LOCUS       NZ_PNXQ01000008        21455 bp    DNA     linear   CON 30-JUN-2024
DEFINITION  Paenibacillus terrae strain PIC167 Contig_008, whole genome shotgun
            sequence.
ACCESSION   NZ_PNXQ01000008
VERSION     NZ_PNXQ01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Paenibacillus terrae
  ORGANISM  Paenibacillus terrae
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 68576)
  AUTHORS   Gomez-Lama,C., Legarda,G., Ruano-Rosa,D., Pizarro-Tobias,P.,
            Valverde-Corredor,A., Niqui,J.L., Trivino,J.C., Roca,A. and
            Mercado-Blanco,J.
  TITLE     Bacillales members from the olive rhizosphere are effective
            biological control agents against Verticillium dahliae
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 68576)
  AUTHORS   Gomez-Lama,C., Legarda,G., Trivino,J.C. and Mercado-Blanco,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-JAN-2018) Proteccion de cultivos, Instituto de
            Agricultura Sostenible, Av. Menendez Pidal sn, Cordoba, Andalucia
            14004, Spain
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2017
            Assembly Method                   :: Megahit v. 1.0.3-29-g707d683
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: GCF_000235585.1
            Genome Coverage                   :: 130.81x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_005217525.1-RS_2024_06_30
            Annotation Date                   :: 06/30/2024 04:15:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,015
            CDSs (total)                      :: 4,939
            Genes (coding)                    :: 4,759
            CDSs (with protein)               :: 4,759
            Genes (RNA)                       :: 76
            rRNAs                             :: 5, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 1 (5S, 16S)
            partial rRNAs                     :: 2 (23S)
            tRNAs                             :: 64
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 180
            CDSs (without protein)            :: 180
            Pseudo Genes (ambiguous residues) :: 0 of 180
            Pseudo Genes (frameshifted)       :: 50 of 180
            Pseudo Genes (incomplete)         :: 143 of 180
            Pseudo Genes (internal stop)      :: 19 of 180
            Pseudo Genes (multiple problems)  :: 28 of 180
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:51:51
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 10132
            Orig. end                         :: 31587
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            PNXQ01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21455
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21455
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21455
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11455](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11455
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    286..300
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.04"
                     /tool="antismash"
     misc_feature    719..730
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    789..804
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            complement(1251..3425)
                     /locus_tag="C1I60_RS07320"
                     /old_locus_tag="C1I60_07365"
     CDS             complement(1251..3425)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019685868.1"
                     /locus_tag="C1I60_RS07320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07365"
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_137061183.1"
                     /transl_table=11
                     /translation="MEQQLNSYLQNMTLEEKVDQLLQLVGAFFEDAETDGQITGPMASL
                     GITEETVRNVGSVLGIAGAEEAIRVQQAHLSKNRLGIPLLIMADIVHGFKTIFPIPLAI
                     GCSWNVQLAEESATIAAREASVSGVHVTFAPMVDLVRDPRWGRVMESTGEDPYLNSVFA
                     RAFVRGFQGKDLTNDTDRVAACVKHFAAYGAGEGGRDYNTVDLSAWQLREYYLPSYKAA
                     LDEGCEMVMTSFNTVEGVAATGNKRLMRDLLRDEWGFDGVLISDWAAIKELIPHGIAED
                     EREAAQKALLAGVDIEMMTSCYNGHLPELVRSGQLDEALVDEAVMRVLKLKQKLGLFDN
                     PLRGADPEREREVVFCEAHRAVAKELAIQSCVLLKNDSILPLNRSQHIALIGPFAESGD
                     ILGSWSWSGSQEEAVQVIDGFKSKISSSLLSVATGCSIDEISEEQYAEALQAASQAEVI
                     VLALGERSDMSGEAGSRSDIRLPQAQLELVKRLKTLNKPMVAVLFNGRPLDLHGVIEEA
                     DAVLEAWFPGGEGGAAIADLLYGDAEPTGRLTMSFPQSVGQVPVYYNHFNTGRPQLDPN
                     TKERYVSQYLDVPNEPLFPFGYGLSYTKVAYDSVQLSSDTLTPGQALTVKVRVTNTGTR
                     PVEETVQFYVRDISGDTVRPMKELKDFRKVLLASGESREVEFSLIESQLRYHHADLSFD
                     SDSGEFAVFTGPNSRDTTEGRFRLVKETGK"
     gene            3919..5172
                     /locus_tag="C1I60_RS07325"
                     /old_locus_tag="C1I60_07370"
     CDS             3919..5172
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017425689.1"
                     /locus_tag="C1I60_RS07325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07370"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_137061144.1"
                     /transl_table=11
                     /translation="MMKRTLGIVLASTLLLGGALAGCSSKDESSGKDANGKTTITLWGM
                     GAEGKLLPEIAKDFEKENPDIHVDVQALPWDNAHDKLLTAVASKSGPDVVQLGTSWVPE
                     LASAGALTDITPYISKYPELESKNFFSGAVDTAKFEGKPVGVPWYTETKVLFYRSDLLK
                     QVGYNEAPKTWEELSDAAQKLAARGKGKYGIAINAKEQSLGFMFALQNGSKLIDEQGNP
                     LFNQPPFVEAVKYLNTFFQNGSNALDLGIDSVQGLQGDGIVPMFISGPFMIREIKSKAP
                     ELDGKWNIAELPGKVNNLSVLGGSNLSIMQFSKHPEESAKFLAYMSKPETQLKWMELSS
                     TLPAATKSWEDAKLKNDPMLQTIRKQLDHSAALPQLAAWEEVSQQFIKSFERIYRGQAD
                     VQKEMDDFNQQAASIMKK"
     misc_feature    complement(3922..3937)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.45"
                     /tool="antismash"
     gene            5209..6093
                     /locus_tag="C1I60_RS07330"
                     /old_locus_tag="C1I60_07375"
     CDS             5209..6093
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279338.1"
