Pseudo Genes (ambiguous residues) :: 0 of 180
            Pseudo Genes (frameshifted)       :: 50 of 180
            Pseudo Genes (incomplete)         :: 143 of 180
            Pseudo Genes (internal stop)      :: 19 of 180
            Pseudo Genes (multiple problems)  :: 28 of 180
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:51:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 456378
            Orig. end                         :: >480365
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PNXQ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>23987
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..>23987
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>23987
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:>13987](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..>13987
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            274..1194
                     /locus_tag="C1I60_RS12130"
                     /old_locus_tag="C1I60_12150"
     CDS             274..1194
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="C1I60_RS12130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137061937.1"
                     /transl_table=11
                     /translation="MQQATGQLPVIRMEGVSKIISSKAIVDDLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSIKTDFEKAVSHIGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTKERIDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLSRSEGITVFVSSHLLSEMELMCDRVAIIQNGRLIDIKQ
                     LKSTVEEAQTAEIAFEVNDAQHAYALAGAGRVEGNQLLLHLEREQIAEMNSLLAANGVK
                     VYAIRPVARTLEDQFLEVTGGGSIG"
     gene            1187..1969
                     /locus_tag="C1I60_RS12135"
                     /old_locus_tag="C1I60_12155"
     CDS             1187..1969
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="C1I60_RS12135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12155"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_137061938.1"
                     /transl_table=11
                     /translation="MADFFRLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLIALVSDQ
                     VSVWDGIVLTAMFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTFILVAMVTLSSWLMLSKDAPAGSIPPFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTIYNSIGLFSTDRYEWTKYVLFTHMDLKKYLDM
                     PPGTVSSGLTFSLTVLATYYVVFIAITWVVFVKRDVST"
     gene            2228..3313
                     /locus_tag="C1I60_RS12140"
                     /old_locus_tag="C1I60_12160"
     CDS             2228..3313
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="C1I60_RS12140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12160"
                     /product="AI-2E family transporter"
                     /protein_id="WP_137061939.1"
                     /transl_table=11
                     /translation="MLPNNRFFRLTTGIVMLLLIIYLGTKVSFIFSPIVSLVSLLVVPL
                     MLSFFFYYLLRPVVDLMERRKIKRPISILLIYLVIAALLFIFSWGVWPTLRDQVTNLFE
                     NAPKLISSLVDQLSQWRHNQSLRQVLPPGEDPLSRLSDTLNEAFSALSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGRKFGPKMLNFFPKEYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGIMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAI
                     WSLVVVIAAQQIQDNWLSPVVFGKQLDIHPLTVVILLLVGGDLLGILGIVLVIPLYMCA
                     KIVIRKVYHLFLEHRVEDMME"
     gene            complement(3320..3784)
                     /locus_tag="C1I60_RS12145"
                     /old_locus_tag="C1I60_12165"
     CDS             complement(3320..3784)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="C1I60_RS12145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12165"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_137061940.1"
                     /transl_table=11
                     /translation="MFKDSKKKLSAPVTDTLLANGTSFEGTIEAEANIRIDGHFQGDIC
                     STHAVVIGESAVVRSDIIARDVTLAGKVFGSITTEGRLTITPTGELYGKVAAAALVISE
                     GGVLDGTSQMIRTKDAEPSAVSTDASDLETQSGTRKDRENRQATLQSETG"
     gene            complement(3828..4859)
                     /locus_tag="C1I60_RS12150"
                     /old_locus_tag="C1I60_12170"
     CDS             complement(3828..4859)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="C1I60_RS12150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12170"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_170970787.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQYSTAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMDVTVADKDAAIGRLRREVMELTNQATSIRERL
                     QRVTELEQQMQQFIRKYGKSSATSSSKTVVTPLSWDASGYTGGELITVHENTAMLTRQA
                     KDDFQEIESMLDTVERTVPRSIQQANAVQQNLEQKQAAQLLQTRRLALAEQGKPSAWPV
                     SSRQMTSSFGYRSDPFTGKSAFHSGMDIAGQTGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGFQSWYMHLSGMQVTPGERVRKGQTIGLLGSTGRSTGPHLHFQIVKHSQPVDPLL
                     YVQ"
     gene            4988..6418
                     /gene="cls"
                     /locus_tag="C1I60_RS12155"
                     /old_locus_tag="C1I60_12175"
     CDS             4988..6418
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="C1I60_RS12155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12175"
                     /product="cardiolipin synthase"
                     /protein_id="WP_137061941.1"
                     /transl_table=11
                     /translation="MLWLLLVLIVFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYKKRKMVRKGGSQLFREFRERLWSQSRVIENVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTDGEETFEAMLTALEQAQSHIHVEFYIFRADDIGTRFQEVMIR
                     KAREGVKVRFVVDGVGSYNLPYSFIHACNEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGLIGFVGGINVGDDYLGKYPKVGFWRDTHLQMEGDSVYFLQNAFLSDWKLASGERL
                     MDENLFPPHTCEGEEEVQILSSGPDQVWDTIQEMCFGALAVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGVDVRIIIPYKSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKIII
                     VDDLLGSVGTANMDMRSFFYNFELTAVLFARSALEHLSADFEEDLSNSSHIDLKVFRRR
                     PRLQKTAEILARMLSPLL"
     misc_feature    6575..6591
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 21.83"
                     /tool="antismash"
     gene            6614..7558
                     /locus_tag="C1I60_RS12160"
                     /old_locus_tag="C1I60_12180"
     CDS             6614..7558
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="C1I60_RS12160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12180"
                     /product="YitT family protein"
                     /protein_id="WP_137061942.1"
                     /transl_table=11
                     /translation="MSVVSKEVQSLSEITDVTGELTKISKIPANPKNKAKRLFQRAAMI
                     IFGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLVIGYKQI
                     GKTFALSTLFGIIVMSIGTTLLHSVNALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISEKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKNIVEDWDPHAFVAIGNIHDVKGGRFKKKGIH"
     gene            complement(7613..8503)
                     /gene="ligD"
                     /locus_tag="C1I60_RS12165"
                     /old_locus_tag="C1I60_12185"
     CDS             complement(7613..8503)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="C1I60_RS12165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12185"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_137061943.1"
                     /transl_table=11
                     /translation="MGQAVKGIITIEGLEIPITNPDKPLWPEAGITKALYLRKLAVLAP
                     FLLKYSHNRLLTVIRWPHGIHGDFFYQKNAPQPRPGYIETFLHDGIEYMVLGTLPQLLW
                     LGNQAALEFHPSLHQAGSTLPCEWMIDLDPSREVEPRIMEAAFIVGEVLASLGLESVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWDEVRQDVSPLDYHLLNIEERLNQVGDLISKV
                     PPQPIEDVLKHMRAT"
     misc_feature    8671..8684
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.44"
                     /tool="antismash"
     gene            8736..10004
                     /locus_tag="C1I60_RS12170"
                     /old_locus_tag="C1I60_12190"
     CDS             8736..10004
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280289.1"
                     /locus_tag="C1I60_RS12170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12190"
                     /product="sulfotransferase"
                     /protein_id="WP_137061944.1"
                     /transl_table=11
                     /translation="MIDKQGEGLVFLLSVPRSGSSLVTTILQNHSRLFATQEMWFLLSL
                     HDLPQSQTRPYGGTGIIRQFFNGMVPPHVLEQASRSYALEIYNGLLEGTNANMVIDKSP
                     RYYTVLEFIDRLFPAARRVWLIRNPLSIAASFKKVNQMRGERFHLLEELESPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLVYEQLVANPAVEVGRLCDFLGVDYEPGMEKYGDFAD
                     TPKSSLFYSMGAGDPFVGEHEQTHQDSVHSWQHLLNKKEIELYCRSIGARMFTQLGYGE
                     ALEQAEHITRVRFEEEADVELLSRRTSQFLQQSGFEWKNAYRMLEKQGADNRGFIIKAG
                     QHPVLQDSRQNDAVQVVNDRRLQSLENRLAHSYEERNRLIAQLQTYQRRNQRLRSRIPF
                     ARHLGRWASVALSVMEKEKGGKT"
     gene            10001..11926
                     /locus_tag="C1I60_RS12175"
                     /old_locus_tag="C1I60_12195"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="C1I60_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12195"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_137061945.1"
                     /sec_met_domain="GATase_7 (E-value: 6.5e-19, bitscore:
                     63.7, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.9e-26, bitscore:
                     87.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYSFGHKPVCTEEGGKMMQALRKYPADRVCAWCEGSIFL
                     GCHAQHVTPESIHERLPFYDEERNLAITADAIIDNRSELFERLGVGQERRQDITDSELI
                     LLAYDKWALDAARYLIGDFAFVIWDAGLHRLYGARDMAGSRTLYTYEHDRGFAFSTVVA
                     PLLTLPSLRKELHEPWLAEFLSIRAMQESVDIGTTGYKHINQLPPAHWFTMEEGKSTIH
                     KYASLDDVEPLRLKTGGEYVEAFREVFSQAVNARLRTHRGVGAALSGGLDSGAVASFAA
                     PSLRLQQKPLHAYSYVPVQDFTDWTPSTLLANERAYIQSTARYVGNIHENYLDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEQNVGVLLTGARGNFTISWGPALDYYA
                     RQLRRLHWLQSFQGLWQYSKLTGRRVSHLLPVMLKKATSLDSRSWLRGGNRSPVPSLIH
                     PEFAKRMNVEDIPTLSGTGWMKNADQARKEKFTNLAIANKNGVVATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRGAMRDYLPDDVRLNQRVRGVQPADWLHRML
                     PCWETFMGELQLLCHDLHAAEFLNIDVIKTAMAKFRQPRPEQASDPNLRLLMHSLIVYR
                     FIRGFN"
     gene            11981..12109
                     /locus_tag="C1I60_RS12180"
     CDS             11981..12109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="C1I60_RS12180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_137061946.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEALDINQTMAGKGWKQIDWVSDHDADLYNPS"
     gene            12219..13280
                     /locus_tag="C1I60_RS12185"
                     /old_locus_tag="C1I60_12200"
     CDS             12219..13280
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280291.1"
                     /locus_tag="C1I60_RS12185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12200"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_137061947.1"
                     /transl_table=11
                     /translation="MHDRSTNVNLTMYTAFGLKLASELYLPELIPAAPGAVEDVVIRQT
                     DLTAWSDQLEQANFVMQGERFMFYIPDTAIYAVRRGREIEVCSYSGADPDTVRLFVLGT
                     CMGVLLMQRGIVPIHGSAVVIRGRAYAFVGESGAGKSTLAAAFTQAGYRIVSDDVIAMQ
                     ATASKTIVYPAYPQQKLGLESLLQLEALQGNRHAHKSNHGLVLMDGNPAMLKYGHLRKL
                     TGELNKYAVPRVDYFYNKPLPLGGVFELVAESPNREFQCEGKLPAVMEQPLNMLECLHT
                     LLLHTYRRVIIPRMSLGEWHFGTVAQVARQVEGWRLLRDSSAFTASEVVHRVLDIICKE
                     ENSCGSYSFHEGS"
     gene            13249..13551
                     /locus_tag="C1I60_RS12190"
                     /old_locus_tag="C1I60_12205"
     CDS             13249..13551
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349786.1"
                     /locus_tag="C1I60_RS12190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12205"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_014280292.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.7e-25,
                     bitscore: 84.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.2e-17, bitscore: 59.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAATHSMKDHDRVIHGEEVYVSDMDGEKVMMSINTGKYYNLGFTG
                     GRIWELAESCPSLGEIVAALTDEYEVDEERCRQQVHTFVAELEREGLLKLLRETV"
     aSDomain        13285..13530
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1I60_RS12190_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="6.10E-27"
                     /identifier="RREFam002.1"
                     /label="C1I60_RS12190"
                     /locus_tag="C1I60_RS12190"
                     /protein_end="94"
                     /protein_start="12"
                     /score="84.5"
                     /tool="antismash"
                     /translation="VIHGEEVYVSDMDGEKVMMSINTGKYYNLGFTGGRIWELAESCPS
                     LGEIVAALTDEYEVDEERCRQQVHTFVAELEREGLLK"
     gene            13553..>13987
                     /locus_tag="C1I60_RS26310"
                     /old_locus_tag="C1I60_12210"
                     /pseudo=""