                     /locus_tag="C1I60_RS07330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07375"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_137061145.1"
                     /transl_table=11
                     /translation="MKGSSQKLAPYLFIGPSIILLTLFSLLPILLALVISFTDMDLSGL
                     VNYDNIRFIGLENYKNVLIDPSFLKSIGNTLFFVIIGVPLVLLFSLSIAILINMGKSRA
                     FKVFRVVFYLPSVTNVVAVAVVWSYLYNPTLGLFNYVLGMMNLDPVPWLTDPTMAKISL
                     ILLAVWRGIGLNMIIFIAAIKGIPGSYYEAAQLDGANTWQQIRYITLPQLRYAIFFVSI
                     TTMIGWLQFFEEPFVMTKGKPLDGTLSASLFIYNNGFQFSKFGYAAAGSFILFFAIIAV
                     TLIQFRLQNKAES"
     gene            6112..6966
                     /locus_tag="C1I60_RS07335"
                     /old_locus_tag="C1I60_07380"
     CDS             6112..6966
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308375.1"
                     /locus_tag="C1I60_RS07335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07380"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_044646507.1"
                     /transl_table=11
                     /translation="MKTAVQQARANSRSGEKTFQWFVAILLTVGGLLMVLPFAWMILSS
                     FKTESEVTQIPPTIWPQHFTLDNFKTLFDSMAFGTYLTNTLVIVLASFFGLFLNAMAGY
                     GFAKFKFKGKGFLFYLVLATMMVPGQVTMIPVYLILNQMGLTNTMMGIVLPGLVGAFAI
                     FLFRQFMSDIPEELLEATRLDGAGEFRTFLQIVLPISTPILAVQAILTFIGGWNSFLWP
                     LIIANDEKLYTLSVGLSLLKGQNESQFALQMAGSTFMVVPIMIIFIVFQKYIIENYTIS
                     GIK"
     gene            complement(7119..7763)
                     /locus_tag="C1I60_RS07340"
                     /old_locus_tag="C1I60_07385"
     CDS             complement(7119..7763)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="C1I60_RS07340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07385"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_353505561.1"
                     /transl_table=11
                     /translation="MMVMSFITFMIFHPSKGGLNMPTTMVTDCCEGDQCTRQYNCFYNQ
                     ICELYLDDVYRFCIHLLKNELQFRCIAEECTQDTFLTARQQLCKLKLHPNVKGWLYLTA
                     KHFVHKSLRRYYTQKKHETMFEHEACSLSISVEEDWEKSRFQDIDQIINSILTQLSKKE
                     YELYQDYFLQNMSISILATKYNISITATTTRIYRLRKTLRTLSHQYYLTHM"
     gene            7917..9668
                     /locus_tag="C1I60_RS07345"
                     /old_locus_tag="C1I60_07390"
     CDS             7917..9668
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007428307.1"
                     /locus_tag="C1I60_RS07345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07390"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_137061147.1"
                     /transl_table=11
                     /translation="MKESIVFKRLAGLFRTHLKSVTIILTCLIISAGMNMLLPLTSRLI
                     MDDGLLKGNMQAVILYTSAAFVLVCSDKLLHVCKEAFRAGLSANITYSLYEKAYLHLTR
                     LRMSYFTRTNEAELLNQISMDVGNISRVADSGLFFVIMQAFSMIGGLCGLFMINWKMTV
                     IVLCFLPVKYVAVQYFVRRRKKLIGEMIESSSDFAQWFGEAIGGMKEQRMFGLLANRHQ
                     EFSSRQHRIVGTERKISMLDAWNTASESILIQLLIMVLYIIGSNLIFRLELTVGGIFAF
                     IAYSAYVTTPIFAILNIGYMLAEILPSAIRYYQFLDGEEEETLDLSVLEPISSNRAPDN
                     HIAFHNVSFSYNEDEPVISGLNFMIARGEKVAIIGANGSGKSTVLDLIMRFCQPDQGII
                     TYEGIDIQSYEMDEYRSRIALVSQQVYLFDTTIRDNIRLGSGVSDDVVATSIRDIGLTE
                     FTQSLSDDFRIGSNGSRLSGGQRQKIAMARALVREAPLFILDEATSNLDAASEVNVHQL
                     LETRLSDKTVIVVTHRSEVLKYVQKIILLEAGQSAQIGSHHYFMEHHPGYRKWVSENDE
                     KTNEMIW"
     gene            9744..9929
                     /locus_tag="C1I60_RS07350"
                     /old_locus_tag="C1I60_07395"
     CDS             9744..9929
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04065.1"
                     /locus_tag="C1I60_RS07350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07395"
                     /product="CLI_3235 family bacteriocin precursor"
                     /protein_id="WP_137061148.1"
                     /transl_table=11
                     /translation="MRKLVKRNTNVSDTIEAFGCGCSCYCPCSCYCAGSSTRNSNTQRE
                     SDGSYRRDNGTGIGNY"
     misc_feature    10001..10016
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.79"
                     /tool="antismash"
     gene            10001..11455
                     /gene="ccpM"
                     /locus_tag="C1I60_RS07355"
                     /old_locus_tag="C1I60_07400"
     CDS             10001..11455
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0046500 - S-adenosylmethionine metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="ccpM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308381.1"
                     /locus_tag="C1I60_RS07355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07400"
                     /product="Cys-rich peptide radical SAM maturase CcpM"
                     /protein_id="WP_289306508.1"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.6e-14, bitscore: 46.0, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 6.5e-58, bitscore:
                     188.3, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.8e-13, bitscore: 41.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.9e-13, bitscore: 40.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNICKPFIYTFQTRLHHYLYDVNTNLILRIKEEAYDFLNQHRSFD
                     LNQIEDTPELQQYIGHLLDNGFLSSQRPQIIHHPKTKHLEHMLKYQLKTLTLQVTQNCN
                     LRCSYCVYSGNYDNRGHSSLRMDFETAKKCIDFVIDRSVDSERLDFGFYGGEPLINFLL
                     IQQCVEYIKEKVVHRDIGFHLTTNGTLLNDDILTFLNEHQFVLTVSLDGDKENHDRNRR
                     FAVNGRGSFDTIIANVDKIKESYPDLFEWINFNVVMDTRNDFGCVNDFYANYETFESLY
                     SVRSSYINDAYAKDEVMYRNTFIEQRGYEVFKMMLSKFGRMDESHVSKLIKDYYVQIYF
                     RMFHYRKPSAGMPLEAHHGGPCVPGVQRLFADVNGNLYPCERVSEQSEVVQIGNVDSGF
                     DVDKISQILNVGSITEDACKNCWNFRFCTLCVAVADDLHTLSREMKLNHCAVVKNDVRH
                     TLLDFCMLNELGYDFSDDTILDFENA"
     aSDomain        10004..10381
                     /aSDomain="Other_Sactipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a sactipeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_C1I60_RS07355_Other_Sactipeptide_rSAM