     CDS             13553..>13987
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="C1I60_RS26310"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12210"
                     /product="lasso peptide biosynthesis B2 protein"
                     /pseudo=""
                     /sec_met_domain="PF13471 (E-value: 7.8e-26, bitscore: 86.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWIQRLRRLSPEIRRLLPEAWLQLGWARLHQHRPFEDYARGWGIR
                     MEETSWECDARQKQDVRHISHAVELASRYTPWHSSCLVQAVAAMTLLGRRKLDCTLYLG
                     TAKNAAGRLAAHAWVRSGPIYVTGEREMGAFTVVGTFGRRA"
     gene            14021..15205
                     /locus_tag="C1I60_RS12200"
                     /old_locus_tag="C1I60_12215"
     CDS             14021..15205
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="C1I60_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12215"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_137062261.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1e-78, bitscore:
                     259.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHTALKSDRWNEDQELTLLLFLLRKDATSRLDTIDAGDLHGLD
                     WARLLRLAEHHRVVPAVYLRLKRINHPAIPAEMLRNLQAQYHRNTLRMLHLQAEAGRVT
                     GLLMNHGIRVLMLKGPALAQQLYGDVSLRTSKDVDLLIAPGDMDMAEQWMQEAGYVPKS
                     GEARVLGSWKWKDHHASFLHPHKRVEIELHWRLHPDAGGEPSFEDLWKHRQTDEVTATG
                     VPCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVRAVDWEALLPMMRRYGGLPA
                     GGQAWALAAALLGTSIPEPLRQVAATRLAHRLALSALDFIQASDPVAEPTIQQPTSRSY
                     LLSLKEPSHRLLYLISRLLPSTGDPAVLPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15226..17100
                     /locus_tag="C1I60_RS12205"
                     /old_locus_tag="C1I60_12220"
     CDS             15226..17100
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="C1I60_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12220"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137061948.1"
                     /transl_table=11
                     /translation="MYHLRLYMTKLYAVNGGALFLNIGCMIIVSLLEGLGIYMLVPMLA
                     AIGIFGGHAGMAILSGGLDHFLSNIPKSWLLPGMLLLFALLLIGQALLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWTFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVIF
                     TLIQIALAFWLSPSLTGLVFLCGLGLFVVFRRSIQNAKQLGDRTTELSQVYFAGITDHM
                     NGMKDIKSNLLEAANIDWFRSLTQRMEDNTTQFVRQNATTQFFHRTAAAVFVACIMFVS
                     LQWLHVSPEKLIVLILIFSRLWPRFALIQASLEYIMSMLSAFESVTKVQQECEAFSDPS
                     LTALTTFETRVSSVLSATHQSVLASTTSSVRQPLYLRTGIECSGLDYRYEGTAALALHQ
                     INLFIPARGMTAIVGKSGAGKSTMVDVLMGFLRPTQGQIKIDGHILDDELLPQWRQSFG
                     YVSQDPFLFHATVRENLKLADADASEQQLWEALHFAAADGFVARLPEGLDTVIGDRGIR
                     LSGGERQRLVLARAVLHRPPVLILDEATSALDGEHEADIQAALERMKGQMTLIVIAHRL
                     STIRHADQIVVLEQGEIIQQGNYRQLVQEERGAFSQLLSYQSSVFSTP"
     gene            complement(17154..18068)
                     /locus_tag="C1I60_RS12210"
                     /old_locus_tag="C1I60_12225"
     CDS             complement(17154..18068)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="C1I60_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12225"
                     /product="Ku protein"
                     /protein_id="WP_137061949.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQISGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPVSQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEIRIAPSQPQANVVDLMAALQASIEAVKPVVTDPGPDVKKRPARKAAATTTQQA
                     VAGDAVSPTPIKKKRSTAKHKET"
     misc_feature    complement(18343..18356)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.9"
                     /tool="antismash"
     gene            18433..18831
                     /locus_tag="C1I60_RS12215"
                     /old_locus_tag="C1I60_12230"
     CDS             18433..18831
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243656.1"
                     /locus_tag="C1I60_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12230"
                     /product="RidA family protein"
                     /protein_id="WP_137061950.1"
                     /transl_table=11
                     /translation="MKNEKITRKNPAGMPKPVGNYTHITKIPRNSELFVTSGQIGVDQN
                     GQFPESFNLQISNTFNNIKSVLDAEQLTADNIIKVNVWATEQIDWDYMYSQWEKLFGND
                     YPAMTIGYLTALGLPEIKIEIEIWAAKA"
     gene            18992..19231
                     /locus_tag="C1I60_RS12220"
                     /old_locus_tag="C1I60_12235"
     CDS             18992..19231
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="C1I60_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12235"
                     /product="hypothetical protein"
                     /protein_id="WP_014280296.1"
                     /transl_table=11
                     /translation="MPGKSYPRQIRHRVGQSHIAFRGPAGGEQDALPPEFALSHGIQPP
                     FPVAVGHVDLEAVVSTSPSHSIPSLDVERIIDED"
     gene            19289..19468
                     /locus_tag="C1I60_RS12225"
                     /old_locus_tag="C1I60_12240"
     CDS             19289..19468
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="C1I60_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12240"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_044645186.1"
                     /transl_table=11
                     /translation="MNVERAKAIYNSSENIAVQLEGKPIWIEHVDEANGMATVQVGSNP
                     GNTQTVRVDRLEER"
     gene            complement(19628..20284)
                     /locus_tag="C1I60_RS12230"
                     /old_locus_tag="C1I60_12245"
     CDS             complement(19628..20284)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="C1I60_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12245"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_137061951.1"
                     /transl_table=11
                     /translation="MNNRELIVRRIAQEFKDGEVVNLGVGMPTMVVDYIPENIHIMLQA
                     ENGILGVGPKAAQGKERLDCIDSGGNYVTSVKGASFFDSALSFSIIRGGHVDITVLGAL
                     EVDEKGNLASWMIPGKKVPGMGGAMDLVVGAKRVIIAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKAVIDVIPGKGLMLKEIAPGLSVEDVQMATEAKLMVSPHLKAIAV"
     gene            complement(20281..20946)
                     /locus_tag="C1I60_RS12235"
                     /old_locus_tag="C1I60_12250"
     CDS             complement(20281..20946)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429861.1"
                     /locus_tag="C1I60_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12250"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_137061952.1"
                     /transl_table=11
                     /translation="MNNKVISAEEAVKKVKDGDTVMVGGFLAGGFPEDLVRALVDTNSA
                     SNLTIISNDTGTPELSIYNLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGVLTPVGVGTMVEEGKKKIEIDEREYLLELPLKADVALIRAHKADEE
                     GNLVINGSSRNFNLVMATAAEYVVAQADEYVKAGEIDPNHVNVPSIFVDAIVKVGGHA"
     gene            complement(20988..21728)
                     /locus_tag="C1I60_RS12240"
                     /old_locus_tag="C1I60_12255"
     CDS             complement(20988..21728)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="C1I60_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12255"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_137061953.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTFQGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEDTETLTGTLHYNHVLVAMGTMPFKYNILDEQETAKAI
                     AKTQVNLKLIPDIDGTPKIAQLVAYNLENITVKGAWSGPARLSLIPHVNAPVADLPVQA
                     YVGGKHFIADLTLPYGRVLYDYLQ"
     gene            complement(21788..22972)
                     /locus_tag="C1I60_RS12245"
                     /old_locus_tag="C1I60_12260"
     CDS             complement(21788..22972)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="C1I60_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_12260"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_137061954.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-05, bitscore:
                     20.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVALVSPLRTAVGSFNKTLAPLSAPELGATVMTACLQQSKLEP
                     ALIDQIYLGNVLQAGNGQNPARQAALKAGIPIDVPESTINTVCGSGLHAVGLAYNSILA
                     EQGNIVLAGGMESMSNAPYLLRNARNGYKLGNGELVDSLVTDGLTCPINHYHMGITAEN
                     VADKYGISRLEQDEFAYQSQIKAVEAKNNKVFEEQIVPVMIKTKKETIYFTEDEHIRGN
                     TTKEKLSHLKTAFKENGTVTAGNSSGINDGAAAMLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISTLLKQQGLSIDDIDLFEINEAFAAQAVAVMKELGANPEKVNVN
                     GGAIAIGHPVGASGARILVTLVHEMARRSSRYGIASLCIGTGMGIAMLVENALI"
     misc_feature    complement(22964..22977)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.1"
                     /tool="antismash"
     misc_feature    complement(22966..22979)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.0"
                     /tool="antismash"
     misc_feature    23295..23309
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     misc_feature    23302..23316
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     misc_feature    complement(23327..23340)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.68"
                     /tool="antismash"
ORIGIN
        1 attcgcacag agcagagtgg agacgagctg gggaaggttt accgtattac ggttacccag
       61 cattataaga cccggtttgg tcattttgat atcgtacagc cttgttatat gacgcaggaa
      121 ggtgaagagt ggcgggtgct ttggatatac aaggataagg aataatagga cgcggtgttt
      181 ctaacaggtt aaatatggta caatacttcc aaaaccggaa atgaacagca aaatagaata
      241 gagcttcact ccggatggaa ggagtttcat agcatgcagc aagcgacagg acagcttccc
      301 gtcatacgta tggagggagt gagtaaaatc atttcctcaa aagcgattgt ggacgatctg
      361 acgctggagg ttccagcggg gcaggtattt ggtttcctcg gaccgaacgg tgcgggaaaa
      421 acaaccacca tccgtatgat ggttggcctg atatcgatca gcaagggcga tatccatatt
      481 tgtggagaca gcatcaaaac cgattttgaa aaggcagttt cccacatcgg tgcgattgtg
      541 gagaaccccg aaatgtacaa gtttctgacc ggctatcaaa atttgcagca ttttgcgaga
      601 atgtcaccgg gggtgacgaa ggagcgcata gatgaagcga tccgcctggt aggactcgga
      661 aaccggattc acgataaagt caaaacctac tcgctcggaa tgcggcagag actcggggta
      721 gcacaggcga tcttgcatcg gccgaagctg cttgtactgg acgagccgac caacggatta
      781 gacccgcagg gtatccgcga attgcgggat tatttgcggc agttgagccg gagcgaggga
      841 attacagtat tcgtatcgag tcacttgttg tccgaaatgg agctgatgtg cgaccgtgtc
      901 gctattatcc aaaacggacg attgattgac atcaagcaat tgaagagcac agttgaagag
      961 gcccagacgg cggaaattgc ttttgaagtg aacgatgccc agcatgctta tgcgcttgcc
     1021 ggtgcagggc gcgtcgaagg caaccaactg ctgctgcatc tggagcggga gcaaatagca
     1081 gagatgaaca gtcttctggc tgcaaatgga gtcaaggtat atgcgattcg cccggtggcc
     1141 cgtacgctgg aagatcaatt tttggaagtg acgggaggcg ggtccattgg ctgacttctt
     1201 taggctggta cataacgaaa atcttaaaat ttacctgcgt gtacggacat ggattatgct
     1261 agggctgctt gcggtcatta cggctgtgat tccgatgctg attgctcttg tttccgatca
     1321 ggtcagcgtg tgggatggta tcgtgttgac ggcgatgttt acatttttcc tcaatacgac
     1381 gtttacggtc attgtagcgg ctgattcggt ggcaggtgaa tttacatggg gaaccatcaa
     1441 gctgctgctt atccgccctt ggacccgtag caaaattctg ttgtccaaat atatatcggt
     1501 cattctgttc agtctgctcg gaacgttcat tttagtagcg atggttacgc tgtcctcctg
     1561 gttgatgtta tccaaagatg cgccagctgg ttcgattcca ccgttcagtg atccgatatc
     1621 ttatgtaacg ctgaatttct tgtacagtta tattgcttta ttcgtgacta tggcctttgc
     1681 ttttatgctg tctgcagttt ttcgttccag cgccttggcg atcggcttat ctctgttcat
     1741 gatgttcacc aaaacaatct acaattcaat cggtttgttt agtacagatc gttatgaatg
     1801 gaccaaatac gtcctattta cgcatatgga cctgaaaaaa tatctcgata tgccgccggg
     1861 tacagtaagc tctggtttga ccttttcgct caccgtgctg gccacctatt atgtagtttt
     1921 tattgcaatt acctgggtgg tttttgtgaa aagagatgtt tcaacctaaa cccgagcatc
     1981 tgatttgatc tgatttttat aacatgagga tattacaata tactgaaagc aacgaaaagg
     2041 acgtgttaaa tggctaccca tttgcacgtc ctttttgcgc tgttttggag ctgtatcata
     2101 caattaccgc tacagattct gcgtaccggg gtatattgca atctattttc agcaagaatc
     2161 aatcaatagg gacggtttgc gtttaaagag gtagagagaa acagatcaga agggggtgct
     2221 gcatgatatg ctgcccaata atcgtttttt tcgcctgact acaggtattg tcatgctctt
     2281 gctcatcatt tatttgggca ccaaagtaag ttttatattc agtcccatcg tatctctggt
     2341 cagcttgctg gttgtaccgt taatgctgtc ctttttcttc tactatttat tgaggccagt
     2401 ggtagatttg atggaacgaa gaaaaatcaa gcgccccatc tccattttgc tgatttatct
     2461 ggtcattgcc gcgctgctgt ttattttctc atggggtgta tggcctacat tgcgtgatca
     2521 ggtaacgaat ttatttgaaa atgcgccgaa gctcattagc agtctggttg atcaattgag
     2581 ccaatggcgg cataatcaat ccttgagaca agtgttgcct ccgggggaag atccgctgtc
     2641 acgactgtcg gatacgttga atgaggcttt ttcagctctg tccgattatt cggttaagct
     2701 ggtatcgttc gtatcctact tttttatcgt cttggctacc tttccgattt tgctctatta
     2761 catgctgaag gaggggcgca agtttggtcc caaaatgcta aacttctttc ctaaagaata
     2821 tcacaaggac gcgctggagg tcatggagga tatcgacagt gcgctcagca gctttatcgt
     2881 gagtcgggtg ctgataaatg tcgcgctggg tattatgatg ttccttggct ttctaattat
     2941 tggtctgcct tacgccttgc tgctcgcggt catttcgatt tttcttaatt ttatccccta
     3001 cgtgggggct gtggcggctt ccatacccgt cgtcattatc gggtttcttg aatcaccttc
     3061 catggcaatc tggtcgctgg tcgtcgtgat cgctgcccag caaattcagg acaattggtt