                     _RRE.1"
                     /evalue="7.80E-15"
                     /identifier="RREFam021.1"
                     /label="C1I60_RS07355"
                     /locus_tag="C1I60_RS07355"
                     /protein_end="127"
                     /protein_start="1"
                     /score="46.0"
                     /tool="antismash"
                     /translation="NICKPFIYTFQTRLHHYLYDVNTNLILRIKEEAYDFLNQHRSFDL
                     NQIEDTPELQQYIGHLLDNGFLSSQRPQIIHHPKTKHLEHMLKYQLKTLTLQVTQNCNL
                     RCSYCVYSGNYDNRGHSSLRMD"
     misc_feature    complement(10015..10033)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 24.65"
                     /tool="antismash"
     gene            11470..12591
                     /locus_tag="C1I60_RS07360"
                     /old_locus_tag="C1I60_07405"
     CDS             11470..12591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308382.1"
                     /locus_tag="C1I60_RS07360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07405"
                     /product="TIGR04066 family peptide maturation system
                     protein"
                     /protein_id="WP_137061149.1"
                     /transl_table=11
                     /translation="MDKLLIFPFDSETIALVRNLNLLGSYSEVVLVSFKGSGMIGKDAC
                     VADKGAVTGLTVKPESCLEQELEQCDAILLVRSNFKLDITELYLPLIIKAMKLGKKVMC
                     NFTLPDECMTIIDQYRNQESKLTLKNTFDIFTKGLTAPDPASGIHDFFTPVIFILGLNE
                     RTNKLGLQFAVRQKLEAAGYRISQMTSNGCGELVGAHSFPQFMLESGLTETQKIIMFNR
                     FLKKIEQSEKPDLMLVGIPGGVVPYNNTFTNYFGITSFLASRAVVPDGLICCLHYDEYN
                     TQYLEHVQKYLENRFSSSLLGYALCNNVFDSYSSSTVNMQYSSVDSRFVEEKKREFSDY
                     PVPIMNLSNDDDIGKMADHILNYFSSEQNLIKL"
     gene            12605..12874
                     /locus_tag="C1I60_RS07365"
                     /old_locus_tag="C1I60_07410"
     CDS             12605..12874
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308383.1"
                     /locus_tag="C1I60_RS07365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07410"
                     /product="peptide maturation system acyl carrier-related
                     protein"
                     /protein_id="WP_014279347.1"
                     /transl_table=11
                     /translation="MNGTQDVVELELENIFLKLFEIRLNEVDIGAPLLGSGMRLLPRDL
                     VYLFFEVEKSFAIQISQERISEGCFLTYDRLLETVRECINEQRS"
     misc_feature    complement(12876..12890)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.68"
                     /tool="antismash"
     misc_feature    complement(12877..12890)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.43"
                     /tool="antismash"
     gene            12974..13759
                     /locus_tag="C1I60_RS07370"
                     /old_locus_tag="C1I60_07415"
     CDS             12974..13759
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279348.1"
                     /locus_tag="C1I60_RS07370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07415"
                     /product="muscle M-line assembly protein unc-89
                     Uncoordinated protein 89"
                     /protein_id="WP_137061150.1"
                     /transl_table=11
                     /translation="MNVSIASSHRGSSFTANHNRSGSAQNDRTERNSIARPQNKVLERL
                     MEQKQNLIDRRSDYLSNAVKRGASPDNIKADLEEMDKQIQQMDEAIQKQTLEEQRKALG
                     TDEESKKEIEKGLAEKTEQYNPKTAEEQKQSFFTYTMKGIVSANNELKMAKVTKMAQIT
                     LQSEAKGWENSDPAKSAALREKAEGLNSKILDIAGAVNEHITEALQREQPITREDNQSD
                     EEKQRVEAEGVWTEQELNAYSDSAKGKTEAVGTNVNTVA"
     gene            13920..15530
                     /locus_tag="C1I60_RS07375"
                     /old_locus_tag="C1I60_07420"
     CDS             13920..15530
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013308385.1"
                     /locus_tag="C1I60_RS07375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07420"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_137061151.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2e-17, bitscore:
                     55.2, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSKIHVAIIDDGVTAEVFNTNMLYDIEMVSSLPVHFQTSTSAAQ
                     DKPLEDERQNTYMMNHGTLCAGIVQAYFPNAVISSVKILKQRKGNADQLCAALRWCVKH
                     GVQVANISLGSTDFRDRTLLREVVNEVAAAGLIMVSAAHNGGFLTYPASFSNVIGVECD
                     RSGNLAAGQYRYNLEAAFGGGIEFTAFARHALTDVLGGTVLCPNSNSYAAPLITAQVCM
                     LLQSSKCIYSIELLKNELQEHSCNLVQASRLPVQRYRNPDWIRCAFVFKAGTTTCTVAP
                     YYFQIQREILISSQEAVPVIKAVLVQEHEQQRTTDTLILLGHMDAVALRQVSQLAIQYG
                     KHVVYAGEWQCDIPTMGFFSRQLRLWHGEVGLQRELEKYKEGKSLEIPFVAIYYDGEMD
                     IFYFLHLLKMSFVRDGYHCWVAVDQSRSVLHDMEYICFSRTVNRMEELVCCCNKTASMA
                     HADVVILCLEARQGLDGLRKQNSPDTELELWLQTTEGSEAIRISIVSNNKLLEKRTLQG
                     LNVEAIDALYKYIEYVLVN"
     gene            complement(15557..15799)
                     /locus_tag="C1I60_RS26280"
     CDS             complement(15557..15799)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279350.1"
                     /locus_tag="C1I60_RS26280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_353505562.1"
                     /transl_table=11
                     /translation="MNTLQFLSQDSEARRLYEARQKYLHDEASMIDRAESVGMAKGKIE
                     EKKDIAKNMLSMGMDIAIIAKATGLTEQEIKTIQL"
     gene            complement(15796..16251)
                     /locus_tag="C1I60_RS26285"
                     /old_locus_tag="C1I60_07425"
     CDS             complement(15796..16251)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024194.4"
                     /locus_tag="C1I60_RS26285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07425"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_353505563.1"
                     /transl_table=11
                     /translation="MNPYTDKDDKQSIFDVYAKTAEGKLIDIEMQLFNKYDIEKRTLFY
                     WSKRYAGQLHEGEKYQELKKCVTINILNYSFLPNDEYHNVFHLREDRTGISLIDDIEVY
                     FLELLKLDEQTASFKEGGLINWLLFLKGADPSKWEVLKMNDQDWKRP"
     gene            16413..18176
                     /locus_tag="C1I60_RS07385"
                     /old_locus_tag="C1I60_07430"
     CDS             16413..18176
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014279351.1"
                     /locus_tag="C1I60_RS07385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07430"
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="WP_137061152.1"
                     /transl_table=11
                     /translation="MNDSSFSPQSFEKPNFLVLLVDEERYPAVYENREIKEWSRQNLIT
                     QGLLRSHGLEFHRHYIGSAACSPSRTTLFTGHYPSLHGVTQTDGVAKGAFDSDMFWLDR
                     NTVPTMGDYFRAAGYQTYYKGKWHISDEDIIIPGTHKALPSYHPLTGVPDRRLEGIYEQ
                     ADRLDSFGFSGWIGPEPHGRNPRNSGSSAAVGLSGRDEVYAAETAQLIEALDRRKQHDN
                     HAEPWLVVTSFVNPHDIVLYGAITARLPMFRFEVEPMPDVTPPPTINEWLATKPRCQAS
                     YRDIYPRALQPIMDQPFYRKLYYQLQKNADRQMLKVFEALTRSSFYDNTIVIFTSDHGD
                     LLGAHGNLHQKFYCAYEEIVHVPLVIHNQHLFPQYKSEHTLTNHVDLLPTMLGLANVDI
                     TAIQSRLQNSFSEARPLVGRDLTPVIRGQNQGEIVDQPVYFMTDDDVTRGQRQINILGE
                     AYPSVVQPNHIETVITPLQREGVKELWKFTRYFDSTQFWSQPGVKDVTMRPVGEHTCGQ
                     YSQWATQVKTQPERDEYELYNLTSDPLETCNLAHPAFATQQSRSVQQQMMRLLEEQRKQ
                     KRLYPAQSGVR"
     gene            complement(18433..19539)
                     /locus_tag="C1I60_RS07390"
                     /old_locus_tag="C1I60_07435"
     CDS             complement(18433..19539)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007432397.1"
                     /locus_tag="C1I60_RS07390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07435"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_137061153.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 1.3e-24, bitscore:
                     79.1, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 8.4e-24,
                     bitscore: 75.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKMKVGIIGCGKISGIYMENCQRFDILELSAVADLDQGRAKEQA
                     AAYNVPNVYSVDEILADPEIELIINLTIPAVHADVSLRALETGKHVYVEKPLAVTREQG
                     QAVLELARRKGLLIGCAPETFFGSGIQTALKLIEEGVIGRPVAATAFMMSRGHEHWHPD
                     PEFYYAMGGGPMFDMGPYYLTALVQLLGPIATISGMTGKALDQRSITSEKKRGQTIPVD
                     IPTHVAGLLRFEQGAVGTLITSFDIFGGSSLPPIEVYGTHGTLQVPDPNTFGGPVRYRL
                     QGEQEWTEAPLLPGYQENTRGIGVADMAYAVRSGRPHRASGELAYHVLEAMWAFHDSSD
                     EQTFYPMQSTCLRPAALPEGLPLYTLDA"
     gene            complement(19613..20341)
                     /locus_tag="C1I60_RS07395"
                     /old_locus_tag="C1I60_07440"
     CDS             complement(19613..20341)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013371325.1"
                     /locus_tag="C1I60_RS07395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="C1I60_07440"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_137061154.1"
                     /transl_table=11
                     /translation="MSKALIVWGGWDGHEPEQVAAIFERILKEERFEVEVSNNLEAYQD
                     AEKLLGLDLIVPLWTMGQIEQELVNHVSAAVQSGVGLAGCHGGMCDAFRNNVDWQFMTG
                     GQWVAHPGNDGVEYMVNMKRGSSPLLDHIEDFQVKSEQYYLHVDPAVEVLATTRFPVVP
                     GPHSANGPVDMPVVWTKCWGNGRVFYNSLGHHADIIEMPQVTEMMRSGFLWAAAGKQTA
                     AARGGSLADAYTGMADNQQR"
ORIGIN
        1 cacgctgacc ggatgttttt ggaatattga gtgcattacg cgcgtttgtg atcattttat
       61 tgaaattcgt gttgccaacc acaagctggg aattgaacac cccgtacata taggaggtgg
      121 ttgtaatggt ttcttcctta cctcccgcgt aatgcccgcc cattaaaata tgcccatggg
      181 gacgctctac acgaagctct ttggatttga gtacgacatg ttcatagctg tccgtgaaaa
      241 aggagagcaa cgtgtcgccg tcccgttctt cttcctgccg tttcgggaag agctgatcca
      301 actcggctgc ggtcatatcc agcgtgcgca gcggctcccc gatgttctgg gctggagcca
      361 cccgcccagt ttggagatga cttgtgacgt tctctgggat ggcggttccg gaagcagttt
      421 ccataatcgt cgctacttct tcgcgtgctt tcgtcaccag ttcctggtac tccagctttg
      481 taacggctgt cggatgattc ggctggaaca gaccgtaaaa ggtaaagcgt gcatccccgg
      541 cgagctttac ccgctcggat tgcagcgccg tataagcaaa ttcgtactgg tatacttcat
      601 tagcgagcga atcgcggcgc agtgcttccg gctcgttcgt ttctttgtac gaaagcccaa
      661 agaattgaaa tccgtccgtc gaataaccga cggtgcgggt caacgagcct tgctggatgt
      721 aagggaacgc ttgactttgc ggctggtttt gacgggagca gaccgtatag cctctttgtt
      781 cgtcatggta gacggtatgg tcgatatatt gagacagata agcttcatta ctgcgtacag
      841 ccgctgtatc cgcaatgccg atatcctgac cgtacacgat atcagcttcc acgtcatcgc
      901 cctgtagagt tacatcccag aaccataccc cgagaccgct tagtgtgaat gtcacctgat
      961 agccgacacc tgatgtaaat ccttcccaaa taatttgttg atccgtttgt cgtactactc
     1021 cgggtgatcg gactcccagc aggggagtaa tgctgacgcc ggacggacgg tacagtcgca
     1081 ggtacaggtt gttcagggaa ccgtcgacag aattggtcag cagttgattg atcatggttg
     1141 agccatgggc gattttatat aaatcaccgc tgctcaagaa ggtgaaggac aggtctccaa
     1201 cccgtagcaa aatattttga tccagacttg tattcatcaa aggttacgcc tcactttcct
     1261 gtttctttca ctaaacgaaa acgtccttca gtagtatctc ggctgttagg tcctgtaaag
     1321 acggcgaatt caccgctgtc actatcaaag ctcaggtctg catggtgata gcgcagttga
     1381 gactcgatca atgaaaattc cacttcccgg ctttcgcctg aggcaagcag aaccttgcgg
     1441 aaatctttca gctctttcat cgggcgaacc gtatctccgc tgatatcacg gacatagaat
     1501 tgaaccgttt cctcgacagg acgtgttcct gtgttcgtta cccgtacctt cacggtcagt
     1561 gcttgaccgg gagtgagggt gtcgctggaa agctgtacgc tatcataggc tactttcgta
     1621 taactcaagc catagccaaa cgggaataaa ggttcgttcg gtacgtccag gtattgggag
     1681 acgtatcgtt cctttgtatt tggatccagc tgaggacgtc ctgtattaaa atgattatag
     1741 tacacaggca cctgccccac cgattgcggg aaggacattg tcagacggcc cgttggttca
     1801 gcatcgccgt acagtaggtc ggcaatagcc gcgccgcctt caccgccggg gaaccaggct
     1861 tccagtacgg cgtctgcttc ttcaataaca ccgtgcagat ccagtgggcg accgttgaac
     1921 agcacggcta ccataggctt gttcagtgtt ttcaggcgtt tcactagctc cagttgggct
     1981 tgtggcaggc gaatatccga gcggctgccc gcttcaccac tcatatccga acgctcgccg
     2041 agcgccagta cgatgacctc tgcttggctg gcagcttgca gcgcttctgc atattgttct
     2101 tcagatattt cgtctataga gcatccagtc gctaccgaga gcagcgagga ggatattttc