     3121 gtcacctgtt gtgtttggca aacaattgga tattcatccg ctgactgtcg tcatactgtt
     3181 attggtcggt ggtgacttgc tcggcatttt gggtatcgtt ttggttattc cgctgtacat
     3241 gtgcgctaaa atagtgatac gcaaggtgta tcatttattt ttggaacaca gggtggaaga
     3301 tatgatggaa tgaatggaat tatcccgtct ctgattgcag ggttgcctga cggttttccc
     3361 tgtctttgcg agtaccggat tgtgtttcaa gatcagaagc gtcagttgaa acagcagagg
     3421 gttctgcgtc tttcgttcgg atcatctgac tcgtaccgtc cagaacgccg ccttcggaga
     3481 tgaccagcgc ggcggcggct actttgccgt acagttcgcc cgtaggcgtg atcgtcagtc
     3541 gtccctctgt ggtgatgctt ccgaatacct tgccggcaag ggtgacgtct cgtgcgatga
     3601 tatccgaacg cacgacagca gattctccga tcacgacggc atgagtgctg cagatatcgc
     3661 cctgaaaatg gccatcaatt cgaatattgg cctcagcctc aatcgtacct tcaaagctgg
     3721 tgccgttagc caacagcgta tcggtcacag gtgcggacag cttttttttg gagtccttga
     3781 acatgttgtt tgcctccatt catttattgt aaggattttg aaaaatatca ttgtacatac
     3841 agtaacggat cgacaggctg actatgcttg acgatctgaa aatgaagatg aggccccgtg
     3901 cttcttcccg tacttcccag aaggccgatg gtctgtcctt tacggactcg ttcccccgga
     3961 gtcacctgca taccgcttag atgcatatac caggactgga atccgtcagg atgctggatg
     4021 ataatgcact tgccccgtgc cccgctggag gctgcctcaa gcacagtgcc cgctcctgcc
     4081 gcatagacgg gatcacccgt ttgtccggca atatccatgc ccgaatggaa agcggatttg
     4141 cccgtaaacg gatcgctgcg atagccgaag ctggaggtca tctggcgtga actgacaggc
     4201 caggccgaag gcttaccttg ttcggcaagc gccagtctgc gggtctggag caactgtgcg
     4261 gcttgcttct gctcaaggtt ctgctgtacg gcgttcgcct gctgaataga gcggggaacc
     4321 gtgcgctcta ccgtgtccag catagattcg atttcctgaa aatcatcctt ggcttgacga
     4381 gtaagcatgg ctgtattttc atgtactgta atcaattcgc ccccggtata gccggaggca
     4441 tcccaggaga gtggagtcac gaccgttttg ctgctactgg tggcagagga ttttccatat
     4501 ttgcggataa attgctgcat ttgctgctcc agttctgtta cacgctggag gcgttcgcga
     4561 atactggtgg cctgattcgt cagctccatc acttcgcggc gcagtcgccc gattgccgca
     4621 tccttgtccg ctaccgtaac atccatctgc aagctctgga cggcaagatt cgtttccatt
     4681 tgggaaatga tatgggaaga acggatttgc agcccgatca cgagtgtaga gatggacgcg
     4741 atcacaaggg tcgggacgag aatgacagcg gctgtagagt attgtagctg cttgggcggt
     4801 tgctgtgcat cacgaatgac gagcaaggtc atccggcgat ttaggcttcc ttttttcata
     4861 atcgctcctt tccggacatc gctcctatcc taatagtgct tggttactat ctattcagct
     4921 taaggggcaa acatgtcaaa aaaattggag cttggtataa aacatagatg tataaggagg
     4981 cttaaacatg ctgtggttgc tgttggtttt aattgttttt atttttcaga ccgggacgat
     5041 cctgctcttt gaatttcgca agccgtccaa ggcggtagcc tggctattta ttttgttctg
     5101 tttcccgctg atcggctttg tcgtgtacta ctttgttgca caggattata agaagcgcaa
     5161 aatggtgcga aaagggggat cacagctatt ccgtgaattc cgcgagcgcc tatggtcgca
     5221 atccagggtg attgagaatg tggaacaaat gcataatcct catttcaagc atcaggagcg
     5281 tctgtttaac cagctcatcc gtatgtcgga aaatccgctg accggctgca atcgcacacg
     5341 tgtgctgacg gacggggaag agaccttcga ggcgatgctg acagcgctgg aacaggcgca
     5401 gtctcatatc catgtagagt tttacatatt ccgggcggac gacatcggta cccggtttca
     5461 ggaggtcatg atccgcaagg cgcgcgaggg tgtgaaggtt cgattcgtgg tggacggtgt
     5521 ggggagctac aatctgccct attcttttat tcatgcctgt aatgaggcag gtgtagagtt
     5581 tcattatttt ctgcccccgt ttttcgcgac gctggatcgg cggattaact atcgtaacca
     5641 ccgtaaaatc gtagtggtgg acggattgat cgggtttgtt ggaggcataa atgtgggcga
     5701 cgattatctc ggcaagtacc ccaaggtggg attttggcgg gacacgcatt tgcagatgga
     5761 aggagatagc gtctattttc tgcaaaatgc atttctaagc gactggaagc tggcctccgg
     5821 ggaacggctg atggatgaga atttatttcc gccgcatacc tgtgaaggag aagaggaggt
     5881 acagattttg agcagcggac ccgatcaggt atgggatacg attcaggaaa tgtgctttgg
     5941 tgcgctggcg gttgccaaga agcggatttg gattaccacc ccgtatttta ttcccgatcc
     6001 ggggatttat gaggcgctta agctggcggc ggtcagcggc gtagatgtgc gaattattat
     6061 tccatacaaa tcggattcaa agctggtgca tctggcgtcc ctgtcctatg tgcaggagct
     6121 gctggaggcg ggcgtggagt tctatcaata tcgtaaagga tttattcacg ctaaaatcat
     6181 cattgtggat gatttgctcg gctcggtcgg gaccgccaat atggacatgc gcagcttttt
     6241 ctataatttt gagttgaccg ctgtactctt tgcccggtca gcgctggagc atctttcggc
     6301 cgattttgaa gaggatctgt ccaactcttc gcacatcgat ttaaaggtgt tccgcagacg
     6361 gccacgatta cagaaaacag ctgaaattct ggctcgcatg ctctctccgc tcctttaaag
     6421 gcggttttcg ccgtttttat caatataatc cggctttatt gagatttatg tgctttttgc
     6481 taactttttt gcgcaaaatc acagttttat ggtatagtat tcatataaca caatcgcggt
     6541 aaaggagaag ggactgcgga tcgcagcccc ttttttggtc caatatacca taatgtaacg
     6601 gggggattta tatatgagtg tagtgagcaa ggaagtccaa agtctgtctg agatcacaga
     6661 tgtgaccgga gagttgacca agatcagcaa aattccagcc aatcctaaaa ataaagcaaa
     6721 acgcctgttt cagcgtgcgg ccatgattat tttcggtgcc gcgcttatgg cagtgggcct
     6781 cgaaatattc ttggttccta acggcgttat cgacggtggg gtcacaggta tttccattat
     6841 ggcctccaag attactggct acccgctcgg tattttcctg accctgttga accttccctt
     6901 tttggttatc ggctacaagc aaatcggcaa aaccttcgct ttatccacat tattcggcat
     6961 tatcgtgatg tctatcggaa ccacgttact acacagtgta aatgcgttga cccctggcga
     7021 accgctgctc ggtgctattt ttggcggtgt cattctcggc gttggggtag gtctcgtcat
     7081 tcggtctggc ggctcgctgg atggaacaga gatcgtagct attctcgtca gtgaaaaaac
     7141 tcctttttcg gtcggtgaga tcgtactttt cgtgaacatc ttcattctgg gcagcgcagg
     7201 ctttgtattt ggttggccga atgccctgta ttccatgatt gcttattata ttgcgatgaa
     7261 aatgattgat attaccatcg aaggtctgga tcagtccaaa tcggtctgga ttattagtga
     7321 aaaataccgc gacatcgggg atgccctgac ggaccgtctt ggacggggcg taacctatct
     7381 ggaaggtgag ggtggcttta caggcgaaag caagaaggtc attttcgtcg tcatcacccg
     7441 actggaggaa gcgaagctga agaacatcgt ggaagattgg gacccgcatg cctttgtggc
     7501 aattggtaac attcacgatg tgaagggcgg acgctttaag aaaaaaggaa tacactagcg
     7561 caaggggaca attcctcggc cgattttacg gctgtggagt tcgtcccctt ttttatgtgg
     7621 cgcgcatatg ctttagaaca tcttcgatgg gctgtggagg gaccttggaa atcaagtctc
     7681 ctacctgatt tagccgttcc tcaatattca gcaaatgata gtcaagcggt gaaacgtctt
     7741 gtcgtacctc gtcccatgtc agtggggtgg acaccgtagc gccagggcgt gcccgcgggg
     7801 tatagggagc ggccagggtt tttccttgat aatgctgcaa ataatcaaaa tagatagcgg
     7861 ttccccgatc cttttttaaa cgttccagcg tgaacaggtg cgggtgcttt tcggtcacaa
     7921 actgtcccac cagcagaccg atgctgcgaa gctcgtcgaa ggttatgcct gtgcggattg
     7981 ggacgataat ttgtacaccc gtggccccgg acgttttggg tacggattcc aaaccaagcg
     8041 aagccagcac ttcaccgacg atgaatgccg cttccataat gcgtggctcc acttctctgg
     8101 acggatcaag gtcaatcatc cattcgcagg gcagcgtgct tccggcttga tgcagcgatg
     8161 ggtgaaattc cagcgccgcc tgattgccga gccatagcag ttgcggtagc gtaccaagca
     8221 ccatatattc aatgccgtca tgcaggaaag tctcgatata gcccggacga ggctgcgggg
     8281 catttttctg gtagaaaaaa tccccgtgaa taccgtgcgg ccaacggatg acggtcagca