     2161 gatttgaagc cgtcaatgac ttgaacagcc tcttcttgcg aaccgctcca cgaccaagag
     2221 ccaagaatat caccgctctc tgcaaaaggc ccgatcagtg cgatatgctg actgcgattc
     2281 agtggaagaa tggaatcgtt tttgagcagt acgcatgatt ggatcgccaa ttccttggca
     2341 accgcacggt gagcttcgca gaacacgact tcacgttccc gctcagggtc tgcgccgcgc
     2401 agcggattat cgaacaagcc cagcttttgc ttgagcttca atacgcgcat gaccgcttca
     2461 tcgacgagcg cttcatccag ttgcccgctg cgaaccagct caggcaggtg cccattatag
     2521 caggaggtca tcatttcaat gtctacgcct gccagcagtg ctttctgtgc tgcctcacgc
     2581 tcatcctcgg caatgccgtg gggaataagc tccttgatgg cggcccaatc cgagatgagt
     2641 acaccgtcaa agccccactc gtcacgaagc aaatcgcgca tcaggcgctt gttgcccgtt
     2701 gcagctacac cctctacggt attgaaggag gtcatcacca tttcacagcc ttcatctagc
     2761 gcagctttgt aggaggggag ataatactct cgcaactgcc atgcggacag atcgacggta
     2821 ttgtaatccc gtccgccttc gcctgctccg tatgcggcaa aatgcttcac gcacgccgcc
     2881 acccggtctg tatcgttcgt caggtccttg ccttgaaagc cgcgtacgaa agcacgggca
     2941 aatacactgt tgaggtaagg gtcttcccct gtagattcca ttacacggcc ccagcgcggg
     3001 tcacgtacca agtccaccat cggagcaaag gtgacatgaa caccggatac agaagcttct
     3061 ctggcagcaa tggtagcgct ctcttctgcg agctgcacat tccatgaaca gccaatagcc
     3121 agcggtatgg gaaaaatcgt tttgaagcca tgtacaatgt ctgccataat tagaagcgga
     3181 atacccagac ggtttttact tagatgtgct tgttgaactc gaatagcttc ttcggctcct
     3241 gcgatgccaa gcaccgatcc gacgttacgg accgtttctt ctgtgatccc cagagatgcc
     3301 ataggtccgg taatttggcc gtccgtttcc gcatcctcaa aaaaggctcc cacgagctgg
     3361 agcagttgat cgactttttc ttcaagcgtc atattttgca gataggaatt cagttgttgt
     3421 tccatcatac aatcctccgt aagctgctat ggttgcagct ttctttttca gatccatgag
     3481 attttttggt gaagactgat tcaaagaagc gacgaatagg ctaatacttt gcataaatgc
     3541 ttagtatcct gtcgtattat taatcgaaac gtttctattg ttgaactcag ttggattata
     3601 tacgctttca aatagagagt caaatcgaaa aagaaggtta ttttactaag aaaataacga
     3661 tttatagatg aaacgaaaga aaattgggca taattctaga cgaataaaaa ataatatccc
     3721 tattgaatac ggtttcaatt tgttttataa tgactatcga aacgtttcta ttgatgggta
     3781 tggtccttac actttccaca tattttctat atcgtcaggc tttatttggc tttaaacact
     3841 gtatacttta acgtgtgtaa tcgaatcggg tatcatattt gaatgatcgg tgagccggtc
     3901 atctcgggag gaatttatat gatgaaaaga acgttaggga tcgttttggc aagcacctta
     3961 ttactggggg gcgcgttggc aggctgttca tccaaggatg aatcatccgg caaggatgcg
     4021 aatggaaaaa cgacgattac cctatggggc atgggggcgg aaggtaagtt gctgcctgag
     4081 attgcaaagg attttgaaaa ggaaaatcct gatattcatg tagatgtgca ggcactgcct
     4141 tgggataatg ctcacgataa gctgctgaca gcagttgctt ccaaatccgg tccggatgtg
     4201 gttcagttgg gtacatcatg ggttccggag cttgcatctg cgggtgcatt gacggacatc
     4261 accccttata tcagcaaata tcctgagctg gaatcaaaga atttcttctc tggtgctgtg
     4321 gatacggcaa aatttgaggg aaaacctgta ggcgttcctt ggtataccga aacgaaagtt
     4381 ttgttctacc gttcagatct attgaagcaa gttggatata atgaagcacc taaaacgtgg
     4441 gaagaacttt cggatgctgc tcaaaagctg gcagcgcgtg gcaaagggaa atatggtatt
     4501 gccattaatg cgaaggagca gtctctgggc tttatgttcg ctcttcagaa cggctccaag
     4561 ctgatcgatg agcagggcaa tccgctgttc aaccagccac cgtttgtaga agctgtgaag
     4621 tatttgaaca cctttttcca aaacggctcc aatgccctag atcttgggat agattccgtt
     4681 cagggattgc aaggtgatgg tatcgttcct atgtttatca gcggtccctt catgattaga
     4741 gaaatcaaga gcaaggcacc tgagctggat ggaaaatgga atatagccga gcttcctggc
     4801 aaagtaaaca acctgtctgt tttgggcggg tcgaaccttt cgattatgca gtttagcaag
     4861 cacccggagg aatcggccaa attcttggct tacatgagta aaccggaaac gcagttgaaa
     4921 tggatggagc tgtccagtac cttgcctgcc gctaccaagt catgggaaga tgcaaaactg
     4981 aagaatgatc cgatgcttca aacgattcgt aaacagctcg atcattccgc agcattaccg
     5041 caactggcag catgggaaga ggtttctcaa caattcatca agagcttcga acgcatttac
     5101 cgtggtcaag ccgacgtaca gaaggaaatg gatgatttta accagcaagc tgcaagtatt
     5161 atgaaaaaat aatgatccgt atccgtcatt gtcaaaggga gtgaaggcat gaaaggaagc
     5221 tcgcagaagc ttgcgccata cttgtttatc ggtccctcca ttattctgct gacgctgttt
     5281 tcgttgttgc cgattttact ggcactcgtg atcagcttca cagatatgga tctgtcagga
     5341 ctcgttaatt atgataatat tcgctttata ggactggaaa attacaagaa tgtgctaata
     5401 gacccttctt ttctaaagtc cattgggaac actctatttt tcgtcatcat cggggttcct
     5461 ttagtgctat tgttttcact cagcattgca atcctgatta acatgggtaa atcacgtgct
     5521 ttcaaagttt tccgcgtggt gttctatctg ccgtccgtaa cgaacgtggt ggcggtagcg
     5581 gtggtctgga gttatttgta taatccgacc ctcgggcttt tcaactatgt actgggcatg
     5641 atgaatctgg atcctgttcc ttggctgacc gatcctacga tggcgaagat atcgcttatt
     5701 ttattggctg tttggcgggg aataggctta aatatgatta ttttcattgc tgccattaaa
     5761 gggattccgg gttcttacta tgaggcggct cagcttgacg gggccaacac atggcaacaa
     5821 attcgttata ttacccttcc gcagctccgc tacgctatct tcttcgtatc cattacgacg
     5881 atgatcggct ggctgcaatt tttcgaggaa ccgttcgtca tgaccaaagg gaaaccgctt
     5941 gacggcacac tatcagcatc cctgtttata tacaataacg gtttccaatt tagtaaattc
     6001 ggttatgccg cggcgggatc gttcattctg ttctttgcga tcatcgcggt gacgctgatt
     6061 cagttccgtt tgcaaaataa agcggagtcc tgatagagag aggtgatgaa cgtgaaaaca
     6121 gctgttcagc aagcccgcgc caattcgcgc agtggagaaa aaacatttca atggttcgtg
     6181 gcgattctcc tgaccgtggg aggtctgttg atggtgctgc cttttgcgtg gatgatttta
     6241 tcctccttta agacggagag cgaggtaacc caaattcctc caaccatctg gccgcagcat
     6301 ttcacattgg acaattttaa aacactattt gatagcatgg cttttggcac ctatctgact
     6361 aatacactgg tgattgtatt agcttccttt tttggattat tcctgaacgc catggcaggc
     6421 tacggcttcg ccaaattcaa atttaaaggt aaaggtttcc tgttctattt ggtgctggcc
     6481 acgatgatgg ttccggggca ggtgacgatg attcctgtgt atttgatttt gaaccagatg
     6541 ggattaacca acaccatgat ggggattgta cttcctggct tggtaggtgc cttcgccatc
     6601 ttcctgttcc gacagtttat gtccgatatt ccggaagaac tgctggaggc aacgcgcctt
     6661 gatggtgcag gggagtttcg tactttcctg caaatcgtac tgcctatctc aacaccgatt
     6721 ttggccgtac aggccattct gacctttatc ggcggttgga acagcttcct gtggccgctc
     6781 attattgcga acgatgagaa gctgtatacg ttgtccgtgg gactatcgtt gctcaaaggc
     6841 caaaatgaga gccagttcgc gctccagatg gcaggctcga ccttcatggt cgtaccgatc
     6901 atgatcatat tcattgtttt ccaaaagtat attatcgaaa attatacgat ttcgggcatt