     8341 aacggttgtg gctatatttg agcagaaaag gagccagcac tgcaagctta cgaagataca
     8401 gcgctttggt gataccagct tcgggccata gcggtttatc cgggttggtg ataggaattt
     8461 ccagaccttc gatggtaatg atgcctttaa cagcttgtcc catacgtcta cgctccttct
     8521 tttaacctgt tataagctga actcgaaaaa atgtacatgg aaacggagta gacggaatga
     8581 tgcacctcta gatgtagtta tggattaaca tgagcgtcat gtacagaaat tatccgtcaa
     8641 agggattgac aagatacaat atgtatcata aatttataat aaaatacgta gtgtatctat
     8701 taaatgtctt gagcagaggt agaggaggag tttccttgat tgataagcaa ggcgagggac
     8761 tggttttcct gcttagtgtc ccccgaagtg gaagctcgct agtgactacc attttgcaaa
     8821 accactcccg cctgtttgcc acgcaggaaa tgtggttcct gctcagccta catgatcttc
     8881 cccagtcgca aacacgtccc tatgggggaa ctggaatcat ccggcaattt tttaacggta
     8941 tggttcctcc gcacgtattg gaacaggctt cccgatcgta tgcacttgag atctataacg
     9001 gtttgcttga agggactaac gcaaatatgg ttatcgacaa atccccgcgt tactatacgg
     9061 tgctggaatt tatagaccgt cttttcccgg cagcccgcag ggtatggctt atccgtaatc
     9121 ccttatctat tgcggcttca ttcaaaaaag ttaaccaaat gcgtggcgaa cgttttcatc
     9181 tgctggagga gctggaaagc ccgcatttta atatgaagat gacggatatt acggtcggtt
     9241 tgttccgtta tgcacattat tttgccacac ctcatccgct tgcatacccg cttgtgtatg
     9301 aacaacttgt agccaatccg gcggtggagg tcgggaggct gtgcgatttt ctgggtgtcg
     9361 attatgaacc gggcatggaa aagtacgggg attttgcgga tacacctaaa tccagtcttt
     9421 tttacagcat gggagctggg gatccgttcg tgggggagca tgaacagacg catcaggatt
     9481 cggtacatag ctggcaacat ctgttgaaca aaaaggaaat cgagctgtat tgcagaagca
     9541 tcggagctcg tatgtttaca caactcggct acggggaagc actggagcag gccgagcata
     9601 taacccgggt aaggtttgaa gaggaagccg atgtggagct actaagtcgg cgtacgagcc
     9661 agtttctcca gcaaagcggc tttgagtgga agaacgctta tcggatgctg gaaaagcagg
     9721 gtgcggataa cagggggttt ataataaaag caggacagca tcctgtactt caagattctc
     9781 gacagaatga tgctgtacag gttgtaaatg atagacggct ccaatcgctg gaaaacaggc
     9841 tggcacatag ctatgaggag cggaatcgtc tgatcgcaca gctccaaacc taccaacgca
     9901 gaaatcaacg gctccgatct cgtatcccct ttgctcgtca tttggggcgc tgggcatctg
     9961 tagcgctatc agttatggaa aaagaaaaag gggggaaaac gtgagtgcga ttgcaggaat
    10021 atacagcttc ggacataagc ccgtctgcac cgaagaaggc ggtaaaatga tgcaagctct
    10081 gcgaaaatat cccgccgacc gcgtttgcgc ctggtgtgag ggttctatat tcttgggctg
    10141 ccacgcgcag catgtgacac cggaatccat ccatgagcgt ctcccttttt atgacgagga
    10201 acggaatttg gcaattacgg cggatgcgat tattgacaat cgatccgagc tgtttgaacg
    10261 gctgggggtg ggacaggaac ggcggcaaga catcacggac agcgagttaa ttttgctggc
    10321 atacgacaaa tgggcgctcg acgcggcccg ctatctgata ggcgattttg cctttgtcat
    10381 ttgggatgcc gggctgcaca ggttatatgg cgctcgtgat atggcaggaa gccgcacact
    10441 gtatacatac gaacatgacc gagggtttgc attcagtaca gtagtagccc ctcttctgac
    10501 gttgccttcc ctgcgaaaag aattgcatga gccgtggctg gcggaatttc tgtcgatccg
    10561 cgccatgcag gaatccgtcg atattgggac aactggctac aagcatataa accagctccc
    10621 gcccgcccat tggttcacca tggaggaggg aaagtcaacc atccataaat atgcatctct
    10681 ggatgatgtg gagccgctgc ggctcaaaac cggcggcgag tacgtggagg cttttcgcga
    10741 ggtattctca caggcggtga atgccagatt gcgcacgcat cgtggggtgg gagcggcctt
    10801 gagtggcggt ctggattccg gtgcggttgc cagctttgcc gcgccgtcgc tgcgattgca
    10861 gcaaaagcct cttcatgcgt acagctatgt gcccgtacag gattttacgg attggacacc
    10921 atcgacactg ctggcgaatg aacgggctta tatccaatcc acggctcgat atgtgggcaa
    10981 cattcacgaa aattacctgg attttgaggg gaaaagccca ttttcagaaa ttgatatctg
    11041 gctggaattg atggaagctc cctataaata ttttgaaaat tcgttctgga tcagaggctt
    11101 ttatgaaaaa gcacaggaac aaaatgtggg tgtgctgtta accggagcgc gaggtaattt
    11161 taccatttcg tgggggcctg cgctggacta ttatgcccgt cagcttcgtc gtttgcactg
    11221 gctgcaatct tttcagggat tgtggcagta cagcaagctg accggaaggc gagtatcgca
    11281 tttattaccc gtgatgctga agaaagcgac ctcgctcgat tctcgttcct ggttacgcgg
    11341 cggtaatcgg agtccggttc cttcgctcat tcacccggag tttgccaagc ggatgaatgt
    11401 ggaggacatt ccgactttga gtggaaccgg gtggatgaag aatgcagatc aggcgagaaa
    11461 agagaagttc acgaatttgg cgattgcgaa caaaaatggt gtggttgcga ccaagctgtc
    11521 gctgcgttac ggactgtggg aacgtgatcc gaccggagac agccgggtga tccgcttttg
    11581 cctgtcggtg ccctttgagc aatacgtgca aaacggccgg gatcgcgcac ttattcgcgg
    11641 agccatgcgg gattatttgc ccgatgatgt ccggttaaac cagcgtgtac gcggtgtcca
    11701 gcctgcggat tggctgcacc gtatgctccc ctgctgggag acgtttatgg gggaacttca
    11761 actgctgtgc catgatttac atgccgccga atttctgaat atcgatgtca ttaaaacggc
    11821 tatggcgaag tttcgtcaac cgcgaccaga gcaggcgtcc gatcccaacc tacgattgct
    11881 gatgcacagt ctgattgtgt accgctttat acgcggattt aactgatgcg gtcttatccg
    11941 gtaggacaga tacgtcgctc gttggagggg aggtgatgac atgagtaaaa aagaatggca
    12001 agagccaacc atagaggcgc tggatattaa ccagacgatg gcaggtaagg gctggaaaca
    12061 gattgactgg gtatctgacc atgatgccga tctgtataat ccaagctaga gagtggcaat
    12121 tattcaatac acagccgtct ttatttcttg gggtttgaag gctttgctcg aagaaataaa
    12181 ggcgggattt ttaaagggca gagggagtga gtcctatcgt gcatgacagg agtaccaatg
    12241 ttaacctgac gatgtataca gcctttggac tcaaacttgc cagcgagctg tatctgcctg
    12301 aattgatacc cgcagcaccg ggagcggtgg aggatgtggt cattcgtcag actgatttga
    12361 cagcatggag cgatcagttg gagcaggcta attttgtgat gcagggtgag cgctttatgt
    12421 tctatatacc ggacacagcc atttacgccg tcaggagagg cagggaaatt gaagtatgtt
    12481 cttactccgg tgctgatccg gacacggtaa ggttgtttgt gctgggcaca tgtatgggtg
    12541 tccttctgat gcagagaggg atagtgccta ttcacgggag tgcggtagtt atccgaggta
    12601 gggcctatgc ttttgtaggc gaatcgggag caggtaaatc gacgctggct gctgctttta
    12661 cccaggcagg gtatcggata gtcagtgatg atgttattgc tatgcaagct acggcttcca
    12721 aaaccatagt ctatccggct tacccacagc aaaagttggg tctggaaagc ttgctccaac
    12781 tggaggcttt acagggtaat aggcatgcac acaaaagcaa tcacgggctt gttttaatgg
    12841 acggcaatcc tgcgatgctc aaatatggac atttgcgtaa gcttacaggt gaactgaata
    12901 aatatgccgt gccgagagtg gactacttct acaacaaacc gcttcccttg ggaggtgtat
    12961 tcgagctggt ggcagagtct ccaaatcgtg agttccaatg tgaagggaag ttgccggcgg
    13021 ttatggaaca acctttgaac atgctggagt gcttgcatac gttattgctt catacatatc
    13081 gcagggtgat cattccgcga atgagtctgg gtgaatggca ttttggaacg gtagcccagg
    13141 tggcccggca ggtggagggc tggcgactac tgagggatag ctctgctttt accgcgtccg
    13201 aggttgtaca ccgggtactt gatatcattt gtaaggagga aaacagctgt ggcagctact
    13261 cattccatga aggatcatga ccgtgtcatt cacggtgagg aagtctatgt cagtgacatg
    13321 gacggggaaa aggtcatgat gagcatcaac acaggaaaat attataatct cggcttcacg
    13381 ggaggccgaa tctgggagct ggcggaatcc tgcccttcac tgggggagat cgtagctgct
    13441 ttgacggatg aatatgaagt ggacgaagaa cggtgcagac agcaggtaca tacctttgtg
    13501 gctgaactgg aacgggaagg actgctaaag cttctgaggg agacggttta aaatgtggat