     6961 aagtagtagt tgtagcggtg agttataggc tacacatagc aacggcggag tttcttggtt
     7021 taataccgag gaactccgcc gttttgttgt gtcatataaa atctggtttc ttgtttggtt
     7081 catccgaagt gctggtatgt ttgcacaggg gtctgtattt acatatgagt caaataatat
     7141 tgatgtgaca gggtgcggag tgtttttcta agcctgtaaa tccgtgtagt ggtagctgta
     7201 atagaaatat tatatttggt agcaaggatc gaaatggaca tgttctgcaa aaaataatcc
     7261 tgatatagct catattcttt cttcgagagt tgcgtcagga tgctgtttat aatctgatca
     7321 atatcttgaa acctgctttt ctcccaatcc tcttctaccg aaattgaaag actgcaagcc
     7381 tcatgttcaa acatagtctc atgctttttt tgtgtgtagt agcgtcttaa tgatttatgt
     7441 acaaagtgtt tggccgtgag gtatagccac cctttcacat tgggatgaag tttgagctta
     7501 catagctgtt gtcttgctgt caaaaaagta tcttgtgtac actcctctgc tatgcatcta
     7561 aattgcaatt catttttgag cagatgtatg cagaaacggt acacgtcatc cagataaagt
     7621 tcacatattt gattatagaa acaattgtac tgtctagtgc attgatcccc ttcacagcag
     7681 tctgtaacca tcgttgtcgg catgttcaag cctcctttag acggatgaaa gatcataaac
     7741 gttataaaac tcatgaccat catatacaat atttggatgt attggagata acaaaagtca
     7801 cagcttcatt tcgtgagtat ggaattaaag gaagagctat atgttcagat cgggtgatta
     7861 tatcgtcaaa atggtattag taaaggagag ggaacaagag ggaaagaggg agagggatga
     7921 aagaatcaat tgtgttcaaa cgattggcgg gattatttag gacgcacttg aagtccgtca
     7981 ctattattct tacgtgtcta attatatcgg cgggtatgaa catgctactg cctttaacaa
     8041 gcagactcat tatggatgac ggccttttaa aaggaaatat gcaggctgta atcctgtaca
     8101 cgtctgctgc atttgtgctg gtatgctcag acaagctatt gcatgtatgc aaggaagcat
     8161 tcagggcggg tttaagtgcc aatataacgt attcactata tgagaaggcc taccttcatt
     8221 tgacaaggct ccgaatgagt tattttaccc gtacgaacga agcagaactg ctcaatcaaa
     8281 tcagtatgga tgtaggtaat atatcaaggg ttgcagacag cggacttttt ttcgtcatca
     8341 tgcaggcgtt tagtatgatt ggcggtttat gtggtttgtt catgattaat tggaaaatga
     8401 cagtcattgt gctttgcttt ttgccagtca agtatgttgc tgtacagtat tttgtcaggc
     8461 gcagaaaaaa gctgatagga gaaatgatag aaagtagcag tgattttgcg cagtggtttg
     8521 gagaggccat cggaggaatg aaggagcagc ggatgttcgg tctgcttgct aacaggcatc
     8581 aggaattctc atcgaggcag catcgtatcg tcggtacgga acgaaaaata tcgatgctgg
     8641 atgcatggaa tacggcctcg gaatctatct tgattcaatt gctgattatg gtgctgtata
     8701 tcattggatc caatcttata tttcggctag agcttaccgt tggcggtatt tttgcgttta
     8761 ttgcgtacag tgcttatgtc acaacgccta ttttcgccat cttaaatata ggttacatgc
     8821 tggctgagat tctcccgtct gccattcgct actatcaatt tctggatggg gaagaggagg
     8881 aaacgttgga tttgtctgtt ttagagccta tttcttctaa tcgggcaccg gacaaccaca
     8941 ttgcgtttca taatgtttcg ttttcatata acgaagatga gcctgttata agtggattga
     9001 actttatgat tgctagaggg gagaaggttg caatcatagg agccaatgga tcgggcaaat
     9061 ccaccgttct tgatctcatt atgcgttttt gccaacccga tcaagggatc atcacttatg
     9121 agggcattga tattcaaagc tacgaaatgg atgaatatcg tagccggata gctttggtca
     9181 gccagcaagt gtatttattc gatactacga ttcgtgacaa tattcggtta ggctcaggtg
     9241 tcagtgacga cgtagttgct acaagtatta gagacattgg attaactgaa ttcacacaga
     9301 gtctgtcaga cgattttcgt atcgggtcta atggctccag actgtcaggc ggtcaaagac
     9361 agaagattgc catggcccgg gcattggtta gggaggcacc gctatttatt ctggatgagg
     9421 cgacctctaa tctggatgca gcttccgagg tgaatgtcca tcaattgttg gagacacgtt
     9481 tgagtgacaa gacggtaatc gttgtcacac atcgtagcga ggtgttgaag tatgttcaaa
     9541 aaattatttt gctggaagct ggacagtcag cccaaattgg atcacatcac tactttatgg
     9601 agcatcatcc aggctacaga aaatgggttt cggagaatga tgagaaaaca aatgaaatga
     9661 tttggtgatt ttatctctta tctgggatta gtatagatga acaccgcttt aaaccatttt
     9721 gtaaaagaaa ggagaggttt agcatgcgta agcttgtgaa acgaaacaca aatgtcagtg
     9781 atacgattga ggcatttggc tgcggatgtt cctgctactg tccttgttcc tgttattgtg
     9841 caggcagctc gaccagaaac tccaacaccc aaagagaaag tgatggctcc tatcgaagag
     9901 acaatggaac aggcatcggc aattattaag ctattcatca acttggggga gcctgtattt
     9961 taggctcttc caccacttta aattagagta ggtgtgaatg atgaacattt gtaaaccgtt
    10021 tatatataca tttcagacta gactgcatca ttatctgtat gatgtgaata caaacctgat
    10081 tttgcggatt aaggaggagg cgtatgactt tttgaatcag catcgcagct ttgatctgaa
    10141 tcaaatagaa gatacgccag agttgcaaca gtatattgga catttactgg ataacggttt
    10201 tttatcttca cagcgtccgc agatcattca ccacccgaag accaaacatt tggagcatat
    10261 gttaaagtac cagcttaaga cgctcaccct gcaagtaacg caaaattgca atctcaggtg
    10321 ctcctactgt gtctattctg gaaattatga caatcgtggg cattccagct tgcggatgga
    10381 ttttgaaacg gcgaaaaagt gcattgactt tgtaatcgac aggtcagtgg acagtgaacg
    10441 gctcgatttt ggcttttatg ggggagagcc actgatcaat ttcctgctca tccagcaatg
    10501 tgttgaatat atcaaggaaa aagtggtgca cagggatatc ggttttcatc tgacgaccaa
    10561 cggtacattg cttaatgacg atattttgac attcttgaat gagcaccaat ttgtccttac
    10621 agtcagcctg gacggagaca aggaaaatca tgacagaaac agacggttcg ccgttaacgg
    10681 acgaggatca ttcgatacga ttattgcaaa tgtagataaa atcaaggaga gctaccccga
    10741 tctgtttgag tggattaatt ttaatgtcgt tatggatacc cgcaatgatt ttggctgtgt
    10801 gaatgatttc tacgctaatt atgaaacgtt cgagagtttg tatagcgtta gatcctcata
    10861 cattaacgat gcttatgcaa aggatgaagt aatgtatagg aataccttta ttgaacaacg
    10921 aggctatgaa gtatttaaaa tgatgctgtc taaattcggg agaatggatg aaagccatgt
    10981 ctccaagctg attaaggact attatgttca gatatacttc cggatgtttc attacagaaa
    11041 gccgtctgca ggcatgccac tggaggcgca tcatggggga ccgtgcgtgc cgggtgtcca
    11101 acgcctgttt gctgatgtaa atggaaacct gtatccgtgt gagcgggtaa gcgagcagtc
    11161 tgaggtggtc cagattggca atgtagattc gggctttgat gtggataaaa tcagtcaaat
    11221 attaaacgtt ggctccatta cggaagatgc ctgtaaaaat tgctggaatt tccgcttctg
    11281 tacgctatgc gtcgctgtgg cagacgattt gcacacatta tccagagaaa tgaagctgaa
    11341 ccactgtgct gtagtgaaaa atgatgtaag acatacttta ctggactttt gcatgctgaa
    11401 tgagcttgga tacgattttt ctgatgatac gatccttgat tttgaaaatg catgagagga
    11461 gttcacaata tggataagct gctcattttt ccatttgata gtgagacgat agctcttgtg
    11521 agaaatttga atttattggg tagttacagc gaggtggtac ttgtttcctt taaggggtcg
    11581 ggcatgatcg ggaaggatgc ctgtgtagcc gataagggag cagttacggg gctcacggtg
    11641 aaaccggagt cttgtctgga gcaagagctg gagcagtgcg atgccatttt gttggtgcgt
    11701 tcgaatttta aactggacat cacggagctc tatctgccac tgattattaa ggccatgaag
    11761 ctcgggaaaa aagtaatgtg taatttcact ttaccggatg aatgcatgac tatcatcgat
    11821 cagtatcgga atcaagaaag caagctcacg ttaaaaaata cattcgatat atttaccaag
    11881 ggacttactg ccccggaccc agcttccggt attcacgatt tctttacgcc agtcattttt
    11941 atactgggct taaatgagcg gacaaacaag cttggactcc agtttgctgt tcgacagaag
    12001 cttgaggcgg caggatatcg gatttcccag atgacgtcga acgggtgcgg ggaactggtc
    12061 ggtgctcatt cctttcccca atttatgctg gagagtgggc tgacggagac ccagaagatt
    12121 attatgttca atcgttttct gaaaaaaata gagcaaagcg agaagcctga tcttatgctc
    12181 gtaggcattc cgggaggggt agtaccatat aacaatacct tcacgaatta ttttggtatt
    12241 acatcttttc tggcatcaag ggctgtcgta cctgacggtc tgatctgctg tcttcattat
    12301 gatgagtaca acactcagta tctggagcat gtgcaaaagt atcttgaaaa tcgtttttct
    12361 tcatctttat tgggatatgc cttgtgtaac aatgtatttg acagctattc ttcctctact
    12421 gtgaatatgc aatattcttc tgtggatagc cgatttgtcg aagagaagaa gcgggagttt
    12481 tctgattatc ctgtacccat aatgaacctg tccaatgatg acgacatcgg aaagatggct
    12541 gatcatattt tgaattattt ttcaagtgag cagaatctta ttaagttgta acggaggaga
    12601 gaacatgaat ggaacgcagg atgttgtgga gttggaactg gaaaatatct ttttgaaact
    12661 ttttgaaatc agactaaatg aggtagacat cggcgctcca ctgcttggtt cgggaatgag
    12721 actacttccg cgtgatttgg tatacctctt ctttgaagta gaaaaaagct ttgctattca
    12781 gatttcacag gaacgaatat cggagggctg tttccttaca tatgatcgtt tgctggagac
    12841 tgtaagggaa tgtataaacg aacagaggag ttgaatattt tgtgaaaaat ctgaataaat
    12901 agtagacaat ggccgatata ataatagaaa taactttttt tgggatataa atatatgaat
    12961 tggaggtttg gggatgaatg tatccattgc gtcatctcat cgagggtcgt cttttacggc
    13021 aaatcacaat cgttcgggat ccgctcagaa tgatcgaaca gaaaggaata gtatagcaag
    13081 gccgcagaac aaggtgcttg aacgcctgat ggagcaaaaa caaaatctga ttgataggcg
    13141 ttctgattac ttgagtaatg cggtcaagcg aggagccagt ccagataata taaaagctga
    13201 ccttgaggaa atggataagc agattcaaca aatggacgag gctattcaga aacagacgct
    13261 tgaagaacaa cgcaaggctt taggtacaga tgaggagagc aaaaaagaga ttgaaaaggg
    13321 attggcagag aaaacagagc aatataatcc caagacagct gaagagcaaa aacagagttt
    13381 tttcacatac acgatgaagg gtattgtctc tgcaaacaat gagctgaaga tggcgaaagt
    13441 aaccaaaatg gctcaaatca cattgcaaag cgaggcgaag gggtgggaga acagcgaccc
    13501 tgcaaaatct gcggccttgc gagagaaggc agaggggctt aatagcaaaa tcctggatat
    13561 agccggagct gtcaatgagc atattaccga agcgctgcaa agggaacaac cgattacccg
    13621 tgaagataat caaagtgatg aggaaaaaca gcgtgtagag gcagagggag tgtggactga
    13681 gcaagagctc aatgcttact cggattcggc taaaggaaag acagaagcgg tcggcacgaa
    13741 tgttaatact gtagcttaac acattcctgt cttccctaat ttctgcttga tagactagga
    13801 aggcaaagta gcggcggtcg tttcttggca ctgtagtgat tagtggcaat cctcaaaata
    13861 gtttccgtgg tgatacacgg aaactatttt attatcgggg gaaacgggga gtgggaagag
    13921 tgaattctaa gattcatgta gcgattattg acgacggagt tactgcggaa gtcttcaata
    13981 caaatatgtt gtatgatatt gaaatggtct cttcattacc agttcatttt caaacatcca
    14041 caagtgctgc ccaagacaag cccctggaag acgaacgaca gaatacgtac atgatgaacc
    14101 atgggacatt atgtgcaggt attgtacaag cctattttcc gaatgcagtg ataagtagtg
    14161 ttaaaatatt gaaacaaagg aaaggaaatg ctgatcaact ttgcgctgcc ctgcgctggt
    14221 gtgtaaaaca cggggtacag gtagccaata tcagtctggg aagtaccgat tttcgggatc
    14281 gtaccttatt gcgggaagtg gtgaatgaag ttgcggccgc agggcttatt atggtaagtg
    14341 ccgcacacaa tggcggtttt ctcacttatc ctgcttcctt cagcaatgtg attggagtag
    14401 aatgtgaccg aagcgggaac cttgctgcag gtcaatacag gtataacctt gaggcggcct
    14461 tcggtggtgg aattgaattc acggcttttg ctagacatgc ccttacagac gtgttaggag
    14521 ggacagtgtt gtgccctaac agcaacagct atgcagcccc gctaatcacg gcacaggtat
    14581 gtatgttatt gcagagctct aagtgtattt attctataga gttgcttaag aacgaattgc
    14641 aggaacatag ctgtaatctg gtgcaagcct cccgtttacc agtgcaacgg tacagaaatc
    14701 cagattggat tcggtgtgcg tttgtattta aagcaggtac tactacctgt acagtggcac
    14761 cgtattattt tcagattcaa cgtgaaattc tgatctcctc tcaagaggct gttcctgtga
    14821 tcaaagcggt gctcgtgcag gagcatgagc aacagcggac aaccgatacc ctcattttat
    14881 tggggcacat ggatgcggtt gcccttcggc aagtgagtca attggctatt cagtacggta
    14941 agcatgtggt ttatgcaggt gaatggcagt gcgatatccc cacgatgggc tttttctccc
    15001 gtcaattgcg cttatggcat ggagaggtcg gcctacagag agaactggag aagtataagg
    15061 aaggaaagtc tcttgaaatt ccgtttgtcg ctatttatta tgacggggaa atggacatat
    15121 tttattttct gcatttgctg aaaatgtctt ttgtccggga tggatatcat tgttgggttg
    15181 cagtggatca gtccagatct gtattgcatg atatggaata catttgcttt tctcgtactg
    15241 taaatagaat ggaggagctt gtatgctgtt gtaataagac cgcctccatg gctcatgcgg
    15301 atgttgttat tctttgtctg gaggcccgtc agggtttgga tgggttgagg aaacagaact
    15361 caccggatac agagctggag ctttggttgc aaacaactga aggatcagaa gctatccgaa
    15421 tttctatagt aagtaataat aaacttttgg agaaaaggac gctccaaggt ttaaatgtgg
    15481 aggctataga cgctctgtat aaatatatag agtatgtgct ggtcaattaa cattcctatt
    15541 atttgggtaa tattttctat aattgaatcg ttttaatttc ttgttcagtt aatccggtag
    15601 cctttgcaat gatagctatg tccataccca tggaaagcat atttttggcg atatcctttt
    15661 tctcttctat ttttcctttc gccataccga cggattctgc tctatcgatc atggaagctt
    15721 catcgtgcag gtatttctgc cgggcttcat acagacgtct tgcttctgaa tcctgactca
    15781 agaattgcag cgtgttcatg gccttttcca atcctggtcg ttcattttta aaacctccca
    15841 tttggatgga tctgcgcctt taagaaacaa cagccagttg ataagccctc cttctttgaa
    15901 ggatgcggtt tgctcatcca gcttcagcag ttccagaaaa tatacttcaa tatcatcaat
    15961 aagtgatatc cctgtgcggt cctcgcgtaa atgaaacaca ttgtggtatt catcgttagg
    16021 taaaaaagaa tagttgagga tgttaatggt cacacatttt tttagttcct ggtatttttc
    16081 gccctcatga agctgtcccg cgtatcgctt actccaatag aacaacgtcc gcttctcaat
    16141 atcgtatttg ttgaaaagct gcatttcgat atcaattagt ttgccctctg cggtcttggc
    16201 atagacatca aaaatagact gcttgtcgtc cttatccgta tagggattca ttaaaataat
    16261 ttcggttaat tgagcttctc cagctcccgt ttagtattaa ttatatcatc ttttttaaga
    16321 tatcagattg tctgaacttc ttttccgaat gatactgttt catcatttca ctacatattc
    16381 ttagggtaaa aactaacctg ggatgtgtat acatgaatga tagctcattt tcaccccaat
    16441 cctttgaaaa acctaatttc ctggtactcc ttgtggatga ggaacggtat ccagcggttt
    16501 atgaaaaccg ggaaatcaaa gaatggagca gacaaaatct tattacgcaa ggactcttga
    16561 ggtctcacgg actggagttt cacaggcatt atattggaag tgctgcatgc agccccagca