    13561 tcaacgcctt cggcgtctat ccccggagat caggagactg ctgccggaag cctggctgca
    13621 actcggatgg gcgcgtcttc accagcatcg tccatttgaa gattatgcac gcggttgggg
    13681 aatacgtatg gaagaaacct cttgggagtg tgatgcccgg cagaagcaag acgttcggca
    13741 tatttcacat gcggtggagc tggcaagccg ttatacccct tggcacagta gctgtcttgt
    13801 gcaggctgtt gccgcaatga cgttgctggg tcgcagaaag ctggactgca cgctgtatct
    13861 tggcacagcc aagaatgctg cgggacgttt ggcggcacat gcctgggtgc ggagcggacc
    13921 gatttatgtt acgggcgaac gagagatggg ggcgtttacc gtagtgggta ccttcggcag
    13981 gcgtgctgtg acggaccaaa atacgaagat tgctgaaagc atgtccaccc atacagctct
    14041 gaaatctgac cgctggaatg aggatcagga attaacgctg ctgctctttt tactgcgaaa
    14101 agatgccact tcaaggctgg atacaatcga tgctggtgat ctgcatggat tggattgggc
    14161 ccgcttgcta cggctggcag aacaccatcg ggtggtacct gcggtatatc ttcggttgaa
    14221 aagaataaat catccagcca tccccgctga aatgctgcgc aaccttcagg cgcaatatca
    14281 ccggaacacc ctgcgtatgt tgcacctgca agcggaagcc gggcgggtga ctgggctgct
    14341 catgaatcat ggcatccgtg tacttatgct caagggtcct gccttggcgc agcaattgta
    14401 cggggatgtt tccctgcgta cctccaagga cgtagactta ctcattgctc cgggcgatat
    14461 ggatatggcg gagcaatgga tgcaggaagc cgggtatgta cccaaaagcg gagaagcgcg
    14521 tgtcctgggc agttggaaat ggaaggacca tcatgcatcc tttcttcatc cgcataagcg
    14581 ggtagagata gagctgcatt ggcggctcca cccggatgca ggcggagaac cttcttttga
    14641 ggacctgtgg aaacacaggc aaaccgatga agtcacagcc acaggagtac cctgtatgta
    14701 cacgcttggc agcgagcacc agtttctgta ccttagcgca cacggggcgc gtcacggctg
    14761 gttcaggctg cgctggctgg tggacatcga caggcttgcg gtacgcgccg tcgattggga
    14821 ggcgcttctg ccgatgatgc gccgatatgg gggcctgcct gcgggcgggc aggcttgggc
    14881 gctcgccgct gcgctgctgg gcacctcgat accggagccg ctgcgtcagg tagcggctac
    14941 acggctggcg cacaggctcg cgctgagcgc gctggacttc attcaggcca gcgacccggt
    15001 agccgaacca acgatccaac agccaaccag tcgatcctat ttgctctccc taaaggagcc
    15061 gagccaccga ttgctgtacc tgatcagccg tttgcttcct tctacgggcg atccggccgt
    15121 tttaccgctg cctcgccagt tacattttct gtacatccct ctacgtccat ttctctggct
    15181 aaaacggcga ttctcaaagc actgacctga taaggagcgt gcattatgta ccacctgcga
    15241 ttatatatga ctaagctgta tgccgtgaac ggcggtgcgt tatttctcaa tattggatgt
    15301 atgatcatcg tcagcttgct ggaggggttg ggtatttaca tgcttgttcc catgctggcg
    15361 gctatcggca tatttggcgg tcatgcaggg atggccatcc tgtcaggcgg attggatcat
    15421 ttcttgtcaa acatccctaa aagctggctg ttgccgggaa tgctgttgct ttttgcgttg
    15481 ctactcatag ggcaggctct gcttcagcgt taccagtcca ttctgaattc acggattcag
    15541 caacgattca tgcgttccct tcgaatagat gtatatacct cctttatgaa ggcccaatgg
    15601 actttttatt tgcgtcagcg gaagtctgat ttcagccatg tgatgacaac cgagctggcg
    15661 cgtgtcagtc agggaaccaa tttgctcctt cagctcacca cagccgttat ttttacgctg
    15721 atccagattg cgctggcttt ttggctgtct ccttctttaa ccggactggt gtttctgtgc
    15781 ggattggggc tgtttgtcgt gtttcgcaga tccattcaaa acgctaaaca actgggcgac
    15841 cgtaccaccg agctgtcgca ggtttatttt gccggaatta ccgaccatat gaacgggatg
    15901 aaggatatta aaagcaatct gctggaagcc gcgaatatag actggtttcg ctccttgacc
    15961 caacggatgg aggacaatac aacccagttt gtacggcaga acgcaaccac acaatttttt
    16021 catcgcacag ccgctgctgt atttgttgct tgcattatgt ttgtatcact gcaatggcta
    16081 catgtctctc ctgaaaagtt gattgtgctc atccttatat tttcccgctt atggccaagg
    16141 tttgccctta ttcaagcgag cctggaatat atcatgtcca tgctgtctgc ctttgaaagt
    16201 gtgaccaagg tacagcagga atgcgaagct ttctcagatc cgtcgctaac ggcacttaca
    16261 acctttgaga ctcgcgtttc aagcgttcta tcggcaaccc atcaatctgt attagcatct
    16321 acaacttcat ctgtacgcca acccttgtat ctacgtacag gcattgaatg cagtggtctg
    16381 gattatcggt atgagggtac agcagcgctt gcattacacc aaataaatct gttcatccct
    16441 gctcggggaa tgacggctat tgtggggaaa tcgggcgcag gcaaaagtac aatggttgac
    16501 gttctgatgg gatttttacg accaactcag ggccagatta aaatagacgg acatatactg
    16561 gacgacgagt tgttgccaca gtggcggcaa tcgtttggct atgtgtcgca ggaccctttt
    16621 ttattccatg ccaccgtccg tgaaaatttg aagctggcgg atgcggatgc gagcgagcag
    16681 cagttatggg aagcgttaca ttttgcagcc gcagacgggt ttgttgccag attgcccgaa
    16741 ggactggaca cggtaatcgg ggatcgcggc attcgtctgt caggagggga acgtcagcgg
    16801 ctagtgttgg caagagctgt cctgcatcgt cctccagtac tcattctgga tgaggcgaca
    16861 agtgcgctgg atggagagca tgaagccgat attcaggcgg cgctggagcg gatgaaaggt
    16921 caaatgacgc tgatcgtcat tgcccatcga ctgtcgacca tccgtcatgc cgatcagatt
    16981 gtcgttctgg agcagggaga gattatacag caggggaatt accgtcaatt ggtgcaggag
    17041 gagcgggggg cgttcagtca actgctgtct taccaaagca gtgtgttctc caccccttag
    17101 cctgttctgt tgacaatgct taactcccca ctggatatgg aatgggcaca gtttcaggtt
    17161 tccttgtgtt tggctgtgct tcttttcttt ttgatcggag ttggagaaac ggcatctcct
    17221 gccactgctt gttgtgttgt tgtggctgct gctttacgcg cagggcgttt tttcacgtca
    17281 gggccgggat cggtaacgac aggcttcact gcctcgatgc tggcctggag tgcagccatc
    17341 aagtccacga cattggcctg tggctgggac ggggcgattc ggatctcttc tccagccact
    17401 ttatgctgaa tgagatccag cagccgctcg cggtactggt ccgtgtattt tgctgcatca
    17461 aaaggtgtag atagctgctc aatgagcatt tttgccatgg tcagttcctt ctctttaact
    17521 tcctcctgcc ctggcagatt aggaacctgg gacactgggc gaatttcatc cgggtaaaac
    17581 atcgtctcca ccgccaagca ttcatccagt acacgaatag ccgccagact gcttttggat
    17641 cgtatcgaga tttgagcaat gccaattttt ccggtatcct tcatcgcatt cataagaagc
    17701 ttgtaagcat tggagcctgc ctgatccggg gacaaataat acgttttttg aaaataaatc
    17761 ggatcaatct cctgcaagtc cacaaaatcc aaaataacga tatttttatc cgcttgtccg
    17821 ctgatttgct ccagttcctc cttatcgaac atgacaaact tccctttttc gtattcatag
    17881 ccttttccaa tttcctccca ttcgacctcc ttgtcacaaa cgggacactt tcgtacataa
    17941 ctgagcggac ttccgcattc cttgtgaata taacgcatgg aaatatcctt atcctctgtc
    18001 gccgaaaaca tcttaacagg cacatgaacc agcccaaagc tgatcgcgcc tttccagacc
    18061 gtatgcatac cgccagtcct ccttttcttt aatccgcatg ttgtatcctt cgattccaac
    18121 gcttggctgt gagcatatcc acttttcact tagatttttc acttagtatg cttcggaggg
    18181 ctacatcgca taacacaatg atttgaggtt gttaagttac atgggttata ttaagataag
    18241 gaataataaa taatcttgcc attttataag gaaggagtgt tcatgtcatg aagaaaagat
    18301 cattaaactt tatatctttt ggatatggat actctactgc tgtttttttc taaaatcatt
    18361 tttatgggtg gagtctgcct aaaaatggta ggagaaacgg tagaaaaatt ttaaaatgac
    18421 gaggtcgata aaatgaaaaa tgaaaaaata actagaaaaa acccggcagg tatgccgaaa
    18481 ccagtaggga attacacaca tataactaaa attcccagaa attcagagct attcgtgact
    18541 tcaggtcaaa tcggagtaga tcaaaatggc caattcccag aaagctttaa cctacaaatc
    18601 agcaatactt ttaataacat taaatcagtt ttggacgccg aacaattaac cgctgacaat
    18661 attattaaag taaatgtttg ggcaactgag cagatagatt gggattacat gtattcccaa
    18721 tgggaaaagt tattcgggaa tgattatcct gcaatgacga tcggctacct tactgctcta