    16621 gaacaacctt gttcactggt cattatccgt cactccatgg cgtcactcag acagacggag
    16681 tggccaaggg ggcattcgac tccgatatgt tctggctgga tagaaatacg gtgcctacga
    16741 tgggggatta ttttcgcgca gccggatacc aaacgtacta taaaggaaaa tggcatatat
    16801 ccgatgagga tattatcatc ccgggtacgc acaaagccct tcccagctat catccgctga
    16861 cgggggtacc cgacagaaga ctggaaggca tatatgagca agccgaccgc ttggatagct
    16921 ttggattttc cgggtggatc ggtccagagc cgcatgggag aaacccacga aattctggtt
    16981 cctccgccgc tgttggttta agcgggcgag atgaggtgta cgccgcagaa accgcccagc
    17041 taatcgaagc ccttgaccgt cggaaacaac atgacaacca tgcagagcct tggttagtcg
    17101 taacttcatt tgtgaacccg catgatattg ttttatatgg tgctattact gcgcgattgc
    17161 ccatgtttcg atttgaggtg gaaccgatgc cagatgtcac tccccctccg acaatcaacg
    17221 aatggctggc tacaaagcca cgctgtcagg caagctacag ggatatttac cctagagcgt
    17281 tacagcccat tatggatcag cccttttatc gaaagcttta ctaccagttg caaaaaaatg
    17341 cagaccgtca gatgcttaag gtatttgaag cactgacccg ttcttctttt tacgataata
    17401 ccattgtgat ttttacatcc gatcatggag atttgctagg cgctcacggc aatcttcatc
    17461 aaaaatttta ctgtgcttat gaagagattg tgcatgtgcc tttggttatc cataaccaac
    17521 atctgtttcc tcaatataaa agcgagcata ccctgacaaa ccacgtggat ctcctgccta
    17581 cgatgcttgg actggcgaat gttgacatca ctgcaatcca gagccgcctg caaaacagct
    17641 ttagcgaagc ccgccccttg gtgggacgtg atcttactcc tgttatccgc ggacagaacc
    17701 agggggagat agttgaccag ccggtttatt ttatgaccga cgatgatgtg acccgaggac
    17761 agcggcagat caatatactg ggagaggcat atccgtctgt tgttcagccc aatcatatcg
    17821 agactgtcat tacgcccctg caaagagagg gtgtaaagga gctgtggaag tttacccgct
    17881 attttgacag tactcaattc tggagccaac cgggggtgaa ggatgttact atgcgacccg
    17941 tgggcgagca tacatgcgga caatattctc aatgggctac acaggtcaaa acgcaaccgg
    18001 aacgtgacga atatgaattg tataacctga ccagcgaccc tttggaaaca tgtaaccttg
    18061 ctcatccagc atttgcaacg cagcagagca gaagcgttca gcaacagatg atgcgcttac
    18121 tggaggaaca acgtaaacaa aaacgtttat atcccgctca atcaggtgtg aggtgaaaaa
    18181 caacgctttt tccctcttcc gggtcatcgg aaacagcttg atgctctcta ttaaacgcga
    18241 ttcggtcgat aattatgtat tcggttacaa tgttaccata cgaacagcgg agcttctctt
    18301 tgaaggaggg gctccgcttt ttcgggttca catggacatg ttgtgaaaaa tccaaaaaaa
    18361 caacttttgc ttacagcctc accagtcttg taaatctggc ctgctgccga ttagcagcag
    18421 gctgacattt ttttacgcat ccaacgtata caagggcagg ccttccggca aagctgccgg
    18481 gcgcaggcat gtgctctgca tcggatagaa tgtctgctca tcggaggaat catggaacgc
    18541 ccacatcgcc tccaacacat ggtaggccag ttcaccgctg gcgcggtgag gccgtccgct
    18601 gcggacagca taggccatat cggcaacgcc gatgccccgt gtattctcct ggtagcccgg
    18661 cagcagcggc gcctctgtcc attcctgctc gccctgcagc ctgtagcgaa ccggccctcc
    18721 gaatgtgttc gggtcaggca cctgcagcgt gccatgagta ccatatacct cgatcggtgg
    18781 cagggagctt ccaccaaaga tgtcaaagct ggtaatcaac gtgccgacag ccccctgctc
    18841 aaagcgtagc aatccagcca catgggtcgg aatgtcgacc gggatggtct ggcctctctt
    18901 tttctcgctt gtaatacttc gctggtccag cgccttgcct gtcatgccag agatggtggc
    18961 aatcggacca agcaattgca ccagagctgt caaataataa gggcccatat caaacattgg
    19021 tccgccgccc atagcataat aaaattcagg atcgggatgc caatgttcat gtccacggct
    19081 catcatgaag gccgtagcgg ctaccggcct gccaatgacc ccttcctcaa tcagcttcaa
    19141 tgccgtctgt atgccggagc cgaagaaggt ctccggtgcg cagccgataa gcagtccctt
    19201 gcggcgggcc agctccaaga cagcctggcc ctgctcacgg gtgaccgcaa gcggcttctc
    19261 tacatagaca tgcttgcctg tctcaagggc tctgagagat acgtcggcgt gaacggccgg
    19321 tatggtcaga ttaatgatga gttcaatctc tggatcagcc aggatctcat ctaccgaata
    19381 tacgttcgga acgttatacg ctgccgcctg ctcctttgct cggccctggt ccagatctgc
    19441 tactgccgac agctccagaa tatcgaagcg ctggcaattt tccatgtaaa ttccgctgat
    19501 tttaccacaa ccgataatgc ccaccttcat tttgttcatg cctggactcc cttcaccttc
    19561 aaaaaatgga taatggaatt tccttactgc atccgacatc atcctgtcta cgctaccgct
    19621 gctggttgtc tgccatgccc gtataagcat ctgccaagga gccgccccgg gcagccgccg
    19681 tctgtttgcc tgccgcagcc cacaggaacc cgctgcgcat catctcggtc acttgaggca
    19741 tctctatgat atctgcgtga tgtcctagcg aattgtagaa gacgcgaccg tttccccaac
    19801 acttcgtcca tacaacgggc atatccaccg gcccattggc tgaatgcggt cccggtacga
    19861 ccgggaagcg tgtggttgcc agcacttcaa ccgccgggtc tacgtggagg tagtactgct
    19921 cgcttttgac ctgaaaatcc tcaatatggt ccagcagcgg gctggagccg cgcttcatgt
    19981 tcaccatata ctccaccccg tcattgccgg gatgtgcaac ccattgcccg cctgtcatga
    20041 actgccagtc cacattgttc cggaaggcat cgcacatgcc gccatggcag cctgctaggc
    20101 ctacgccgct ctgaactgct gccgagacat gattgaccag ctcctgctca atctgtccca
    20161 tggtccacaa cggaacgatt aggtccaggc caagcagctt ctccgcatcc tggtaggctt
    20221 caaggttatt agacacctcc acctcgaacc gctcttcctt caggatccgt tcaaaaatgg
    20281 cagccacctg ctccggctca tgtccgtccc atccgcccca tacaatcagt gccttgctca
    20341 tctgtaatcc actcaccttt cggaatgtga tagttatctt acatttcttc aatggatacc
    20401 cagcggcgct cctctatgga tcgttccacc gcttcaagca cggcctgaca agcgaccccg
    20461 tcgtggaagt tcggcacagg ctgccgtccc tcggagatgg cactcatcag ctcaagcatc
    20521 tcgtgggtga aggtatgctc gaatccgatc gtatgtcccg caggccacca ggcctcggag
    20581 tacttgtgtg ccggatcggt ggcgagcacg cggcggaagc cctgaacgtc cttctcatct
    20641 tgtgtgaaat acacttccag ttcgttcatc cgttcaaagt caaaccgcac actgcccaga
    20701 ctgccgttga tctcgaatga attggtgctc cggtgtccgg ccgcaaaccg tgtggcctcg
    20761 aagctgccca gcgcacctcc ggcgaagcgt gccaggaaca gcgtggcatc atcgaccgtc
    20821 acttctccca tcggcgcatt cgccccggcg ttgcccttgg cgctcaatcc ggtcatctcc
    20881 gaagccagcg ggcgctgctt gatgaacgtc tcgctcatgc cgatcacttc atgaaactcg
    20941 ccgaccagga accgggcgag atcaatcaga tgagcgccaa gatcaccatg agagccagaa
    21001 ccggccactt ccttttgcag ccgccacacc agcgggaagg acgggtccat gatccagtcc
    21061 tgaaggaaaa aggcacggaa atgatagatt ttgcccaggc ggccgctctc gactagctgc
    21121 ttcgccagct ggacagcagg agagaagcgg tagttgaagc cgatcatatg tctgacaccc
    21181 gcttcctccg ctgcctgtag catgtcacgg gaatccgcca gcgagagcgc aagcggcttc
    21241 tcacagaaca gatgcttgcc atggagggca gcctcaatga caatttcctt atgggcatca
    21301 ctcggagcgt tgatgtcaat gagatcaata tcttcacgtt tcaccagatc atgccaattg
    21361 gtaacgcttt cggtccagcc gaactggcgg gcagccgcct gaaccccctg ctcgttgcgt
    21421 ccacagatga cggacatctc cggctgcagc ggggc
//