    18781 ggattgcctg aaataaaaat tgaaattgaa atttgggcag ctaaagcata aaaataataa
    18841 ctcatttata ggatggaatc atagatagcc ccggtcttcg tgagaagctg gggctgtttt
    18901 atgtttaagc tcatgaaaaa tccgcttgcg catggttaca gcttttttgg tgcatagtaa
    18961 ggtatatccg attcaaaagg aggtacaatt tatgcccgga aaatcctatc ctcggcaaat
    19021 cagacatcgt gtgggtcaaa gccatatcgc ctttcgggga cccgccggag gcgaacagga
    19081 tgcattgcca cccgagtttg ccctttctca tggaatccag ccgccttttc ctgtagctgt
    19141 gggtcatgtg gatttggagg ccgtggtttc aacctcgcct tctcatagca tcccttcatt
    19201 ggacgttgaa cggattatag atgaggacta ggtgaacctg tatttctgaa tacatggata
    19261 caaaacaaat catcaggagg agatcagcat gaacgtggaa cgagcaaaag cgatttacaa
    19321 ttcatccgaa aacattgccg tgcaattaga gggtaaaccg atctggatcg agcatgtaga
    19381 tgaagcaaac ggtatggcta ccgtacaggt gggaagcaac cccggtaata ctcaaaccgt
    19441 tcgggtggat cgtctggaag agcgatagga gatgggcaca aggttaatga ttggctgaca
    19501 ctgggtatct gttggacgag ccagctccgg gctttcaccg cagaatgctg cttgaatggt
    19561 ccactccaac aaaaaaaggc tcgcaattgc tcaatgagca attagcgaac cctacttgta
    19621 aaaatgttta cactgcaata gccttcaaat gtggtgaaac catcagttta gcctctgttg
    19681 ccatttgaac gtcttctacc gacaaacccg gagcaatttc cttcagcatc agccctttac
    19741 ccggaataac atcgatgaca gccttttcgg ttactatggt ctttacaaca tttacagcgg
    19801 tcaggggcag cttgcattgt ttcagtattt tcggcgcccc atttttgttt acatgctcca
    19861 tggctataat cactctcttg gctccgacca ccaaatccat ggctcccccc ataccgggta
    19921 cctttttccc agggatcatc cagcttgcaa ggttgccttt ctcatcgacc tccaaggcgc
    19981 ccaaaacggt gatatccaca tgtcctccgc ggatgataga aaatgaaagc gcactgtcaa
    20041 aaaaggaagc tccttttaca gatgtaacgt agtttccgcc tgaatcgata caatcgagtc
    20101 tttcttttcc ctgagccgct ttgggaccta caccgaggat tccgttctct gcctgtagca
    20161 taatatggat gttttcgggg atatagtcca ccaccattgt aggcattcca acaccaaggt
    20221 tgacaacttc gccatctttg aattcctggg ctattcttcg aacaatcaat tctctgttat
    20281 tcatgcgtgt ccacccacct ttacaatcgc gtcgacaaat atgctgggaa cgttgacatg
    20341 attggggtca atttcccccg cctttacgta ttcgtctgcc tgagcaacta catactctgc
    20401 tgctgtagcc ataaccaaat taaagttgcg tgaagagccg ttaatgacca gattcccctc
    20461 ttcatcagcc ttatgggctc tgattaacgc cacatccgct ttgagcggca gttcgagcaa
    20521 atactccctt tcgtcaattt ctattttctt ttttccttcc tctaccatgg tgcctacacc
    20581 tacaggtgtt aaaacaccgc ccaaaccggc tccccctgcg cgtatttttt cagcgagcgt
    20641 gccttgcgga aagagctgaa cctccgcttc tttcgtcata aggagccttc ccgtttctgg
    20701 attggagccg atataggatg caaaaatccg ttttactctg ccacttttta ccagattata
    20761 gatagataat tccggcgtgc ctgtatcatt cgaaataatt gttagattac tggcggaatt
    20821 tgtgtcgaca agcgcacgta ccagatcctc cgggaaacct cctgccagaa aacctccgac
    20881 catcaccgtg tctccgtctt tgaccttctt aactgcttct tcagcggaga ttactttgtt
    20941 attcatggtt ccttctcctt atatatatat ttttaggaaa gcaaacttta ttggagataa
    21001 tcgtagagga ctcttccata tggaagcgtt aaatcggcaa taaaatgttt tccgccaaca
    21061 taagcttgaa ccggcaaatc tgccacagga gcattgacat gggggatcag gcttaatctg
    21121 gcaggccctg accaggcgcc ttttacagta atgttttcga gattatacgc tactaactga
    21181 gcaattttgg gggtaccgtc aatatcagga attaatttca aattaacttg cgtttttgcg
    21241 atcgctttag ccgtttcctg ttcatcaaga atattatatt tgaaaggcat ggttcccatg
    21301 gccaccagga cgtgattata atgcaatgta cccgtcagcg tctccgtatc ctcaacgatc
    21361 aggcgaggct tcgcccattt tttcggaaat ccccagattt cacgtccccc aagaatagca
    21421 ggcgcgttat ccaaatacat ttgggcaaca aaattacagg gttctccttg aaaagtacac
    21481 ggaatgacaa taccgctttc ctcatagctt cctaaaccgg atgaatcggg catcttgatc
    21541 cattcatagg aaacagtatt gcttccatcc ggctgaagag gttccgggac cgcttgtcta
    21601 atcgcagcgg ggtcggattc ataggtaatg ataaaaaatt cccggttgat gaagcggcat
    21661 ggcgggcgcc cataactgcc gctggccgca ggcatggatt gaagtgaaag tacatctttt
    21721 tgattcatag cgattctccc ttccttatta agaggtagtt ccaaaagtca tcttttgaac
    21781 acgcatttta aatgagtgca ttttcaacca gcatcgctat tcccattccc gttccgatgc
    21841 ataacgaggc gatgccgtaa cgtgaagatc ttcgcgccat ttcatgaacc aacgtaacca
    21901 aaatcctagc accgcttgca ccgacaggat gcccgatcgc gatcgcgccg ccattgacat
    21961 tcaccttctc cggattggcc ccaagctctt tcatcaccgc tactgcttgt gcggcgaacg
    22021 cttcattaat ttcaaaaaga tcaatgtcat caatggacaa tccctgttgc ttaagaaggg
    22081 tcgaaatggc tttcaccggt cccattccca tatatgcagg gtcaacgcca acaagtgaat
    22141 aacccttgat atatgccaac ggctttaacg catgttcctt acatttgtct tccgacacta
    22201 caagcatagc cgccgcgcca tcattgattc ctgaagaatt tccggcggta accgttccgt
    22261 tctccttaaa cgcagttttt aaatgagaaa gtttttcttt cgttgtattt cctcttatgt
    22321 gttcatcctc cgtgaaataa atagtttctt ttttggtttt gatcatgacc ggaacaatct
    22381 gttcttcaaa aaccttgttg ttttttgcct ctacagcctt tatctggctt tgataggcga
    22441 attcatcttg ctcaagtctt gaaattccat atttatcggc aacattttct gcggtaattc
    22501 ccatatggta atggttgatc gggcatgtaa ggccgtcggt caccagggag tctaccaatt
    22561 caccgttgcc aagcttgtag ccgtttcttg cattccttag cagataagga gcgttcgaca
    22621 tgctctccat gcctcctgcc aagacgatgt tgccttgttc cgctaatatt gaattgtagg
    22681 ctaaaccgac ggcatgaagt cctgacccgc aaaccgtgtt tatcgttgat tcgggtacat
    22741 caatggggat accggctttt agtgccgcct gtctagcagg attttggcca ttgcctgcct
    22801 gaagaacatt tcccaaataa atctgatcaa ttaaagcagg ctctaattta ctttgctgaa
    22861 ggcatgctgt catcacagtt gctcccaatt caggagcgct taggggcgca agggttttgt
    22921 taaaagagcc gaccgctgtt ctcaacgggc ttactaaagc tacttttttc ataaaaaatt
    22981 cacattcctt tcgctgtgtt caagacacaa tacatccatg actgcaattc aattcgtaaa
    23041 ttccgctttt accttacgaa gcgcagcgac tgcaagatac atttacatgc gggcatatca
    23101 tggtgcctaa gacagtgagt gtgacggttc gatcgccttc tttctttcgt tggaaattaa
    23161 aaccagtttc atcatagttc taatgcaaat tttgctcaat gttcaaatat ttacatatat
    23221 ctaagtacag atgtttataa agccatatac tccaaaatag ataggtcatt ctaatgtttt
    23281 ctgttaattt ctctattttt ctgaaaatca tgatcataaa atgaattttc tgttaaaaat
    23341 gaaatttcta atcaacacgt gaaaaaacga ggccaatcgt tgagtttgca catcttcctc
    23401 ttaatccgcc cttccttttc ttcgcaaata gcacctaact tatcgctggg aaataaaaaa
    23461 aagccattca caattttctg aagacggctt tgccattaaa tattcatgat cctcgtcata
    23521 attgtgccag cttgcttctt gttaacggtg tcatcccaat tacacaaaaa gctcctgaat
    23581 ctccacagaa ggaaattcat tttataatgt ttaatccagg aaacagggtg tatagtatgg
    23641 ttaatgtttg agggaggtga gacgtatgga ctttaacata tgcttgtttg atgattttga
    23701 aacactggat gtattcggac ccgttgagat ttttggccgc ctgccagaag agtatgactt
    23761 aaaatatttc tctatgaacg gggggatgat tgagagtcgg caaaaaacca agattgttac
    23821 tgatcctatt gcacaagcaa agcccgatgg catattcatg atcccgggcg gacaggggac
    23881 aagaagttta atccatgacg atcaatttat gaaacaggtc aaagagattg cggaacagtc
    23941 ctgtttttgt ataaccgtct gcacaggttc tgcgctgctt gctaaaa
//
